Kuzumaki Naoko 葛巻直子

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KUZUMAKI Naoko 葛巻直子

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Researcher Number	10507669
Other IDs
External Links
Affiliation (Current)	2025: 星薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 星薬科大学, 薬学部, 准教授 2016 – 2017: 星薬科大学, 薬学部, 講師 2014: 星薬科大学, 薬学部, 講師 2011 – 2013: 慶應義塾大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related / Pharmacology in pharmacy / Neurochemistry/Neuropharmacology / Anesthesiology/Resuscitation studies Except Principal Investigator Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator ドパミン神経 / iPS 細胞 / 知覚神経 / パーキンソン病 / 注意欠如・多動症 / 疼痛 / Dopamine 神経 / 慢性疼痛 / ADHD / ドパミン神経細胞 … More / 知覚神経細胞 / 線維筋痛症 / ドパミン / 神経科学 / ヒト iPS 細胞 / 中脳ドパミン神経 / エピジェネティクス / iPS 細胞 / 疾患特異的iPS 細胞 / メタボローム解析 / メタボローム / ゲフィチニブ耐性 / 非小細胞性肺がん / 非小細胞肺がん / 抗がん剤耐性 / GPCR / がん細胞 / オピオイド / 麻酔学 … More Except Principal Investigator トランスレーショナルリサーチ / 気分障害 / 自閉スペクトラム症 / 統合失調症 / 直接誘導ミクログリア様細胞（iMG） / 直接誘導ニューロン（iN） / iPS技術 / 再生医学 / 直接誘導ミクログリア様細胞 / 直接誘導ニューロン / iPS細胞 / ミクログリア Less

疾患分化細胞の複合的解析による"疼痛を伴う注意欠如・多動症"の分子病態解明Principal Investigator
- Principal Investigator
  
  葛巻直子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hoshi University
Analysis of the pain mechanism and treatment of fibromyalgia by the application of disease cell differentiation technologiesPrincipal Investigator
- Principal Investigator
  
  Kuzumaki Naoko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hoshi University
Clarifying the underlying pathophysiology of neuropsychiatric disorders using human-tissues-directly-derived neuronal/glial cells: Reverse-Translational Study.
- Principal Investigator
  
  Kato Takahiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Kyushu University
Analysis of epigenetic modification in parkinson's disease patient-specific iPSCs-derived dopamine neuronsPrincipal Investigator
- Principal Investigator
  
  Kuzumaki Naoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Hoshi University
Multiple analysis of intracellular responases in intractable disease related to dopaminergic neuron vulnerability with the use of Parkinson's Disease specific iPS cellsPrincipal Investigator
- Principal Investigator
  
  KUZUMAKI Naoko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Hoshi University
  Keio University
Effect of opioids on tumor growth and stem cell differentiationPrincipal Investigator
- Principal Investigator
  
  KUZUMAKI Naoko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Keio University

All 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] がん疼痛緩和ケア2014
- Author(s)
  葛巻直子
- Total Pages
  6
- Publisher
  じほう
- Data Source
  KAKENHI-PROJECT-25830055
[Book] トワイクロス先生のがん緩和ケア処方薬-薬効・薬理と薬の使い方、4 中枢神経薬、抗うつ薬2012
- Author(s)
  葛巻直子 (分担翻訳)、監訳: 武田文和、鈴木勉
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23791731
[Book] オピオイドが示す多彩な生理応答: 血管新生やがん細胞増殖に及ぼす役割、ペインクリニック別冊秋号2012
- Author(s)
  葛巻直子、山水康平、濱田祐輔、長澤阿津実、山下潤、成田年
- Publisher
  新興交易
- Data Source
  KAKENHI-PROJECT-23791731
[Book] オピオイドが示す多彩な生理応答: 血管新生やがん細胞増殖に及ぼす役割2012
- Author(s)
  葛巻直子
- Total Pages
  8
- Publisher
  新興交易(株) 医学出版部
- Data Source
  KAKENHI-PROJECT-23791731
[Journal Article] Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson’s disease2019
- Author(s)
  Naoko Kuzumaki, Yukari Suda, Chizuru Iwasawa, Michiko Narita, Takefumi Sone, Moe Watanabe, Aya Maekawa, Takuya Matsumoto, Wado Akamatsu, Katsuhide Igarashi, Hideki Tamura, Hideyuki Takeshima, Vivianne L. Tawfik, Toshikazu Ushijima, Nobutaka Hattori, Hideyuki Okano and Minoru Narita
- Journal Title
  
  Brain
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08280
[Journal Article] Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction.2018
- Author(s)
  Suda Y, Kuzumaki N, Sone T, Narita M, Tanaka K, Hamada Y, Iwasawa C, Shibasaki M, Maekawa A, Matsuo M, Akamatsu W, Hattori N, Okano H, Narita M.
- Journal Title
  
  Mol Brain.
  
  Volume: 11 Issue: 1 Pages: 6-6
- DOI
  10.1186/s13041-018-0349-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07070, KAKENHI-PROJECT-16K08280, KAKENHI-PROJECT-16K09677, KAKENHI-PROJECT-15K06924, KAKENHI-PUBLICLY-17H05706
[Journal Article] Effect of ghrelin on the motor deficit caused by the ablation of nigrostriatal dopaminergic cells or the inhibition of striatal dopamine receptors.2018
- Author(s)
  Suda Y, Kuzumaki N, Narita M, Hamada Y, Shibasaki M, Tanaka K, Tamura H, Kawamura T, Kondo T, Yamanaka A, Narita M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 496 Issue: 4 Pages: 1102-1108
- DOI
  10.1016/j.bbrc.2018.01.145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07070, KAKENHI-PROJECT-16K08280, KAKENHI-PUBLICLY-16H01271, KAKENHI-PUBLICLY-17H05563
[Journal Article] Parkin absence accelerates microtubule aging in dopaminergic neurons2018
- Author(s)
  Cartelli D, Amadeo A, Calogero AM, Casagrande FVM, De Gregorio C, Gioria M, Kuzumaki N, Costa I, Sassone J, Ciammola A, Hattori N, Okano H, Goldwurm S, Roybon L, Pezzoli G, Cappelletti G
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 61 Pages: 66-74
- DOI
  10.1016/j.neurobiolaging.2017.09.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08280
[Journal Article] Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons.2017
- Author(s)
  Suzuki S, Akamatsu W, Kisa F, Sone T, Ishikawa KI, Kuzumaki N, Katayama H, Miyawaki A, Hattori N, Okano H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 489 Issue: 1 Pages: 88-93
- DOI
  10.1016/j.bbrc.2016.12.188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117007, KAKENHI-PROJECT-15K06924, KAKENHI-PROJECT-16K09677, KAKENHI-PROJECT-16K19524, KAKENHI-PROJECT-16K08280
[Journal Article] Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells2016
- Author(s)
  Matsumoto T, Fujimori K, Andoh-Noda T, Ando T, Kuzumaki N, Toyoshima M, Tada H, Imaizumi K, Ishikawa M, Yamaguchi R, Isoda M, Zhou Z, Sato S, Kobayashi T, Ohtaka M, Nishimura K, Kurosawa H, Yoshikawa T, Takahashi T, Nakanishi M, Ohyama M, Hattori N, Akamatsu W, Okano H.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 6 Issue: 3 Pages: 422-35
- DOI
  10.1016/j.stemcr.2016.01.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06780, KAKENHI-PROJECT-15K09849, KAKENHI-PROJECT-15K15041, KAKENHI-PROJECT-26830018, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-24116002, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-26870074, KAKENHI-ORGANIZER-24116001, KAKENHI-PROJECT-16K08280
[Journal Article] Changes in circadian rhythm for mRNA expression of melatonin 1A and 1B receptors in the hypothalamus under a neuropathic pain-like state.2014
- Author(s)
  Odo M, Koh K, Takada T, Yamashita A, Narita M, Kuzumaki N, Ikegami D, Sakai H, Iseki M, Inada E, Narita M.
- Journal Title
  
  Synapse
  
  Volume: 68 Issue: 4 Pages: 153-158
- DOI
  10.1002/syn.21728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22390300, KAKENHI-PROJECT-24790582, KAKENHI-PROJECT-25830055, KAKENHI-PROJECT-26293346, KAKENHI-PROJECT-26640015
[Journal Article] Astrocytic activation in the anterior cingulate cortex is critical for sleep disorder under neuropathic pain.2014
- Author(s)
  Yamashita A, Hamada A, Suhara Y, Kawabe R, Yanase M, Kuzumaki N, Narita M, Matsui R, Okano H, Narita M.
- Journal Title
  
  Synapse
  
  Volume: 68 Issue: 6 Pages: 235-247
- DOI
  10.1002/syn.21733
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22390300, KAKENHI-PROJECT-24390151, KAKENHI-PROJECT-25830055, KAKENHI-PROJECT-26293346, KAKENHI-PROJECT-26640015
[Journal Article] Kappa-Opioids inhibit tumor angiogenesis by suppressing VEGF signaling.2013
- Author(s)
  Yamamizu K, Furuta S, Hamada Y, Yamashita A, Kuzumaki N, Narita M, Doi K, Katayama S, Nagase H, Yamashita JK, Narita M.
- Journal Title
  
  Scientific Reports
  
  Volume: 3 Issue: 1 Pages: 3213-3213
- DOI
  10.1038/srep03213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390197, KAKENHI-PROJECT-25830055, KAKENHI-PROJECT-26293346
[Journal Article] Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain.2013
- Author(s)
  Imai S, Ikegami D, Yamashita A, Shimizu T, Narita M, Niikura K, Furuya M, Kobayashi Y, Miyashita K, Okutsu D, Kato A, Nakamura A, Araki A, Omi K, Nakamura M, James Okano H, Okano H, Ando T, Takeshima H, Ushijima T, Kuzumaki N, Suzuki T, Narita M.
- Journal Title
  
  Brain
  
  Volume: 136 Issue: 3 Pages: 828-843
- DOI
  10.1093/brain/aws330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390300, KAKENHI-PROJECT-24390151, KAKENHI-PROJECT-24791627, KAKENHI-PROJECT-25830055
[Journal Article] Effect of κ-opioid receptor agonist on the growth of non-small cell lung cancer (NSCLC) cells.2012
- Author(s)
  Kuzumaki N, Suzuki A, Narita M, Hosoya T, Nagasawa A, Imai S, Yamamizu K, Morita H, Nagase H, Okada Y, Okano HJ, Yamashita JK, Okano H, Suzuki T, Narita M.
- Journal Title
  
  Br J Cancer.
  
  Volume: 106 Pages: 1148-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791731
[Journal Article] Effect of k-opioid receptor agonist on the growth of non-small cell lung cancer (NSCLC) cells2012
- Author(s)
  Kuzumaki N, Suzuki A, Narita M, Hosoya T, Nagasawa A, Imai S, Yamamizu K, Morita H, Nagase H, Okada Y, Okano HJ, Yamashita JK, Okano H, Suzuki T, Narita M
- Journal Title
  
  Br J Cancer
  
  Volume: 106(Epub 2012 Feb 16) Issue: 6 Pages: 1148-1152
- DOI
  10.1038/bjc.2011.574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390239, KAKENHI-PUBLICLY-23110516, KAKENHI-PUBLICLY-23122509, KAKENHI-PROJECT-23650194, KAKENHI-PROJECT-23659415, KAKENHI-PROJECT-23689017, KAKENHI-PROJECT-23791731, KAKENHI-PROJECT-24390197
[Journal Article] Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer.2012
- Author(s)
  Kuzumaki N, Suzuki A, Narita M, Hosoya T, Nagasawa A, Imai S, Yamamizu K, Morita H, Suzuki T, Okada Y, Okano HJ, Yamashita JK, Okano H, Narita M.
- Journal Title
  
  PLoS One.
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791731
[Journal Article] Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer.2012
- Author(s)
  Kuzumaki N
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 10 Pages: e44368-e44368
- DOI
  10.1371/journal.pone.0044368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650194, KAKENHI-PROJECT-23689017, KAKENHI-PROJECT-23791731, KAKENHI-PROJECT-24390197, KAKENHI-PUBLICLY-23110516
[Journal Article] The kappa opioid system regulates endothelial cell differentiation and pathfinding in vascular development2011
- Author(s)
  Yamamizu K, Furuta S, Katayama S, Narita M, Kuzumaki N, Imai S, Nagase H, Suzuki T, Narita M, Yamashita JK
- Journal Title
  
  Blood(表紙)
  
  Volume: 118 Issue: 3 Pages: 775-785
- DOI
  10.1182/blood-2010-09-306001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390239, KAKENHI-PUBLICLY-23122509, KAKENHI-PROJECT-23659415, KAKENHI-PROJECT-23791731
[Presentation] 神経難治性疾患の緩和を目指したリバーストランスレーショナルリサーチの実践2023
- Author(s)
  葛巻直子、須田雪明、岡野栄之、服部信孝、成田年
- Organizer
  第96回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09082
[Presentation] 難治性疼痛疾患解明に向けたヒト疾患 iPS 細胞由来神経サブタイプの横断的研究に基づいた表現系解析2022
- Author(s)
  葛巻直子, 須田雪明, 加藤隆弘, 岡野栄之, 成田年
- Organizer
  第 95 回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K09384
[Presentation] 線維筋痛症の分子病態解析：複数の疾患由来分化神経細胞を使用した統合的評価の確立2021
- Author(s)
  葛巻直子, 須田雪明, 石川充, 加藤隆弘, 成田道子, 田中謙一, 濱田祐輔, 細井昌子, 岡野栄之, 成田年
- Organizer
  第43回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-19K09384
[Presentation] 線維筋痛症病態解明を目指した疾患特異的 iPS 細胞分化誘導技術の応用2021
- Author(s)
  葛巻直子, 須田雪明, 加藤隆弘, 岡野栄之, 成田年
- Organizer
  第55回日本ペインクリニック学会
- Data Source
  KAKENHI-PROJECT-19K09384
[Presentation] 難治性疼痛への複合的神経機能変容の関与－ iPS 細胞を用いた線維筋痛症の病態解析から考える2021
- Author(s)
  葛巻直子, 加藤隆弘, 細井昌子, 成田年
- Organizer
  第 14 回日本運動器疼痛学会
- Data Source
  KAKENHI-PROJECT-19K09384
[Presentation] iPS 細胞からの分化誘導技術ならびにリバーストランスレーショナルニューロサイエンスリサーチを応用した難治性神経疾患の解明研究2020
- Author(s)
  葛巻直子、須田雪明、加藤隆弘、岡野栄之、成田　年
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K09384
[Presentation] Changes in the expression of opioids and opioid receptors in the sensory neurons of fibromyalgia and Parkinson’s disease patients using disease-specific iPS cells2019
- Author(s)
  Kuzumaki N, Kagawa R, Ikeda Y, Suda Y, Iwasawa C, Kato T, Hattori N, Okano H, Narita M
- Organizer
  50th International narcotics research conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09384
[Presentation] Analysis of dopaminergic dysfunction-related molecules in the developmental stage of Parkinson's disease using human disease-specific iPS cells2017
- Author(s)
  葛巻直子, 須田雪明, 岩澤千鶴, 成田道子, 渡邉　萌, 田村英紀, 五十嵐勝秀, 牛島俊和, 服部信孝,岡野栄之, 成田年
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08280
[Presentation] ヒト疾患特異的 iPS 細胞技術を応用した難治性神経疾患のメカニズム解析2017
- Author(s)
  葛巻直子, 須田雪明, 成田道子, 岡野栄之, 成田年
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08280
[Presentation] パーキンソン病患者iPS 細胞由来神経細胞内の代謝変動解析2017
- Author(s)
  葛巻直子, 須田雪明, 岩澤千鶴, 成田年
- Organizer
  第47回日本神経精神薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K08280
[Presentation] ヒト疾患特異的iPS細胞を用いた神経・精神疾患メカニズムの解明に向けた多角的解析2017
- Author(s)
  葛巻直子, 須田雪明, 岩澤千鶴, 成田年
- Organizer
  第61回日本薬学会　関東支部大会
- Data Source
  KAKENHI-PROJECT-16K08280
[Presentation] Analysis of epigenetic changes in the pathology of Parkinson's disease using PARK2 patient-specific iPS cells2017
- Author(s)
  Suda Y, Kuzumaki N, Akamatsu S, Ishimi H, Iwasawa C, Narita M, Tamura H, Maekawa A, Sone T, Igarashi K, Takeshima H, Ushijima T, Hattori N, Okano H, Narita M.
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K08280
[Presentation] ヒト疾患特異的 iPS 細胞研究の最前線とリバーストランスレーショナルリサーチへの応用2017
- Author(s)
  葛巻直子, 須田雪明, 岩澤千鶴, 成田道子,岡野栄之, 成田年
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K08280
[Presentation] Multiple analysis for the DNA methylation changed in parkinson's disease specific iPSC-derived dopaminergic neurons2016
- Author(s)
  N. Kuzumaki, Y. Suda, K. Igarashi, M. Narita, H. Takeshima, T. Ushijima, N. Hattori, M. Suematsu, H. Okano, M. Narita
- Organizer
  ISSCR 2016 Annual meeting
- Place of Presentation
  サンフランシスコ
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08280
[Presentation] Analysis of changes in the expression of dopamine-related genes with epigenetic chenges in parkinson's disease-specific iPS cell-derived dopaminergic neurons2016
- Author(s)
  Y. Suda, N. Kuzumaki, M. Narita, K. Igarashi, H. Takeshima, T. Ushijima, N. Hattori, H. Okano, M. Narita
- Organizer
  ISSCR 2016 Annual meeting
- Place of Presentation
  サンフランシスコ
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08280
[Presentation] Hypomethylation of COMT gene promoter in Parkinson’s disease-specific iPS cell-derived dopaminergic neurons2016
- Author(s)
  Y. Suda，N. Kuzumaki，M. Narita，K. Igarashi，H. Takeshima，T. Ushijima，N. Hattori，H. Okano，M. Narita
- Organizer
  第 39回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K08280
[Presentation] ヒト疾患特異的 iPS 細胞を用いたパーキンソン病態下におけるエピゲノム変化の解析2016
- Author(s)
  須田雪明, 葛巻直子, 成田道子, 五十嵐勝秀, 竹島秀幸, 服部信孝, 岡野栄之, 牛島俊和, 成田年
- Organizer
  第10回日本エピジェネティクス研究会年会
- Place of Presentation
  大阪
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K08280
[Presentation] 多能性幹細胞の分化指向性におけるオピオイドの役割2014
- Author(s)
  葛巻直子
- Organizer
  第87 回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-25830055
[Presentation] Analyses of oxidative stress and metabolic dynamics in PARK2 iPSC-derived neurons2013
- Author(s)
  葛巻直子
- Organizer
  Inter national society for stem cell research 11th annual meeting
- Place of Presentation
  Boston Convention and Exhibition Center, Boston, MA, U.S.A
- Data Source
  KAKENHI-PROJECT-25830055
[Presentation] Role of opioid system in the cell differentiation from pluripotent stem cells2013
- Author(s)
  葛巻直子
- Organizer
  International Narcotics Research Conference 2013 meeting
- Place of Presentation
  Pullman Cairns International Hotel, North Queensland, Australia
- Data Source
  KAKENHI-PROJECT-25830055
[Presentation] Analyses of metabolic dynamics in iPSC-derived neurons from patient with familial Parkinson’s disease2013
- Author(s)
  葛巻直子
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-25830055
[Presentation] パーキンソン病患者 iPS 細胞由来神経細胞における酸化ストレス応答ならびに代謝動態の解析2013
- Author(s)
  葛巻直子
- Organizer
  Neuro 2013
- Place of Presentation
  国立京都国際会館・京都
- Data Source
  KAKENHI-PROJECT-25830055
[Presentation] G-蛋白共役型受容体によるゲフィチニブ耐性ヒト非小細胞肺がん増殖制御の可能性2012
- Author(s)
  葛巻直子、長澤阿津実、成田道子、濱田祐輔、岡野栄之、成田年
- Organizer
  第50回日本癌治療学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791731
[Presentation] Gefitinib 耐性ヒと非小細胞肺がん細胞の増殖抑制機構におけるG-protein coupled receptor (GPCR) の役割2012
- Author(s)
  葛巻直子、成田年
- Organizer
  第6回緩和医療薬学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23791731
[Presentation] G-蛋白共役型受容体によるゲフィチニブ耐性ヒト非小細胞肺がん増殖制御の可能性2012
- Author(s)
  葛巻直子
- Organizer
  第50 回癌治療学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23791731
[Presentation] Gefitinib 耐性ヒト非小細胞肺がん細胞の増殖制御機構におけるG-protein coupled receptor (GPCR) の役割2012
- Author(s)
  葛巻直子
- Organizer
  第 6 回緩和医療薬学会年会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23791731
[Presentation] オピオイドによるゲフィチニブ耐性ヒト非小細胞肺がん細胞の増殖制御2012
- Author(s)
  葛巻直子、長澤阿津実、成田道子、濱田祐輔、岡野栄之、成田年
- Organizer
  第32回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  JR 東京総合病院
- Data Source
  KAKENHI-PROJECT-23791731
[Presentation] G-protein coupled receptor (GPCR) を介したヒト非小細胞肺がん細胞の増悪化の制御機構2011
- Author(s)
  葛巻直子、岡野栄之、成田　年
- Organizer
  第 5 回緩和医療薬学会年会
- Place of Presentation
  幕張メッセ、千葉
- Data Source
  KAKENHI-PROJECT-23791731
[Presentation] ES 細胞からの神経幹細胞誘導における G-protein coupled receptor 発現の網羅的解析2011
- Author(s)
  葛巻直子、成田道子、濱田祐輔、長澤阿津実、岡田洋平、赤松和土、岡野ジェイムス洋尚、岡野栄之、成田　年
- Organizer
  第 34 回日本神経科学大会
- Place of Presentation
  パシフィコ横浜・神奈川
- Data Source
  KAKENHI-PROJECT-23791731
[Presentation] Suppression of cell growth and cancer stem cell properties of gefitinib-resistant non-small-cell lung cancer (NSCLC) cells by activation of delta-opioidergic system2011
- Author(s)
  Kuzumaki N, Suzuki A, Narita M, Yamamizu K, Nagasawa A, Okada Y, Okano HJ, Okano H, Yamashita JK, Suzuki T, Narita M
- Organizer
  The International nalcotic research conference 2011
- Place of Presentation
  Westin Diplomat Hotel, Florida, U.S.A
- Data Source
  KAKENHI-PROJECT-23791731
[Presentation] Changes in dopamine receptor expression in iPSC-derived neurons of patients with familial Parkinson’s disease
- Author(s)
  葛巻直子
- Organizer
  第37 回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25830055
[Presentation] ヒト疾患特異的 iPS 細胞技術を用いたドパミン神経依存性難治疾患における細胞内応答の多角的解析
- Author(s)
  葛巻直子
- Organizer
  第 88 回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-25830055

1. Kato Takahiro (70546465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 酒井康成 (10380396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 吉川武男 (30249958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SHIBASAKI Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 山下潤

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 成田年

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 佐藤栄人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 岡野栄之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kuzumaki Naoko 葛巻 直子

KUZUMAKI Naoko 葛巻 直子

Research Projects

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Co-Researchers

疾患分化細胞の複合的解析による"疼痛を伴う注意欠如・多動症"の分子病態解明Principal Investigator

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Analysis of the pain mechanism and treatment of fibromyalgia by the application of disease cell differentiation technologiesPrincipal Investigator

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Clarifying the underlying pathophysiology of neuropsychiatric disorders using human-tissues-directly-derived neuronal/glial cells: Reverse-Translational Study.

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Analysis of epigenetic modification in parkinson's disease patient-specific iPSCs-derived dopamine neuronsPrincipal Investigator

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Multiple analysis of intracellular responases in intractable disease related to dopaminergic neuron vulnerability with the use of Parkinson's Disease specific iPS cellsPrincipal Investigator

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Effect of opioids on tumor growth and stem cell differentiationPrincipal Investigator

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[Book] がん疼痛緩和ケア2014

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[Book] トワイクロス先生のがん緩和ケア処方薬-薬効・薬理と薬の使い方、4 中枢神経薬、抗うつ薬2012

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[Book] オピオイドが示す多彩な生理応答: 血管新生やがん細胞増殖に及ぼす役割、ペインクリニック別冊秋号2012

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[Book] オピオイドが示す多彩な生理応答: 血管新生やがん細胞増殖に及ぼす役割2012

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[Journal Article] Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson’s disease2019

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[Journal Article] Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction.2018

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[Journal Article] Effect of ghrelin on the motor deficit caused by the ablation of nigrostriatal dopaminergic cells or the inhibition of striatal dopamine receptors.2018

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[Journal Article] Parkin absence accelerates microtubule aging in dopaminergic neurons2018

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[Journal Article] Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons.2017

Author(s)

Kuzumaki Naoko 葛巻直子

KUZUMAKI Naoko 葛巻直子

[Presentation] 難治性疼痛への複合的神経機能変容の関与－ iPS 細胞を用いた線維筋痛症の病態解析から考える2021