AKAMA TOMOYA 赤間智也

… Alternative Names

AKAMA Tomoya 赤間智也

Less

Researcher Number	10548788
Other IDs
Affiliation (Current)	2025: 関西医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 関西医科大学, 医学部, 准教授 2013 – 2017: 関西医科大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Ophthalmology Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Basic Section 49020:Human pathology-related
Keywords	Principal Investigator 細胞外マトリックス / 糖鎖 / グリコシターゼ / グリコシダーゼ / 角膜 / グリコサミノグリカン / 糖分解酵素 / 硫酸転移酵素 / 糖転移酵素 / ノックアウトマウス … More / ケラタン硫酸 / 毛様小体 / 毛様小帯 / 水晶体脱臼 / 緑内障 / 疾患モデル動物 / 遺伝病 / 遺伝子改変動物 / ミクロフィブリル / 細胞外マトリックス構築 … More Except Principal Investigator 肺腺癌 / MECA-79 / 再発 / 標的治療 / 糖鎖抗原 / 光免疫療法 / 硫酸化糖鎖 / 卵巣癌 / 癌免疫抑制機構 / 浸潤 / 高内皮細静脈(HEV) / 立体病理 / 立体的病理 / 病期 IA / TLSs / CAFs / HEVs / 3次元解析 / invasive front / fibroblast / high-endothelial venules / 肺癌 / nCounter / 胸腺腫 / 胸腺癌 / PRAME Less

Elucidating mechanism of high-grade malignancy of lung adenocarcinoma focusing on carbohydrate antigen MECA-79
- Principal Investigator
  
  齊藤朋人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kansai Medical University
Novel anti-sulfated glycan antibodies for ovarian cancer pathology diagnosis and photoimmunotherapy
- Principal Investigator
  
  Kobayashi Motohiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  University of Fukui
Preferentially Expressed Antigen in Melanoma in thymic carcinoma: investigation of biological significance and application for novel therapy
- Principal Investigator
  
  TANIGUCHI Yohei
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kansai Medical University
Spatial pathology on invasive front and tertiary lymphoid structure in lung adenocarcinoma
- Principal Investigator
  
  SAITO Tomohito
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kansai Medical University
Alteration of cornea thickness by modifying component of corneal extracellular matrixPrincipal Investigator
- Principal Investigator
  
  AKAMA Tomoya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Kansai Medical University
Biological function of matrix protein LTBP-2 and its involvement in eye diseasesPrincipal Investigator
- Principal Investigator
  
  AKAMA Tomoya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kansai Medical University

All 2024 2023 2022 2021 2018 2017 2016 2014 2013

All Journal Article Presentation

[Journal Article] Establishment of a human ovarian clear cell carcinoma cell line mutant in PIK3CB but not PIK3CA2024
- Author(s)
  Hoshino Hitomi、Inoue Daisuke、Shinagawa Akiko、Yoshida Hisato、Shigeto Shohei、Matsuda Kazuyuki、Akama Tomoya O.、Yoshida Yoshio、Kobayashi Motohiro
- Journal Title
  
  Human Cell
  
  Volume: - Issue: 4 Pages: 1184-1193
- DOI
  10.1007/s13577-024-01058-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02702
[Journal Article] Expression of low-sulfated keratan sulfate in non-mucinous ovarian carcinoma2024
- Author(s)
  Hoshino H, Chen YY, Inoue D, Yoshida Y, Khoo KH, Akama TO, Kobayashi M
- Journal Title
  
  Glycobiology
  
  Volume: 34 Issue: 1
- DOI
  10.1093/glycob/cwad056
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06977, KAKENHI-PROJECT-21H02702
[Journal Article] Structural Elucidation and Prognostic Relevance of 297-11A-Sulfated Glycans in Ovarian Carcinoma2024
- Author(s)
  Inoue Daisuke、Hoshino Hitomi、Chen Ya-Ying、Yamamoto Makoto、Kogami Akiya、Fukushima Mana、Khoo Kay-Hooi、Akama Tomoya O.、Yoshida Yoshio、Kobayashi Motohiro
- Journal Title
  
  Laboratory Investigation
  
  Volume: 104 Issue: 6 Pages: 102057-102057
- DOI
  10.1016/j.labinv.2024.102057
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02702
[Journal Article] Vascular E-selectin expression detected in formalin-fixed, paraffin-embedded sections with an E-selectin monoclonal antibody correlates with ulcerative colitis activity2022
- Author(s)
  Murahashi M, Kogami A, Muramoto A, Hoshino H, Akama TO, Mitoma J, Goi T, Hirayama A, Okamura T, Nagaya T, Kobayashi M
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 70 Issue: 4 Pages: 299-310
- DOI
  10.1369/00221554221085336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02702
[Journal Article] Expression and Clinical Significance of Spi-B in B-cell Acute Lymphoblastic Leukemia2022
- Author(s)
  Yuzuru Ariga, Shulin Low, Hitomi Hoshino, Tsutomu Nakada, Tomoya O Akama, Akifumi Muramoto, Mana Fukushima, Takahiro Yamauchi, Yusei Ohshima, Motohiro Kobayashi
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 70 Issue: 10 Pages: 683-694
- DOI
  10.1369/00221554221130383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06977, KAKENHI-PROJECT-21H02702, KAKENHI-PROJECT-20K16173
[Journal Article] The conspicuousness of high endothelial venues in angioimmunoblastic T-cell lymphoma is due to increased cross-sectional area, not increased distribution density2021
- Author(s)
  Kogami A, Fukushima M, Hoshino H, Komeno T, Okoshi T, Murahashi M, Akama TO, Mitoma J, Ohtani H, Kobayashi M
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 69 Issue: 10 Pages: 645-657
- DOI
  10.1369/00221554211048551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02702, KAKENHI-PROJECT-20K16173
[Journal Article] Apical membrane expression of distinct sulfated glycans is a characteristic feature of ductules and their reactive and neoplastic counterparts2021
- Author(s)
  Hoshino H, Akama TO, Uchimura K, Fukushima M, Muramoto A, Uehara T, Nakanuma Y, Kobayashi M
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 69 Issue: 9 Pages: 555-573
- DOI
  10.1369/00221554211035730
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02702, KAKENHI-PROJECT-20K16173
[Journal Article] Keratan Sulfate Phenotype in the β-1,3-N-Acetylglucosaminyltransferase-7?Null Mouse Cornea2018
- Author(s)
  Littlechild Stacy L.、Young Robert D.、Caterson Bruce、Yoshida Hideyuki、Yamazaki Maya、Sakimura Kenji、Quantock Andrew J.、Akama Tomoya O.
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 59 Issue: 3 Pages: 1641-1641
- DOI
  10.1167/iovs.17-22716
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19444, KAKENHI-PROJECT-16K15739, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25000015
[Journal Article] Latent TGF-β binding protein 2 and 4 have essential overlapping functions in microfibril development.2017
- Author(s)
  Fujikawa Y, Yoshida H, Inoue T, Ohbayashi T, Noda K, von Melchner H, Iwasaka T, Shiojima I, Akama TO, Nakamura T
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 43714-43714
- DOI
  10.1038/srep43714
- NAID
  120006358789
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05145, KAKENHI-PROJECT-16K15739, KAKENHI-PROJECT-16K15749
[Journal Article] Latent TGFβ binding protein-2 is essential for the development of ciliary zonule microfibrils.2014
- Author(s)
  Inoue T., Ohbayashi T., Fujikawa Y., Yoshida H., Akama T.O., Noda K., Horiguchi M., Kameyama K., Hata Y., Takahashi K., Kusumoto K. and Nakamura T.
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 23 Issue: 21 Pages: 5672-5682
- DOI
  10.1093/hmg/ddu283
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22115010, KAKENHI-PROJECT-24592724, KAKENHI-PROJECT-25462741, KAKENHI-PROJECT-26670147
[Journal Article] Latent TGF-beta binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5.2013
- Author(s)
  Noda K., Dabovic B., Takagi K., Inoue T., Horiguchi M., Hirai M., Fujikawa Y., Akama T. O., Kusumoto K., Zilberberg L., Sakai L. Y., Koli K., Naitoh M., von Melchner H., Suzuki S., Rifkin D. B., Nakamura T
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 110 Issue: 8 Pages: 2852-2857
- DOI
  10.1073/pnas.1215779110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249078, KAKENHI-PROJECT-25462741
[Presentation] 低硫酸化ケラタン硫酸を発現する明細胞卵巣癌細胞株の樹立2024
- Author(s)
  星野　瞳，井上大輔，吉田寿人，重藤翔平，松田和之，赤間智也，吉田好雄，小林基弘
- Organizer
  第113回日本病理学会総会，下関
- Data Source
  KAKENHI-PROJECT-21H02702
[Presentation] Structural elucidation and prognostic relevance of 297-11A-sulfated glycans in ovarian carcinoma2024
- Author(s)
  Inoue D, Hoshino H, Chen YY, Yamamoto M, Kogami A, Fukushima M, Khoo KH, Akama TO, Yoshida Y, Kobayashi M
- Organizer
  26th Annual San Diego Glycobiology Symposium, San Diego, CA, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02702
[Presentation] Expression of low-sulfated keratan sulfate in non-mucinous ovarian carcinoma2023
- Author(s)
  Hoshino H, Chen YY, Inoue D, Yoshida Y, Khoo KH, Akama TO, Kobayashi M
- Organizer
  International Symposium on Glycoconjugates, Taipei, Taiwan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02702
[Presentation] 血管芽球性T細胞リンパ腫では、なぜ高内皮細静脈が目立つのか2022
- Author(s)
  小上瑛也，福島万奈，星野　瞳，米野琢哉，大越忠和，村橋将崇，赤間智也，三苫純也，大谷明夫，小林基弘
- Organizer
  第111回日本病理学会総会，神戸
- Data Source
  KAKENHI-PROJECT-21H02702
[Presentation] ヒト卵巣癌由来細胞株の樹立2022
- Author(s)
  星野　瞳，井上大輔，赤間智也，吉田好雄，小林基弘
- Organizer
  第68回日本病理学会秋期特別総会，盛岡
- Data Source
  KAKENHI-PROJECT-21H02702
[Presentation] 297-11A抗体のゴルジ陽性パターンはコンドロイチン6硫酸転移酵素の機能を反映する2022
- Author(s)
  福島万奈，星野　瞳，山中麻衣子，加藤久隆，赤間智也，小林基弘
- Organizer
  第111回日本病理学会総会，神戸
- Data Source
  KAKENHI-PROJECT-21H02702
[Presentation] Determination fo the minimum enzymatic domain of keratanase II2017
- Author(s)
  Tomoya O. Akama, Toshisuke Kawasaki, Tomoyuki Nakamura
- Organizer
  Society for Glycobiology 2017 Annual Meeting
- Data Source
  KAKENHI-PROJECT-16K15739
[Presentation] KeratanaseIIの最小酵素活性ドメインの同定2017
- Author(s)
  赤間智也、川嵜敏祐、中邨智之
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-16K15739
[Presentation] B. fragilis endo-beta-galactosidaseのクローニングとその酵素活性解析2016
- Author(s)
  赤間智也、安形清彦、久保田智巳、中邨智之、福田道子
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K15739
[Presentation] Mutant LTBP-2 proteins lack secretion ability and fibrillin-1 binding ability.2013
- Author(s)
  Akama, T.O., Fujikawa, Y., Inoue, T., Nakamura, T.
- Organizer
  Annual meeting of Association for Research in Vision and Ophthalmology
- Place of Presentation
  Seattle, WA, USA
- Data Source
  KAKENHI-PROJECT-25462741

1. SAITO Tomohito (10548605)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 石田光明 (00464173)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 林美樹夫 (10368251)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TANIGUCHI Yohei (50609592)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 蔦幸治 (00392332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 村川知弘 (50359626)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. Kobayashi Motohiro (00362137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
8. 長屋匡信 (00718033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 坂本毅治 (70511418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAITOH Motoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 中邨智之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 鈴木茂彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 崎村建司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 星野瞳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 畠義郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AKAMA TOMOYA 赤間 智也

AKAMA Tomoya 赤間 智也

Research Projects

Research Products

Co-Researchers

Elucidating mechanism of high-grade malignancy of lung adenocarcinoma focusing on carbohydrate antigen MECA-79

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel anti-sulfated glycan antibodies for ovarian cancer pathology diagnosis and photoimmunotherapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preferentially Expressed Antigen in Melanoma in thymic carcinoma: investigation of biological significance and application for novel therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Spatial pathology on invasive front and tertiary lymphoid structure in lung adenocarcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Alteration of cornea thickness by modifying component of corneal extracellular matrixPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biological function of matrix protein LTBP-2 and its involvement in eye diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Establishment of a human ovarian clear cell carcinoma cell line mutant in PIK3CB but not PIK3CA2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of low-sulfated keratan sulfate in non-mucinous ovarian carcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural Elucidation and Prognostic Relevance of 297-11A-Sulfated Glycans in Ovarian Carcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vascular E-selectin expression detected in formalin-fixed, paraffin-embedded sections with an E-selectin monoclonal antibody correlates with ulcerative colitis activity2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression and Clinical Significance of Spi-B in B-cell Acute Lymphoblastic Leukemia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The conspicuousness of high endothelial venues in angioimmunoblastic T-cell lymphoma is due to increased cross-sectional area, not increased distribution density2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Apical membrane expression of distinct sulfated glycans is a characteristic feature of ductules and their reactive and neoplastic counterparts2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Keratan Sulfate Phenotype in the β-1,3-N-Acetylglucosaminyltransferase-7?Null Mouse Cornea2018

Author(s)

Journal Title

DOI

AKAMA TOMOYA 赤間智也

AKAMA Tomoya 赤間智也