Toriumi Kazuya 鳥海和也

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TORIUMI Kazuya 鳥海和也

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Researcher Number	10549421
Other IDs
Affiliation (Current)	2025: 公益財団法人東京都医学総合研究所, 臨床医科学研究分野, 副参事研究員 2025: 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 主席研究員
Affiliation (based on the past Project Information) *help	2022 – 2025: 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 主席研究員 2017 – 2021: 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 主任研究員 2014 – 2016: 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 研究員 2012: 東京都医学総合研究所, 固有研究員
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Basic Section 49010:Pathological biochemistry-related / Neurochemistry/Neuropharmacology Except Principal Investigator Medium-sized Section 58:Society medicine, nursing, and related fields / Psychiatric science
Keywords	Principal Investigator 統合失調症 / ペントシジン / グルクロン酸 / WGCNA / Glo1 / 前頭皮質 / 酸化ストレス / ミトコンドリア / ビタミンB6 / GLO1 … More / メチルグリオキサール / カルボニルストレス / ストレス / 海馬 / 神経新生 / 抗精神病薬 / テロメア … More Except Principal Investigator コホート / 予防 / 老化 / 若者 / アセチルトランスフェラーゼ / 側坐核 / N-アセチルアスパラギン酸 / メタンフェタミン / ドパミン / shati / 精神神経疾患 / Shati / プロテオミクス / 薬物依存 / 遺伝子 / 精神薬理学 Less

AGEs蓄積による精神疾患の早期老化病態：疫学研究を起点とする分子基盤の解明Principal Investigator
- Principal Investigator
  
  鳥海和也
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
若者の老化ペースを速める胎内から思春期までの要因とその予防戦略に関する研究
- Principal Investigator
  
  西田淳志
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Elucidation of the molecular pathogenesis of schizophrenia based on a novel pentosidine-producing pathwayPrincipal Investigator
- Principal Investigator
  
  鳥海和也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Study on mechanism underlying schizophrenia development by carbonyl stressPrincipal Investigator
- Principal Investigator
  
  TORIUMI Kazuya
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Study on molecular mechanism for telomere shortening induced by stress exposure on schizophreniaPrincipal Investigator
- Principal Investigator
  
  TORIUMI Kazuya
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Aimed at clinical application, functional analysis of a novelmolecule "SHATI" by proteomics-like technique.
- Principal Investigator
  
  NABESHIMA Toshitaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Meijo University

[Journal Article] Association of homocysteine with white matter dysconnectivity in schizophrenia2024
- Author(s)
  Tabata Koichi、Son Shuraku、Miyata Jun、Toriumi Kazuya、Miyashita Mitsuhiro、Suzuki Kazuhiro、Itokawa Masanari、Takahashi Hidehiko、Murai Toshiya、Arai Makoto
- Journal Title
  
  Schizophrenia
  
  Volume: 10 Issue: 1 Pages: 39-39
- DOI
  10.1038/s41537-024-00458-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07609, KAKENHI-PROJECT-19K17061, KAKENHI-ORGANIZER-23H04972, KAKENHI-PLANNED-23H04979, KAKENHI-PROJECT-23K21413
[Journal Article] Urinary exosomal microRNAs as predictive biomarkers for persistent psychotic-like experiences2023
- Author(s)
  Tomita Y, Suzuki K, Yamasaki S, Toriumi K, Miyashita M, Ando S, Endo K, Yoshikawa A, Tabata K, Usami S, Hiraiwa-Hasegawa M, Itokawa M, Kawaji H, Kasai K, Nishida A, Arai M.
- Journal Title
  
  Schizophrenia
  
  Volume: 9 Issue: 1 Pages: 14-14
- DOI
  10.1038/s41537-023-00340-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07609, KAKENHI-PROJECT-20H01777, KAKENHI-PROJECT-20H03608, KAKENHI-PROJECT-19K17075, KAKENHI-PROJECT-20H03951
[Journal Article] Glucuronic acid is a novel source of pentosidine, associated with schizophrenia2023
- Author(s)
  Toriumi Kazuya、Iino Kyoka、Ozawa Azuna、Miyashita Mitsuhiro、Yamasaki Syudo、Suzuki Kazuhiro、Sugawa Hikari、Tabata Koichi、Yamaguchi Satoshi、Usami Satoshi、Itokawa Masanari、Nishida Atsushi、Nagai Ryoji、Kamiguchi Hidenori、Arai Makoto
- Journal Title
  
  Redox Biology
  
  Volume: 67 Pages: 102876-102876
- DOI
  10.1016/j.redox.2023.102876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07609
[Journal Article] Association between enhanced carbonyl stress and decreased apparent axonal density in schizophrenia by multimodal white matter imaging2023
- Author(s)
  Son Shuraku、Arai Makoto、Toriumi Kazuya、Andica Christina、Matsuyoshi Daisuke、Kamagata Koji、Aoki Shigeki、Kawashima Takahiko、Kochiyama Takanori、Okada Tomohisa、Fushimi Yasutaka、Nakamoto Yuji、Kobayashi Yuko、Murai Toshiya、Itokawa Masanari、Miyata Jun
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 12220-12220
- DOI
  10.1038/s41598-023-39379-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07609, KAKENHI-PROJECT-22K07746, KAKENHI-PROJECT-19K17061, KAKENHI-PROJECT-19H04433, KAKENHI-PROJECT-23K21413
[Journal Article] Hair zinc levels and psychosis risk among adolescents2022
- Author(s)
  Tabata Koichi、Miyashita Mitsuhiro、Yamasaki Syudo、Toriumi Kazuya、Ando Shuntaro、Suzuki Kazuhiro、Endo Kaori、Morimoto Yuko、Tomita Yasufumi、Yamaguchi Satoshi、Usami Satoshi、Itokawa Masanari、Hiraiwa-Hasegawa Mariko、Takahashi Hidehiko、Kasai Kiyoto、Nishida Atsushi、Arai Makoto
- Journal Title
  
  Schizophrenia
  
  Volume: 8 Issue: 1 Pages: 107-107
- DOI
  10.1038/s41537-022-00307-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K03046, KAKENHI-PROJECT-22K07609, KAKENHI-PROJECT-20H01777, KAKENHI-PROJECT-20H03608
[Journal Article] Exonic deletions in IMMP2L in schizophrenia with enhanced glycation stress subtype.2022
- Author(s)
  Yoshikawa A, Kushima I, Miyashita M, Suzuki K, Iino K, Toriumi K, Horiuchi Y, Kawaji H, Ozaki N, Itokawa M, Arai M.
- Journal Title
  
  PLoS One
  
  Volume: 17 Issue: 7 Pages: e0270506-e0270506
- DOI
  10.1371/journal.pone.0270506
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07609, KAKENHI-PROJECT-20H03608
[Journal Article] Role of glyoxalase 1 in methylglyoxal detoxification?the broad player of psychiatric disorders2022
- Author(s)
  Toriumi Kazuya、Miyashita Mitsuhiro、Suzuki Kazuhiro、Tabata Koichi、Horiuchi Yasue、Ishida Hiroaki、Itokawa Masanari、Arai Makoto
- Journal Title
  
  Redox Biology
  
  Volume: 49 Pages: 102222-102222
- DOI
  10.1016/j.redox.2021.102222
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06977
[Journal Article] Cross-disorder analysis of genetic and regulatory copy number variations in bipolar disorder, schizophrenia, and autism spectrum disorder2022
- Author(s)
  Kushima Itaru、Nakatochi Masahiro、Aleksic Branko、Okada Takashi、（中略）、Ozaki Norio
- Journal Title
  
  Biological Psychiatry
  
  Volume: - Issue: 5 Pages: 362-374
- DOI
  10.1016/j.biopsych.2022.04.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07917, KAKENHI-PROJECT-19K08044, KAKENHI-PROJECT-20K07945, KAKENHI-PROJECT-21K07496, KAKENHI-PROJECT-21K07498, KAKENHI-PROJECT-21K07543, KAKENHI-PROJECT-22K07369, KAKENHI-PROJECT-22K07554, KAKENHI-PROJECT-22K07595, KAKENHI-PROJECT-22K07609, KAKENHI-PROJECT-22K07614, KAKENHI-PROJECT-20K20602, KAKENHI-PROJECT-21K18554, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03597, KAKENHI-PROJECT-20H03598, KAKENHI-PROJECT-20H03608, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-19K07384, KAKENHI-PROJECT-19K08251, KAKENHI-PROJECT-19K17059, KAKENHI-PROJECT-21H02848, KAKENHI-PUBLICLY-21H00180, KAKENHI-PUBLICLY-21H00194, KAKENHI-PROJECT-19K17061, KAKENHI-PUBLICLY-21H05326, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K22257
[Journal Article] Advanced glycation end products and cognitive impairment in schizophrenia2021
- Author(s)
  Kobori Akiko、Miyashita Mitsuhiro、Miyano Yasuhiro、Suzuki Kazuhiro、Toriumi Kazuya、Niizato Kazuhiro、Oshima Kenichi、Imai Atsushi、Nagase Yukihiro、Yoshikawa Akane、Horiuchi Yasue、Yamasaki Syudo、Nishida Atsushi、Usami Satoshi、Takizawa Shunya、Itokawa Masanari、Arai Heii、Arai Makoto
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 5 Pages: e0251283-e0251283
- DOI
  10.1371/journal.pone.0251283
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-18K07579, KAKENHI-PROJECT-19H03589, KAKENHI-PROJECT-20H03608
[Journal Article] Dysregulation of post-transcriptional modification by copy number variable microRNAs in schizophrenia with enhanced glycation stress2021
- Author(s)
  Yoshikawa Akane、Kushima Itaru、Miyashita Mitsuhiro、Toriumi Kazuya、Suzuki Kazuhiro、Horiuchi Yasue、Kawaji Hideya、Takizawa Shunya、Ozaki Norio、Itokawa Masanari、Arai Makoto
- Journal Title
  
  Translational Psychiatry
  
  Volume: 11 Issue: 1 Pages: 331-331
- DOI
  10.1038/s41398-021-01460-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06977
[Journal Article] Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment2021
- Author(s)
  Toriumi Kazuya、Miyashita Mitsuhiro、Suzuki Kazuhiro、Yamasaki Nao、Yasumura Misako、Horiuchi Yasue、Yoshikawa Akane、Asakura Mai、Usui Noriyoshi、Itokawa Masanari、Arai Makoto
- Journal Title
  
  Translational Psychiatry
  
  Volume: 11 Issue: 1 Pages: 262-262
- DOI
  10.1038/s41398-021-01381-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04887, KAKENHI-PROJECT-18K15354, KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-19H03589, KAKENHI-PROJECT-20H03608, KAKENHI-PROJECT-20K06872
[Journal Article] Evolution of DNA Methylation in the Human Brain.2021
- Author(s)
  Jeong H, Mendizabal I, Berto S, Chatterjee P, Layman T, Usui N, Toriumi K, Douglas C, Singh D, Huh I, Preuss T, Konopka G, Soojin VYI.
- Journal Title
  
  Nat Commun
  
  Volume: 12 Issue: 1 Pages: 2021-2021
- DOI
  10.1038/s41467-021-21917-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-20K06872
[Journal Article] Accumulation of Carbonyl Proteins in the Brain of Mouse Model for Methylglyoxal Detoxification Deficits2021
- Author(s)
  Koike Shin、Toriumi Kazuya、Kasahara Sakura、Kibune Yosuke、Ishida Yo-ichi、Dan Takashi、Miyata Toshio、Arai Makoto、Ogasawara Yuki
- Journal Title
  
  Antioxidants
  
  Volume: 10 Issue: 4 Pages: 574-574
- DOI
  10.3390/antiox10040574
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04887, KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-19K07208, KAKENHI-PROJECT-21K06652
[Journal Article] AKR1A1 Variant Associated With Schizophrenia Causes Exon Skipping, Leading to Loss of Enzymatic Activity2021
- Author(s)
  Iino Kyoka, Toriumi Kazuya (2番目/23人中), et al.
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 12 Pages: 762999-762999
- DOI
  10.3389/fgene.2021.762999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-19K07851, KAKENHI-PROJECT-19H03579, KAKENHI-PROJECT-19H03589, KAKENHI-PROJECT-20H03608, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-20KK0193
[Journal Article] High-sucrose diets contribute to brain angiopathy with impaired glucose uptake and psychosis-related higher brain dysfunctions in mice2021
- Author(s)
  Hirai Shinobu, Toriumi Kazuya (4番目/24人中), et al.
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 46 Pages: 1-5
- DOI
  10.1126/sciadv.abl6077
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-19K08033, KAKENHI-PROJECT-18K19383, KAKENHI-PROJECT-18K14832, KAKENHI-PROJECT-18H02542, KAKENHI-PUBLICLY-21H00180, KAKENHI-PUBLICLY-21H05694, KAKENHI-PROJECT-19H03589, KAKENHI-PROJECT-20H03608, KAKENHI-PROJECT-18K06496, KAKENHI-PROJECT-21K06403, KAKENHI-PROJECT-20K20392, KAKENHI-PROJECT-18KK0442, KAKENHI-PROJECT-18H02537, KAKENHI-PROJECT-23K21414
[Journal Article] Fingertip advanced glycation end products and psychotic symptoms among adolescents2021
- Author(s)
  Miyashita Mitsuhiro, Toriumi Kazuya (5番目/23人中), et al.
- Journal Title
  
  npj Schizophrenia
  
  Volume: 7 Issue: 1 Pages: 37-37
- DOI
  10.1038/s41537-021-00167-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-18K07579, KAKENHI-INTERNATIONAL-16K21720, KAKENHI-PLANNED-16H06398, KAKENHI-PROJECT-20H01777, KAKENHI-PROJECT-20H03608, KAKENHI-PROJECT-20H03951
[Journal Article] Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia.2021
- Author(s)
  Ohnishi T, Kiyama Y, Arima-Yoshida F, Kadota M, Ichikawa T, Yamada K, Watanabe A, Ohba H, Tanaka K, Nakaya A, Horiuchi Y, Iwayama Y, Toyoshima M, Ogawa I, Shimamoto-Mitsuyama C, Maekawa M, Balan S, Arai M, Miyashita M, Toriumi K, et al.
- Journal Title
  
  EMBO Mol Med
  
  Volume: 13 Issue: 4
- DOI
  10.15252/emmm.202012574
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-19K07799, KAKENHI-PROJECT-19K08023, KAKENHI-PROJECT-20K07934, KAKENHI-PUBLICLY-19H04876, KAKENHI-PUBLICLY-19H04887, KAKENHI-PROJECT-19H03328, KAKENHI-PROJECT-19H03589, KAKENHI-PROJECT-19H03321, KAKENHI-PROJECT-19K06629, KAKENHI-PROJECT-18H03579, KAKENHI-PROJECT-18K07578
[Journal Article] Enhanced Carbonyl Stress and Disrupted White Matter Integrity in Schizophrenia.2020
- Author(s)
  Son S, Arai M, Toriumi K, Mizuta H, Miyata J, Hayashi T, Aso T, Itokawa M, Murai T.
- Journal Title
  
  Schizophr Res
  
  Volume: 223 Pages: 242-248
- DOI
  10.1016/j.schres.2020.08.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06977, KAKENHI-PUBLICLY-19H04887, KAKENHI-PUBLICLY-20H05064, KAKENHI-PROJECT-17H04248, KAKENHI-PROJECT-18H02749, KAKENHI-PROJECT-19H03589, KAKENHI-PROJECT-20H03608, KAKENHI-PROJECT-19K17061
[Journal Article] Cell type-specific epigenetic links to schizophrenia risk in the brain2019
- Author(s)
  Mendizabal Isabel*、Berto Stefano*、Usui Noriyoshi*、Toriumi Kazuya*、Chatterjee Paramita、Douglas Connor、Huh Iksoo、Jeong Hyeonsoo、Layman Thomas、Tamminga Carol A.、Preuss Todd M.、Konopka Genevieve、Yi Soojin V.
- Journal Title
  
  Genome Biology
  
  Volume: 20 Issue: 1 Pages: 135-135
- DOI
  10.1186/s13059-019-1747-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-18K14814
[Journal Article] Accelerated evolution of oligodendrocytes in the human brain2019
- Author(s)
  Berto Stefano*、Mendizabal Isabel*、Usui Noriyoshi*、Toriumi Kazuya*、Chatterjee Paramita、Douglas Connor、Tamminga Carol A.、Preuss Todd M.、Yi Soojin V.、Konopka Genevieve [*Co-first authors]
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 48 Pages: 24334-24342
- DOI
  10.1073/pnas.1907982116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-18K14814
[Journal Article] Protein kinase C δ gene depletion protects against methamphetamine-induced impairments in recognition memory and ERK1/2 signaling via up-regulation of glutathione peroxidase-1 gene.2018
- Author(s)
  Tran TV, Shin EJ, Nguyen LTL, Lee Y, Kim DJ, Jeong JH, Jang CG, Nah SY, Toriumi K, Nabeshima T, Yamada K, Kim HC.
- Journal Title
  
  Mol Neurobiol
  
  Volume: 印刷中 Pages: 4136-4159
- DOI
  10.1007/s12035-017-0638-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878, KAKENHI-PROJECT-18K06977
[Journal Article] Pyridoxamine, A Novel Treatment For Schizophrenia With Enhanced Carbonyl Stress.2018
- Author(s)
  Itokawa M, Miyashita M, Arai M, Dan T, Takahashi K, Tokunaga T, Ishimoto K, Toriumi K, Ichikawa T, Horiuchi Y, Kobori A, Usami S, Yoshikawa T, Amano N, Washizuka S, Okazaki Y, Miyata T.
- Journal Title
  
  Psychiatry Clin Neurosci.
  
  Volume: 72(1) Issue: 1 Pages: 35-44
- DOI
  10.1111/pcn.12613
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05380, KAKENHI-PROJECT-26870878, KAKENHI-PROJECT-18K06977
[Journal Article] Shati/Nat8l knockout mice show behavioral deficits ameliorated by atomoxetine and methylphenidate2018
- Author(s)
  Toriumi Kazuya、Tanaka Junko、Mamiya Takayoshi、Alkam Tursun、Kim Hyoung-Chun、Nitta Atsumi、Nabeshima Toshitaka
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 339 Pages: 207-214
- DOI
  10.1016/j.bbr.2017.11.040
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19801, KAKENHI-PROJECT-15H04662, KAKENHI-PROJECT-26870878, KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-15K08218
[Journal Article] Foxp1 in forebrain pyramidal neurons controls gene expression required for spatial learning and synaptic plasticity.2017
- Author(s)
  Araujo DJ, Toriumi K, Escamilla C, Kulkarni A, Anderson A, Harper M, Usui N, Ellegood J, Lerch J, Birnbaum S, Tucker H, Powell C, Konopka G.
- Journal Title
  
  J Neurosci
  
  Volume: 2017 Issue: 45 Pages: 10917-10931
- DOI
  10.1523/jneurosci.1005-17.2017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Journal Article] Foxp1 regulation of neonatal vocalizations via cortical development.2017
- Author(s)
  Usui N, Araujo DJ, Kulkarni A, Co M, Ellegood J, Harper M, Toriumi K, Lerch JP, Konopka G.
- Journal Title
  
  Genes Dev
  
  Volume: 31 Issue: 20 Pages: 2039-2055
- DOI
  10.1101/gad.305037.117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Journal Article] The regulation of soluble receptor for AGEs contributes to carbonyl stress in schizophrenia.2016
- Author(s)
  Miyashita M, Watanabe T, Ichikawa T, Toriumi K, Horiuchi Y, Kobori A, Kushima I, Hashimoto R, Fukumoto M, Koike S, Ujike H, Arinami T, Tatebayashi Y, Kasai K, Takeda M, Ozaki N, Okazaki Y, Yoshikawa T, Amano N, Washizuka S, Yamamoto H, Miyata T, Itokawa M, Yamamoto Y, Arai M.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 479(3) Issue: 3 Pages: 447-452
- DOI
  10.1016/j.bbrc.2016.09.074
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-16H05380, KAKENHI-PROJECT-15K14973, KAKENHI-PROJECT-26870878, KAKENHI-PROJECT-16H05379
[Journal Article] Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex.2016
- Author(s)
  Aoyama Y, Toriumi K, Mouri A, Hattori T, Ueda E, Shimato A, Sakakibara N, Soh Y, Mamiya T, Nagai T, Kim HC, Hiramatsu M, Nabeshima T, Yamada K.
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 41(2) Issue: 2 Pages: 578-89
- DOI
  10.1038/npp.2015.186
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08218, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26870878, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-26670121, KAKENHI-PROJECT-26860175, KAKENHI-PROJECT-26293053
[Journal Article] Protective potential of the glutathione peroxidase-1 gene in abnormal behaviors induced by phencyclidine in mice.2016
- Author(s)
  Tran TV, Shin EJ, Jeong JH, Lee JW, Lee Y, Jang CG, Nah SY, Lei XG, Toriumi K, Yamada K, Nabeshima T, Kim HC.
- Journal Title
  
  Mol Neurobiol.
  
  Volume: - Issue: 9 Pages: 7042-7062
- DOI
  10.1007/s12035-016-0239-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01284, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-26870878
[Journal Article] Prenatal phencyclidine treatment induces behavioral deficits through impairment of GABAergic interneurons in the prefrontal cortex.2016
- Author(s)
  Toriumi K, Oki M, Muto E, Tanaka J, Mouri A, Mamiya T, Kim HC, Nabeshima T
- Journal Title
  
  Psychopharmacology (Berl)
  
  Volume: 233 Issue: 12 Pages: 2373-2378
- DOI
  10.1007/s00213-016-4288-8
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-15K08218, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-26870878
[Journal Article] 糖化ストレスマーカーと統合失調症2016
- Author(s)
  新井誠, 宮下光弘, 小堀晶子, 堀内泰江, 鳥海和也, 糸川昌成
- Journal Title
  
  日本生物学的精神医学会誌
  
  Volume: 27 Pages: 8-14
- NAID
  130006100373
- Data Source
  KAKENHI-PROJECT-26870878
[Journal Article] 臨床医学分野における人材育成の強化2016
- Author(s)
  新井誠, 宮下光弘, 小堀晶子, 井上智子，堀内泰江, 鳥海和也, 内田美樹，畠山幸子，小幡菜々子，野原泉，糸川昌成
- Journal Title
  
  日本生物学的精神医学会誌
  
  Volume: 27 Pages: 163-167
- NAID
  130006725645
- Data Source
  KAKENHI-PROJECT-26870878
[Journal Article] Deletion of SHATI/NAT8L decreases the N-acetylaspartate content in the brain and induces behavioral deficits, which can be ameliorated by administering N-acetylaspartate.2015
- Author(s)
  Toriumi K, Mamiya T, Song Z, Honjo T, Watanabe H, Tanaka J, Kondo M, Mouri A, Kim HC, Nitta A, Fukushima T, Nabeshima T.
- Journal Title
  
  Eur Neuropsychopharmacol.
  
  Volume: 25(11) Issue: 11 Pages: 2108-17
- DOI
  10.1016/j.euroneuro.2015.08.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08218, KAKENHI-PROJECT-15K15050, KAKENHI-PROJECT-26870878, KAKENHI-PROJECT-15H04662, KAKENHI-PROJECT-26860175
[Journal Article] 注目の遺伝子（第17回）新規薬物依存抑制因子　shati2012
- Author(s)
  鳥海和也、鍋島俊隆
- Journal Title
  
  分子精神医学
  
  Volume: 12 Pages: 133-135
- NAID
  40019300781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659213
[Journal Article] Prenatal NMDA Receptor Antagonism Impaired Proliferation of Neuronal Progenitor, Leading to Fewer Glutamatergic Neurons in the Prefrontal Cortex2012
- Author(s)
  Toriumi K, et al
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: (In press) Issue: 6 Pages: 1387-1396
- DOI
  10.1038/npp.2011.324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659213, KAKENHI-PROJECT-23790081, KAKENHI-PROJECT-23791325, KAKENHI-PROJECT-24590304, KAKENHI-PROJECT-24650433
[Journal Article] 注目の遺伝子(第17回)新規薬物依存抑制因子shati.2012
- Author(s)
  鳥海和也、鍋島俊隆
- Journal Title
  
  分子精神医学
  
  Volume: 12号 Pages: 133-135
- NAID
  40019300781
- Data Source
  KAKENHI-PROJECT-22659213
[Journal Article] Absence of SHATI/Nat8l reduces social interaction in mice.2012
- Author(s)
  Furukawa-Hibi Y, Nitta A, Fukumitsu H, Somiya H, Toriumi K, Furukawa S, Nabeshima T, Yamada K.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 526 Issue: 2 Pages: 79-84
- DOI
  10.1016/j.neulet.2012.08.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659213, KAKENHI-PROJECT-23590299
[Journal Article] Determination of N-acetylaspartic acid concentration in the mouse brain using HPLC with fluorescence detection.2012
- Author(s)
  Song Z, Ge D, Ishii K, Yamada H, Toriumi K, Watanabe H, Nabeshima T, Fukushima T.
- Journal Title
  
  Biomed Chromatogr.
  
  Volume: 26(2) Pages: 147-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659213
[Journal Article] GABAergic precursor transplantation into the prefrontal cortex prevents phencyclidine-induced cognitive deficits.2011
- Author(s)
  Tanaka DH, Toriumi K, Kubo K, Nabeshima T, Nakajima K.
- Journal Title
  
  J Neurosci.
  
  Volume: 31 Pages: 14116-14125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] 統合失調症における新規ペントシジン前駆物質グルクロン酸についての臨床学的解析2023
- Author(s)
  鳥海和也、飯野響歌、小澤有都菜、宮下光弘、鈴木一浩、田畑光一、糸川昌成、新井誠
- Organizer
  第33回日本メイラード学会年会
- Data Source
  KAKENHI-PROJECT-22K07609
[Presentation] 統合失調症に関連した新規ペントシジン合成経路の同定2023
- Author(s)
  鳥海和也、飯野響歌、小澤有都菜、宮下光弘、鈴木一浩、須川日加里、田畑光一、糸川昌成、永井竜児、上口英則、新井誠
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K07609
[Presentation] 統合失調症に関連した新規ペントシジン合成経路の同定2022
- Author(s)
  鳥海和也、飯野響歌、小澤有都菜、宮下光弘、鈴木一浩、田畑光一、糸川昌成、永井竜児、新井誠
- Organizer
  第32回日本メイラード学会年会
- Data Source
  KAKENHI-PROJECT-22K07609
[Presentation] マウスモデルを用いた統合失調症における糖化ストレス分子病態の解明2022
- Author(s)
  鳥海和也、小池伸、段孝、鈴木一浩、宮下光弘、堀内泰江、小笠原裕樹、宮田敏男、糸川昌成、新井誠
- Organizer
  第16回日本統合失調症学会年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 思春期児童における統合失調症の発症リスクと終末糖化産物の関連2022
- Author(s)
  宮下光弘、山崎修道、鈴木一浩、鳥海和也、堀内泰江、石田裕昭、今井淳司、長瀬幸弘、宮野康寛、井上智子、糸川昌成、西田淳志、新井誠
- Organizer
  第16回日本統合失調症学会年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 統合失調症における糖化ストレス蓄積の分子機序2022
- Author(s)
  鳥海和也
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-22K07609
[Presentation] 思春期児童における毛髪亜鉛濃度と統合失調症の発症リスクの関連.2022
- Author(s)
  田畑光一、宮下光弘、山崎修道、鳥海和也、鈴木一浩、高橋英彦、笠井清登、糸川昌成、西田淳志、新井誠
- Organizer
  第16回日本統合失調症学会年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 統合失調症におけるAKR1A1機能解析2022
- Author(s)
  飯野響歌、鳥海和也、東江璃子、宮下光弘、鈴木一浩、堀内泰江、糸川昌成、新井誠
- Organizer
  第16回日本統合失調症学会年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 尿中エキソソーム含有miRNAによる精神病様体験の持続の予測2022
- Author(s)
  富田康文、鈴木一浩、川路英也、宮下光弘、鳥海和也、田畑光一、山崎修道、安藤俊太郎、笠井清登、西田淳志、糸川昌成、新井誠
- Organizer
  第16回日本統合失調症学会年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] メチルグリオキサール解毒障害による統合失調症様行動異常発現の分子機序解明2022
- Author(s)
  Kazuya Toriumi, Shin Koike, Takashi Dan, Kazuhiro Suzuki, Mitsuhiro Miyashita, Yasue Horiuchi, Yuki Ogasawara, Toshio Miyata, Masanari Itokawa, Makoto Arai
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K07609
[Presentation] メチルグリオキサール解毒障害による統合失調症様行動異常発現の分子機序解明2022
- Author(s)
  鳥海和也、小池伸、段孝、鈴木一浩、宮下光弘、堀内泰江、小笠原裕樹、宮田敏男、糸川昌成、新井誠
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K07609
[Presentation] 統合失調症における糖化ストレス病態の理解2021
- Author(s)
  鳥海和也
- Organizer
  第43回日本生物学的精神医学会・第51回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] microRNA遺伝子部分欠失を伴う思春期発症カルボニルストレス性統合失調症患者の一例2021
- Author(s)
  吉川茜、久島周、鈴木一浩、宮下光弘、鳥海和也、堀内泰江、尾崎紀夫、糸川昌成、新井誠
- Organizer
  第15回日本統合失調症学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 非侵襲的測定法を用いた統合失調症と終末糖化産物（advanced glycation endproducts, AGEs）の関連研究2021
- Author(s)
  宮下光弘、鈴木一浩、鳥海和也、堀内泰江、吉川茜、江越正俊、宮野康寛、糸川昌成、新井誠
- Organizer
  第15回日本統合失調症学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] カルボニルストレス性統合失調症モデルマウスにおける脳内カルボニル化タンパク質の解析2021
- Author(s)
  小池伸、笠原桜、鳥海和也、段孝、宮田敏男、新井誠、小笠原裕樹
- Organizer
  第31回日本メイラード学会年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 胎児期メチルグリオキサール曝露が成体期マウスの行動とモノアミンに対する影響2021
- Author(s)
  王恬冉、鈴木一浩、鳥海和也、朝倉舞、正田真侑子、小澤有都菜、宮下光弘、糸川昌成、新井誠
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 思春期の低筋力はなぜ将来の精神病リスクとなるのか～糖化ストレスを軸とした縦断疫学的検討～2021
- Author(s)
  鈴木一浩、山崎修道、宮下光弘、鳥海和也、吉川茜、王恬冉、正田真侑子、富田康文、鷲塚伸介、糸川昌成、西田淳志、新井誠
- Organizer
  第117回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 思春期における終末糖化産物とメンタルヘルス：出生コホート研究によるエビデンス2021
- Author(s)
  山崎修道、宮下光弘、安藤俊太郎、鈴木一浩、鳥海和也、遠藤香織、長谷川眞理子、糸川昌成、笠井清登、西田淳志、新井誠
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] Glo1遺伝子欠損とビタミンB6欠乏による新たなカルボニルストレス性統合失調症マウスモデル.2021
- Author(s)
  鳥海和也、鈴木一浩、小池伸、宮下光弘、堀内泰江、吉川茜、小笠原裕樹、糸川昌成、新井誠
- Organizer
  第15回日本統合失調症学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 抗精神病薬未服薬思春期児童における終末糖化産物と精神病症状の関連2021
- Author(s)
  宮下光弘、山崎修道、安藤俊太郎、鈴木一浩、鳥海和也、堀内泰江、吉川茜、今井淳司、長瀬幸弘、宮野康寛、井上智子、糸川昌成、笠井清登、西田淳志、新井誠
- Organizer
  第43回日本生物学的精神医学会・第51回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 社会ストレスが統合失調症を引き起こす分子メカニズムの解明2021
- Author(s)
  正田真侑子、鈴木一浩、鳥海和也、王恬冉、糸川昌成、新井誠
- Organizer
  第31回日本メイラード学会年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 思春期児童における終末糖化産物と精神病症状の関連2021
- Author(s)
  宮下光弘、山崎修道、鈴木一浩、鳥海和也、堀内泰江、今井淳司、長瀬幸弘、宮野康寛、井上智子、糸川昌成、西田淳志、新井誠
- Organizer
  第24回日本精神保健・予防学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 統合失調症の早期発見・再発予防・セルフケアを実現するヨーガ療法を用いたスクリーニングシステムの開発2021
- Author(s)
  井上智子、榛葉俊一、糸川昌成、孫光鎬、西川真帆、宮下光弘、鈴木浩一、堀内泰江、鳥海和也、吉川茜、宮野康寛、石田裕昭、新井誠、松井岳巳
- Organizer
  第62回日本心身医学会総会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 胎児期メチルグリオキサール曝露が行動に与える長期的な影響2021
- Author(s)
  王恬冉、鈴木一浩、鳥海和也、正田真侑子、糸川昌成、新井誠
- Organizer
  第31回日本メイラード学会年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 思春期における低筋力と思考障害の関連についての縦断研究2021
- Author(s)
  鈴木一浩、山崎修道、宮下光弘、鳥海和也、吉川茜、堀内泰江、糸川昌成、西田淳志、新井誠
- Organizer
  第15回日本統合失調症学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 糖化ストレスを伴う統合失調症におけるIMMP2L遺伝子欠失-臨床特徴と新規治療法開発の可能性2021
- Author(s)
  吉川茜、久島周、宮下光弘、鈴木浩一、鳥海和也、堀内泰江、川路英哉、瀧澤俊也、尾崎紀夫、糸川昌成、新井誠
- Organizer
  第117回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] ヤマブシタケによる脳内モノアミンを介した社会性・不安様行動改善2021
- Author(s)
  王恬冉、鈴木一浩、鳥海和也、宮下光弘、朝倉舞、石田裕昭、堀内泰江、糸川昌成、新井誠
- Organizer
  第43回日本生物学的精神医学会・第51回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 思春期コホートにおける終末糖化産物と精神病症状の関連．2020
- Author(s)
  宮下光弘山崎修道、鈴木一浩, 鳥海和也、堀内泰江、吉川茜、石田裕昭、今井淳司、長瀬幸弘、宮野康寛、井上智子、糸川昌成、西田淳志、新井誠：思春期コホートにおける終末糖化産物と精神病症状の関連
- Organizer
  第30回日本メイラード学会年会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] GLO1欠損による脳内ペントシジン蓄積量の変化.2020
- Author(s)
  朝倉舞、鳥海和也、鈴木一浩、王恬冉、東江璃子、糸川昌成、新井誠
- Organizer
  第50回日本神経精神薬理学会・第42回日本生物学的精神医学会・第4回日本精神薬学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 統合失調症発症に関連する糖化エピジェネティクス機構の解明.2020
- Author(s)
  鳥海和也
- Organizer
  第4回先進医薬研究報告会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] カルボニルストレス性統合失調症の統合的CNV-microRNA解析-思春期発症の分子基盤.2020
- Author(s)
  吉川茜, 久島周, 鈴木一浩, 宮下光弘, 鳥海和也, 堀内泰江, 尾崎紀夫, 糸川昌成, 新井誠
- Organizer
  第50回日本神経精神薬理学会・第42回日本生物学的精神医学会・第4回日本精神薬学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] Hericium erinaceusによるモノアミン変動を介した抗社会的ストレス作用の検討2020
- Author(s)
  王恬冉, 鈴木一浩、鳥海和也、宮下光弘、朝倉舞、東江璃子、吉川茜、石田裕昭、堀内泰江、糸川昌成、新井誠
- Organizer
  第50回日本神経精神薬理学会・第42回日本生物学的精神医学会・第4回日本精神薬学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] モノアミン変動を介したヤマブシタケ(Hericium erinaceus)の統合失調症治療可能性の検討.2020
- Author(s)
  王恬冉, 鈴木一浩、鳥海和也、宮下光弘、東江璃子、朝倉舞、糸川昌成、新井誠
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] GLO1欠損による脳内ペントシジン蓄積量の発達段階における変化2020
- Author(s)
  朝倉舞、鳥海和也、鈴木一浩、王恬冉、東江璃子、嶌田由貴子、野原泉、糸川昌成、新井誠
- Organizer
  第93回日本生化学会大会．
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] ヨーガ療法による自律神経活動変化2019
- Author(s)
  井上智子, 榛葉俊一, 宮下光弘，鈴木一浩，堀内泰江，鳥海和也，糸川昌成，木村慧心，新井誠
- Organizer
  第115回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] カルボニルストレス性統合失調症患者由来 iPS細胞の解析2019
- Author(s)
  堀内泰江, 石川充, 小幡菜々子, 畠中真依, 許絲茵, 小池伸, 鳥海和也、宮下光弘宮岡祐一郎, 小笠原裕樹, 勝田奈那, 永井竜児, 岡野栄之, 糸川昌成, 新井誠.
- Organizer
  第29回日本メイラード学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] メチルグリオキサールに着目した統合失調症の AGEs上昇メカニズムの検討2019
- Author(s)
  鈴木一浩, 鳥海和也, 宮下光弘, 堀内泰江, 吉川茜, 小池伸, 小笠原裕樹, 鷲塚伸介, 糸川昌成, 新井誠.
- Organizer
  第29回日本メイラード学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] Vitamin B6-deficient animal model for schizophrenia with carbonyl stress.2019
- Author(s)
  Toriumi K, Suzuki K, Asakura M, Miyashita M, Horiuchi Y, Kobori A, Itokawa M, Arai M.
- Organizer
  6th Asian College of Neuropsychopharmacology (AsCNP) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] Glo1遺伝子欠損とビタミン B6欠乏がマウスの精神行動に与える影響2019
- Author(s)
  鳥海和也, 鈴木一浩, 小池伸, 宮下光弘, 堀内泰江, 吉川茜, 小笠原裕樹, 糸川昌成, 新井誠.
- Organizer
  第29回日本メイラード学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] Efficacy and side effect of Pyridoxamine for patients with schizophrenia.2019
- Author(s)
  Miyashita M, Toriumi K, Suzuki K, Horiuchi Y, Yoshikawa A, Kobori A, Itokawa M, Arai M.
- Organizer
  6th Asian College of Neuropsychopharmacology (AsCNP) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] 統合失調症における AGEsの臨床的意義2019
- Author(s)
  宮下光弘、鈴木一浩、鳥海和也、堀内泰江、吉川茜、糸川昌成、新井誠.
- Organizer
  第29回日本メイラード学会
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] The utility of patients derived Neuron/glial cells for the schizophrenia disease model.2019
- Author(s)
  Horiuchi Y, Egoshi M, Toriumi K, Miyashita M, Itokawa M, Arai M.
- Organizer
  6th Asian College of Neuropsychopharmacology (AsCNP) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] Methylglyoxal in plasma associate with anxiety in healthy individual.2019
- Author(s)
  Suzuki K, Toriumi K, Miyashita M, Yoshikawa A, Horiuchi Y, Koike S, Ogasawara Y, Itokawa M, Washizuka S, Arai M.
- Organizer
  6th Asian College of Neuropsychopharmacology (AsCNP) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] Pyridoxamine, a novel treatment for negative symptoms of schizophrenia.2018
- Author(s)
  Arai M, Miyashita M, Dan T, Toriumi K, Horiuchi H, Suzuki K, Miyata T, Itokawa M.
- Organizer
  13th International Symposium on the Maillard Reaction
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] Effect of vitamin B6-deficiency on mouse behavior and monoaminergic system2018
- Author(s)
  Kazuya Toriumi, Mitsuhiro Miyashita, Yasue Horiuchi, Kazuhiro Suzuki, Akiko Kobori, Izumi Nohara, Yukiko Shimada, Emiko Hama, Nanako Obata, Masanari Itokawa, Makoto Arai
- Organizer
  13th International Symposium on the Maillard Reaction
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977
[Presentation] グリオキサラーゼI欠損マウス脳内のメチルグリオキサールの測定2017
- Author(s)
  小池伸，西本翔一，川村久美子，鳥海和也，新井誠，小笠原裕樹
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Effect of deficiency of vitamin B6 on mouse behavior and monoaminergic system.2017
- Author(s)
  Toriumi K, Miyashita M, Horiuchi Y, Nohara I, Obata N, Konopka G, Itokawa M, Dan T, Miyata T, Arai M.
- Organizer
  WPA XVII World Congress of Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] ビタミンB6欠乏がマウスの行動及びモノアミン神経系に与える影響について.2016
- Author(s)
  鳥海和也、宮下光弘、小堀晶子、堀内泰江、野原泉、小幡菜々子、糸川昌成、Genevieve Konopka、新井誠.
- Organizer
  第59回日本神経化学会大会・第38回日本生物学的精神医学会合同年会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] High-dose pyridoxamine add-on treatement for schizophrenia with enhanced carbonyl stress.2016
- Author(s)
  Miyashita M, Arai M, Toriumi K, Ichikawa T, Horiuchi Y, Kobori A, Takahashi K, Tokunaga T, Ishimoto K, Yuzawa H, Usami S, Yoshikawa T, Okazaki Y, Washizuka S, Amano N, Takizawa S, Miyata T, Itokawa M.
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego Convention Center（USA）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] カルボニルストレスが亢進する統合失調症に対するピリドキサミン大量療法の効果の検証．2016
- Author(s)
  宮下光弘，新井誠，鳥海和也，堀内泰江，市川智恵，小堀晶子，高橋克昌，徳永太郎，石本佳代，湯澤公子，宇佐美慧，吉川武男，岡崎祐士，鷲塚伸介，天野直二，滝澤俊也，宮田敏男，糸川昌成．
- Organizer
  第59回日本神経化学会大会・第38回日本生物学的精神医学会合同年会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] 統合失調症における新たなカルボニルストレス脆弱性.2016
- Author(s)
  宮下光弘，渡邉琢夫，堀内泰恵，鳥海和也，小堀晶子，吉川武男，鷲塚伸介，山本博，糸川昌成，山本靖彦，新井誠.
- Organizer
  第112回日本精神神経学会学術総会
- Place of Presentation
  幕張メッセ（千葉県千葉市）
- Year and Date
  2016-06-02
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] 統合失調症におけるカルボニルストレス脆弱性とesRAGE.2016
- Author(s)
  宮下光弘、渡邊琢夫、堀内泰江、鳥海和也、小堀晶子、吉川武男、鷲塚伸介、糸川昌成、山本博、新井誠
- Organizer
  第11回日本統合失調症学会
- Place of Presentation
  ベイシア文化ホール (群馬県前橋市)
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Post-translational modification of FOXP1 in the developing brain.2016
- Author(s)
  Usui N, Araujo D, Co M, Berto S, Harper M, Toriumi K, Tucker HO, Konopka G.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Effect of deficiency of vitamin B6 on mouse behavior and monoaminergic system.2016
- Author(s)
  Toriumi K, Miyashita M, Kobori A, Horiuchi Y, Nohara I, Obata N, Itokawa M, Konopka G, Arai M.
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego Convention Center（USA）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Post-translational modification of FOXP1 in the developing brain.2016
- Author(s)
  Usui N, Araujo D, Co M, Berto S, Harper M, Toriumi K, Tucker HO, Konopka G.
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego Convention Center（USA）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Brain region-specific contributions of Foxp1 to autism-related phenotypes.2016
- Author(s)
  Araujo DJ, Toriumi K, Escamilla CO, Harper M, Anderson AG, Berto S, Tucker HO, Powell C, Konopka G.
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego Convention Center（USA）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Telomere shortening in the hippocampus is associated with the negative symtoms of schizophrenia.2015
- Author(s)
  Toriumi K, Miyashita M, Ichikawa T, Kobori A, Arai M, Horiuchi Y, Arai M, Nohara I, Obata N, Itokawa M.
- Organizer
  12th World Congress of Biological Psychiatry
- Place of Presentation
  Athens (Greece)
- Year and Date
  2015-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] 統合失調症の認知機能障害に対するカルボニルストレスの影響2015
- Author(s)
  小堀晶子、畠山幸子、堀内泰江、鳥海和也、宮下光弘、糸川昌成、新井平伊、新井誠
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  タワーホール船堀 (東京都江戸川区)
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] 海馬のテロメア短縮は統合失調症の陰性症状及び認知機能障害に関与する2015
- Author(s)
  鳥海和也、宮下光正、市川智恵、新井麻友美、野原泉、小堀晶子、堀内泰江、橋本均、糸川昌成、新井誠
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  タワーホール船堀 (東京都江戸川区)
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] 統合失調症患者由来神経細胞-グリア間代謝的相互作用の解析2015
- Author(s)
  堀内泰江、鳥海和也、糸川昌成、岡野栄之、新井誠
- Organizer
  第48回精神神経系薬物治療研究報告会
- Place of Presentation
  千里ライフサイエンスセンター (大阪府豊中市)
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Study for the effect of carbonyl stress makers on congnitive impairment of schizophrenia.2015
- Author(s)
  Kobori A, Hatakeyama S, Horiuchi Y, Toriumi K, Miyashita M, Itokawa M, Arai H, Arai M.
- Organizer
  Society for Neuroscience 45th Annual Meeting
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Effect of carbonyl stress on congnitive impairment in schizophenia patients.2015
- Author(s)
  Kobori A, Hatakeyama S, Arai M, Horiuchi Y, Toriumi K, Miyashita M, Arai H, Itokawa M.
- Organizer
  12th World Congress of Biological Psychiatry
- Place of Presentation
  Athens (Greece)
- Year and Date
  2015-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Pentosidene accumulation in the pathophysiology of Schizophrenia.2015
- Author(s)
  Arai M, Horiuchi Y, Kobori A, Miyashita M, Toriumi T, Hashimoto H, Itokawa M.
- Organizer
  Society for Neuroscience 45th Annual Meeting
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Telomere shortening in the hippocampus is associated with negative symptom-like behavioral deficits in scizophrenia.2015
- Author(s)
  Toriumi K, Miyashita M, Ichikawa T, Nohara I, Kobori A, Obata N, Horiuchi Y, Arai M, Hashimoto H, Itokawa M.
- Organizer
  Society for Neuroscience 45th Annual Meeting
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Effect of antipsychotics on telomere length in the hippocampus.2014
- Author(s)
  Toriumi K, Miyashita M, Ichikawa T, Kobori A, Nohara I, Arai M, Obata N, Itokawa M
- Organizer
  CINP2014
- Place of Presentation
  バンクーバー（カナダ）
- Year and Date
  2014-06-24
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] Telomere shortening in the hippocampus is associated with negative symptom-like behavioral deficits and cognitive impairment in schizophrenia.2014
- Author(s)
  Kazuya Toriumi, Mitsuhiro Miyashita, Tomoe Ichikawa, Mayumi Arai, Izumi Nohara, Nanako Obata, Akiko Kobori, Yasue Horiuchi, Makoto Arai, Masanari Itokawa.
- Organizer
  第24回日本臨床精神神経薬理学会・第44回日本神経精神薬理学会合同年会
- Place of Presentation
  名古屋国際会議場（愛知・名古屋市）
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-26870878
[Presentation] SHATI/NAT8Lは微小管の安定化により神経突起の伸展を制御する2013
- Author(s)
  伊神実紀、鳥海和也、近藤水生、毛利彰宏、古関竹直、間宮隆吉、鍋島俊隆
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] SHATI/NAT8Lの欠損は側坐核における細胞表面上のドパミン受容体を増加させ、メタンフェタミンによる薬物依存を増悪させる.2013
- Author(s)
  鳥海和也ら
- Organizer
  第86回薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] SHATI/NAT8L の欠損は側坐核における細胞表面上のドパミン受容体を増加させ、メタンフェタミンによる薬物依存を増悪させる2013
- Author(s)
  鳥海和也、近藤水生、永井拓、毛利彰宏、古関竹直、間宮隆吉、新田淳美、山田清文、鍋島俊隆
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] New psysiologincal functions of drug dependence regulating molecule, shati.2012
- Author(s)
  Toshitaka Nabeshima, Kazuya Toriumi, Atumi Nitta
- Organizer
  21th Century Frontier R & D Program in Neuroscience,BRC International Conference 2012 @Jeju
- Place of Presentation
  Jeju
- Invited
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] A nobel molecule "SHATI" inhibiting methamphetamine dependence2012
- Author(s)
  Toshitaka Nabeshima, Kazuya Toriumi, Minae Niwa, Atumi Nitta
- Organizer
  The 16th Congress of International Sociery for Biomedical Research on Alcoholosm (ISBRA2012)
- Place of Presentation
  Sapporo
- Invited
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] 胎生期におけるフェンサイクリジンの投与は神経前駆細胞の分裂を障害し、前頭前皮質内グルタミン酸作動性神経細胞数の減少を生じる2012
- Author(s)
  鳥海和也
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] 胎生期におけるフェンサイクリジンの投与は神経前駆細胞の分裂を障害し、前頭前皮質内グルタミン酸作動2012
- Author(s)
  鳥海和也ら
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] 胎生期のニコチン暴露が神経発達に与える影響2011
- Author(s)
  服部友哉、青山雄紀、Alkam Tursun、鳥海和也、山田清文、鍋島俊隆
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] shati遺伝子欠損マウスにおける行動異常と脳内の神経化学的な変化2011
- Author(s)
  本荘龍輝、鳥海和也、渡辺裕之、宋梓瑜、近藤水生、武藤瑛里子、間宮隆吉、新田淳美、福島健、鍋島俊隆
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] 新規薬物依存抑制因子shatiは微小管の安定化に関与する2011
- Author(s)
  鳥海和也、近藤水生、本荘龍輝、武藤瑛里子、永井拓、宋梓瑜、新田淳美、山田清文、福島健、鍋島俊隆
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] 依存性薬物による精神障害への冬季出産の影響2011
- Author(s)
  布目貴大、毛利彰宏、青山雄紀、鳥海和也、古関竹直、間宮隆吉、鍋島俊隆
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] HPLC-蛍光定量法によるShati遺伝子欠損マウス脳組織中N-アセチルアスパラギン酸の変動解析2011
- Author(s)
  福島健、宋梓瑜、葛丹、鳥海和也、渡辺裕之、鍋島俊隆
- Organizer
  第24回バイオメディカル分析科学シンポジウム
- Place of Presentation
  鳥取
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] Enriched Environment in Adolescent Prevents Abnormal Behavior Associated with Histone Deacetylation in Phencyclidine-treated Mice2011
- Author(s)
  Takeonao Koseki, Akihiro Mouri, Takayoshi Mamiya, Yuki Aoyama, Kazuya Toriumi, Shizuka Suzuki, Azusa nakajima, Takuma Yamada, Taku Nagai, Toshitaka Nabeshima
- Organizer
  The 2nd congress of Asian colleage of Neuropsyichophamacology
- Place of Presentation
  Seoul
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] 新規薬物依存抑制因子Shatiの機能解析2011
- Author(s)
  鳥海和也ら
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  金沢
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-22659213
[Presentation] 新規薬物依存抑制因子shati結合タンパク質の探索2011
- Author(s)
  近藤水生、鳥海和也、本荘龍輝、武藤瑛里子、古関竹直、間宮隆吉、永井拓、新田淳美、山田清文、鍋島俊隆
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-22659213
[]
[]

1. NABESHIMA Toshitaka (70076751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
2. 西田淳志 (20510598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 松川岳久 (60453586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 長谷川眞理子 (00164830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HORIUCHI Yasue

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. MIYASHITA Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. YOSHIKAWA Akane

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. MOURI Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 森本裕子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 中嶋智史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 新井誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 間宮隆吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 新田淳美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 山田清文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 岡田俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Toriumi Kazuya 鳥海 和也

TORIUMI Kazuya 鳥海 和也

Research Projects

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AGEs蓄積による精神疾患の早期老化病態：疫学研究を起点とする分子基盤の解明Principal Investigator

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若者の老化ペースを速める胎内から思春期までの要因とその予防戦略に関する研究

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Elucidation of the molecular pathogenesis of schizophrenia based on a novel pentosidine-producing pathwayPrincipal Investigator

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Study on mechanism underlying schizophrenia development by carbonyl stressPrincipal Investigator

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Study on molecular mechanism for telomere shortening induced by stress exposure on schizophreniaPrincipal Investigator

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Aimed at clinical application, functional analysis of a novelmolecule "SHATI" by proteomics-like technique.

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[Journal Article] Association of homocysteine with white matter dysconnectivity in schizophrenia2024

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[Journal Article] Urinary exosomal microRNAs as predictive biomarkers for persistent psychotic-like experiences2023

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[Journal Article] Glucuronic acid is a novel source of pentosidine, associated with schizophrenia2023

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[Journal Article] Association between enhanced carbonyl stress and decreased apparent axonal density in schizophrenia by multimodal white matter imaging2023

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[Journal Article] Hair zinc levels and psychosis risk among adolescents2022

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[Journal Article] Exonic deletions in IMMP2L in schizophrenia with enhanced glycation stress subtype.2022

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[Journal Article] Role of glyoxalase 1 in methylglyoxal detoxification?the broad player of psychiatric disorders2022

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[Journal Article] Cross-disorder analysis of genetic and regulatory copy number variations in bipolar disorder, schizophrenia, and autism spectrum disorder2022

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Toriumi Kazuya 鳥海和也

TORIUMI Kazuya 鳥海和也