Umeda Kaori 梅田香織

… Alternative Names

ENDO-UMEDA Kaori 梅田香織

UMEDA Kaori 梅田香織

遠藤香織

ENDO Kaori 遠藤香織

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Researcher Number	10445744
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2025: 日本大学, 医学部, 助教 2020 – 2023: 日本大学, 医学部, 助教 2017: 日本大学, 医学部, 助教 2012 – 2016: 日本大学, 医学部, 助手 2010: 日本大学, 医学部, 専修研究員
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Pathological medical chemistry Except Principal Investigator Pathological medical chemistry / Biological Sciences
Keywords	Principal Investigator 核内受容体 / LXR / 肝臓 / 炎症 / liver X receptor / 肝炎 / iNKT細胞 / NKT細胞 / マクロファージ / NASH … More / コレステロール / シングルセル解析 / 非アルコール性脂肪肝炎 / 肝臓X受容体 / Kupffer細胞 / 腫瘍免疫 / がん / サイトカイン / 抗腫瘍活性 / 胸腺 / コレステロール代謝 / 脂質代謝 … More Except Principal Investigator ビタミンD受容体 / クッパ－細胞 / NK細胞 / NKT細胞 / マクロファージ / インターロイキン6 / リトコール酸 / 胆汁酸 / 炎症 / 胆汁鬱滞 / 自然免疫 / クッパ-細胞 / 急性肝障害 / ビタミンD誘導体 / サイトカイン / 肝臓 / 肝障害 / ビリルビン / ノックアウトマウス / 転写因子 / 転写調節 / 強心ステロイド / β-カテニン / CYP1 / ビタミン / 脂質代謝 / 時計遺伝子 / 重力 / ビタミンD / コファクター / LXR / CYP1A1 / ダイオキシン受容体 / モーダルシフト / セルセンサー / 代謝 / 発現制御 / 脂質 / 蛋白質 / 遺伝子 / 核内受容体 Less

MASHから肝細胞癌への進展過程におけるコレステロール代謝調節因子LXRの影響Principal Investigator
- Principal Investigator
  
  梅田香織
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Nihon University
Role of liver X receptor on the regulation of hepatic immune cell population and function in nonalcoholic steatohepatitisPrincipal Investigator
- Principal Investigator
  
  ENDO-UMEDA Kaori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Nihon University
Effects of liver X receptor on regulation of NKT cell-induced inflammation and antitumor activityPrincipal Investigator
- Principal Investigator
  
  ENDO-UMEDA Kaori
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nihon University
Effects of LXR on innate immune responses in hepatic mononuclear cellsPrincipal Investigator
- Principal Investigator
  
  ENDO-UMEDA Kaori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nihon University
Regulation of intestinal and hepatic immunity and metabolism by vitamin D receptor
- Principal Investigator
  
  MAKISHIMA Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nihon University
Regulation of inflammation and metabolism by vitamin Dreceptor in hepatic immune cells
- Principal Investigator
  
  MAKISHIMA Makoto
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nihon University
Dynamic regulation of metabolite-sensing nuclear receptors
- Principal Investigator
  
  MAKISHIMA Makoto
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nihon University

All 2023 2022 2021 2018 2017 2016 2015 2014 2012 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Liver X receptors regulate natural killer T cell population and antitumor activity in the liver of mice2021
- Author(s)
  Endo-Umeda Kaori、Nakashima Hiroyuki、Uno Shigeyuki、Toyoshima Shota、Umeda Naoki、Komine-Aizawa Shihoko、Seki Shuhji、Makishima Makoto
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 22595-22595
- DOI
  10.1038/s41598-021-02062-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06862
[Journal Article] Dysregulation of Kupffer Cells/Macrophages and Natural Killer T Cells in Steatohepatitis in LXRα Knockout Male Mice2018
- Author(s)
  Endo-Umeda Kaori、Nakashima Hiroyuki、Umeda Naoki、Seki Shuhji、Makishima Makoto
- Journal Title
  
  Endocrinology
  
  Volume: 159 Issue: 3 Pages: 1419-1432
- DOI
  10.1210/en.2017-03141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08751, KAKENHI-PROJECT-16K19061
[Journal Article] Differential expression and function of alternative splicing variants of human liver X receptor alpha2012
- Author(s)
  Endo-Umeda, K., et al.
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 81 Issue: 6 Pages: 800-810
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077005
[Journal Article] Suppression of beta-catenin signaling by liver X receptor ligands.2009
- Author(s)
  Uno S, Endo K, Jeong Y, Kawana K, Miyachi H, Hashimoto Y, Makishima M
- Journal Title
  
  Biochem Pharmacol 77
  
  Pages: 186-195
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077005
[Journal Article] The aryl hydrocarbon receptor activator benzo[a]pyrene enhances vitamin D3 catabolism in macrophages.2009
- Author(s)
  Matsunawa M, Amano Y, Endo K, Uno S, Sakaki T, Yamada S, Makishima M.
- Journal Title
  
  Toxicol Sci 10
  
  Pages: 50-58
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077005
[Journal Article] Suppression of beta-catenin signaling by liver X receptor ligands.2009
- Author(s)
  Uno S, Endo K, Jeong Y, Kawana K, Miyachi H, Hashimoto Y, Makishima M.
- Journal Title
  
  Biochem Pharmacol 77
  
  Pages: 186-195
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077005
[Journal Article] Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene2008
- Author(s)
  Endo, K.
- Journal Title
  
  Toxicology and Applied Pharmacology 230
  
  Pages: 135-143
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077005
[Journal Article] Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene.2008
- Author(s)
  Endo K, Uno S, Seki T, Ariga T, Kusumi Y, Mitsumata M, Yamada S, Makishima M.
- Journal Title
  
  Toxicol Appl Pharmacol 230
  
  Pages: 135-143
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077005
[Journal Article] The aryl hydrocarbon receptor activator benzo [a] pyrene enhances vitamin D3 catabolism in macrophages.
- Author(s)
  Matsunawa M, Amano Y, Endo K, Uno S, Sakaki T, Yamada S, Makishima M
- Journal Title
  
  Toxicol Sci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077005
[Presentation] 非アルコール性脂肪肝炎における核内受容体LXRによる肝臓免疫細胞制御機構の解明2023
- Author(s)
  梅田　香織
- Organizer
  2023年度「先進ゲノム支援」拡大班会議
- Data Source
  KAKENHI-PROJECT-21K06862
[Presentation] 核内受容体liver X receptorによるナチュラルキラーT細胞分布及び肝臓抗腫瘍活性制御2022
- Author(s)
  梅田（遠藤）香織, 中島弘幸, 宇野茂之, 豊島翔太, 梅田直, 相澤（小峯）志保子, 関修司, 槇島誠
- Organizer
  日本レチノイド研究会第33回学術集会
- Data Source
  KAKENHI-PROJECT-21K06862
[Presentation] 核内受容体liver X receptorによるナチュラルキラーT細胞分布及び肝臓抗腫瘍活性制御2021
- Author(s)
  梅田（遠藤）香織, 中島弘幸, 宇野茂之, 豊島翔太, 梅田直, 相澤（小峯）志保子, 関修司, 槇島誠
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06862
[Presentation] Liver X receptors regulate natural killer T cell population and hepatic antitumor activity in mice2021
- Author(s)
  Kaori Endo-Umeda, Hiroyuki Nakashima, Shota Toyoshima, Shihoko Komine-Aizawa, Shuhji Seki, Makoto Makishima
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06862
[Presentation] 肝臓免疫細胞における核内受容体LXRの自然免疫調節作用2017
- Author(s)
  梅田（遠藤）香織, 中島弘幸, 梅田直, 関修司, 槇島誠
- Organizer
  日本レチノイド研究会第28回学術集会
- Data Source
  KAKENHI-PROJECT-16K19061
[Presentation] 核内受容体LXRαの肝免疫細胞における脂質代謝及び炎症調節メカニズムの解明2016
- Author(s)
  梅田（遠藤）香織、中島弘幸、関修司、槇島誠
- Organizer
  第2回Neo Vitamin D Workshop学術集会
- Place of Presentation
  TKPガーデンシティ品川（東京都）
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-16K19061
[Presentation] 肝免疫細胞における自然免疫調節機構に対する核内受容体LXRの影響2015
- Author(s)
  梅田（遠藤）香織、中島弘幸、関修司、槇島誠
- Organizer
  第1回Neo Vitamin D Workshop学術集会
- Place of Presentation
  大津プリンスホテル（滋賀県大津市）
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-25860248
[Presentation] Liver X receptor modulates innate immune response in hepatic mononuclear cells2014
- Author(s)
  Kaori Endo-Umeda, Hiroyuki Nakashima, Shuhji Seki and Makoto Makishima
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-25860248
[Presentation] 肝臓免疫系細胞の自然免疫調節機構に対する核内受容体LXRの役割2014
- Author(s)
  梅田（遠藤）香織
- Organizer
  細胞センサーの分子機構・相互関連・ネットワーク研究会
- Place of Presentation
  生理学研究所（愛知県岡崎市）
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-25860248
[Presentation] 高脂肪高コレステロール付加肝障害モデルにおける核内受容体LXRの脂質代謝及び自然免疫調節機構の解明2014
- Author(s)
  梅田（遠藤）香織、中島弘幸、関　修司、槇島　誠
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-25860248
[Presentation] 7-デヒドロコレステロール誘導体による選択的LXR作用機構2009
- Author(s)
  遠藤香織
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-18077005
[Presentation] 新規ヒトLXRαスプライシング変異体の作用機序の解明2009
- Author(s)
  遠藤香織
- Organizer
  第2回博多シンポジウム「内・外環境と生物応答」
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PLANNED-18077005
[Presentation] ヒトLXRαスプライシング変異体の作用機序の解明2008
- Author(s)
  遠藤香織
- Organizer
  第31回日本分子生物学会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-18077005
[Presentation] ベンゾ[a]ピレンのDNA付加体形成とダイオキシン受容体の転写活性化におけるCYP1ファミリー酵素の役割2007
- Author(s)
  遠藤香織
- Organizer
  第30回日本分子生物学会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-18077005
[Presentation] 肝免疫系細胞における自然免疫調節機構に対する核内受容体LXR の影響
- Author(s)
  梅田（遠藤）香織
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25860248

1. MAKISHIMA Makoto (70346146)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. ISHIZAWA Michiyasu (30646542)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. YAMADA Sachiko (10014078)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. NISHIDA Shigeru (90211458)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SEKI Shuji (80531392)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. UNO Shigeyuki (90307851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. CHOI Mihwa (30571012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. CHO Yoshitake (70468742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAKURAI Kenichi (20366602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAWANA Katsuyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. AMANO Yusuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. OGURA Michitaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OGEKI Jun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. UMEDA Naoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中島弘幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 中島正裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Umeda Kaori 梅田 香織

ENDO-UMEDA Kaori 梅田 香織

UMEDA Kaori 梅田 香織

遠藤 香織

ENDO Kaori 遠藤 香織

Research Projects

Research Products

Co-Researchers

MASHから肝細胞癌への進展過程におけるコレステロール代謝調節因子LXRの影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of liver X receptor on the regulation of hepatic immune cell population and function in nonalcoholic steatohepatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of liver X receptor on regulation of NKT cell-induced inflammation and antitumor activityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of LXR on innate immune responses in hepatic mononuclear cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of intestinal and hepatic immunity and metabolism by vitamin D receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of inflammation and metabolism by vitamin Dreceptor in hepatic immune cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dynamic regulation of metabolite-sensing nuclear receptors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Liver X receptors regulate natural killer T cell population and antitumor activity in the liver of mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dysregulation of Kupffer Cells/Macrophages and Natural Killer T Cells in Steatohepatitis in LXRα Knockout Male Mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential expression and function of alternative splicing variants of human liver X receptor alpha2012

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of beta-catenin signaling by liver X receptor ligands.2009

Author(s)

Journal Title

Data Source

[Journal Article] The aryl hydrocarbon receptor activator benzo[a]pyrene enhances vitamin D3 catabolism in macrophages.2009

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of beta-catenin signaling by liver X receptor ligands.2009

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene2008

Author(s)

Journal Title

Data Source

Umeda Kaori 梅田香織

ENDO-UMEDA Kaori 梅田香織

UMEDA Kaori 梅田香織

遠藤香織

ENDO Kaori 遠藤香織