HONDA MASAHIKO 本多賢彦

… Alternative Names

Honda Masahiko 本多賢彦

HONDA Takehiko 本多賢彦

HONDA Masahiko 本多賢彦

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Researcher Number	10455545
Other IDs	https://orcid.org/0000-0002-4392-6837
Affiliation (Current)	2025: 明治大学, 研究・知財戦略機構(生田), 研究推進員(客員研究員)
Affiliation (based on the past Project Information) *help	2019 – 2023: 近畿大学, 医学部, 助教 2015 – 2017: 国立研究開発法人国立循環器病研究センター, 研究所, 研究員 2014: 国立循環器病研究センター, 研究所, 室員 2011: 独立行政法人国立循環器病研究センター, 分子生物学部, 室員
Review Section/Research Field	Principal Investigator Basic Section 59020:Sports sciences-related / Sports science Except Principal Investigator Pediatrics
Keywords	Principal Investigator 骨格筋 / ノックアウトマウス / トランスジェニックマウス / 好気的代謝 / 遅筋 / 転写コファクター / 持久力 / 過剰発現マウス / 筋代謝 / 生活習慣病 … More / Vgll2 / 筋線維タイプ / 代償性負荷 / 運動 / 運動刺激 / 遅筋化 … More Except Principal Investigator 発生医学 / ポリコーム遺伝子 / 心臓形態形成 / 心不全 / 心臓発生 / ポリコーム遺伝子群 / 形態形成 Less

運動によって活性化する遅筋化促進因子を介した骨格筋特有の好気的代謝制御機構の解明Principal Investigator
- Principal Investigator
  
  本多賢彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Kindai University
Generation and phenotyping of mice overexpressing slow contractile phenotype promoting factor for the development of new metabolic syndrome drugsPrincipal Investigator
- Principal Investigator
  
  Honda Masahiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Kindai University
the basic analysis of molecular mecahnisms of novel fast-to-slow fiber type swiching involeved in transcriptional cofactor Vgll2.Principal Investigator
- Principal Investigator
  
  Honda Masahiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Sports science
- Research Institution
  National Cardiovascular Center Research Institute
Functional analysis of Polycomb-group genes in regulating mechanisms for self-reneual and differentiation of cardiac progenitor cells.
- Principal Investigator
  
  SHIRAI Manabu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Cardiovascular Center Research Institute
Functional analysis of Polycomb-group gene, Pcgf5 in cardiac morphogenesis
- Principal Investigator
  
  SHIRAI Manabu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Cardiovascular Center Research Institute

All 2024 2023 2022 2021 2020 2019 2017 2016 2015

All Journal Article Presentation

[Journal Article] Deoxycytidine Kinase Inactivation Enhances Gemcitabine Resistance and Sensitizes Mitochondrial Metabolism Interference in Pancreatic Cancer2024
- Author(s)
  Dash S, Ueda T, Komuro A, Honda M, Sugisawa R, Okada H.
- Journal Title
  
  Cell Death & Disease
  
  Volume: 131 Issue: 2 Pages: 1-13
- DOI
  10.1038/s41419-024-06531-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06829, KAKENHI-PROJECT-22K11513, KAKENHI-PROJECT-21K07135
[Journal Article] MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance2023
- Author(s)
  Dash Suman, Ueda Takeshi, Komuro Akiyoshi, Amano Hisayuki, Honda Masahiko, Kawazu Masahito, Okada Hitoshi.
- Journal Title
  
  Molecular Cancer Research
  
  Volume: online publication Issue: 5 Pages: 444-457
- DOI
  10.1158/1541-7786.mcr-22-0554
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06829, KAKENHI-PROJECT-22K11513, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-20K07346, KAKENHI-PROJECT-21K07135
[Journal Article] Biallelic truncating variants in<i>VGLL2</i>cause syngnathia in humans2023
- Author(s)
  Agostini Valeria、Tessier Aude、Djaziri Nabila、Khonsari Roman Hossein、Galliani Eva、Kurihara Yukiko、Honda Masahiko、Kurihara Hiroki、Hidaka Kyoko、Tuncbilek Gokhan、Picard Arnaud、Konas Ersoy、Amiel Jeanne、Gordon Christopher T
- Journal Title
  
  Journal of Medical Genetics
  
  Volume: 60 Issue: 11 Pages: 1084-1091
- DOI
  10.1136/jmg-2022-109059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11513
[Journal Article] The Functional Role of Long Non-Coding RNA in Myogenesis and Skeletal Muscle Atrophy2022
- Author(s)
  Hitachi Keisuke、Honda Masahiko、Tsuchida Kunihiro
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 15 Pages: 2291-2291
- DOI
  10.3390/cells11152291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11513, KAKENHI-PROJECT-19H03427, KAKENHI-PROJECT-20K07315
[Journal Article] KDM4B promotes acute myeloid leukemia associated with AML1‐ETO by regulating chromatin accessibility2021
- Author(s)
  Ueda Takeshi、Kanai Akinori、Komuro Akiyoshi、Amano Hisayuki、Ota Kazushige、Honda Masahiko、Kawazu Masahito、Okada Hitoshi
- Journal Title
  
  FASEB BioAdvances
  
  Volume: 3 Issue: 12 Pages: 1020-1033
- DOI
  10.1096/fba.2021-00030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11486, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-20K07346, KAKENHI-PROJECT-21K06829, KAKENHI-PROJECT-21K07135, KAKENHI-PROJECT-21K12239
[Journal Article] Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin2020
- Author(s)
  Oka Naohiro、Komuro Akiyoshi、Amano Hisayuki、Dash Suman、Honda Masahiko、Ota Kazushige、Nishimura Shunji、Ueda Takeshi、Akagi Masao、Okada Hitoshi
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 8 Issue: 4
- DOI
  10.1002/prp2.632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11486, KAKENHI-PROJECT-20K07346, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-18K06941, KAKENHI-PROJECT-18K07211
[Journal Article] Expression Levels of Long Non-Coding RNAs Change in Models of Altered Muscle Activity and Muscle Mass2020
- Author(s)
  Hitachi Keisuke、Nakatani Masashi、Funasaki Shiori、Hijikata Ikumi、Maekawa Mizuki、Honda Masahiko、Tsuchida Kunihiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 5 Pages: 1628-1628
- DOI
  10.3390/ijms21051628
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11486, KAKENHI-PROJECT-19H03427, KAKENHI-PROJECT-17K01485, KAKENHI-PROJECT-17K08646, KAKENHI-PROJECT-20K11247
[Journal Article] Deficiency of Vgll2 Gene Alters the Gene Expression Profiling of Skeletal Muscle Subjected to Mechanical Overload2019
- Author(s)
  Hitachi Keisuke、Inagaki Hidehito、Kurahashi Hiroki、Okada Hitoshi、Tsuchida Kunihiro、Honda Masahiko
- Journal Title
  
  Frontiers in Sports and Active Living
  
  Volume: 1 Pages: 1-4
- DOI
  10.3389/fspor.2019.00041
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07211, KAKENHI-PROJECT-19K11486, KAKENHI-PROJECT-19H03427, KAKENHI-PROJECT-17K08646
[Journal Article] Vestigial-like 2 contributes to normal muscle fiber type distribution in mice2017
- Author(s)
  Honda Masahiko、Hidaka Kyoko、Fukada So-ichiro、Sugawa Ryo、Shirai Manabu、Ikawa Masahito、Morisaki Takayuki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 734-740
- DOI
  10.1038/s41598-017-07149-0
- NAID
  120006957431
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09486, KAKENHI-PROJECT-15K16501
[Presentation] 遅筋化促進因子Vgll2が筋代謝へ及ぼす影響の解析2023
- Author(s)
  本多賢彦、Suman Dash、杉澤良一、古室暁義、上田健、岡田斉
- Organizer
  第9回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-22K11513
[Presentation] 骨格筋の好気的代謝調節における遅筋化促進因子Vgll2の機能解析2023
- Author(s)
  本多賢彦、Suman Dash、古室暁義、上田健、岡田斉
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K11513
[Presentation] 遺伝子改変マウスを用いたVgll2発現量が及ぼす筋代謝への影響の解析2022
- Author(s)
  本多賢彦、Suman Dash、古室暁義、上田健、岡田斉
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K11513
[Presentation] The role for transcriptional cofactor vestigial like family member 2 in functional muscle remodeling induced by chronic overload2019
- Author(s)
  本多賢彦、土持裕胤、常陸圭介、岡田斉
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-19K11486
[Presentation] 慢性的な筋使用に伴う遅筋化における転写コファクターVgll2の機能解析2019
- Author(s)
  本多賢彦、土持裕胤、常陸圭介、岡田斉
- Organizer
  日本筋学会
- Data Source
  KAKENHI-PROJECT-19K11486
[Presentation] 機械的負荷に伴う遅筋化における転写コファクターVgll2の機能解析2019
- Author(s)
  本多賢彦、土持裕胤、常陸圭介、岡田斉
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K11486
[Presentation] Utx欠損は高脂肪食により誘導される肥満を雌マウス特異的に抑制する2019
- Author(s)
  太田一成、古室暁義、天野恭志、本多賢彦、金井昭教、Kai Ge、上田健、岡田斉
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K11486
[Presentation] 慢性的な機械的過負荷に対する骨格筋の適応におけるVgll2の機能解析2017
- Author(s)
  本多賢彦、日高京子、土持裕胤、森崎隆幸
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K16501
[Presentation] Functional analysis of Vgll2 in chronic overload-induced skeletal muscle remodeling2016
- Author(s)
  Masahiko Honda, Kyoko Hidaka, Hirotsugu Tsuchimochi, Takayuki Morisaki
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K16501
[Presentation] マウスの遅筋表現型制御におけるVgll2の機能解析2016
- Author(s)
  本多賢彦、日高京子、深田宗一朗、森崎隆幸
- Organizer
  第二回日本筋学会学術集会
- Place of Presentation
  東京都小平市
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-15K16501
[Presentation] Functional analysis of Vgll2 in muscle plasticity2016
- Author(s)
  Masahiko Honda
- Organizer
  第四回骨格筋若手の会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2016-11-14
- Data Source
  KAKENHI-PROJECT-15K16501
[Presentation] Impact of Vgll2 deficiency on fetal myogenesis2015
- Author(s)
  Honda, M., Hidaka, K., Sugawa, R., Fukada, S., Sumie, N., and Morisaki, T.
- Organizer
  第38回分子生物学会年会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K16501

1. MORISAKI Takayuki (30174410)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. MORISAKI Hiroko (40311451)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. SHIRAI Manabu (70294121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 古室暁義

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 岡田斉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HONDA MASAHIKO 本多 賢彦

Honda Masahiko 本多 賢彦

HONDA Takehiko 本多 賢彦

HONDA Masahiko 本多 賢彦

Research Projects

Research Products

Co-Researchers

運動によって活性化する遅筋化促進因子を介した骨格筋特有の好気的代謝制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation and phenotyping of mice overexpressing slow contractile phenotype promoting factor for the development of new metabolic syndrome drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

the basic analysis of molecular mecahnisms of novel fast-to-slow fiber type swiching involeved in transcriptional cofactor Vgll2.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of Polycomb-group genes in regulating mechanisms for self-reneual and differentiation of cardiac progenitor cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of Polycomb-group gene, Pcgf5 in cardiac morphogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Deoxycytidine Kinase Inactivation Enhances Gemcitabine Resistance and Sensitizes Mitochondrial Metabolism Interference in Pancreatic Cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biallelic truncating variants in<i>VGLL2</i>cause syngnathia in humans2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Functional Role of Long Non-Coding RNA in Myogenesis and Skeletal Muscle Atrophy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KDM4B promotes acute myeloid leukemia associated with AML1‐ETO by regulating chromatin accessibility2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression Levels of Long Non-Coding RNAs Change in Models of Altered Muscle Activity and Muscle Mass2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deficiency of Vgll2 Gene Alters the Gene Expression Profiling of Skeletal Muscle Subjected to Mechanical Overload2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vestigial-like 2 contributes to normal muscle fiber type distribution in mice2017

Author(s)

Journal Title

HONDA MASAHIKO 本多賢彦

Honda Masahiko 本多賢彦

HONDA Takehiko 本多賢彦

HONDA Masahiko 本多賢彦