ISHITSUKA Kenji 石塚賢治

… Alternative Names

Ishitsuka Kenji 石塚賢治

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Researcher Number	10441742
Other IDs
Affiliation (Current)	2025: 鹿児島大学, 医歯学域医学系, 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 鹿児島大学, 医歯学域医学系, 教授 2015: 鹿児島大学, 医学部, 教授 2013 – 2014: 福岡大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Hematology Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Human pathology / Basic Section 49020:Human pathology-related
Keywords	Principal Investigator 新規治療 / 前臨床試験 / Bcl-2関連蛋白 / 成人T細胞白血病・リンパ腫 / Mcl-1 / Bcl-2 / 抗アポトーシス蛋白 / ATL Except Principal Investigator HTLV-1 / ATLL … More / C-MYC / in situ hybridization / T細胞 / ホジキンリンパ腫 / PLCG1 / ATL / 結晶構造解析 / PROTAC / CARD11 / 成人T細胞白血病リンパ腫 / ヒト免疫不全ウイルス 1 型 / 生体内ゲノム編集 / 成人T細胞白血病 / HTLV-1 bZIP factor / ゲノム編集 / bZIP factor / アデノウイルスベクター / CRISPR/Cas9 / HBZ / ｍｉｃｒｏＲＮＡ / ＦＢＸＷ７ / Ｃ－ＭＹＣ / T/NK細胞リンパ腫 / NK cell lymphoma / T cell lymphoma / 相関する因子 / MIB1 / 予後因子 / TILs / PD-L1 / PD1 / CMYC / 予後 / T細胞リンパ腫 / Bcl2 / c-Myc / c-Met / Ｔ細胞リンパ腫 / 腸管症 / 消化管 / BCL2 / IEL / FISH / C-MET / T-cell lymphoma / enteropathy Less

新規病態：HTLV-1陽性HRS細胞を伴う成人T細胞白血病/リンパ腫の統合的解析
- Principal Investigator
  
  加留部謙之輔
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Nagoya University
Establishment of a novel drug discovery platform for adult T-cell leukemia/lymphoma using PROTAC technology
- Principal Investigator
  
  Yoshimitsu Makoto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kagoshima University
生体内ゲノム編集を利用したHTLV-1を標的にする新規抗ウイルス療法
- Principal Investigator
  
  鈴木紳介
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kagoshima University
Influence of CMYC and its ubiquitin ligase FBXW7 in T/NK cell lymphoma
- Principal Investigator
  
  Takeshita Morishige
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Fukuoka University
Development of novel treatment strategies for adult T-cell leukemia/lymphoma by targeting anti-apoptotic proteins.Principal Investigator
- Principal Investigator
  
  Ishitsuka Kenji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kagoshima University
Detailed clinicopathological characteristics and possible lymphomagenesis of type II intestinal enteropathy-associated T-cell lymphoma
- Principal Investigator
  
  Takeshita Morishige
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Fukuoka University

All 2022 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Gamma-secretase inhibitor does not induce cytotoxicity in adult T-cell leukemia cell lines despite NOTCH1 expression.2022
- Author(s)
  Suzuki S, Hourai S, Uozumi K, Uchida Y, Yoshimitsu M, Miho H, Arima N, Ueno SI, Ishitsuka K.
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1
- DOI
  10.1186/s12885-022-10003-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08870
[Journal Article] Clinical and cytopathological characteristics of HTLV-1(+) Hodgkin lymphoma.2020
- Author(s)
  Kobata K, Kimura S, Mihashi Y, Iwasaki H, Nonaka S, Matsumoto S, Takamatsu Y, Choi I, Kawauchi S, Ishitsuka K, Takeshita M.
- Journal Title
  
  Cancer Medicine
  
  Volume: 9 Issue: 16 Pages: 5788-5797
- DOI
  10.1002/cam4.3139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08732
[Journal Article] Treatment of aggressive adult T-cell leukemia/lymphoma: a retrospective study in a hospital located in HTLV-1 highly endemic area.2020
- Author(s)
  Nakamura D, Yoshimitsu M, Tabuchi T, Arima N, Hayashida M, Inoue H, Matsushita K, Matsumoto T, Arima N, Ishitsuka K.
- Journal Title
  
  Int J Hematol.
  
  Volume: 111 Issue: 2 Pages: 234-240
- DOI
  10.1007/s12185-019-02769-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09933
[Journal Article] A survivin-responsive, conditionally replicating adenovirus induces potent cytocidal effects in adult T-cell leukemia/lymphoma2019
- Author(s)
  Suzuki Shinsuke、Kofune Hiroki、Uozumi Kimiharu、Yoshimitsu Makoto、Arima Naomichi、Ishitsuka Kenji、Ueno Shin-ichi、Kosai Ken-ichiro
- Journal Title
  
  BMC Cancer
  
  Volume: 19 Issue: 1 Pages: 516-516
- DOI
  10.1186/s12885-019-5730-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08870, KAKENHI-PROJECT-17H04315
[Journal Article] C-MYC and its main ubiquitin ligase, FBXW7, influence cell proliferation and prognosis in adult T-cell leukemia/lymphoma2017
- Author(s)
  Y. Mihashi, M. Mizoguchi, Y. Takamatsu, K. Ishitsuka,H. Iwasaki, M. Koga, K. Urabe, S. Momosaki, T. Sakata, F. Kiyomi, and M. Takeshita
- Journal Title
  
  Am J Surg Pathol
  
  Volume: 41 Pages: 1139-1149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08732
[Journal Article] High expression of intestinal homing receptor CD103 in adult T-cell leukemia/lymphoma, similar to 2 other CD8+ T-cell lymphomas.2016
- Author(s)
  Ishibashi H, Nimura S, Ishitsuka K, Mihashi Y, Mizoguchi M, Nakamura S, Okamura S, Momosaki S, Aoyagi K, Sakisaka S, Takeshita M.
- Journal Title
  
  Am J Surg Pathol
  
  Volume: 40 Issue: 4 Pages: 462-470
- DOI
  10.1097/pas.0000000000000597
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460418, KAKENHI-PROJECT-25460444
[Presentation] ASCO/JCA/JSMO/JSCO Joint Symposium: Cancer Prevention－Our Final Goal－　ウイルスとがん ―HTLV-1とATL―2018
- Author(s)
  石塚　賢治
- Organizer
  第56回日本癌治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09933

1. Takeshita Morishige (90171636)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. Yoshimitsu Makoto (70404530)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. NAKAMURA Shotaro (10243932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 高松泰 (50320297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 鈴木紳介 (20437974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 上野真一 (40322317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 魚住公治 (90253864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 加留部謙之輔 (20508577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 加藤光次 (20571764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 福島卓也 (40336160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 佐藤賢文 (70402807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 下田和哉 (90311844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ISHITSUKA Kenji 石塚 賢治

Ishitsuka Kenji 石塚 賢治

Research Projects

Research Products

Co-Researchers

新規病態：HTLV-1陽性HRS細胞を伴う成人T細胞白血病/リンパ腫の統合的解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a novel drug discovery platform for adult T-cell leukemia/lymphoma using PROTAC technology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生体内ゲノム編集を利用したHTLV-1を標的にする新規抗ウイルス療法

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Influence of CMYC and its ubiquitin ligase FBXW7 in T/NK cell lymphoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel treatment strategies for adult T-cell leukemia/lymphoma by targeting anti-apoptotic proteins.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detailed clinicopathological characteristics and possible lymphomagenesis of type II intestinal enteropathy-associated T-cell lymphoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gamma-secretase inhibitor does not induce cytotoxicity in adult T-cell leukemia cell lines despite NOTCH1 expression.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical and cytopathological characteristics of HTLV-1(+) Hodgkin lymphoma.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Treatment of aggressive adult T-cell leukemia/lymphoma: a retrospective study in a hospital located in HTLV-1 highly endemic area.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A survivin-responsive, conditionally replicating adenovirus induces potent cytocidal effects in adult T-cell leukemia/lymphoma2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] C-MYC and its main ubiquitin ligase, FBXW7, influence cell proliferation and prognosis in adult T-cell leukemia/lymphoma2017

Author(s)

Journal Title

Data Source

[Journal Article] High expression of intestinal homing receptor CD103 in adult T-cell leukemia/lymphoma, similar to 2 other CD8+ T-cell lymphomas.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] ASCO/JCA/JSMO/JSCO Joint Symposium: Cancer Prevention－Our Final Goal－ ウイルスとがん ―HTLV-1とATL―2018

Author(s)

Organizer

Data Source

ISHITSUKA Kenji 石塚賢治

Ishitsuka Kenji 石塚賢治

[Presentation] ASCO/JCA/JSMO/JSCO Joint Symposium: Cancer Prevention－Our Final Goal－　ウイルスとがん ―HTLV-1とATL―2018