Shinohara Hiroshi 篠原広志

Researcher Number	10455793
Other IDs
Affiliation (Current)	2025: 東京医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2023: 東京医科大学, 医学部, 講師 2013 – 2018: 東京医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 48010:Anatomy-related / General anatomy (including histology/embryology) Except Principal Investigator Nerve anatomy/Neuropathology / Basic Section 59040:Nutrition science and health science-related / Basic Section 46020:Anatomy and histopathology of nervous system-related
Keywords	Principal Investigator 子宮内電気穿孔法 / 顆粒細胞 / 海馬歯状回 / ニューロン新生 / 神経幹細胞 / ライムラプス観察 / 海馬歯状回顆粒細胞 / 成体期海馬神経幹細胞 / in utero electroporation / 電気穿孔法 / 顆粒細胞層 / 歯状回 / 海馬 … More Except Principal Investigator … More 顆粒細胞 / 海馬 / 歯状回 / ニューロン新生 / 移動 / 成体脳ニューロン新生 / 神経幹細胞 / 脳萎縮 / 老化 / 脳委縮 / 神経変性疾患 / 抗老化 / クレアチン / シクロクレアチン / クレアチン誘導体 / サイクロクレアチン / mouse / Cyclocreatine / DCX / PSA-NCAM / 未熟ニューロンマーカー / 新生ニューロン / 可塑性 / 未熟ニューロン / マーモセット / ヒト / 微小環境 / 細胞内局在 / 分化 / エンドサイトーシス / CXCL12 / 発生 / 細胞移動 / 細胞分化 / CXCR4 / 神経前駆細胞 / 胎生期 / BLBP / GFAP / シグナル分子 / ニューロン分化 Less

起源の異なる海馬神経幹細胞がもたらす成体期神経新生および歯状回形成機構の比較解析Principal Investigator
- Principal Investigator
  
  篠原広志
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Tokyo Medical University
Reexamination of adult neurogenesis in the marmoset and human hippocampus
- Principal Investigator
  
  Seki Tatsunori
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46020:Anatomy and histopathology of nervous system-related
- Research Institution
  Juntendo University
  Tokyo Medical University
A New Approach for Anti-Aging/Neurodegenerative Disease Therapy via Inhibition of Brain Atrophy: Using Creatine Derivatives
- Principal Investigator
  
  Kurosawa Yuko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Medical University
Analysis of embryonic to adult neurogenesis with a special emphasis on microenvironmental signal
- Principal Investigator
  
  Seki Tatsunori
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tokyo Medical University
Search for the origin of adult neural stem cell and analysis of granule cell layer formation in the dentate gyrusPrincipal Investigator
- Principal Investigator
  
  Shinohara Hiroshi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Tokyo Medical University
Analysis of embryonic-to-adult transition in neural progenitors of the hippocampal granule cells
- Principal Investigator
  
  Seki Tatsunori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tokyo Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] PSmad3+/Olig2? expression defines a subpopulation of gfap-GFP+/Sox9+ neural progenitors and radial glia-like cells in mouse dentate gyrus through embryonic and postnatal development2023
- Author(s)
  Ohyama Kyoji、Shinohara Hiroshi M.、Omura Shoichiro、Kawachi Tomomi、Sato Toru、Toda Keiko
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 17 Pages: 1-14
- DOI
  10.3389/fnins.2023.1204012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07233, KAKENHI-PROJECT-23K05995
[Journal Article] The polarity and properties of radial glia-like neural stem cells are altered by seizures with status epilepticus: Study using an improved mouse pilocarpine model of epilepsy2020
- Author(s)
  Sasaki-Takahashi N, Shinohara H, Shioda S, Seki T.
- Journal Title
  
  Hippocampus
  
  Volume: 30 Issue: 3 Pages: 250-262
- DOI
  10.1002/hipo.23153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06930, KAKENHI-PROJECT-16H02684, KAKENHI-PROJECT-20K20392, KAKENHI-PROJECT-16K18983, KAKENHI-PROJECT-20K07233
[Journal Article] Non-radial tortuous migration with cell polarity alterations of newly generated granule neurons in the neonatal rat dentate gyrus2019
- Author(s)
  Namba T, Shinohara H, Seki T
- Journal Title
  
  Brain Struct Funct
  
  Volume: 224 Issue: 9 Pages: 3247-3262
- DOI
  10.1007/s00429-019-01971-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06930, KAKENHI-PROJECT-16K07033, KAKENHI-PROJECT-16K18983
[Journal Article] 1次繊毛形成の正常化はダウン症候群の治療標的に成り得るか？2019
- Author(s)
  篠原　広志
- Journal Title
  
  ファルマシア
  
  Volume: 55 Pages: 703-703
- NAID
  130007671673
- Data Source
  KAKENHI-PROJECT-16K18983
[Journal Article] The role of Pax6 in brain development and its impact on pathogenesis of autism spectrum disorder2018
- Author(s)
  Kikkawa Takako、Casingal Cristine R.、Chun Seung Hee、Shinohara Hiroshi、Hiraoka Kotaro、Osumi Noriko
- Journal Title
  
  Brain Research
  
  Volume: - Pages: 30111-2
- DOI
  10.1016/j.brainres.2018.02.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19372, KAKENHI-PROJECT-16K18983, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-15K08127, KAKENHI-PROJECT-16K20902, KAKENHI-PROJECT-18K14999
[Journal Article] Dynamics and function of CXCR4 in formation of the granule cell layer during hippocampal development2017
- Author(s)
  Miura-Yamamoto Y, Shinohara H, Kashiwagi T, Sato T, Shioda S, Seki T
- Journal Title
  
  Scientific Reports
  
  Volume: 7: 5647 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41598-017-05738-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07033, KAKENHI-PROJECT-16K10000, KAKENHI-PROJECT-16K18983, KAKENHI-PROJECT-16H02684, KAKENHI-PROJECT-15K18962
[Presentation] Temporally regulated expression patterns of Zeb1, Scratch2, and Nkx6-2 in the granule neuronal progenitors of developing mouse dentate gyrus2024
- Author(s)
  高山夏海, 篠原広志, 高橋宗春, 大山恭司
- Organizer
  第17回神経発生討論会＆第20回成体脳のニューロン新生懇談会合同大会
- Data Source
  KAKENHI-PROJECT-20K07233
[Presentation] Development of Olig2+/Sox9+ astrocytes in mouse dentate gyrus2024
- Author(s)
  Shoichiro Omura, Rina Ogawa, Tomomi Kawachi, Aya Ogawa, Yuuki Arai, Hiroki Sugimoto, Hiroshi M Shinohara, Tokiharu Takahashi, Hideyuki Maeda, Kyoji Ohyama
- Organizer
  第17回神経発生討論会＆第20回成体脳のニューロン新生懇談会
- Data Source
  KAKENHI-PROJECT-20K07233
[Presentation] 移動経路や性質が異なる神経前駆細胞によって海馬歯状回は形成される2023
- Author(s)
  篠原広志、石龍徳、髙橋宗春
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07233
[Presentation] 海馬歯状回は様式や性質が異なる神経前駆細胞により形成される2023
- Author(s)
  篠原広志
- Organizer
  第191回東京医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-20K07233
[Presentation] マウス海馬歯状回Olig2 発現アストロサイトの同定2023
- Author(s)
  大村捷一郎, 小川莉奈, 杉本大貴, 嘉和知朋美, 篠原広志, 小川文寧, 新井優樹, 高橋宗春, 前田秀将, 大山恭司
- Organizer
  第29回海馬と高次脳機能学会
- Data Source
  KAKENHI-PROJECT-20K07233
[Presentation] 海馬歯状回は様式や性質が異なる神経前駆細胞により形成される2023
- Author(s)
  篠原広志、石龍徳、高橋宗春
- Organizer
  第128回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-19K06930
[Presentation] 海馬歯状回は様式や性質が異なる神経前駆細胞により形成される2023
- Author(s)
  篠原広志、石龍徳、高橋宗春
- Organizer
  第128回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-20K07233
[Presentation] ニワトリ視床下部発生パターニングの時空間制御2023
- Author(s)
  大山恭司, 小川文寧, 新井優樹, 小川莉奈, 大村捷一郎, Don Won Thomas Kim, 篠原広志, 高橋宗春
- Organizer
  2023年度先進ゲノム拡大班会議
- Data Source
  KAKENHI-PROJECT-20K07233
[Presentation] 海馬歯状回顆粒細胞は異なる経路を移動する前駆細胞によって形成される2022
- Author(s)
  篠原広志、石龍徳、高橋宗春
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-20K07233
[Presentation] 海馬歯状回顆粒細胞は２つの異なる経路を移動する前駆細胞によって形成される2021
- Author(s)
  篠原広志, 石龍徳
- Organizer
  第126回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-19K06930
[Presentation] 背側および腹側の異なる経路によって海馬歯状回顆粒細胞層は形成される2020
- Author(s)
  篠原広志, 石龍徳
- Organizer
  第43回日本神経科学学会
- Data Source
  KAKENHI-PROJECT-19K06930
[Presentation] 起源の異なる海馬神経幹細胞がもたらす成体期神経新生および歯状回形成機構の比較解析2020
- Author(s)
  篠原広志、石龍徳
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07233
[Presentation] 顆粒細胞形成におけるTbr2の機能および顆粒細胞サブタイプ解析2020
- Author(s)
  篠原広志, 石龍徳
- Organizer
  第16回成体脳ニューロン新生懇談会・「個性」創発脳共催研究会in仙台2020
- Data Source
  KAKENHI-PROJECT-16K18983
[Presentation] Tbr2依存/非依存性ニューロン解析から紐解く時空間的な海馬の形成メカニズム2020
- Author(s)
  篠原広志, 石龍徳
- Organizer
  第125回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-16K18983
[Presentation] 海馬歯状回顆粒細胞は２つの異なる経路を移動する前駆細胞によって形成される2020
- Author(s)
  篠原広志、石龍徳
- Organizer
  第126回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-20K07233
[Presentation] 胎生期海馬における神経幹・前駆細胞形成および神経新生機構2019
- Author(s)
  柏木太一,塩田清二,篠原広志,石龍徳
- Organizer
  第124回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] Analysis of cellular migration in developmental dentate gyrus2019
- Author(s)
  Shinohara H, Seki T
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K06930
[Presentation] Two distinctive dorsal and ventral pathways form dentate granule cell layer2019
- Author(s)
  篠原広志、石龍徳
- Organizer
  第124回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] 成体期海馬神経幹細胞の起源探索および海馬歯状回顆粒細胞層形成メカニズムの解析2019
- Author(s)
  篠原広志, 石龍徳
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K18983
[Presentation] Analysis of cellular migration in developmental dentate gyrus2019
- Author(s)
  Shinohara H, Seki T
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] 海馬歯状回顆粒細胞形成の分子メカニズム解析2018
- Author(s)
  篠原広志, 石龍徳
- Organizer
  第123回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] BMPシグナルによる海馬神経細胞形成制御2018
- Author(s)
  柏木太一, 篠原広志, 塩田清二, 石龍徳
- Organizer
  第123回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] Gfap-GFPマウスを用いた発生過程における海馬歯状回形成細胞の移動解析2018
- Author(s)
  篠原　広志、石　龍徳
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K18983
[Presentation] 海馬顆粒細胞層形成過程におけるCXCR4の動態と機能2018
- Author(s)
  山本夕香, 篠原広志,柏木太一,佐藤亨, 塩田清二,石龍徳
- Organizer
  第123回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] Two distinctive dorsal and ventral pathways form dentate granule cell layer2018
- Author(s)
  篠原　広志、石　龍徳
- Organizer
  第124回日本解剖学会
- Data Source
  KAKENHI-PROJECT-16K18983
[Presentation] 海馬歯状回顆粒細胞形成の分子メカニズム解析2018
- Author(s)
  篠原広志、石龍徳
- Organizer
  第123回日本解剖学会総会・全国学術集会（武蔵境）
- Data Source
  KAKENHI-PROJECT-16K18983
[Presentation] Analysis of cellular migration in developmental dentate gyrus2018
- Author(s)
  Shinohara H, Seki T
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] 子宮内電気穿孔法による海馬歯状回メカニズムの解析2017
- Author(s)
  篠原広志、　石龍徳
- Organizer
  第39回神経組織培養研究会・企業セミナー(名古屋）
- Data Source
  KAKENHI-PROJECT-16K18983
[Presentation] 胎生期海馬に存在する神経幹・前駆細胞の性質2017
- Author(s)
  柏木太一, 篠原広志, 塩田清二, 石龍徳
- Organizer
  第122回日本解剖学会総会・全国学術集会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] The granule cells are generated by various cell types depend on several cellular migrating pathways during the developmental stages.2017
- Author(s)
  Shinohara H, Seki T
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] Migration　Behavior of Neural stem/progenitor Cells in the Developing Dentate Gyrus2017
- Author(s)
  篠原広志,石龍徳
- Organizer
  第122回日本解剖学会総会・全国学術集会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] 海馬顆粒細胞は発生時期に応じて異なる経路に依存したタイプの異なる細胞によって形成される2017
- Author(s)
  篠原広志、石龍徳
- Organizer
  第40回日本神経科学大会（幕張メッセ）
- Data Source
  KAKENHI-PROJECT-16K18983
[Presentation] 海馬歯状回のつくられ方：神経前駆細胞の発生過程に依存した移動パターン変化2017
- Author(s)
  篠原広志
- Organizer
  第2回春の神経発生研究会（東北大学）
- Data Source
  KAKENHI-PROJECT-16K18983
[Presentation] Various Cell Types Construct The Dentate Gyrus During Development2016
- Author(s)
  Shinohara H，Yamamoto Y，Seki T
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] 細胞移動を基軸とする海馬歯状回形成のメカニズム探索2016
- Author(s)
  篠原広志, 塩田清二, 石龍徳
- Organizer
  第121回日本解剖学会総会・全国学術集会
- Place of Presentation
  福島
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25430041
[Presentation] Intracellular trafficking of the CXCR4 molecules in the neural progenitors during formation of hippocampal granule cell layer2016
- Author(s)
  Yamamoto Y, Shinohara H, Kashiwagi T, Sato T, Matsue K, Shioda S, Seki T
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-16K07033
[Presentation] Cell-tracing analysis for progenitor cell migration in the embryonic dentate gyrus2015
- Author(s)
  Shinohara H, Shioda S, Seki T
- Organizer
  日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25430041
[Presentation] Cell-tracing analysis for progenitor cell migraion in the embryonic dentate gyrus2015
- Author(s)
  Shinohara H, Shioda S, Seki T
- Organizer
  The 120th Annual meeting of the Japanese association of anatomists
- Place of Presentation
  神戸
- Year and Date
  2015-03-24
- Data Source
  KAKENHI-PROJECT-25430041
[Presentation] Cell-tracing analysis for progenitor cell migration in the embryonic dentate gyrus2014
- Author(s)
  Shinohara H, Sato T, Toda K, Shioda S, Seki T
- Organizer
  The 37th Annual meeting of the Japan neuroscience society
- Place of Presentation
  横浜
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PROJECT-25430041
[Presentation] 胎生期海馬神経前駆細胞の移動解析
- Author(s)
  篠原広志、佐藤亨、戸田景子、塩田清二
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25430041
[Presentation] 細胞移動を基軸とする海馬枝上回形成のメカニズム探索
- Author(s)
  篠原広志、佐藤亨、戸田景子、塩田清二、石龍徳
- Organizer
  第119回日本解剖学会総会・全国学術集会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-25430041

1. Seki Tatsunori (20175417)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. Kashiwagi Taichi (10398232)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. 權田裕子 (60424181)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Kurosawa Yuko (90623108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 涌井佐和子 (00360959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 大黒多希子 (30767249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 浜岡隆文 (70266518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山下典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shinohara Hiroshi 篠原 広志

Research Projects

Research Products

Co-Researchers

起源の異なる海馬神経幹細胞がもたらす成体期神経新生および歯状回形成機構の比較解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reexamination of adult neurogenesis in the marmoset and human hippocampus

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A New Approach for Anti-Aging/Neurodegenerative Disease Therapy via Inhibition of Brain Atrophy: Using Creatine Derivatives

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of embryonic to adult neurogenesis with a special emphasis on microenvironmental signal

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Search for the origin of adult neural stem cell and analysis of granule cell layer formation in the dentate gyrusPrincipal Investigator

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Analysis of embryonic-to-adult transition in neural progenitors of the hippocampal granule cells

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[Journal Article] PSmad3+/Olig2? expression defines a subpopulation of gfap-GFP+/Sox9+ neural progenitors and radial glia-like cells in mouse dentate gyrus through embryonic and postnatal development2023

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[Journal Article] The polarity and properties of radial glia-like neural stem cells are altered by seizures with status epilepticus: Study using an improved mouse pilocarpine model of epilepsy2020

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[Journal Article] Non-radial tortuous migration with cell polarity alterations of newly generated granule neurons in the neonatal rat dentate gyrus2019

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[Journal Article] 1次繊毛形成の正常化はダウン症候群の治療標的に成り得るか？2019

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NAID

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[Journal Article] The role of Pax6 in brain development and its impact on pathogenesis of autism spectrum disorder2018

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[Journal Article] Dynamics and function of CXCR4 in formation of the granule cell layer during hippocampal development2017

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[Presentation] Temporally regulated expression patterns of Zeb1, Scratch2, and Nkx6-2 in the granule neuronal progenitors of developing mouse dentate gyrus2024

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[Presentation] Development of Olig2+/Sox9+ astrocytes in mouse dentate gyrus2024

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[Presentation] 移動経路や性質が異なる神経前駆細胞によって海馬歯状回は形成される2023

Author(s)

Shinohara Hiroshi 篠原広志