Ueno Keigo 上野圭吾

Researcher Number	10550220
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所真菌部, 主任研究員
Affiliation (based on the past Project Information) *help	2016 – 2023: 国立感染症研究所, 真菌部, 主任研究官 2016: 国立感染症研究所, 真菌部第三室, 主任研究官 2015: 国立感染症研究所, その他部局等, 主任研究官
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / Bacteriology (including mycology) Except Principal Investigator Infectious disease medicine
Keywords	Principal Investigator クリプトコックス症 / Cryptococcus gattii / CD11b / 顆粒球 / ワクチン / Vaccine / Th17 / neutrophils / vaccine / Tissue Resident Memory … More / cryptococcosis / lung CD8 TRM / 経鼻弱毒生ワクチン / 肺常在性記憶CD8 T細胞 / CD4+ TRMs / 免疫回避 / 抗原認識 / 肉芽腫形成 / 好酸球 / 肺真菌症 / protective Th2 / 肺常在性記憶型T細胞 / 経鼻ワクチン / 肺常在性記憶Th2細胞 / lung CD4 TRM / Th2 / 多核巨細胞 / 肉芽腫 / 肺常在性記憶T細胞 / memory Th17 / iBLAT / Tissue-resident memory / IL-17A / tissue resident memory / Intranasal vaccine / Memory Th17 cells / Lung-resident T cells / iBALT / Th17細胞 / 好中球 / メモリーT細胞 / Fungal infection / granuloma / cytokine / fungal infection / CD4+ Memory T cells … More Except Principal Investigator 薬学 / 内科 / S-ニトロソ化蛋白 / 抗真菌薬 / 真菌 / 感染症 Less

肺常在性記憶CD8+ T細胞は、次世代型クリプトコックス症ワクチンの開発に有用か？Principal Investigator
- Principal Investigator
  
  上野圭吾
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  National Institute of Infectious Diseases
Lung resident memory Th2 cells amealiorates pulmonary cryptococcosis caused by Cryptococcus gattiiPrincipal Investigator
- Principal Investigator
  
  Ueno Keigo
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  National Institute of Infectious Diseases
Functional analysis and its aplication on lung-resident memory Th17 cellsPrincipal Investigator
- Principal Investigator
  
  KEIGO UENO
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  National Institute of Infectious Diseases
Dendritic cell-based systemic vaccination induces lung resident memory Th17 that contributes to long-term protection against pulmonary fungal infectionPrincipal Investigator
- Principal Investigator
  
  Ueno Keigo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  National Institute of Infectious Diseases
Development of new treatment against invasive fungal infection by S-nitrosated protein
- Principal Investigator
  
  Kinjo Yuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Infectious disease medicine
- Research Institution
  National Institute of Infectious Diseases

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Inbred SJL mice recapitulate human resistance to Cryptococcus infection due to differential immune activation2023
- Author(s)
 Davis M. J.、Martin R. E.、Pinheiro G. M.、Hoke E. S.、Moyer S.、Ueno K.、Rodriguez-Gil J. L.、Mallett M. A.、Khillan J. S.、Pavan W. J.、Chang Y. C.、Kwon-Chung K. J.
- Journal Title
 
 mBio
 
 Volume: 14 Issue: 5
- DOI
 10.1128/mbio.02123-23
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-20K07507
[Journal Article] Cryptococcus neoformans requires the TVF1 gene for thermotolerance and virulence2023
- Author(s)
 Ueno Keigo、Nagamori Akiko、Honkyu Nahoko Oniyama、Kataoka Michiyo、Shimizu Kiminori、Chang Yun C、Kwon-Chung Kyung J、Miyazaki Yoshitsugu
- Journal Title
 
 Medical Mycology
 
 Volume: 61 Issue: 10
- DOI
 10.1093/mmy/myad101
- Peer Reviewed / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-23K06536
[Journal Article] Detrimental impact of the IL-33/ST2 axis in an animal infection model with Cryptococcus neoformans2023
- Author(s)
 Ueno Keigo、Miyazaki Yoshitsugu
- Journal Title
 
 Allergol. Int.
 
 Volume: 72 Issue: 4 Pages: 530-536
- DOI
 10.1016/j.alit.2023.07.002
- ISSN
 1323-8930, 1440-1592
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-20K07507
[Journal Article] Promising whole‐cell vaccines against cryptococcosis2023
- Author(s)
  Ueno Keigo、Tsuge Soichiro、Shimizu Kiminori、Miyazaki Yoshitsugu
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 67 Issue: 5 Pages: 211-223
- DOI
  10.1111/1348-0421.13056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07507, KAKENHI-PROJECT-23K06536
[Journal Article] Cryptococcus gattii evades CD11b‐mediated fungal recognition by coating itself with capsular polysaccharides2021
- Author(s)
  Ueno Keigo、Otani Yoshiko、Yanagihara Nao、Urai Makoto、Nagamori Akiko、Sato‐Fukushima Miyuki、Shimizu Kiminori、Saito Noriko、Miyazaki Yoshitsugu
- Journal Title
  
  European Journal of Immunology
  
  Volume: x Issue: 9 Pages: 2281-2295
- DOI
  10.1002/eji.202049042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07507, KAKENHI-PROJECT-17K18385, KAKENHI-PROJECT-20K05735
[Journal Article] Vaccines and Protective Immune Memory against Cryptococcosis2020
- Author(s)
  Ueno Keigo、Yanagihara Nao、Shimizu Kiminori、Miyazaki Yoshitsugu
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 2 Pages: 230-239
- DOI
  10.1248/bpb.b19-00841
- NAID
  130007793786
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18385
[Journal Article] Neutrophil-mediated antifungal activity against highly virulent Cryptococcus gattii strain R2652019
- Author(s)
  Ueno Keigo、Yanagihara Nao、Otani Yoshiko、Shimizu Kiminori、Kinjo Yuki、Miyazaki Yoshitsugu
- Journal Title
  
  Medical Mycology
  
  Volume: 印刷中 Issue: 8 Pages: 1046-1054
- DOI
  10.1093/mmy/myy153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10040, KAKENHI-PROJECT-17K18385, KAKENHI-PROJECT-16H05349
[Journal Article] Cryptococcus gattii alters immunostimulatory potential in response to the environment2019
- Author(s)
  Ueno Keigo、Otani Yoshiko、Yanagihara Nao、Nakamura Takumi、Shimizu Kiminori、Yamagoe Satoshi、Miyazaki Yoshitsugu
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 8 Pages: 265-276
- DOI
  10.1371/journal.pone.0220989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18385, KAKENHI-ORGANIZER-17H06391
[Journal Article] Identification of a Novel Variant Form of Aspergillus fumigatus CalC and Generation of Anti-CalC Monoclonal Antibodies2019
- Author(s)
 Takatsuka Shogo、Inukai Tatsuya、Kawakubo Shun、Umeyama Takashi、Abe Masahiro、Ueno Keigo、Hoshino Yasutaka、Kinjo Yuki、Miyazaki Yoshitsugu、Yamagoe Satoshi
- Journal Title
 
 Medical Mycology Journal
 
 Volume: 60 Issue: 1 Pages: 11-16
- DOI
 10.3314/mmj.18-00013
- NAID
 130007605409
- ISSN
 2185-6486, 2186-165X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-17K10040, KAKENHI-PROJECT-17K18385, KAKENHI-PROJECT-16K09954
[Journal Article] A dendritic cell-based systemic vaccine induces long-lived lung-resident memory Th17 cells and ameliorates pulmonary mycosis2018
- Author(s)
  Ueno Keigo、Urai Makoto、Sadamoto Sota、Shinozaki Minoru、Takatsuka Shogo、Abe Masahiro、Otani Yoshiko、Yanagihara Nao、Shimizu Kiminori、Iwakura Yoichiro、Shibuya Kazutoshi、Miyazaki Yoshitsugu、Kinjo Yuki
- Journal Title
  
  Mucosal Immunology
  
  Volume: 12 Issue: 1 Pages: 265-276
- DOI
  10.1038/s41385-018-0094-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18385, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16H05349, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-17K10040
[Journal Article] Differences in Ocular Complications Between Candida albicans and Non-albicans Candida Infection Analyzed by Epidemiology and a Mouse Ocular Candidiasis Model2018
- Author(s)
  Abe Masahiro、Kinjo Yuki、Ueno Keigo、Takatsuka Shogo、Nakamura Shigeki、Ogura Sho、Kimura Muneyoshi、Araoka Hideki、Sadamoto Sota、Shinozaki Minoru、Shibuya Kazutoshi、Yoneyama Akiko、Kaku Mitsuo、Miyazaki Yoshitsugu
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 9 Pages: 1266-1266
- DOI
  10.3389/fmicb.2018.02477
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10040, KAKENHI-PROJECT-18K19529, KAKENHI-PROJECT-17K18385
[Journal Article] Mouse LIMR3/CD300f is a negative regulator of the antimicrobial activity of neutrophils2018
- Author(s)
  Ueno Keigo、Urai Makoto、Izawa Kumi、Otani Yoshiko、Yanagihara Nao、Kataoka Michiyo、Takatsuka Shogo、Abe Masahiro、Hasegawa Hideki、Shimizu Kiminori、Kitamura Toshio、Kitaura Jiro、Miyazaki Yoshitsugu、Kinjo Yuki
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 17406-17406
- DOI
  10.1038/s41598-018-35699-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19529, KAKENHI-PROJECT-17K18385, KAKENHI-PROJECT-17H04217, KAKENHI-PROJECT-17K16352
[Journal Article] Functions of CD1d-Restricted Invariant Natural Killer T Cells in Antimicrobial Immunity and Potential Applications for Infection Control2018
- Author(s)
  Kinjo Yuki、Takatsuka Shogo、Kitano Naoki、Kawakubo Shun、Abe Masahiro、Ueno Keigo、Miyazaki Yoshitsugu
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 1266-1266
- DOI
  10.3389/fimmu.2018.01266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18385, KAKENHI-PROJECT-16H05349
[Journal Article] Disrupting ceramide-CD300f interaction prevents septic peritonitis by stimulating neutrophil recruitment.2017
- Author(s)
  Izawa K, Maehara A, Isobe M, Yasuda Y, Urai M, Hoshino Y, Ueno K, Matsukawa T, Takahashi M, Kaitani A, Shiba E, Takamori A, Uchida S, Uchida K, Maeda K, Nakano N, Yamanishi Y, Oki T, Voehringer D, Roers A, Nakae S, Ishikawa J, Kinjo Y, Shimizu T, Ogawa H, Okumura K, Kitamura T, Kitaura J
- Journal Title
  
  Sci Rep.
  
  Volume: 7(1) Issue: 1 Pages: 4298-4298
- DOI
  10.1038/s41598-017-04647-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16352, KAKENHI-PROJECT-17K18385, KAKENHI-PROJECT-16H05349, KAKENHI-PROJECT-15K09784, KAKENHI-PROJECT-15K20969, KAKENHI-PUBLICLY-17H05515, KAKENHI-PROJECT-17H04217
[Journal Article] Immunization with Antigen-Pulsed Dendritic Cells Against Highly Virulent Cryptococcus gattii Infection: Analysis of Cytokine-Producing T Cells2017
- Author(s)
  Ueno K, Urai M, Takatsuka S, Abe M, Miyazaki Y, and Kinjo Y
- Journal Title
  
  Methods Mol Biol.
  
  Volume: nd
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21644
[Journal Article] Intraspecies variation in the efficacy of adjunctive recombinant interferon-γ therapy against cryptococcal meningoencephalitis in mice.2017
- Author(s)
  Ikeda-Dantsuji Y, Nakamura S, Ohno H, Inukai T, Nagi M, Ueno K, Umeyama T, Kinjo Y, Yamagoe S, Shibuya K, Miyazaki Y
- Journal Title
  
  Medical mycology
  
  Volume: 56 Issue: 3 Pages: 382-386
- DOI
  10.1093/mmy/myx063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18385, KAKENHI-PROJECT-17K10030, KAKENHI-PROJECT-17K10040
[Journal Article] Immunization with Antigen-Pulsed Dendritic Cells Against Highly Virulent Cryptococcus gattii Infection: Analysis of Cytokine-Producing T Cells2017
- Author(s)
  Ueno Keigo、Urai Makoto、Takatsuka Shogo、Abe Masahiro、Miyazaki Yoshitsugu、Kinjo Yuki
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1625 Pages: 327-339
- DOI
  10.1007/978-1-4939-7104-6_22
- ISBN
  9781493971039, 9781493971046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10040, KAKENHI-PROJECT-17K18385, KAKENHI-PROJECT-16H05349
[Journal Article] クリプトコックス症の菌種による病態の違いと治療戦略2016
- Author(s)
  中村茂樹, 上野圭吾, 宮﨑義継
- Journal Title
  
  化学療法の領域
  
  Volume: 32 Pages: 1352-1359
- Data Source
  KAKENHI-PROJECT-15K21644
[Journal Article] クリプトコックス症の診断と治療2016
- Author(s)
  宮﨑義継, 中村茂樹, 壇辻百合香, 福田惠子, 梅山隆, 浦井誠, 上野圭吾, 金城雄樹
- Journal Title
  
  呼吸器内科
  
  Volume: 30 Pages: 204-206
- Data Source
  KAKENHI-PROJECT-15K21644
[Journal Article] Evasion of Innate Immune Responses by the Highly Virulent Cryptococcus gattii by Altering Capsule Glucuronoxylomannan Structure2016
- Author(s)
  Urai M, Kaneko Y, Ueno K, Okubo Y, Aizawa T, Fukazawa H, Sugita T, Ohno H, Shibuya K, Kinjo Y and Miyazaki Y
- Journal Title
  
  Front Cell Infect Microbiol
  
  Volume: 5 Pages: 101-101
- DOI
  10.3389/fcimb.2015.00101
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15383, KAKENHI-PROJECT-26860774, KAKENHI-PROJECT-25461526, KAKENHI-PROJECT-15K21644
[Journal Article] Dendritic Cell-Based Vaccine Against Fungal Infection2016
- Author(s)
  Ueno K, Urai M, Ohkouchi K, Miyazaki Y, Kinjo Y.
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1403 Pages: 537-4
- DOI
  10.1007/978-1-4939-3387-7_30
- ISBN
  9781493933853, 9781493933877
- Data Source
  KAKENHI-PROJECT-15K15383, KAKENHI-PROJECT-16H05349, KAKENHI-PROJECT-15K21644
[Journal Article] Interferon-γ promotes phagocytosis of Cryptococcus neoformans but not Cryptococcus gattii by murine macrophages2015
- Author(s)
  Ikeda-Dantsuji Y, Ohno H, Tanabe K, Umeyama T, Ueno K, Nagi M, Yamagoe S, Kinjo Y, Miyazaki Y
- Journal Title
  
  J Infect Chemother
  
  Volume: 21 Issue: 12 Pages: 831-836
- DOI
  10.1016/j.jiac.2015.08.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15383, KAKENHI-PROJECT-26860296, KAKENHI-PROJECT-25461526
[Journal Article] 侵襲性カンジダ感染症の発症,炎症反応および薬剤耐性に関する基盤的研究2015
- Author(s)
  金城雄樹, 田辺公一, 上野圭吾, 北野尚樹, 名木　稔, 浦井誠, 星野泰隆, 梅山　隆, 山越智, 宮﨑義継
- Journal Title
  
  化学療法の領域
  
  Volume: 31 Pages: 113-119
- Data Source
  KAKENHI-PROJECT-15K15383
[Presentation] Lung resident memory Th2 cells induce multinucleated giant cells that can engulf live cryptococcal cells without opsonization2024
- Author(s)
  Keigo Ueno, Yoshitsugu Miyazaki
- Organizer
  The 10th Global Network Forum on Infection and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] 肺常在性記憶Th2細胞 lung TRM2のCryptococcus gattiiに対する感染制御機構2023
- Author(s)
 上野圭吾, 宮﨑義継
- Organizer
 第67回日本医真菌学会総会
- Data Source
 KAKENHI-PROJECT-20K07507
[Presentation] Two intranasal vaccines against Cryptococcus gattii induce protective lung resident memory Th2 cells2023
- Author(s)
  Keigo Ueno , Yoshitsugu Miyazaki
- Organizer
  The 9th Global Network Forum on Infection and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] 病原性酵母クリプトコックスの感染戦略とその分子機構: 基礎研究に立脚した感染研でのワクチン開発2023
- Author(s)
  上野圭吾
- Organizer
  第24回酵母合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K06536
[Presentation] Vaccine-inducing lung resident memory Th2 cells protect against lethal pulmonary cryptococcosis2023
- Author(s)
  Keigo Ueno, Yoshitsugu Miyazaki
- Organizer
  The 21st Awaji International Forum on Infection and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] 高病原性クリプトコックスに対する肺常在性記憶Th2細胞は多核巨細胞を誘導する2023
- Author(s)
  上野圭吾, 宮﨑義継
- Organizer
  第96回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] Vaccine-inducing lung resident CD4+ memory T cells are protective against Cryptococcus gattii infections.2022
- Author(s)
  Keigo Ueno , Kiminori Shimizu , Yun Chang , June Kwon-Chung , Yoshitsugu Miyazaki
- Organizer
  21st Congress of the International Society for Human and Animal Mycology (ISHAM)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] 高病原性クリプトコックス症に対する獲得免疫とワクチンの研究: 米国NIHへの留学を経験して2022
- Author(s)
  上野圭吾, 宮﨑義継
- Organizer
  第95回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] クリプトコックス症に対するワクチンの基盤研究: 感染制御に寄与する獲得免疫の新知見2021
- Author(s)
  上野圭吾, 宮﨑義継
- Organizer
  第65回日本医真菌学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] Cryptococcus gattiiは莢膜による抗原被覆作用でCD11bによる菌体認識を回避する2021
- Author(s)
  上野圭吾, 清水公徳, 山越智, 宮﨑義継
- Organizer
  第65回日本医真菌学会
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] クリプトコックス症ワクチンの基盤研究から見えてきた肺常在性記憶型T細胞の重要性2021
- Author(s)
  上野圭吾, 宮﨑義継
- Organizer
  第70回日本感染症学会東日本地方会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] 肺常在性記憶型T細胞による高病原性クリプトコックス症の制御2020
- Author(s)
  上野圭吾, 山越智, 宮﨑義継
- Organizer
  第94回日本感染症学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] クリプトコックス症に対する新規経鼻ワクチンの開発とその作用機構: 免疫賦活性に優れたワクチン株の作製2020
- Author(s)
  上野圭吾,柳原尚,清水公徳,山越智,宮﨑義継
- Organizer
  第93回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] Development of the novel intranasal vaccine against the highly virulent pulmonary mycoses2020
- Author(s)
  Keigo Ueno
- Organizer
  The 8th Global Network Forum on Infection and Immunity
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 肺常在性記憶型T細胞による高病原性クリプトコックス症の制御2020
- Author(s)
  上野圭吾, 山越智, 宮﨑義継
- Organizer
  第94回日本感染症学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 高病原性クリプトコックス症に対するワクチン開発とその生体防御機構について2020
- Author(s)
  上野圭吾, 宮﨑義継
- Organizer
  第64回日本医真菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 高病原性クリプトコックス症に対するワクチン開発とその生体防御機構について2020
- Author(s)
  上野圭吾, 宮﨑義継
- Organizer
  第64回日本医真菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07507
[Presentation] 高病原性クリプトコックス症に対する新規経鼻ワクチン―免疫賦活作用を増強したワクチン株の作製―2019
- Author(s)
  上野圭吾,柳原尚,清水公徳,山越智,宮﨑義継
- Organizer
  第63回日本医真菌学会総会
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] Cryptococcus gattiiの病原性に莢膜は必要か？: 環境適応と免疫回避機構における莢膜合成の意義2019
- Author(s)
  上野圭吾,大谷淑子,柳原尚,山越智,宮﨑義継
- Organizer
  真菌症フォーラム2019
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] Cryptococcus gattiiによるクリプトコックス症 ―基礎研究における最新の話題―2018
- Author(s)
 上野圭吾, 大谷淑子, 柳原尚, 清水公徳, 定本聡太, 篠崎稔, 澁谷和俊, 金城雄樹, 宮﨑義継
- Organizer
 第62回日本医真菌学会総会
- Invited
- Data Source
 KAKENHI-PROJECT-17K18385
[Presentation] A dendritic cell based systemic vaccine induces long lived lung resident memory Th17 cells and ameliorates pulmonary cryptococcosis.2018
- Author(s)
  Keigo Ueno
- Organizer
  7th Global Network Forum on Infection and Immunity
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 高病原性クリプトコックス症に対する樹状細胞ワクチン (肺常在性記憶型Th17細胞による感染制御機構について)2018
- Author(s)
  上野圭吾, 浦井誠, 定本聡太, 篠崎稔, 大谷淑子, 柳原尚, 髙塚翔吾, 阿部雅広, 林崎浩史, 清水公徳, 澁谷和俊, 宮﨑義継, 金城雄樹
- Organizer
  第29回日本生体防御学会総会
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 病原性真菌Cryptococcus gattiiの莢膜多糖による抗原被覆作用2018
- Author(s)
 大谷淑子, 上野圭吾, 柳原尚, 清水公徳, 宮﨑義継, 金城雄樹
- Organizer
 第62回日本医真菌学会総会
- Data Source
 KAKENHI-PROJECT-17K18385
[Presentation] 病原性真菌Cryptococcus gattiiの自然免疫回避機構: 莢膜多糖による抗原被覆作用について2018
- Author(s)
 上野圭吾, 金城雄樹, 宮﨑義継
- Organizer
 第92回日本感染症学会総会
- Data Source
 KAKENHI-PROJECT-17K18385
[Presentation] 好中球による高病原性真菌Cryptococcus gattiiに対する殺菌機構2018
- Author(s)
 柳原尚, 上野圭吾, 大谷淑子, 清水公徳, 宮﨑義継, 金城雄樹
- Organizer
 第62回日本医真菌学会総会
- Data Source
 KAKENHI-PROJECT-17K18385
[Presentation] 高病原性クリプトコックス症に対するワクチンとその感染制御作用2018
- Author(s)
  上野圭吾, 定本聡太, 篠崎稔, 大谷淑子, 柳原尚, 阿部雅広, 清水公徳, 澁谷和俊, 宮﨑義継, 金城雄樹
- Organizer
  第62回日本医真菌学会総会
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 高病原性真菌Cryptococcus gattiiの環境適応と免疫回避における莢膜合成の生理的意義2017
- Author(s)
  大谷淑子, 上野圭吾, 浦井誠, 清水公徳, 片岡紀代, 齋藤典子, 宮崎義継, 金城雄樹
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-20
- Data Source
  KAKENHI-PROJECT-15K21644
[Presentation] 好中球は高病原性真菌Cryptococcus gattii の増殖を抑制するか?2017
- Author(s)
  上野圭吾, 柳原尚, 大谷淑子, 清水公徳, 宮崎義継, 金城雄樹
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] クリプトコックスの莢膜欠損株は何故病原性が低いのか？: 環境適応と免疫回避機構における莢膜合成の意義2017
- Author(s)
  上野圭吾, 金城雄樹, 浦井誠, 宮﨑義継
- Organizer
  第91回日本感染症学会総会
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 病原性真菌クリプトコックスの病原性の解析とその応用: ワクチン開発から新規記憶型T細胞の同定まで2017
- Author(s)
  上野圭吾, 浦井誠, 大谷淑子, 阿部雅広, 髙塚翔吾, 清水公徳, 片岡紀代, 齋藤典子, 宮﨑義継, 金城雄樹
- Organizer
  第9回日本細菌学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K21644
[Presentation] 病原性真菌Cryptococcus gattii の新規感染機構: 莢膜多糖による抗原被覆作用につ2017
- Author(s)
  大谷淑子, 上野圭吾, 柳原尚, 浦井誠, 清水公徳, 宮崎義継, 金城雄樹
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] Dendritic cell-based vaccination induces lung resident memory Th17 cells that ameliorate pulmonary infection with highly virulent Cryptococcus gattii2017
- Author(s)
  Keigo Ueno, Shogo Takatsuka and Yuki Kinjo
- Organizer
  第46回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 肺常在性記憶型Th17細胞は、高病原性肺クリプトコックス症を制御する2017
- Author(s)
  上野圭吾, 金城雄樹, 定本聡太, 篠崎稔, 阿部雅広, 澁谷和俊, 宮﨑義継
- Organizer
  第61回日本医真菌学会総会
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 高病原性クリプトコックス症に対する生体防御機構: 肺常在性記憶型Th17細胞の役割について2017
- Author(s)
  上野圭吾, 金城雄樹, 浦井誠, 髙塚翔吾, 阿部雅広, 大谷淑子, 定本聡太, 篠崎稔, 澁谷和俊, 宮﨑義継
- Organizer
  第23回真菌症フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 樹状細胞ワクチンによる肺常在性記憶型Th17細胞の誘導: 高病原性クリプトコックス症をモデルとして2017
- Author(s)
  上野圭吾, 浦井誠, 髙塚翔吾, 阿部雅広, 大谷淑子, 清水公徳, 宮﨑義継, 金城雄樹
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-15K21644
[Presentation] 肺常在性記憶型Th17細胞による難治性肺真菌症の感染制御 (高病原性クリプトコックス症をモデルとして)2017
- Author(s)
  上野圭吾, 浦井誠, 定本聡太, 篠崎稔, 大谷淑子, 髙塚翔吾, 阿部雅広, 清水公徳, 澁谷和俊, 宮﨑義継, 金城雄樹
- Organizer
  第28回日本生体防御学会総会
- Data Source
  KAKENHI-PROJECT-17K18385
[Presentation] 肺真菌症に対する樹状細胞ワクチン: 肺で誘導される記憶型T細胞の解析2016
- Author(s)
  上野圭吾, 金子幸弘, 金城雄樹
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15K21644
[Presentation] Dendritic cell-based systemic vaccination induces lung resident memory Th17 that contributes to long-term protection against pulmonary fungal infection2016
- Author(s)
  Keigo Ueno, Shogo Takatsuka, and Yuki Kinjo
- Organizer
  The 45th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  沖縄
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-15K21644
[Presentation] 肺常在性記憶型T細胞は高病原性クリプトコックス症の感染制御に寄与するか？2016
- Author(s)
  上野圭吾, 金城雄樹, 浦井誠, 栃木直文, 篠崎稔, 清水公徳, 亀井克彦, 大野秀明, 二木芳人, 澁谷和俊, 宮﨑義継
- Organizer
  第60回日本医真菌学会総会
- Place of Presentation
  東京
- Year and Date
  2016-10-01
- Data Source
  KAKENHI-PROJECT-15K21644
[Presentation] 肺クリプトコックス症に対する樹状細胞ワクチン: 感染制御効果の持続性に関する検討-2016
- Author(s)
  上野圭吾, 金城雄樹, 浦井誠, 金子幸弘, 亀井克彦, 大野秀明, 二木芳人, 澁谷和俊, 宮﨑義継
- Organizer
  第90回日本感染症学会総会
- Place of Presentation
  東京
- Year and Date
  2016-04-15
- Data Source
  KAKENHI-PROJECT-15K21644
[Presentation] 病原性真菌Cryptococcus gattiiに対する樹状細胞ワクチン -ワクチンが誘導する肺常在性CD4+記憶型T細胞は感染制御に寄与するか？-2016
- Author(s)
  上野圭吾, 浦井誠, 栃木直文, 篠崎稔, 高塚翔吾, 澁谷和俊, 宮﨑義継, 金城雄樹
- Organizer
  第27回日本生体防御学会総会
- Place of Presentation
  福岡
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-15K21644
[Presentation] 病原性真菌Cryptococcus gattiiに対する樹状細胞ワクチンとその感染制御作用ーワクチンで誘導されるTh1/Th17応答と多核巨細胞の形成についてー2015
- Author(s)
  上野圭吾, 浦井誠, 水口裕紀, 大河内香代, 宮﨑義継, 金城雄樹
- Organizer
  第26回日本生体防御学会総会
- Place of Presentation
  東京
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-15K21644
[Presentation] 樹状細胞ワクチンを用いた高病原性Cryptcoccus gattiiに対する感染制御機構の解析2015
- Author(s)
  上野圭吾, 金城雄樹, 浦井誠, 大久保陽一郎, 清水公徳, 金子幸弘, 亀井克彦, 大野秀明, 二木芳人, 澁谷和俊, 宮﨑義継
- Organizer
  第59回日本医真菌学会総会
- Place of Presentation
  札幌
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K21644
[Presentation] Cryptcoccus gattiiを制御する樹状細胞療法はサイトカイン産生CD4 T細胞を誘導する2015
- Author(s)
  上野圭吾, 金城雄樹, 金子幸弘, 大野秀明, 亀井克彦, 二木芳人, 宮﨑義継
- Organizer
  第63回日本化学療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-06-06
- Data Source
  KAKENHI-PROJECT-15K21644

1. Kinjo Yuki (20570831)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
2. ABE Masahiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. ISHIMA YU (00457590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 丸山徹 (90423657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. IWAKURA Yoichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SHIBUYA Kazutoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. TAKATSUKA Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. OTANI Yoshiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. SAKAI JUN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SAITOH NORIKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKATSUKA SHOGO

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. NAKAHARA MAKIKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAWAKUBO SHUN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 宮崎義継

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. 伊沢久未

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ueno Keigo 上野 圭吾

Research Projects

Research Products

Co-Researchers

肺常在性記憶CD8+ T細胞は、次世代型クリプトコックス症ワクチンの開発に有用か？Principal Investigator

Principal Investigator

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Lung resident memory Th2 cells amealiorates pulmonary cryptococcosis caused by Cryptococcus gattiiPrincipal Investigator

Principal Investigator

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Review Section

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Functional analysis and its aplication on lung-resident memory Th17 cellsPrincipal Investigator

Principal Investigator

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Dendritic cell-based systemic vaccination induces lung resident memory Th17 that contributes to long-term protection against pulmonary fungal infectionPrincipal Investigator

Principal Investigator

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Research Institution

Development of new treatment against invasive fungal infection by S-nitrosated protein

Principal Investigator

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Research Institution

[Journal Article] Inbred SJL mice recapitulate human resistance to <i>Cryptococcus</i> infection due to differential immune activation2023

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[Journal Article] <i>Cryptococcus neoformans</i> requires the <i>TVF1</i> gene for thermotolerance and virulence2023

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[Journal Article] Detrimental impact of the IL-33/ST2 axis in an animal infection model with <i>Cryptococcus neoformans</i>2023

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[Journal Article] Promising whole‐cell vaccines against cryptococcosis2023

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[Journal Article] Cryptococcus gattii evades CD11b‐mediated fungal recognition by coating itself with capsular polysaccharides2021

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[Journal Article] Vaccines and Protective Immune Memory against Cryptococcosis2020

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[Journal Article] Neutrophil-mediated antifungal activity against highly virulent Cryptococcus gattii strain R2652019

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[Journal Article] Cryptococcus gattii alters immunostimulatory potential in response to the environment2019

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Ueno Keigo 上野圭吾