Watanabe Mitsuhiro 渡辺光博

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WATANABE Mitsuhiro 渡辺光博

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Researcher Number	10450842
Affiliation (Current)	2025: 慶應義塾大学, 政策・メディア研究科(藤沢), 教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 慶應義塾大学, 政策・メディア研究科(藤沢), 教授 2012 – 2014: 慶應義塾大学, 政策・メディア研究科, 教授 2011: 慶應義塾大学, 医学部, 特任准教授 2008 – 2010: Keio University, 医学部, 准教授
Review Section/Research Field	Principal Investigator Applied biochemistry / Gastroenterology Except Principal Investigator Basic Section 59020:Sports sciences-related / Basic Section 59040:Nutrition science and health science-related / Metabolomics / Endocrinology / Medical pharmacy / Biological Sciences
Keywords	Principal Investigator 胆汁酸 / 代謝 / 糖尿病 / 消化器 / 肥満 / 腸内細菌 / 発現解析 / ACC / アセチルCoAカルボキシラーゼ / 脂肪酸合成 … More / 肝臓 / 脂質代謝 / メタボリックシンドローム / オミックス解析 / エネルギー代謝 / 生活習慣病 / 核内受容体 … More Except Principal Investigator 腸内細菌 / 胆汁酸 / 認知機能 / 運動 / タンパク質 / 栄養バランス / メタボリックシンドローム / 個別化医療 / 個人差 / バイオマーカー / 薬剤反応性 / イリノテカン / NADH/NAD比 / IEGs / 乳酸 / Sirtuin 1 / eNAMPT / NAD / 加齢 / 炭水化物 / ミトコンドリア / 代謝 / 栄養素バランス / 次世代 / 腸管環境 / 腸管免疫 / 肥満症 / 糖尿病 / エネルギー代謝異常症 / FoxO1 / Fox01 / iPS細胞 / FOXO1 / 心血管ホルモン / 細胞代謝 / 抗加齢医学 / 内分泌学 / オキサリプラチン / SELDI-TOF MS / プロテオーム / 抗癌剤 / 核酸代謝 / 5-FU / SN-38 / CE-TOFMS / メタボローム Less

Whether blood lactate increased via high-intense exercise contributes to the improvement of cognitive function due to high-intensity exercise or not?
- Principal Investigator
  
  三上俊夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Nippon Medical School
腸内細菌・胆汁酸・ミトコンドリアに着目した最適な栄養バランス解明
- Principal Investigator
  
  横山葉子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Keio University
Does exercise prevent cognitive decline by suppressing the age-related decrease in hippocampal NAD+?
- Principal Investigator
  
  三上俊夫
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Nippon Medical School
Research on Next Generation Inheritance with a Focus on Bile Acid-Gut Microbiota Interactions by Nutrient Balance and Quality
- Principal Investigator
  
  YOKOYAMA Yoko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Keio University
Promotion of personalized medicine for lifestyle-related diseases by revealing bile acids, microbiota and cell signaling interactionPrincipal Investigator
- Principal Investigator
  
  WATANABE Mitsuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
The therapy for metabolic disorder by immune-regulation of gut microbiome.
- Principal Investigator
  
  IRIE JUNICHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Keio University
The expression of beta-oxidation adjustment key factor ACC2 elucidation which aimed at the metabolic syndrome new therapyPrincipal Investigator
- Principal Investigator
  
  WATANABE Mitsuhiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Keio University
Regulation of cell-metabolism by cardiovascular hormones and the comprehensive application to metabolic syndrome.
- Principal Investigator
  
  ITOH Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Keio University
がんのメタボローム解析に基づく抗がん剤反応性予測の新戦略
- Principal Investigator
  
  TANIGAWARA Yusuke
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Proteomic analysis for elucidation of individual differences in chemotherapeutic response and for biomarker development
- Principal Investigator
  
  TANIGAWARA Yusuke
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Keio University
Approach to metabolic syndrome by analysing the energy metabolism homeostasisPrincipal Investigator
- Principal Investigator
  
  WATANABE Mitsuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Keio University

[Book] あなたの健康寿命はもっとのばせる！2017
- Author(s)
  渡辺光博
- Total Pages
  223
- Publisher
  日本文芸社
- Data Source
  KAKENHI-PROJECT-16H05292
[Book] 糖尿病に効く！胆汁酸健康法2014
- Author(s)
  渡辺光博
- Total Pages
  192
- Publisher
  洋泉社
- Data Source
  KAKENHI-PROJECT-23580139
[Book] くらしと胆汁酸胆汁酸と代謝調節. たんじゅうさん(1348-0189) 2013 12 巻2 号2013
- Author(s)
  渡辺光博
- Publisher
  アークメディア社
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 「糖尿病に効く!胆汁酸健康法」2013
- Author(s)
  渡辺光博
- Publisher
  洋泉社
- Data Source
  KAKENHI-PROJECT-23580139
[Book] アンチエイジングを目指した胆汁酸による代謝調節. アンチ・エイジング医学(1880-1579)9 巻2013
- Author(s)
  渡辺光博
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 【肥満症の病態と治療に関する最近の知見-肥満症医療の新しい地平】胆汁酸とエネルギー代謝調節. カレントテラピー 30 巻 6 号2012
- Author(s)
  渡辺光博
- Publisher
  株式会社ライフメディコム
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 第15 章レスベラトロールの脂肪動員への作用. 書籍「レスベラトロールの基礎と応用」2012
- Author(s)
  杉崎太一、渡辺光博
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 【栄養素の受容・情報伝達と代謝制御】胆汁酸の受容体と代謝制御. 内分泌・糖尿病・代謝内科 2012 vol.34 no.42012
- Author(s)
  杉崎太一、渡辺光博
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 【消化管とエネルギー代謝】胆汁酸による代謝調節. Medical Science Digest 2011 : 37 巻2011
- Author(s)
  渡辺光博. 伊藤裕
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 【次世代の2 型糖尿病薬物治療】胆汁酸吸着レジンの血糖降下作用(colestimide、colesevelam など). Mebio 2011 : 28 巻2011
- Author(s)
  森本耕吉. 渡辺光博
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 【腎における内分泌関連トピックス】胆汁酸のホルモン様作用メタボリックシンドロームへの関与. 腎と透析 2011 : 71 巻2011
- Author(s)
  森本耕吉. 渡辺光博
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 【核内受容体とアディポサイエンス】LXR、FXR、PXR、TR とアディポサイエンスコレステロール関連化合物がつなぐ核内受容体群. Adiposcience 2011 : 7 巻2011
- Author(s)
  森本耕吉, 渡辺光博
- Publisher
  フジメディカル出版
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 【メタボリックシンドロームと臓器連関】胆汁酸による代謝臓器間連関. Medical Science Digest 2011 : 37 巻2011
- Author(s)
  渡辺光博
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 胆汁酸代謝を介した肥満及び糖・脂質代謝異常への介入 farnesoid X receptor、TGR5/M-Bar の知見から。糖尿病2011 : 54 巻2011
- Author(s)
  渡辺光博
- Publisher
  日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-23580139
[Book] 胆汁酸による糖・エネルギー代謝2010
- Author(s)
  渡辺光博
- Publisher
  中外医薬社
- Data Source
  KAKENHI-PROJECT-20580103
[Book] 胆汁酸による甲状腺ホルモン代謝調節2010
- Author(s)
  渡辺光博
- Publisher
  医学の世界社
- Data Source
  KAKENHI-PROJECT-20580103
[Book] 肥満と脂肪エネルギー代謝2008
- Author(s)
  渡辺光博
- Publisher
  建帛社
- Data Source
  KAKENHI-PROJECT-20580103
[Book] 肥満と脂肪エネルギー代謝2008
- Author(s)
  渡辺光博
- Publisher
  建パク社
- Data Source
  KAKENHI-PROJECT-20580103
[Journal Article] Sodium ferrous citrate and 5‐aminolevulinic acid improve type 2 diabetes by maintaining muscle and mitochondrial health2023
- Author(s)
  Kitamura Naho、Zhang Shiyang、Morel Jean‐David、Nagano Utana、Taworntawat Tanon、Hosoda Shotaro、Nakamura Anna、Ogawa Yoko、Benegiamo Giorgia、Auwerx Johan、Tsubota Kazuo、Yokoyama Yoko、Watanabe Mitsuhiro
- Journal Title
  
  Obesity
  
  Volume: 31 Issue: 4 Pages: 1038-1049
- DOI
  10.1002/oby.23705
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11709, KAKENHI-PROJECT-19K11751
[Journal Article] Metabolic Effects of Bee Larva-Derived Protein in Mice: Assessment of an Alternative Protein Source2021
- Author(s)
  Yokoyama Yoko、Shinohara Kawori、Kitamura Naho、Nakamura Anna、Onoue Ai、Tanaka Kazuki、Hirayama Akiyoshi、Aw Wanping、Nakamura Shigeru、Ogawa Yoko、Fukuda Shinji、Tsubota Kazuo、Watanabe Mitsuhiro
- Journal Title
  
  Foods
  
  Volume: 10 Issue: 11 Pages: 2642-2642
- DOI
  10.3390/foods10112642
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21J12844, KAKENHI-PROJECT-19K11751
[Journal Article] 治療標的としての胆汁酸シグナル2017
- Author(s)
  北村奈穂, 渡辺光博．
- Journal Title
  
  実験医学
  
  Volume: 35 Pages: 258-265
- Data Source
  KAKENHI-PROJECT-16H05292
[Journal Article] 胆汁酸代謝調節と糖尿病治療2017
- Author(s)
  川島えり, 渡辺光博.
- Journal Title
  
  プラクティス
  
  Volume: 34 Pages: 372-379
- Data Source
  KAKENHI-PROJECT-16H05292
[Journal Article] Bile acid binding resin improves hepatic insulin sensitivity by reducing cholesterol but not triglyceride levels in the liver.2015
- Author(s)
  Hirotsune Tagawa, Junichiro Irie, Arata Itoh, Yukie Kusumoto, Mari Kato, Nana Kobayashi, Kumiko Tanaka, Rieko Morinaga, Masataka Fujita, Yuya Nakajima, Kohkichi Morimoto, Taichi Sugizaki, Yoshinaga Kawano, Satoru Yamada, Toshihide Kawai, Mitsuhiro Watanabe, Hiroshi Itoh
- Journal Title
  
  Diabetes Research and Clinical Practice
  
  Volume: 印刷中 Issue: 1 Pages: 85-94
- DOI
  10.1016/j.diabres.2015.04.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591342
[Journal Article] Vitamin D and energy homeostasis--of mice and men.2014
- Author(s)
  Bouillon R, Carmeliet G, Lieben L, Watanabe M, Perino A, Auwerx J, Schoonjans K, Verstuyf A.
- Journal Title
  
  Nat Rev Endocrinol
  
  Volume: 10 Issue: 2 Pages: 79-87
- DOI
  10.1038/nrendo.2013.226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] The Niemann-Pick C1 Like 1 (NPC1L1) Inhibitor Ezetimibe Improves Metabolic Disease Via Decreased Liver X Receptor (LXR) Activity in Liver of Obese Male Mice.2014
- Author(s)
  Taichi Sugizaki, Mitsuhiro Watanabe, Yasushi Horai, Nao Kaneko-Iwasaki, Eri Arita, Teruo Miyazaki, Kohkichi Morimoto, Akira Honda, Junichiro Irie, Hiroshi Itoh
- Journal Title
  
  Endocrinology
  
  Volume: 155 Issue: 8 Pages: 2810-2819
- DOI
  10.1210/en.2013-2143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591342
[Journal Article] 胆汁酸吸着レジンの抗肥満効果における腸内細菌、腸内環境の意義　腸管分泌Fiafの新規肥満形成機構の解明.2013
- Author(s)
  楠本幸恵, 入江潤一郎, 田川裕恒, 伊藤新, 加藤麻里, 小林奈奈, 田中久美子, 森永理恵子, 藤田真隆, 山田悟, 河合俊英, 尾池雄一, 渡辺光博, 伊藤裕.
- Journal Title
  
  日本肥満症治療学会学術集会プログラム・抄録集31回
  
  Volume: 抄録集 Pages: 117-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] くらしと胆汁酸胆　　汁酸と代謝調節.2013
- Author(s)
  渡辺光博
- Journal Title
  
  たんじゅうさん
  
  Volume: １２ Pages: 20-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] 「冬痩せの教室～腹の周りの肉は本当に落ちないのか？」2013
- Author(s)
  渡辺光博
- Journal Title
  
  UOMO
  
  Volume: 10 Pages: 237-237
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Calorie restriction (CR) and CR mimetics for the prevention and treatment of age-related eye disorders2013
- Author(s)
  Kawashima M, Ozawa Y, Shinmura K, Inaba T, Nakamura S, Kawakita T, Watanabe M, Tsubota K.
- Journal Title
  
  Exp Gerontol
  
  Volume: Apr 12(pii: S0531-5565(13)00100-9)
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Calorie restriction (CR) and CR mimetics for the prevention and treatment of age-related eye disorders.2013
- Author(s)
  Kawashima M, Ozawa Y, Shinmura K, Inaba T, Nakamura S, Kawakita T, Watanabe M, Tsubota K.
- Journal Title
  
  Exp Gerontol
  
  Volume: 48 Issue: 10 Pages: 1096-1100
- DOI
  10.1016/j.exger.2013.04.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139, KAKENHI-PROJECT-24592647, KAKENHI-PROJECT-25293356
[Journal Article] Light-dark condition regulates sirtuin mRNA levels in the retina2013
- Author(s)
  Ban N, Ozawa Y, Inaba T, Miyake S, Watanabe M, Shinmura K, Tsubota K.
- Journal Title
  
  Exp Gerontol.
  
  Volume: 48 Issue: 11 Pages: 1212-1217
- DOI
  10.1016/j.exger.2013.04.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139, KAKENHI-PROJECT-24592647
[Journal Article] マウス網膜における明暗条件によるSirtuin遺伝子発現の日内変化.2013
- Author(s)
  伴紀充, 小沢洋子, 稲葉隆明, 三宅誠司, 渡辺光博, 新村健, 坪田一男.
- Journal Title
  
  日本抗加齢医学会総会プログラム・抄録集13回
  
  Volume: 6 Pages: 187-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Vitamin D and energy homeostasis-of mice and men2013
- Author(s)
  Bouillon R, Carmeliet G, Lieben L, Watanabe M, Perino A, Auwerx J, Schoonjans K, Verstuyf A.
- Journal Title
  
  Nature Rev Endocrinol
  
  Volume: Nov 19
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Cysteine sulfinic acid decarboxylase regulation: A role for farnesoid X receptor and small heterodimer partner in murine hepatic taurine metabolism.2013
- Author(s)
  Kerr TA, Matsumoto Y, Matsumoto H, Xie Y, Hirschberger LL, Stipanuk MH, Anakk S, Moore DD, Watanabe M, Kennedy S, Davidson NO.
- Journal Title
  
  Hepatol Res
  
  Volume: Epub ahead of print Issue: 10
- DOI
  10.1111/hepr.12230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] 肝臓の抗加齢を求めて　エネルギー代謝の問題点とその解決に向けて胆汁酸による肝脂質代謝とエネルギー代謝調節2013
- Author(s)
  渡辺光博
- Journal Title
  
  日本抗加齢医学会総会プログラム・抄録集13回
  
  Volume: 6 Pages: 112-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Tysnd1 deficiency in mice interferes with the peroxisomal localization of PTS2 enzymes, causing lipid metabolic abnormalities and male infertility2013
- Author(s)
  Mizuno Y, Ninomiya Y, Nakachi Y, Iseki M, Iwasa H, Akita M, Tsukui T, Shimozawa N, Ito C, Toshimori K, Nishimukai M, Hara H, Maeba R, Okazaki T, Alodaib AN, Al Amoudi M, Jacob M, Alkuraya FS, Horai Y, Watanabe M, Motegi H, Wakana S, Noda T, Kurochkin IV, Mizuno Y, Schönbach C, Okazaki Y.
- Journal Title
  
  PLoS Genet
  
  Volume: 9(2)
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Tysndl Deficiency in Mice Interferes with the Peroxisomal Localization of PTS2 Enzymes, Causing Lipid Metabolic Abnormalities and Male Infertility2013
- Author(s)
  Yumi Mizuno, et al.
- Journal Title
  
  PLoS Genetics.
  
  Volume: 9 Issue: 2 Pages: e1003286-e1003286
- DOI
  10.1371/journal.pgen.1003286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590344, KAKENHI-PROJECT-22390033, KAKENHI-PROJECT-23580139, KAKENHI-PROJECT-23659090, KAKENHI-PUBLICLY-24112706, KAKENHI-PROJECT-24390261, KAKENHI-PROJECT-24592441, KAKENHI-PROJECT-25293041, KAKENHI-PROJECT-25670087
[Journal Article] Bile Acids Increase Levels of microRNAs 221 and 222, Leading to Degradation of CDX2 During Esophageal Carcinogenesis2013
- Author(s)
  Matsuzaki J, Suzuki H, Tsugawa H, Watanabe M, Hossain S, Arai E, Saito Y, Sekine S, Akaike T, Kanai Y, Mukaisho KI, Auwerx J, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: Aug 8(pii:S0016-5085(13)01154-2)
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] アンチエイジングを目指した胆汁酸による代謝調節2013
- Author(s)
  渡辺光博
- Journal Title
  
  アンチ・エイジング医学
  
  Volume: ９ Pages: 562-571
- NAID
  40019788812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] 【TGR5】 TGR5/M-Bar/GPBAR/GPR131を介した胆汁酸の新しい機能2013
- Author(s)
  渡辺光博
- Journal Title
  
  たんじゅうさん
  
  Volume: １２ Pages: 16-17
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Cysteine Sulfinic Acid Decarboxylase Regulation: A Role for FXR and SHP in Murine Hepatic Taurine Metabolism2013
- Author(s)
  Kerr TA, Matsumoto Y, Matsumoto H, Xie Y, Hirschberger LL, Stipanuk MH, Anakk S, Moore DD, Watanabe M, Kennedy S, Davidson NO.
- Journal Title
  
  Hepatol Res
  
  Volume: Aug 23
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] 健康長寿と食品因子2013
- Author(s)
  渡辺光博
- Journal Title
  
  日本抗加齢医学会総会プログラム・抄録集13回
  
  Volume: 6 Pages: 84-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] 腸管分泌Angiopoietin like 4による新規肥満治療戦略. 肥満研究2013
- Author(s)
  楠本幸恵, 入江潤一郎, 田川裕恒, 伊藤新, 加藤麻里, 小林奈奈, 田中久美子, 森永理恵子, 藤田真隆, 山田悟, 河合俊英, 尾池雄一, 渡辺光博, 伊藤裕
- Journal Title
  
  肥満研究
  
  Volume: 19 Pages: 136-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Bile Acids Increase Levels of microRNAs 221 and 222, Leading to Degradation of CDX2 During Esophageal Carcinogenesis2013
- Author(s)
  J. Matsuzaki, H. Suzuki, H. Tsugawa, M. Watanabe, S. Hossain, T. Akaike, T. Hibi, et. al.
- Journal Title
  
  Gastroenterology
  
  Volume: (In Press) Issue: 6 Pages: 1300-1311
- DOI
  10.1053/j.gastro.2013.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01350, KAKENHI-PROJECT-23220014, KAKENHI-PROJECT-23580139, KAKENHI-PROJECT-23590482, KAKENHI-PROJECT-23680090, KAKENHI-PROJECT-24659103, KAKENHI-PROJECT-25293178, KAKENHI-PROJECT-25460173, KAKENHI-PROJECT-25460487
[Journal Article] Light-dark condition regulates sirtuin mRNA levels in the retina2013
- Author(s)
  Ban N, Ozawa Y, Inaba T, Miyake S, Watanabe M, Shinmura K, Tsubota K.
- Journal Title
  
  Exp Gerontol
  
  Volume: May 3(pii: S0531-5565(13)00108-3)
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Bile acid binding resin improves metabolic control through the induction of energy expenditure2012
- Author(s)
  Watanabe M(Corresponding Author), Morimoto M, Houten S, Kaneko-Iwasaki N, Sugizaki T, Horai Y, Mataki C, Sato H, Murahashi K, Arita E, Schoonjans K, Suzuki T, Itoh H and Auwerx J.
- Journal Title
  
  PLoS ONE
  
  Volume: 7(8)
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Bile acids induce monocyte differentiation toward IL-12 hypo-producing dendritic cells via a TGR5-dependent pathway2012
- Author(s)
  Ichikawa R, Takayama T, Yoneno K, Kamada N, Kitazume MT, Higuchi H, Matsuoka K, Watanabe M, Itoh H, Kanai T, Hisamatsu T, Hibi T.
- Journal Title
  
  Immunology
  
  Volume: 136 Pages: 153-62
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Bile acid binding resin improves metabolic control through the induction of energy expenditure2012
- Author(s)
  Watanabe M(Corresponding Author), Morimoto K, Houten S, Kaneko-Iwasaki N, Sugizaki T, Horai Y, Mataki C, Sato H, Murahashi K, Arita E, Schoonjans K, Suzuki T, Itoh H and Auwerx J.
- Journal Title
  
  PLoS ONE.
  
  Volume: 7(8)
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] 肥満症の病態と治療に関する最近の知見-肥満症医療の新しい地平】胆汁酸とエネルギー代謝調節2012
- Author(s)
  渡辺光博
- Journal Title
  
  カレントテラピー
  
  Volume: 1 Pages: 515-515
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] 創薬と内分泌代謝疾患胆汁酸代謝制御によるメタボリックシンドローム創薬2012
- Author(s)
  渡辺光博
- Journal Title
  
  日本内分泌学会
  
  Volume: 1 Pages: 165-165
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Bile acids induce monocyte differentiation toward IL-12 hypo-producing dendritic cells via a TGR5-dependent pathway2012
- Author(s)
  Ichikawa R, Takayama T, Yoneno K, Kamada N, Kitazume MT, Higuchi H, Matsuoka K, Watanabe M, Itoh H, Kanai T, Hisamatsu T, Hibi T
- Journal Title
  
  Immunology
  
  Volume: 136 Pages: 153-162
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] 栄養素の受容・情報伝達と代謝制御】胆汁酸の受容体と代謝制御2012
- Author(s)
  杉崎太一、渡辺光博
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: VOL.34no4 Pages: 328-337
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] TGR5 potentiates GLP-1 secretion in response to anionic exchange resins2012
- Author(s)
  Harach T, Pols TW, Nomura M, Maida A, Watanabe M, Auwerx J, Schoonjans K.
- Journal Title
  
  Nature. Sci Rep
  
  Volume: 2 Pages: 430-430
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] TGR5 potentiates GLP-1 secretioen in response to anionic exchange resins.2012
- Author(s)
  Harach T, Pols TW, Nomura M, Maida A, Watanabe M,Auwerx J, Schoonjans K.
- Journal Title
  
  Nature. Sci Rep
  
  Volume: 2 Pages: 430-430
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Dietary lactoferrin alleviates age-related lacrimal gland dysfunction in mice2012
- Author(s)
  Kawashima M, Kawakita T, Inaba T, Okada N, Ito M, Shimmura S, Watanabe M, Shinmura K, Tsubota K.
- Journal Title
  
  PLoS ONE
  
  Volume: 7(3)
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor (FXR) Agonist Induces Obesity and Diabetes through Reduced Energy Expenditure2011
- Author(s)
  Watanabe M (Corresponding Author), Horai Y, Houten SM, Morimoto K, Sugizaki T, Arita E, Mataki C, Sato H, Tanigawara Y, Schoonjans K, Itoh H and Auwerx J.
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 26913-26920
- Data Source
  KAKENHI-PROJECT-23580139
[Journal Article] Lowering bile acid pool size with a synthetic farnesoid X receptor agonist induces obesity and diabetes through reduced energy expenditure2011
- Author(s)
  Watanabe M, et al
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 30 Pages: 26913-26920
- DOI
  10.1074/jbc.m111.248203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390286
[Journal Article] Loss of claudin-15, but not claudin-2, causes Na+ deficiency and glucose malabsorption in mouse small intestine.2011
- Author(s)
  Atsushi Tamura, Hisayoshi Hayashi, Mitsunobu Imasato, Yuji Yamazaki, Asuka Hagiwara, Masami Wada, Tetsuo Noda, Mitsuhiro Watanabe, Yuichi Suzuki, Sachiko Tsukita
- Journal Title
  
  Gastroenterology. 140
  
  Pages: 913-923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580103
[Journal Article] Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor(FXR) Agonist Induces Obesity and Diabetes through Reduced Energy Expenditure2011
- Author(s)
  Watanabe M, Horai Y, Houten SM, Morimoto K, Sugizaki T, Arita E, Mataki C, Sato H, Tanigawara Y, Schoonjans K, H Itoh
- Journal Title
  
  J Bio Chem
  
  Volume: 286(30) Pages: 26913-26920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390286
[Journal Article]2010
- Author(s)
  渡辺光博
- Journal Title
  
  胆汁酸による糖・エネルギー代謝調節(中外医薬社)
  
  Pages: 126-132
- Data Source
  KAKENHI-PROJECT-20580103
[Journal Article] Combined deletion of FXR and SHP results in juvenile onset cholestasis and de novo induction of Cyp17A1.2010
- Author(s)
  Sayeepriyadarshini Anakk, Mitsuhiro Watanabe, Scott A Ochsner, Neil J McKenna, Milton J Finegold, David D Moore.
- Journal Title
  
  J Clin Invest.
  
  Volume: 121 Pages: 86-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580103
[Journal Article] Combined deletion of FXR and SHP results in juvenile onset cholestasis and de novo induction of Cyp17A1.2010
- Author(s)
  Sayeepriyadarshini Anakk, Mitsuhiro Watanabe, Scott A Ochsner, Neil J McKenna, Milton J Finegold, David D Moore
- Journal Title
  
  J Clin Invest. 121
  
  Pages: 86-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580103
[Journal Article] Serum bile acid along with plasma incretins and serum high-mole cular weight adiponectin levels are increased after bariatric surgery2009
- Author(s)
  Nakatani H, Kasama K, Oshiro T, Watanabe M, Hirose H, Itoh H.
- Journal Title
  
  Metabolism 58
  
  Pages: 1400-1407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580103
[Journal Article] Serum bile acid along with plasma incretins and serum high-molecular weight adiponectin levels are increased after bariatric surgery.2009
- Author(s)
  Nakatani H, Kasama K, Oshiro T, Watanabe M, Hirose H, Itoh H
- Journal Title
  
  Metabolism. 58
  
  Pages: 1400-1407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580103
[Journal Article] Loss of Orphan Receptore Small Heterodimer Partner Sensitizes Mice to liver injury from obstructive cholestasis.2008
- Author(s)
  Park YJ, Qatanani M, Chua SS, LaRey JL, Johnson SA, Watanabe M, Moore DD, Lee YK
- Journal Title
  
  Hepatology. 47
  
  Pages: 1578-1586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580103
[Patent] 抗がん剤感受性判定マーカー2009
- Inventor(s)
  谷川原祐介, 渡辺光博, 有田恵理, 西牟田章戸, 山吉康子, 松崎健, 杉本伸二
- Industrial Property Rights Holder
  学校法人慶應義塾株式会社ヤクルト本社
- Filing Date
  2009-01-30
- Data Source
  KAKENHI-PROJECT-20014025
[Presentation] 褐色/ベージュ脂肪細胞と肥満　胆汁酸代謝制御による肥満合併症の予防・治療に関する可能性2023
- Author(s)
  渡辺光博、横山葉子
- Organizer
  肥満学会
- Data Source
  KAKENHI-PROJECT-22K11709
[Presentation] Dietary Protein Quantity Alter Energy Metabolism via Liver-gut interaction signals.2022
- Author(s)
  Yokoyama Y, Tanaka K, Kitamura N, Taworntawat T, Onoue A, Kashikura K, Fukuda S, Honda A, Tsubota K, Watanabe M
- Organizer
  XXVI International Bile Acid Meeting: Bile Acids in Health and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11709
[Presentation] Porphyran, a functional ingredient of traditional Japanese Nori protects against metabolic disease through an intestinal mechanism.2022
- Author(s)
  Watanabe M, Yokoyama Y, Morel JD, Takashina Y, Fukuda S, Kitamura N, Honda A, Arita M, Auwerx J, Tsubota K
- Organizer
  XXVI International Bile Acid Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11751
[Presentation] Dietary Protein Quantity Alter Energy Metabolism via Liver-gut interaction signals.2022
- Author(s)
  Yokoyama Y, Tanaka K, Kitamura N, Taworntawat T, Onoue A, Kashikura K, Fukuda S, Honda A, Tsubota K, Watanabe M
- Organizer
  XXVI International Bile Acid Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11751
[Presentation] 天然物由来機能性物質による肥満関連肝細胞がん発生抑制の検討2022
- Author(s)
  永野詩奈, 北村奈穂, 中村杏菜, 朱き, 北川雛菜, 宮崎照雄, 本多彰, 坪田一男, 横山葉子, 渡辺光博
- Organizer
  肥満学会
- Data Source
  KAKENHI-PROJECT-19K11751
[Presentation] 天然物由来機能性物質の胆汁酸シグナルを介した抗メタボリックシンドローム作用の解析2022
- Author(s)
  細田翔太郎, 平木稜太, 内田瀬奈, 横山葉子, 渡辺光博
- Organizer
  肥満学会
- Data Source
  KAKENHI-PROJECT-19K11751
[Presentation] Porphyran, a functional ingredient of traditional Japanese Nori protects against metabolic disease through an intestinal mechanism2022
- Author(s)
  Watanabe M, Yokoyama Y, Morel JD, Takashina Y, Fukuda S, Kitamura N, Honda A, Arita M, Auwerx J, Tsubota K
- Organizer
  XXVI International Bile Acid Meeting: Bile Acids in Health and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11709
[Presentation] イヌリンおよびセルロースが腸内細菌由来代謝産物を変化させ肥満に及ぼす影響2022
- Author(s)
  渡辺光博, 北川雛菜, 朱き, 中村杏菜, 北村奈穂, 永野詩奈, 宮崎照雄, 本多彰, 横山葉子
- Organizer
  肥満学会
- Data Source
  KAKENHI-PROJECT-19K11751
[Presentation] Bile Acid Signaling is Influenced by Host-Genetic background Altering Gut Microbiota Composition2022
- Author(s)
  Taworntawat Tanon, 川島えり, 星榛香, 西坂観月, 田岡広樹, 本多彰, 宮崎照雄, 福田真嗣, 滝川一, 横山葉子, 松崎靖司, 坪田一男, 渡辺光博
- Organizer
  肥満学会
- Data Source
  KAKENHI-PROJECT-19K11751
[Presentation] Dietary Lower Protein Increased Anti-aging Related Metabolite and Improved Glucose and Lipid Metabolism2019
- Author(s)
  1.Yokoyama Y, Tanaka K, Fukuda S, Shinohara K, Yoshimoto K, Nakamura A, Kitamura N, Miyazaki T, Honda A, Tsubota K, Watanabe M
- Organizer
  The 10th APRU Population Aging Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11751
[Presentation] Difference between two mice strains changes their bile acid composition, gut microbiota, and metabolic regulation system2018
- Author(s)
  N.Kitamura, H.Taoka, T.Tanigaki, E.Kawashima, Y.Yokoyama, A.Nakamura, M. Watanabe
- Organizer
  XXV International Bile Acid Meeting: Bile Acids in Health and Disease 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05292
[Presentation] 分子生物学胆汁酸研究の夜明けと今後の行先2017
- Author(s)
  渡辺光博
- Organizer
  第39回胆汁酸研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05292
[Presentation] 健康長寿における食とサーカディアンリズムの関わり2014
- Author(s)
  渡辺光博
- Organizer
  北海道アンチェイジング学会２０１４
- Place of Presentation
  北海道
- Invited
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 機能食材の研究Update2014
- Author(s)
  渡辺光博
- Organizer
  北海道アンチエイジング学会 2014 北海道
- Place of Presentation
  北海道
- Year and Date
  2014-03-08
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 健康長寿と食品因子2013
- Author(s)
  渡辺光博
- Organizer
  日本抗加齢医学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 肝臓の抗加齢を求めてエネルギー代謝の問題点とその解決に向けて胆汁酸による肝脂質代謝とエネルギー代謝調節2013
- Author(s)
  渡辺光博
- Organizer
  日本抗加齢医学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 胆汁酸代謝調節によるメタボリックシンドローム予防2013
- Author(s)
  渡辺光博
- Organizer
  日本消化器学会
- Place of Presentation
  東京
- Year and Date
  2013-12-07
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] Ｂｉｌｅ　ａｃｉｄ　metabolism for the control of metabolic syndrome2013
- Author(s)
  渡辺光博
- Organizer
  COLD SPRING HARBOR ASIA
- Place of Presentation
  Suzhou.china
- Invited
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] Bile acid metabolism for the control of metabolic syndrome2013
- Author(s)
  M. Watanabe
- Organizer
  Cold Spring Harbor Laboratory Meeting-Nucear Receptors & Disease
- Place of Presentation
  中国
- Year and Date
  2013-11-07
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 健康長寿における食とサーカディアンリズムの関わり2013
- Author(s)
  渡辺光博
- Organizer
  北海道アンチエイジング学会 2013 北海道
- Place of Presentation
  北海道
- Year and Date
  2013-03-02
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 胆汁酸代謝調節によるメタボリックシンドロームへのアプローチ2012
- Author(s)
  渡辺光博
- Organizer
  日本農芸化学会(招待講演)
- Place of Presentation
  京都女子大（京都）
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 概日リズムと健康2012
- Author(s)
  渡辺光博
- Organizer
  抗加齢学会教育講演
- Place of Presentation
  東京
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 胆汁酸代謝制御によるメタボリックシンドローム創薬2012
- Author(s)
  渡辺光博
- Organizer
  日本内分泌学会名古屋
- Place of Presentation
  名古屋
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] The NPCL1 inhibitor ezetimibe improves metabolic disease via decreased LXR Activity2012
- Author(s)
  Watanabe, M.
- Organizer
  Falk Symposium186. Mainz/Germany
- Place of Presentation
  Mainz/Germany
- Year and Date
  2012-10-07
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 胆汁酸とメタボエイジング2012
- Author(s)
  渡辺光博
- Organizer
  第5回東京アンチエイジング学会
- Place of Presentation
  東京
- Year and Date
  2012-05-21
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 代謝調節によるアンチエイジングへのアプローチ2012
- Author(s)
  渡辺光博
- Organizer
  Bio Japan 2012 横浜
- Place of Presentation
  横浜
- Year and Date
  2012-10-10
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] Bile acid binding resins affect diverse molecules to improve metabolic syndrome2012
- Author(s)
  Watanabe, M.
- Organizer
  Falk Symposium 184
- Place of Presentation
  Vienna/Austria
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 第34回胆汁酸代謝調節によるメタボリックシンドローム治療展開2012
- Author(s)
  渡辺光博
- Organizer
  胆汁酸研究会
- Place of Presentation
  名古屋
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 脂肪代謝の重要性2012
- Author(s)
  渡辺光博
- Organizer
  北海道アンチエイジング学会(招待講演)
- Place of Presentation
  ニセコ（北海道）
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] Bile acid metabolism for the control of metabolic disease2012
- Author(s)
  Watanabe, M.
- Organizer
  15th International Congress of Endocrinology and 14th European Congress of Endocrinology
- Place of Presentation
  Florence
- Year and Date
  2012-05-06
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 胆汁酸と腸内環境の重要性2012
- Author(s)
  渡辺光博
- Organizer
  慶應義塾生命科学シンポジウム食と医科学、そして健康長寿第4回東京
- Place of Presentation
  東京
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 代謝とアンチエイジング2011
- Author(s)
  渡辺光博
- Organizer
  北海道アンチエイジング
- Place of Presentation
  北海道
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] 代謝とアンチエイジング2011
- Author(s)
  渡辺光博
- Organizer
  北海道アンチエイジング学会
- Place of Presentation
  北海道
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Bile acids signaling pathway for the control of metabolism2011
- Author(s)
  渡辺光博
- Organizer
  シンポジウム「褐色脂肪研究の新展開」(招待講演)
- Place of Presentation
  北海道大学（北海道）
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] エネルギー代謝調節における胆汁酸とメタボルックシンドローム治療への可能性2011
- Author(s)
  渡辺光博
- Organizer
  第1回褐色脂肪シンポジウム
- Place of Presentation
  北海道
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] The reduction of LXR activity by ezetimibe improves the fatty liver and diabetes.2010
- Author(s)
  渡辺光博
- Organizer
  Cold Spring Harbor Laboratory Meeting-Nucear Receptors & Disease.
- Place of Presentation
  ニューヨーク.USA
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Lowering bile acid pool size with an FXR agonist induces obesity and diabetes through the decrease of energy expenditure2010
- Author(s)
  渡辺光博
- Organizer
  2010 Keystone Symposia
- Place of Presentation
  Keystone
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Lowering bile acid pool size with an FXR agonist induces obesity and diabetes through the decrease of energy expenditure.2010
- Author(s)
  渡辺光博
- Organizer
  2010 Keystone Symposia.
- Place of Presentation
  Keystone. USA
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Decreasing bile acid synthesis with an FXR agonist induces obesity and diabetes through the decrease of energy expenditure.2010
- Author(s)
  渡辺光博
- Organizer
  Falk Symposium 175.
- Place of Presentation
  フライブルグ.ドイツ
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Decreasing bile acid synthesis with an FXR agonist induces obesity and diabetes through the decrease of energy expenditure2010
- Author(s)
  渡辺光博
- Organizer
  Falk Symposium 175.
- Place of Presentation
  フライブルグ.ドイツ
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] The reduction of LXR activity by Ezetimibe improves the metabolic diseases.2010
- Author(s)
  渡辺光博
- Organizer
  American Diabetes Association 70th Scientific sessions.
- Place of Presentation
  オーランド.USA
- Year and Date
  2010-06-27
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] メタボエイジング2010
- Author(s)
  渡辺光博
- Organizer
  北海道アンチエイジング
- Place of Presentation
  北海道
- Year and Date
  2010-03-06
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Bile acid binding resins improve obesity and insulin resistance.2009
- Author(s)
  渡辺光博
- Organizer
  2009 Keystone Symposia. Type 2 Diabetes and Insulin Resistance.
- Place of Presentation
  Banff, Canada.
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Influence of FXR activation in the metabolic control2009
- Author(s)
  渡辺光博
- Organizer
  2009 EMBO Meeting
- Place of Presentation
  クロアチア
- Year and Date
  2009-09-27
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] 胆汁酸代謝調節によるメタボリックシンドローム治療への可能性2009
- Author(s)
  渡辺光博
- Organizer
  第45回高血圧関連疾患モデル学会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Bile acids binding resins improve metabolic syndrome.2009
- Author(s)
  渡辺光博
- Organizer
  2009 Keystone Symposia. Type 2 Diabetes and Insulin Resistance.
- Place of Presentation
  Banff. Canada
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Influence of FXR activation in the metabolic control.2009
- Author(s)
  渡辺光博
- Organizer
  2009 EMBO Meeting.
- Place of Presentation
  クロアチア
- Year and Date
  2009-09-27
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] 胆汁酸代謝調節によるメタボルックシンドローム治療への可能性2009
- Author(s)
  渡辺光博
- Organizer
  第45回高血圧関連疾患モデル学会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Bile acid control the metabolic signaling.2008
- Author(s)
  渡辺光博
- Organizer
  Proceeding of the CBI Society Annual Meeting 2008.
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Bile acid binding resins improve obesity and Insulin resistance.2008
- Author(s)
  渡辺光博
- Organizer
  CBI Society Annual Meeting 2008 (International Synposium)
- Place of Presentation
  Tokyo
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Bile signaling pathway for the control the metabolism.2008
- Author(s)
  渡辺光博
- Organizer
  1st International Conference of Health and -Longevity Sciences.
- Place of Presentation
  Shizuoka
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Discovery of blood biomarkers to predict sensitivity to CPT-11 by metabolome analysis2008
- Author(s)
  Mitsuhiro Watanabe
- Organizer
  CBI Society Annual Meeting 2008(International Symposium)
- Place of Presentation
  Tokyo(Japan)
- Year and Date
  2008-10-23
- Data Source
  KAKENHI-PROJECT-20014025
[Presentation] Bile signaling pathway for the control the metabolism.2008
- Author(s)
  渡辺光博
- Organizer
  1st International Conference of Health and Longevity Sciences.
- Place of Presentation
  静岡
- Year and Date
  2008-12-19
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Bile acid control the metabolic signaling.2008
- Author(s)
  渡辺光博
- Organizer
  Proceeding of the CBI Society Annual Meeting 2008.
- Place of Presentation
  東京
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Bile acid binding resins improve metabolic control through the induction of energy expenditure.2008
- Author(s)
  渡辺光博
- Organizer
  XX International Bile Acid Meeting 2008.
- Place of Presentation
  Amsterdam, The Netherlands.
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Discovery of blood biomarkers to predict sensitivity to CPT-11 by metabolome analysis2008
- Author(s)
  Mitsuhiro Watanabe
- Organizer
  CBI Society Annual Meeting 2008(International Symposium)
- Place of Presentation
  Tokyo (Japan)
- Year and Date
  2008-10-23
- Data Source
  KAKENHI-PROJECT-20390049
[Presentation] 胆汁酸代謝調節によるメタボリックシンドローム治療への可能性2008
- Author(s)
  渡辺光博
- Organizer
  第45回高血圧関連疾患モデル学会シンポジウム
- Place of Presentation
  筑波
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] The blood biomarkers to predict sensitivity to CPT-11 by metabolome analysis2008
- Author(s)
  Mitsuhiro Watanabe
- Organizer
  CBI Society Annual Meeting 2008
- Place of Presentation
  Tokyo (Japan)
- Year and Date
  2008-10-22
- Data Source
  KAKENHI-PROJECT-20390049
[Presentation] Metabolic regulation via bile acid2008
- Author(s)
  渡辺光博
- Organizer
  第40回日本動脈硬化学会総会・学術集会シンポジウム
- Place of Presentation
  筑波
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-20580103
[Presentation] Bile acid metabolism for the control of metabolic disease
- Author(s)
  Watanabe, M
- Organizer
  15th International Congress of Endocrinology and 14th European Congress of Endocrinology
- Place of Presentation
  Florence
- Invited
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 胆汁酸代謝制御によるメタボリックシンドローム創薬
- Author(s)
  渡辺光博
- Organizer
  日本内分泌学会
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 胆汁酸代謝調節によるメタボリックシンドローム治療展開
- Author(s)
  渡辺光博
- Organizer
  第34回　胆汁酸研究会
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] Bile acid binding resins affect diverse molecules to improve metabolic syndrome.
- Author(s)
  Watanabe, M
- Organizer
  Falk Symposium 184
- Place of Presentation
  Vienna/Austria
- Invited
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 胆汁酸とエネルギー
- Author(s)
  渡辺光博
- Organizer
  第３５回胆汁酸研究会
- Place of Presentation
  北海道
- Invited
- Data Source
  KAKENHI-PROJECT-23580139
[Presentation] 胆汁酸吸着レジンの抗肥満効果における腸内細菌、腸管環境の意義
- Author(s)
  添田幸恵、入江潤一郎、田川裕恒、伊藤新、加藤麻里、小林奈奈、田中久美子、山田悟、河合俊英、尾池雄一、渡辺光博、伊藤裕
- Organizer
  第５５回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591342
[Presentation] The NPCL1 inhibitor ezetimibe improves metabolic disease via decreased LXR
- Author(s)
  Watanabe, M
- Organizer
  Falk Symposium186
- Place of Presentation
  Mainz/German
- Invited
- Data Source
  KAKENHI-PROJECT-23580139

1. TANIGAWARA Yusuke (30179832)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. YOKOYAMA Yoko (10617244)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
3. MORIMOTO Kokichi (10468506)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. ITOH Hiroshi (40252457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 三上俊夫 (60199966)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 荒川亮介 (40350095)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SUGIZAKI Taichi (00468480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKAE Jun (00344573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SONE Masakatsu (40437207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ICHIHARA Atsuhiro (60203105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SASAMURA Hiroyuki (00235293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHIBATA Hirotaka (20245484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. WAKINO Shu (50265823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MIYASHITA Kazutoshi (50378759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. IRIE JUNICHIRO (70306687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. 西牟田章戸 (00424135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 滝川一 (70197226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 松崎靖司 (50209532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 金芝美 (00868177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 朴ジョンヒョク (80835843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MIZUNO Yosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. MIZUNO Yumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. HOSSAIN M.S.

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. HOSSAIN Md. Shariff

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. HOSSAIN Md.Sharif

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Watanabe Mitsuhiro 渡辺 光博

WATANABE Mitsuhiro 渡辺 光博

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Promotion of personalized medicine for lifestyle-related diseases by revealing bile acids, microbiota and cell signaling interactionPrincipal Investigator

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The expression of beta-oxidation adjustment key factor ACC2 elucidation which aimed at the metabolic syndrome new therapyPrincipal Investigator

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Approach to metabolic syndrome by analysing the energy metabolism homeostasisPrincipal Investigator

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[Book] あなたの健康寿命はもっとのばせる！2017

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[Book] 糖尿病に効く！胆汁酸健康法2014

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[Book] くらしと胆汁酸 胆汁酸と代謝調節. たんじゅうさん(1348-0189) 2013 12 巻2 号2013

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[Book] 「糖尿病に効く!胆汁酸健康法」2013

Author(s)

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Watanabe Mitsuhiro 渡辺光博

WATANABE Mitsuhiro 渡辺光博

[Book] くらしと胆汁酸胆汁酸と代謝調節. たんじゅうさん(1348-0189) 2013 12 巻2 号2013

[Book] 【肥満症の病態と治療に関する最近の知見-肥満症医療の新しい地平】胆汁酸とエネルギー代謝調節. カレントテラピー 30 巻 6 号2012

[Book] 【消化管とエネルギー代謝】胆汁酸による代謝調節. Medical Science Digest 2011 : 37 巻2011

[Book] 【腎における内分泌関連トピックス】胆汁酸のホルモン様作用メタボリックシンドロームへの関与. 腎と透析 2011 : 71 巻2011

[Book] 【核内受容体とアディポサイエンス】LXR、FXR、PXR、TR とアディポサイエンスコレステロール関連化合物がつなぐ核内受容体群. Adiposcience 2011 : 7 巻2011

[Book] 【メタボリックシンドロームと臓器連関】胆汁酸による代謝臓器間連関. Medical Science Digest 2011 : 37 巻2011