Ogura Masato 小椋正人

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OGURA MASATO 小椋正人

OGURA Masato 小椋正人

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Researcher Number	10548978
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2018 – 2023: 福島県立医科大学, 医学部, 講師 2015 – 2016: 福島県立医科大学, 医学部, 助教 2011 – 2012: 福島県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / General pharmacology / General medical chemistry
Keywords	Principal Investigator 活性酸素種 / ミトコンドリア / プロテオーム / シグナル伝達 / 質量分析 / 神経変性疾患 / アポトーシス / 神経細胞死 / PAK2 / アストロサイト … More / 細胞死 / 分泌因子 / 低分子化合物 / アストログリア細胞 / 神経細胞 / 複合体 / 電子伝達系 / エネルギー代謝 / チロシンキナーゼ Less

Functional analysis of PAK2 in reactive astrocytesPrincipal Investigator
- Principal Investigator
  
  Ogura Masato
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Fukushima Medical University
Elucidation of the mechanism of substantia nigra astroglial cell activation by metabolic reactive oxygen species and identification of its regulatorPrincipal Investigator
- Principal Investigator
  
  Ogura Masato
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Fukushima Medical University
Creation of neurodegenerative model due to mitochondrial reactive oxygen species and identification of novel disease moleculesPrincipal Investigator
- Principal Investigator
  
  OGURA MASATO
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Fukushima Medical University
Identification and functional analysis of novel interacting proteins for regulation of mitochondrial c-Src activityPrincipal Investigator
- Principal Investigator
  
  OGURA Masato
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Fukushima Medical University

All 2023 2022 2021 2020 2019 2017 2016 2013 2012 2011 Other

All Journal Article Presentation Patent

[Journal Article] Prenylated quinolinecarboxylic acid compound-18 prevents sensory nerve fiber outgrowth through inhibition of the interleukin-31 pathway2021
- Author(s)
  Ogura Masato、Endo Kumiko、Suzuki Toshiyuki、Homma Yoshimi
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 2 Pages: e0246630-e0246630
- DOI
  10.1371/journal.pone.0246630
- NAID
  130008001229
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06702
[Journal Article] Astrocyte-Derived Exosomal microRNA miR-200a-3p Prevents MPP +-Induced Apoptotic Cell Death Through Down-Regulation of MKK42020
- Author(s)
  Norshalena Shakespear, Masato Ogura, Junko Yamaki, Yoshimi Homma
- Journal Title
  
  Neurochem Res.
  
  Volume: 45 Issue: 5 Pages: 1020-1033
- DOI
  10.1007/s11064-020-02977-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06702
[Journal Article] Prenylated quinolinecarboxylic acid derivative prevents neuronal cell death through inhibition of MKK42019
- Author(s)
  Ogura Masato、Kikuchi Haruhisa、Shakespear Norshalena、Suzuki Toshiyuki、Yamaki Junko、Homma Miwako K.、Oshima Yoshiteru、Homma Yoshimi
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 162 Pages: 109-122
- DOI
  10.1016/j.bcp.2018.10.008
- NAID
  120006821695
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06702, KAKENHI-PROJECT-16H03279
[Journal Article] Mitochondrial reactive oxygen species suppress humoral immune response through reduction of CD19 expression in B cells in mice2017
- Author(s)
  Masato Ogura, Takeshi Inoue, Junko Yamaki, Miwako K. Homma, Tomohiro Kurosaki, Yoshimi Homma
- Journal Title
  
  Eur J Immunol
  
  Volume: 47 Issue: 2 Pages: 406-418
- DOI
  10.1002/eji.201646342
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460372, KAKENHI-PROJECT-15K19127, KAKENHI-PROJECT-15K21261
[Journal Article] Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components2012
- Author(s)
  Ogura M, Yamaki J, Homma MK, Homma Y
- Journal Title
  
  Biochem J
  
  Volume: 447 Issue: 2 Pages: 281-289
- DOI
  10.1042/bj20120509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790341
[Patent] 体重増加制御剤2012
- Inventor(s)
  大島吉輝、菊池晴久、本間好、鈴木俊幸、小椋正人
- Industrial Property Rights Holder
  国立大学法人東北大学、公立大学法人福島県立医科大学
- Filing Date
  2012-10-18
- Data Source
  KAKENHI-PROJECT-23790341
[Presentation] ミトコンドリア活性酸素種による神経傷害性アストログリア活性化機構の解明2023
- Author(s)
  小椋　正人、八巻　淳子、本間　美和子
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06598
[Presentation] Elucidation of the mechanism of substantia nigra astroglial cell activation by metabolic reactive oxygen species2022
- Author(s)
  Masato Ogura and Ikuo Wada
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06598
[Presentation] Glial-derived secreted protein Tinagl1 regulates neuronal survival2022
- Author(s)
  Masato Ogura, Seya Onotsuka, Junko Yamaki, Ikuo Wada and Miwako K. Homma
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06598
[Presentation] プレニルキノリンカルボン酸誘導体-18は、インターロイキン31経路の阻害を通して知覚神経線維の成長を抑制する2021
- Author(s)
  Masato Ogura, Kumiko Endo, Toshiyuki Suzuki and Yoshimi Homma
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06702
[Presentation] Prenylated quinolinecarboxylic acid derivative prevents neuronal cell death through inhibition of MKK42019
- Author(s)
  Ogura Masato、Kikuchi Haruhisa、Shakespear Norshalena、Suzuki Toshiyuki、Yamaki Junko、Homma Miwako K.、Oshima Yoshiteru、Homma Yoshimi
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06702
[Presentation] Phosphorylation of respiratory chain components by mitochondrial c-Src is required for neuronal viability2016
- Author(s)
  Masato Ogura, Junko Yamaki, Miwako K. Homma, and Yoshimi Homma
- Organizer
  Neuroscience2016
- Place of Presentation
  San Diego
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21261
[Presentation] Phosphorylation of respiratory complex I and II by c-Src is required for neuronal viability2013
- Author(s)
  Ogura M, Yamaki J, Homma MK, Kato S,Kobayashi K, Kobayashi K, Homma Y
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23790341
[Presentation] Identification and functional analysis of novel interaction proteins for regulation of reactive oxygen species generation in succinate dehydrogenase2012
- Author(s)
  Ogura M, Yamaki J, Homma MK, Homma Y
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23790341
[Presentation] Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components2012
- Author(s)
  Ogura M, Yamaki J, Homma MK, Homma Y
- Organizer
  第55回日本神経化学会大会
- Place of Presentation
  神戸
- Year and Date
  2012-10-01
- Data Source
  KAKENHI-PROJECT-23790341
[Presentation] 呼吸機能におけるミトコンドリア内c-Srcの役割2011
- Author(s)
  小椋正人、八巻淳子、本間美和子、本間好
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-23790341
[Presentation] ミトコンドリアc-Srcキナーゼ活性を制御する新規相互作用タンパク質の同定と機能解析2011
- Author(s)
  小椋正人、八巻淳子、本間美和子、本間好
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23790341
[Presentation] ミトコンドリアc-Srcによる細胞死制御メカニズム2011
- Author(s)
  小椋正人、八巻淳子、本間美和子、本間好
- Organizer
  日本生化学会東北支部第77回例会・シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-23790341
[Presentation] Phosphorylation of respiratory complex I and II by c-Src is required for neuronal viability
- Author(s)
  Ogura M, Yamaki J, Homma MK, Kato S, Kobayashi K, Kobayashi K, Homma Y
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790341

1. 本間好

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogura Masato 小椋 正人

OGURA MASATO 小椋 正人

OGURA Masato 小椋 正人

Research Projects

Research Products

Co-Researchers

Functional analysis of PAK2 in reactive astrocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of substantia nigra astroglial cell activation by metabolic reactive oxygen species and identification of its regulatorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Creation of neurodegenerative model due to mitochondrial reactive oxygen species and identification of novel disease moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and functional analysis of novel interacting proteins for regulation of mitochondrial c-Src activityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Prenylated quinolinecarboxylic acid compound-18 prevents sensory nerve fiber outgrowth through inhibition of the interleukin-31 pathway2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Astrocyte-Derived Exosomal microRNA miR-200a-3p Prevents MPP +-Induced Apoptotic Cell Death Through Down-Regulation of MKK42020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prenylated quinolinecarboxylic acid derivative prevents neuronal cell death through inhibition of MKK42019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Mitochondrial reactive oxygen species suppress humoral immune response through reduction of CD19 expression in B cells in mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components2012

Author(s)

Journal Title

DOI

Data Source

[Patent] 体重増加制御剤2012

Inventor(s)

Industrial Property Rights Holder

Filing Date

Data Source

[Presentation] ミトコンドリア活性酸素種による神経傷害性アストログリア活性化機構の解明2023

Author(s)

Organizer

Data Source

[Presentation] Elucidation of the mechanism of substantia nigra astroglial cell activation by metabolic reactive oxygen species2022

Author(s)

Organizer

Data Source

[Presentation] Glial-derived secreted protein Tinagl1 regulates neuronal survival2022

Author(s)

Organizer

Data Source

[Presentation] プレニルキノリンカルボン酸誘導体-18は、インターロイキン31経路の阻害を通して知覚神経線維の成長を抑制する2021

Author(s)

Organizer

Data Source

[Presentation] Prenylated quinolinecarboxylic acid derivative prevents neuronal cell death through inhibition of MKK42019

Author(s)

Ogura Masato 小椋正人

OGURA MASATO 小椋正人

OGURA Masato 小椋正人