SAKAMOTO Kei 坂本啓

… Alternative Names

Sakamorto Kei 坂本啓

坂本啓サカモトケイ

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Researcher Number	10528300
Other IDs
Affiliation (Current)	2025: 山口大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 山口大学, 大学院医学系研究科, 教授 2020 – 2022: 長崎大学, 医歯薬学総合研究科(医学系), 講師 2021: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2011: 公益財団法人朝日生命成人病研究所, 准教授
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related / Gastroenterology Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 宿主免疫 / 細菌叢 / 病原因子 / 細菌感染 / 薬剤耐性 / 感染症 / 免疫 / インフラマソーム / 食中毒 / 敗血症 … More Except Principal Investigator … More 合成生物学 / がん治療 / 生菌製剤 / 遺伝子改変細菌 Less

多剤耐性菌の制御法の開発に向けた腸内細菌目細菌の環境適応機構の解明Principal Investigator
- Principal Investigator
  
  坂本啓
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Yamaguchi University
難治性がん治療用デザイナー細菌の開発
- Principal Investigator
  
  向井英史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nagasaki University
Development of novel therapies for bacterial infections by linking the host immune mechanism with the action of the bacterial flora.Principal Investigator
- Principal Investigator
  
  Sakamorto Kei
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Yamaguchi University
  Nagasaki University
消化管癌の化学療法に対する治療抵抗能の獲得メカニズムと新規治療標的についての研究Principal Investigator
- Principal Investigator
  
  坂本啓
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The Institute for Adult Diseases Asahi Life Foundation

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] The clinical characteristics and molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) among very elderly people in Japan.2023
- Author(s)
  Mitsumoto-Kaseida F, Morinaga Y, Sasaki D, Ota K, Kaku N, Sakamoto K, Kosai K, Hasegawa H, Hayashi J, Yanagihara K.
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 23 Issue: 10 Pages: 744-749
- DOI
  10.1111/ggi.14664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07923
[Journal Article] The evaluation of a rapid microfluidic immunofluorescence antigen test in detecting the infectiousness of COVID-19 patients.2023
- Author(s)
  Ota K, Kodama H, Kawamoto Y, Sasaki D, Mitsumoto-Kaseida F, Sakamoto K, Kosai K, Hasegawa H, Takazono T, Izumikawa K, Mukae H, Tun MMN, Morita K, Yanagihara K.
- Journal Title
  
  BMC Infect Dis.
  
  Volume: 23 Issue: 1 Pages: 823-823
- DOI
  10.1186/s12879-023-08821-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07923
[Journal Article] Clinical and microbiological characteristics of bloodstream infection caused by Klebsiella pneumoniae harboring rmpA in Japanese adults.2023
- Author(s)
  Kikuchi S, Kosai K, Ota K, Mitsumoto-Kaseida F, Sakamoto K, Hasegawa H, Izumikawa K, Mukae H, Yanagihara K.
- Journal Title
  
  Sci Rep.
  
  Volume: 13 Issue: 1 Pages: 6571-6571
- DOI
  10.1038/s41598-023-33265-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07923, KAKENHI-PROJECT-20K08843
[Journal Article] Serological response to a third dose of SARS-CoV-2 vaccine according to previous infection history2023
- Author(s)
  Ota Kenji、Murakami Satoshi、Ishihara Kaori、Sasaki Daisuke、Usui Tetsuya、Mitsumoto-Kaseida Fujiko、Sakamoto Ke、Mukae Hiroshi、Kohno Shigeru、Yanagihara Katsunori
- Journal Title
  
  Vaccine: X
  
  Volume: 13 Pages: 100282-100282
- DOI
  10.1016/j.jvacx.2023.100282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08842, KAKENHI-PROJECT-21K16323, KAKENHI-PROJECT-23K07923
[Journal Article] Performance of the GeneSoC Rapid PCR System in Detection of SARS-CoV-2 from Saliva Specimens2023
- Author(s)
  Ota Kenji、Kurahara Ryo、Tsukamoto Chie、Kawamoto Yasuhide、Akamatsu Norihiko、Sasaki Daisuke、Mitsumoto-Kaseida Fujiko、Sakamoto Kei、Kosai Kosuke、Hasegawa Hiroo、Yamamoto Kazuko、Izumikawa Koichi、Mukae Hiroshi、Yanagihara Katsunori
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 11 Issue: 2 Pages: 1-3
- DOI
  10.1128/spectrum.03259-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08842, KAKENHI-PROJECT-21K16323, KAKENHI-PROJECT-23K07923
[Journal Article] The surveillance of colistin resistance and mobilized colistin resistance genes in multidrug-resistant Enterobacteriaceae isolated in Japan.2022
- Author(s)
  Kawamoto Y, Kaku N, Akamatsu N, Sakamoto K, Kosai K, Morinaga Y, Ohmagari N, Izumikawa K, Yamamoto Y, Mikamo H, Kaku M, Oishi K, Yanagihara K.
- Journal Title
  
  Int J Antimicrob Agents.
  
  Volume: 59 Issue: 1 Pages: 106480-106480
- DOI
  10.1016/j.ijantimicag.2021.106480
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08842
[Journal Article] BioFire FilmArray Pneumonia Panel enhances detection of pathogens and antimicrobial resistance in lower respiratory tract specimens2022
- Author(s)
  Kosai Kosuke、Akamatsu Norihiko、Ota Kenji、Mitsumoto-Kaseida Fujiko、Sakamoto Kei、Hasegawa Hiroo、Izumikawa Koichi、Mukae Hiroshi、Yanagihara Katsunori
- Journal Title
  
  Annals of Clinical Microbiology and Antimicrobials
  
  Volume: 21 Issue: 1 Pages: 24-24
- DOI
  10.1186/s12941-022-00512-8
- Data Source
  KAKENHI-PROJECT-20K08842
[Journal Article] Escherichia coli ST131 isolated from urological patients can acquire plasmid-mediated extended spectrum β-lactamase from other bacteria with high frequency2022
- Author(s)
  Kondo T, Sakamoto K, Morinaga Y, Miyata Y, Yanagihara K, Sakai H.
- Journal Title
  
  Int J Urol.
  
  Volume: - Issue: 6 Pages: 587-594
- DOI
  10.1111/iju.14845
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08842, KAKENHI-PROJECT-20K08843
[Journal Article] Detection of SARS-CoV-2 using qRT-PCR in saliva obtained from asymptomatic or mild COVID-19 patients, comparative analysis with matched nasopharyngeal samples.2021
- Author(s)
  Ota K, Yanagihara K, Sasaki D, Kaku N, Uno N, Sakamoto K, Kosai K, Miyazaki T, Hasegawa H, Fujita A, Tashiro M, Tanaka T, Izumikawa K, Ariyoshi K, Mukae H, Yasuda J, Morita K, Kohno S.
- Journal Title
  
  PLoS One.
  
  Volume: 16 Issue: 6 Pages: e0252964-e0252964
- DOI
  10.1371/journal.pone.0252964
- NAID
  120007168840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08842
[Journal Article] Rapid detection and surveillance of cfiA-positive Bacteroides fragilis using matrix-assisted laser desorption ionization time-of-flight mass spectrometry.2021
- Author(s)
  Kawamoto Y, Kosai K, Ota K, Uno N, Sakamoto K, Hasegawa H, Izumikawa K, Mukae H, Yanagihara K.
- Journal Title
  
  Anaerobe.
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08842
[Journal Article] Had COVID-19 spread in the community before the first confirmed case in Nagasaki, Japan?2021
- Author(s)
  Kaku N, Ota K, Sasaki D, Akamatsu N, Uno N, Sakamoto K, Kosai K, Hasegawa H, Izumikawa K, Mukae H, Yanagihara K.
- Journal Title
  
  Microbes Infect .
  
  Volume: - Issue: 4-5 Pages: 104812-104812
- DOI
  10.1016/j.micinf.2021.104812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08842
[Journal Article] Performance of anti-SARS-CoV-2 antibody testing in asymptomatic or mild COVID-19 patients: A retrospective study in outbreak on a cruise ship.2021
- Author(s)
  Kaku N, Nishimura F, Shigeishi Y, Tachiki R, Sakai H, Sasaki D, Ota K, Sakamoto K, Kosai K, Hasegawa H, Izumikawa K, Ariyoshi K, Mukae H, Yasuda J, Morita K, Kohno S, Yanagihara K.
- Journal Title
  
  PLoS One
  
  Volume: 16 Issue: 9 Pages: e0257452-e0257452
- DOI
  10.1371/journal.pone.0257452
- NAID
  120007178567
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08842
[Journal Article] Evaluation of a novel rapid TRC assay for the detection of influenza using nasopharyngeal swabs and gargle samples2021
- Author(s)
  Kaku N, Hashiguchi K, Akamatsu N, Wakigawa F, Matsuda J, Komaru K, Nakao T, Harada Y, Hara A, Uno N, Sakamoto K, Morinaga Y, Kitazaki T, Hasegawa H, Miyazaki T, Fukuda M, Izumikawa K, Mukae H, Yanagihara K.
- Journal Title
  
  Eur J Clin Microbiol Infect Dis
  
  Volume: - Issue: 8 Pages: 1743-1748
- DOI
  10.1007/s10096-021-04193-7
- NAID
  120007000285
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08842, KAKENHI-PROJECT-18H02728
[Journal Article] A novel macrolide, solithromycin suppresses mucin overexpression induced by Pseudomonas aeruginosa LPS in airway epithelial cells2020
- Author(s)
  Yasuhide Kawamoto , Yoshitomo Morinaga , Norihito Kaku , Naoki Uno , Kosuke Kosai , Kei Sakamoto , Hiroo Hasegawa , Katunori Yanagihara
- Journal Title
  
  J Infect Chemother .
  
  Volume: 9 Issue: 9 Pages: 1008-1010
- DOI
  10.1016/j.jiac.2020.06.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08842
[Journal Article] A Methodology for Assessing Tumor Clonality of Adult T Cell Leukemia/Lymphoma2020
- Author(s)
  Yamakawa T, Uno N, Sasaki D, Kaku N, Sakamoto K, Kosai K, Hasegawa H, Miyazaki Y, Yanagihara K.
- Journal Title
  
  Mol Ther Methods Clin Dev.
  
  Volume: 19 Pages: 463-473
- DOI
  10.1016/j.omtm.2020.10.015
- NAID
  120006980751
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08842, KAKENHI-PROJECT-18H02733
[Presentation] 腸内細菌叢を治療する時代　～過渡期における現状～2023
- Author(s)
  坂本　啓
- Organizer
  第70回　日本臨床検査医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K07923
[Presentation] Klebsiella Pneumoniaeの高病原性を規定する遺伝子の探索2023
- Author(s)
  倉田博基、坂本啓、坪内泰志、今村亮一、金子幸弘、柳原克紀
- Organizer
  第93回　日本感染症学会西日本地方会学術集会
- Data Source
  KAKENHI-PROJECT-23K07923
[Presentation] 黄色ブドウ球菌によるインフラマソーム活性化の新規経路の発見と治療標的としての可能性について2022
- Author(s)
  坂本啓
- Organizer
  感染症学会西日本学術集会
- Data Source
  KAKENHI-PROJECT-20K08842
[Presentation] 抗菌薬非依存的な新規治療戦略によるMRSA感染症に対する実験的治療2022
- Author(s)
  坂本啓
- Organizer
  MRSAフォーラム
- Data Source
  KAKENHI-PROJECT-20K08842
[Presentation] 嫌気性菌　～体内の Majority 達～2022
- Author(s)
  坂本啓
- Organizer
  感染症学会西日本学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08842
[Presentation] 黄色ブドウ球菌の感染によるインフラマソーム活性化の新経路の探索2021
- Author(s)
  坂本　啓
- Organizer
  日本感染症学会西日本地方会学術集会
- Data Source
  KAKENHI-PROJECT-20K08842
[Presentation] 腸内細菌叢による感染防御機構～基礎研究から臨床応用まで～2020
- Author(s)
  坂本　啓
- Organizer
  第90回日本感染症学会西日本地方会学術集会・第63回日本感染症学会中日本地方会学術集会・第68回日本化学療法学会西日本支部総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08842

1. 向井英史 (60570885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 片岡洋祐 (40291033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 櫻井文教 (70370939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 柳原克紀 (40315239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

SAKAMOTO Kei 坂本 啓

Sakamorto Kei 坂本 啓

坂本 啓 サカモト ケイ

Research Projects

Research Products

Co-Researchers

多剤耐性菌の制御法の開発に向けた腸内細菌目細菌の環境適応機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

難治性がん治療用デザイナー細菌の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel therapies for bacterial infections by linking the host immune mechanism with the action of the bacterial flora.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

消化管癌の化学療法に対する治療抵抗能の獲得メカニズムと新規治療標的についての研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The clinical characteristics and molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) among very elderly people in Japan.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The evaluation of a rapid microfluidic immunofluorescence antigen test in detecting the infectiousness of COVID-19 patients.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical and microbiological characteristics of bloodstream infection caused by Klebsiella pneumoniae harboring rmpA in Japanese adults.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serological response to a third dose of SARS-CoV-2 vaccine according to previous infection history2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Performance of the GeneSoC Rapid PCR System in Detection of SARS-CoV-2 from Saliva Specimens2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The surveillance of colistin resistance and mobilized colistin resistance genes in multidrug-resistant Enterobacteriaceae isolated in Japan.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BioFire FilmArray Pneumonia Panel enhances detection of pathogens and antimicrobial resistance in lower respiratory tract specimens2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Escherichia coli ST131 isolated from urological patients can acquire plasmid-mediated extended spectrum β-lactamase from other bacteria with high frequency2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of SARS-CoV-2 using qRT-PCR in saliva obtained from asymptomatic or mild COVID-19 patients, comparative analysis with matched nasopharyngeal samples.2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Rapid detection and surveillance of cfiA-positive Bacteroides fragilis using matrix-assisted laser desorption ionization time-of-flight mass spectrometry.2021

Author(s)

Journal Title

Data Source

SAKAMOTO Kei 坂本啓

Sakamorto Kei 坂本啓

坂本啓サカモトケイ

[Presentation] 腸内細菌叢を治療する時代　～過渡期における現状～2023

[Presentation] 黄色ブドウ球菌によるインフラマソーム活性化の新規経路の発見と治療標的としての可能性について2022

[Presentation] 嫌気性菌　～体内の Majority 達～2022