TATSUKAWA HIDEKI 辰川英樹

… Alternative Names

Tatsukawa Hideki 辰川英樹

TATSUKAWA Hideki 辰川英樹

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Researcher Number	10565253
Other IDs
Affiliation (Current)	2025: 名古屋大学, 創薬科学研究科, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 名古屋大学, 創薬科学研究科, 助教 2014 – 2021: 名古屋大学, 創薬科学研究科, 助教 2012: 名古屋大学, 創薬科学研究科, 助教 2010 – 2011: 独立行政法人理化学研究所, 分子リガンド生物研究チーム, 特別研究員
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 38060:Applied molecular and cellular biology-related / Basic Section 53040:Nephrology-related / General pharmacology
Keywords	Principal Investigator トランスグルタミナーゼ / 線維化 / タンパク質架橋酵素 / 架橋酵素 / タンパク質架橋化酵素 / 肝硬変 / 肝線維化 / デコイペプチド / コラーゲン / 線維芽細胞 … More / 細胞外マトリクス / 細胞外基質 / プロテオミクス / 架橋修飾 / 細胞死 / 上皮間葉転換 / 尿細管上皮細胞 / 腎線維化 / 肝臓 / 抗線維化薬 / 質量分析 / 基質探索 / 架橋 / サイトケラチン / Cytokeratin-18 / ALDH2 / サイトケラチン18 / タンパク質架橋化酵 / レチノイド受容体 / スクリーニング / レチノイド核内受容体 / リン酸化 / 肝癌細胞 / 非環式レチノイド / ケミカルバイオロジー / 生理活性物質 / 核内受容体 / アポトーシス / 抗癌剤 / レチノイド / 癌 Less

Comprehensive elucidation and regulation of cross-linked residues involved in fibrosisPrincipal Investigator
- Principal Investigator
  
  辰川英樹
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Nagoya University
Role of protein cross-linking modifications in regulating epithelial mesenchymal transition in renal tubulePrincipal Investigator
- Principal Investigator
  
  Tatsukawa Hideki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Nagoya University
Global identification of the substrates of protein crosslinking enzyme and the development of preventive drug in tissue fibrosisPrincipal Investigator
- Principal Investigator
  
  TATSUKAWA Hideki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
Analysis of mechanism and development of regulation approach in liver fibrosis via transglutaminasePrincipal Investigator
- Principal Investigator
  
  Tatsukawa Hideki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
Development of novel cancer drug based on pathway analysis for specific cell death of hepatocellular carcinoma treated with acyclic retinoidPrincipal Investigator
- Principal Investigator
  
  TATSUKAWA Hideki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
  The Institute of Physical and Chemical Research

All 2023 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] もっとよくわかる！線維化と疾患2023
- Author(s)
  辰川英樹、人見清隆（5. 細胞外マトリクス項目の執筆分担）
- Total Pages
  172
- Publisher
  羊土社
- ISBN
  9784758122139
- Data Source
  KAKENHI-PROJECT-23K26866
[Book] 食品・バイオにおける最新の酵素利用　井上國世　監修2019
- Author(s)
  手島裕文、加藤まなみ、辰川英樹、人見清隆
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-19K08675
[Book] 組織の線維化に伴い架橋される基質タンパク質群の網羅的同定・解析2017
- Author(s)
  辰川英樹、人見清隆
- Total Pages
  10
- Publisher
  日本応用酵素協会
- Data Source
  KAKENHI-PROJECT-16K09353
[Book] Transglutaminase：Multiple Functional Modifiers and Targets for New Drug Discovery - Preferred Substrate Structure of Transglutaminases.2016
- Author(s)
  Hitomi K and Tatsukawa H.
- Total Pages
  20
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26860500
[Journal Article] Inhibition of Transglutaminase 2 Reduces Peritoneal Injury in a Chlorhexidine-Induced Peritoneal Fibrosis Model2023
- Author(s)
  Kunoki S, Tatsukawa H, Sakai Y, Kinashi H, Kariya T, Suzuki Y, Mizuno M, Yamaguchi M, Sasakura H, Ikeno M, Takeuchi K, Ishimoto T, Hitomi K, Ito Y
- Journal Title
  
  Laboratory Investigation
  
  Volume: 103 Issue: 4 Pages: 100050-100050
- DOI
  10.1016/j.labinv.2022.100050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07289, KAKENHI-PROJECT-21H02817, KAKENHI-PROJECT-19K07761, KAKENHI-PROJECT-19K11728, KAKENHI-PROJECT-21K08275, KAKENHI-PUBLICLY-21H00442, KAKENHI-PROJECT-22K08309, KAKENHI-PROJECT-22K19590, KAKENHI-PUBLICLY-22H04786, KAKENHI-PROJECT-23K26866
[Journal Article] Development of peptide-based biosensors for detecting cross-linking and deamidation activities of transglutaminases2023
- Author(s)
  Tatsukawa Hideki、Aoyama Ruriko、Hitomi Kiyotaka
- Journal Title
  
  Amino Acids
  
  Volume: 55 Issue: 6 Pages: 807-819
- DOI
  10.1007/s00726-023-03272-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20568, KAKENHI-PROJECT-23K26866
[Journal Article] Tissue transglutaminase exacerbates renal fibrosis via alternative activation of monocyte-derived macrophages2023
- Author(s)
  Shinoda Yoshiki、Tatsukawa Hideki、Yonaga Atsushi、Wakita Ryosuke、Takeuchi Taishu、Tsuji Tokuji、Tanaka Miyako、Suganami Takayoshi、Hitomi Kiyotaka
- Journal Title
  
  Cell Death & Disease
  
  Volume: 14 Issue: 2 Pages: 136-136
- DOI
  10.1038/s41419-023-05622-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08526, KAKENHI-PROJECT-20H03447, KAKENHI-PROJECT-22K19524, KAKENHI-PUBLICLY-22H04806, KAKENHI-PROJECT-23K26866
[Journal Article] Novel function of transglutaminase 2 in extracellular histone-induced acute lung injury2023
- Author(s)
  Mizuno Tomohiro、Nagano Fumihiko、Ito Yoshimasa、Tatsukawa Hideki、Shinoda Yoshiki、Takeuchi Taishu、Takahashi Kazuo、Tsuboi Naotake、Nagamatsu Tadashi、Yamada Shuhei、Maruyama Shoichi、Hitomi Kiyotaka
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 678 Pages: 179-185
- DOI
  10.1016/j.bbrc.2023.08.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20568, KAKENHI-PROJECT-23K26829, KAKENHI-PROJECT-23K26866
[Journal Article] Role of Transglutaminase 2 in Cell Death, Survival, and Fibrosis.2021
- Author(s)
  Tatsukawa H, Hitomi K.
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 7 Pages: 1842-1842
- DOI
  10.3390/cells10071842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08675, KAKENHI-PROJECT-20K20568
[Journal Article] 臓器の線維化を誘導するタンパク質架橋酵素の網羅的な分子標的解析2021
- Author(s)
  辰川英樹、人見清隆
- Journal Title
  
  B&I バイオサイエンスとインダストリー
  
  Volume: 80 Pages: 113-117
- Data Source
  KAKENHI-PROJECT-19K08675
[Journal Article] Spatially Resolved Identification of Transglutaminase Substrates by Proteomics in Pulmonary Fibrosis.2021
- Author(s)
  Takeuchi T, Tatsukawa H, Shinoda Y, Kuwata K, Nishiga M, Takahashi H, Hase N, Hitomi K.
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 65 Issue: 3 Pages: 319-330
- DOI
  10.1165/rcmb.2021-0012oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08675, KAKENHI-PROJECT-20K20568
[Journal Article] Thrombin-deficient mutant of medaka, a model fish, displays serious retardation in blood coagulation.2021
- Author(s)
  Watanabe Y., Oguri R., Suzuki R., Ishikawa Y., Tatsukawa H., Hashimoto H., Hitomi K.
- Journal Title
  
  Biosceince, Biochemistry and Biotechnology
  
  Volume: 85 Issue: 4 Pages: 824-833
- DOI
  10.1093/bbb/zbaa098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02134, KAKENHI-PROJECT-19K08675, KAKENHI-PROJECT-20K20568
[Journal Article] Investigation of mouse amniotic fluid for stimulating ability of keratinocyte differentiation depending on the fetal stage.2021
- Author(s)
  Kuribayashi M, Kawaguchi Y, Teshima H, Yamaguchi H, Tatsukawa H, Hitomi K.
- Journal Title
  
  Arch Biochem Biophys
  
  Volume: 711 Pages: 109003-109003
- DOI
  10.1016/j.abb.2021.109003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08675, KAKENHI-PROJECT-21J12945, KAKENHI-PROJECT-20K20568
[Journal Article] Transglutaminase orthologues in medaka fish - biochemical characterization and establishment of gene-deficient mutants2020
- Author(s)
  Meng Qi、Watanabe Yuko、Suzuki Risa、Oguri Rina、Tatsukawa Hideki、Hitomi Kiyotaka
- Journal Title
  
  Analytical Biochemistry
  
  Volume: - Pages: 113610-113610
- DOI
  10.1016/j.ab.2020.113610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08675, KAKENHI-PROJECT-18H02134
[Journal Article] Gene disruption of medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2) causes movement retardation2020
- Author(s)
  Watanabe Yuko、Okuya Kazuho、Takada Yuki、Kinoshita Masato、Yokoi Saori、Chisada Shinichi、Kamei Yasuhiro、Tatsukawa Hideki、Yamamoto Naoyuki、Abe Hideki、Hashimoto Hisashi、Hitomi Kiyotaka
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 3 Pages: 213-222
- DOI
  10.1093/jb/mvaa038
- NAID
  40022375409
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08675, KAKENHI-PROJECT-17K19228, KAKENHI-PROJECT-19K06762, KAKENHI-PROJECT-20K06757, KAKENHI-PROJECT-20K20303, KAKENHI-PROJECT-19K16247, KAKENHI-PROJECT-18H02134, KAKENHI-PUBLICLY-19H04889
[Journal Article] Analysis of the expression of transglutaminases in the reconstructed human epidermis using a three-dimensional cell culture2020
- Author(s)
  Teshima Hirofumi、Kato Manami、Tatsukawa Hideki、Hitomi Kiyotaka
- Journal Title
  
  Analytical Biochemistry
  
  Volume: - Pages: 113606-113606
- DOI
  10.1016/j.ab.2020.113606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08675, KAKENHI-PROJECT-17K19228, KAKENHI-PROJECT-18H02134
[Journal Article] タンパク質架橋酵素を介した上皮細胞の間葉転換機構の解析2020
- Author(s)
  辰川英樹、篠田祥希、竹内大修、人見清隆
- Journal Title
  
  日本応用酵素協会誌
  
  Volume: 55 Pages: 1-10
- Data Source
  KAKENHI-PROJECT-19K08675
[Journal Article] Identification and characterization of substrates crosslinked by transglutaminases in liver and kidney fibrosis2020
- Author(s)
  Tatsukawa Hideki、Takeuchi Taishu、Shinoda Yoshiki、Hitomi Kiyotaka
- Journal Title
  
  Analytical Biochemistry
  
  Volume: - Pages: 113629-113629
- DOI
  10.1016/j.ab.2020.113629
- NAID
  120006941034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08675, KAKENHI-PROJECT-18H02134
[Journal Article] Studies on differentiation-dependent expression and activity of distinct transglutaminases by specific substrate peptides using three dimensional reconstituted epidermis.2019
- Author(s)
  Ｔａｎａｂｅ　Ｙ．，　Ｙａｍａｎｅ　Ｍ，　Ｋａｔｏ　Ｍ．，　Ｔｅｓｈｉｍａ　Ｈ．，　Ｋｕｒｉｂａｙａｓｈｉ　Ｍ．，　Ｔａｔｓｕｋａｗａ　Ｈ．，　Ｔａｋａｍａ　Ｈ．，　Ａｋｉｙａｍａ　Ｍ．，　　Ｈｉｔｏｍｉ　Ｋ．
- Journal Title
  
  FEBS J.
  
  Volume: in press Issue: 13 Pages: 2536-2548
- DOI
  10.1111/febs.14832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19228, KAKENHI-PROJECT-16K09353, KAKENHI-PROJECT-19K08675, KAKENHI-PROJECT-18K19540, KAKENHI-PROJECT-18H02134, KAKENHI-PROJECT-18H02832
[Journal Article] Higher susceptibility to osmolality of the medaka (Oryzias latipes) mutants in orthologue genes of mammalian skin transglutaminases2018
- Author(s)
  Watanabe Yuko、Furukawa Eri、Tatsukawa Hideki、Hashimoto Hisashi、Kamei Yasuhiro、Taniguchi Yoshihito、Hitomi Kiyotaka
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 未定 Issue: 7 Pages: 1-4
- DOI
  10.1080/09168451.2018.1453294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09353
[Journal Article] Tschimganine and its derivatives extend the chronological life span of yeast via activation of the Sty1 pathway2018
- Author(s)
  Hibi Takahide、Ohtsuka Hokuto、Shimasaki Takafumi、Inui Shougo、Shibuya Masatoshi、Tatsukawa Hideki、Kanie Kei、Yamamoto Yoshihiko、Aiba Hirofumi
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 8 Pages: 620-637
- DOI
  10.1111/gtc.12604
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07662, KAKENHI-PROJECT-17K19227, KAKENHI-PROJECT-16K09353, KAKENHI-PROJECT-17H03792
[Journal Article] Detection and identification of potential transglutaminase 2 substrates in the mouse renal glomeruli.2018
- Author(s)
  Ｉｔｏ　Ｙ．，　Ｔａｔｓｕｋａｗａ　Ｈ．，　Ｙａｍａｇｕｃｈｉ　Ｈ．，　Ｔａｋａｈａｓｈｉ　Ｋ．，　Ｈｉｔｏｍｉ　Ｋ．，　ａｎｄ　Ｙｕｓｚａｗａ　Ｙ．
- Journal Title
  
  Arch. Biochem. Biophys.
  
  Volume: 660 Pages: 11-19
- DOI
  10.1016/j.abb.2018.10.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19228, KAKENHI-PROJECT-18H02134, KAKENHI-PROJECT-16K09353, KAKENHI-PROJECT-16K09632
[Journal Article] Isozyme-specific comprehensive characterization of transglutaminase-crosslinked substrates in kidney fibrosis2018
- Author(s)
  Tatsukawa Hideki、Otsu Risa、Tani Yuji、Wakita Ryosuke、Hitomi Kiyotaka
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 7306-7306
- DOI
  10.1038/s41598-018-25674-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09353, KAKENHI-PROJECT-17K19228, KAKENHI-PROJECT-18H02134
[Journal Article] Prevention of hepatocellular carcinoma by targeting MYCN-positive liver cancer stem cells with acyclic retinoid2018
- Author(s)
  Qin XY, Suzuki H, Honda M, Okada H, Kaneko S, Inoue I, Ebisui E, Hashimoto K, Carninci P, Kanki K, Tatsukawa H, Ishibashi N, Masaki T, Matsuura T, Kagechika H, Toriguchi K, Hatano E, Shirakami Y, Shiota G, Shimizu M, Moriwaki H, Kojima S
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 115 Issue: 19 Pages: 4969-4974
- DOI
  10.1073/pnas.1802279115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09035, KAKENHI-PROJECT-16K19378, KAKENHI-PROJECT-18K06976, KAKENHI-PROJECT-18K15833, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-16K09352, KAKENHI-PROJECT-16K09353, KAKENHI-PROJECT-17K15933
[Journal Article] Targeting transglutaminase 2 partially restores extracellular matrix structure but not alveolar architecture in experimental bronchopulmonary dysplasia.2018
- Author(s)
  ＭｉｚｉｋｏＶａ　Ｉ，　Ｐｆｅｆｆｅｒ　Ｔ，　Ｎａｒｄｉｅｌｌｏ　Ｃ，　Ｓｕｒａｔｅ　Ｓｏｌａｌｉｇｕｅ　ＤＥ，　Ｓｔｅｅｎｂｏｃｋ　Ｈ，　Ｔａｔｓｕｋａｗａ　Ｈ，　Ｓｉｌｖａ　ＤＭ，　Ｈｉｔｏｍｉ　Ｋ，　Ｍｏｒｔｙ　ＲＥ．他６名
- Journal Title
  
  FEBS J.
  
  Volume: 285 Issue: 16 Pages: 3056-3076
- DOI
  10.1111/febs.14596
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19228, KAKENHI-PROJECT-18H02134, KAKENHI-PROJECT-16K09353
[Journal Article] Characterization of medaka orthologue of human transglutaminase 2 (OlTGT)2017
- Author(s)
  Takada Y., Watanabe Y., Okuya K., Tatsukawa H., Hashimoto H, Hitomi K.
- Journal Title
  
  Biochem. Biotechnol. Biosci.
  
  Volume: 81 Issue: 3 Pages: 469-474
- DOI
  10.1080/09168451.2016.1256757
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292192, KAKENHI-PROJECT-26440121, KAKENHI-PROJECT-16K09353
[Journal Article] Biochemical characterization of a medaka (Oryzias latipes) orthologue for mammalian Factor XIII and establishment of a gene-edited mutant2017
- Author(s)
  Horimizu Rima、Ogawa Ryota、Watanabe Yuko、Tatsukawa Hideki、Kinoshita Masato、Hashimoto Hisashi、Hitomi Kiyotaka
- Journal Title
  
  The FEBS Journal
  
  Volume: 284 Issue: 17 Pages: 2843-2855
- DOI
  10.1111/febs.14153
- NAID
  120006473527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09353
[Journal Article] Global identification and analysis of isozyme-specific possible substrates crosslinked by transglutaminases using their substrate peptides in mouse liver fibrosis.2017
- Author(s)
  Tatsukawa H., Tan Y., Otsu R., Nakagawa H., Hitomi K
- Journal Title
  
  Sci. rep
  
  Volume: 22 Issue: 1 Pages: 45049-45049
- DOI
  10.1038/srep45049
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292192, KAKENHI-PROJECT-16K09353
[Journal Article] FRET-based detection of isozyme-specific activities of transglutaminases.2017
- Author(s)
  Tatsukwa H, Liu H, Oba S, Kamiya N, Nakanishi Y, Hitomi K
- Journal Title
  
  Amino Acids
  
  Volume: 49 Issue: 3 Pages: 615-623
- DOI
  10.1007/s00726-016-2322-0
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26292192, KAKENHI-PROJECT-16K09353
[Journal Article] Distribution of transglutaminase family members in mouse whole body sections.2015
- Author(s)
  Tatsukawa H, Abe N, Ohashi S, Hitomi K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 467 Issue: 4 Pages: 1046-51
- DOI
  10.1016/j.bbrc.2015.10.001
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860500, KAKENHI-PROJECT-26292192
[Journal Article] Biochemical Characterization of Medaka (Oryzias latipes) Transglutaminases, OlTGK1 and OlTGK2, as Orthologues of Human Keratinocyte-Type Transglutaminase.2015
- Author(s)
  Kikuta A, Furukawa E, Ogawa R, Suganuma N, Saitoh M, Nishimaki T, Katsumura T, Oota H, Kawamoto T, Tatsukawa H, Hashimoto H, Hitomi K.
- Journal Title
  
  PLoS One.
  
  Volume: 10 Issue: 12 Pages: 1-13
- DOI
  10.1371/journal.pone.0144194
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860500, KAKENHI-PROJECT-26292192
[Journal Article] Early response as shown by enhancement of transglutaminase 1 expression after cisplatin-induced acute kidney injury.2015
- Author(s)
  Furukawa K, Yamane M, Tatsukawa H, Hitomi K.
- Journal Title
  
  Arch Biochem Biophys.
  
  Volume: 586 Pages: 27-32
- DOI
  10.1016/j.abb.2015.09.021
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860500, KAKENHI-PROJECT-26292192
[Journal Article] Regulation of transglutaminasemediated hepatic cell death inalcoholic steatohepatitis and non-alcoholic steatohepatitis2012
- Author(s)
  Kojima S, Kuo TF and Tatsukawa H
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 27 Pages: 52-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790266
[Journal Article] Free fatty acids induce transglutaminase 2-dependent apoptosis in hepatocytes via ER stress-stimulated PERK pathways2012
- Author(s)
  Kuo TF, Tatsukawa H, Matsuura T, Nagatsuma K, Hirose S and Kojima S
- Journal Title
  
  J Cell Physiol
  
  Volume: 227 Pages: 1130-1137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790266
[Journal Article] New insights into the functions and localization of nuclear transglutaminase 22011
- Author(s)
  Kuo TF, Tatsukawa H and Kojima S
- Journal Title
  
  FEBS J (Review)
  
  Volume: 278 Pages: 4756-4767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790266
[Journal Article] Dual induction of caspase 3 and transglutaminasedependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells2011
- Author(s)
  Tatsukawa H, Sano T, Fukaya Y, Ishibashi N, Watanabe M, Okuno M, Moriwaki H and Kojima S
- Journal Title
  
  Mol Cancer
  
  Volume: 10 Pages: 11-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790266
[Journal Article] In situ detection of active transglutaminases for keratinocyte type (TGase 1) and tissue type (TGase 2) using fluorescence-labeled highly reactive substrate peptides2011
- Author(s)
  Itoh M, Kawamoto T, Tatsukawa H, Kojima S, Yamanishi K and Hitomi K
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 59 Pages: 180-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790266
[Journal Article] Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells.2011
- Author(s)
  Tatsukawa H., et al.
- Journal Title
  
  Mol Cancer
  
  Volume: 10
- NAID
  120006341956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790266
[Journal Article] Brain infarction correlates more closely with acrolein than with reactive oxygen species2011
- Author(s)
  Saiki R, Park H, Ishii I, Yoshida M, Nishimura K, Toida T, Tatsukawa H, Kojima S, Ikeguchi Y, Pegg AE, Kashiwagi K and Igarashi K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 404 Pages: 1044-1049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] Polarization of M2 macrophages and development of renal fibrosis are caused by transglutaminase, a protein cross-linking enzyme.2023
- Author(s)
  辰川英樹、篠田祥希、人見清隆
- Organizer
  第52回日本免疫学会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] タンパク質架橋化酵素を介した線維化促進マクロファージの活性化機構の解明2023
- Author(s)
  代永篤司、篠田祥希、辰川英樹、人見清隆
- Organizer
  日本薬学会東海支部
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 低酸素応答機構の制御によるヒト表皮立体培養系での分化促進効果2023
- Author(s)
  遠藤真悠子、手島裕文辻徳治、辰川英樹、人見清隆
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 炎症因子の発現制御に関わるタンパク質架橋化酵素トランスグルタミナーゼ１の機能解明2023
- Author(s)
  藤澤優斗、辰川英樹、人見清隆
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 上皮バリア機能に必須な架橋酵素の誘導型欠損マウスの作製と表現型解析2023
- Author(s)
  辰川英樹、人見清隆
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 腎線維化を誘導するマクロファージの極性化機構の解明2023
- Author(s)
  辰川英樹、篠田祥希、人見清隆
- Organizer
  第66回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 低酸素応答の制御を利用した進化型in vitro 表皮モデルの研究2023
- Author(s)
  遠藤真悠子、手島裕文、辻徳治、辰川英樹、人見清隆
- Organizer
  日本農芸化学会中部支部・関西支部合同大会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] タンパク質架橋化酵素が基質として架橋する分子群の同定解析2023
- Author(s)
  竹内大修、山本雪乃、辰川英樹、人見清隆
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 線維化を誘導するマクロファージの極性化に必須なタンパク質翻訳後修飾反応2023
- Author(s)
  辰川英樹、人見清隆
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 哺乳類の羊水中に存在する表皮分化促進因子の探索及び同定2023
- Author(s)
  今井陸斗、川口友、辰川英樹、辻徳治、人見清隆
- Organizer
  日本農芸化学会中部支部・関西支部合同大会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 羊水がヒト表皮細胞における表皮形成関連因子の発現制御に与える影響2023
- Author(s)
  辻徳治、小野川諒、辰川英樹、人見清隆
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 線維化に関わるマクロファージの極性化機構の解明2023
- Author(s)
  辰川英樹、篠田祥希、人見清隆
- Organizer
  第58回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] Generation and phenotype analysis of conditional knockout mice deficient in transglutaminase 1, a protein cross-linking enzyme that regulates epithelial barrier function2023
- Author(s)
  高橋淳生、辰川英樹、人見清隆
- Organizer
  JAACT2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] Cre-/loxP systemを用いた上皮組織特異的トロンビン欠損メダカの樹立と解析2023
- Author(s)
  土門龍生、Meng Qi, 高島美南、辻徳治、辰川英樹、渡邉優子、人見清隆
- Organizer
  日本農芸化学会中部支部・関西支部合同大会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 架橋酵素トランスグルタミナーゼによる細胞外マトリクスの制御2023
- Author(s)
  辰川英樹、篠田祥希、人見清隆
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 線維症の病態機構解明に向けた細胞外マトリクス定量測定系の構築2023
- Author(s)
  山本雪乃、竹内大修、辰川英樹、人見清隆
- Organizer
  日本薬学会東海支部
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 有羊膜類の羊水がヒト表皮細胞の分化関連因子の発現に与える影響の解析2023
- Author(s)
  辻徳治、小野川諒、村井篤、辰川英樹、人見清隆
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] Enzyme-regulating macrophages found in both humans and mice are essential for the development of renal fibrosis2023
- Author(s)
  辰川英樹、篠田祥希、人見清隆
- Organizer
  JSICR/MMCB2023国際学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 表皮培養系における振とう培養による分化亢進メカニズムの解明2023
- Author(s)
  遠藤真悠子、手島裕文辻徳治、辰川英樹、人見清隆
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] Involvement of hypoxia-inducible factor on air-liquid interface stimulation induced epidermal differentiation2023
- Author(s)
  手島裕文、遠藤真悠子、辻徳治、辰川英樹、人見清隆
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] 羊水によるヒト表皮細胞における表皮形成関連因子の発現制御2023
- Author(s)
  辻徳治、辰川英樹、人見清隆
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K26866
[Presentation] モデル生物としてのメダカの組織特異的誘導変異個体の作製2021
- Author(s)
  石川雄太、小栗莉奈、勝村恵理、Meng Qi、渡邉優子、辰川英樹、人見清隆
- Organizer
  日本農芸化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 架橋酵素の空間的分布に基づく肺線維化の架橋基質タンパク質の網羅的解析2021
- Author(s)
  竹内大修、辰川英樹、人見清隆
- Organizer
  日本薬学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] モデル生物としてのメダカを用いた組織特異的誘導変異個体の作製2021
- Author(s)
  石川雄太、勝村恵理、Meng QI, 辰川英樹、渡邉優子、橋本寿史、人見清隆
- Organizer
  日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] タンパク質架橋酵素トランスグルタミナーゼ１の誘導型欠損マウスの作製と表現型解析2021
- Author(s)
  田村瞭太、辰川英樹、人見清隆
- Organizer
  日本分子生物学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] タンパク質架橋化酵素を指標とするマウス胎生時期の皮膚バリア形成の解析2021
- Author(s)
  川口友輔、手島裕文、辰川英樹、人見清隆
- Organizer
  日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] タンパク質架橋酵素活性の制御剤探索に向けた新規FRETプローブの開発2021
- Author(s)
  青山瑠里子、辰川英樹、人見清隆
- Organizer
  日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 肺線維化においてタンパク質架橋化酵素により架橋される基質のプロテオミクス解析2021
- Author(s)
  竹内大修、桑田啓子、辰川英樹、人見清隆
- Organizer
  トランスグルタミナーゼ研究会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Analysis of M2 macrophage polarization regulated by ranglutaminase 2 in kidney fibrosis2021
- Author(s)
  篠田祥希、辰川英樹、人見清隆
- Organizer
  日本免疫学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Biochemical Properties and Novel Function Investigation of the Blood Coagulation Factor, Fibrinogen by Using Medaka2021
- Author(s)
  Meng Qi、石川雄太、勝村恵理、渡邉優子、辰川英樹、人見清隆
- Organizer
  27th Japanese Medaka and Zebrafish Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 尿細管障害におけるタンパク質架橋酵素の機能解析2021
- Author(s)
  丹羽優、辰川英樹、人見清隆
- Organizer
  日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] マウス羊水中に存在する表皮細胞分化制御因子の精製2021
- Author(s)
  川口友輔、栗林美樹、手島裕文、辰川英樹、人見清隆
- Organizer
  日本農芸化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 抗線維化薬ピルフェニドンの薬理作用点同定に向けた探索研究2020
- Author(s)
  竹内大修、横島聡、辰川英樹、人見清隆
- Organizer
  日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Investigation for the novel functions of fibrinogen through establishing gene-deficient medaka (Oryzias latipes)2020
- Author(s)
  Meng Qi、渡邉優子、辰川英樹、人見清隆
- Organizer
  日本分子生物学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] マクロファージの極性化に関わるタンパク質架橋化酵素の解析2020
- Author(s)
  篠田祥希、辰川英樹、人見清隆
- Organizer
  日本臨床分子医学会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 組織線維化において架橋修飾されるタンパク質群の網羅的同定解析2020
- Author(s)
  辰川英樹、竹内大修、人見清隆
- Organizer
  日本臨床分子医学会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 空気暴露が促進する表皮分化メカニズムの解析2020
- Author(s)
  手島裕文、辰川英樹、人見清隆
- Organizer
  日本分子生物学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 羊水中に存在する表皮細胞分化制御成分の性状解析2020
- Author(s)
  栗林美樹、川口友輔、手島裕文、山口、辰川英樹、人見清隆
- Organizer
  日本分子生物学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] マクロファージの極性化に関わるタンパク質架橋化酵素の解析2020
- Author(s)
  篠田祥希、辰川英樹、人見清隆
- Organizer
  日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 肺線維化においてタンパク質架橋化酵素により架橋される基質のプロテオミクス解析2020
- Author(s)
  竹内大修、桑田啓子、辰川英樹、人見清隆
- Organizer
  日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] タンパク質架橋化酵素によるマクロファージの極性化制御の解析2020
- Author(s)
  篠田祥希、辰川英樹、人見清隆
- Organizer
  日本農芸化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 血液凝固異常モデルをトロンビン遺伝子欠損メダカにより再現する2020
- Author(s)
  小栗莉奈、渡邉優子、石川雄太、Meng Qi、辰川英樹、人見清隆
- Organizer
  日本農芸化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 培養ヒト表皮細胞の分化に空気暴露が必須とされるメカニズムの解析2020
- Author(s)
  伊藤帆南、手島裕文、辰川英樹、人見清隆
- Organizer
  日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 組織線維化におけるタンパク質架橋反応の分子標的の解明研究2020
- Author(s)
  辰川英樹、篠田祥希、竹内大修、人見清隆
- Organizer
  日本生化学会大会シンポジウム
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 羊水中に存在する表皮細胞分化制御成分の性状解析2020
- Author(s)
  川口友輔、栗林美樹、手島裕文、辰川英樹、人見清隆
- Organizer
  日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] M2型マクロファージの極性化におけるトランスグルタミナーゼの機能解析2020
- Author(s)
  篠田祥希、辰川英樹、人見清隆
- Organizer
  日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 腎線維化において架橋修飾される新規基質タンパク質の同定と解析2019
- Author(s)
  辰川英樹、人見清隆
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Detection system of transglutaminase in vitro and in situ activities using specific substrate peptides in the epidermis and three-dimensional keratinocyte cultured system2019
- Author(s)
  加藤まなみ、手島裕文、田辺勇輝、辰川英樹、人見清隆
- Organizer
  Gordon Research Conferences Barrier function
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] マウスの胎生段階における表皮形成と羊水成分の変動解析2019
- Author(s)
  栗林美樹、手島裕文、加藤まなみ、辰川英樹、人見清隆
- Organizer
  日本農芸化学会関西中部合同支部例会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] ヒト表皮の分化に気相培養を必須とするメカニズムの研究2019
- Author(s)
  手島裕文、加藤まなみ、辰川英樹、人見清隆
- Organizer
  生化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 肺線維症に寄与するタンパク質架橋化酵素の役割2019
- Author(s)
  竹内大修、桑田啓子、辰川英樹、人見清隆
- Organizer
  日本農芸化学会関西中部合同支部例会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Structural and Biochemical Investigation of amostatic Factor Fibrinogen Using Medaka (Oryzias lateipes)2019
- Author(s)
  Qi Meng,、鈴木里沙、小栗莉奈、渡辺優子、辰川英樹、橋本寿史、人見清隆
- Organizer
  分子生物学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] メダカを用いた血液凝固因子トロンビンの欠損個体作製による機能解析2019
- Author(s)
  鈴木里沙、 Meng,、Qi 、渡辺優子、辰川英樹、橋本寿史、人見清隆
- Organizer
  ゼブラフィッシュ・メダカ創薬研究会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Analysis of the mechanism of transglutaminase-mediated tissue fibrosis2019
- Author(s)
  辰川英樹、竹内大修、人見清隆
- Organizer
  Gordon Research Conferences Tissue Repair and Regeneration
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 表皮立体培養細胞系を用いたタンパク質架橋化酵素群の機能解析2019
- Author(s)
  加藤まなみ、手島裕文、栗林美樹、山口央輝、辰川英樹、人見清隆
- Organizer
  92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Investigation for Medaka Orthologues of Human Fibrinogen2019
- Author(s)
  Meng,　Qi、鈴木里沙、小栗莉奈、渡辺優子、辰川英樹、橋本寿史、人見清隆
- Organizer
  小型魚類研究会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] マウスの胎生段階における表皮形成と羊水成分の変動解析胎生進行に伴う表皮形成レベルと羊水成分の変動解析2019
- Author(s)
  栗林美樹、手島裕文、山口央輝、辰川英樹、人見清隆
- Organizer
  分子生物学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 胚線維化におけるタンパク質架橋化酵素の病態生理学的意義の解析2019
- Author(s)
  竹内大修、辰川英樹、人見清隆
- Organizer
  92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Studies on epidermal differentiation by air-liquid interface stimulation in three-dimensional culture2019
- Author(s)
  手島裕文、栗林美樹、辰川英樹、人見清隆
- Organizer
  日本研究皮膚科学会年次学術大会・総会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 表皮細胞分化に気相培養を必須とするメカニズムの解析2019
- Author(s)
  手島裕文、栗林美樹、伊藤帆南、加藤まなみ辰川英樹、人見清隆
- Organizer
  分子生物学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] タンパク質の架橋による翻訳後修飾反応を介した組織線維化の分子メカニズムの解析2019
- Author(s)
  辰川英樹、人見清隆
- Organizer
  92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Biochemical characterization of medaka thrombin, a blood coagulation factor, and establishment of its gene-deficient fish2019
- Author(s)
  小栗莉奈、鈴木里沙、Meng　Qi、小栗莉奈、渡辺優子、辰川英樹、橋本寿史、人見清隆
- Organizer
  小型魚類研究会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Studies on cellular changes upon air-liquid phase stimulation in the three-dimensional keratinocyte culture system2019
- Author(s)
  手島裕文、栗林美樹、伊藤帆南、辰川英樹、人見清隆
- Organizer
  Gordon Research Conferences Barrier function
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] Establishment of Fibrinogen Knockout Medaka (Oryzias latipes) Aiming to Investigate itsNovel Function and Drug Screening2019
- Author(s)
  Qi Meng,、鈴木里沙、小栗莉奈、渡辺優子、辰川英樹、橋本寿史、人見清隆
- Organizer
  ゼブラフィッシュ・メダカ創薬研究会
- Data Source
  KAKENHI-PROJECT-19K08675
[Presentation] 肝線維症において架橋される新規基質タンパク質の解析2018
- Author(s)
  中川晴加、辰川英樹、人見清隆
- Organizer
  農芸化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] メダカのタンパク質架橋酵素群の機能解析と疾患モデルとしての変異体2018
- Author(s)
  渡邉優子、鈴木里沙、Meng Qi, 辰川英樹、人見清隆
- Organizer
  第４回ゼブラフィッシュメダカ創薬研究会
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] 腎糸球体におけるタンパク質架橋接着酵素 (Transglutaminase 2) の基質候補探索と同定2018
- Author(s)
  伊藤辰将、辰川英樹、山口央輝、高橋和男、人見清隆、湯澤由紀夫
- Organizer
  第9回分子腎臓フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] 腎疾患に関わる組織型トランスグルタミナーゼ基質候補タンパク質の探索と同定2018
- Author(s)
  伊藤辰将、辰川英樹、山口央輝、高橋和男、人見清隆、湯澤由紀夫
- Organizer
  トランスグルタミナーゼ研究会
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] Global Identification of Crosslinked Potential Tissue Transglutaminase Substrates in the Mouse Glomeruli2018
- Author(s)
  伊藤辰将、辰川英樹、山口央輝、高橋和男、人見清隆、湯澤由紀夫
- Organizer
  第43回日本医療マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] モデル生物としてのメダカを用いた組織型タンパク質架橋化酵素の機能解析2018
- Author(s)
  渡邉優子、鈴木里沙、Meng Qi、辰川英樹、人見清隆
- Organizer
  農芸化学会大会
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] Immunochemical characterization of medaka orthologues for human thrombin.2018
- Author(s)
  鈴木里沙、辰川英樹、人見清隆
- Organizer
  小型魚類研究会 24th Japanese medaka and zebrafish meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] モデル生物メダカのトランスグルタミナーゼ（TG2）変異体の行動遅延2018
- Author(s)
  渡邉優子、奥谷冬穂、辰川英樹、橋本寿史、人見清隆
- Organizer
  トランスグルタミナーゼ研究会
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] 最終分化に空気暴露を必須とするヒト表皮立体培養細胞の性状解析2018
- Author(s)
  手島裕文、栗林美樹、辰川英樹、人見清隆
- Organizer
  農芸化学会大会
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] Isozyme-specific identification and characterization of substrates crosslinked by transglutaminases in liver fibrosis.2018
- Author(s)
  辰川英樹、人見清隆
- Organizer
  The 13th International Symposium on ALPD and Cirrhosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] Detection and Identification of Possible Transglutaminase Substrates in the Mouse Renal Glomeruli.2018
- Author(s)
  Ito Y, Tatsukawa H, Yamaguchi H, Takahashi K, Hitomi K, Yuzawa Y
- Organizer
  Gordon Research Conference on Transglutaminases in Human Disease Processes (ゴードン国際会議)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] 腎線維化において活性化するタンパク質架橋化酵素の役割りと基質タンパク質群の網羅的同定・解析2018
- Author(s)
  辰川英樹、人見清隆
- Organizer
  第9回分子腎臓フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] 糸球体におけるタンパク質架橋化酵素（Transglutaminase 2）の機能解明に向けた基質探索2018
- Author(s)
  伊藤辰将、辰川英樹、山口央輝、高橋和男、人見清隆、湯澤由紀夫
- Organizer
  第42回IgA腎症研究会
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] Isozyme-Specific Global Identification and Analysis of Transglutaminase Substrates in Fibrotic Diseases.2018
- Author(s)
  Tatsukawa H
- Organizer
  Gordon Research Conference on Transglutaminases in Human Disease Processes (ゴードン国際会議)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] 肝線維化において架橋されるタンパク質群の網羅的同定法の確立および基質タンパク質の解析2017
- Author(s)
  辰川英樹、人見清隆
- Organizer
  生命科学系学会合同年次大会 ConBio2017
- Invited
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] 組織線維化におけるタンパク質架橋化酵素の役割2017
- Author(s)
  辰川英樹，大津里紗，脇田崚資，人見清隆
- Organizer
  日本生化学会中部支部第81回例会
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] Global identification and analysis of isozyme-specific substrates crosslinked by transglutaminases in mouse liver fibrosis2017
- Author(s)
  Hideki Tatsukawa, Haruka Nakagawa, Kiyotaka Hitomi
- Organizer
  American Association for the Study of Liver Diseases (AASLD) - The liver meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] 腎線維化に伴い架橋される新規基質タンパク質 S100-A8およびS100-A9 の機能解析2016
- Author(s)
  脇田崚資、大津里紗、辰川英樹、人見清隆
- Organizer
  日本生化学会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] Comprehensive approach to identification and analysis of crosslinked substrate in liver fibrosis.2016
- Author(s)
  Tatsukawa H, Tani Y, Hitomi K
- Organizer
  Gordon Research Conference; Transglutaminase in Human Disease Processes
- Place of Presentation
  Girona, Spain
- Year and Date
  2016-07-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] 肝線維化に伴い架橋される基質タンパク質の網羅的同定および解析2016
- Author(s)
  辰川英樹、大津里紗、谷優治、人見清隆
- Organizer
  日本生化学会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] Identification and characterization of crosslinked substrates by transglutaminases in renal fibrosis.2016
- Author(s)
  Wakita R, Otsu R, Tatsukawa H, Hitomi K
- Organizer
  Gordon Research Conference; Transglutaminase in Human Disease Processes
- Place of Presentation
  Girona, Spain
- Year and Date
  2016-07-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09353
[Presentation] 腎臓の線維化進行に伴うタンパク質架橋化修飾の役割2015
- Author(s)
  大津里紗、谷優治、脇田峻資、辰川英樹、人見清隆
- Organizer
  2015年度日本農芸化学会中部・関西支部合同大会
- Place of Presentation
  富山県立大学
- Year and Date
  2015-09-19
- Data Source
  KAKENHI-PROJECT-26860500
[Presentation] 腎線維化組織において架橋修飾されるタンパク質群の網羅的解析2015
- Author(s)
  大津里紗、谷優治、辰川英樹、人見清隆
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26860500
[Presentation] Detections of Isozyme-specific activity and Substrate for Transglutaminase in Animal Models for Fibrotic Disease.2014
- Author(s)
  辰川英樹
- Organizer
  The 2nd Tokai Nephrology & Immunology Forum
- Place of Presentation
  名古屋
- Year and Date
  2014-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-26860500
[Presentation] 非環式レチノイドの肝細胞癌に対する選択的殺細胞作用のオミックス解析2013
- Author(s)
  秦咸陽, 辰川英樹,鈴木治和,林崎良英,魏菲菲,田之倉優,石橋直人,森脇久隆,小嶋聡一
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  新宿
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] Further analyses of nuclear localization of transglutaminase and screening of inhibitors against nuclear localization of transglutaminase2012
- Author(s)
  Tatsukawa H et al.
- Organizer
  Gordon Research Conference on Transglutaminase in Human Disease Processes
- Place of Presentation
  Davidson College, Davidson, NC
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] トランスクリプトーム解析による非環式レチノイドの肝細胞癌に対する選択的殺細胞作用の新規標的分子同定2012
- Author(s)
  秦咸陽, 辰川英樹,鈴木治和,林崎良英,吉永淳,小嶋聡一
- Organizer
  第23回日本レチノイド研究会学術集会
- Place of Presentation
  米子
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] Studies on the molecular mechanism of a selective anti-cancer effect of ACR toward HCC2012
- Author(s)
  Qin XY, Tatsukawa H, Suzuki H, Yoshinaga J, Kojima S
- Organizer
  The 7th International Symposium on Alcoholic Liver and Pancreatic Diseases and Cirrhosis (ISALPD/C)
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] Further analyses of nuclear localization of transglutaminase and screening of inhibitors against nuclear localization of transglutaminase2012
- Author(s)
  Tatsukawa H, Hitomi K and Kojima S
- Organizer
  Gordon Research Conference on Transglutaminase in Human Disease Processes
- Place of Presentation
  Davidson College, Davidson
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] 肝細胞癌再発抑制剤「非環式レチノイド」の作用標的分子同定の試み2011
- Author(s)
  辰川英樹,本田香織,近藤恭光,堂前直,石橋直人,長田裕之,森脇久隆,小嶋聡一
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] 肝細胞癌再発抑制剤「非環式レチノイド」の作用標的分子同定の試み2011
- Author(s)
  辰川英樹, ほか
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] リン酸化特異抗体の作製および非環式レチノイドの標的分子同定の試み2011
- Author(s)
  辰川英樹,清水雅仁,本田香織,近藤恭光,堂前直,石橋直人,長田裕之,森脇久隆,小嶋聡一
- Organizer
  第22回日本レチノイド研究会学術集会
- Place of Presentation
  日本大学
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] リン酸化RXR□特異抗体の作製および非環式レチノイドの標的分子同定の試み2011
- Author(s)
  辰川英樹, ほか
- Organizer
  第22回日本レチノイド研究会学術集会
- Place of Presentation
  日本大学(東京都)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] 非環式レチノイドによる肝細胞癌治療におけるリン酸化阻害作用と標的分子同定の試み2010
- Author(s)
  辰川英樹,石橋直人,森脇久隆,小嶋聡一
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  船堀
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] 非環式レチノイドによる肝細胞癌治療におけるリン酸化阻害作用と標的分子同定の試み2010
- Author(s)
  辰川英樹
- Organizer
  日本がん分子標的治療学会
- Place of Presentation
  東京都船堀
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] 非環式レチノイドによる肝癌細胞死誘導機構2010
- Author(s)
  辰川英樹
- Organizer
  BMB2010
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] 非環式レチノイドによる肝癌細胞死誘導機構2010
- Author(s)
  辰川英樹,石橋直人,森脇久隆,小嶋聡一
- Organizer
  第33回日本分子生物学会年会&第83回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790266
[Presentation] Detections of isozyme-specific activity and substrate for transglutaminase in animal models for fibrotic disease
- Author(s)
  Hideki Tatsukawa, Yuji Tani, Kiyotaka Hitomi
- Organizer
  Gordon Research Conference - Transglutaminase in Human Disease Processes
- Place of Presentation
  Barga（Italy）
- Year and Date
  2014-06-29 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26860500
[Presentation] 腎線維症の病態形成における架橋化反応の役割
- Author(s)
  辰川英樹、谷優治、人見清隆
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26860500

1. 伊藤圭祐 (40580460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 北浦靖之 (90442954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HITOMI kiyotaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
4. IKENO Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. MASAKI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 武内恒成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 大塚北斗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 橋本寿史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 田中都

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TATSUKAWA HIDEKI 辰川 英樹

Tatsukawa Hideki 辰川 英樹

TATSUKAWA Hideki 辰川 英樹

Research Projects

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Co-Researchers

Comprehensive elucidation and regulation of cross-linked residues involved in fibrosisPrincipal Investigator

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Role of protein cross-linking modifications in regulating epithelial mesenchymal transition in renal tubulePrincipal Investigator

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Global identification of the substrates of protein crosslinking enzyme and the development of preventive drug in tissue fibrosisPrincipal Investigator

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Analysis of mechanism and development of regulation approach in liver fibrosis via transglutaminasePrincipal Investigator

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Development of novel cancer drug based on pathway analysis for specific cell death of hepatocellular carcinoma treated with acyclic retinoidPrincipal Investigator

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[Book] もっとよくわかる！線維化と疾患2023

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[Book] 食品・バイオにおける最新の酵素利用 井上國世 監修2019

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[Book] 組織の線維化に伴い架橋される基質タンパク質群の網羅的同定・解析2017

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[Book] Transglutaminase：Multiple Functional Modifiers and Targets for New Drug Discovery - Preferred Substrate Structure of Transglutaminases.2016

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[Journal Article] Inhibition of Transglutaminase 2 Reduces Peritoneal Injury in a Chlorhexidine-Induced Peritoneal Fibrosis Model2023

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[Journal Article] Development of peptide-based biosensors for detecting cross-linking and deamidation activities of transglutaminases2023

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[Journal Article] Tissue transglutaminase exacerbates renal fibrosis via alternative activation of monocyte-derived macrophages2023

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[Journal Article] Novel function of transglutaminase 2 in extracellular histone-induced acute lung injury2023

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[Journal Article] Role of Transglutaminase 2 in Cell Death, Survival, and Fibrosis.2021

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TATSUKAWA HIDEKI 辰川英樹

Tatsukawa Hideki 辰川英樹

TATSUKAWA Hideki 辰川英樹

[Book] 食品・バイオにおける最新の酵素利用　井上國世　監修2019