MATSUMOTO Junichi 松本純一

… Alternative Names

Matsumoto Junichi 松本純一

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Researcher Number	10550064
Other IDs
Affiliation (Current)	2025: 福岡大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2019 – 2025: 福岡大学, 薬学部, 助教 2013 – 2014: 福岡大学, 薬学部, 助教 2010: 福岡大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Biological pharmacy / Basic Section 48030:Pharmacology-related / Medical pharmacy
Keywords	Principal Investigator COPD / 肺気腫 / T細胞 / テストステロン / 細胞外小胞 / エクソソーム / extracellular vesicle / BBB / 慢性閉塞性肺疾患 / 血液脳関門 … More Except Principal Investigator … More 慢性閉塞性肺疾患 / 血液脳関門 / 脳ペリサイト / テストステロン / 抗うつ薬 / 肺障害 / 接着因子 / 血管透過性 / 細胞間接着因子 / ボルテゾミブ / 薬剤性肺障害 / 肺気腫モデルマウス / 男性更年期 / フルタミド / 抗アンドロゲン薬 / COPD / 炎症性サイトカイン / オートファジー / Toll様受容体 / P糖タンパク質 / 炎症性メディエーター / 炎症性腸疾患 / αシヌクレイン / パーキンソン病 / レニン－アンギオテンシン系 / レニンーアンギオテンシン系 / レニン-アンギオテンシン系 / 副作用 / レニンーアンジオテンシン系 / シクロフィリンＡ / 視床下部神経 / 脂質ラフト / メチルグリオキサール / 糖尿病 / シクロフィリンA / インスリン抵抗性 / GT1-7 / ペリサイト / 脳インスリン抵抗性 / cyclophilin A / MMP-9 / 肥満 / 神経生物学 Less

アンドロゲンシグナルを軸としたCOPD全身性併存症の病態解明と包括的治療戦略の確立Principal Investigator
- Principal Investigator
  
  松本純一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
慢性閉塞性肺疾患COPD併存うつ病の治療薬による原疾患増悪ジレンマのメカニズム
- Principal Investigator
  
  山内淳史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
アンドロゲンシグナルから捉えるCOPD病態の解析と治療薬の探索Principal Investigator
- Principal Investigator
  
  松本純一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
アンドロゲンを核とする内分泌系－肺－脳の臓器連関異常化によるCOPD病態増悪機構
- Principal Investigator
  
  山内淳史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
Invovlvement of increased vascular permeability in bortezomib-induced lung toxicity
- Principal Investigator
  
  Matsumoto Taichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Our Lady of the Snow Social Medical Corporation (St. Mary
  Fukuoka University
Involvement of activated brain pericytes induced by inflammatory bowel disease in the increased aggregation of alpha-synuclein in the brain.
- Principal Investigator
  
  DOHGU Shinya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fukuoka University
Decreased expression of OATP2a1 in porcine pancreas elastase-induced COPD mouse model.Principal Investigator
- Principal Investigator
  
  Matsumoto Junichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
Blood-brain barrier function change in the chronic obstructive pulmonary disease and protective effect of the renin-angiotensin system inhibitors
- Principal Investigator
  
  TOMINAGA Koji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Fukuoka University
Involvement of pericytes-derived cyclophilin A in the development of insulin resistanse in the brain
- Principal Investigator
  
  TAKATA Fuyuko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Fukuoka University
Involvement of brain pericytes in the development of obesity
- Principal Investigator
  
  TAKATA Fuyuko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Fukuoka University

All 2024 2023 2022 2021 2020 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Patent Other

[Journal Article] Dynamic Changes of Behavioral Despair, HPA Axis Activity, and Hippocampal Neurogenesis in Male Rats Induced by Social Defeat Stress.2023
- Author(s)
  Harada H, Mori M, Murata Y, Kawanabe S, Terada K, Matsumoto T, Ohe K, Enjoji M.
- Journal Title
  
  J Integr Neurosci.
  
  Volume: 22 Issue: 2 Pages: 43-43
- DOI
  10.31083/j.jin2202043
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06703, KAKENHI-PROJECT-20K07110, KAKENHI-PROJECT-20K16657, KAKENHI-PROJECT-22K06713, KAKENHI-PROJECT-23K07000
[Journal Article] Association of T cell infiltration and morphological change of thymus gland with the aggravation of pulmonary emphysema in testosterone deficiency2023
- Author(s)
  Aono Kentaro、Matsumoto Junichi、Matsumoto Taichi、Koga Mitsuhisa、Migita Keisuke、Tominaga Koji、Nakagawa Shinsuke、Yamauchi Atsushi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 34 Pages: 101489-101489
- DOI
  10.1016/j.bbrep.2023.101489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06683, KAKENHI-PROJECT-22K06715, KAKENHI-PROJECT-21K06703, KAKENHI-PROJECT-23K27951
[Journal Article] Aging decreases docosahexaenoic acid transport across the blood-brain barrier in C57BL/6J mice2023
- Author(s)
  Iwao T, Takata F, Matsumoto J, Aridome H, Yasunaga M, Yokoya M, Kataoka Y, Dohgu S.
- Journal Title
  
  PLoS One.
  
  Volume: 18 Issue: 2 Pages: e0281946-e0281946
- DOI
  10.1371/journal.pone.0281946
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06703, KAKENHI-PROJECT-20K16065
[Journal Article] Senescence in brain pericytes attenuates blood-brain barrier function in vitro: A comparison of serially passaged and isolated pericytes from aged rat brains.2023
- Author(s)
  Iwao T, Takata F, Matsumoto J, Goto Y, Aridome H, Yasunaga M, Yokoya M, Kataoka Y, Dohgu S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 645 Pages: 154-163
- DOI
  10.1016/j.bbrc.2023.01.037
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06703, KAKENHI-PROJECT-20K16065
[Journal Article] Inhibitory Effect of Pyra-Metho-Carnil on Cancer Spheroid Growth Through Decrease in Glycolysis-associated Molecules2023
- Author(s)
  Yoshida K, Nishi K, Ishikura S, Matsumoto T, Nakabayashi K, Yazaki R, Ohshima T, Suenaga M, Shirasawa S, Tsunoda T.
- Journal Title
  
  Anticancer Res
  
  Volume: 43 Issue: 8 Pages: 3717-3726
- DOI
  10.21873/anticanres.16556
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06703, KAKENHI-PLANNED-21H05208, KAKENHI-PROJECT-21H02607
[Journal Article] Impact of Concomitant Use of Azoles on Bortezomib-related Adverse Drug Reactions Using JADER.2023
- Author(s)
  Imatoh T, Matsumoto T, Haramaki Y, Migita K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 43 Issue: 3 Pages: 1341-49
- DOI
  10.21873/anticanres.16282
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06703, KAKENHI-PROJECT-20K20865
[Journal Article] evetiracetam Suppresses the Infiltration of Neutrophils and Monocytes and Downregulates Many Inflammatory Cytokines during Epileptogenesis in Pilocarpine-Induced Status Epilepticus Mice.2022
- Author(s)
  Matsuo T, Komori R, Nakatani M, Ochi S, Yokota-Nakatsuma A, Matsumoto J, Takata F, Dohgu S, Ishihara Y, Itoh K.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 23 Issue: 14 Pages: 7671-7671
- DOI
  10.3390/ijms23147671
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06703, KAKENHI-PROJECT-15K18947
[Journal Article] Effects of Aspergillus fumigatus Conidia on Apoptosis and Proliferation in an In Vitro Model of the Lung Microenvironment2021
- Author(s)
  Kushima Hisako、Tsunoda Toshiyuki、Matsumoto Taichi、Kinoshita Yoshiaki、Izumikawa Koichi、Shirasawa Senji、Fujita Masaki、Ishii Hiroshi
- Journal Title
  
  Microorganisms
  
  Volume: 9 Issue: 7 Pages: 1435-1435
- DOI
  10.3390/microorganisms9071435
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08840, KAKENHI-PROJECT-21K06703, KAKENHI-PROJECT-21K07161, KAKENHI-PROJECT-18K15154
[Journal Article] Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction2021
- Author(s)
  Fuyuko Takata, Shinsuke Nakagawa, Junichi Matsumoto, Shinya Dohgu
- Journal Title
  
  Frontiers in Cellular Neuroscience.
  
  Volume: 15 Pages: 661838-661838
- DOI
  10.3389/fncel.2021.661838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07338, KAKENHI-PROJECT-20K09394, KAKENHI-PROJECT-21K06703
[Journal Article] Testosterone deficiency promotes the development of pulmonary emphysema in orchiectomized mice exposed to elastase2021
- Author(s)
  Aono K, Matsumoto J, Nakagawa S, Matsumoto T, Koga M, Migita K, Tominaga K, Sakai Y, Yamauchi A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 558 Pages: 94-101
- DOI
  10.1016/j.bbrc.2021.04.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16433, KAKENHI-PROJECT-21K06683, KAKENHI-PROJECT-21K06703
[Journal Article] Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization2021
- Author(s)
  Bisht Kavita、McGirr Crystal、Lee Seo-Youn、Tseng Hsu-Wen、Fleming Whitney、Alexander Kylie A.、Matsumoto Taichi、Barbier Valerie、Sims Natalie A.、Muller-Newen Gerhard、Winkler Ingrid G.、Bonig Halvard、Levesque Jean-Pierre
- Journal Title
  
  Leukemia
  
  Volume: 36 Issue: 2 Pages: 333-347
- DOI
  10.1038/s41375-021-01413-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06703
[Journal Article] A refractory human T-cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis patient with lymphoma-type adult T-cell leukemia/lymphoma: A case report and review of the literature.2021
- Author(s)
  Tamaki K, Mera H, Takeshita S, Fujioka S, Goto M, Matsumoto T, Yamano Y, Takamatsu Y, Tsuboi Y.
- Journal Title
  
  Medicine(Baltimore)
  
  Volume: 100(40) Issue: 40 Pages: e27450-e27450
- DOI
  10.1097/md.0000000000027450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-21K06703
[Journal Article] In vitro blood-brain barrier models using brain capillary endothelial cells isolated from neonatal and adult rats retain age-related barrier properties.2013
- Author(s)
  Takata, F
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 1 Pages: 55166-55166
- DOI
  10.1371/journal.pone.0055166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240034, KAKENHI-PROJECT-21700422, KAKENHI-PROJECT-22590163, KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790113, KAKENHI-PROJECT-23790287
[Journal Article] Metformin induces up-regulation of blood-brain barrier functions by activating AMP-activated protein kinase in rat brain microvascular endothelial cells.2013
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Machida T, Kaneshima S, Matsuo M, Sakaguchi S, Takeshige Y, Yamauchi A, Kataoka Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 19; 433(4) Issue: 4 Pages: 586-590
- DOI
  10.1016/j.bbrc.2013.03.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790113, KAKENHI-PROJECT-25460236
[Journal Article] Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells.2012
- Author(s)
  Matsumoto J, Dohgu S, Takata F, Nishioku T, Sumi N, Machida T, Takahashi H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 524(1) Issue: 1 Pages: 45-8
- DOI
  10.1016/j.neulet.2012.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590163, KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790113, KAKENHI-PROJECT-23790311
[Journal Article] Partial hepatectomy aggravates cyclosporin A-induced neurotoxicity by lowering the function of the blood-brain barrier in mice.2011
- Author(s)
  Yamauchi A, Dohgu S, Takata F, Watanabe T, Nishioku T, Matsumoto J, Ohkubo Y, Shuto H, Kataoka Y.
- Journal Title
  
  Life Sci.
  
  Volume: 88(11-12) Pages: 529-534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Partial hepatectomy aggravates cyclosporin A-induced neurotoxicity by lowering the function of the blood-brain barrier in mice.2011
- Author(s)
  Yamauchi A, Dohgu S, Takata F, Watanabe T, Nishioku T, Matsumoto J, Ohkubo Y, Shuto H, Kataoka Y.
- Journal Title
  
  Life Sci. 88(11-12)
  
  Pages: 529-534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro2011
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Takahashi H, Machida T, Wakigawa T, Harada E, Miyaji H, Koga M, Nishioku T, Yamauchi A, Kataoka Y.
- Journal Title
  
  J Neuroinflammation.
  
  Volume: 8 Issue: 1 Pages: 106-106
- DOI
  10.1186/1742-2094-8-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790113, KAKENHI-PROJECT-23790311
[Journal Article] Autocrine and paracrine up-regulation of blood-brain barrier function by plasminogen activator inhibitor-1.2011
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Oda M, Harada E, Watanabe T, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Microvasc Res.
  
  Volume: 81(1) Pages: 103-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Autocrine and paracrine up-regulation of blood-brain barrier function by plasminogen activator inhibitor-1.2011
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Oda M, Harada E, Watanabe T, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Microvasc Res. 81(1)
  
  Pages: 103-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Lipopolysaccharide-activated microglia induce dysfunction of the blood-brain barrier in rat microvascular endothelial cells co-cultured with microglia.2010
- Author(s)
  Sumi N, Nishioku T, Takata F, Matsumoto J, Watanabe T, Shuto H, Yamauchi A, Dohgu S, Kataoka Y.
- Journal Title
  
  Cell Mot Neurobiol. 30(2)
  
  Pages: 247-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Tumor necrosis factor-alpha mediates the blood-brain barrier dysfunction induced by activated microglia in mouse brain microvascular endothelial cells2010
- Author(s)
  Nishioku T, Matsumoto J, Dohgu S, Sumi N, Miyao K, Takata F, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  J Pharmacol Sci. 112(2)
  
  Pages: 251-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Lipopolysaccharide-activated microglia induce dysfunction of the blood-brain barrier in rat microvascular endothelial cells co-cultured with microglia2010
- Author(s)
  Sumi N, Nishioku T, Takata F, Matsumoto J, Watanabe T, Shuto H, Yamauchi A, Dohgu S, Kataoka Y.
- Journal Title
  
  Cell Mol Neurobiol. 30(2)
  
  Pages: 247-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Journal Article] Tumor necrosis factor-alpha mediates the blood-brain barrier dysfunction induced by activated microglia in mouse brain microvascular endothelial cells.2010
- Author(s)
  Nishioku T, Matsumoto J, Dohgu S, Sumi N, Miyao K, Takata F, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  J Pharmacol Sci. 112(2)
  
  Pages: 251-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790102
[Patent] 血液脳関門障害症候群治療薬2011
- Inventor(s)
  高田芙友子、道具伸也、片岡泰文、松本純一、金嶋修司
- Industrial Property Rights Holder
  福岡大学
- Industrial Property Rights Type
  特許
- Filing Date
  2011-12-12
- Overseas
- Data Source
  KAKENHI-PROJECT-23790113
[Patent] 血液脳関門障害症候群治療薬2011
- Inventor(s)
  高田芙友子、道具伸也、片岡泰文、松本純一、金嶋修司
- Industrial Property Rights Holder
  福岡大学
- Filing Date
  2011
- Overseas
- Data Source
  KAKENHI-PROJECT-23790113
[Patent] 血液脳関門障害症候群治療薬2010
- Inventor(s)
  高田芙友子、片岡泰文、道具伸也、松本純一、金嶋修司
- Industrial Property Rights Holder
  福岡大学
- Industrial Property Number
  2010-277027
- Filing Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-21790102
[Patent] 血液脳関門障害症候群治療薬2010
- Inventor(s)
  高田芙友子、道具伸也、片岡泰文、松本純一、金嶋修司
- Industrial Property Rights Holder
  福岡大学
- Industrial Property Number
  2010-277027
- Filing Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] PPE誘発肺気腫モデルマウスにおける脳トランスポーター遺伝子発現量の解析2024
- Author(s)
  松本純一、道具伸也、青野健太郎、中川慎介、稲田紘舜、山内淳史
- Organizer
  第144回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-22K06715
[Presentation] フルタミドによるアンドロゲンシグナル阻害はPPE誘発肺気腫形成を増悪させる2023
- Author(s)
  青野健太郎、松本純一、松本太一、戸田吉香、原田果歩、山内淳史
- Organizer
  第40回日本薬学部九州山口支部大会
- Data Source
  KAKENHI-PROJECT-21K06683
[Presentation] フルタミドによるアンドロゲンシグナル阻害はPPE誘発肺気腫形成を増悪させる2023
- Author(s)
  青野健太郎、松本純一、松本太一、戸田吉香、原田果歩、山内淳史
- Organizer
  第40回日本薬学部九州山口支部大会
- Data Source
  KAKENHI-PROJECT-22K06715
[Presentation] Cyclophillin A is involved in the uptake of oligomericα-synuclein by brain pericytes2022
- Author(s)
  Miki Yokoya, Fuyuko Takata, Takuro Iwao, Junichi Matsumoto, Miho Yasunaga, Hisataka Aridome, Shinya Dohgu
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] 進行リスクの高い異常形質細胞を特徴づける細胞表面バイオマーカーの探索2022
- Author(s)
  Taichi Matsumoto, Nobukazu Watanabe, Shotaro Chinen, Ilseung Choi, Kentaro Kouno, Tsuyoshi Muta, Tomoko Narita, Takuto Tachita, Hidenori Sasaki, Shinichiro Yasunaga, Shinsuke Iida, Yasushi Takamatsu
- Organizer
  第47回日本骨髄腫学会
- Data Source
  KAKENHI-PROJECT-21K06703
[Presentation] アンドロゲン受容体シグナルの阻害はエラスターゼ誘発肺気腫形成を増悪させる2022
- Author(s)
  青野健太郎、松本純一、松本太一、池田弥恵、河村莉奈、山内淳史
- Organizer
  第96回日本薬理学会年会/第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06683
[Presentation] Involvement of P-glycoprotein in α-synuclein aggregate-induced inflammatory mediator release by brain pericytes2022
- Author(s)
  Shinya Dohgu, Miki Yokoya, Minami Akizuki, Atsushi Kobayashi, Fuyuko Takata, Takuro 　　　　　　Iwao, Junichi Matsumoto, Hisataka Aridome, Miho Yasunaga, Kazunori Sano
- Organizer
  4th Mini-Symposium on the Blood-Brain Barrier from Basic to Clinical Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] アンドロゲン受容体シグナルの阻害はエラスターゼ誘発肺気腫形成を増悪させる2022
- Author(s)
  青野健太郎、松本純一、松本太一、池田弥恵、河村莉奈、山内淳史
- Organizer
  第96回日本薬理学会年会/第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06703
[Presentation] 骨髄異形成症候群のアザシチジン治療感受性を決める新規遺伝子の同定2022
- Author(s)
  Taichi Matsumoto, Yuichi Murakami, Daisuke Katsuchi, Michihiko Kuwano, Mayumi Ono
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06703
[Presentation] アンドロゲン受容体シグナルの阻害はエラスターゼ誘発肺気腫形成を増悪させる2022
- Author(s)
  青野健太郎、松本純一、松本太一、池田弥恵、河村莉奈、山内淳史
- Organizer
  第96回日本薬理学会年会/第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06715
[Presentation] Involvement of P-glycoprotein in α-Synuclein aggregate-induced inflammatory mediator release by brain pericytes2022
- Author(s)
  Shinya Dohgu, Miki Yokoya, Minami Akizuki, Atsushi Kobayashi, Fuyuko Takata, Takuro Iwao, Junichi Matsumoto, Hisataka Aridome, Miho Yasunaga, Kazunori Sano
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] Degradation of oligomeric α-Synuclein in brain pericytes is enhanced by cyclosporin A.2021
- Author(s)
  道具伸也、横谷みき，髙田芙友子，松本純一，岩尾卓朗，佐野和憲，片岡泰文
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] 1.精巣摘出マウスにおけるテストステロン欠乏に伴う胸腺の変化と肺気腫形成の関連性2021
- Author(s)
  青野健太郎、松本純一、河村莉奈、松本太一、右田啓介、道具伸也、山内淳史
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2021
- Data Source
  KAKENHI-PROJECT-21K06683
[Presentation] 精巣摘出マウスにおけるテストステロン欠乏に伴う胸腺の変化と肺気腫形成の関連性2021
- Author(s)
  青野健太郎、松本純一、河村莉奈、松本太一、右田啓介、道具伸也、山内淳史
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2021
- Data Source
  KAKENHI-PROJECT-19K16433
[Presentation] 肝細胞がん細胞が放出するosteopontinはマクロファージにおける腫瘍促進性サイトカイン発現を促進する2021
- Author(s)
  箱丸　雄大、松本　太一、森山　英恵、寺井　大樹、右田　啓介
- Organizer
  第38回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-21K06703
[Presentation] 非定型抗精神病薬ジプラシドンによるミトコンドリア機能障害の改善効果2021
- Author(s)
  １.寺田一樹，村田亜侑美，松本太一，森征慶，松嶋ゆかり，加留部善晴
- Organizer
  第51回日本神経精神薬理学会合同大会
- Data Source
  KAKENHI-PROJECT-21K06703
[Presentation] ボルテゾミブは血管内皮細胞の細胞接着分子発現を抑制する2021
- Author(s)
  野口　誉真、松本　太一、松本　純一、森山　英恵、寺井　大樹、山内　淳史、右田　啓介
- Organizer
  第38回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-21K06703
[Presentation] ボルテゾミブによる造血幹細胞動員促進作用―CXCL12抑制と血管透過性亢進の関与―2021
- Author(s)
  松本　太一、高松　泰、森山　英恵、寺田　一樹、森　征慶、小野　和彦、右田　啓介、原　周司
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06703
[Presentation] 多発性骨髄腫におけるTACI発現と細胞増殖能の関係2021
- Author(s)
  森山　英恵、松本　太一、寺井　大樹、高松　泰、右田　啓介
- Organizer
  第38回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-21K06703
[Presentation] 精巣摘出マウスにおけるテストステロン欠乏に伴う胸腺の変化と肺気腫形成の関連性2021
- Author(s)
  青野健太郎、松本純一、河村莉奈、松本太一、右田啓介、道具伸也、山内淳史
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2021
- Data Source
  KAKENHI-PROJECT-21K06703
[Presentation] 2)Toll様受容体を介した脳ペリサイト特異的なαシヌクレインによる炎症性メディエーター産生2020
- Author(s)
  道具伸也、秋月美波、小林篤史、盛田隼矢、高田芙友子、松本純一、岩尾卓朗、山内淳史、佐野和憲、片岡泰文
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] 1)脳ペリサイトによるα－シヌクレインオリゴマーの細胞内取り込み機構2020
- Author(s)
  横谷みき、道具伸也、高田芙友子、松本純一、岩尾卓朗、山内淳史、佐野和憲、片岡泰文
- Organizer
  日本薬学会第140回年会
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] 5)Involvement of Toll-like receptors in brain pericyte specific production of inflammatory mediators induced by α-synuclein2020
- Author(s)
  Shinya Dohgu, Minami Akizuki, Atsushi Kobayashi, Shunya Morita, Fuyuko Takata, Junichi Matsumoto, Takuro Iwao, Atsushi Yamauchi, Kazunori Sano, Yasufumi Kataoka
- Organizer
  2nd Mini-symposium on the blood-brain barrier from basic to clinical research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07338
[Presentation] 脳ペリサイト由来液性因子による血液脳関門障害2013
- Author(s)
  道具伸也、高田芙友子、松本純一、町田崇、高橋弘之、山内淳史、片岡泰文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] メトホルミンによる血液脳関門機能強化2013
- Author(s)
  高田芙友子、道具伸也、松本純一、町田崇、山内淳史、片岡泰文
- Organizer
  第15回応用薬理シンポジウム
- Place of Presentation
  コクヨホール
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] 脳ペリサイトはマクロファージの脳実質内浸潤を阻害する2012
- Author(s)
  道具伸也、高田芙友子、松本純一、高橋弘之、町田崇、一木奈津子、関菜摘子、山内淳史、片岡泰文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] 脳ペリサイトは血液脳関門構成細胞のなかで最大のTNF-α誘発性MMP-9産生能と細胞遊走能を有する2012
- Author(s)
  高田芙友子、道具伸也、松本純一、町田崇、高橋弘之、山内淳史、片岡泰文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] 脳ペリサイトに特異的なTNF-α誘発性MMP-9産生における活性酸素種およびERK1/2・Aktの遅延的活性化の関与2012
- Author(s)
  町田崇、道具伸也、高田芙友子、松本純一、高橋弘之、宮地晴樹、園木優唯、山内淳史、片岡泰文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] インスリンによる視床下部神経細胞のAkt活性化に対する脳ペリサイトの促進的関与2011
- Author(s)
  高橋弘之、道具伸也、高田芙友子、松本純一、渡辺拓也、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 血液脳関門における脳ペリサイト特異的なTNF-α誘発性MMP-9産生・放出機構2011
- Author(s)
  宮地晴樹、道具伸也、高田芙友子、松本純一、高橋弘之、園木優唯、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 低酸素病態下での脳ペリサイトMMP-9産生における脳血管内皮細胞由来CD39/ENTPDaselの作用2011
- Author(s)
  古野龍也、高田芙友子、松本純一、高橋弘之、南里朋、山内淳史、道具伸也、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] インスリンによる視床下部神経細胞のAkt活性化に対する脳ペリサイトの促進的関与2011
- Author(s)
  高橋弘之、道具伸也、高田芙友子、松本純一、渡辺拓也、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 血液脳関門における脳ペリサイト特異的なTNF-α誘発性MMP-9産生・放出機構2011
- Author(s)
  宮地晴樹、道具伸也、高田芙友子、松本純一、高橋弘之、園木優唯、山内淳史、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 低酸素病態下での脳ペリサイトMMP-9産生における脳血管内皮細胞由来CD39/ENTPDase1の作用2011
- Author(s)
  古野龍也、高田芙友子、松本純一、高橋弘之、南里朋、山内淳史、道具伸也、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 脳ペリサイトのIL-6放出機構2011
- Author(s)
  松本純一、道具伸也、高田芙友子、堂籠航、川口真奈美、山内淳史、片岡泰文
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  KKRホテル博多
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-23790113
[Presentation] Impaired blood-brain barrier functions in the pre-diabetic mice.2010
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Takahashi H, Watanabe T, Koga M, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13th International Blood-Brain Barrier Symposium Zurich
- Place of Presentation
  Switzerland
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] カルシニューリン/NFAT経路を介した脳ペリサイトのMMP-9産生機構2010
- Author(s)
  町田崇、道具伸也、高田芙友子、松本純一、古野龍也、金嶋修司、渡辺拓也、首藤英樹、山内淳史、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] Impaired blood-brain barrier functions in the pre-diabetic mice.2010
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Takahashi H, Watanabe T, Koga M, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13^<th> international symposium signaling at blood-brain and blood-retinal barrier
- Place of Presentation
  Zurich(スイス)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] NADPH oxidase-derived reactive oxygen species (ROS) facilitate TNF-alpha-induced up-regulation of MMP-9 production in the brain pericytes through Akt activation.2010
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Machida T, Furuno T, Ichiki N, Kaneshima S, Miyaji H, Tao S, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13th International Blood-Brain Barrier Symposium Zurich
- Place of Presentation
  Switzerland
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] NADPH oxidase-derived reactive oxygen species (ROS) facilitate TNF-alpha-induced up-regulation of MMP-9 production in the brain pericytes through Akt activation.2010
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Machida T, Furuno T, Ichiki N, Kaneshima S, Miyaji H, Tao S, Shuto H, Yamauchi A, Kataoka Y.
- Organizer
  13^<th> international symposium signaling at blood-brain and blood-retinal barrier
- Place of Presentation
  Zurich(スイス)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 肥満および耐糖能異常を呈したマウスにおける血液脳関門機能障害2010
- Author(s)
  高田芙友子、道具伸也、小原昂上、松本純一、西奥剛、山内淳史、首藤英樹、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 肥満および耐糖能異常を呈したマウスにおける血液脳関門機能障害2010
- Author(s)
  高田芙友子、道具伸也、小原昂士、松本純一、西奥剛、山内淳史、首藤英樹、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 脳ペリサイトのMMP-9産生における活性酸素種の役割2010
- Author(s)
  松本光輔、道具伸也、高田芙友子、松本純一、一木奈津子、峠沙也香、宮地晴樹、西奥剛、首藤英樹、山内淳史、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 脳ペリサイトのMMP-9産生における活性酸素種の役割2010
- Author(s)
  松本光輔、道具伸也、高田芙友子、松本純一、一木奈津子、峠沙也香、宮地晴樹、西奥剛、首藤英樹、山内淳史、片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] Activated protein C inhibits TNF-α induced MMP-9 production in the brain pericytes.2009
- Author(s)
  Takata F, Dohgu S, Wakigawa T, Harada E, Matsumoto K, Nishioku T, Yamauchi A, Kataoka Y.
- Organizer
  8^<th> cerebral vascular biology international conference
- Place of Presentation
  Sendai, Japan
- Year and Date
  2009-07-01
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] TNF-α stimulates MMP-9 secretion in the brain pericytes by activating ERK1/2, JNK and PI3 kinase signaling pathway2009
- Author(s)
  Takata F, Dohgu S, Wakigawa T, Matsumoto J, Harada E, Matsumoto K, Yamauchi A., Kataoka Y.
- Organizer
  12^<th> international symposium signaling at blood-brain and blood-retinal barrier
- Place of Presentation
  University College London
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] TNF-astimulates MMP-9 secretion in the brain pericytes by activating ERK1/2, JNK and PI3 kinase signaling pathway.2009
- Author(s)
  Takata F, Dohgu S, Wakigawa T, Matsumoto J, Harada E, Matsumoto K, Yamauchi A, Kataoka Y.
- Organizer
  12^<th> international symposium signaling at blood-brain and blood-retinal barrier
- Place of Presentation
  University College London, United Kingdam
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] Activated protein C inhibits TNF-α induced MMP-9 production in the brain pericytes2009
- Author(s)
  Takata F, Dohgu S, Wakigawa T, Harada E, Matsumoto K, Nishioku T, Yamauchi A, Kataoka Y.
- Organizer
  8^<th> cerebral vascular biology international conference
- Place of Presentation
  Sendai Excel Hotel Tokyu
- Year and Date
  2009-07-01
- Data Source
  KAKENHI-PROJECT-21790102
[Presentation] 慢性閉塞性肺疾患モデルマウスにおける血液脳関門機能脆弱化にはアンギオテンシンIIが関与する
- Author(s)
  冨永宏治、田中千亜紀、松本亜佑美、松本純一、山内淳史、二神幸次郎、片岡泰文
- Organizer
  日本薬学会第13４年会
- Place of Presentation
  熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-24590228
[]
[]

1. YAMAUCHI Astushi (90341453)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. TAKATA Fuyuko (70412575)

# of Collaborated Projects: 3 results

# of Collaborated Products: 42 results
3. DOHGU Shinya (60399186)

# of Collaborated Projects: 3 results

# of Collaborated Products: 44 results
4. KATAOKA Yasufumi (70136513)

# of Collaborated Projects: 2 results

# of Collaborated Products: 35 results
5. Matsumoto Taichi (80570803)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
6. MACHIDA Takashi (30586144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. TOMINAGA Koji (10509623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 中川慎介 (10404211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 寺田一樹 (00724197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 青木光希子 (80469379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 自見至郎 (30226360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 渡辺拓也 (90509647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMANO Yoshihisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 泉川公一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 角田俊之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 串間尚子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUMOTO Junichi 松本 純一

Matsumoto Junichi 松本 純一

Research Projects

Research Products

Co-Researchers

アンドロゲンシグナルを軸としたCOPD全身性併存症の病態解明と包括的治療戦略の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

慢性閉塞性肺疾患COPD併存うつ病の治療薬による原疾患増悪ジレンマのメカニズム

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アンドロゲンシグナルから捉えるCOPD病態の解析と治療薬の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アンドロゲンを核とする内分泌系－肺－脳の臓器連関異常化によるCOPD病態増悪機構

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Invovlvement of increased vascular permeability in bortezomib-induced lung toxicity

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Involvement of activated brain pericytes induced by inflammatory bowel disease in the increased aggregation of alpha-synuclein in the brain.

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Decreased expression of OATP2a1 in porcine pancreas elastase-induced COPD mouse model.Principal Investigator

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Blood-brain barrier function change in the chronic obstructive pulmonary disease and protective effect of the renin-angiotensin system inhibitors

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Involvement of pericytes-derived cyclophilin A in the development of insulin resistanse in the brain

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Involvement of brain pericytes in the development of obesity

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[Journal Article] Dynamic Changes of Behavioral Despair, HPA Axis Activity, and Hippocampal Neurogenesis in Male Rats Induced by Social Defeat Stress.2023

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[Journal Article] Association of T cell infiltration and morphological change of thymus gland with the aggravation of pulmonary emphysema in testosterone deficiency2023

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[Journal Article] Aging decreases docosahexaenoic acid transport across the blood-brain barrier in C57BL/6J mice2023

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MATSUMOTO Junichi 松本純一

Matsumoto Junichi 松本純一