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Aoki Hiroshi  青木 博史

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AOKI Hiroshi  青木 博史

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Researcher Number 10440067
External Links
Affiliation (Current) 2025: 日本獣医生命科学大学, 獣医学部, 教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 日本獣医生命科学大学, 獣医学部, 教授
2015 – 2021: 日本獣医生命科学大学, 獣医学部, 准教授
2012: 日本獣医生命科学大学, 獣医学部, 准教授
2007 – 2011: 日本獣医生命科学大学, 獣医学部, 講師
Review Section/Research Field
Principal Investigator
Veterinary medical science / Basic veterinary science/Basic zootechnical science
Except Principal Investigator
Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Applied veterinary science
Keywords
Principal Investigator
ペスチウイルス / 自然免疫 / 牛ウイルス性下痢ウイルス / 病原ウイルス / IFNAR1ノックアウト細胞 / 内因性干渉 / ウイルス間相互反応 / 自然免疫制御 / 同種干渉 / 準種 / 持続感染 / 干渉現象 … More
Except Principal Investigator
… More 病原性 / 豚熱ウイルス / 豚コレラウイルス / Erns蛋白質 / 持続感染 / 非定型豚ペスチウイルス / 機能解明 / 準種 / ウイルス因子 / 分子疫学 / 新規ウイルス / 種間伝播 / 遺伝子組み換え / 新種ウイルス / メタゲノム解析 / ウイルス / 下痢症 / 家畜 / 宿主 / ペスチウイルス / 自然免疫 Less
  • Research Projects

    (6 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (9 People)
  •  Functional analysis of Erns protein involved in persistent infection of classical swine fever virus and atypical porcine pestivirus

    • Principal Investigator
      迫田 義博
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Hokkaido University
  •  Function analysis of the viral factors which regulate the pathogenicity of classical swine fever virus

    • Principal Investigator
      SAKODA Yoshihiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Hokkaido University
  •  Molecular analysis of infectious properties caused by coexistence of pestiviruses with different innate immune regulation within viral strainsPrincipal Investigator

    • Principal Investigator
      Aoki Hiroshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Nippon Veterinary and Life Science University
  •  Research of viral community for unexplained livestock diarrhea and discovery of novel gastrointestinal viruses

    • Principal Investigator
      NAGAI Makoto
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Ishikawa Prefectural University
      Tokyo University of Agriculture and Technology
  •  Studies on virus-host interaction and innate immunity involved in the persistent infection of bovine viral diarrhea virusPrincipal Investigator

    • Principal Investigator
      AOKI Hiroshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Nippon Veterinary and Life Science University
  •  Molecular basis of pathogenicity of classical swine fever virus -Mechanism of down regulation of innate immunity in the cells and pigs infected with classical swine fever virus-

    • Principal Investigator
      SAKODA Yoshihiro
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      Hokkaido University

All 2023 2022 2021 2020 2019 2017 2016 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] Isolation and artificial production of atypical porcine pestivirus, using the swine-kidney-derived cell line SK-L2023

    • Author(s)
      Shiokawa Mai、Morita Yui、Nagai Makoto、Haritani Makoto、Aoki Hiroshi
    • Journal Title

      Archives of Virology

      Volume: 168 Issue: 12

    • DOI

      10.1007/s00705-023-05919-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K23769
  • [Journal Article] Establishment of guinea pig kidney cell lines with potential application in the production of a classical swine fever live GPE<sup>−</sup> vaccine2023

    • Author(s)
      SHIODA Moe、SHIOKAWA Mai、AOKI Hiroshi
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 85 Issue: 3 Pages: 308-317

    • DOI

      10.1292/jvms.22-0385

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K23769
  • [Journal Article] Effect of the Timing of Vaccination in Pregnant Sows and Colostral Restriction for Neonatal Piglets on the Level of Transmission of Maternal Antibodies for Classical Swine Fever Vaccine to Suckling Piglets2022

    • Author(s)
      NOGUCHI Michiko、SUZUKI Takehito、KOSOGABE Hitomi、SASAKI Yosuke、AOKI Hiroshi、NAGAI Makoto
    • Journal Title

      Journal of the Japan Veterinary Medical Association

      Volume: 75 Issue: 9 Pages: e180-e185

    • DOI

      10.12935/jvma.75.e180

    • ISSN
      0446-6454, 2186-0211
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K23769
  • [Journal Article] 先天性振戦(ダンス病)と非定型豚ペスチウイルス2022

    • Author(s)
      塩川舞、青木博史
    • Journal Title

      All about SWINE

      Volume: 61 Pages: 12-19

    • Data Source
      KAKENHI-PROJECT-23K23769
  • [Journal Article] Bovine endometrium-derived cultured cells are suitable for lipofection2021

    • Author(s)
      Shiokawa Mai、Miura Ryotaro、Okubo Aki、Hagita Yujiro、Yoshimura Itaru、Aoki Hiroshi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 16207-16207

    • DOI

      10.1038/s41598-021-95848-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03115
  • [Journal Article] Detection and genetic analysis of a novel atypical porcine pestivirus from piglets with congenital tremor in Japan2021

    • Author(s)
      Kasahara‐Kamiie Miwako、Kagawa Mitsuo、Shiokawa Mai、Sunaga Fujiko、Fukase Yuka、Aihara Naoyuki、Shiga Takanori、Kamiie Junichi、Aoki Hiroshi、Nagai Makoto
    • Journal Title

      Transboundary and Emerging Diseases

      Volume: 印刷中 Issue: 4 Pages: 1-9

    • DOI

      10.1111/tbed.14149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K05977, KAKENHI-PROJECT-19H03115
  • [Journal Article] Development of a one-run real-time PCR detection system for pathogens associated with porcine respiratory diseases2020

    • Author(s)
      SUNAGA Fujiko、TSUCHIAKA Shinobu、KISHIMOTO Mai、AOKI Hiroshi、KAKINOKI Mari、KURE Katsumasa、OKUMURA Hanako、OKUMURA Maho、OKUMURA Atsushi、NAGAI Makoto、OMATSU Tsutomu、MIZUTANI Tetsuya
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 82 Issue: 2 Pages: 217-223

    • DOI

      10.1292/jvms.19-0063

    • NAID

      130007799384

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03115
  • [Journal Article] END-phenomenon negative bovine viral diarrhea virus that induces the host's innate immune response supports propagation of BVDVs with different immunological properties2019

    • Author(s)
      Shiokawa Mai、Omatsu Tsutomu、Katayama Yukie、Nishine Kaoru、Fujimoto Yuri、Uchiyama Shiori、Kameyama Ken-ichiro、Nagai Makoto、Mizutani Tetsuya、Sakoda Yoshihiro、Fukusho Akio、Aoki Hiroshi
    • Journal Title

      Virology

      Volume: 538 Pages: 97-110

    • DOI

      10.1016/j.virol.2019.09.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03115
  • [Journal Article] Diversity in VP3, NSP3, and NSP4 of rotavirus B detected from Japanese cattle.2017

    • Author(s)
      Hayashi-Miyamoto M, Murakami T, Minami-Fukuda F, Tsuchiaka S, Kishimoto M, Sano K, Naoi Y, Asano K, Ichimaru T, Haga K, Omatsu T, Katayama Y, Oba M, Aoki H, Shirai J, Ishida M, Katayama K, Mizutani T, Nagai M.
    • Journal Title

      Infection, genetics and evolution

      Volume: 49 Pages: 97-103

    • DOI

      10.1016/j.meegid.2017.01.003

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07718
  • [Journal Article] Whole genome analysis of porcine astroviruses detected in Japanese pigs reveals genetic diversity and possible intra-genotypic recombination.2017

    • Author(s)
      Ito M, Kuroda M, Masuda T, Akagami M, Haga K, Tsuchiaka S, Kishimoto M, Naoi Y, Sano K, Omatsu T, Katayama Y, Oba M, Aoki H, Ichimaru T, Mukono I, Ouchi Y, Yamasato H, Shirai J, Katayama K, Mizutani T, Nagai M.
    • Journal Title

      Infection, genetics and evolution

      Volume: 50 Pages: 38-48

    • DOI

      10.1016/j.meegid.2017.02.008

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07718
  • [Journal Article] Complete sequencing of bovine viral diarrhea virus 1 subgenotype 1n and 1o.2016

    • Author(s)
      Sato A, Tateishi K, Shinohara M, Naoi Y, Shiokawa M, Aoki H, Ohmori K, Mizutani T, Shirai J, Nagai M.
    • Journal Title

      Genome announcements

      Volume: 18 Issue: 1 Pages: 1-1

    • DOI

      10.1128/genomea.01744-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07718
  • [Journal Article] Whole genome analysis of Japanese bovine toroviruses reveals natural recombination between porcine and bovine toroviruses.2016

    • Author(s)
      Ito M, Tsuchiaka S, Naoi Y, Otomaru K, Sato M, Masuda T, Haga K, Oka T, Yamasato H, Omatsu T, Sugimura S, Aoki H, Furuya T, Katayama Y, Oba M, Shirai J, Katayama K, Mizutani T, Nagai M.
    • Journal Title

      Infection, genetics and evolution

      Volume: 38 Pages: 90-95

    • DOI

      10.1016/j.meegid.2015.12.013

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07718
  • [Journal Article] Characterization and phylogenetic analysis of a novel picornavirus from swine feces in Japan.2016

    • Author(s)
      Naoi Y, Kishimoto M, Masuda T, Ito M, Tsuchiaka S, Sano K, Yamasato H, Omatsu T, Aoki H, Furuya T, Katayama Y, Oba M, Okada T, Shirai J, Mizutani T, Nagai M.
    • Journal Title

      Archives of virology

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07718
  • [Journal Article] Biologicalproperties of bovine viral diarrhea virusquasispecies detected in RK-13 cell line2013

    • Author(s)
      Mahmod MUHSEN, Hiroshi AOKI, HidetoshiIKEDA, Akio Fukusho
    • Journal Title

      Archives of Virology

      Volume: 158(2) Issue: 4 Pages: 753-763

    • DOI

      10.1007/s00705-012-1538-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22780265
  • [Journal Article] Methods to select suitable fetal bovine serum for use in quality of control assays for the detection of adventitious viruses from biological products2011

    • Author(s)
      Kozasa T, Aoki H, et al
    • Journal Title

      Biologicals

      Volume: 39 Issue: 4 Pages: 242-248

    • DOI

      10.1016/j.biologicals.2011.06.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22780265
  • [Journal Article] 豚コレラ清浄性維持確認のための診断技術2009

    • Author(s)
      青木博史
    • Journal Title

      養豚の友 479

      Pages: 24-29

    • Data Source
      KAKENHI-PROJECT-19380170
  • [Journal Article] 日本における豚コレラの撲滅達成と今後2008

    • Author(s)
      青木博史
    • Journal Title

      獣医疫学雑誌 12(2)

      Pages: 120-124

    • NAID

      130000340450

    • Data Source
      KAKENHI-PROJECT-19380170
  • [Journal Article] 豚コレラ清浄性維持確認に求められる豚コレラ診断法について2008

    • Author(s)
      青木博史
    • Journal Title

      家畜衛生雑誌 34(3)

      Pages: 109-114

    • Data Source
      KAKENHI-PROJECT-19380170
  • [Presentation] 非定型豚ペスチウイルスの分離とイノシシから検出されたウイルスの遺伝学的解析2023

    • Author(s)
      塩川舞,長井誠,青木博史
    • Organizer
      第166回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K23769
  • [Presentation] 非定型豚ペスチウイルスの分離と作出方法2021

    • Author(s)
      塩川舞、森田結衣、長井誠、青木博史
    • Organizer
      第27回トガ・フラビ・ペスチウイルス研究会
    • Data Source
      KAKENHI-PROJECT-19H03115
  • [Presentation] リポフェクション効率の高い牛由来培養細胞の作出とウイルス感染症研究への応用2021

    • Author(s)
      塩川舞、三浦亮太郎、大久保阿輝、萩田裕二郎、青木博史
    • Organizer
      第164回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03115
  • [Presentation] 牛ウイルス性下痢ウイルス同種干渉における重感染ウイルスの複製と自然免疫応答2012

    • Author(s)
      青木博史
    • Organizer
      第154回日本獣医学会学術集会
    • Place of Presentation
      岩手大学
    • Year and Date
      2012-09-15
    • Data Source
      KAKENHI-PROJECT-22780265
  • [Presentation] 牛ウイルス性下痢ウイルス準種-野外流行株に含まれるEND現象陰性ウイルスの検出と分布-2012

    • Author(s)
      西根薫、青木博史、迫田義博、福所秋雄
    • Organizer
      第32回獣医疫学会学術集会
    • Place of Presentation
      大宮ソニックシティ
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-22780265
  • [Presentation] 牛ウイルス性下痢ウイルスの宿主~牛以外の動物における感染と実態~2011

    • Author(s)
      青木博史
    • Organizer
      第151回日本獣医学会学術集会
    • Place of Presentation
      東京農工大学
    • Year and Date
      2011-03-30
    • Data Source
      KAKENHI-PROJECT-22780265
  • [Presentation] END陰性の牛ウイルス性下痢ウイルス感染及び同種ウイルス干渉時の自然免疫関連mRNA解析2011

    • Author(s)
      青木博史、西根薫、榎戸眞徒、塩川舞、福所秋雄
    • Organizer
      第18回トガ・フラビ・ペスチウイルス研究会
    • Place of Presentation
      国立感染症研究所
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-22780265
  • [Presentation] 牛ウイルス性下痢ウイルス野外株内の準種含有量及び疾病との関連性2011

    • Author(s)
      西根薫、青木博史、迫田義博、福所秋雄
    • Organizer
      第152回日本獣医学会学術集会
    • Place of Presentation
      大阪府立大学
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-22780265
  • [Presentation] END陰性の牛ウイルス性下痢ウイルス感染及び同種ウイルス干渉時の自然免疫関連mRNA解析2011

    • Author(s)
      青木博史
    • Organizer
      第18回トガ・フラビ・ペスチウイルス研究会
    • Place of Presentation
      国立感染症研究所初感染
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-22780265
  • [Presentation] 生物性状の異なる牛ウイルス性下痢ウイルスを用いた自然免疫関連mRNAの解析2011

    • Author(s)
      青木博史
    • Organizer
      第152回日本獣医学会学術集会
    • Place of Presentation
      大阪府立大学
    • Year and Date
      2011-09-20
    • Data Source
      KAKENHI-PROJECT-22780265
  • [Presentation] 細胞病原性牛ウイルス性下痢ウイルスNose株に含まれる非細胞病原性準種の遺伝子構造解析2010

    • Author(s)
      青木博史
    • Organizer
      第149回日本獣医学会
    • Place of Presentation
      日本獣医生命科学大学、東京
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-19380170
  • [Presentation] 細胞病原性牛ウイルス性下痢ウイルスNose株に含まれる費細胞病原性準種の遺伝子構造解析2010

    • Author(s)
      青木博史
    • Organizer
      第149回日本獣医学会
    • Place of Presentation
      日本獣医生命科学大学、東京
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-19380170
  • [Presentation] 牛ウイルス性下痢ウイルスの生物現象の差によるゲノム塩基配列の相違2007

    • Author(s)
      小佐々隆志、青木博史、野田紗知子、関口秀人、福所秋雄、中村成幸
    • Organizer
      第55回日本ウイルス学会学術集会
    • Place of Presentation
      札幌コンベンションセンター、札幌
    • Data Source
      KAKENHI-PROJECT-19380170
  • [Presentation] 牛ウイルス性下痢ウイルス同種干渉における重感染ウイルスの複製と自然免疫応答

    • Author(s)
      青木博史
    • Organizer
      日本獣医学会
    • Place of Presentation
      岩手大学
    • Data Source
      KAKENHI-PROJECT-22780265
  • 1.  SAKODA Yoshihiro (40333637)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 2.  NAGAI Makoto (10540669)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 3.  MIZITANI Tetsuya (70281681)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 4.  SHIRAI Junsuke (00355182)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  五十嵐 学 (10374240)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Ito Mika
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  Masuda Tsuneyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  Akagami Masataka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  Niira Kazutaka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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