FUJITA NAOKI 藤田直己

… Alternative Names

Fujita Naoki 藤田直己

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Researcher Number	10554488
Other IDs	https://orcid.org/0000-0003-2279-4553
Affiliation (Current)	2025: 東京大学, 大学院農学生命科学研究科(農学部), 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京大学, 大学院農学生命科学研究科(農学部), 助教 2016 – 2021: 東京大学, 大学院農学生命科学研究科(農学部), 特任助教 2014 – 2015: 東京大学, 農学生命科学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Veterinary medical science Except Principal Investigator Basic Section 42020:Veterinary medical science-related / Basic Section 56070:Plastic and reconstructive surgery-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Veterinary medical science
Keywords	Principal Investigator 間葉系幹細胞 / 骨髄脂肪細胞周囲細胞 / 犬 / 再生医療 / 骨・軟骨再生 / 軟骨再生医療 / 骨再生医療 / バイオプリンティング / 骨軟骨再生医療 / 肥大軟骨 … More / 軟骨内骨化 / 骨髄脂肪細胞 / マルチカラー解析 / フローサイトメトリー / ユニバーサルマーカー / 哺乳類 / リハビリテーション / 脊髄再生医療 / トレッドミルトレーニング / 血管新生因子 / メカニカルストレス / 脊髄損傷 / 肝細胞成長因子（HGF） / 脂肪細胞 / 骨髄間葉系幹細胞 / 幹細胞治療 / 骨髄脂肪 / 肝細胞成長因子 / 犬骨髄間葉系幹細胞 / 骨髄 … More Except Principal Investigator 脊髄損傷 / 間葉系幹細胞 / 犬 / 再生医療 / 脊髄再生医療 / 骨髄脂肪細胞周囲細胞 / 静脈投与 / 肝細胞成長因子 / 国際共同研究 / 異分野共同研究 / 移植医療 / 機能再建 / 複合組織移植 / 脊髄再生 / 再生治療 / 細胞外小胞 / イヌ / 徐放 / エクソソーム / 結紮後発作症候群 / 生体内組織形成術（iBTA) / 門脈体循環シャント / 肝細胞成長因子（HGF） / 角膜損傷 / 角膜上皮シート / 角膜再生医療 / 犬角膜上皮細胞 / 角膜再生 / 角膜上皮細胞 / リン酸化ニューロフィラメント重鎖（pNF-H) / バイオマーカー / 病期分類 / 骨髄脂肪細胞周囲細胞（BM-PAC) / 慢性期 / 亜急性期 / 急性期 / 視床下部 / 体温低下 / LPS / mPGES-1 / インターフェロンγ / インターフェロンガンマ / PGE2 / プロスタグランジン / エストロゲン / 低体温 / In vivo イメージング / 骨髄間葉系幹細胞 / 生体内イメージング Less

Creation and pathological analysis of acquired portosystemic shunt model using in-vivo tissue architecture.
- Principal Investigator
  
  藤田淳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
Collaborative research for novel vascularized composite transplantation
- Principal Investigator
  
  荒木淳
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Shizuoka Cancer Center Research Institute
Development of osteochondral regenerative medicine by reproducing endochondral ossification using hypertrophic cartilage differentiation ability of canine mesenchymal stem cellsPrincipal Investigator
- Principal Investigator
  
  藤田直己
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
間葉系幹細胞エクソソームを用いた治療の基盤技術の開発と脊髄再生誘導への応用
- Principal Investigator
  
  西田英高
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Azabu University
Quantitative evaluation of pathological changes after spinal cord injury based on time course blood concentration of phosphorylated neurofilament heavy chain.
- Principal Investigator
  
  藤原玲奈
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
Combined grafts of corneal epithelial cell sheets and HGF secreting cell sheets for treatment of canine corneal injury
- Principal Investigator
  
  都築圭子
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
Exploration of novel mammalian mesenchymal stem cells in bone marrow and their universal markersPrincipal Investigator
- Principal Investigator
  
  藤田直己
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  The University of Tokyo
Staging-based regenerative therapy for spinal cord injury in dogs
- Principal Investigator
  
  Ryohei Nishimura
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
Integration of regenetive therapy and rehabilitation for spinal cord injury in dogs based on mechanical stressPrincipal Investigator
- Principal Investigator
  
  Fujita Naoki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
Analysis of central thermoregulatory system using mice with estrus stage-depending infectious hypothermia
- Principal Investigator
  
  Matsuwaki Takashi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
Establishment of regenerative therapy for dogs using delivery system of hepatocyte growth factor secreted from novel canine mesenchymal stem cells
- Principal Investigator
  
  Nishimura Ryohei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  The University of Tokyo
Characterization of canine novel mesenchymal stem cells adhering to adipocytes in bone marrow for clinical application in regenerative therapy.Principal Investigator
- Principal Investigator
  
  Fujita Naoki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  The University of Tokyo

All 2024 2023 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Canine bone marrow peri-adipocyte cells could therapeutically benefit acute spinal cord injury through migration and secretion of hepatocyte growth factor to inflammatory milieu2023
- Author(s)
  Chen J, Fujita N, Takeda T, Hanyu W, Takatani H, Nakagawa T, Nishimura R.
- Journal Title
  
  Exp. Anim.
  
  Volume: 72 Issue: 1 Pages: 19-29
- DOI
  10.1538/expanim.22-0026
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03123
[Journal Article] Mechanical regulation underlies effects of exercise on serotonin-induced signaling in the prefrontal cortex neurons.2020
- Author(s)
  Ryu Y, Maekawa T, Yoshino D, Sakitani N, Takashima A, Inoue T, Suzurikawa J, Toyohara J, Tago T, Fujita N, Sawada K, Murase S, Watanave M, Sakai T, Yoshikawa Y, Ogata T, Shinohara M, Nagao M, Sawada Y
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 2 Pages: 100874-100874
- DOI
  10.1016/j.isci.2020.100874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0018, KAKENHI-PROJECT-18K07658, KAKENHI-PLANNED-17H06380, KAKENHI-PROJECT-18H04088, KAKENHI-PROJECT-18H02027, KAKENHI-PROJECT-19H03124, KAKENHI-PROJECT-18K15655
[Journal Article] Effect of fibroblast growth factor-2 and serum on canine mesenchymal stem cell chondrogenesis2018
- Author(s)
  Endo Kentaro、Fujita Naoki、Nakagawa Takayuki、Nishimura Ryohei
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: 印刷中 Issue: 11-12 Pages: 901-910
- DOI
  10.1089/ten.tea.2018.0177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05037, KAKENHI-PROJECT-16J08547
[Journal Article] Isolation and Characterization of Multipotent Mesenchymal Stem Cells Adhering to Adipocytes in Canine Bone Marrow2017
- Author(s)
  Lin Hsing-Yi, Fujita Naoki, Endo Kentaro, Morita Maresuke, Takeda Tae, Nakagawa Takayuki, and Nishimura Ryohei
- Journal Title
  
  Stem Cells and Development
  
  Volume: 26 Issue: 6 Pages: 431-440
- DOI
  10.1089/scd.2016.0200
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26850192, KAKENHI-PROJECT-16H05037
[Presentation] Anorectal transplantation: the first long-term success in a canine model2024
- Author(s)
  Jun ARAKI, Yuji NISHIZAWA, Naoki FUJITA, Kaori FUKUSHIGE, Yasuto AKIYAMA, Kana SANO, Flavio GALVAO, Munekazu NAITO
- Organizer
  12th ERC Meeting & 34th EURAPS Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27759
[Presentation] Anorectal Transplantation: International Collaboration Research for Stoma Patients2024
- Author(s)
  Jun ARAKI, Yuji NISHIZAWA, Naoki FUJITA, Kaori FUKUSHIGE, Yasuto AKIYAMA, Kana SANO, Flavio GALVAO, Munekazu NAITO
- Organizer
  16th Congress of the European Federation of Societies for Microsurgery
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27759
[Presentation] 犬の新規骨髄間葉系幹細胞（BM-PACs)の神経細胞分化誘導2019
- Author(s)
  羽生航、藤田直己、陳君妍、武田妙、遠藤建太郎、中川貴之、西村亮平
- Organizer
  第18回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] Development of regenerative therapy for spinal cord injury in dogs.2019
- Author(s)
  Hanyu W, Fujita N, Chen J, Takeda T, Nishimura R
- Organizer
  Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03123
[Presentation] 急性期脊髄損傷モデルを用いた犬間葉系幹細胞の経静脈移植効果の検討2019
- Author(s)
  陳君妍、藤田直己、羽生航、武田妙、遠藤健太郎、中川貴之、西村亮平
- Organizer
  第18回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] The therapeutic effects and homing ability of intravenous administration of allogeneic canine mesenchymal stem cells2019
- Author(s)
  Chen J, Fujita N, Takeda T, Hanyu Y, Nakagawa T, Nishimura R
- Organizer
  2019Congress of Asian Society of Veterinary Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03123
[Presentation] 犬間葉系幹細胞のHoming機能と血管新生効果に着目した脊髄損傷に対する移植療法の開発2019
- Author(s)
  武田妙、藤田直己、羽生航、陳君妍、遠藤健太郎、中川貴之、西村亮平
- Organizer
  第18回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] バイオ３Dプリンタを用いた犬間葉系幹細胞からの軟骨組織構築における低酸素環境の影響2019
- Author(s)
  遠藤健太郎、藤田直己、國富芳博、高井治美、鳥井蓉子、武田妙、陳君研、羽生航、中川貴之、西村亮平
- Organizer
  第18回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] 塩基性線維芽細胞増殖因子が犬間葉系幹細胞の未分化性の維持・獲得に与える影響2018
- Author(s)
  大田拓也、遠藤健太郎、武田妙、陳君妍、羽生航、藤田直己、中川貴之、西村亮平
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] Intravenous transplantation of Canine mesenchymal stem cells for mice acute spinal cord2018
- Author(s)
  J. Chen, N. Fujita, T. Takeda, K. Endo, W. Hanyu, T. Nakagawa, R. Nishimura
- Organizer
  8th Annual Congress of Asian Society of Veterinary Surgery
- Invited
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] FGF-2 enhances multipotency of canine mesenchymal stem cells through maintenance of undifferentiated state2018
- Author(s)
  W. Hanyu, N. Fujita, J. Chen, T. Takeda, K. Endo,T. Nakagawa, R. Nishimura
- Organizer
  8th Annual Congress of Asian Society of Veterinary Surgery
- Invited
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] Challenges to develop stem cell therapy in dogs using novel mesenchymal stem cells isolated from bone marrow.2018
- Author(s)
  Naoki Fujita
- Organizer
  TERMIS WC 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] 犬の骨髄脂肪細胞周囲細胞の肝細胞成長因子分泌能と脊髄損傷に対する経静脈移移植の効果2018
- Author(s)
  武田妙、陳君妍、藤田直己、遠藤健太郎、中川貴之、西村亮平
- Organizer
  第17回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] Homing ability and angiogenesis effect of canine mesenchymal stem cell has therapeutic effect on sub-acute spinal cord injury2018
- Author(s)
  Tae Takeda, Junjien Chen, Kentaro Endo, Wataru Hanyu, Naoki Fujita, Takayuki Nakagawa, Ryohei Nishimura
- Organizer
  8th Annual Congress of Asian Society of Veterinary Surgery
- Invited
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] 低酸素環境による犬間葉系幹細胞の硝子軟骨への分化運命決定2018
- Author(s)
  遠藤健太郎、藤田直己、武田妙、陳君妍、羽生航、中川貴之、西村亮平
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] 低酸素環境が犬間葉系幹細胞の軟骨分化に与える影響2018
- Author(s)
  遠藤健太郎、藤田直己、武田妙、陳君妍、中川貴之、西村亮平
- Organizer
  第17回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] 亜急性期脊髄損傷に対し経静脈移植した犬間葉系幹細胞の走化性と移植効果2018
- Author(s)
  武田妙、藤田直己、陳君妍、遠藤健太郎、羽生航、中川貴之、西村亮平
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] 犬の骨髄から分離・培養した新規間葉系幹細胞BM-PACsの性状と再生医療への応用2018
- Author(s)
  藤田直己
- Organizer
  第17回日本再生医療学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] 犬間葉系幹細胞の効率的な軟骨分化条件の検討2017
- Author(s)
  遠藤健太郎, 藤田直己, 林杏怡、中川貴之, 西村亮平
- Organizer
  第16回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] Transplantation of canine bone marrow peri-adipocyte cells for acute spinal cord injury in mice.2017
- Author(s)
  林杏怡、藤田直己、遠藤健太郎、中川貴之、西村亮平
- Organizer
  第16回日本再生医療学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-26850192
[Presentation] 3D Bioprinting of Cartilage Tissue Using Canine Mesenchymal Stem Cell Spheroids under the Optimal Growth Factor Condition2017
- Author(s)
  Kentaro Endo, Naoki Fujita, Yoshihiro Kunitomi, Tae Takeda, Junyan Chen, Koichi Nakayama,Ryohei Nishimura
- Organizer
  TERMIS Americas 2017 Annual Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] 急性期脊髄損傷に対する犬新規間葉系幹細胞移植の治療効果2017
- Author(s)
  藤田直己、林杏怡、遠藤健太郎、武田妙、陳君妍、中川貴之、西村亮平
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] 間葉系幹細胞の効率的な軟骨分化条件の検討2017
- Author(s)
  遠藤健太郎、藤田直己、林杏怡、中川貴之、西村亮平
- Organizer
  第16回日本再生医療学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-26850192
[Presentation] Transplantation of canine bone marrow peri-adipocyte cells for acute spinal cord injury in mice.2017
- Author(s)
  林杏怡、藤田直己、遠藤健太郎、中川貴之、西村亮平
- Organizer
  第16回日本再生医療学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] Transplantation of canine bone marrow peri-adipocyte cells for acute spinal cord injury in mice2017
- Author(s)
  HXING-YI LIN, NAOKI FUJITA, KENTARO ENDO, TAKAYUKI NAKAGAWA, RYOHEI NISHIMURA
- Organizer
  第16回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H05037
[Presentation] TNF-α and IL-1β induce hepatocyte growth factor secretion by canine bone marrow peri-adipocyte cells2016
- Author(s)
  林杏怡、藤田直己、遠藤健太郎、中川貴之、西村亮平
- Organizer
  日本再生医療学会
- Place of Presentation
  大阪
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PROJECT-26850192
[Presentation] Ceilinf culture of adipose layer isolated from canine bone marrow can generate promising mesenchymal stem cells for regenerative medicine2015
- Author(s)
  Lin Xing-Yi, Naoki Fujita, Kentaro Endo, Takayuki Nakagawa, Ryohei Nishimura
- Organizer
  sian Meeting of. Animal Medical Specialtie
- Place of Presentation
  Kuala Lumpur, Malaysia
- Year and Date
  2015-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26850192
[Presentation] Ceiling　culture　of　adipose　lyaer　isolated　from　canine　bone　marrow　can　generate　promising　mesenchymal stem cells for regenrative therapy
- Author(s)
  Lin HY, Endo K, Fujita N, Nakagwa R, Nishimura R
- Organizer
  Asian Meeting of Veterinary Surgery
- Place of Presentation
  大阪
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-26850192

1. Nishimura Ryohei (80172708)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
2. 西田英高 (00622804)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 山本貴恵 (50806362)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Matsuwaki Takashi (20447361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 藤澤彩乃 (10624885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 伊藤大介 (40508694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大松勉 (60455392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 藤原玲奈 (60456176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 都築圭子 (30364251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 馬渕洋 (50424172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 藤田淳 (00554487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 中山泰秀 (50250262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 田畑泰彦 (50211371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 枝村一弥 (80366624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 荒木淳 (00508088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 福重香 (30805023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. 西澤祐吏 (50545001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 秋山靖人 (70222552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 佐野加奈 (90899858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. Itaka Keiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 篠原正浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJITA NAOKI 藤田 直己

Fujita Naoki 藤田 直己

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Development of osteochondral regenerative medicine by reproducing endochondral ossification using hypertrophic cartilage differentiation ability of canine mesenchymal stem cellsPrincipal Investigator

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Exploration of novel mammalian mesenchymal stem cells in bone marrow and their universal markersPrincipal Investigator

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Integration of regenetive therapy and rehabilitation for spinal cord injury in dogs based on mechanical stressPrincipal Investigator

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Characterization of canine novel mesenchymal stem cells adhering to adipocytes in bone marrow for clinical application in regenerative therapy.Principal Investigator

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[Journal Article] Canine bone marrow peri-adipocyte cells could therapeutically benefit acute spinal cord injury through migration and secretion of hepatocyte growth factor to inflammatory milieu2023

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[Journal Article] Mechanical regulation underlies effects of exercise on serotonin-induced signaling in the prefrontal cortex neurons.2020

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FUJITA NAOKI 藤田直己

Fujita Naoki 藤田直己