Kuba Keiji 久場敬司

… Alternative Names

Keiji Kuba 久場敬司

KUBA Keiji 久場敬司

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Researcher Number	10451915
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 九州大学, 医学研究院, 教授 2022 – 2023: 秋田大学, 医学系研究科, 非常勤講師 2021 – 2022: 九州大学, 大学院医学研究院, 教授 2017 – 2021: 秋田大学, 医学系研究科, 教授 2017: 秋田大学, 大学院医学系研究科分子機能学・代謝機能学講座, 教授 … More 2014 – 2017: 秋田大学, 医学(系)研究科(研究院), 教授 2011: Akita University, 医学(系)研究科(研究院), 准教授 2009 – 2010: Akita University, 大学院・医学系研究科, 准教授 2008: Akita University, 医学部, 准教授 2007: Tokyo Medical and Dental University, 難治疾患研究所, 特任講師 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Basic Section 48030:Pharmacology-related / General pharmacology / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Medium-sized Section 52:General internal medicine and related fields / Cardiovascular medicine / Pathological medical chemistry Except Principal Investigator Basic Section 49030:Experimental pathology-related / Basic Section 49010:Pathological biochemistry-related / Basic Section 55020:Digestive surgery-related / Basic Section 54010:Hematology and medical oncology-related / Emergency medicine / General pharmacology
Keywords	Principal Investigator 心不全 / CCR4-NOT / RNA / CNOT3 / heart failure / ACE2 / 転写 / エピジェネティクス / 急性肺傷害 / ARDS … More / Apelin / アンジオテンシン / CNOT10 / 蛋白間相互作用 / 空間的トランスクリプトーム解析 / 好中球 / G-CSF / がん微小環境 / Galectin-7 / T細胞 / 空間的トランスクリプトーム / 転移 / 腫瘍免疫 / 扁平上皮癌 / ユビキチン化 / エピトランスクリプトーム / 脂肪細胞 / 肥満 / CCR-NOT / ユビキチン修飾 / 翻訳 / RNA分解 / 進化 / 血管透過性 / 急性呼吸窮迫症候群 / 敗血症 / COVID-19 / SARS-CoV-2 / B38-CAP / cell death / cardiomyocyte / Atg7 / nucleotide / transcription / fibroblasts / ATP / translation / ace2 / ubiquitination / deadenylation / CRISPR / Elabela / ゲノム編集 / FoxM1 / CRISPR/Cas9 / ELABELA / 心臓 / poly(A) / ＣＣＲ４－ＮＯＴ / 遺伝子改変マウス / RNA創薬 / 循環器 / 脱アデニル化 / RNA代謝 / ネクローシス / オートファジー / デアデニレース / deadenylase / QT時間 / ショウジョウバエ / H5N1 / 高病原性インフルエンザ / 酸化リン脂質 / 自然免疫 / Toll-like receptor 4 / 酸化ストレス / SARS … More Except Principal Investigator mRNA代謝 / 自然リンパ球 / 空間的トランスクリプトーム解析 / ３型免疫 / ２型免疫 / １型免疫 / Galectin-7 / 免疫抑制 / がん微小環境 / 転移 / MDSCs / G-CSF / 扁平上皮癌 / 転写後調節 / ILC3 / ILC2 / ILC1 / NK細胞 / 転写後制御 / エピトランスクリプトーム / 固形癌 / 炎症 / ｍRNA / microRNA / RNA-seq解析 / 腫瘍免疫 / Galectin / リンパ節転移 / 標的治療 / ゲノム編集 / 機能解析 / 遺伝子変異 / 免疫抑制療法 / 体細胞変異 / 骨髄系腫瘍関連遺伝子 / 再発・難治性 / 後天性赤芽球癆 / ウイルス感染 / 重症感染症 / クロマチン / ウイルス / 心肥大 / レニンアンジオテンシン系 / 心保護効果 / 心腎連関 / 心不全 / APJ / ELABELA Less

Elucidation of RNA-guided molecular networks in response to heart failure stressPrincipal Investigator
- Principal Investigator
  
  久場敬司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kyushu University
免疫体質を規定するRNA代謝ネットワークの解析
- Principal Investigator
  
  海老原敬
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Akita University
癌の転移・再発における細胞外Galectin-Xを介した免疫抑制機構の解明
- Principal Investigator
  
  安健博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Akita University
Spatial transcriptome analysis of highly metastatic tumours to develop new methods for the prediction and treatment of cancer metastasisPrincipal Investigator
- Principal Investigator
  
  Kuba Keiji
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyushu University
  Akita University
mRNA metabolism specific to ILC subsets
- Principal Investigator
  
  Ebihara Takashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Akita University
RNA modification affecting lymph node metastasis in esophageal cancer
- Principal Investigator
  
  Motoyama Satoru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Akita University
Development of a bacteria-derived ACE2-like enzyme as a therapeutics for treating cardiovascular diseasesPrincipal Investigator
- Principal Investigator
  
  Kuba Keiji
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Akita University
Mechanistic insights into spatio-temporal regulation of RNA in cardio-metabolic diseasePrincipal Investigator
- Principal Investigator
  
  Kuba Keiji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Akita University
後天性赤芽球癆における体細胞遺伝子変異の機能解明と新規治療基盤の開発
- Principal Investigator
  
  廣川誠
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Akita University
RNA metabolism-based regulation of heart function and its application for treatment of heart failurePrincipal Investigator
- Principal Investigator
  
  Kuba Keiji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Akita University
Identification of higher-order-epigenetic modification machineries and development of potential novel therapeutics in severe virus infection
- Principal Investigator
  
  Imai Yumiko
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Emergency medicine
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
Dissecting the functional role of a novel ligand for APJ, ELABELA, in cardio-renal connection
- Principal Investigator
  
  SATO Teruki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Akita University
Application of genome editing and development-associated APJ ligand for exploring novel therapeutic candidates for heart failurePrincipal Investigator
- Principal Investigator
  
  Keiji Kuba
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Akita University
Mechanistic insight into CCR4-NOT deadenylase-mediated heart function control and its potential application for therapeuticsPrincipal Investigator
- Principal Investigator
  
  Kuba Keiji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Akita University
ヒト心疾患感受性遺伝子群の迅速な生体内機能解析法の開発Principal Investigator
- Principal Investigator
  
  久場敬司
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Akita University
CCR4-NOT複合体による心機能制御の分子機構の解明研究Principal Investigator
- Principal Investigator
  
  久場敬司
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Akita University
ショウジョウバエ、マウス、ヒト間で保存された疾患発症シグナルの解析研究Principal Investigator
- Principal Investigator
  
  久場敬司
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Akita University
Dissecting the molecular mechanisms for SARS receptor ACE2-mediatedlung protection in ARDS/acute lung injuryPrincipal Investigator
- Principal Investigator
  
  KUBA Keiji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Akita University
  Tokyo Medical and Dental University

[Book] Encyclopedia ofMolecular Mechanisms of Disease edited byFlorian Lang, Tubingen
- Author(s)
  Kuba K, Imai Y, Penninger JM
- Publisher
  Severe acuterespiratory distress syndrome(in press)
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy2023
- Author(s)
  Yamada T, Tatematsu M, Takasuga S, Fuchimukai A, Yamagata K, Seki S, Kuba K, Yoshida H, Taniuchi I, Bernhardt G, Shibuya K, Shibuya A, Yamada T, Ebihara T.
- Journal Title
  
  J Exp Med
  
  Volume: 220 Issue: 7 Pages: 20222005-20222005
- DOI
  10.1084/jem.20222005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06542, KAKENHI-PROJECT-20H03832, KAKENHI-PROJECT-23K08954, KAKENHI-PROJECT-21K19368, KAKENHI-PROJECT-22K19551, KAKENHI-PLANNED-19H05747
[Journal Article] Squamous cell carcinoma‐derived <scp>G‐CSF</scp> promotes tumor growth and metastasis in mice through neutrophil recruitment and tumor cell proliferation, associated with poor prognosis of the patients2023
- Author(s)
  Kemuriyama Kohei、An Jianbo、Motoyama Satoru、Nagaki Yushi、Yamaguchi Tomokazu、Sato Yusuke、Wakita Akiyuki、Minamiya Yoshihiro、Kuba Keiji
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 8 Pages: 573-584
- DOI
  10.1111/gtc.13051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06907, KAKENHI-PROJECT-23K06146, KAKENHI-PROJECT-22K19551
[Journal Article] Apelin expression is downregulated in T cells in a murine model of chronic colitis2023
- Author(s)
  Yamada D、Kojima Yi、Hosoya A、Suzuki、Watabe T、Inoue T、Tsugawa N、Asakawa T、Yonemoto Y、Onizawa M、Nemoto Y、Oshima S、Shimonaka M、Kuba Ki、Ishida J、Fukamizu A、Penninger JM、Watanabe M、Okamoto R、Nagaishi T
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 647 Pages: 72-79
- DOI
  10.1016/j.bbrc.2023.01.068
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05986, KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-22K19551, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-21H02897, KAKENHI-PROJECT-20K08304
[Journal Article] Peritumoral CD16b positive-neutrophil accumulation strongly correlates with regional lymph node metastasis in thoracic esophageal squamous cell cancer.2022
- Author(s)
  Fujita H, Motoyama S,　An　J, Nagakai　Y, Yamaguchi T, Koyota S, Sato　Y, Wakita A, Imai K. Kuba K, Minamiya Y.
- Journal Title
  
  Surgery
  
  Volume: Online ahead of print
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09048
[Journal Article] ACE2の循環器疾患および感染症における意義2022
- Author(s)
  久場敬司
- Journal Title
  
  CARDIAC PRACTICE
  
  Volume: 2 Pages: 36-41
- Data Source
  KAKENHI-PROJECT-20H03426
[Journal Article] Identification of Galectin-7 as a crucial metastatic enhancer of squamous cell carcinoma associated with immunosuppression2022
- Author(s)
  An Jianbo、Nagaki Yushi、Motoyama Satoru、Kuze Yuta、Hoshizaki Midori、Kemuriyama Kohei、Yamaguchi Tomokazu、Ebihara Takashi、Minamiya Yoshihiro、Suzuki Yutaka、Imai Yumiko、Kuba Keiji
- Journal Title
  
  Oncogene
  
  Volume: 41 Issue: 50 Pages: 5319-5330
- DOI
  10.1038/s41388-022-02525-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06907, KAKENHI-PROJECT-21K19368, KAKENHI-PROJECT-22K19551, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-20K09048, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-21H02707
[Journal Article] ACE2の循環器疾患および感染症における意義2022
- Author(s)
  久場敬司
- Journal Title
  
  CARDIAC PRACTICE
  
  Volume: 2 Pages: 36-41
- Data Source
  KAKENHI-PROJECT-20K21566
[Journal Article] Peritumoral CD16b positive-neutrophil accumulation strongly correlates with regional lymph node metastasis in thoracic esophageal squamous cell cancer2022
- Author(s)
  Fujita Hiromu、Motoyama Satoru、An Jianbo、Nagakai Yushi、Yamaguchi Tomokazu、Koyota Souichi、Sato Yusuke、Wakita Akiyuki、Imai Kazuhiro、Kuba Keiji、Minamiya Yoshihiro
- Journal Title
  
  Surgery
  
  Volume: S0039-6060 Issue: 6 Pages: 1170-1170
- DOI
  10.1016/j.surg.2021.11.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-22K06907, KAKENHI-PROJECT-20K07285
[Journal Article] ACE2-like enzyme B38-CAP suppresses abdominal sepsis and severe acute lung injury2022
- Author(s)
  Minato Takafumi、Yamaguchi Tomokazu、Hoshizaki Midori、Nirasawa Satoru、An Jianbo、Takahashi Saori、Penninger Josef M.、Imai Yumiko、Kuba Keiji
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 7 Pages: 0270920-0270920
- DOI
  10.1371/journal.pone.0270920
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19551, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-17H06179
[Journal Article] Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation2021
- Author(s)
  Shiimori Masami、Ichida Yu、Nukiwa Ryota、Sakuma Toshie、Abe Haruka、Kajitani Rei、Fujino Yuji、Kikuchi Akira、Kawamura Takeshi、Kodama Tatsuhiko、Toyooka Shinichi、Shirahige Katsuhiko、Schotta Gunnar、Kuba Keiji、Itoh Takehiko、Imai Yumiko
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 6 Pages: 102660-102660
- DOI
  10.1016/j.isci.2021.102660
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-21H04797
[Journal Article] Angiotensin-Converting Enzyme 2 (ACE2) in the Pathogenesis of ARDS in COVID-192021
- Author(s)
  Kuba Keiji、Yamaguchi Tomokazu、Penninger Josef M.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 732690-732690
- DOI
  10.3389/fimmu.2021.732690
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20K07285
[Journal Article] Highly susceptible SARS-CoV-2 model in CAG promoter?driven hACE2-transgenic mice2021
- Author(s)
  Asaka Masamitsu N.、Utsumi Daichi、Kamada Haruhiko、Nagata Satoshi、Nakachi Yutaka、Yamaguchi Tomokazu、Kawaoka Yoshihiro、Kuba Keiji、Yasutomi Yasuhiro
- Journal Title
  
  JCI Insight
  
  Volume: 6 Issue: 19 Pages: 1-2
- DOI
  10.1172/jci.insight.152529
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-21K19395, KAKENHI-PROJECT-21K16333
[Journal Article] COVID-19の発症機序2021
- Author(s)
  久場敬司
- Journal Title
  
  月刊心臓
  
  Volume: 53 Pages: 1-1
- Data Source
  KAKENHI-PROJECT-20H03426
[Journal Article] COVID-19の発症機序2021
- Author(s)
  久場敬司
- Journal Title
  
  月刊心臓
  
  Volume: 53 Pages: 1-1
- Data Source
  KAKENHI-PROJECT-20K21566
[Journal Article] 種を超えて保存されたACE2様酵素B38-CAPの循環器疾患への治療応用2021
- Author(s)
  久場敬司
- Journal Title
  
  BIO Clinica
  
  Volume: 36 Pages: 228-230
- Data Source
  KAKENHI-PROJECT-20H03426
[Journal Article] Suv4-20h2 protects from influenza virus infection through suppression of chromatin loop formation2021
- Author(s)
  Shiimori M, Ichida Y, Nukiwa R, Kajitani R, Fujino Y, Kikuchi A, Kawamura T, Kodama T, Toyooka S, Shirahige K, Schotta G, Kuba K, Itoh T, and Imai Y
- Journal Title
  
  iScience
  
  Volume: in　press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06179
[Journal Article] Clonal hematopoiesis in adult pure red cell aplasia2021
- Author(s)
  Fujishima N、Kohmaru J、Koyota S、Kuba K、Saga T、Omokawa A、Moritoki Y、Ueki S、Ishida F、Nakao S、Matsuda A、Ohta A、Tohyama K、Yamasaki H、Usuki K、Nakashima Y、Sato S、Miyazaki Y、Nannya Y、Ogawa S、Sawada K、Mitani K、Hirokawa M
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 2253-2253
- DOI
  10.1038/s41598-021-81890-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08709, KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-19K08822
[Journal Article] Incomplete antiviral treatment may induce longer durations of viral shedding during SARS-CoV-2 infection2021
- Author(s)
  Kim Kwang Su、Iwanami Shoya、Oda Takafumi、Fujita Yasuhisa、Kuba Keiji、Miyazaki Taiga、Ejima Keisuke、Iwami Shingo
- Journal Title
  
  Life Science Alliance
  
  Volume: 4 Issue: 10 Pages: e202101049-e202101049
- DOI
  10.26508/lsa.202101049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20H03426, KAKENHI-PUBLICLY-20H05042
[Journal Article] 種を超えて保存されたACE2様酵素B38-CAPの循環器疾患への治療応用2021
- Author(s)
  久場敬司
- Journal Title
  
  BIO Clinica
  
  Volume: 36 Pages: 228-230
- Data Source
  KAKENHI-PROJECT-20K21566
[Journal Article] ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury2021
- Author(s)
  Yamaguchi T, Hoshizaki M, Minato T, Nirasawa S, Asaka MN, Niiyama M, Imai M, Uda A, Chan JF, Takahashi S, An J, Saku A, Nukiwa R, Utsumi D, Kiso M, Yasuhara A, Poon VK, Chan CC, Fujino Y, Motoyama S, Nagata S, Penninger JM, Kamada H, Yuen KY, Kamitani W, Maeda K, Kawaoka Y, Yasutomi Y, Imai Y, Kuba Keiji
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 6791-6791
- DOI
  10.1038/s41467-021-27097-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20K16153, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-21K19395, KAKENHI-PROJECT-17H06179
[Journal Article] SARS-CoV-2とRAS/ACE22021
- Author(s)
  久場敬司
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 11 Pages: 32-36
- Data Source
  KAKENHI-PROJECT-20H03426
[Journal Article] SARS-CoV-2とRAS/ACE22021
- Author(s)
  久場敬司
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 11
- Data Source
  KAKENHI-PROJECT-20K21566
[Journal Article] 微生物由来の新規ACE2様酵素による循環器疾患症状の改善2020
- Author(s)
  久場敬司，韮澤悟
- Journal Title
  
  BIOSCIENCE & INDUSTRY
  
  Volume: 78 Pages: 512-513
- Data Source
  KAKENHI-PROJECT-20H03426
[Journal Article] 新規微生物由来酵素B38-CAPはACE2活性により高血圧と心不全を改善する2020
- Author(s)
  湊隆文，久場敬司
- Journal Title
  
  実験医学
  
  Volume: 38 Pages: 2371-2374
- Data Source
  KAKENHI-PROJECT-20H03426
[Journal Article] m6A demethylase ALKBH5 promotes proliferation of esophageal squamous cell carcinoma associated with poor prognosis2020
- Author(s)
  Nagaki Yushi、Motoyama Satoru、Yamaguchi Tomokazu、Hoshizaki Midori、Sato Yusuke、Sato Teruki、Koizumi Yukio、Wakita Akiyuki、Kawakita Yuta、Imai Kazuhiro、Nanjo Hiroshi、Watanabe Hiroyuki、Imai Yumiko、Minamiya Yoshihiro、Kuba Keiji
- Journal Title
  
  Genes to Cells
  
  Volume: 25 Issue: 8 Pages: 547-561
- DOI
  10.1111/gtc.12792
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-20K09048, KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-16H06279
[Journal Article] B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction2020
- Author(s)
  Minato T, Nirasawa S, Sato T, Yamaguchi T, Hoshizaki M, Inagaki T, Nakahara K, Yoshihashi T, Ozawa R, Yokota S, Natsui M, Koyota S, Yoshiya T, Yoshizawa-Kumagaye K, Motoyama S, Gotoh T, Nakaoka Y, Penninger JM, Watanabe H, Imai Y, Takahashi S, Kuba K
- Journal Title
  
  Nature Communications
  
  Volume: 11(1) Issue: 1 Pages: 1058-1058
- DOI
  10.1038/s41467-020-14867-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-18K15038, KAKENHI-PROJECT-18K15879, KAKENHI-PROJECT-19K08483
[Journal Article] 微生物由来の新規ACE2様酵素による循環器疾患症状の改善2020
- Author(s)
  久場敬司，韮澤悟
- Journal Title
  
  BIOSCIENCE & INDUSTRY
  
  Volume: 78 Pages: 512-513
- Data Source
  KAKENHI-PROJECT-20K21566
[Journal Article] Virus database annotations assist in tracing information on patients infected with emerging pathogens2020
- Author(s)
  Akiko Nakashima, Mitsue Takeya, Keiji Kuba, Makoto Takano, Noriyuki Nakashima
- Journal Title
  
  Informatics in Medicine Unlocked
  
  Volume: 100442 Pages: 100442-100442
- DOI
  10.1016/j.imu.2020.100442
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08553, KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20K16125, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-18K15018
[Journal Article] 新規微生物由来酵素B38-CAPはACE2活性により高血圧と心不全を改善する2020
- Author(s)
  湊隆文，久場敬司
- Journal Title
  
  実験医学
  
  Volume: 38 Pages: 2371-2374
- Data Source
  KAKENHI-PROJECT-20K21566
[Journal Article] ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury2020
- Author(s)
  Minato T, Hoshizaki M, Yamaguchi T, Nirasawa S, Asaka MN, Kamada H, Yuen KM, Kawaoka Y, Yasutomi Y, Imai Y, Kuba K, et al.
- Journal Title
  
  researchsquare.com/article/rs-124634/v1
  
  Volume: -
- DOI
  10.21203/rs.3.rs-124634/v1
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20H03426
[Journal Article] Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability2020
- Author(s)
  Mostafa Dina、Takahashi Akinori、Yanagiya Akiko、Yamaguchi Tomokazu、Abe Takaya、Kureha Taku、Kuba Keiji、Kanegae Yumi、Furuta Yasuhide、Yamamoto Tadashi、Suzuki Toru
- Journal Title
  
  RNA Biology
  
  Volume: 17 Issue: 3 Pages: 403-416
- DOI
  10.1080/15476286.2019.1709747
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06975, KAKENHI-PROJECT-18K07079, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-18K15038, KAKENHI-PROJECT-20K08195
[Journal Article] Eosinophils promote corneal wound healing via the 12/15‐lipoxygenase pathway2020
- Author(s)
  Ogawa Mamoru、Ishihara Tomoaki、Isobe Yosuke、Kato Taiga、Kuba Keiji、Imai Yumiko、Uchino Yuichi、Tsubota Kazuo、Arita Makoto
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 9 Pages: 12492-12501
- DOI
  10.1096/fj.202000483r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20H00495
[Journal Article] The CCR4-NOT complex maintains liver homeostasis through mRNA deadenylation2020
- Author(s)
  Takahashi Akinori、Suzuki Toru、Soeda Shou、Takaoka Shohei、Kobori Shungo、Yamaguchi Tomokazu、Mohamed Haytham Mohamed Aly、Yanagiya Akiko、Abe Takaya、Shigeta Mayo、Furuta Yasuhide、Kuba Keiji、Yamamoto Tadashi
- Journal Title
  
  Life Science Alliance
  
  Volume: 3 Issue: 5 Pages: 1-19
- DOI
  10.26508/lsa.201900494
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06975, KAKENHI-PROJECT-18K07079, KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20H03426
[Journal Article] Genome‐Scale CRISPR/Cas9 Screening Reveals Squalene Epoxidase as a Susceptibility Factor for Cytotoxicity of Malformin A12019
- Author(s)
  Koizumi Yukio、Fukushima Jun、Kobayashi Yayoi、Kadowaki Ayumi、Natsui Miyuki、Yamaguchi Tomokazu、Imai Yumiko、Sugiyama Toshihiro、Kuba Keiji
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Issue: 12 Pages: 1-7
- DOI
  10.1002/cbic.201800769
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15038, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-17K19693, KAKENHI-PLANNED-15H05978
[Journal Article] The functional role of endogenous APJ agonists; Apelin and Elabela/Toddler in cardiovascular diseases2019
- Author(s)
  Sato Teruki、Kuba Keiji
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 153 Issue: 4 Pages: 172-178
- DOI
  10.1254/fpj.153.172
- NAID
  130007630616
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15879, KAKENHI-PROJECT-17H04028
[Journal Article] Apelin inhibition prevents resistance and metastasis associated with anti‐angiogenic therapy2019
- Author(s)
  Uribesalgo I, Hoffmann D, Zhang Y, Kavirayani A, Lazovic J, Berta J, Novatchkova M, Pai TP, Wimmer RA, Laszlo V, Schramek D, Karim R, Tortola L, Deswal S, Haas L, Zuber J, Szucs M, Kuba K, Dome B, Cao Y, Haubner B, Penninger JM
- Journal Title
  
  EMBO Molecular Medicine
  
  Volume: 11 Issue: 8
- DOI
  10.15252/emmm.201809266
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04028
[Journal Article] The CCR4-NOT deadenylase complex maintains adipocyte identity2019
- Author(s)
  Takahashi A., Takaoka S., Kobori S., Yamaguchi T., Ferwati S., Kuba K., Yamamoto T., and Suzuki T.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 20 Issue: 21 Pages: 5274-5274
- DOI
  10.3390/ijms20215274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07079, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-18K15038
[Journal Article] Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling2019
- Author(s)
  Sato Teruki、Kadowaki Ayumi、Suzuki Takashi、Ito Hiroshi、Watanabe Hiroyuki、Imai Yumiko、Kuba Keiji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 2 Pages: 239-239
- DOI
  10.3390/ijms20020239
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15879, KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-16K09415, KAKENHI-PROJECT-17K19693
[Journal Article] Apelin and Elabela/Toddler; double ligands for APJ/Apelin receptor in heart development, physiology, and pathology.2018
- Author(s)
  Kuba K, Sato T, Imai Y, Yamaguchi T
- Journal Title
  
  Peptides.
  
  Volume: in press Pages: 62-70
- DOI
  10.1016/j.peptides.2018.04.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19013, KAKENHI-PROJECT-18K15038, KAKENHI-PROJECT-18K15879, KAKENHI-PROJECT-17H04028
[Journal Article] Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection.2018
- Author(s)
  Fujiwara S., Hoshizaki M., Ichida Y., Lex D., Kuroda E., Ishii KJ., Magi S., Okada M., Takao H., Gando M., Imai H., Hara R., Herzog H., Yoshimura A., Okamura H., Penninger JM., Slutsky AS., Uhlig S., Kuba K., and Imai Y.
- Journal Title
  
  Nature Microbiology
  
  Volume: 4(2) Issue: 2 Pages: 258-268
- DOI
  10.1038/s41564-018-0289-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05970, KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-16H05256, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-17K19693, KAKENHI-PROJECT-17H06175
[Journal Article] The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function2018
- Author(s)
  Yamaguchi Tomokazu et al
- Journal Title
  
  Science Signaling
  
  Volume: 11 Issue: 516 Pages: 3638-3638
- DOI
  10.1126/scisignal.aan3638
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05265, KAKENHI-PROJECT-17K07292, KAKENHI-PROJECT-17K19693, KAKENHI-PLANNED-15H05978, KAKENHI-PUBLICLY-17H05610, KAKENHI-PUBLICLY-17H06018, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-16H05296, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-15KT0147, KAKENHI-PROJECT-15K18480, KAKENHI-PROJECT-16K19013, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18K15879, KAKENHI-PUBLICLY-17H05607, KAKENHI-PROJECT-16H04745, KAKENHI-PROJECT-16K09415, KAKENHI-PROJECT-16K14652, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-17H01533
[Journal Article] Involvement of RSK1 activation in malformin-enhanced cellular fibrinolytic activity2018
- Author(s)
  Koizumi Y, Nagai K, Gao L, Koyota S, Yamaguchi T, Natsui M, Imai Y, Hasumi K, Sugiyama T, Kuba K
- Journal Title
  
  Sci Rep
  
  Volume: 8(1) Issue: 1 Pages: 5472-5472
- DOI
  10.1038/s41598-018-23745-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-17K19693
[Journal Article] New aspects of poly(A) tail shortening of mRNA in controlling heart functions2018
- Author(s)
  Kuba K.
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 151 Issue: 3 Pages: 94-99
- DOI
  10.1254/fpj.151.94
- NAID
  130006470906
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-17H04028
[Journal Article] ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage2017
- Author(s)
  Sato T, Sato C, Kadowaki A, Watanabe H, Ho L, Ishida J, Yamaguchi T, Kimura A, Fukamizu A, Penninger JM, Reversade B, Ito H, Imai Y, Kuba K
- Journal Title
  
  Cardiovasc Res
  
  Volume: 113(7) Issue: 7 Pages: 760-769
- DOI
  10.1093/cvr/cvx061
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253083, KAKENHI-PROJECT-26293050, KAKENHI-PROJECT-15K15304, KAKENHI-PROJECT-15K18965, KAKENHI-PROJECT-16K19013, KAKENHI-PROJECT-17K07131, KAKENHI-PROJECT-17K19693, KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H01519, KAKENHI-PROJECT-16H05296, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-17H06179
[Journal Article] Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives2017
- Author(s)
  Freyer Laina、Hsu Chih-Wei、Nowotschin Sonja、Pauli Andrea、Ishida Junji、Kuba Keiji、Fukamizu Akiyoshi、Schier Alexander F.、Hoodless Pamela A.、Dickinson Mary E.、Hadjantonakis Anna-Katerina
- Journal Title
  
  Cell Rep.
  
  Volume: 20 Issue: 9 Pages: 2116-2130
- DOI
  10.1016/j.celrep.2017.08.014
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07131, KAKENHI-PROJECT-17H01519, KAKENHI-PROJECT-17H04028
[Journal Article] Evaluation of Lecithinized Superoxide Dismutase for the Prevention of Acute Respiratory Distress Syndrome in Animal Models.2017
- Author(s)
  Tanaka KI, Tamura F, Sugizaki T, Kawahara M, Kuba K, Imai Y, Mizushima T
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 56 Pages: 179-190
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293050
[Journal Article] The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription2017
- Author(s)
  Rodriguez-Gil Alfonso、Ritter Olesja、Saul Vera V.、Wilhelm Jochen、Yang Chen-Yuan、Grosschedl Rudolf、Imai Yumiko、Kuba Keiji、Kracht Michael、Schmitz M. Lienhard
- Journal Title
  
  Scientific Reports
  
  Volume: 7(1) Issue: 1 Pages: 3547-3547
- DOI
  10.1038/s41598-017-03708-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19693, KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-17H06179
[Journal Article] Evaluation of Lecithinized Superoxide Dismutase for the Prevention of Acute Respiratory Distress Syndrome in Animal Models2017
- Author(s)
  Tanaka KI, Tamura F, Sugizaki T, Kawahara M, Kuba K, Imai Y, Mizushima T
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 56(2) Issue: 2 Pages: 179-190
- DOI
  10.1165/rcmb.2016-0158oc
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-26460177, KAKENHI-PROJECT-15K15304
[Journal Article] Vps34 regulates myofibril proteostasis to prevent hypertrophic cardiomyopathy.2017
- Author(s)
  Kimura H, Eguchi S, Sasaki J, Kuba K, Nakanishi H, Takasuga S, Yamazaki M, Goto A, Watanabe H, Itoh H, Imai Y, Suzuki A, Mizushima N, Sasaki T
- Journal Title
  
  JCI Insight
  
  Volume: 2 Issue: 1 Pages: 89462-89478
- DOI
  10.1172/jci.insight.89462
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05978, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26253083, KAKENHI-PROJECT-15H04693, KAKENHI-PROJECT-26293050, KAKENHI-PROJECT-26460059, KAKENHI-PROJECT-26461458, KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-15K15304, KAKENHI-PLANNED-25111005, KAKENHI-PROJECT-26440020, KAKENHI-PROJECT-26670132, KAKENHI-PROJECT-15K18857, KAKENHI-PROJECT-17H01400, KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-26640081, KAKENHI-PLANNED-15H05899, KAKENHI-PROJECT-17H03980
[Journal Article] Structure-activity relationship of cyclic pentapeptide malformins as fibrinolysis enhancers.2016
- Author(s)
  Koizumi Y, Nagai K, Hasumi K, Kuba K, Sugiyama T
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 26 Issue: 21 Pages: 5267-5271
- DOI
  10.1016/j.bmcl.2016.09.045
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293050, KAKENHI-PROJECT-26350969, KAKENHI-PROJECT-15K15304
[Journal Article] Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis.2016
- Author(s)
  Yang CY, Ramamoorthy S, Boller S, Rosenbaum M, Rodriguez Gil A, Mittler G, Imai Y, Kuba K, Grosschedl R
- Journal Title
  
  Genes Dev
  
  Volume: 30 Pages: 2310-2324
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15304
[Journal Article] Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis.2016
- Author(s)
  Yang CY, Ramamoorthy S, Boller S, Rosenbaum M, Rodriguez Gil A, Mittler G, Imai Y, Kuba K, Grosschedl R
- Journal Title
  
  Genes & Development
  
  Volume: 30 Pages: 2310-2324
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293050
[Journal Article] Cationic nanoparticles directly bind angiotensin-converting enzyme 2 and induce acute lung injury in mice.2015
- Author(s)
  Sun Y, Kuba K, et al.
- Journal Title
  
  Part Fibre Toxicol.
  
  Volume: 12 Pages: 4-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293050
[Journal Article] Cationic nanoparticles directly bind angiotensin-converting enzyme 2 and induce acute lung injury in mice.2015
- Author(s)
  Sun Y, Kuba K, Jiang C, et al.（23著者、13番目）
- Journal Title
  
  Part Fibre Toxicol
  
  Volume: 12 Issue: 1
- DOI
  10.1186/s12989-015-0080-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293050
[Journal Article] Cationic nanoparticles directly bind angiotensin-converting enzyme 2 and induce acute lung injury in mice.2015
- Author(s)
  Sun Y, Kuba K, et al.
- Journal Title
  
  Part Fibre Toxicol.
  
  Volume: 12 Pages: 4-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15304
[Journal Article] The arachidonic acid metabolome as conserved regulator of cholesterol metabolism.2014
- Author(s)
  Demetz E, Schroll A, Auer K, Heim C, Patsch JR, Eller P, Theurl M, Lener D, Stanzl U, Seifert M, Haschka D, Asshoff M, Dichtl S, Nairz M, Huber E, Stadlinger M, Li X, Pallweber P, Scharnagl H, Stojakovic T, Marz W, Kleber ME, Garlaschelli K, Uboldi P, Catapano AL, Kuba K, Imai Y, Arita M, Tancevski I.
- Journal Title
  
  Cell Metab.
  
  Volume: 20 Issue: 5 Pages: 787-798
- DOI
  10.1016/j.cmet.2014.09.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116006, KAKENHI-PROJECT-26293050
[Journal Article] Aglobal in vivo Drosophila RNAi screen identifies NOT3 as aconserved regulator of heart function.2010
- Author(s)
  Neely G, Kuba K, et al.
- Journal Title
  
  Cell
  
  Volume: 141 Pages: 142-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390155
[Journal Article] 種間で保存された心機能調節因子NOT3の大規模in vivoショウジョウバエRNAiスクリーニングによる同定2010
- Author(s)
  久場敬司, 他
- Journal Title
  
  細胞工学
  
  Volume: 29 Pages: 592-593
- Data Source
  KAKENHI-PROJECT-21659198
[Journal Article] Inhibition of endostatin/collagen XVIII deteriorates left ventricular remodeling and heart failure in rat myocardial infarction model.2010
- Author(s)
  Isobe K, Kuba K, Isobe M, et al.
- Journal Title
  
  Circ.J 74(1)
  
  Pages: 109-119
- NAID
  10025941400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659198
[Journal Article] Trilogy of ACE2:Apeptidase in the renin-angiotensin system, a SARS receptor, and a partner for amino acid transporters.2010
- Author(s)
  Kuba K, et al.
- Journal Title
  
  Pharmacol.Ther.
  
  Volume: 128 Pages: 119-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390155
[Journal Article] 種間で保存された心機能調節因子NOT3の大規模in vivoショウジョウバエRNAiスクリーニングによる同定2010
- Author(s)
  久場敬司, 他
- Journal Title
  
  細胞工学
  
  Volume: 29 Pages: 592-593
- Data Source
  KAKENHI-PROJECT-22390155
[Journal Article] PI3K gamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway.2010
- Author(s)
  Haubner BJ, Kuba K, Imai Y, et al.
- Journal Title
  
  PLoS One. 5(2)
  
  Pages: 9350-9357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659198
[Journal Article] Trilogy of ACE2 : A peptidase in the renin-angiotensin system, a SARS receptor, and a partner for amino acid transporters.2010
- Author(s)
  Kuba K, et al.
- Journal Title
  
  Pharmacol.Ther.
  
  Volume: 128 Pages: 119-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659198
[Journal Article] A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.2010
- Author(s)
  Neely G, Kuba K, et al.
- Journal Title
  
  Cell
  
  Volume: 141 Pages: 142-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659198
[Journal Article] Orphan Transporter SLC6A18 Is Renal Neutral Amino Acid Transporter B0AT32009
- Author(s)
  Singer D, Kuba K, et al.
- Journal Title
  
  J Biol Chem. 284(30)
  
  Pages: 19953-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659198
[Journal Article] Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations2009
- Author(s)
  Camargo S, Kuba K, et.al.
- Journal Title
  
  Gastroenterology 136(3)
  
  Pages: 872-882
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] The role of ACE2 in pulmonary diseases--relevance for the nephrologist2009
- Author(s)
  Oudit GY, Kuba K, et.al.
- Journal Title
  
  Nephrol Dial Transplant 24(5)
  
  Pages: 1362-1365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] Tissue-specificamino acid transporter partners ACE2 and Collectrin differentially interact with Hartnupmutations2008
- Author(s)
  Camargo SM, Kuba K, et.al.
- Journal Title
  
  Gastroenterology
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] Identification ofoxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury2008
- Author(s)
  Imai Y, Kuba K, et.al.
- Journal Title
  
  Cell 133(2)
  
  Pages: 235-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] The discoveryof ACE2 and its role in acute lung injury2008
- Author(s)
  Penninger J, Imai Y, Kuba K
- Journal Title
  
  ExpPhysiol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] Thediscovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice2008
- Author(s)
  Imai Y, Kuba K, Penninger JM
- Journal Title
  
  ExpPhysiol 93(5)
  
  Pages: 543-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] Identification of oxidative stress and toll like receptor 4 signaling as a key pathway of acute lung injury2008
- Author(s)
  Imai Y, Kuba K, et.al.
- Journal Title
  
  Cell 18 ; 133(2)
  
  Pages: 235-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] ACE2の疾患病態発症における役割2008
- Author(s)
  久場敬司、今井由美子、木村彰方
- Journal Title
  
  医学のあゆみ Vol.226, No.11
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] Toll様受容体4-TRIFを介した過剰免疫はH5N1インフルエンザウイルスによる呼吸不全を重症化させる2008
- Author(s)
  今井由美子、久場敬司、Penninger JM.
- Journal Title
  
  細胞工学 27(7)
  
  Pages: 696-97
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] Lessonsfrom SARS a new potential therapy for acuterespiratory distress syndrome (ARDS) withangiotensin converting enzyme 2 (ACE2)]2008
- Author(s)
  Imai Y, Kuba K, Penninger JM
- Journal Title
  
  Masui 57(3)
  
  Pages: 302-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] Renin angiotensin system and acute respiratory distress syndrome (ARDS)2007
- Author(s)
  Imai Y, Kuba K, Penninger JM
- Journal Title
  
  Drug Discovery Today 3
  
  Pages: 225-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload2007
- Author(s)
  Kuba K, et. al.(30著者、1番目)
- Journal Title
  
  Circulation Research 101(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] Angiotensin-converting enzyme 2 in acuterespiratory distress syndromeal.2007
- Author(s)
  Imai Y, Kuba K, Penninger JM
- Journal Title
  
  Cell Mol Life Sci 64(15)
  
  Pages: 2006-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Journal Article] Impaired heartcontractility in Apelin gene-deficient miceassociated with aging and pressure overload2007
- Author(s)
  Kuba K, Kimura A, et.al.
- Journal Title
  
  Circ Res 101(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890062
[Patent] Galectin-7阻害剤を用いた癌転移抑制剤2022
- Inventor(s)
  久場敬司、本山悟、安健博、鈴木穣
- Industrial Property Rights Holder
  久場敬司、本山悟、安健博、鈴木穣
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K19551
[Patent] Galectin-7阻害剤を用いた癌転移抑制剤2022
- Inventor(s)
  久場敬司、本山悟、安健博、鈴木穣
- Industrial Property Rights Holder
  秋田大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K06907
[Patent] 原核微生物由来ポリペプチドを含有する肺損傷および障害を処置または予防するための医薬組成物2020
- Inventor(s)
  久場敬司、今井由美子
- Industrial Property Rights Holder
  秋田大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K21566
[Patent] 原核微生物由来ポリペプチドを含有する肺損傷および障害を処置または予防するための医薬組成物2020
- Inventor(s)
  久場敬司、今井由美子
- Industrial Property Rights Holder
  秋田大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20H03426
[Patent] アンジオテンシン変換酵素２活性を有する原核微生物由来ポリペプチドの医薬用途2020
- Inventor(s)
  久場敬司
- Industrial Property Rights Holder
  久場敬司
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] RNA 制御を介したストレス応答と生体恒常性維持機構2023
- Author(s)
  久場敬司
- Organizer
  レドックスR&D戦略委員会・春のシンポジウム
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] 扁平上皮癌の不均一性における免疫抑制の微小環境は高転移性細胞の発生をもたらす2023
- Author(s)
  長岐雄志、安健博、本山悟、山口智和、星崎みどり、煙山紘平、鈴木穣、今井由美子、南谷佳弘、久場敬司
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K06907
[Presentation] Immunosuppression-elicited Galectin-7 is a crucial metastatic enhancer of squamous cell carcinoma2022
- Author(s)
  Jianbo An，Yushi Nagaki，Midori Hoshizaki，Tomokazu Yamaguchi，Yuta Kuze，Yumiko Imai，Satoru Motoyama，Yutaka Suzuki，Keiji Kuba
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06907
[Presentation] 心不全におけるRNA制御メカニズム2022
- Author(s)
  久場敬司
- Organizer
  第174回日本循環器学会東北地方会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] Upregulation of Galectin-7 in specific tumor microenvironment contributes to squamous cell carcinoma metastasis2022
- Author(s)
  Jianbo An，Yushi Nagaki，Midori Hoshizaki，Tomokazu Yamaguchi，Yuta Kuze，Yumiko Imai，Satoru Motoyama，Yutaka Suzuki，Keiji Kuba
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06907
[Presentation] Physiological roles of CCR4-NOT complex and CNOT4 in neuronal homeostasis2022
- Author(s)
  Tomokazu Yamaguchi, Keiji Kuba
- Organizer
  The 9th CCR4-NOT Meeting
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] 特異的がん微小環境にて誘導されるGalectin-7は扁平上皮癌の転移促進因子である2022
- Author(s)
  安健博、長岐雄志、星崎みどり、山口智和、久世裕太、今井由美子、本山悟、　鈴木穣、久場敬司
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K19551
[Presentation] Immunosuppression-elicited Galectin-7 is a crucial metastatic enhancer of squamous cell carcinoma2022
- Author(s)
  Jianbo An, Yushi Nagaki, Midori Hoshizaki, Tomokazu Yamaguchi, Yuta Kuze, Yumiko Imai, Satoru Motoyama, Yutaka Suzuki, Keiji Kuba
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19551
[Presentation] ACE2-like carboxypeptidase B38-CAP suppresses severe acute lung injury induced by aspiration pneumonia and abdominal sepsis as well as SARS-CoV-2 infection2022
- Author(s)
  Tomokazu Yamaguchi, Takafumi Minato, Midori Hoshizaki, Satoru Nirasawa, Jianbo An, Saori Takahashi, Josef M. Penninger, Yumiko Imai, Keiji Kuba
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] 扁平上皮癌に由来する新たな転移誘導因子Galectin-7の同定2022
- Author(s)
  安健博、長岐雄志、星崎みどり、山口智和、久世裕太、今井由美子、本山悟、鈴木穣、久場敬司
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06907
[Presentation] Dissecting the roles of CCR4-NOT complex and CNOT4 in maintaining tissue homeostasis2022
- Author(s)
  Tomokazu Yamaguchi, Midori Hoshizaki, Jianbo An, Yukio Kawahara, Yutaka Suzuki, Yumiko Imai, Toshifumi Inada, Tadashi Yamamoto, Keiji Kuba
- Organizer
  第23回日本RNA学会
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] Suppression of SARS-CoV-2-induced lung injury by ACE2-like carboxypeptidase B38-CAP in COVID-19 mouse model2021
- Author(s)
  Tomokazu Yamaguchi, Takafumi Minato, Midori Hoshizaki, Masamitsu N Asaka, Satoru Nirasawa, Mayumi Niiyama, Masaki Imai, Saori Takahashi, Daichi Utsumi, Jianbo An, Satoshi Nagata, Haruhiko Kamada, Yoshihiro Kawaoka, Yasuhiro Yasutomi, Yumiko Imai, Keiji Kuba
- Organizer
  第94回日本薬理学会
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] Dissecting CCR4-NOT complex-mediated mRNA control in cardiac pathology/physiology and beyond2021
- Author(s)
  久場敬司
- Organizer
  RIKEN IMS seminar
- Invited
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] CCR4-NOT Deadenylase Complex Controls the Expression of Autophagy Genes and Prevents Atg7-Dependent Cell Death in the Heart2021
- Author(s)
  山口智和, 鈴木享, 佐藤輝紀, 高橋明格, 山本雅, 今井由美子, 久場敬司
- Organizer
  第85回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21566
[Presentation] ACE2酵素活性による COVID-19 急性肺傷害の治療2021
- Author(s)
  久場敬司
- Organizer
  第94回日本生化学会大会シンポジウム1S10e
- Data Source
  KAKENHI-PROJECT-20K21566
[Presentation] ACE2酵素活性によるCOVID-19急性肺傷害の治療2021
- Author(s)
  久場敬司
- Organizer
  第5回理論免疫学ワークショップ
- Data Source
  KAKENHI-PROJECT-20K21566
[Presentation] ACE2酵素活性によるCOVID-19急性肺傷害の治療2021
- Author(s)
  久場敬司
- Organizer
  第5回理論免疫学ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] ACE2酵素活性による COVID-19 急性肺傷害の治療2021
- Author(s)
  久場敬司
- Organizer
  第94回日本生化学会大会シンポジウム1S10e
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] ACE2酵素B38-CAPの循環呼吸器疾患への治療応用2021
- Author(s)
  久場敬司
- Organizer
  創薬薬理フォーラム第69回談話会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] CCR4-NOT Deadenylase Complex Controls the Expression of Autophagy Genes and Prevents Atg7-Dependent Cell Death in the Heart2021
- Author(s)
  山口智和, 鈴木享, 佐藤輝紀, 高橋明格, 山本雅, 今井由美子, 久場敬司
- Organizer
  第85回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] 循環器疾患におけるCCR4-NOT複合体によるRNA制御ネットワークの解析2021
- Author(s)
  久場敬司
- Organizer
  第44回日本分子生物学会年会ワークショップ3AW-07
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] COVID-19のARDS/急性肺傷害に対するACE2酵素活性の治療効果2021
- Author(s)
  久場敬司
- Organizer
  第１７回霊長類医科学フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] Suppression of SARS-CoV-2-induced lung injury by ACE2-like carboxypeptidase B38-CAP in COVID-19 mouse model2021
- Author(s)
  Tomokazu Yamaguchi, Takafumi Minato, Midori Hoshizaki, Masamitsu N Asaka, Satoru Nirasawa, Mayumi Niiyama, Masaki Imai, Saori Takahashi, Daichi Utsumi, Jianbo An, Satoshi Nagata, Haruhiko Kamada, Yoshihiro Kawaoka, Yasuhiro Yasutomi, Yumiko Imai, Keiji Kuba
- Organizer
  第94回日本薬理学会
- Data Source
  KAKENHI-PROJECT-20K21566
[Presentation] 心不全におけるmRNA代謝の制御機構2021
- Author(s)
  久場敬司
- Organizer
  第25回日本心不全学会学術集会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] ACE2酵素B38-CAPの循環呼吸器疾患への治療応用2021
- Author(s)
  久場敬司
- Organizer
  創薬薬理フォーラム第69回談話会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21566
[Presentation] COVID-19のARDS/急性肺傷害に対するACE2酵素活性の治療効果2021
- Author(s)
  久場敬司
- Organizer
  第１７回霊長類医科学フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-20K21566
[Presentation] MRTF-Aはマクロファージ機能を制御して動脈硬化形成に関わる2020
- Author(s)
  安健博，成瀬妙子，日野原邦彦，副島友莉恵，沢辺元司，中川靖章，桑原宏一郎，久場敬司，木村彰方
- Organizer
  第71回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] ｍ6A脱メチル化酵素ALKBH5は食道扁平上皮癌の細胞増殖を促進する予後不良因子である2020
- Author(s)
  長岐雄志，本山悟，山口智和，星崎みどり，佐藤雄亮，脇田晃行，川北雄太，南條博，南谷佳弘，久場敬司
- Organizer
  第120回日本外科学会
- Data Source
  KAKENHI-PROJECT-20K09048
[Presentation] 微生物由来のACE2様酵素B38-CAPはマウスにおける心臓のリモデリングと機能不全を改善する2020
- Author(s)
  湊隆文, 山口智和, 佐藤輝紀, 韮澤悟, 今井由美子, 高橋砂織, 渡邊博之, 久場敬司
- Organizer
  第71回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] 微生物由来のACE2様酵素B38-CAPはマウスにおける心臓のリモデリングと機能不全を改善する2020
- Author(s)
  湊隆文, 山口智和, 佐藤輝紀, 韮澤悟, 今井由美子, 高橋砂織, 渡邊博之, 久場敬司
- Organizer
  第71回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-20K21566
[Presentation] Identification of B38-CAP as an ACE2-like enzyme to suppress hypertension and cardiac dysfunction in mice2020
- Author(s)
  Keiji Kuba, Takafumi Minato, Satoru Nirasawa, Teruki Sato, Tomokazu Yamaguchi, Hiroyuki Watanabe, Yumiko Imai, Saori Takahashi
- Organizer
  第93回日本薬理学会年会（紙上開催）
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] m6A demethylase ALKBH5 promotes proliferation of esophageal squamous cell carcinoma associated with poor prognosis.2020
- Author(s)
  Yushi Nagaki, Keiji Kuba
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-20K21566
[Presentation] MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages2020
- Author(s)
  Jianbo An，Taeko Naruse，Kunihiko Hinohara，Yurie Soejima，Motoji Sawabe，Yasuaki Nakagawa，Koichiro Kuwahara，Keiji Kuba，Akinori Kimura
- Organizer
  第93回日本薬理学会年会（紙上開催）
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] 呼吸循環器疾患とRNA制御因子2020
- Author(s)
  久場敬司
- Organizer
  Cardiology Research & Clinical seminar
- Data Source
  KAKENHI-PROJECT-20K21566
[Presentation] MRTF-Aはマクロファージ機能を制御して動脈硬化形成に関わる2020
- Author(s)
  安健博、成瀬妙子、日野原邦彦、副島友莉恵、沢辺元司、中川靖章、桑原宏一郎、久場敬司、木村彰方
- Organizer
  日本生化学会東北支部第86回例会
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] 呼吸循環器疾患とRNA制御因子2020
- Author(s)
  久場敬司
- Organizer
  Cardiology Research & Clinical seminar
- Invited
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] Dissecting the role of CNOT6L deadenylase in pressure overload-induced cardiac fibrosis2020
- Author(s)
  山口智和、佐藤輝紀、湊隆文、安健博、星崎みどり、渡邊博之、今井由美子、山本雅、久場敬司
- Organizer
  第93回日本薬理学会年会（紙上開催）
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] m6A demethylase ALKBH5 promotes proliferation of esophageal squamous cell carcinoma associated with poor prognosis.2020
- Author(s)
  Yushi Nagaki, Keiji Kuba
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] B38-CAP is a bacteria-derived carboxypeptidase which resembles SARS-CoV-2 receptor ACE2 enzyme activity and suppresses hypertension and cardiac dysfunction in mice2020
- Author(s)
  Teruki Sato, Takafumi Minato, Satoru Nirasawa, Tomokazu Yamaguchi, Hiroyuki Watanabe, Yumiko Imai, Saori Takahashi, Keiji Kuba
- Organizer
  NIPS International meeting, HOLISTIC UNDERSTANDING OF CARDIOVASCULAR SYSTEM BY MECHANISTIC ANALYSIS OF PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03426
[Presentation] B38-CAP is a bacteria-derived carboxypeptidase which resembles SARS-CoV-2 receptor ACE2 enzyme activity and suppresses hypertension and cardiac dysfunction in mice2020
- Author(s)
  Teruki Sato, Takafumi Minato, Satoru Nirasawa, Tomokazu Yamaguchi, Hiroyuki Watanabe, Yumiko Imai, Saori Takahashi, Keiji Kuba
- Organizer
  NIPS International meeting, HOLISTIC UNDERSTANDING OF CARDIOVASCULAR SYSTEM BY MECHANISTIC ANALYSIS OF PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21566
[Presentation] 後天性赤芽球癆における骨髄性腫瘍関連遺伝子の体細胞変異に関する研究（PRCA-NGS2017）2019
- Author(s)
  幸丸純貴,小代田宗一,久場敬二,藤島直仁,嵯峨知生,面川　歩,植木重治,石田文宏,中尾眞二,松田　晃,太田晶子,通山　薫,鈴木隆二,三谷絹子,廣川　誠
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08856
[Presentation] mRNA poly(A)制御の破綻による循環器疾患の病態発現機構の解明2019
- Author(s)
  久場　敬司
- Organizer
  第42回日本分子生物学会年会ワークショップ3AW-08「ＲＮＡ制御と疾患」
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] RNA制御の破綻による循環器疾患の病態発現機構2019
- Author(s)
  久場　敬司
- Organizer
  第29回日本循環薬理学会・第55回高血圧関連疾患モデル学会合同学会シンポジウム
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] 細胞増殖制御におけるユビキチン転移酵素CNOT4の機能解析2019
- Author(s)
  山口智和、久場敬司
- Organizer
  第7回 CCR4-NOT研究会
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] RNA制御による循環機能調節の分子機構2019
- Author(s)
  久場敬司
- Organizer
  第22回京都心血管代謝セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] MRTF-Aはマクロファージ機能を制御して動脈硬化形成に関わる2019
- Author(s)
  安　健博，成瀬　妙子，日野原　邦彦，副島　友莉恵，沢辺　元司，中川　靖章，桑原　宏一郎，久場　敬司，木村　彰方
- Organizer
  第29回日本循環薬理学会・第55回高血圧関連疾患モデル学会合同学会
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] CCR4-NOT複合体を介したRNA制御による生体恒常性維持機構2019
- Author(s)
  久場敬司
- Organizer
  第3回理論免疫学ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] 心臓リモデリングにおける CCR4-NOT deadenylaseの機能解析2019
- Author(s)
  安健博、佐藤輝紀、湊隆文、山口智和、星崎みどり、夏井美幸、渡邊博之、今井由美子、山本雅、久場敬司
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] 単球/マクロファージ活性化制御における CNOT3の役割・機能の解析2019
- Author(s)
  安健博、久場敬司
- Organizer
  第7回 CCR4-NOT研究会
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] mRNA deadenylation-mediated control of cardiac homeostasis2019
- Author(s)
  Keiji Kuba
- Organizer
  The 50th NIPS International Symposium ‘MIRACLES’ in Cardiovascular Physiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] CCR4-NOT脱アデニル化因子による心臓リモデリング抑制作用の解析2019
- Author(s)
  山口智和、佐藤輝紀、湊隆文、安健博、星崎みどり、渡邊博之、今井由美子、山本雅、久場敬司
- Organizer
  第29回日本循環薬理学会・第55回高血圧関連疾患モデル学会合同学会
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] 肥満組織におけるCNOT4ユビキチンリガーゼの生理機能解析2019
- Author(s)
  山口智和、佐藤輝紀、星崎みどり、山本雅、今井由美子、久場敬司
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] RNA 制御を介した心機能の恒常性維持機構の解明2019
- Author(s)
  久場敬司
- Organizer
  Research PlaNet 2019
- Invited
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] CCR4-NOT脱アデニル化酵素複合体による心機能制御機構の解明2018
- Author(s)
  山口智和, 鈴木享, 佐藤輝紀, 高橋明格, 山本雅, 今井由美子, 久場敬司
- Organizer
  第20回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] A bacteria-derived ACE2-like enzyme suppresses cardiac remodeling and dysfunction in mice.2018
- Author(s)
  湊隆文, 韮澤悟, 佐藤輝紀, 小澤諒, 高橋砂織, 渡邊博之, 久場敬司
- Organizer
  第2回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] 微生物由来のアンジオテンシン変換酵素2（ACE2）様酵素による心臓リモデリング・機能不全の改善2018
- Author(s)
  久場敬司, 佐藤輝紀, 湊隆文, 韮澤悟, 小澤諒, 山口智和, 中原和彦, 渡邊博之, 今井由美子,高橋砂織
- Organizer
  生理学研究所研究会
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] 貧食細胞由来のNPYとそのY1受容体の重症インフルエンザの病態における役割（Phagocytes-derives NPY and Y1 receptor axis controls the pathology of severe influenza virus infection）2018
- Author(s)
  星崎みどり、藤原誠樹、市田悠、丹下喜恵、黒田悦史、石井健、久場敬司、今井由美子
- Organizer
  第11回次世代アジュバント研究会
- Data Source
  KAKENHI-PROJECT-17H06179
[Presentation] CCR4-NOT脱アデニル化酵素複合体によるAtg7依存性細胞死の阻害と心機能改善作用2018
- Author(s)
  山口智和, 鈴木享, 佐藤輝紀, 高橋明格, 門脇歩美, 夏井美幸, 小泉幸央, 山本雅, 今井由美子, 久場敬司
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] 心臓の恒常性維持における分子ネットワークとシステム連関2018
- Author(s)
  久場敬司
- Organizer
  第83回秋田県医学会総会・秋田県医師会設立71周年記念医学大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] 心不全病態における新規APJリガンドELABELAの機能的意義の解明2017
- Author(s)
  佐藤輝紀、山口智和、渡邊博之、門脇歩美、佐藤チトセ、伊藤宏、今井由美子、久場敬司
- Organizer
  第68回薬理学会北部会
- Data Source
  KAKENHI-PROJECT-16K19013
[Presentation] 新規心不全治療標的としてのApelin/ELABELA -APJ受容体システム2017
- Author(s)
  佐藤輝紀、渡邊博之、伊藤宏、久場敬司
- Organizer
  第21回日本心不全学会学術集会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K19013
[Presentation] 新規APJリガンドELABELAは圧負荷やアンジオテンシンIIによる心臓リモデリングを抑制する2017
- Author(s)
  佐藤輝紀, 渡邊博之,山口智和,木村彰方, 深水昭吉, Josef PENNINGER, Reversade BRUNO, 伊藤宏, 今井由美子, 久場敬司
- Organizer
  第21回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19013
[Presentation] 心不全病態におけるRNA分解制御の新しい生理的意義2017
- Author(s)
  久場敬司
- Organizer
  日本薬理学会　シンポジウム
- Place of Presentation
  長崎
- Invited
- Data Source
  KAKENHI-PROJECT-15K15304
[Presentation] RNA deadenylation-guided control of cardiac homeostasis.2017
- Author(s)
  Kuba K
- Organizer
  Cutting Edge Developments in RNA Biology for the Control of Gene Expression.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] mRNA deadenylation-guided regulation of cardiac homeostasis2017
- Author(s)
  久場敬司
- Organizer
  理化学研究所IMS疾患生物学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] New aspects of RNA decay in controlling heart function2017
- Author(s)
  久場敬司
- Organizer
  富山大学大学院特別セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] 心不全病態におけるRNA分解制御の新しい生理的意義2017
- Author(s)
  久場敬司
- Organizer
  第90回日本薬理学会シンポジウム３
- Place of Presentation
  長崎
- Invited
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] 心不全病態におけるRNA分解制御の新しい生理的意義2017
- Author(s)
  久場敬司
- Organizer
  第21回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04028
[Presentation] CCR4-NOT complex controls adenine nucleotide metabolism and energy sensing in cardiac homeostasis2016
- Author(s)
  久場敬司
- Organizer
  The 89th JBS meeting symposium 3S17
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] RNA代謝制御による心機能の恒常性維持2016
- Author(s)
  久場敬司
- Organizer
  第10回京阪神心不全研究会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] RNA分解による心臓エネルギー代謝の恒常性維持2016
- Author(s)
  久場敬司
- Organizer
  第4回 CCR4-NOT研究会
- Place of Presentation
  秋田
- Year and Date
  2016-02-12
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] Dissecting the functional role of A Novel APJ ligand, ELABELA, in heart failure2016
- Author(s)
  佐藤輝紀、久場敬司
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K15304
[Presentation] 心臓のmRNA poly(A)分解とエネルギー感知シグナルの相互作用機構の解明2016
- Author(s)
  山口智和、鈴木享、佐藤輝紀、夏井美幸、門脇歩美、佐藤チトセ、小泉幸央、高橋明格、山本雅、今井由美子、久場敬司
- Organizer
  第26回日本循環薬理学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] CCR4-NOT complex controls adenine nucleotide metabolism and energy sensing in cardiac homeostasis2016
- Author(s)
  久場敬司
- Organizer
  日本生化学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-15K15304
[Presentation] 発生期Apelin受容体リガンドElabelaによる心機能調節とRAS系制御2016
- Author(s)
  久場敬司
- Organizer
  第２回血管生理学セミナー
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-15K15304
[Presentation] Dissecting the functional role of A Novel APJ ligand, ELABELA, in heart failure2016
- Author(s)
  佐藤輝紀、久場敬司
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] 心不全病態における新規APJリガンドELABELAの機能的意義の解明2016
- Author(s)
  佐藤輝紀, 山口智和, 渡邊博之, 門脇歩美, 佐藤チトセ, 伊藤宏, 今井由美子, 久場敬司
- Organizer
  第26回日本循環薬理学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] 心不全病態における新規APJリガンドELABELAの機能的意義の解明2016
- Author(s)
  佐藤輝紀, 山口智和, 渡邊博之, 門脇歩美, 佐藤チトセ, 伊藤宏, 今井由美子, 久場敬司
- Organizer
  日本循環薬理学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-15K15304
[Presentation] 心不全病態における新規APJリガンドELABELAの機能的意義の解明2016
- Author(s)
  佐藤輝紀、山口智和、渡邊博之、門脇歩美、佐藤チトセ、伊藤宏、今井由美子、久場敬司
- Organizer
  循環薬理学会
- Place of Presentation
  信州大学医学部附属病院大会議室
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-16K19013
[Presentation] Signaling network to maintain cardiac homeostasis in failing hearts2015
- Author(s)
  久場敬司
- Organizer
  The 4th Hsien Wu and Ray Wu Symposia “Proteins, Genes and Diseases”
- Place of Presentation
  北京
- Year and Date
  2015-08-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] Signaling network to maintain cardiac homeostasis in failing hearts2015
- Author(s)
  久場敬司
- Organizer
  The 4th Hsien Wu and Ray Wu Symposia “Proteins, Genes and Diseases”
- Place of Presentation
  北京
- Year and Date
  2015-08-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15304
[Presentation] 心臓における新規Apelin受容体リガンドApelaの機能的意義の解析2015
- Author(s)
  久場敬司
- Organizer
  生理学研究所研究会 2015　「心臓・血管系の包括的な機能統合研究」
- Place of Presentation
  岡崎
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-15K15304
[Presentation] 心臓における新規Apelin受容体リガンドApelaの機能的意義の解析2015
- Author(s)
  久場敬司
- Organizer
  生理学研究所研究会 2015　「心臓・血管系の包括的な機能統合研究」
- Place of Presentation
  岡崎
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] Angiotensin converting enzyme 2 (ACE2) links Apelin and angiotensin systems in controlling heart function.2015
- Author(s)
  久場敬司
- Organizer
  日本解剖学会・日本生理学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] 心臓のmRNA分解とエネルギー代謝の恒常性維持2015
- Author(s)
  久場敬司
- Organizer
  第2回仙台先進循環器研究会
- Place of Presentation
  仙台
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] CCR4-NOT複合体によるアデニン核酸制御機構の解析2015
- Author(s)
  山口智和、久場敬司
- Organizer
  RNA学会
- Place of Presentation
  札幌
- Year and Date
  2015-07-13
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] アンジオテンシン変換酵素２（ACE2）の多彩な生理機能と制御機構の解明2015
- Author(s)
  久場敬司
- Organizer
  第160回日本循環器学会東北地方会
- Place of Presentation
  盛岡
- Year and Date
  2015-04-10
- Invited
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] CNOT3を介した心臓のアデニン核酸制御機構の解析2015
- Author(s)
  山口智和、久場敬司
- Organizer
  第66回日本薬理学会北部会
- Place of Presentation
  富山
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] RNA分解制御による心臓エネルギー恒常性維持の分子機構2015
- Author(s)
  久場敬司
- Organizer
  BMB2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] mRNA分解制御を介した心臓の恒常性維持2015
- Author(s)
  久場敬司
- Organizer
  第一回 J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] Dissecting the mechanisms for regulation of cardiac energy metabolism by CCR4-NOT complex2014
- Author(s)
  久場敬司
- Organizer
  第 16 回日本RNA学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-07-23
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] CCR4-NOT deadenylase complex links mRNA metabolism to energy sensing in cardiac homeostasis2014
- Author(s)
  久場敬司
- Organizer
  第 31 回国際心臓研究学会（ISHR）日本部会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] 酵母からヒトまで保存されたCCR4-NOT複合体による心機能制御メカニズム2014
- Author(s)
  久場敬司
- Organizer
  第24回日本循環薬理学会
- Place of Presentation
  山形
- Year and Date
  2014-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] Genome-wideショウジョウバエスクリーニングによる新規の心機能調節遺伝子の単離2010
- Author(s)
  久場敬司
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪市
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21659198
[Presentation] ゲノムワイドRNAiスクリーニングによる心機能調節因子NOT3の同定2010
- Author(s)
  久場敬司
- Organizer
  第20回日本循環薬理学会
- Place of Presentation
  札幌市
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21659198
[Presentation] CNOT3はショウジョウバエからマウス、ヒトまで保存された新規の心機能調節因子である。2010
- Author(s)
  久場敬司
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22390155
[Presentation] ゲノムワイドRNAiスクリーニングによる心機能調節因子NOT3の同定2010
- Author(s)
  久場敬司
- Organizer
  第20回日本循環薬理学会
- Place of Presentation
  札幌市
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-22390155
[Presentation] CNOT3はショウジョウバエからマウス、ヒトまで保存された新規の心機能調節因子である2010
- Author(s)
  久場敬司
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21659198
[Presentation] アンジオテンシン変換酵素2(ACE2)-apelinによる循環機能調節2009
- Author(s)
  久場敬司
- Organizer
  生理研研究会
- Place of Presentation
  愛知県、岡崎市
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-21659198
[Presentation] アンジオテンシン変換酵素(ACE2)と心血管機能制御2008
- Author(s)
  久場敬司
- Organizer
  第12回Molecular Cardiocvascular conference
- Place of Presentation
  北海道、キロロ
- Year and Date
  2008-09-05
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] 疾患病態発症におけるACE2(アンジオテンシン変換酵素2)の役割2008
- Author(s)
  久場敬司
- Organizer
  第4回宮崎サイエンスキャンプ
- Place of Presentation
  ワールドコンベンションセンターサミット・宮崎
- Year and Date
  2008-02-15
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] アンジオテンシン変換酵素2(ACE2)によるARDS/急性肺傷害阻止のメカニズム2008
- Author(s)
  久場敬司
- Organizer
  第9回東京アンジオテンシン研究会
- Place of Presentation
  東京(経団連会館)
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] 11th Cardiovascular Genomicsand Atherosclerosis Symposium2008
- Author(s)
  久場敬司
- Organizer
  Angiotensin converting enzyme 2 and itsnew substrate Apelin in heart diseases
- Place of Presentation
  Seoul, Korea
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] Angiotensin converting enzyme 2 and itsnew substrate, Apelin2008
- Author(s)
  久場敬司
- Organizer
  MTT International Symposium
- Place of Presentation
  東京医科歯科大学、難治疾患研究所1階会議室
- Year and Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] アンジオテンシン変換酵素2(ACE2)の疾患病態発症における役割2008
- Author(s)
  久場敬司
- Organizer
  第6回宮崎生活習慣病研究会
- Place of Presentation
  宮崎観光ホテル、3階「緋耀の間」
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] 急性肺傷害の炎症におけるSARSレセプターACE2の役割2008
- Author(s)
  久場敬司
- Organizer
  メタボリックリサーチフォーラム
- Place of Presentation
  東京
- Year and Date
  2008-03-15
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] アンジオテンシン変換酵素(ACE2)と心血管機能制御2008
- Author(s)
  久場敬司
- Organizer
  第12回MolecularCardiocvascular conference
- Place of Presentation
  北海道キロロ、ホテルピアノ2階「キロロボールルーム・大」
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] 夏の研修旅行 : 研究三都物語、大阪、トロント、ウィーン2008
- Author(s)
  久場敬司
- Organizer
  深水昭吉研究室
- Place of Presentation
  和光純薬湯河原研修所、大会議室
- Year and Date
  2008-07-27
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] 新規生理活性物質アペリン遺伝子欠損マウスの心筋梗塞モデルにおける心機能障害の研究2008
- Author(s)
  久場敬司
- Organizer
  第13回アディポサイエンス研究会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] A critical role of Angiotensin converting enzyme 2 (ACE2) in severe acute lung injury2007
- Author(s)
  Kuba K, Imai Y, Uhlig S, Slutsky A, Penninger JM
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] 心機能維持におけるACE2の役割2007
- Author(s)
  久場敬司
- Organizer
  第8回アンジオテンシン研究会
- Place of Presentation
  東京、経団連会館ビル
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] Apelin playsa crucial role in maintaining heartcontractility in aging and pressureoverload2007
- Author(s)
  久場敬司
- Organizer
  第11回MolecularCardiocvascular Conference
- Place of Presentation
  北海道キロロ
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] Endogenous Apelin maintains heart contractility in aging and pressure overload2007
- Author(s)
  Kuba K, et. al.
- Organizer
  American Heart Association Scientific Session
- Place of Presentation
  Orlando, USA
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] A critical role of Angiotensinconverting enzyme 2(ACE2)in severe acutelung injury2007
- Author(s)
  久場敬司
- Organizer
  ATS International Conference2007
- Place of Presentation
  米国サンフランシスコ
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] SARSレセプターACE2によるARDS治療2007
- Author(s)
  久場敬司
- Organizer
  第38回血管研究会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] Endogenous Apelin maintains heartcontractility in aging and pressureoverload2007
- Author(s)
  久場敬司
- Organizer
  AHA Scientific Session 2007
- Place of Presentation
  米国オーランド
- Data Source
  KAKENHI-PROJECT-19890062
[Presentation] Dissecting the role of CCR4-NOT-associated ubiquitin converting enzyme in controlling heart functions.
- Author(s)
  山口智和、門脇歩美、小泉幸央、夏井美幸、佐藤チトセ、今井由美子、久場敬司
- Organizer
  第88回日本薬理学会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26293050
[Presentation] A crucial role of CNOT3 in stem cell proliferation and early embryonic development
- Author(s)
  小泉幸央、山口智和、門脇歩美、夏井美幸、佐藤チトセ、今井由美子、久場敬司
- Organizer
  第88回日本薬理学会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26293050

1. Imai Yumiko (50231163)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. Ebihara Takashi (20374407)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 立松恵 (70725605)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 高須賀俊輔 (90375262)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. KIMURA Akinori (60161551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. SATO Teruki (30733422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. Motoyama Satoru (60292372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 廣川誠 (50241667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 小松久美 (70646554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 石田文宏 (80311695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 安健博 (40723771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. 山口智和 (30749940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 石田純治

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 武谷三恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 佐々木雄彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 柳谷朗子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 鈴木亨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 有田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kuba Keiji 久場 敬司

Keiji Kuba 久場 敬司

KUBA Keiji 久場 敬司

Research Projects

Research Products

Co-Researchers

Elucidation of RNA-guided molecular networks in response to heart failure stressPrincipal Investigator

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免疫体質を規定するRNA代謝ネットワークの解析

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癌の転移・再発における細胞外Galectin-Xを介した免疫抑制機構の解明

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Spatial transcriptome analysis of highly metastatic tumours to develop new methods for the prediction and treatment of cancer metastasisPrincipal Investigator

Principal Investigator

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mRNA metabolism specific to ILC subsets

Principal Investigator

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RNA modification affecting lymph node metastasis in esophageal cancer

Principal Investigator

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Development of a bacteria-derived ACE2-like enzyme as a therapeutics for treating cardiovascular diseasesPrincipal Investigator

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Mechanistic insights into spatio-temporal regulation of RNA in cardio-metabolic diseasePrincipal Investigator

Principal Investigator

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後天性赤芽球癆における体細胞遺伝子変異の機能解明と新規治療基盤の開発

Principal Investigator

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RNA metabolism-based regulation of heart function and its application for treatment of heart failurePrincipal Investigator

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Identification of higher-order-epigenetic modification machineries and development of potential novel therapeutics in severe virus infection

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Dissecting the functional role of a novel ligand for APJ, ELABELA, in cardio-renal connection

Principal Investigator

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Research Institution

Application of genome editing and development-associated APJ ligand for exploring novel therapeutic candidates for heart failurePrincipal Investigator

Principal Investigator

Kuba Keiji 久場敬司

Keiji Kuba 久場敬司

KUBA Keiji 久場敬司