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Yamaguchi Hiroshi  山口 裕嗣

… Alternative Names

YAMAGUCHI Hiroshi  山口 裕嗣

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Researcher Number 10542970
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-4323-1282
Affiliation (Current) 2025: 生理学研究所, 基盤神経科学研究領域, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 名古屋大学, 環境医学研究所, 特任助教
2012: 京都大学, 大学院・医学研究科, 助教
2011 – 2012: 京都大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 38030:Applied biochemistry-related / Transformative Research Areas, Section (III) / General medical chemistry
Except Principal Investigator
Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Basic Section 42020:Veterinary medical science-related
Keywords
Principal Investigator
冬眠 / 代謝 / 活性酸素 / 低温耐性 / スクリーニング / 細胞死 / 低温 / 比較生物学 / 神経回路 / 体温 … More / 休眠 / 国際情報交流 / アデノシン / 抗炎症 / 生理活性 / アポトーシス / 免疫学 … More
Except Principal Investigator
下行性疼痛抑制経路 / ストレス / 大腸運動 / 脊髄 / 排便 / 消化管 / 下行性疼痛制御経路 / イメージング / 光計測 / 日内休眠 / 体温 / 光操作 / 体温調節 / 睡眠・覚醒 / 代謝 / 休眠 / 視交叉上核 / 視床下部 / 神経回路 / 概日リズム / 下痢 / 下行性疼痛抑制系 / 痛み / 性差 Less
  • Research Projects

    (6 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (13 People)
  •  休眠を制御する神経回路とその作動機構の解明Principal Investigator

    • Principal Investigator
      山口 裕嗣
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Nagoya University
  •  脳と大腸を機能連関させる神経回路のリモデリングとその排便異常への関与

    • Principal Investigator
      志水 泰武
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Gifu University
  •  From Hibernation to Healthcare: Utilizing Cold Tolerance Mechanisms for Medical ApplicationsPrincipal Investigator

    • Principal Investigator
      山口 裕嗣
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38030:Applied biochemistry-related
    • Research Institution
      Nagoya University
  •  Elucidation of the mechanism of thermoregulation by the circadian clock

    • Principal Investigator
      Daisuke Ono
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
    • Research Institution
      Nagoya University
  •  Elucidation of the sex difference in the regulatory mechanism of colonic motility control by the central nervous system and that in defecation disorders.

    • Principal Investigator
      Shimizu Yasutake
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Gifu University
  •  Identification of the factor released from apoptotic cells that regulates the gene expressions in macrophagesPrincipal Investigator

    • Principal Investigator
      YAMAGUCHI Hiroshi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University

All 2024 2023 2022 2021 2011

All Journal Article Presentation

  • [Journal Article] Essential roles of the hypothalamic A11 region and the medullary raphe nuclei in regulation of colorectal motility in rats.2023

    • Author(s)
      Tomoya Sawamura, Natsufu Yuki, Kazuhiro Horii, Kiyotada Naitou, Hiroshi Yamaguchi, Akihiro Yamanaka, Takahiko Shiina, Yasutake Shimizu
    • Journal Title

      American Journal of Physiology-Gastrointestinal and Liver Physiology

      Volume: in press Issue: 6 Pages: G466-G475

    • DOI

      10.1152/ajpgi.00019.2023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03148, KAKENHI-PROJECT-23K18081, KAKENHI-PROJECT-23KJ1047, KAKENHI-PROJECT-23K05553, KAKENHI-PROJECT-23H00360, KAKENHI-PROJECT-23K23788
  • [Journal Article] Dorsomedial and preoptic hypothalamic circuits control torpor2023

    • Author(s)
      Hiroshi Yamaguchi, Keith R. Murphy, Noriaki Fukatsu, Kazuhide Sato, Akihiro Yamanaka, Luis de Lecea
    • Journal Title

      Current Biology

      Volume: 33 Issue: 24 Pages: 5381-5389

    • DOI

      10.1016/j.cub.2023.10.076

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K26830
  • [Journal Article] Functional Interaction Between GABAergic Neurons in the Ventral Tegmental Area and Serotonergic Neurons in the Dorsal Raphe Nucleus2022

    • Author(s)
      Rahaman Sheikh Mizanur、Chowdhury Srikanta、Mukai Yasutaka、Ono Daisuke、Yamaguchi Hiroshi、Yamanaka Akihiro
    • Journal Title

      Frontiers in Neuroscience

      Volume: 16 Pages: 808754-808754

    • DOI

      10.3389/fnins.2022.877054

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-20KK0177, KAKENHI-PROJECT-21H02526, KAKENHI-PROJECT-22KF0166, KAKENHI-PROJECT-21K19255, KAKENHI-PROJECT-21K20688, KAKENHI-PUBLICLY-21H00307, KAKENHI-PUBLICLY-21H00422
  • [Presentation] 排便を制御する下行性セロトニン作動性神経に作用する神経経路の特定2024

    • Author(s)
      湯木夏扶、澤村友哉、堀井和広、山口裕嗣、山中章弘、椎名貴彦、志水泰武
    • Organizer
      第101回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-23H00360
  • [Presentation] 透明脳スクリーニングを用いたマウス日内休眠を制御する神経回路の同定2023

    • Author(s)
      山口裕嗣
    • Organizer
      第101回 日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-23K26830
  • [Presentation] ラットにおける視床下部背内側核のグルタミン酸受容体の活性化は、延髄縫線核およびA11領域から脊髄へ投射する下行性モノアミン作動性神経を介して排便を起こす2023

    • Author(s)
      湯木夏扶、澤村友哉、堀井和広、山口裕嗣、山中章弘、椎名貴彦、志水泰武
    • Organizer
      第166回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-23H00360
  • [Presentation] ラットにおける視床下部背内側核の活性化は延髄縫線核を経由して脊髄排便中枢を活性化することで大腸運動を亢進させる (Activation of the dorsomedial hypothalamus enhances colorectal motility by activating spinal defecation center via themedullary raphe in rats)2023

    • Author(s)
      湯木 夏扶、堀井 和広、澤村 友哉、山口 裕嗣、山中 章弘、椎名 貴彦、志水 泰武
    • Organizer
      第100回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] ラットにおける視床下部背内側核の活性化は下行性モノアミン作動性神経の活性化を介して大腸運動を亢進する2023

    • Author(s)
      湯木夏扶、澤村友哉、堀井和広、山口裕嗣、山中章弘、椎名貴彦、志水泰武
    • Organizer
      第32回日本病態生理学会大会
    • Data Source
      KAKENHI-PROJECT-23H00360
  • [Presentation] Neural pathways of the dorsomedial hypothalamus activation-induced enhancing colorectal motility.2023

    • Author(s)
      Natsufu Yuki, Tomoya Sawamura, Kazuhiro Horii, Hiroshi Yamaguchi, Akihiro Yamanaka, Takahiko Shiina, Yasutake Shimizu
    • Organizer
      The 10th Federation of the Asian and Oceanian Physiological Societies Congress(FAOPS2023)
    • Data Source
      KAKENHI-PROJECT-23H00360
  • [Presentation] 視床下部A11 領域と延髄縫線核は脊髄排便中枢を介して中枢性に大腸運動を制御する (The hypothalamic A11 region and the medullary raphe nuclei regulate colorectal motility mediated through the spinal defecation center)2023

    • Author(s)
      澤村 友哉、堀井 和広、湯木 夏扶、山口 裕嗣、山中 章弘、椎名 貴彦、志水 泰武
    • Organizer
      第100回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] ストレスが排便を誘発する神経経路の検討 -ラットにおける視床下部背内側核の活性化に着目した研究-2023

    • Author(s)
      湯木夏扶、澤村友哉、堀井和広、山口裕嗣、山中章弘、椎名貴彦、志水泰武
    • Organizer
      第65回日本平滑筋学会総会
    • Data Source
      KAKENHI-PROJECT-23H00360
  • [Presentation] Role of Descending Monoaminergic Neurons From The A11 Region And Medullary Raphe Nuclei In Regulation of Colorectal Motility In Rats.2022

    • Author(s)
      Tomoya Sawamura, Kazuhiro Horii, Natsufu Yuki, Kiyotada Naitou, Hiroshi Yamaguchi, Akihiro Yamanaka, Takahiko Shiina, Yasutake Shimizu
    • Organizer
      ISAN (12th Congress of International Society for Autonomic Neuroscience) 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] ラット視床下部背内側核の活性化は、下行性モノアミン作動性神経を介して大腸運動を促進する2022

    • Author(s)
      湯木 夏扶、堀井 和広、澤村 友哉、山口 裕嗣、山中 章弘、椎名 貴彦、志水 泰武
    • Organizer
      第31回日本病態生理学会大会
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] Glutamatergic Stimulation of The Dorsomedial Hypothalamus Enhances Colorectal Motility By Activating Descending Serotonergic And Dopaminergic Neurons In Rats.2022

    • Author(s)
      Natsufu Yuki, Tomoya Sawamura, Kazuhiro Horii, Kiyotada Naitou, Hiroshi Yamaguchi, Akihiro Yamanaka, Takahiko Shiina, Yasutake Shimizu
    • Organizer
      ISAN (12th Congress of International Society for Autonomic Neuroscience) 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] 化学遺伝学的手法を用いた脳から脊髄へ投射する神経の活動操作による大腸運動制御メカニズムの解明2022

    • Author(s)
      澤村 友哉、堀井 和広、湯木 夏扶、山口 裕嗣、山中 章弘、椎名 貴彦、志水 泰武
    • Organizer
      第31回日本病態生理学会大会
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] ラットにおける間脳A11領域および延髄縫線核から脊髄へ投射するモノアミン作動性神経は大腸運動を制御する2022

    • Author(s)
      澤村友哉、堀井和広、湯木夏扶、山口裕嗣、山中章弘、椎名貴彦、志水泰武
    • Organizer
      第69回中部日本生理学会
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] ラットにおける視床下部背内側核の活性化は、脊髄排便中枢でのモノアミン放出を介して大腸運動を促進する2022

    • Author(s)
      湯木夏扶、堀井和広、澤村友哉、山口裕嗣、山中章弘、椎名貴彦、志水泰武
    • Organizer
      第69回中部日本生理学会
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] ラットの視床下部背内側核のグルタミン酸受容体の活性化は大腸運動を亢進する2021

    • Author(s)
      湯木夏扶、堀井和広、澤村友哉、山口裕嗣、山中章弘、椎名貴彦、志水泰武
    • Organizer
      第164回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] ラットにおける大腸運動を調節する脳領域特定のための薬理遺伝学的アプローチ (A chemogenetic approach to identify brain regions regulating colorectal motility in rat)2021

    • Author(s)
      澤村友哉、堀井和広、椎名貴彦、山口裕嗣、山中章弘、志水泰武
    • Organizer
      第98回日本生理学会大会・第126回 日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] ラットのA11 領域ドパミン神経と縫線核セロトニン神経は脊髄排便中枢を介して大腸運動を制御する2021

    • Author(s)
      澤村友哉、堀井和広、湯木夏扶、山口裕嗣、山中章弘、椎名貴彦、志水泰武
    • Organizer
      第68回中部日本生理学会
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] Role of monoaminergic and GABAergic neurons projecting from the raphe nuclei and A11 region to the spinal defecation center in regulation of colorectal motility in rats.2021

    • Author(s)
      澤村友哉、堀井和広、椎名貴彦、山口裕嗣、山中章弘、志水泰武
    • Organizer
      第44回日本神経科学大会/第1回CJK国際会議
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] ラット大腸運動の制御に関与する脳領域の薬理遺伝学的手法による解明2021

    • Author(s)
      澤村友哉、堀井和広、湯木夏扶、山口裕嗣、山中章弘、椎名貴彦、志水泰武
    • Organizer
      第164回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03148
  • [Presentation] Release by apoptotic cells of a factor(s) that regulates the gene expression in macrophages.2011

    • Author(s)
      Hiroshi Yamaguchi, Shigekazu Nagata
    • Organizer
      13th International TNF Conference
    • Place of Presentation
      Awaji Yumebutai International Conference Center, Hyogo, Japan
    • Data Source
      KAKENHI-PROJECT-23790330
  • 1.  Shimizu Yasutake (40243802)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 19 results
  • 2.  内藤 清惟 (30794903)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  Daisuke Ono (30634224)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  山中 章弘 (60323292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 5.  中村 孝博 (00581985)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  伊藤 直人 (20334922)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  土井 謙太郎 (20378798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  宮脇 慎吾 (70756759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  任 書晃 (80644905)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  海野 年弘 (90252121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  椎名 貴彦 (90362178)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  新家 清惟
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 13.  向井 康敬
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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