Honda Ikuko 本田郁子 (小山郁子)

… Alternative Names

小山郁子

本田郁子ホンダイクコ(コヤマイクコ)

小山郁子

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Researcher Number	10447948
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院医学系研究科(医学部), 准教授
Affiliation (based on the past Project Information) *help	2025: 東京大学, 大学院医学系研究科(医学部), 准教授 2022 – 2023: 東京大学, 大学院医学系研究科(医学部), 准教授 2018 – 2019: 東京大学, 大学院医学系研究科(医学部), 特任講師 2017: 東京大学, 大学院医学系研究科(医学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 44010:Cell biology-related / Biological Sciences / Structural biochemistry
Keywords	Principal Investigator リソソーム / オートファゴソーム / オートファジー / オートリソソーム / ATG8 / 繋留因子 / 膜融合 / 1粒子解析 / 多変量解析 / 粒子解析 … More / エンドソーム / エンドサイトーシス / オルガネラ / 生体膜 / 光学顕微鏡 / 細胞 / 膜分裂 / ESCRTタンパク質 / 数理モデル / 3D-CLEM / membrane fission / ESCRT複合体タンパク質 Less

オートファゴソーム内膜の分解におけるリソソームとの繋留因子の役割Principal Investigator
- Principal Investigator
  
  本田郁子 (小山郁子)
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  The University of Tokyo
オルガネラ粒子マルチパラメーター計測で展開する細胞内オルガネラ遷移Principal Investigator
- Principal Investigator
  
  本田郁子 (小山郁子)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  The University of Tokyo
オートリソソーム形成における脂質修飾型ATG8の機能解明Principal Investigator
- Principal Investigator
  
  本田郁子 (小山郁子)
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Molecular mechanism of autophagosome membrane closurePrincipal Investigator
- Principal Investigator
  
  Honda Ikuko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2019 2018 2017

All Journal Article Presentation

[Journal Article] Experimental determination and mathematical modeling of standard shapes of forming autophagosomes2024
- Author(s)
  Sakai Yuji、Takahashi Satoru、Koyama-Honda Ikuko、Saito Chieko、Mizushima Noboru
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41467-023-44442-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05715, KAKENHI-PUBLICLY-22H04635
[Journal Article] Organelle landscape analysis using a multi-parametric particle-based method2023
- Author(s)
  Yoshitaka Kurikawa, Ikuko Koyama-Honda, Keiko Igarashi, Norito Tamura, Seiichi Koike, Noboru Mizushima
- Journal Title
  
  bioRxiv
  
  Volume: 09.25. Pages: 559448-559448
- DOI
  10.1101/2023.09.25.559448
- Open Access
- Data Source
  KAKENHI-PROJECT-22K06217
[Journal Article] Quantitative 3D correlative light and electron microscopy of organelle association during autophagy2022
- Author(s)
  Takahashi Satoru、Saito Chieko、Koyama-Honda Ikuko、Mizushima Noboru
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 47 Issue: 2 Pages: 89-99
- DOI
  10.1247/csf.22071
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04919, KAKENHI-PUBLICLY-22H04635
[Journal Article] Transient visit of STX17 (syntaxin 17) to autophagosomes2022
- Author(s)
  Koyama-Honda Ikuko、Mizushima Noboru
- Journal Title
  
  Autophagy
  
  Volume: 18 Issue: 6 Pages: 1213-1215
- DOI
  10.1080/15548627.2022.2079337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04919, KAKENHI-PUBLICLY-22H04635
[Journal Article] Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets2017
- Author(s)
  Tamura Norito、Nishimura Taki、Sakamaki Yuriko、Koyama-Honda Ikuko、Yamamoto Hayashi、Mizushima Noboru
- Journal Title
  
  FEBS Letters
  
  Volume: 591 Issue: 23 Pages: 3819-3830
- DOI
  10.1002/1873-3468.12901
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07302, KAKENHI-PLANNED-25111005, KAKENHI-PROJECT-17H03670, KAKENHI-PROJECT-16K14720
[Journal Article] ATG conjugation-dependent degradation of the inner autophagosomal membrane is a key step for autophagosome maturation2017
- Author(s)
  Koyama-Honda Ikuko、Tsuboyama Kotaro、Mizushima Noboru
- Journal Title
  
  Autophagy
  
  Volume: 13 Issue: 7 Pages: 1252-1253
- DOI
  10.1080/15548627.2017.1319041
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07302, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111005
[Journal Article] オートファジーを蛍光で観る2017
- Author(s)
  本田郁子、水島昇
- Journal Title
  
  医学の歩み
  
  Volume: 262 Pages: 538-543
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] 高分解能・マルチパラメータ解析をめざした細胞内小器官研究法2023
- Author(s)
  小山-本田郁子
- Organizer
  日本顕微鏡学会第46回関東支部講演会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06217
[Presentation] Organelle landscape analysis using a multi-parametric particle-based method2023
- Author(s)
  Ikuko Koyama-Honda, Yoshitaka Kurikawa, Noboru Mizushima
- Organizer
  EMBO The Company of Biologists Workshop on Membrane shaping and remodeling by proteins
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06217
[Presentation] オルガネラダイナミクスを"解きほぐす“：マルチカラー単粒子解析法の開発2023
- Author(s)
  栗川義俊、小山-本田郁子、小池誠一、田村律人、水島昇
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06217
[Presentation] オートファジー実験デザインのいろは～そこにオートファジーはあるのか？ないのか？～2023
- Author(s)
  小山ー本田郁子
- Organizer
  日本顕微鏡学会第78回学術講演会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] Quantitative 3D correlative light and electron microscopy of autophagosome-organelle contacts and autophagosomal contents2023
- Author(s)
  Satoru Takahashi, Chieko Saito, Ikuko Koyama-Honda, Noboru Mizushima
- Organizer
  Ubiquitin & Friends Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] マルチパラメータ単粒子解析法を用いたオルガネラランドスケープの解析2023
- Author(s)
  栗川義俊、小山-本田郁子、小池誠一、田村律人、水島昇
- Organizer
  第15回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-22K06217
[Presentation] A quantitative method for multiparametric analysis of organellar particles2023
- Author(s)
  Ikuko Koyama-Honda, Yoshitaka Kurikawa, Noboru Mizushima
- Organizer
  Gordon Research Conference on Molecular Membrane Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06217
[Presentation] アレイトモグラフィー法をオートファジー研究に応用する2023
- Author(s)
  小山‐本田郁子、髙橋暁、境祐二、齊藤知恵子、水島昇
- Organizer
  第129回日本解剖学会総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] マクロオートファジーにおける細胞質ゾーニング2023
- Author(s)
  小山－本田郁子、境祐二、高橋暁、齊藤知恵子、立川正志、水島昇
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] 細胞内オルガネラ多色単粒子計測法の開発2023
- Author(s)
  小山-本田郁子、栗川義峻、水島昇
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06217
[Presentation] オートファゴソーム内膜の分解におけるATG8と繋留因子の役割2023
- Author(s)
  小山-本田郁子、高橋暁、水島昇
- Organizer
  第15回オートファジー研究会
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] Characterization of the highly-curved rim of forming autophagosomes2022
- Author(s)
  Ikuko Koyama-Honda, Masashi Tachikawa, Yuji Sakai, Noboru Mizushima
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] オートリソソーム形成における脂質修飾型ATG8の機能解明2022
- Author(s)
  小山ー本田郁子
- Organizer
  新学術領域「マルチモードオートファジー」第４回班会議
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] Morphological and molecular analysis on the relationship between autophagosome-lysosome fusion and autophagosomal inner membrane degradation2022
- Author(s)
  Satoru Takahashi, Willa Wen-You Yim, Chieko Saito, Ikuko Koyama-Honda, Noboru Mizushima
- Organizer
  The 10th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] 3D-CLEM using array tomography for quantification in autophagy research2022
- Author(s)
  Satoru Takahashi, Willa Wen-You Yim, Chieko Saito, Yuji Sakai, Hayashi Yamamoto, Ikuko Koyama-Honda, and Noboru Mizushima
- Organizer
  日本顕微鏡学会第78回学術講演会
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] Characterization of the highly-curved rim of phagophore during autophagosome formation2022
- Author(s)
  Ikuko Koyama-Honda, Masashi Tachikawa, Yuji Sakai, Noboru Mizushima
- Organizer
  The 10th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] 細胞小器官の多パラメータ粒子解析法の開発2022
- Author(s)
  栗川義峻, 小山-本田郁子, 小池誠一, 田村律人, 水島昇
- Organizer
  第21回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06217
[Presentation] 細胞小器官の多パラメータ粒子解析法の開発2022
- Author(s)
  栗川義峻, 小池誠一, 田村律人, 水島昇, 小山-本田郁子
- Organizer
  第45回日本分子生物学会大会
- Data Source
  KAKENHI-PROJECT-22K06217
[Presentation] Integrating the molecular, mechanistic and physiological diversity of autophagy2022
- Author(s)
  Ikuko Koyama-Honda, Masashi Tachikawa, Yuji Sakai, Noboru Mizushima
- Organizer
  EMBO Workshop, Integrating the molecular, mechanistic and physiological diversity of autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04635
[Presentation] Visualization of autophagosome maturation2019
- Author(s)
  Ikuko Koyama-Honda
- Organizer
  The OIST minisymposium - The 16th International Membrane Research Forum
- Invited
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] Autophagosome membrane morphology2019
- Author(s)
  Ikuko Koyama-Honda, Masashi Tachikawa, Yuji Sakai, Noboru Mizushima
- Organizer
  A3 Conference in China
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] Autophagosome formation: live-cell imaging and theoretical modeling2019
- Author(s)
  Ikuko Koyama-Honda, Masashi Tachikawa, Yuji Sakai, Noboru Mizushima
- Organizer
  EMBO Workshop on Membrane Shaping and Remodeling by Proteins
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] Theoretical and cell biological studies on phagophore morphology2019
- Author(s)
  Ikuko Koyama-Honda, Masashi Tachikawa, Yuji Sakai, Noboru Mizushima
- Organizer
  The 9th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] オートファゴソーム形成過程における膜曲率安定化因子と膜供給: 物理モデルと生細胞観察による研究2018
- Author(s)
  小山―本田郁子、立川正志、境祐二、田村律人、望月敦史、水島昇
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] オートファゴソーム形成過程の形態変化2018
- Author(s)
  小山ー本田郁子、立川正志、境祐二、田村律人、坂巻純一、望月敦史、水島昇
- Organizer
  第１１回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] オートファゴソーム形成の生細胞観察と物理モデル構築2017
- Author(s)
  小山-本田郁子, 立川正志, 境祐二, 田村律人, 望月敦史, 水島昇
- Organizer
  2017年度生命科学系学会合同大会 ConBio2017
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] オートファゴソームの形成から成熟までの形態変化を追う2017
- Author(s)
  本田郁子
- Organizer
  第14回AMO討論会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] ESCRTタンパク質はオートファゴソーム膜閉鎖過程に機能する2017
- Author(s)
  守田啓悟, 小山-本田郁子, 山下義博, 上野敏秀, 森田英嗣, 間野博行, 水島昇
- Organizer
  2017年度生命科学系学会合同大会 ConBio2017
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] Autophagosomal closure is mediated by the ESCRT machinery.2017
- Author(s)
  Keigo Morita, Ikuko Koyama-Honda, Yoshihiro Yamashita, Toshihide Ueno, Eiji Morita, Hiroyuki Mano, Noboru Mizushima
- Organizer
  ASCB|EMBO 2017 Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] リソソームによるオートファゴソーム膜分解のin vitro再構成2017
- Author(s)
  Willa Yim, 森下英晃、小山-本田郁子、水島昇
- Organizer
  2017年度生命科学系学会合同大会 ConBio2017
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] 非選択的オートファジー活性評価のための新規プローブ2017
- Author(s)
  森航、森下英晃、小山-本田郁子、水島昇
- Organizer
  2017年度生命科学系学会合同大会 ConBio2017
- Data Source
  KAKENHI-PROJECT-17K07302
[Presentation] 見てわかるオートファジー2017
- Author(s)
  小山-本田郁子
- Organizer
  第5回光塾
- Invited
- Data Source
  KAKENHI-PROJECT-17K07302

1. 境祐二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 水島昇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Honda Ikuko 本田 郁子 (小山 郁子)

小山 郁子

本田 郁子 ホンダ イクコ(コヤマイクコ)

小山郁子

Research Projects

Research Products

Co-Researchers

オートファゴソーム内膜の分解におけるリソソームとの繋留因子の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

オルガネラ粒子マルチパラメーター計測で展開する細胞内オルガネラ遷移Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

オートリソソーム形成における脂質修飾型ATG8の機能解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of autophagosome membrane closurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Experimental determination and mathematical modeling of standard shapes of forming autophagosomes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Organelle landscape analysis using a multi-parametric particle-based method2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantitative 3D correlative light and electron microscopy of organelle association during autophagy2022

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Transient visit of STX17 (syntaxin 17) to autophagosomes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ATG conjugation-dependent degradation of the inner autophagosomal membrane is a key step for autophagosome maturation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] オートファジーを蛍光で観る2017

Author(s)

Journal Title

Data Source

[Presentation] 高分解能・マルチパラメータ解析をめざした細胞内小器官研究法2023

Author(s)

Organizer

Data Source

[Presentation] Organelle landscape analysis using a multi-parametric particle-based method2023

Author(s)

Organizer

Data Source

[Presentation] オルガネラダイナミクスを"解きほぐす“：マルチカラー単粒子解析法の開発2023

Author(s)

Organizer

Data Source

[Presentation] オートファジー実験デザインのいろは～そこにオートファジーはあるのか？ないのか？～2023

Honda Ikuko 本田郁子 (小山郁子)

小山郁子

本田郁子ホンダイクコ(コヤマイクコ)