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Kuba Keiji  久場 敬司

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… Alternative Names

Keiji Kuba  久場 敬司

KUBA Keiji  久場 敬司

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Researcher Number 10451915
Other IDs
Affiliation (Current) 2020: 秋田大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2017 – 2020: 秋田大学, 医学系研究科, 教授
2017: 秋田大学, 大学院医学系研究科 分子機能学・代謝機能学講座, 教授
2014 – 2017: 秋田大学, 医学(系)研究科(研究院), 教授
2011: Akita University, 医学(系)研究科(研究院), 准教授
2009 – 2010: Akita University, 大学院・医学系研究科, 准教授
2008: Akita University, 医学部, 准教授
2007: Tokyo Medical and Dental University, 難治疾患研究所, 特任講師
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / General pharmacology / Pathological medical chemistry / Cardiovascular medicine / Basic Section 48030:Pharmacology-related / Medium-sized Section 52:General internal medicine and related fields
Except Principal Investigator
General pharmacology / Emergency medicine / Basic Section 55020:Digestive surgery-related / Basic Section 54010:Hematology and medical oncology-related
Keywords
Principal Investigator
心不全 / CCR4-NOT / CNOT3 / ACE2 / RNA / heart failure / Apelin / エピジェネティクス / 転写 / アンジオテンシン … More / SARS / ARDS / 急性肺傷害 / 酸化ストレス / Toll-like receptor 4 / 自然免疫 / 酸化リン脂質 / 高病原性インフルエンザ / H5N1 / ショウジョウバエ / QT時間 / deadenylase / デアデニレース / オートファジー / ネクローシス / RNA代謝 / 脱アデニル化 / 循環器 / RNA創薬 / 遺伝子改変マウス / CCR4-NOT / poly(A) / 心臓 / ELABELA / CRISPR/Cas9 / FoxM1 / ゲノム編集 / Elabela / CRISPR / deadenylation / ubiquitination / ace2 / translation / ATP / fibroblasts / transcription / nucleotide / Atg7 / cardiomyocyte / cell death / RNA分解 / エピトランスクリプトーム / 肥満 / 急性呼吸窮迫症候群 / 進化 / SARS-CoV-2 … More
Except Principal Investigator
ELABELA / APJ / 心不全 / 心腎連関 / 心保護効果 / レニンアンジオテンシン系 / 心肥大 / ウイルス感染 / ウイルス / リンパ節転移 / 固形癌 / エピトランスクリプトーム / 後天性赤芽球癆 / 再発・難治性 / 骨髄系腫瘍関連遺伝子 / 体細胞変異 / 免疫抑制療法 / 遺伝子変異 / 機能解析 / ゲノム編集 / 標的治療 Less
  • Research Projects

    (13 results)
  • Research Products

    (131 results)
  • Co-Researchers

    (36 People)
  •  Mechanistic insights into spatio-temporal regulation of RNA in cardio-metabolic diseasePrincipal InvestigatorOngoing

    • Principal Investigator
      久場 敬司
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Akita University
  •  食道癌リンパ節転移を支配する決定的なRNA修飾(エピトランスクリプトーム)の解明Ongoing

    • Principal Investigator
      本山 悟
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Akita University
  •  Development of a bacteria-derived ACE2-like enzyme as a therapeutics for treating cardiovascular diseasesPrincipal InvestigatorOngoing

    • Principal Investigator
      久場 敬司
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Akita University
  •  後天性赤芽球癆における体細胞遺伝子変異の機能解明と新規治療基盤の開発

    • Principal Investigator
      廣川 誠
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Akita University
  •  RNA metabolism-based regulation of heart function and its application for treatment of heart failurePrincipal Investigator

    • Principal Investigator
      Kuba Keiji
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Akita University
  •  Identification of higher-order-epigenetic modification machineries and development of potential novel therapeutics in severe virus infectionOngoing

    • Principal Investigator
      今井 由美子
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Emergency medicine
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Dissecting the functional role of a novel ligand for APJ, ELABELA, in cardio-renal connection

    • Principal Investigator
      SATO Teruki
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Akita University
  •  Application of genome editing and development-associated APJ ligand for exploring novel therapeutic candidates for heart failurePrincipal Investigator

    • Principal Investigator
      Keiji Kuba
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Akita University
  •  Mechanistic insight into CCR4-NOT deadenylase-mediated heart function control and its potential application for therapeuticsPrincipal Investigator

    • Principal Investigator
      Kuba Keiji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Akita University
  •  ヒト心疾患感受性遺伝子群の迅速な生体内機能解析法の開発Principal Investigator

    • Principal Investigator
      久場 敬司
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Akita University
  •  CCR4-NOT複合体による心機能制御の分子機構の解明研究Principal Investigator

    • Principal Investigator
      久場 敬司
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Akita University
  •  ショウジョウバエ、マウス、ヒト間で保存された疾患発症シグナルの解析研究Principal Investigator

    • Principal Investigator
      久場 敬司
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Akita University
  •  Dissecting the molecular mechanisms for SARS receptor ACE2-mediatedlung protection in ARDS/acute lung injuryPrincipal Investigator

    • Principal Investigator
      KUBA Keiji
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Akita University
      Tokyo Medical and Dental University

All 2020 2019 2018 2017 2016 2015 2014 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

  • [Book] Encyclopedia ofMolecular Mechanisms of Disease edited byFlorian Lang, Tubingen

    • Author(s)
      Kuba K, Imai Y, Penninger JM
    • Publisher
      Severe acuterespiratory distress syndrome(in press)
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] B38-CAP Is a Bacteria-Derived ACE2-like Enzyme That Suppresses Hypertension and Cardiac Dysfunction2020

    • Author(s)
      Minato T, Nirasawa S, Sato T, Yamaguchi T, Hoshizaki M, Inagaki T, Nakahara K, Yoshihashi T, Ozawa R, Yokota S, Natsui M, Koyota S, Yoshiya T, Yoshizawa-Kumagaye K, Motoyama S, Gotoh T, Nakaoka Y, Penninger JM, Watanabe H, Imai Y, Takahashi S, Kuba K
    • Journal Title

      Nature Communications

      Volume: 11(1) Pages: 1058-1058

    • DOI

      10.1038/s41467-020-14867-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-18K15038, KAKENHI-PROJECT-18K15879
  • [Journal Article] Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability2020

    • Author(s)
      Mostafa Dina、Takahashi Akinori、Yanagiya Akiko、Yamaguchi Tomokazu、Abe Takaya、Kureha Taku、Kuba Keiji、Kanegae Yumi、Furuta Yasuhide、Yamamoto Tadashi、Suzuki Toru
    • Journal Title

      RNA Biology

      Volume: 17 Pages: 403-416

    • DOI

      10.1080/15476286.2019.1709747

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06975, KAKENHI-PROJECT-18K07079, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-18K15038
  • [Journal Article] Genome-Scale CRISPR/Cas9 Screening Reveals SqualeneEpoxidase as a Susceptibility Factor for Cytotoxicity of Malformin A12019

    • Author(s)
      Koizumi Yukio、Fukushima Jun、Kobayashi Yayoi、Kadowaki Ayumi、Natsui Miyuki、Yamaguchi Tomokazu、Imai Yumiko、Sugiyama Toshihiro、Kuba Keiji
    • Journal Title

      Chembiochem

      Volume: 20 Pages: 1563-1568

    • DOI

      10.1002/cbic.201800769

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15038, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-17K19693, KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H06179
  • [Journal Article] Apelin and Elabela/Toddler; double ligands for APJ/Apelin receptor in heart development, physiology, and pathology2019

    • Author(s)
      Kuba K, Sato T, Imai Y, Yamaguchi T
    • Journal Title

      Peptides

      Volume: in press Pages: 62-70

    • DOI

      10.1016/j.peptides.2018.04.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K19013, KAKENHI-PROJECT-18K15038, KAKENHI-PROJECT-18K15879, KAKENHI-PROJECT-17H04028
  • [Journal Article] Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection2019

    • Author(s)
      Fujiwara S., Hoshizaki M., Ichida Y., Lex D., Kuroda E., Ishii KJ., Magi S., Okada M., Takao H., Gando M., Imai H., Hara R., Herzog H., Yoshimura A., Okamura H., Penninger JM., Slutsky AS., Uhlig S., Kuba K., and Imai Y.
    • Journal Title

      Nat Microbiol.

      Volume: 4(2) Pages: 258-268

    • DOI

      10.1038/s41564-018-0289-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05970, KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-16H05256, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-17K19693, KAKENHI-PROJECT-17H06175
  • [Journal Article] The functional role of endogenous APJ agonists; Apelin and Elabela/Toddler in cardiovascular diseases2019

    • Author(s)
      Sato Teruki、Kuba Keiji
    • Journal Title

      Folia Pharmacol. Jpn.

      Volume: 153 Issue: 4 Pages: 172-178

    • DOI

      10.1254/fpj.153.172

    • NAID

      130007630616

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15879, KAKENHI-PROJECT-17H04028
  • [Journal Article] Apelin inhibition prevents resistance and metastasis associated with anti‐angiogenic therapy2019

    • Author(s)
      Uribesalgo I, Hoffmann D, Zhang Y, Kavirayani A, Lazovic J, Berta J, Novatchkova M, Pai TP, Wimmer RA, Laszlo V, Schramek D, Karim R, Tortola L, Deswal S, Haas L, Zuber J, Szucs M, Kuba K, Dome B, Cao Y, Haubner B, Penninger JM
    • Journal Title

      EMBO Molecular Medicine

      Volume: 11

    • DOI

      10.15252/emmm.201809266

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Journal Article] The CCR4-NOT Deadenylase Complex Maintains Adipocyte Identity2019

    • Author(s)
      Takahashi A., Takaoka S., Kobori S., Yamaguchi T., Ferwati S., Kuba K., Yamamoto T., and Suzuki T.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Pages: 5274-5274

    • DOI

      10.3390/ijms20215274

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07079, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-18K15038
  • [Journal Article] Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling.2019

    • Author(s)
      Sato Teruki、Kadowaki Ayumi、Suzuki Takashi、Ito Hiroshi、Watanabe Hiroyuki、Imai Yumiko、Kuba Keiji
    • Journal Title

      Int J Mol Sci.

      Volume: 20 Pages: 20-20

    • DOI

      10.3390/ijms20020239

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15879, KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-16K09415, KAKENHI-PROJECT-17K19693
  • [Journal Article] New aspects of poly(A) tail shortening of mRNA in controlling heart functions2018

    • Author(s)
      Kuba K.
    • Journal Title

      Folia Pharmacol. Jpn.

      Volume: 151(3) Issue: 3 Pages: 94-99

    • DOI

      10.1254/fpj.151.94

    • NAID

      130006470906

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Journal Article] The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.2018

    • Author(s)
      Yamaguchi Tomokazu et al
    • Journal Title

      Sci. Signal.

      Volume: 11 Issue: 516 Pages: 3638-3638

    • DOI

      10.1126/scisignal.aan3638

    • NAID

      120006707526

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K05265, KAKENHI-PROJECT-17K19693, KAKENHI-PLANNED-15H05978, KAKENHI-PUBLICLY-17H05610, KAKENHI-PUBLICLY-17H06018, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-16H05296, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-15KT0147, KAKENHI-PROJECT-15K18480, KAKENHI-PROJECT-16K19013, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18K15879, KAKENHI-PUBLICLY-17H05607, KAKENHI-PROJECT-16H04745, KAKENHI-PROJECT-16K09415, KAKENHI-PROJECT-17K07292, KAKENHI-PROJECT-16K14652, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-17H01533
  • [Journal Article] Involvement of RSK1 activation in malformin-enhanced cellular fibrinolytic activity.2018

    • Author(s)
      Koizumi Y, Nagai K, Gao L, Koyota S, Yamaguchi T, Natsui M, Imai Y, Hasumi K, Sugiyama T, Kuba K
    • Journal Title

      Sci Rep.

      Volume: 8(1) Pages: 5472-5472

    • DOI

      10.1038/s41598-018-23745-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-17K19693
  • [Journal Article] ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage.2017

    • Author(s)
      Sato T, Sato C, Kadowaki A, Watanabe H, Ho L, Ishida J, Yamaguchi T, Kimura A, Fukamizu A, Penninger JM, Reversade B, Ito H, Imai Y, Kuba K
    • Journal Title

      Cardiovasc Res.

      Volume: 113(7) Pages: 1-10

    • DOI

      10.1093/cvr/cvx061

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253083, KAKENHI-PROJECT-26293050, KAKENHI-PROJECT-15K15304, KAKENHI-PROJECT-15K18965, KAKENHI-PROJECT-16K19013, KAKENHI-PROJECT-17K07131, KAKENHI-PROJECT-17K19693, KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H01519, KAKENHI-PROJECT-16H05296, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-17H06179
  • [Journal Article] Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives.2017

    • Author(s)
      Freyer Laina、Hsu Chih-Wei、Nowotschin Sonja、Pauli Andrea、Ishida Junji、Kuba Keiji、Fukamizu Akiyoshi、Schier Alexander F.、Hoodless Pamela A.、Dickinson Mary E.、Hadjantonakis Anna-Katerina
    • Journal Title

      Cell Rep.

      Volume: 20 Pages: 2116-2130

    • DOI

      10.1016/j.celrep.2017.08.014

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07131, KAKENHI-PROJECT-17H01519, KAKENHI-PROJECT-17H04028
  • [Journal Article] Evaluation of Lecithinized Superoxide Dismutase for the Prevention of Acute Respiratory Distress Syndrome in Animal Models.2017

    • Author(s)
      Tanaka KI, Tamura F, Sugizaki T, Kawahara M, Kuba K, Imai Y, Mizushima T
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 56 Pages: 179-190

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Journal Article] The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription.2017

    • Author(s)
      Rodriguez-Gil Alfonso、Ritter Olesja、Saul Vera V.、Wilhelm Jochen、Yang Chen-Yuan、Grosschedl Rudolf、Imai Yumiko、Kuba Keiji、Kracht Michael、Schmitz M. Lienhard
    • Journal Title

      Sci Rep

      Volume: 7(1) Pages: 3547-3547

    • DOI

      10.1038/s41598-017-03708-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19693, KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-17H06179
  • [Journal Article] Evaluation of Lecithinized Superoxide Dismutase for the Prevention of Acute Respiratory Distress Syndrome in Animal Models.2017

    • Author(s)
      Tanaka KI, Tamura F, Sugizaki T, Kawahara M, Kuba K, Imai Y, Mizushima T
    • Journal Title

      Am J Respir Cell Mol Biol.

      Volume: 56(2) Pages: 179-190

    • DOI

      10.1165/rcmb.2016-0158oc

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05978, KAKENHI-PROJECT-26460177, KAKENHI-PROJECT-15K15304
  • [Journal Article] Vacuolar protein sorting 34 regulates myofibril proteostasis to prevent hypertrophic cardiomyopathy2017

    • Author(s)
      Kimura H, Eguchi S, Sasaki J, Kuba K, Nakanishi H, Takasuga S, Yamazaki M, Goto A, Watanabe H, Itoh H, Imai Y, Suzuki A, Mizushima N, Sasaki T
    • Journal Title

      JCI insight

      Volume: 2(1) Pages: 89462-89478

    • DOI

      10.1172/jci.insight.89462

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05978, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26253083, KAKENHI-PROJECT-15H04693, KAKENHI-PROJECT-26293050, KAKENHI-PROJECT-26460059, KAKENHI-PROJECT-26461458, KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-15K15304, KAKENHI-PLANNED-25111005, KAKENHI-PROJECT-26440020, KAKENHI-PROJECT-26670132, KAKENHI-PROJECT-15K18857, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-17H01400, KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-26640081, KAKENHI-PLANNED-15H05899
  • [Journal Article] Structure-activity relationship of cyclic pentapeptide malformins as fibrinolysis enhancers.2016

    • Author(s)
      Koizumi Y, Nagai K, Hasumi K, Kuba K, Sugiyama T
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 26 Pages: 5267-5271

    • DOI

      10.1016/j.bmcl.2016.09.045

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293050, KAKENHI-PROJECT-26350969, KAKENHI-PROJECT-15K15304
  • [Journal Article] Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis.2016

    • Author(s)
      Yang CY, Ramamoorthy S, Boller S, Rosenbaum M, Rodriguez Gil A, Mittler G, Imai Y, Kuba K, Grosschedl R
    • Journal Title

      Genes Dev

      Volume: 30 Pages: 2310-2324

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15304
  • [Journal Article] Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis.2016

    • Author(s)
      Yang CY, Ramamoorthy S, Boller S, Rosenbaum M, Rodriguez Gil A, Mittler G, Imai Y, Kuba K, Grosschedl R
    • Journal Title

      Genes & Development

      Volume: 30 Pages: 2310-2324

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Journal Article] Cationic nanoparticles directly bind angiotensin-converting enzyme 2 and induce acute lung injury in mice.2015

    • Author(s)
      Sun Y, Kuba K, et al.
    • Journal Title

      Part Fibre Toxicol.

      Volume: 12 Pages: 4-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Journal Article] Cationic nanoparticles directly bind angiotensin-converting enzyme 2 and induce acute lung injury in mice.2015

    • Author(s)
      Sun Y, Kuba K, Jiang C, et al.(23著者、13番目)
    • Journal Title

      Part Fibre Toxicol

      Volume: 12

    • DOI

      10.1186/s12989-015-0080-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Journal Article] Cationic nanoparticles directly bind angiotensin-converting enzyme 2 and induce acute lung injury in mice.2015

    • Author(s)
      Sun Y, Kuba K, et al.
    • Journal Title

      Part Fibre Toxicol.

      Volume: 12 Pages: 4-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15304
  • [Journal Article] The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism.2014

    • Author(s)
      Demetz E, Schroll A, Auer K, Heim C, Patsch JR, Eller P, Theurl M, Lener D, Stanzl U, Seifert M, Haschka D, Asshoff M, Dichtl S, Nairz M, Huber E, Stadlinger M, Li X, Pallweber P, Scharnagl H, Stojakovic T, Marz W, Kleber ME, Garlaschelli K, Uboldi P, Catapano AL, Kuba K, Imai Y, Arita M, Tancevski I.
    • Journal Title

      Cell Metab

      Volume: 20 Pages: 787-798

    • DOI

      10.1016/j.cmet.2014.09.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116006, KAKENHI-PROJECT-26293050
  • [Journal Article] Aglobal in vivo Drosophila RNAi screen identifies NOT3 as aconserved regulator of heart function.2010

    • Author(s)
      Neely G, Kuba K, et al.
    • Journal Title

      Cell

      Volume: 141 Pages: 142-153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390155
  • [Journal Article] 種間で保存された心機能調節因子NOT3の大規模in vivoショウジョウバエRNAiスクリーニングによる同定2010

    • Author(s)
      久場敬司, 他
    • Journal Title

      細胞工学

      Volume: 29 Pages: 592-593

    • Data Source
      KAKENHI-PROJECT-21659198
  • [Journal Article] Inhibition of endostatin/collagen XVIII deteriorates left ventricular remodeling and heart failure in rat myocardial infarction model.2010

    • Author(s)
      Isobe K, Kuba K, Isobe M, et al.
    • Journal Title

      Circ.J 74(1)

      Pages: 109-119

    • NAID

      10025941400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659198
  • [Journal Article] Trilogy of ACE2:Apeptidase in the renin-angiotensin system, a SARS receptor, and a partner for amino acid transporters.2010

    • Author(s)
      Kuba K, et al.
    • Journal Title

      Pharmacol.Ther.

      Volume: 128 Pages: 119-128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390155
  • [Journal Article] 種間で保存された心機能調節因子NOT3の大規模in vivoショウジョウバエRNAiスクリーニングによる同定2010

    • Author(s)
      久場敬司, 他
    • Journal Title

      細胞工学

      Volume: 29 Pages: 592-593

    • Data Source
      KAKENHI-PROJECT-22390155
  • [Journal Article] PI3K gamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway.2010

    • Author(s)
      Haubner BJ, Kuba K, Imai Y, et al.
    • Journal Title

      PLoS One. 5(2)

      Pages: 9350-9357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659198
  • [Journal Article] Trilogy of ACE2 : A peptidase in the renin-angiotensin system, a SARS receptor, and a partner for amino acid transporters.2010

    • Author(s)
      Kuba K, et al.
    • Journal Title

      Pharmacol.Ther.

      Volume: 128 Pages: 119-128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659198
  • [Journal Article] A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.2010

    • Author(s)
      Neely G, Kuba K, et al.
    • Journal Title

      Cell

      Volume: 141 Pages: 142-153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659198
  • [Journal Article] Orphan Transporter SLC6A18 Is Renal Neutral Amino Acid Transporter B0AT32009

    • Author(s)
      Singer D, Kuba K, et al.
    • Journal Title

      J Biol Chem. 284(30)

      Pages: 19953-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659198
  • [Journal Article] Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations2009

    • Author(s)
      Camargo S, Kuba K, et.al.
    • Journal Title

      Gastroenterology 136(3)

      Pages: 872-882

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] The role of ACE2 in pulmonary diseases--relevance for the nephrologist2009

    • Author(s)
      Oudit GY, Kuba K, et.al.
    • Journal Title

      Nephrol Dial Transplant 24(5)

      Pages: 1362-1365

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] Tissue-specificamino acid transporter partners ACE2 and Collectrin differentially interact with Hartnupmutations2008

    • Author(s)
      Camargo SM, Kuba K, et.al.
    • Journal Title

      Gastroenterology

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] Identification ofoxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury2008

    • Author(s)
      Imai Y, Kuba K, et.al.
    • Journal Title

      Cell 133(2)

      Pages: 235-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] The discoveryof ACE2 and its role in acute lung injury2008

    • Author(s)
      Penninger J, Imai Y, Kuba K
    • Journal Title

      ExpPhysiol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] Thediscovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice2008

    • Author(s)
      Imai Y, Kuba K, Penninger JM
    • Journal Title

      ExpPhysiol 93(5)

      Pages: 543-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] Identification of oxidative stress and toll like receptor 4 signaling as a key pathway of acute lung injury2008

    • Author(s)
      Imai Y, Kuba K, et.al.
    • Journal Title

      Cell 18 ; 133(2)

      Pages: 235-249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] ACE2の疾患病態発症における役割2008

    • Author(s)
      久場敬司、今井由美子、木村彰方
    • Journal Title

      医学のあゆみ Vol.226, No.11

    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] Toll様受容体4-TRIFを介した過剰免疫はH5N1インフルエンザウイルスによる呼吸不全を重症化させる2008

    • Author(s)
      今井由美子、久場敬司、Penninger JM.
    • Journal Title

      細胞工学 27(7)

      Pages: 696-97

    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] Lessonsfrom SARS a new potential therapy for acuterespiratory distress syndrome (ARDS) withangiotensin converting enzyme 2 (ACE2)]2008

    • Author(s)
      Imai Y, Kuba K, Penninger JM
    • Journal Title

      Masui 57(3)

      Pages: 302-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] Renin angiotensin system and acute respiratory distress syndrome (ARDS)2007

    • Author(s)
      Imai Y, Kuba K, Penninger JM
    • Journal Title

      Drug Discovery Today 3

      Pages: 225-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload2007

    • Author(s)
      Kuba K, et. al.(30著者、1番目)
    • Journal Title

      Circulation Research 101(4)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] Angiotensin-converting enzyme 2 in acuterespiratory distress syndromeal.2007

    • Author(s)
      Imai Y, Kuba K, Penninger JM
    • Journal Title

      Cell Mol Life Sci 64(15)

      Pages: 2006-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Journal Article] Impaired heartcontractility in Apelin gene-deficient miceassociated with aging and pressure overload2007

    • Author(s)
      Kuba K, Kimura A, et.al.
    • Journal Title

      Circ Res 101(4)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Patent] アンジオテンシン変換酵素2活性を有する原核微生物由来ポリペプチドの医薬用途2020

    • Inventor(s)
      久場敬司
    • Industrial Property Rights Holder
      久場敬司
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] Identification of B38-CAP as an ACE2-like enzyme to suppress hypertension and cardiac dysfunction in mice2020

    • Author(s)
      Keiji Kuba, Takafumi Minato, Satoru Nirasawa, Teruki Sato, Tomokazu Yamaguchi, Hiroyuki Watanabe, Yumiko Imai, Saori Takahashi
    • Organizer
      第93回 日本薬理学会年会(紙上開催)
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages2020

    • Author(s)
      Jianbo An,Taeko Naruse,Kunihiko Hinohara,Yurie Soejima,Motoji Sawabe,Yasuaki Nakagawa,Koichiro Kuwahara,Keiji Kuba,Akinori Kimura
    • Organizer
      第93回 日本薬理学会年会(紙上開催)
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] Dissecting the role of CNOT6L deadenylase in pressure overload-induced cardiac fibrosis2020

    • Author(s)
      山口智和、佐藤輝紀、湊隆文、安健博、星崎みどり、渡邊博之、今井由美子、山本雅、久場敬司
    • Organizer
      第93回 日本薬理学会年会(紙上開催)
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] 後天性赤芽球癆における骨髄性腫瘍関連遺伝子の体細胞変異に関する研究(PRCA-NGS2017)2019

    • Author(s)
      幸丸純貴,小代田宗一,久場敬二,藤島直仁,嵯峨知生,面川 歩,植木重治,石田文宏,中尾眞二,松田 晃,太田晶子,通山 薫,鈴木隆二,三谷絹子,廣川 誠
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08856
  • [Presentation] mRNA poly(A)制御の破綻による循環器疾患の病態発現機構の解明2019

    • Author(s)
      久場 敬司
    • Organizer
      第42回 日本分子生物学会年会 ワークショップ3AW-08「RNA制御と疾患」
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] RNA制御の破綻による循環器疾患の病態発現機構2019

    • Author(s)
      久場 敬司
    • Organizer
      第29回 日本循環薬理学会・第55回高血圧関連疾患モデル学会合同学会 シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] 細胞増殖制御におけるユビキチン転移酵素CNOT4の機能解析2019

    • Author(s)
      山口 智和、久場 敬司
    • Organizer
      第7回 CCR4-NOT研究会
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] RNA制御による循環機能調節の分子機構2019

    • Author(s)
      久場 敬司
    • Organizer
      第22回京都心血管代謝セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] MRTF-Aはマクロファージ機能を制御して動脈硬化形成に関わる2019

    • Author(s)
      安 健博,成瀬 妙子,日野原 邦彦,副島 友莉恵,沢辺 元司,中川 靖章,桑原 宏一郎,久場 敬司,木村 彰方
    • Organizer
      第29回 日本循環薬理学会・第55回高血圧関連疾患モデル学会合同学会
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] CCR4-NOT複合体を介したRNA制御による生体恒常性維持機構2019

    • Author(s)
      久場敬司
    • Organizer
      第3回 理論免疫学ワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] 心臓リモデリングにおける CCR4-NOT deadenylaseの機能解析2019

    • Author(s)
      安健博、佐藤 輝紀、湊 隆文、山口 智和、星崎 みどり、夏井 美幸、 渡邊 博之、今井 由美子、山本 雅、久場 敬司
    • Organizer
      第92回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] 単球/マクロファージ活性化制御における CNOT3の役割・機能の解析2019

    • Author(s)
      安健博、久場 敬司
    • Organizer
      第7回 CCR4-NOT研究会
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] mRNA deadenylation-mediated control of cardiac homeostasis2019

    • Author(s)
      Keiji Kuba
    • Organizer
      The 50th NIPS International Symposium ‘MIRACLES’ in Cardiovascular Physiology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] CCR4-NOT脱アデニル化因子による 心臓リモデリング抑制作用の解析2019

    • Author(s)
      山口 智和、佐藤輝紀、湊隆文、安健博、星崎みどり、渡邊博之、今井由美子、山本雅、久場 敬司
    • Organizer
      第29回 日本循環薬理学会・第55回高血圧関連疾患モデル学会合同学会
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] 肥満組織におけるCNOT4ユビキチン リガーゼの生理機能解析2019

    • Author(s)
      山口 智和、佐藤 輝紀、星崎 みどり、山本 雅、今井 由美子、久場 敬司
    • Organizer
      第92回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] RNA 制御を介した心機能の恒常性維持機構の解明2019

    • Author(s)
      久場 敬司
    • Organizer
      Research PlaNet 2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] CCR4-NOT脱アデニル化酵素複合体による心機能制御機構の解明2018

    • Author(s)
      山口智和, 鈴木享, 佐藤輝紀, 高橋明格, 山本雅, 今井由美子, 久場敬司
    • Organizer
      第20回日本RNA学会年会
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] A bacteria-derived ACE2-like enzyme suppresses cardiac remodeling and dysfunction in mice.2018

    • Author(s)
      湊隆文, 韮澤悟, 佐藤輝紀, 小澤諒, 高橋砂織, 渡邊博之, 久場敬司
    • Organizer
      第2回日本循環器学会基礎研究フォーラム
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] 微生物由来のアンジオテンシン変換酵素2(ACE2)様酵素による心臓リモデリング・機能不全の改善2018

    • Author(s)
      久場敬司, 佐藤輝紀, 湊隆文, 韮澤悟, 小澤諒, 山口智和, 中原和彦, 渡邊博之, 今井由美子,高橋砂織
    • Organizer
      生理学研究所研究会
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] 貧食細胞由来のNPYとそのY1受容体の重症インフルエンザの病態における役割(Phagocytes-derives NPY and Y1 receptor axis controls the pathology of severe influenza virus infection)2018

    • Author(s)
      星崎みどり、藤原誠樹、市田悠、丹下喜恵、黒田悦史、石井健、久場敬司、今井由美子
    • Organizer
      第11回次世代アジュバント研究会
    • Data Source
      KAKENHI-PROJECT-17H06179
  • [Presentation] CCR4-NOT脱アデニル化酵素複合体によるAtg7依存性細胞死の阻害と心機能改善作用2018

    • Author(s)
      山口智和, 鈴木享, 佐藤輝紀, 高橋明格, 門脇歩美, 夏井美幸, 小泉幸央, 山本雅, 今井由美子, 久場敬司
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] 心臓の恒常性維持における分子ネットワークとシステム連関2018

    • Author(s)
      久場敬司
    • Organizer
      第83回 秋田県医学会総会・秋田県医師会設立71周年記念医学大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] 心不全病態における新規APJリガンドELABELAの機能的意義の解明2017

    • Author(s)
      佐藤輝紀、山口智和、渡邊博之、門脇歩美、佐藤チトセ、伊藤宏、今井由美子、 久場敬司
    • Organizer
      第68回薬理学会北部会
    • Data Source
      KAKENHI-PROJECT-16K19013
  • [Presentation] 新規心不全治療標的としてのApelin/ELABELA -APJ受容体システム2017

    • Author(s)
      佐藤輝紀、渡邊博之、伊藤宏、久場敬司
    • Organizer
      第21回日本心不全学会学術集会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K19013
  • [Presentation] 新規APJリガンドELABELAは圧負荷やアンジオテンシンIIによる心臓リモデリングを抑制する2017

    • Author(s)
      佐藤輝紀, 渡邊博之,山口智和,木村彰方, 深水昭吉, Josef PENNINGER, Reversade BRUNO, 伊藤宏, 今井由美子, 久場敬司
    • Organizer
      第21回日本心不全学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K19013
  • [Presentation] 心不全病態におけるRNA分解制御の新しい生理的意義2017

    • Author(s)
      久場敬司
    • Organizer
      日本薬理学会 シンポジウム
    • Place of Presentation
      長崎
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15304
  • [Presentation] RNA deadenylation-guided control of cardiac homeostasis.2017

    • Author(s)
      Kuba K
    • Organizer
      Cutting Edge Developments in RNA Biology for the Control of Gene Expression.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] mRNA deadenylation-guided regulation of cardiac homeostasis2017

    • Author(s)
      久場 敬司
    • Organizer
      理化学研究所IMS疾患生物学セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] New aspects of RNA decay in controlling heart function2017

    • Author(s)
      久場 敬司
    • Organizer
      富山大学 大学院特別セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] 心不全病態におけるRNA分解制御の新しい生理的意義2017

    • Author(s)
      久場敬司
    • Organizer
      第90回日本薬理学会 シンポジウム3
    • Place of Presentation
      長崎
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] 心不全病態におけるRNA分解制御の新しい生理的意義2017

    • Author(s)
      久場 敬司
    • Organizer
      第21回 日本心不全学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04028
  • [Presentation] CCR4-NOT complex controls adenine nucleotide metabolism and energy sensing in cardiac homeostasis2016

    • Author(s)
      久場敬司
    • Organizer
      The 89th JBS meeting symposium 3S17
    • Place of Presentation
      東北大学
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] RNA代謝制御による心機能の恒常性維持2016

    • Author(s)
      久場敬司
    • Organizer
      第10回 京阪神心不全研究会
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] RNA分解による心臓エネルギー代謝の恒常性維持2016

    • Author(s)
      久場敬司
    • Organizer
      第4回 CCR4-NOT研究会
    • Place of Presentation
      秋田
    • Year and Date
      2016-02-12
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] Dissecting the functional role of A Novel APJ ligand, ELABELA, in heart failure2016

    • Author(s)
      佐藤輝紀、久場敬司
    • Organizer
      日本薬理学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15K15304
  • [Presentation] 心臓のmRNA poly(A)分解とエネルギー感知シグナルの相互作用機構の解明2016

    • Author(s)
      山口智和、鈴木享、佐藤輝紀、夏井美幸、門脇歩美、佐藤チトセ、小泉幸央、高橋明格、山本雅、今井由美子、久場敬司
    • Organizer
      第26回 日本循環薬理学会
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] CCR4-NOT complex controls adenine nucleotide metabolism and energy sensing in cardiac homeostasis2016

    • Author(s)
      久場敬司
    • Organizer
      日本生化学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-15K15304
  • [Presentation] 発生期Apelin受容体リガンドElabelaによる心機能調節とRAS系制御2016

    • Author(s)
      久場敬司
    • Organizer
      第2回血管生理学セミナー
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15304
  • [Presentation] Dissecting the functional role of A Novel APJ ligand, ELABELA, in heart failure2016

    • Author(s)
      佐藤輝紀、久場敬司
    • Organizer
      日本薬理学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] 心不全病態における新規APJリガンドELABELAの機能的意義の解明2016

    • Author(s)
      佐藤輝紀, 山口智和, 渡邊博之, 門脇歩美, 佐藤チトセ, 伊藤宏, 今井由美子, 久場敬司
    • Organizer
      第26回 日本循環薬理学会
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] 心不全病態における新規APJリガンドELABELAの機能的意義の解明2016

    • Author(s)
      佐藤輝紀, 山口智和, 渡邊博之, 門脇歩美, 佐藤チトセ, 伊藤宏, 今井由美子, 久場敬司
    • Organizer
      日本循環薬理学会
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-15K15304
  • [Presentation] 心不全病態における新規APJリガンドELABELAの機能的意義の解明2016

    • Author(s)
      佐藤輝紀、山口智和、渡邊博之、門脇歩美、佐藤チトセ、伊藤宏、今井由美子、 久場敬司
    • Organizer
      循環薬理学会
    • Place of Presentation
      信州大学医学部附属病院 大会議室
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-16K19013
  • [Presentation] Signaling network to maintain cardiac homeostasis in failing hearts2015

    • Author(s)
      久場敬司
    • Organizer
      The 4th Hsien Wu and Ray Wu Symposia “Proteins, Genes and Diseases”
    • Place of Presentation
      北京
    • Year and Date
      2015-08-10
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] Signaling network to maintain cardiac homeostasis in failing hearts2015

    • Author(s)
      久場敬司
    • Organizer
      The 4th Hsien Wu and Ray Wu Symposia “Proteins, Genes and Diseases”
    • Place of Presentation
      北京
    • Year and Date
      2015-08-10
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15304
  • [Presentation] 心臓における新規Apelin受容体リガンドApelaの機能的意義の解析2015

    • Author(s)
      久場敬司
    • Organizer
      生理学研究所 研究会 2015 「心臓・血管系の包括的な機能統合研究」
    • Place of Presentation
      岡崎
    • Year and Date
      2015-10-29
    • Data Source
      KAKENHI-PROJECT-15K15304
  • [Presentation] 心臓における新規Apelin受容体リガンドApelaの機能的意義の解析2015

    • Author(s)
      久場敬司
    • Organizer
      生理学研究所 研究会 2015 「心臓・血管系の包括的な機能統合研究」
    • Place of Presentation
      岡崎
    • Year and Date
      2015-10-29
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] Angiotensin converting enzyme 2 (ACE2) links Apelin and angiotensin systems in controlling heart function.2015

    • Author(s)
      久場敬司
    • Organizer
      日本解剖学会・日本生理学会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] 心臓のmRNA分解とエネルギー代謝の恒常性維持2015

    • Author(s)
      久場敬司
    • Organizer
      第2回 仙台先進循環器研究会
    • Place of Presentation
      仙台
    • Year and Date
      2015-06-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] CCR4-NOT複合体によるアデニン核酸制御機構の解析2015

    • Author(s)
      山口智和、久場敬司
    • Organizer
      RNA学会
    • Place of Presentation
      札幌
    • Year and Date
      2015-07-13
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] アンジオテンシン変換酵素2(ACE2)の多彩な生理機能と制御機構の解明2015

    • Author(s)
      久場敬司
    • Organizer
      第160回日本循環器学会東北地方会
    • Place of Presentation
      盛岡
    • Year and Date
      2015-04-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] CNOT3を介した心臓のアデニン核酸制御機構の解析2015

    • Author(s)
      山口智和、久場敬司
    • Organizer
      第66回 日本薬理学会北部会
    • Place of Presentation
      富山
    • Year and Date
      2015-09-18
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] RNA分解制御による心臓エネルギー恒常性維持の分子機構2015

    • Author(s)
      久場敬司
    • Organizer
      BMB2015
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-04
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] mRNA分解制御を介した心臓の恒常性維持2015

    • Author(s)
      久場敬司
    • Organizer
      第一回 J-ISCP学術集会
    • Place of Presentation
      京都
    • Year and Date
      2015-06-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] Dissecting the mechanisms for regulation of cardiac energy metabolism by CCR4-NOT complex2014

    • Author(s)
      久場敬司
    • Organizer
      第 16 回 日本RNA学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-07-23
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] CCR4-NOT deadenylase complex links mRNA metabolism to energy sensing in cardiac homeostasis2014

    • Author(s)
      久場敬司
    • Organizer
      第 31 回 国際心臓研究学会(ISHR)日本部会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-11-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] 酵母からヒトまで保存されたCCR4-NOT複合体による心機能制御メカニズム2014

    • Author(s)
      久場敬司
    • Organizer
      第24回 日本循環薬理学会
    • Place of Presentation
      山形
    • Year and Date
      2014-12-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] Genome-wideショウジョウバエスクリーニングによる新規の心機能調節遺伝子の単離2010

    • Author(s)
      久場敬司
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪市
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-21659198
  • [Presentation] ゲノムワイドRNAiスクリーニングによる心機能調節因子NOT3の同定2010

    • Author(s)
      久場敬司
    • Organizer
      第20回日本循環薬理学会
    • Place of Presentation
      札幌市
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-21659198
  • [Presentation] CNOT3はショウジョウバエからマウス、ヒトまで保存された新規の心機能調節因子である。2010

    • Author(s)
      久場敬司
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22390155
  • [Presentation] ゲノムワイドRNAiスクリーニングによる心機能調節因子NOT3の同定2010

    • Author(s)
      久場敬司
    • Organizer
      第20回 日本循環薬理学会
    • Place of Presentation
      札幌市
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-22390155
  • [Presentation] CNOT3はショウジョウバエからマウス、ヒトまで保存された新規の心機能調節因子である2010

    • Author(s)
      久場敬司
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21659198
  • [Presentation] アンジオテンシン変換酵素2(ACE2)-apelinによる循環機能調節2009

    • Author(s)
      久場敬司
    • Organizer
      生理研研究会
    • Place of Presentation
      愛知県、岡崎市
    • Year and Date
      2009-11-25
    • Data Source
      KAKENHI-PROJECT-21659198
  • [Presentation] アンジオテンシン変換酵素(ACE2)と心血管機能制御2008

    • Author(s)
      久場敬司
    • Organizer
      第12回Molecular Cardiocvascular conference
    • Place of Presentation
      北海道、キロロ
    • Year and Date
      2008-09-05
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] 疾患病態発症におけるACE2(アンジオテンシン変換酵素2)の役割2008

    • Author(s)
      久場敬司
    • Organizer
      第4回宮崎サイエンスキャンプ
    • Place of Presentation
      ワールドコンベンションセンターサミット・宮崎
    • Year and Date
      2008-02-15
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] アンジオテンシン変換酵素2(ACE2)によるARDS/急性肺傷害阻止のメカニズム2008

    • Author(s)
      久場敬司
    • Organizer
      第9回東京アンジオテンシン研究会
    • Place of Presentation
      東京(経団連会館)
    • Year and Date
      2008-12-13
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] 11th Cardiovascular Genomicsand Atherosclerosis Symposium2008

    • Author(s)
      久場敬司
    • Organizer
      Angiotensin converting enzyme 2 and itsnew substrate Apelin in heart diseases
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-11-01
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] Angiotensin converting enzyme 2 and itsnew substrate, Apelin2008

    • Author(s)
      久場敬司
    • Organizer
      MTT International Symposium
    • Place of Presentation
      東京医科歯科大学、難治疾患研究所1階会議室
    • Year and Date
      2008-03-07
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] アンジオテンシン変換酵素2(ACE2)の疾患病態発症における役割2008

    • Author(s)
      久場敬司
    • Organizer
      第6回宮崎生活習慣病研究会
    • Place of Presentation
      宮崎観光ホテル、3階「緋耀の間」
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] 急性肺傷害の炎症におけるSARSレセプターACE2の役割2008

    • Author(s)
      久場敬司
    • Organizer
      メタボリックリサーチフォーラム
    • Place of Presentation
      東京
    • Year and Date
      2008-03-15
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] アンジオテンシン変換酵素(ACE2)と心血管機能制御2008

    • Author(s)
      久場敬司
    • Organizer
      第12回MolecularCardiocvascular conference
    • Place of Presentation
      北海道キロロ、ホテルピアノ2階「キロロボールルーム・大」
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] 夏の研修旅行 : 研究三都物語、大阪、トロント、ウィーン2008

    • Author(s)
      久場敬司
    • Organizer
      深水昭吉研究室
    • Place of Presentation
      和光純薬湯河原研修所、大会議室
    • Year and Date
      2008-07-27
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] 新規生理活性物質アペリン遺伝子欠損マウスの心筋梗塞モデルにおける心機能障害の研究2008

    • Author(s)
      久場敬司
    • Organizer
      第13回アディポサイエンス研究会シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2008-08-22
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] A critical role of Angiotensin converting enzyme 2 (ACE2) in severe acute lung injury2007

    • Author(s)
      Kuba K, Imai Y, Uhlig S, Slutsky A, Penninger JM
    • Organizer
      American Thoracic Society International Conference
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] 心機能維持におけるACE2の役割2007

    • Author(s)
      久場敬司
    • Organizer
      第8回アンジオテンシン研究会
    • Place of Presentation
      東京、経団連会館ビル
    • Year and Date
      2007-12-08
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] Apelin playsa crucial role in maintaining heartcontractility in aging and pressureoverload2007

    • Author(s)
      久場敬司
    • Organizer
      第11回MolecularCardiocvascular Conference
    • Place of Presentation
      北海道キロロ
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] Endogenous Apelin maintains heart contractility in aging and pressure overload2007

    • Author(s)
      Kuba K, et. al.
    • Organizer
      American Heart Association Scientific Session
    • Place of Presentation
      Orlando, USA
    • Year and Date
      2007-11-07
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] A critical role of Angiotensinconverting enzyme 2(ACE2)in severe acutelung injury2007

    • Author(s)
      久場敬司
    • Organizer
      ATS International Conference2007
    • Place of Presentation
      米国サンフランシスコ
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] SARSレセプターACE2によるARDS治療2007

    • Author(s)
      久場敬司
    • Organizer
      第38回血管研究会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] Endogenous Apelin maintains heartcontractility in aging and pressureoverload2007

    • Author(s)
      久場敬司
    • Organizer
      AHA Scientific Session 2007
    • Place of Presentation
      米国オーランド
    • Data Source
      KAKENHI-PROJECT-19890062
  • [Presentation] Dissecting the role of CCR4-NOT-associated ubiquitin converting enzyme in controlling heart functions.

    • Author(s)
      山口智和、門脇歩美、小泉幸央、夏井美幸、佐藤チトセ、今井由美子、久場敬司
    • Organizer
      第88回 日本薬理学会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-26293050
  • [Presentation] A crucial role of CNOT3 in stem cell proliferation and early embryonic development

    • Author(s)
      小泉幸央、山口智和、門脇歩美、夏井美幸、佐藤チトセ、今井由美子、久場敬司
    • Organizer
      第88回 日本薬理学会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-26293050
  • 1.  KIMURA Akinori (60161551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 2.  SATO Teruki (30733422)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 3.  今井 由美子 (50231163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 4.  本山 悟 (60292372)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  廣川 誠 (50241667)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  小松 久美 (70646554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  石田 文宏 (80311695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  NAKANISHI Hiroki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  EGUCHI Satoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  KOIZUMI Yukio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  NAGAI Kenichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  YAMAGUCHI Yoshifumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  ARAKAWA Satoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  TAKAHASHI Hiroki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  ADACHI shungo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  山口 智和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 17.  石田 純治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 18.  深水 昭吉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 19.  黒田 悦史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  吉村 昭彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  川原 正博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  鈴木 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  後藤 裕樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  佐々木 純子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  高須賀 俊輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  木村 洋貴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  佐々木 雄彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  水島 昇
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  鈴木 亨
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 30.  高橋 明格
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  深尾 亜喜良
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  鈴木 穣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  藤原 俊伸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  伊藤 宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 35.  渡邊 博之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 36.  有田 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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