Yoshikawa Keisuke 吉川圭介

… Alternative Names

YOSHIKAWA Keisuke 吉川圭介

Less

Researcher Number	10435860
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 埼玉医科大学, 医学部, 准教授 2015 – 2021: 埼玉医科大学, 医学部, 講師 2013 – 2014: 埼玉医科大学, 医学部, 助教 2007 – 2008: Institute for Developmental Research, Aichi Human Service Center, 病理学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / Embryonic/Neonatal medicine Except Principal Investigator Morphological basic dentistry / General pharmacology / Basic Section 38050:Food sciences-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Eating habits / Basic Section 51020:Cognitive and brain science-related
Keywords	Principal Investigator プロスタグランジン / 脂質メディエーター / ミクログリア / 神経炎症 / 神経変性疾患 / 腸脳相関 / 神経細胞死 / 多発性硬化症 / 脱髄疾患 / ミエリン … More / 脂質 / 神経疾患 / 興奮毒性 / ラット / シクロオシキゲナーゼ / LC-ESI-MS / 低酸素性虚血性脳症 / MS / LC-MS / カイニン酸 / プロスタノイド / 神経変性 … More Except Principal Investigator アルツハイマー病 / 認知症 / 多発性硬化症 / 口腔内細菌 / 生活習慣病 / タウ / 人工多能性幹細胞 / 食欲 / 腸内細菌 / ヒト由来腸管上皮細胞株 / 加齢 / エンドカンナビノイド / 食欲調節 / 腸管 / アラキドン酸 / Abクリアランス / 森林資源 / アミロイド / 小児 / メタボリックシンドローム / ドコサヘキサエン酸 / 有酸素運動 / 小児肥満 / 有酸素性運動 / DHA / 身体運動 / 脳神経機能 / 前頭側頭葉変性症 / tau / neuroligin / デグー / シナプス接着分子 / テストステロン / ニューレキシン / ニューロリギン / 歯周病 / 口腔細菌 / 神経疾患 / アルツハイマー / 天然資源由来抽出物 / Aβタンパク質 / クリアランス / Aβ42 / アミロイドβタンパク / 天然由来成分 / 野生型マウス / 天然化合物 / タウタンパク質 / アミロイドβタンパク質 Less

Identification of natural components of Ab clearance and application to Alzheimer's disease therapeutics
- Principal Investigator
  
  丸山敬
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Saitama Medical University
腸管のアラキドン酸とその代謝物が担う食欲調節に関する研究
- Principal Investigator
  
  五十嵐美樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Southen Tohoku Research Institute for Neuroscience
PGD2ミクログリア神経炎症サイクルを制御する腸脳相関の神経変性疾患治療への応用Principal Investigator
- Principal Investigator
  
  吉川圭介
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Saitama Medical University
Elucidation of the gut-brain interaction starting from the lipid sensor in the gastrointestinal tract and its application to the treatment of neurological disordersPrincipal Investigator
- Principal Investigator
  
  Yoshikawa Keisuke
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Saitama Medical University
Elucidation of pathogenic mechanism of sociality impaired dementia
- Principal Investigator
  
  Maruyama Kei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Saitama Medical University
Effects of inflammatory mediators produced by oral bacteria on blood-brain barrier and neurological diseases
- Principal Investigator
  
  Suzuki Masahiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Saitama Medical University
Effects of aerobic exercise and DHA intake on pediatric metabolic syndrome and central nerve system
- Principal Investigator
  
  NAKAO Takehira
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits
- Research Institution
  Kyushu Sangyo University
A novel therapeutic strategy for Alzheimer's disease based on the promotion of clearance mechanism of amyloid beta protein
- Principal Investigator
  
  Iwasa Kensuke
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Saitama Medical University
Readjustment of "amyloid hypothesis" for developing methods to treat Alzheimer disease
- Principal Investigator
  
  Maruyama Kei
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Saitama Medical University
Effectsof oral bacteria on multiple sclerosis and blood brain barrier
- Principal Investigator
  
  TANAKA Motomu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Saitama Medical University
Treatment strategy for hypoxic-ischemic encephalopathy by regulation of prostaglandins bioactivitiesPrincipal Investigator
- Principal Investigator
  
  Yoshikawa Keisuke
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Saitama Medical University
Inhibition of prostanoid productions as prophylaxis and therapeutic strategy for treatment of long lasting neuronal death in excitotoxicityPrincipal Investigator
- Principal Investigator
  
  YOSHIKAWA Keisuke
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Institute for Developmental Research, Aichi Human Service Center

[Journal Article] Long term administration of loquat leaves and their major component, ursolic acid, attenuated endogenous amyloid-b burden and memory impairment2023
- Author(s)
  Iwasa K, Yagishita S, Yagishita-Kyo N, Yamagishi A, Yamamoto S, Yamashina K, Haruta C, Asai M, Maruyama K, Shimizu K, Yoshikawa K
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 16770-16770
- DOI
  10.1038/s41598-023-44098-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06807, KAKENHI-PROJECT-23K06801, KAKENHI-PROJECT-19K07070
[Journal Article] Dietary oleic acid contributes to the regulation of food intake through the synthesis of intestinal oleoylethanolamide2023
- Author(s)
  Miki Igarashi, Kensuke Iwasa, Tetsuhiko Hayakawa, Tsuyoshi Tsuduki, Ikuo Kimura, Kei Maruyama, Keisuke Yoshikawa
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 13 Pages: 1056116-1056116
- DOI
  10.3389/fendo.2022.1056116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05920, KAKENHI-PROJECT-21K06807
[Journal Article] Microglial depletion exacerbates axonal damage and motor dysfunction in mice with cuprizone-induced demyelination2023
- Author(s)
  Yamamoto S, Iwasa K, Yamagishi A, Haruta C, Maruyama K, Yoshikawa K
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 153 Issue: 3 Pages: 94-103
- DOI
  10.1016/j.jphs.2023.08.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06807
[Journal Article] GPR137 inhibits cell proliferation and promotes neuronal differentiation in the Neuro2A cells2022
- Author(s)
  Iwasa K, Yamagishi A, Yamamoto S, Haruta C, Maruyama K, Yoshikawa K
- Journal Title
  
  Neurochemical Research
  
  Volume: November Issue: 3 Pages: 27-27
- DOI
  10.1007/s11064-022-03833-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06807, KAKENHI-PROJECT-18K06899, KAKENHI-PROJECT-18K17933
[Journal Article] Effects of Prostamide/Prostaglandin F Synthase on Melanogenesis and Tumor Metastatic Potential of B16 Melanoma Cells2022
- Author(s)
  Yamagishi A, Iwasa K, Yamamoto S, Haruta C, Maruyama K, Yoshikawa K
- Journal Title
  
  Journal of Pharmaceutical Negative Results
  
  Volume: 13 (3) Pages: 79-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06899
[Journal Article] Effects of Prostamide/Prostaglandin F Synthase on Melanogenesis and Tumor Metastatic Potential of B16 Melanoma Cells2022
- Author(s)
  Yamagishi A, Iwasa K, Yamamoto S, Haruta C, Maruyama K, Yoshikawa K
- Journal Title
  
  Journal of Pharmaceutical Negative Results
  
  Volume: 13 (3) Pages: 79-84
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06807
[Journal Article] Suppressive effect of fruiting bodies of medicinal mushrooms on demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model2022
- Author(s)
  Yamashina K, Yamamoto S, Matsumoto M, Iwasa K, Takeda N, Haruta C, Maruyama K, Shimizu K, *Yoshikawa K
- Journal Title
  
  International Journal of Medicinal Mushrooms
  
  Volume: 24(9) Issue: 9 Pages: 15-24
- DOI
  10.1615/intjmedmushrooms.2022044840
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06807, KAKENHI-PROJECT-18K06899
[Journal Article] A peripheral lipid sensor GPR120 remotely contributes to suppression of PGD2-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus2021
- Author(s)
  Iwasa Kensuke、Yamamoto Shinji、Yamashina Kota、Yagishita-kyo Nan、Maruyama Kei、Awaji Takeo、Takei Yoshinori、Hirasawa Akira、Yoshikawa Keisuke
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 18 Issue: 1 Pages: 304-304
- DOI
  10.1186/s12974-021-02361-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09148, KAKENHI-PROJECT-18K06899, KAKENHI-PROJECT-21K06807, KAKENHI-PROJECT-18K17933
[Journal Article] Feeding regulation by oleoylethanolamide synthesized from dietary oleic acid2021
- Author(s)
  Igarashi Miki、Iwasa Kensuke、Yoshikawa Keisuke
- Journal Title
  
  Prostaglandins, Leukotrienes and Essential Fatty Acids
  
  Volume: 165 Pages: 102228-102228
- DOI
  10.1016/j.plefa.2020.102228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06899, KAKENHI-PROJECT-20K05920
[Journal Article] Testosterone interrupts binding of Neurexin and Neuroligin that are expressed in a highly socialized rodent, Octodon degus2021
- Author(s)
  Yagishita-Kyo Nan、Ikai Yuki、Uekita Tomoko、Shinohara Akio、Koshimoto Chihiro、Yoshikawa Keisuke、Maruyama Kei、Yagishita Sosuke
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 551 Pages: 54-62
- DOI
  10.1016/j.bbrc.2021.03.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06899, KAKENHI-PROJECT-18K07354, KAKENHI-PROJECT-19K07835, KAKENHI-PROJECT-18K15349
[Journal Article] 2-Carba-lysophosphatidic acid is a novel β-lysophosphatidic acid analogue with high potential for lysophosphatidic acid receptor activation and autotaxin inhibition2021
- Author(s)
  Fukasawa Keiko、Gotoh Mari、Uwamizu Akiharu、Hirokawa Takatsugu、Ishikawa Masaki、Shimizu Yoshibumi、Yamamoto Shinji、Iwasa Kensuke、Yoshikawa Keisuke、Aoki Junken、Murakami-Murofushi Kimiko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 17360-17360
- DOI
  10.1038/s41598-021-96931-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06899, KAKENHI-PROJECT-19K07098, KAKENHI-PROJECT-21K06807, KAKENHI-PROJECT-21K15352
[Journal Article] Evaluation of the pharmacokinetics of 2-carba-cyclic phosphatidic acid by liquid chromatography-triple quadrupole mass spectrometry2020
- Author(s)
  Shimizu Yoshibumi、Fukasawa Keiko、Yamamoto Shinji、Shibaike Yuki、Tsukahara Ryoko、Ishikawa Masaki、Iwasa Kensuke、Yoshikawa Keisuke、Gotoh Mari、Murakami-Murofushi Kimiko
- Journal Title
  
  Prostaglandins & Other Lipid Mediators
  
  Volume: 150 Pages: 106450-106450
- DOI
  10.1016/j.prostaglandins.2020.106450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06899, KAKENHI-PROJECT-19K07098, KAKENHI-PROJECT-19K21229
[Journal Article] Ursolic acid treatment suppresses cuprizone-induced demyelination and motor dysfunction via upregulation of IGF-12020
- Author(s)
  Yamamoto Shinji、Sakemoto Chiaki、Iwasa Kensuke、Maruyama Kei、Shimizu Kuniyoshi、Yoshikawa Keisuke
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 144 Issue: 3 Pages: 119-122
- DOI
  10.1016/j.jphs.2020.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06899, KAKENHI-PROJECT-19K21229
[Journal Article] 環状ホスファチジン酸類縁体を用いた多発性硬化症新規治療薬開発プロジェクト2020
- Author(s)
  山本梓司、後藤真里、室伏きみ子、吉川圭介
- Journal Title
  
  ニューサイエンス社 Medical Science Digest
  
  Volume: 9月号 Pages: 1-10
- Data Source
  KAKENHI-PROJECT-18K06899
[Journal Article] 2-Carba cyclic phosphatidic acid inhibits lipopolysaccharide-induced prostaglandin E2 production in a human macrophage cell line2019
- Author(s)
  Shibaike Yuki、Gotoh Mari、Ogawa Chinatsu、Nakajima Shingo、Yoshikawa Keisuke、Kobayashi Tetsuyuki、Murakami-Murofushi Kimiko
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 19 Pages: 100668-100668
- DOI
  10.1016/j.bbrep.2019.100668
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06899, KAKENHI-PROJECT-19K07098, KAKENHI-PROJECT-19J40268
[Journal Article] Treatment of intermittent hypoxia increases phosphorylated tau in the hippocampus via biological processes common to aging.2017
- Author(s)
  Yagishita S, Suzuki S, Yoshikawa K, Iida K, Hirata A, Suzuki M, Takashima A, Maruyama K, Hirasawa A, Awaji T.
- Journal Title
  
  Mol Brain
  
  Volume: 10 Issue: 1 Pages: 2-2
- DOI
  10.1186/s13041-016-0282-7
- NAID
  120005971848
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460341, KAKENHI-PROJECT-25870677, KAKENHI-PROJECT-16K15777, KAKENHI-PROJECT-16K21328, KAKENHI-PLANNED-26117004
[Journal Article] Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating disease2017
- Author(s)
  Yamamoto S, Yamashina K, Ishikawa M, Gotoh M, Iwasa K, Yagishita S, Maruyama K, Murakami-Murofushi K, Yoshikawa K
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 14 Issue: 1 Pages: 142-142
- DOI
  10.1186/s12974-017-0923-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15777, KAKENHI-PROJECT-16K21328, KAKENHI-PROJECT-26860144
[Journal Article] The flavonoid Baicalein attenuates cuprizone-induced demyelination via suppression of neuroinflammation2017
- Author(s)
  Hashimoto M, Yamamoto S, Iwasa K, Yamashina K, Ishikawa M, Maruyama K, Bosetti F, Yoshikawa K
- Journal Title
  
  Brain Research Bulletin
  
  Volume: 135 Pages: 47-52
- DOI
  10.1016/j.brainresbull.2017.09.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15777
[Journal Article] Excitotoxicity-induced prostaglandin D2 production induces sustained microglial activation and delayed neuronal death.2017
- Author(s)
  Iwasa K, Yamamoto S, Yagishita S, Maruyama K, Yoshikawa K.
- Journal Title
  
  J Lipid Res.
  
  Volume: 58 Issue: 4 Pages: 649-655
- DOI
  10.1194/jlr.m070532
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460341, KAKENHI-PROJECT-25870677, KAKENHI-PROJECT-16K15777, KAKENHI-PROJECT-16K21328
[Journal Article] プロスタグランジンF2　FPレセプター阻害は多発性硬化症モデルマウスの神経脱髄と運動障害を改善する2015
- Author(s)
  岩佐健介、山本梓司、高橋茉莉香、鈴木星也、柳下聡介、淡路健雄、丸山敬、吉川圭介
- Journal Title
  
  脂質生化学研究
  
  Volume: ５７ Pages: 85-88
- Data Source
  KAKENHI-PROJECT-25870677
[Journal Article] 脂質メディエーター・環状ホスファチジン酸の変形性関節症と多発性硬化症への効果とその医療応用への展望2015
- Author(s)
  後藤真里、吉川圭介、塚原涼子、室伏きみ子
- Journal Title
  
  脂質栄養学
  
  Volume: ２４ Pages: 41-51
- NAID
  130005068519
- Data Source
  KAKENHI-PROJECT-25870677
[Journal Article] Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction in mice2014
- Author(s)
  Yamamoto S, Gotoh M, Kawamura Y, Yamashina K, Yagishita S, Awaji T, Tanaka M, Maruyama K, Murakami-Murofushi K, Yoshikawa K.
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 741 Pages: 17-24
- DOI
  10.1016/j.ejphar.2014.07.040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460341, KAKENHI-PROJECT-25670781, KAKENHI-PROJECT-25870677, KAKENHI-PROJECT-26860144
[Journal Article] Prostaglandin F2α FP receptor inhibitor reduces demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model2014
- Author(s)
  Iwasa K, Yamamoto S, Takahashi M, Suzuki S, Yagishita S, Awaji T, Maruyama K, Yoshikawa K
- Journal Title
  
  Prostaglandins, Leukotrienes and Essential Fatty Acids
  
  Volume: 91 Issue: 5 Pages: 175-182
- DOI
  10.1016/j.plefa.2014.08.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460341, KAKENHI-PROJECT-25670781, KAKENHI-PROJECT-25870677, KAKENHI-PROJECT-26670126
[Journal Article] Excitotoxicity-induced immediate surge in hippocampal prostanoid production has latent effects that promote chronic progressive neuronal death.2013
- Author(s)
  Yoshikawa K., Kita Y., Furukawa A., Kawamura N., Hasegawa-Ishii S., Chiba Y., Takei S., Maruyama K., Shimizu T., Shimada A.
- Journal Title
  
  Prostaglandins Leukot Essent Fatty Acids.
  
  Volume: 88(5) Issue: 5 Pages: 373-381
- DOI
  10.1016/j.plefa.2013.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J40278, KAKENHI-PROJECT-24229003, KAKENHI-PROJECT-24650190, KAKENHI-PROJECT-25290020, KAKENHI-PROJECT-25460341, KAKENHI-PROJECT-25461565, KAKENHI-PROJECT-25670781, KAKENHI-PROJECT-25870677, KAKENHI-PROJECT-23500436
[Journal Article] The Senescence-accelerated Mouse (SAM) : a higher oxidative stress and agedependent degenerative diseases model.2009
- Author(s)
  Chiba, Y., Shimada, A., Kumagai, N., Yoshikawa, K., Ishii, S., Furukawa, A., Takei, S., Sakura M., Kawamura, N., and Hosokawa, M.
- Journal Title
  
  Neurochem. Res. 34
  
  Pages: 679-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790766
[Journal Article] Neuronal toxicity of expanded polyglutamine depends on intracellular distribution in addition to the expression level.2008
- Author(s)
  Satoh, M., Shimada, A., Kawamura, N., Chiba, Y., Yoshikawa, K., Ishii, S., Furukawa, A., Kumagai, N., and Hosokawa, M.
- Journal Title
  
  Neuropathology. 28
  
  Pages: 485-496
- NAID
  10028191216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790766
[Journal Article] Neuronal toxicity of expanded polyglutamine depends on intracellular distribution in addition to the expression level2008
- Author(s)
  Satoh, M., Shimada, A., Kawa-mura, N., Chiba, Y., Yoshikawa, K., Ishii, S., Furukawa, A., Kumagai, N., and Hosokawa, M.
- Journal Title
  
  Neuropathology in Press
- NAID
  10028191216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790766
[Journal Article] Reduced expression of MAb6B4 epitopes on chondroitin sulfate proteoglycan aggrecan in perineuronal nets from the cerebral cortices of SAMP10 mice : A model for age-dependent neurodegeneration.2008
- Author(s)
  Saitoh, Y., Matsui, F., Chiba, Y., Kawamura, N., Keino, H., Satoh, M., Kumagai, N., Ishii, S., Yoshikawa, K., Shimada, A., Maeda, N., Oohira, A., and Hosokawa, M.
- Journal Title
  
  J. Neurosci. Res. 86
  
  Pages: 1316-1323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790766
[Journal Article] Reduced expression of MAb6B4-epitopes on chondroitin sulfate proteoglycan aggrecan in perineuronal nets from the cerebral cortices of SAMP10 mice, a model for age-dependent neurodegeneration2008
- Author(s)
  Saitoh, Y., Matsui, F., Chiba, Y., Kawamura, N., Keino, H., Satoh, M., Kumagai, N., Ishii, S., Yoshikawa, K., Shimada, A., Maeda, N., Oohira, A., and Hosokawa, M.
- Journal Title
  
  Journal of Neuroscience Research in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790766
[Journal Article] The Senescence-accelerated Mouse(SAM): a higher oxidative stress and age-dependent degenerative diseases model.2008
- Author(s)
  Chiba, Y., Shimada, A., Kumagai, N., Yoshikawa, K., Ishii, S., Furukawa, A., Takei, S., Sakura M., Kawamura, N., Hosokawa, M.
- Journal Title
  
  Neurochem. Res. (印刷中 Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790766
[Journal Article] Involvement of pro-inflammatory cytokines and microglia in an age-associated neurodegeneration model, the SAMP10 mouse.2007
- Author(s)
  Kumagai, N., Chiba, Y., Hosono, M., Fujii, M., Kawamura, N., Keino, H., Yoshikawa, K., Ishii, S., Saitoh, Y., Satoh, M., Shimada, A., and Hosokawa, M.
- Journal Title
  
  Brain Res. 1185
  
  Pages: 75-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790766
[Journal Article] Involvement of pro-inflammatory cytokines and microglia in an age-associated neurodegeneration model, the SAMP10 mouse2007
- Author(s)
  Kumagai, N., Chiba, Y., Hosono, M., Fujii, M., Kawamura, N., Keino, H., Yoshikawa. K., Ishii, S., Saitoh, Y., Satoh, M., Shimada, A., and Hosokawa, M.
- Journal Title
  
  Brain Research 1185
  
  Pages: 75-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790766
[Patent] 脱髄疾患治療薬2014
- Inventor(s)
  室伏きみ子、後藤真里、丸山敬、吉川圭介、山本梓司
- Industrial Property Rights Holder
  国立大学法人お茶の水女子大学、学校法人埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-012859
- Filing Date
  2014-01-28
- Overseas
- Data Source
  KAKENHI-PROJECT-25870677
[Patent] 脱髄疾患治療薬2014
- Inventor(s)
  室伏きみ子、後藤真里、丸山敬、吉川圭介、山本梓司
- Industrial Property Rights Holder
  国立大学法人お茶の水女子大学、法人埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-012859
- Filing Date
  2014-01-28
- Overseas
- Data Source
  KAKENHI-PROJECT-25670781
[Patent] タウタンパク質のリン酸化が亢進された非ヒトモデル動物の製造方法2013
- Inventor(s)
  栁下聡介，鈴木正彦，淡路健雄，吉川圭介，丸山敬，鈴木星也
- Industrial Property Rights Holder
  学校法人埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-130358
- Filing Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-25460341
[Patent] タウタンパク質のリン酸化が亢進された非ヒトモデル動物の製造方法2013
- Inventor(s)
  栁下聡介，鈴木正彦，淡路健雄，吉川圭介，丸山敬，鈴木星也
- Industrial Property Rights Holder
  栁下聡介，鈴木正彦，淡路健雄，吉川圭介，丸山敬，鈴木星也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-130358
- Filing Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-25870677
[Patent] タウタンパク質のリン酸化が亢進された非ヒトモデル動物の製造方法2013
- Inventor(s)
  柳下聡介、鈴木正彦、淡路健雄、吉川圭介、丸山敬、鈴木星也
- Industrial Property Rights Holder
  法人埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-130358
- Filing Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-25670781
[Presentation] ビワ葉とウルソール酸の長期投与による内因性アミロイドbタンパク質の減少と認知機能の改善2023
- Author(s)
  岩佐健介、山本梓司、山岸杏、春田力、清水邦義、吉川圭介
- Organizer
  第24回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 肥満における腸管のアラキドン酸やその代謝物の変動と摂食行動の関連性2023
- Author(s)
  五十嵐美樹、山本梓司、岩佐健介、丸山敬、吉川圭介
- Organizer
  脂質栄養学会第32回大会
- Data Source
  KAKENHI-PROJECT-23K05122
[Presentation] ドーパミン可視化プローブを用いたアストロサイトにおけるドーパミントランスポーターの機能解析2023
- Author(s)
  小堺亜美、小野寺香奈、砂川糊幸、飯塚佳子、吉川圭介、太田悦郎
- Organizer
  第46回日本神経科学会
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] A peripheral lipid sensor GPR120 remotely contributes to suppression of PGD2-microglia-provoked neuroinflammation and neurodegeneration2023
- Author(s)
  Yoshikawa K, Iwasa K, Yamamoto S, Haruta C, Maruyama K
- Organizer
  The International Society of Neurochemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 上小脳脚におけるミクログリア除去は多発性硬化症モデルマウスの軸索損傷と運動機能不全を悪化させる2023
- Author(s)
  山本梓司、岩佐健介、山岸杏、春田力、丸山敬、吉川圭介
- Organizer
  第25回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 腸管PUFA/GPR120シグナルによる海馬PGD2-ミクログリア神経炎症サイクルの遠隔抑制2023
- Author(s)
  岩佐健介、山本梓司、吉川圭介
- Organizer
  第32回日本脂質栄養学会
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 神経細胞の増殖・分化におけるオーファン受容体GPR137の機能解析2022
- Author(s)
  山岸杏、岩佐健介、山本梓司、春田力、丸山敬、吉川圭介
- Organizer
  第32回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 腸管PUFA/GPR120シグナルによる海馬PGD2-ミクログリア神経炎症サイクルの遠隔抑制2022
- Author(s)
  岩佐健介、吉川圭介
- Organizer
  第64回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 食事性肥満原因遺伝子GPR120が神経炎症、海馬発達に及ぼす影響2022
- Author(s)
  岩佐健介、山本梓司、春田力、平澤明、丸山敬、吉川圭介
- Organizer
  第31回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 腸管PUFA/GPR120シグナルと海馬神経炎症における腸脳相関の解明2022
- Author(s)
  岩佐健介、山本梓司、武井義則、平澤明、丸山敬、吉川圭介
- Organizer
  第146回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 腸管脂質センサーを起点とした腸脳相関によるPGD2－ミクログリア神経炎症サイクルの抑制2022
- Author(s)
  吉川圭介、岩佐健介、山本梓司、春田力、丸山敬
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] メラノーマ細胞における脂肪酸合成酵素の機能解析2022
- Author(s)
  山岸杏、岩佐健介、山本梓司、丸山　敬、吉川圭介
- Organizer
  第31回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 多発性硬化症モデルマウスの運動機能におけるミクログリアの寄与2022
- Author(s)
  山本梓司、岩佐健介、春田力、丸山敬、吉川圭介
- Organizer
  第31回神経行動薬理若手研究者の集い
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] Suppressive effect of fruiting bodies of medicinal mushrooms on demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model2022
- Author(s)
  Yamashina K, Yamamoto S, Matsumoto M, Iwasa K, Takeda N, Haruta C, Maruyama K, Shimizu K, Yoshikawa K
- Organizer
  11th Asia Natural Product Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 食事性肥満原因遺伝子GPR120が神経炎症、海馬発達に及ぼす影響2022
- Author(s)
  岩佐健介、山本梓司、春田力、平澤明、丸山敬、吉川圭介
- Organizer
  第31回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 多発性硬化症モデルマウスの運動機能におけるミクログリアの寄与2022
- Author(s)
  山本梓司、岩佐健介、春田力、丸山敬、吉川圭介
- Organizer
  第31回神経行動薬理若手研究者の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] Suppressive effect of fruiting bodies of medicinal mushrooms on demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model2022
- Author(s)
  Yamashina K, Yamamoto S, Matsumoto M, Iwasa K, Takeda N, Haruta C, Maruyama K, Shimizu K, Yoshikawa K
- Organizer
  11th Asia Natural Product Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 神経炎症におけるプロスタグランジンとグリア活性化―依存的か非依存的か？2022
- Author(s)
  吉川圭介
- Organizer
  第45回日本分子生物学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 腸管脂質センサーを起点とした腸脳相関によるPGD2－ミクログリア神経炎症サイクルの抑制2022
- Author(s)
  吉川圭介、岩佐健介、山本梓司、春田力、丸山敬
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 神経細胞の増殖・分化におけるオーファン受容体GPR137の機能解析2022
- Author(s)
  山岸杏、岩佐健介、山本梓司、春田力、丸山敬、吉川圭介
- Organizer
  第32回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] Dysfunction of a peripheral lipid sensor GPR120 causes PGD2-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus2022
- Author(s)
  岩佐健介、山本梓司、平澤明、丸山敬、吉川圭介
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] Dysfunction of a peripheral lipid sensor GPR120 causes PGD2-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus2022
- Author(s)
  岩佐健介、山本梓司、平澤明、丸山敬、吉川圭介
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 腸管PUFA/GPR120シグナルと海馬神経炎症における腸脳相関の解明2022
- Author(s)
  岩佐健介、山本梓司、武井義則、平澤明、丸山敬、吉川圭介
- Organizer
  第146回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] メラノーマ細胞における脂肪酸合成酵素の機能解析2022
- Author(s)
  山岸杏、岩佐健介、山本梓司、丸山　敬、吉川圭介
- Organizer
  第31回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 神経炎症におけるプロスタグランジンとグリア活性化―依存的か非依存的か？2022
- Author(s)
  吉川圭介
- Organizer
  第45回日本分子生物学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 腸管PUFA/GPR120シグナルによる海馬PGD2-ミクログリア神経炎症サイクルの遠隔抑制2022
- Author(s)
  岩佐健介、吉川圭介
- Organizer
  第64回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] A peripheral lipid sensor GPR120 remotely suppresses Prostaglandin D2-Microglia Neuroinflammation Cycle2021
- Author(s)
  Yoshikawa K
- Organizer
  Asia Natural Product Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] A peripheral lipid sensor GPR120 remotely suppresses Prostaglandin D2-Microglia Neuroinflammation Cycle2021
- Author(s)
  Yoshikawa K
- Organizer
  Asia Natural Product Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06807
[Presentation] 記憶学習およびアミロイドβタンパク質に対する森林由来天然資源の効果2020
- Author(s)
  阿部琴絵、岩佐健介、浅井将、丸山敬、清水邦義、吉川圭介
- Organizer
  第29回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] Effect of forest bioresources for amyloid-β protein and working memory performance2020
- Author(s)
  岩佐健介、浅井将、丸山敬、清水邦義、吉川圭介
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 記憶学習およびアミロイドβタンパク質に対する森林由来天然資源の効果2020
- Author(s)
  阿部琴絵、岩佐健介、浅井将、丸山敬、清水邦義、吉川圭介
- Organizer
  第29回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K07354
[Presentation] ウルソール酸の脱髄抑制効果2020
- Author(s)
  酒本千誠、山本梓司、岩佐健介、丸山敬、清水邦義、吉川圭介
- Organizer
  第29回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 脱髄モデルマウスにおける食用キノコの脱髄抑制効果2020
- Author(s)
  武田乃ノ佳、山本梓司、岩佐健介、丸山敬、清水邦義、吉川圭介
- Organizer
  第29回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 神経炎症における生理活性脂質 ― 創薬への応用と腸脳相関2020
- Author(s)
  吉川圭介
- Organizer
  第63回日本神経化学会
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 生理活性脂質を基軸とした生化、病理、薬理学的研究キャリアパス2020
- Author(s)
  吉川圭介
- Organizer
  第93回日本生化学会
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 脱髄モデルマウスにおける食用キノコの脱髄抑制効果2020
- Author(s)
  武田乃ノ佳、山本梓司、岩佐健介、丸山敬、清水邦義、吉川圭介
- Organizer
  第29回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K07354
[Presentation] ウルソール酸の脱髄抑制効果2020
- Author(s)
  酒本千誠、山本梓司、岩佐健介、丸山敬、清水邦義、吉川圭介
- Organizer
  第29回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K07354
[Presentation] 食事性肥満が神経炎症、海馬発達に及ぼす影響2019
- Author(s)
  岩佐健介、鈴木正彦、丸山敬、平澤明、吉川圭介
- Organizer
  第28回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-16K15777
[Presentation] Cyclic phosphatidic acid derivative is a novel drug candidate for multiple sclerosis2019
- Author(s)
  Yamamoto S, Iwasa K, Gotoh M, Maruyama K, Murofushi K, Yoshikawa K
- Organizer
  7th China-Japan joint meeting of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 環状ホスファチジン酸のミエリン再生促進メカニズム解析2019
- Author(s)
  曽我健斗、山本梓司、鈴木正彦、後藤真里、室伏きみ子、吉川圭介
- Organizer
  第28回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] Cyclic phosphatidic acid derivative is a novel drug candidate for multiple sclerosis2019
- Author(s)
  Yamamoto S, Iwasa K, Gotoh M, Maruyama K, Murofushi K, Yoshikawa K
- Organizer
  7th China-Japan joint meeting of basic and clinical pharmacology
- Data Source
  KAKENHI-PROJECT-18K07354
[Presentation] 脱髄モデルマウスにおける食用キノコの脱髄抑制効果2019
- Author(s)
  武田乃ノ佳、山本梓司、岩佐健介、丸山敬、清水邦義、吉川圭介
- Organizer
  第29回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 環状ホスファチジン酸のミエリン再生促進メカニズム解析2019
- Author(s)
  曽我健斗、山本梓司、鈴木正彦、後藤真里、室伏きみ子、吉川圭介
- Organizer
  第28回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-16K15777
[Presentation] 自然発症アルツハイマー病モデル・デグーの疾患関連遺伝子解析2019
- Author(s)
  小杉山捷、鈴木正彦、吉川圭介、栁下‐姜楠
- Organizer
  第28回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-16K15777
[Presentation] 記憶学習およびアミロイドβタンパク質に対する森林由来天然資源の効果2019
- Author(s)
  阿部琴絵、岩佐健介、浅井将、丸山敬、清水邦義、吉川圭介
- Organizer
  第29回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 自然発症アルツハイマー病モデル・デグーの疾患関連遺伝子解析2019
- Author(s)
  小杉山捷、鈴木正彦、吉川圭介、栁下‐姜楠
- Organizer
  第28回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] ウルソール酸の脱髄抑制効果2019
- Author(s)
  酒本千誠、山本梓司、岩佐健介、丸山敬、清水邦義、吉川圭介
- Organizer
  第29回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] 食事性肥満が神経炎症、海馬発達に及ぼす影響2019
- Author(s)
  岩佐健介、鈴木正彦、丸山敬、平澤明、吉川圭介
- Organizer
  第28回神経行動薬理若手の集い
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in Multiple Screlosis mouse models2018
- Author(s)
  K. Yoshikawa, S Yamamoto, K Iwasa, M Gotoh, K Maruyama, K. Murakami-Murofushi
- Organizer
  The 11th Pan-Asian Committees on Treatment and Research in Multiple Sclerosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in Multiple Screlosis mouse models2018
- Author(s)
  K. Yoshikawa, S Yamamoto, K Iwasa, M Gotoh, K Maruyama, K. Murakami-Murofushi
- Organizer
  The 11th Pan-Asian Committees on Treatment and Research in Multiple Sclerosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15777
[Presentation] Disruption of satiety factor OEA production in the gut by imbalanced nutrition of fat and carbohydrate2018
- Author(s)
  M. Igarashi, K. Iwasa, K. Yoshikawa, D. Piomelli
- Organizer
  The 13th Congress of The International Society For The Study Of Fatty Acids And Lipids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15777
[Presentation] Experimental trial to evaluate the preventive effect of aerobic exercise on the neuronal disease2018
- Author(s)
  T. Nakao, K. Iwasa, M. Ishikawa, S. Yamamoto, T. Adachi, K. Yoshikawa
- Organizer
  The 23rd annual conference of East Asian sport and exercise science society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15777
[Presentation] Experimental trial to evaluate the preventive effect of aerobic exercise on the neuronal disease2018
- Author(s)
  Nakao Takehira, Iwasa Kensuke, Ishikawa Masaki, Yamamoto Shinji, Adachi Takahiro, Yoshikawa Keisuke
- Organizer
  The 23rd Annual Conference of the East Asian Sport and Exercise Science Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21544
[Presentation] Disruption of satiety factor OEA production in the gut by imbalanced nutrition of fat and carbohydrate.2018
- Author(s)
  M. Igarashi, K. Iwasa, K. Yoshikawa, D. Piomelli
- Organizer
  The 13th Congress of The International Society For The Study Of Fatty Acids And Lipids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] Experimental trial to evaluate the preventive effect of aerobic exercise on the neuronal disease2018
- Author(s)
  T. Nakao, K. Iwasa, M. Ishikawa, S. Yamamoto, T. Adachi, K. Yoshikawa
- Organizer
  The 23rd annual conference of East Asian sport and exercise science society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06899
[Presentation] Cyclic phosphatidic acid derivative is a novel drug candidate for multiple sclerosis2017
- Author(s)
  K. Yoshikawa, S. Yamamoto, K. Yamashina, K. Iwasa, M. Gotoh, M. Suzuki, K. Maruyama, K. Murakami-Murofushi
- Organizer
  第90回　日本薬理学会年会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] Cyclic phosphatidic acid derivative is a novel drug candidate for multiple sclerosis2017
- Author(s)
  K. Yoshikawa, S. Yamamoto, M Yamashina, M. K Iwasa, Gotoh, T, M. Suzuki, K. Maruyama, K. Murakami-Murofushi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K15777
[Presentation] 食事性肥満の世代間伝達が認知機能に及ぼす影響2017
- Author(s)
  吉川圭介、江口寧々、岩佐健介、山本梓司、丸山敬、平澤明
- Organizer
  第26回　神経行動薬理若手研究者の集い
- Place of Presentation
  福岡県福岡市
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] 食事性肥満の世代間伝達が認知機能に及ぼす影響2017
- Author(s)
  吉川圭介、江口寧々、岩佐健介、山本梓司、丸山敬、平澤明
- Organizer
  第26回神経行動薬理若手研究者の集い
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] Cyclic phosphatidic acid derivative is a novel drug candidate for multiple sclerosis2017
- Author(s)
  K. Yoshikawa, S. Yamamoto, M Yamashina, M. K Iwasa, Gotoh, T, M. Suzuki, K. Maruyama, K. Murakami-Murofushi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] 神経変性疾患における脂質メディエーターの作用機序と創薬的展望2016
- Author(s)
  吉川圭介
- Organizer
  神経行動薬理若手研究者の集い
- Place of Presentation
  ソニックシティホール（埼玉県さいたま市）
- Year and Date
  2016-03-08
- Invited
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] Cyclic phosphatidic acid derivative is a novel drug candidate for multiple sclerosis2016
- Author(s)
  K. Yoshikawa, S. Yamamoto, M. Gotoh, T. Shimizu, M. Hashimoto, K. Yamashina, M. Suzuki, K. Maruyama, K. Murakami-Murofushi
- Organizer
  14th Meeting of The Asian-pacific society for Neurochemistry
- Place of Presentation
  Kuala Lumpur, Malaysia
- Year and Date
  2016-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15777
[Presentation] 多発性硬化症の新規治療薬候補・環状ホスファチジン誘導体2016
- Author(s)
  山本梓司、清水嘉文、後藤真里、橋本真歩、山科孝太、岩佐健介、丸山敬、室伏きみ子、吉川圭介
- Organizer
  第58回日本脂質生化学会
- Place of Presentation
  秋田
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] 多発性硬化症の新規治療薬候補・環状ホスファチジン酸誘導体2016
- Author(s)
  山本梓司、清水嘉文、後藤真理、橋本真歩、山科孝太、岩佐健介、丸山敬、室伏きみ子、吉川圭介
- Organizer
  第58回　日本資質生化学会
- Place of Presentation
  秋田県秋田市
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] Effects of oral bacteria on multiple sclerosis2016
- Author(s)
  岩佐健介、山本梓司、山科孝太、丸山敬、吉川圭介
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  神奈川県横浜市（パシフィコ横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26670126
[Presentation] 内在性リン酸化タウ増加モデルのマイクロアレイ解析2016
- Author(s)
  栁下聡介、鈴木星也、吉川圭介、飯田桂子、平田理子、鈴木正彦、高島明彦、丸山敬、平澤明、淡路健雄
- Organizer
  第35回日本認知症学会
- Place of Presentation
  東京
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K15777
[Presentation] 多発性硬化症の新規治療薬候補ー環状ホスファチジン酸誘導体2016
- Author(s)
  山本梓司，清水嘉文，後藤真里，丸山敬，室伏きみ子，吉川圭介
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2016-03-10
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] Cyclic phosphatidic acid derivative is a novel drug candidate for multiple sclerosis2016
- Author(s)
  Keisuke Yoshikawa, Shinji Yamamoto, Mari Gotoh, Takabumi Shimizu, Miho Hashimoto, Kota Yamashina, Masahiko Suzuki, Kei Maruyama, Kimiko Murakami-Murofushi
- Organizer
  14th Meeting of the Asian-Pacific Society for NEUROCHEMISTRY
- Place of Presentation
  MALAYSIA,KUALA LUMPUR
- Year and Date
  2016-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] 口腔内細菌の多発性硬化症への影響2016
- Author(s)
  岩佐健介，山本梓司，山科孝太，丸山敬，吉川圭介
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2016-03-10
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] 興奮毒性誘発遅発性神経細胞死におけるプロスタグランジンの生理活性解析2016
- Author(s)
  吉川圭介，山本梓司，丸山敬，岩佐健介
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] 内在性リン酸化タウ増加モデルのマイクロアレイ解析2016
- Author(s)
  栁下聡介、鈴木星也、吉川圭介、飯田桂子、平田理子、鈴木正彦、高島明彦、丸山敬、平澤明、淡路健雄
- Organizer
  第35回日本認知症学会
- Place of Presentation
  東京
- Year and Date
  2016-12-11
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] 内在性リン酸化タウ増加モデルのマイクロアレイ解析2016
- Author(s)
  栁下聡介，鈴木星也，吉川圭介，飯田桂子，平田理子，鈴木正彦，高島明彦，丸山敬，平澤明，淡路健雄
- Organizer
  第35回　日本認知症学会
- Place of Presentation
  東京
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] Cyclic phosphatidic acid derivative is a novel drug candidate for multiple sclerosis2016
- Author(s)
  K. Yoshikawa, S. Yamamoto, M. Gotoh, T. Shimizu, M. Hashimoto, K. Yamashina, M. Suzuki, K. Maruyama, K. Murakami-Murofushi
- Organizer
  14th Meeting of The Asian-pacific society for Neurochemistry
- Place of Presentation
  Kuala Lumpur, Malaysia
- Year and Date
  2016-08-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] 口腔内細菌の多発性硬化症への影響2015
- Author(s)
  吉川圭介、山本梓司、山科孝太、岩佐健介、丸山敬、田名求
- Organizer
  第132回日本薬理学会関東支部会
- Place of Presentation
  明海大学（千葉県浦安市）
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] プロスタグランジンF2α FPレセプター阻害は多発性硬化症モデルマウスの神経脱髄と運動障害を改善する2015
- Author(s)
  岩佐健介、山本梓司、高橋茉莉香、鈴木星也、柳下聡介、淡路健雄、丸山敬、吉川圭介
- Organizer
  第57回日本脂質生化学会
- Place of Presentation
  東京都千代田区(一橋大学)
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26670126
[Presentation] Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction2015
- Author(s)
  Yamamoto S, Gotoh M, Kawamura Y, Yagishita S, Awaji T, Tanaka M, Maruyama K, Murakami-Murofushi K, Yoshikawa K
- Organizer
  ECTRIMS (European committee for treatment and research in Multiple Sclerosis)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] プロスタグランジンF2α　FPレセプター阻害は多発性硬化症モデルマウスの神経脱髄と運動障害を改善する2015
- Author(s)
  岩佐健介、山本梓司、高橋茉莉香、鈴木星也、柳下聡介、淡路健雄、丸山敬、吉川圭介
- Organizer
  第57回日本脂質生化学会
- Place of Presentation
  東京都（一橋大学）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction2015
- Author(s)
  Yamamoto S, Gotoh M, Kawamura Y, Yagishita S, Awaji T, Tanaka M, Maruyama K, Murakami-Murofushi K, Yoshikawa K
- Organizer
  ECTRIMS (European committee for treatment and research in Multiple Sclerosis)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] Prostaglandin F2α FP receptor inhibitor reduce demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model2015
- Author(s)
  岩佐　健介、山本梓司、高橋　茉莉香、鈴木　星也、柳下　聡介、淡路　健雄、丸山　敬、吉川　圭介
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26670126
[Presentation] プロスタグランジンF2alpha;　FPレセプター阻害は多発性硬化症モデルマウスの神経脱髄と運動障害を改善する2015
- Author(s)
  岩佐健介、山本梓司、高橋茉莉香、鈴木星也、柳下聡介、淡路健雄、丸山敬、吉川圭介
- Organizer
  第57回日本脂質生化学会
- Place of Presentation
  一橋大学（東京都千代田区）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] 口腔内細菌の多発性硬化症への影響2015
- Author(s)
  吉川圭介、山本梓司、山科孝太、岩佐健介、丸山敬、田名求
- Organizer
  第132回日本薬理学会関東支部会
- Place of Presentation
  浦安市（明海大学）
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] 2-Carba-cyclic phosphatidic acid, a chemically synthesized cyclic phosphatidic acid derivative, is a novel drug candidate for multiple sclerosis2015
- Author(s)
  Shinji Yamamoto, Yoshibumi Shimizu, Mari Gotoh, Kei Maruyama, Kimiko Murakami-Murofushi, Keisuke Yoshikawa
- Organizer
  第57回日本神経化学会大会
- Place of Presentation
  さいたま市（ソニックシティ）
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] Prostaglandin F2α FP receptor inhibitor reduces demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model2015
- Author(s)
  岩佐健介、山本梓司、高橋茉莉香、鈴木星也、柳下聡介、淡路健雄、丸山敬、吉川圭介
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] 環状ホスファチジン酸による中枢性脱髄抑制効果2014
- Author(s)
  山本梓司、川村勇樹、後藤真里、吉川圭介、室伏きみ子、丸山敬
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25670781
[Presentation] Effect of extract X for working memory performance and amyloid-β protein in mice2014
- Author(s)
  岩佐健介、譚慧、緑川沙也華、根本みく、水嶋麻未、吉川圭介、清水邦義、丸山敬
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  宮城県　仙台市
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] Effect of extract X for working memory performance and amyloid-β protein in mice2014
- Author(s)
  岩佐健介、譚慧、緑川沙也華、根本みく、水嶋麻未、吉川圭介、清水邦義、丸山敬
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] 環状ホスファチジン酸による中枢性脱髄抑制効果2014
- Author(s)
  山本梓司、川村勇樹、後藤真里、吉川圭介、室伏きみ子、丸山敬
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] Effect of extract X for working memory performance and amyloid-β protein in mice2014
- Author(s)
  岩佐健介、譚慧、緑川沙也華、根本みく、水嶋麻未、吉川圭介、清水邦義、丸山敬
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25670781
[Presentation] 環状ホスファチジン酸による中枢性脱髄抑制効果2013
- Author(s)
  山本梓司、吉川圭介、川村勇樹、後藤真理、室伏きみ子、丸山敬
- Organizer
  第129回日本薬理学会関東支部会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-25670781
[Presentation] 脱髄疾患におけるアラキドン酸カスケードの寄与2013
- Author(s)
  山本梓司、吉川圭介、Sara Palumbo、Francesca Bosetti、丸山敬
- Organizer
  平成25年度日本生化学会関東支部会
- Place of Presentation
  甲府市　山梨大学
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] 環状ホスファチジン酸による中枢性脱髄抑制効果2013
- Author(s)
  山本梓司、吉川圭介、川村勇樹、後藤真理、室伏きみ子、丸山敬
- Organizer
  第129回日本薬理学会関東支部会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] 脱髄疾患におけるアラキドン酸カスケードの寄与2013
- Author(s)
  吉川圭介、Sara Palumbo、山本梓司、高橋茉莉香、丸山敬、Francesca Bosetti
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  宮城県松島
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] 脱髄疾患におけるアラキドン酸カスケードの寄与2013
- Author(s)
  吉川圭介、Sara Palumbo、山本梓司、高橋茉莉香、丸山敬、Francesca Bosetti
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  宮城県松島町
- Data Source
  KAKENHI-PROJECT-25670781
[Presentation] 脱髄疾患におけるアラキドン酸カスケードの生理活性2013
- Author(s)
  山本梓司, 吉川圭介, Sara Palumbo, 丸山敬, Francesca Bosetti
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] 脱髄疾患におけるアラキドン酸カスケードの寄与2013
- Author(s)
  吉川圭介、Sara Palumbo、山本梓司、高橋茉莉香、丸山敬、Francesca Bosetti
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  宮城県松島町
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] 脱髄疾患におけるアラキドン酸カスケードの生理活性2013
- Author(s)
  山本梓司, 吉川圭介, Sara Palumbo, 丸山敬, Francesca Bosetti
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25670781
[Presentation] 脱髄疾患におけるアラキドン酸カスケードの寄与2013
- Author(s)
  山本梓司、吉川圭介、Sara Palumbo、Francesca Bosetti、丸山敬
- Organizer
  平成25年度日本生化学会関東支部会
- Place of Presentation
  甲府市
- Data Source
  KAKENHI-PROJECT-25670781
[Presentation] 脱髄疾患におけるアラキドン酸カスケードの寄与2013
- Author(s)
  山本梓司、吉川圭介、Sara Palumbo、Francesca Bosetti、丸山敬
- Organizer
  平成25年度日本生化学会関東支部会
- Place of Presentation
  甲府市
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] 老化促進モデルマウスの興奮毒性に対するミクログリアの応答異常と海馬の脆弱性2008
- Author(s)
  石井さなえ, 島田厚良, 千葉陽一, 吉川圭介, 古川絢子, 河村則子, 細川昌則
- Organizer
  第49回日本神経病理学会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10マウス由来培養神経細胞に誘導したユビキチン化封入体形成による神経突起退縮2008
- Author(s)
  千葉陽一, 島田厚良, 河村則子, 吉川圭介, 石井さなえ, 古川絢子, 武井史郎, 細川昌則
- Organizer
  日本基礎老化学会
- Place of Presentation
  松本市
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] ミクログリアの神経保護機能低下が加齢性神経変性を引き起こす2008
- Author(s)
  石井さなえ, 千葉陽一, 吉川圭介, 古川絢子, 河村則子, 武井史郎, 細川昌則, 島田厚良, 梅垣宏行
- Organizer
  第13回グリア研究会
- Place of Presentation
  東京都千代田区
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10マウス由来培養神経細胞に誘導したaggresome関連ubiquitin陽性封入体形成による神経突起退縮2008
- Author(s)
  千葉陽一, 島田厚良, 河村則子, 吉川圭介, 石井さなえ, 古川絢子, 細川昌則
- Organizer
  第49回日本神経病理学会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMに関する実験的研究136.老化促進モデルマウスの興奮毒性に対するミクログリアの応答異常と海馬の脆弱性2008
- Author(s)
  石井さなえ、島田厚良、千葉陽一、吉川圭介、古川絢子、河村則子、細川昌則
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢市
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] ミクログリアの神経保護機能低下が加齢性神経変性を引き起こす2008
- Author(s)
  石井さなえ, 島田厚良, 千葉陽一, 吉川圭介, 古川絢子, 河村則子, 細川昌則
- Organizer
  老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  京都市
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10の加齢性神経変性に伴うα-internexinの早期リン酸化に関するプロテオミクス解析2008
- Author(s)
  古川絢子, 島田厚良, 及川伸二, 千葉陽一, 吉川圭介, 石井さなえ, 河村則子, 細川昌則
- Organizer
  老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  京都市
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 加齢性神経変性モデルSAMP10マウスに見られるミクログリアの神経保護機能の減弱2008
- Author(s)
  石井さなえ, 島田厚良, 千葉陽一, 吉川圭介, 古川絢子, 河村則子, 細川昌則
- Organizer
  日本基礎老化学会
- Place of Presentation
  松本市
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMに関する実験的研究136. 老化促進モデルマウスの興奮毒性に対するミクログリアの応答異常と海馬の脆弱性2008
- Author(s)
  石井さなえ, 島田厚良, 千葉陽一, 吉川圭介, 古川絢子, 河村則子, 細川昌則
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢市
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 老化促進モデルマウスの興奮毒性に対するミクログリアの応答異常と海馬の脆弱性2008
- Author(s)
  石井さなえ, 島田厚良, 千葉陽一, 吉川圭介, 古川絢子, 河村則子, 細川昌則
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京都千代田区
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10マウス由来培養神経細胞に誘導したaggresome関連ubiquitin陽性封入体形成と神経突起退縮2008
- Author(s)
  千葉陽一, 島田厚良, 河村則子, 吉川圭介, 石井さなえ, 古川絢子, 武井史郎, 細川昌則
- Organizer
  老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  京都市
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10の加齢性神経変性に伴うタンパク質発現変動のプロテオミクス解析2008
- Author(s)
  古川絢子, 島田厚良, 及川伸二, 千葉陽一, 吉川圭介, 石井さなえ, 河村則子, 細川昌則
- Organizer
  日本基礎老化学会
- Place of Presentation
  松本市
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10マウス由来培養神経細胞におけるaggresome関連ubiquitin陽性封入体形成により誘導される神経突起退縮2008
- Author(s)
  千葉陽一, 島田厚良, 河村則子, 吉川圭介, 石井さなえ, 古川絢子, 武井史郎, 細川昌則
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京都千代田区
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] プロスタノイド産生抑制を機軸とした持続性神経細胞死の治療戦略2008
- Author(s)
  吉川圭介, 河村則子, 石井さなえ, 古川絢子, 千葉陽一, 島田厚良
- Organizer
  第13回グリア研究会
- Place of Presentation
  東京都千代田区
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 加齢性神経変性モデルSenescence-accelerated mice SAMP10におけるエイコサノイドの網羅的定量解析2007
- Author(s)
  吉川圭介、北芳博、島田厚良、石井さなえ、古川絢子、河村則子、千葉陽一、熊谷直子、清水孝雄、細川昌則
- Organizer
  日本生化学会BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 加齢変性モデルSAMP10マウスの海馬の興奮毒性に対する脆弱性とミクログリアの応答異常2007
- Author(s)
  島田厚良、石井さなえ、吉川圭介、千葉陽一、河村則子、古川絢子、細川昌則
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 神経変性モデルSAMP10マウスにおけるミクログリア退行変性の早期出現2007
- Author(s)
  石井さなえ、島田厚良、吉川圭介、千葉陽一、河村則子、古川絢子、細川昌則
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10マウスにおけるユビキチン化封入体系性の病的意義に関す巣培養系を用いた解析2007
- Author(s)
  千葉陽一、島田厚良、熊谷直子、河村則子、吉川圭介、石井さなえ、細川昌則
- Organizer
  第48回日本神経病理学会総会・学術研究会
- Place of Presentation
  東京
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 老化促進モデルマウスSAMP1系統における被毛と皮膚の加齢変化2007
- Author(s)
  佐倉正明、平出孝枝、河村則子、千葉陽一、熊谷直子、吉川圭介、石井さなえ、古川絢子、島田厚良、細川昌則
- Organizer
  第22回老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  酒田
- Year and Date
  2007-07-26
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10を用いた加齢性中枢神経変性における神経炎症の関わりについて-proinflammatory cytokinesの加齢変化と脳萎縮2007
- Author(s)
  熊谷直子、千葉陽一、細野正道、藤井庄人、河村則子、吉川圭介、石井さなえ、古川絢子、島田厚良、細川昌則
- Organizer
  第22回老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  酒田
- Year and Date
  2007-07-27
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 海馬興奮毒性における二相性プロスタノイド産生(脂質の網羅的質量解析)2007
- Author(s)
  吉川圭介、北芳博、島田厚良、細川昌則、清水孝雄
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 老化促進モデルマウスの海馬の興奮毒性に対する脆弱性とミクログリアの応答異常2007
- Author(s)
  島田厚良、石井さなえ、吉川圭介、千葉陽一、河村則子、熊谷直子、細川昌則
- Organizer
  第48回日本神経病理学会総会・学術研究会
- Place of Presentation
  東京
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 加齢性神経変性モデルSenescence-accelerated mice SAMP10におけるエイコサノイドの網羅的定量解析2007
- Author(s)
  吉川圭介, 北芳博, 島田厚良, 石井さなえ, 古川絢子, 河村則子, 千葉陽一, 熊谷直子, 清水孝雄, 細川昌則
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 老化促進モデルマウスの海馬の興奮毒性に対する脆弱性とミクログリアの応答異常2007
- Author(s)
  島田厚良, 石井さなえ, 吉川圭介, 千葉陽一, 河村則子, 熊谷直子, 細川昌則
- Organizer
  第48回日本神経病理学会総会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10マウス大脳皮質におけるプロテオグリカン関連エピトープ6B4め発現低下2007
- Author(s)
  松井ふみ子、斉藤優子、河村則子、千葉陽一、熊谷直子、石井さなえ、吉川圭介、島田厚良、前田信明、大平敦彦、細川昌則
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10を用いた加齢性中枢神経変性における神経炎症の関わりについて-proinflammatory cytokines の加齢変化と脳萎縮-2007
- Author(s)
  熊谷直子, 千葉陽一, 細野正道, 藤井庄人, 河村則子, 吉川圭介, 石井さなえ, 古川絢子, 島田厚良, 細川昌則
- Organizer
  第22回老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  酒田市
- Year and Date
  2007-07-27
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 老化促進モデルマウスの海馬の興奮毒性に対する脆弱性とミクログリアの応答異常2007
- Author(s)
  石井さなえ、島田厚良、千葉陽一、吉川圭介、古川絢子、河村則子、熊谷直子、細川昌則
- Organizer
  第12回グリア研究会
- Place of Presentation
  名古屋
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 神経変性モデルSAMP10マウスにおけるミクログリア退行変性の早期出現2007
- Author(s)
  石井さなえ, 島田厚良, 吉川圭介, 千葉陽一, 河村則子, 古川絢子, 細川昌則
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜市
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10マウス大脳皮質におけるプロテオグリカン関連エピトープ6B4の発現低下2007
- Author(s)
  松井ふみ子, 齊藤優子, 河村則子, 慶野裕美, 千葉陽一, 熊谷直子, 石井さなえ, 吉川圭介, 島田厚良, 前田信明, 大平敦彦, 細川昌則
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜市
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 海馬興奮毒性における二相性プロスタノイド産生(脂質の網羅的質量分析)2007
- Author(s)
  吉川圭介, 北芳博, 島田厚良, 細川昌則, 清水孝雄
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜市
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 加齢に伴うミクログリアの退行性変化2007
- Author(s)
  石井さなえ、島田厚良、吉川圭企、千葉陽一、河村則子、古川絢子、細川昌則
- Organizer
  第22回老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  酒田
- Year and Date
  2007-07-27
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] プロテアソーム活性阻害とユビキチン化封入体形成がSAMP10 マウス由来培養神経細胞に与える影響2007
- Author(s)
  千葉陽一, 島田厚良, 熊谷直子, 河村則子, 吉川圭介, 石井さなえ, 古川絢子, 細川昌則
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜市
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 老化促進モデルマウスの海馬の興奮毒性に対する脆弱性とミクログリアの応答異常2007
- Author(s)
  石井さなえ, 島田厚良, 千葉陽一, 吉川圭介, 古川絢子, 河村則子, 熊谷直子, 細川昌則
- Organizer
  第12回グリア研究会
- Place of Presentation
  名古屋市
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 老化促進モデルマウスSAMP1系統における被毛と皮膚の加齢変化2007
- Author(s)
  佐倉正明, 平出孝枝, 河村則子, 千葉陽一, 熊谷直子, 吉川圭介, 石井さなえ, 古川絢子, 島田厚良, 細川昌則
- Organizer
  第22回老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  酒田市
- Year and Date
  2007-07-27
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 神経変性モデルSAMP10マウスの海馬の興奮毒性に対する脆弱性とミクログリアの応答異常2007
- Author(s)
  島田厚良, 石井さなえ, 吉川圭介, 千葉陽一, 河村則子, 古川絢子, 細川昌則
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜市
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] プロテアソーム活性阻害とユビキチン化封入体がSAMP10マウス由来培養細胞神経細胞に与える影響2007
- Author(s)
  千葉陽一、島田厚良、熊谷直子、河村則子、吉川圭介、石井さなえ、古川絢子、細川昌則
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10由来初代培養神経細胞を用いたユビキチン化封入体形成の病的意義2007
- Author(s)
  千葉陽一, 島田厚良, 熊谷直子, 河村則子, 吉川圭介, 石井さなえ, 古川絢子, 細川昌則
- Organizer
  第22回老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  酒田市
- Year and Date
  2007-07-27
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] 加齢に伴うミクログリアの退行性変化2007
- Author(s)
  石井さなえ, 島田厚良, 千葉陽一, 吉川圭介, 古川絢子, 河村則子, 熊谷直子, 細川昌則
- Organizer
  第22回老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  酒田市
- Year and Date
  2007-07-27
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10由来初代培養細胞を用いたユビキチン化封入体系性の病的意義2007
- Author(s)
  千葉陽一、島田厚良、熊谷直子、河村則子、吉川圭介、石井さなえ、古川絢子、細川昌則
- Organizer
  第22回老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  酒田
- Year and Date
  2007-07-27
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] SAMP10マウスにおけるユビキチン化封入体形成の病的意義に関する培養系を用いた解析2007
- Author(s)
  千葉陽一, 島田厚良, 熊谷直子, 河村則子, 吉川圭介, 石井さなえ, 細川昌則
- Organizer
  第48回日本神経病理学会総会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-19790766
[Presentation] Prostaglandin F2a FP receptor inhibitor suppress demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model
- Author(s)
  Yoshikawa K, Iwasa K, Yamamoto S, Maruyama K
- Organizer
  NEUROSCIENCE
- Place of Presentation
  ワシントンDC、アメリカ合衆国
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25670781
[Presentation] Establishment of a non-transgenic mouse model of neurodegenerative diseases with accelerated phosphorylation of endogenous tau
- Author(s)
  Sosuke Yagishita, Seiya Suzuki, Takeo Awaji, Keisuke Yoshikawa, Masahiko Suzuki, Akira Hirasawa, Kei Maruyama
- Organizer
  第12回 RCGM フロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学日高キャンパス（埼玉県日高市）
- Year and Date
  2014-10-31 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] Prostaglandin F2FP receptor inhibitor reduces demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model
- Author(s)
  岩佐健介、山本梓司、高橋茉莉香、鈴木星也、柳下聡介、淡路健雄、丸山敬、吉川圭介
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction
- Author(s)
  Yamamoto S, Gotoh M, Kawamura Y, Yamashina K, Yagishita S, Awaji T, Tanaka M, Maruyama K, Murakami-Murofushi K, Yoshikawa K
- Organizer
  Phospholipase and other lipid mediators 2015
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction
- Author(s)
  Yamamoto S, Gotoh M, Kawamura Y, Yamashina K, Yagishita S, Awaji T, Tanaka M, Maruyama K, Murakami-Murofushi K, Yoshikawa K
- Organizer
  European committee for treatment and research in Multiple Sclerosis
- Place of Presentation
  バルセロナ、スペイン
- Year and Date
  2015-10-07 – 2015-10-10
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] Prostaglandin F2a FP receptor inhibitor suppress demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model
- Author(s)
  Yoshikawa K, Iwasa K, Yamamoto S, Maruyama K
- Organizer
  NEUROSCIENCE
- Place of Presentation
  ワシントンDC、アメリカ合衆国
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] Prostaglandin F2α FP receptor inhibitor reduce demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model
- Author(s)
  Yoshikawa K, Iwasa K, Yamamoto S, Maruyama K
- Organizer
  NEUROSCIENCE
- Place of Presentation
  ワシントンDC（アメリカ）
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26670126
[Presentation] Prostaglandin F2α FP receptor inhibitor reduce demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse mode
- Author(s)
  Iwasa K, Yamamoto S, Takahashi M, Suzuki S, Awaji T, Maruyama K, Yoshikawa K
- Organizer
  Phospholipase and other lipid mediators 2015
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-26670126
[Presentation] Prostaglandin F2α FP receptor inhibitor reduce demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model
- Author(s)
  Iwasa K, Yamamoto S, Takahashi M, Suzuki S, Yagishita S, Awaji T, Maruyama K, Yoshikawa K
- Organizer
  Phospholipase and other lipid mediators 2015
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-25670781
[Presentation] Prostaglandin F2α FP receptor inhibitor reduce demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model
- Author(s)
  Iwasa K, Yamamoto S, Takahashi M, Suzuki S, Yagishita S, Awaji T, Maruyama K, Yoshikawa K
- Organizer
  Phospholipase and other lipid mediators 2015
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-25870677
[Presentation] Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction
- Author(s)
  Yamamoto S, Gotoh M, Kawamura Y, Yamashina K, Yagishita S, Awaji T, Tanaka M, Maruyama K, Murakami-Murofushi K, Yoshikawa K
- Organizer
  Phospholipase and other lipid mediators 2015
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-25670781
[Presentation] Prostaglandin F2a FP receptor inhibitor suppress demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model.
- Author(s)
  Yoshikawa K, Iwasa K, Yamamoto S, Maruyama K.
- Organizer
  Neuroscience 2014
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction
- Author(s)
  Yamamoto S, Gotoh M, Kawamura Y, Yamashina K, Yagishita S, Awaji T, Tanaka M, Maruyama K, Murakami-Murofushi K, Yoshikawa K
- Organizer
  PLM2015 (Phospholipase and other lipid mediators)
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-25460341
[Presentation] Prostaglandin F2α FP receptor inhibitor reduce demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model
- Author(s)
  Iwasa K, Yamamoto S, Takahashi M, Suzuki S, Yagishita S, Awaji T, Maruyama K, Yoshikawa K
- Organizer
  PLM2015 (Phospholipase and other lipid mediators)
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-25460341

1. Iwasa Kensuke (00623703)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
2. Maruyama Kei (30211577)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
3. YAMAMOTO Shinji (70823318)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
4. Kondo Ryuichiro (80091370)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Kuniyoshi Shimizu (20346836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. NOMURA Ryota (90437385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 柳下聡介 (30585592)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
8. 柳下楠 (70799189)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TANAKA Motomu (70197482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. SHIMIZU Takao (80127092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. KITA Yoshihiro (20401028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Suzuki Masahiko (40105888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. NAKAO Takehira (90522300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. ISHIKAWA Masaki (10758684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. ADACHI Takahiro (60387610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 淡路健雄 (60297546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
17. 五十嵐美樹 (70340172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. TAKAHASHI Marika

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. HARUTA asuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 平澤明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshikawa Keisuke 吉川 圭介

YOSHIKAWA Keisuke 吉川 圭介

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PGD2ミクログリア神経炎症サイクルを制御する腸脳相関の神経変性疾患治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the gut-brain interaction starting from the lipid sensor in the gastrointestinal tract and its application to the treatment of neurological disordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Treatment strategy for hypoxic-ischemic encephalopathy by regulation of prostaglandins bioactivitiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inhibition of prostanoid productions as prophylaxis and therapeutic strategy for treatment of long lasting neuronal death in excitotoxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Long term administration of loquat leaves and their major component, ursolic acid, attenuated endogenous amyloid-b burden and memory impairment2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dietary oleic acid contributes to the regulation of food intake through the synthesis of intestinal oleoylethanolamide2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Microglial depletion exacerbates axonal damage and motor dysfunction in mice with cuprizone-induced demyelination2023

Yoshikawa Keisuke 吉川圭介

YOSHIKAWA Keisuke 吉川圭介