Kiyomitsu Tomomi 清光智美

… Alternative Names

KIYOMITSU Tomomi 清光智美

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Researcher Number	10503443
Other IDs
Affiliation (Current)	2025: 沖縄科学技術大学院大学, 細胞分裂動態ユニット, 准教授
Affiliation (based on the past Project Information) *help	2025: 沖縄科学技術大学院大学, 細胞分裂動態ユニット, 准教授 2020 – 2023: 沖縄科学技術大学院大学, 細胞分裂動態ユニット, 准教授 2018 – 2019: 名古屋大学, 理学研究科, 講師 2016 – 2017: 名古屋大学, 理学研究科, 助教 2014 – 2015: 名古屋大学, 理学(系)研究科(研究院), 助教 2008 – 2009: Kyoto University, 生命科学研究科, 研究員
Review Section/Research Field	Principal Investigator Cell biology / Basic Section 44010:Cell biology-related / Transformative Research Areas, Section (III) / Basic Section 44010:Cell biology-related / Biological Sciences / Molecular biology Except Principal Investigator Cell biology
Keywords	Principal Investigator 紡錘体 / NuMA / ダイニン / オーキシン誘導デグロン / Ran-GTP / 細胞分裂 / 光遺伝学 / 細胞生物 / RCC1 / 紡錘体配置 … More / 初期胚 / AID法 / メダカ / dynein / 等分裂 / 光操作 / ゲノム編集 / Ran / AID / HURP / Ran-GTP濃度勾配 / 分裂期特異的分解 / オーキシン誘導デグロン法 / 紡錘体極 / Plk1 / 非対称化 / 分裂期中心体 / RanGTP / 染色体派生シグナル / Bubl / Heterochromatin Protein-1(HP1) / hMis14 / hMis12複合体 / ブリンキン / yeast 2 hybrid法 / 分裂期チェックポイント / M期チェックポイント / 動原体 / 染色体分配 … More Except Principal Investigator 細胞 Less

Coordination of the mitotic spindle assembly by three mirotubule-nucleation pathwaysPrincipal Investigator
- Principal Investigator
  
  清光智美
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
Mechanisms of mitotic spindle assembly and remodeling in medaka early embryosPrincipal Investigator
- Principal Investigator
  
  清光智美
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
Cell cycle-dependent dynein adaptor switchingPrincipal Investigator
- Principal Investigator
  
  清光智美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
Understanding functional structure of dynein complexes/clusters required for mitotic spindle assembly and positioningPrincipal Investigator
- Principal Investigator
  
  Kiyomitsu Tomomi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
紡錘体牽引力を生み出すダイニンクラスターの試験管内再構成と構造解析Principal Investigator
- Principal Investigator
  
  清光智美
- Project Period (FY)
  2018
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
Defining the mechanisms of equal-sized cell division using advanced genetic and optogenetic technologiesPrincipal Investigator
- Principal Investigator
  
  Kiyomitsu Tomomi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
  Nagoya University
Elucidating the mechanisms of spindle formation through systematic gene deletion
- Principal Investigator
  
  Goshima Gohta
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
AID-mediated acute protein degradation system in human mitotic cellsPrincipal Investigator
- Principal Investigator
  
  Kiyomitsu Tomomi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
紡錘体極派生シグナルの非対称化操作による細胞の非対称化の検証Principal Investigator
- Principal Investigator
  
  清光智美
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Coordinated regulation of spindle positioning and membrane elongation by chromosome-derived signalsPrincipal Investigator
- Principal Investigator
  
  Kiyomitsu Tomomi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
The role of kinetochore protein, Blinkin, for the localization and function of mitotic checkpoint proteinsPrincipal Investigator
- Principal Investigator
  
  KIYOMITSU Tomomi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Molecular biology
- Research Institution
  Kyoto University

All 2021 2020 2019 2018 2017 2016 2015 2014 2010 2009 2008

All Journal Article Presentation Book

[Book] 実験医学-クローズアップ実験法2019
- Author(s)
  清光智美
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17H05002
[Journal Article] Ran-GTP Is Non-essential to Activate NuMA for Mitotic Spindle-Pole Focusing but Dynamically Polarizes HURP Near Chromosomes2021
- Author(s)
  Tsuchiya Kenta、Hayashi Hisato、Nishina Momoko、Okumura Masako、Sato Yoshikatsu、Kanemaki Masato T.、Goshima Gohta、Kiyomitsu Tomomi
- Journal Title
  
  Current Biology
  
  Volume: 31 Issue: 1 Pages: 115-127.e3
- DOI
  10.1016/j.cub.2020.09.091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-19H05670, KAKENHI-PUBLICLY-20H05396, KAKENHI-PROJECT-17H01431, KAKENHI-PROJECT-17H05002, KAKENHI-PROJECT-21H04719
[Journal Article] Importin-β targets HURP to kinetochore-fibers in coordination with Ran-GTP in human mitotic cells2018
- Author(s)
  Tsuchiya K, Hayashi H, Nishina M, Okumura M, Kanemaki MT, Goshima G, Kiyomitsu T
- Journal Title
  
  bioRxiv
  
  Volume: 1 Pages: 1-31
- DOI
  10.1101/473538
- Open Access
- Data Source
  KAKENHI-PROJECT-17H05002, KAKENHI-PROJECT-16K14721, KAKENHI-PROJECT-17H01431
[Journal Article] Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble2018
- Author(s)
  Okumura Masako、Natsume Toyoaki、Kanemaki Masato T、Kiyomitsu Tomomi
- Journal Title
  
  eLife
  
  Volume: 7 Pages: 1-24
- DOI
  10.7554/elife.36559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04719, KAKENHI-PROJECT-18H02170, KAKENHI-PROJECT-17H05002, KAKENHI-PROJECT-17K15068
[Journal Article] Analyzing Spindle Positioning Dynamics in Cultured Cells2017
- Author(s)
  Tomomi Kiyomitsu
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1413 Pages: 1-15
- DOI
  10.1007/978-1-4939-3542-0_15
- ISBN
  9781493935406, 9781493935420
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26840063
[Journal Article] Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP22017
- Author(s)
  Tungadi Elsa A.、Ito Ami、Kiyomitsu Tomomi、Goshima Gohta
- Journal Title
  
  Journal of Cell Science
  
  Volume: 130 Issue: 21 Pages: 3676-3684
- DOI
  10.1242/jcs.203703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01431
[Journal Article] Mechanisms of daughter cell-size control during cell division2014
- Author(s)
  Tomomi Kiyomitsu
- Journal Title
  
  Trends in Cell Biology
  
  Volume: S0962-8924(14) Issue: 5 Pages: 00213-22
- DOI
  10.1016/j.tcb.2014.12.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26840063
[Journal Article] Inner centromere formation requires hMis14, a trident kinetochore prote in that specifically recruits HP1 to human chromosomes2010
- Author(s)
  Tomomi Kiyomitsu, Osamu Iwasaki, Chikashi Obuse, Mitsuhiro Yanagida
- Journal Title
  
  The Journal of Cell Biology 188
  
  Pages: 791-807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870023
[Journal Article] Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes2010
- Author(s)
  Tomomi Kiyomitsu, Osamu Iwasaki, Chikashi Obuse, Mitsuhiro Yanagida
- Journal Title
  
  The Journal of Cell Biology誌 vol.188
  
  Pages: 791-807
- NAID
  120002949726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870023
[Journal Article] ブリンキン-紡錘体形成チェックポイントと微小管結合に必須なキネトコア蛋白質-2009
- Author(s)
  清光智美、小布施力史、柳田充弘
- Journal Title
  
  蛋白質核酸酵素 vol54-4
  
  Pages: 421-426
- Data Source
  KAKENHI-PROJECT-20870023
[Journal Article] The crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochores2009
- Author(s)
  Bolanos-Garcia VM, Kiyomitsu T, D'Arcy S, Chirgadze DY, Grossmann JG, Matak-Vinkovic D, Venkitaraman AR, Yanagida M, Robinson CV, Blundell TL
- Journal Title
  
  Structure 17
  
  Pages: 105-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870023
[Journal Article] The crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochores2009
- Author(s)
  Bolanos-Garcia, V.M., Kiyomitsu, T., D'Arcy, S., Chirgadze, D.Y., Grossmann, J.G., Matak-Vinkovic, D., Venkitaraman, A.R., Yanagida, M., Robinson, C.V., Blundell, T.L.
- Journal Title
  
  Structure誌 vol17
  
  Pages: 105-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870023
[Journal Article] ブリンキン・紡錘体形成チェックポイントと微小管結合に必須なキネトコア蛋白質・2009
- Author(s)
  清光智美, 小布施力史, 柳田充弘
- Journal Title
  
  蛋白質核酸酵素 54-4
  
  Pages: 421-426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870023
[Presentation] Mechanisms of Ran-based mitotic spindle assembly revealed by auxin-mediated rapid protein knock-down2020
- Author(s)
  Tomomi Kiyomitsu
- Organizer
  The 43rd Annual Meeting of the Molecular Biology Society of Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05002
[Presentation] 光操作と急速分解、二刀流でダイニンの分裂期機能に迫る2019
- Author(s)
  清光智美
- Organizer
  分子モーター討論会
- Invited
- Data Source
  KAKENHI-PROJECT-17H05002
[Presentation] The development of mitosis-specific rapid protein-degradation assays in human cells2019
- Author(s)
  Tomomi Kiyomitsu
- Organizer
  EMBO/EMBL symposium, Seeing is Believing
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05002
[Presentation] The development of mitosis-specific rapid protein-degradation assays in human cells2019
- Author(s)
  清光智美
- Organizer
  EMBO | EMBL Symposium: Seeing is Believing - Imaging the Molecular Processes of Life
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01431
[Presentation] Optogenetic reconstitution reveals that Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble.2018
- Author(s)
  Kiyomitsu T
- Organizer
  EMBO microtubule meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05002
[Presentation] Mechanisms of dynein-based force generation at the cell cortex and spindle poles during metaphase2018
- Author(s)
  Kiyomitsu T
- Organizer
  The 41st Annual Meeting of the Molecular Biology Society of Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14721
[Presentation] Importin-β recruits HURP to k-fibers in cooperation with Ran-GTP to form proper metaphase spindle2018
- Author(s)
  Kenta Tsuchiya, Hisato Hayashi, Momoko Nishina, Masako Okumura, Masato T. Kanemaki, Gohta Goshima, Tomomi Kiyomitsu
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H01431
[Presentation] Mechanisms of dynein-based force generation at the cell cortex and spindle poles during metaphase2018
- Author(s)
  Kiyomitsu T
- Organizer
  The 41st Annual Meeting of the Molecular Biology Society of Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05002
[Presentation] ヒト細胞質ダイニン複合体による紡錘体二極構造の維持2016
- Author(s)
  仁科桃子、夏目豊彰、鐘巻将人、清光智美
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-16K14721
[Presentation] 染色体派生シグナルによる紡錘体配置の制御2015
- Author(s)
  清光智美
- Organizer
  新学術領域クロマチン動構造若手の会
- Place of Presentation
  早稲田大学
- Year and Date
  2015-07-29
- Invited
- Data Source
  KAKENHI-PROJECT-26840063
[Presentation] 細胞が等分裂する仕組みとその意義の理解に向けて2015
- Author(s)
  清光智美
- Organizer
  第24回日本バイオイメージング学会
- Place of Presentation
  東京理科大学
- Year and Date
  2015-09-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01210
[Presentation] Mutual dependency between kinetochore and inner centromere assemblies2009
- Author(s)
  Tomomi Kiyomitsu
- Organizer
  The 24th Naito Conference on " Nuclear dynamics and RNA(II)"
- Place of Presentation
  シャトレーゼガトーキングダム札幌
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20870023
[Presentation] キネトコアとインナーセントロメア形成の相互依存性2009
- Author(s)
  清光智美
- Organizer
  先端生命科学シンポジウム染色体の分子構築
- Place of Presentation
  北海道大学
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-20870023
[Presentation] Inner centromere formation requires trident-binding kinetochore protein2009
- Author(s)
  Kiyomitsu, T., Iwasaki, O., Obuse, C., Yanagida, M.
- Organizer
  hMis14, that specifically recruits HP1 in human chromosome
- Place of Presentation
  Spindle Assembly and Function, Lucca, Italy
- Data Source
  KAKENHI-PROJECT-20870023
[Presentation] キネトコアとインナーセントロメア形成の相互依存性2009
- Author(s)
  清光智美
- Organizer
  先端生命科学シンポジウム染色体の分子構築
- Place of Presentation
  北海道大学
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-20870023
[Presentation] Mutual dependency between kinetochore and inner centromere assemblies2009
- Author(s)
  清光智美
- Organizer
  The 24^<th> Naito Conference on "Nuclear dynamics and RNA (II)"
- Place of Presentation
  シャトレーゼガトーキングダム札幌
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20870023
[Presentation] ヒトキネトコアタンパク質hMis14とHP1の直接結合がM期染色体のインナーセントロメア形成に必要である2009
- Author(s)
  清光智美
- Organizer
  第8回核ダイナミクス研究会
- Place of Presentation
  ラフォーレ修善時静岡県伊豆市大平1529
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20870023
[Presentation] Human kinetochore protein, blinkin/AF15q14, is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR12008
- Author(s)
  Tomomi Kiyomitsu, Chikashi Obuse, Mitsuhiro Yanagida
- Organizer
  CONFERENCES JACQUES-MONOD, The cell cycle and genomic stability
- Place of Presentation
  France, Roscoff
- Year and Date
  2008-04-27
- Data Source
  KAKENHI-PROJECT-20870023

1. Goshima Gohta (20447840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. VAN TOORN MARVIN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鐘巻将人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kiyomitsu Tomomi 清光 智美

KIYOMITSU Tomomi 清光 智美

Research Projects

Research Products

Co-Researchers

Coordination of the mitotic spindle assembly by three mirotubule-nucleation pathwaysPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of mitotic spindle assembly and remodeling in medaka early embryosPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell cycle-dependent dynein adaptor switchingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding functional structure of dynein complexes/clusters required for mitotic spindle assembly and positioningPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

紡錘体牽引力を生み出すダイニンクラスターの試験管内再構成と構造解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Defining the mechanisms of equal-sized cell division using advanced genetic and optogenetic technologiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidating the mechanisms of spindle formation through systematic gene deletion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

AID-mediated acute protein degradation system in human mitotic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

紡錘体極派生シグナルの非対称化操作による細胞の非対称化の検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Coordinated regulation of spindle positioning and membrane elongation by chromosome-derived signalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of kinetochore protein, Blinkin, for the localization and function of mitotic checkpoint proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 実験医学-クローズアップ実験法2019

Author(s)

Publisher

Data Source

[Journal Article] Ran-GTP Is Non-essential to Activate NuMA for Mitotic Spindle-Pole Focusing but Dynamically Polarizes HURP Near Chromosomes2021

Author(s)

Journal Title

DOI

Data Source

Kiyomitsu Tomomi 清光智美

KIYOMITSU Tomomi 清光智美