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Kinoshita Chisato  木下 千智

ORCIDConnect your ORCID iD *help
Researcher Number 10567085
Other IDs
Affiliation (Current) 2025: 帝京大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2023 – 2024: 帝京大学, 医学部, 講師
2020 – 2023: 帝京大学, 医学部, 助教
2015 – 2018: 帝京大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 48040:Medical biochemistry-related / Neurochemistry/Neuropharmacology / General pharmacology
Except Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Basic Section 48030:Pharmacology-related
Keywords
Principal Investigator
酸化ストレス / 神経変性疾患 / microRNA / グルタチオン / RNA結合タンパク質 / GTRAP3-18 / マイクロバブル超音波法 / 神経保護 / 脳内送達 / マイクロバブル … More / 内因性抗酸化物質 / 経鼻投与 / ドラッグデリバリー / 核酸薬 / 神経保護効果 / 蛋白質 / 脳神経疾患 / タンパク質 / 発現制御 / miR96 / miR-96 … More
Except Principal Investigator
グルタチオン / 骨髄幹細胞 / 尿酸 / プリン体 / システイントランスポーター / トランスポーター Less
  • Research Projects

    (6 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (4 People)
  •  組織幹細胞機能におけるプリン体代謝物の役割

    • Principal Investigator
      松村 暢子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Teikyo University
  •  Analysis of novel peptide nucleic acids against neurodegeneration

    • Principal Investigator
      青山 晃治
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Teikyo University
  •  Development of Nucleic Acid Therapeutics Using Microbubbles Combined with Ultrasound for Neurodegenerative Diseases.Principal Investigator

    • Principal Investigator
      Kinoshita Chisato
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Teikyo University
  •  The effect of purine derivatives on the activity of bone marrow stem cells

    • Principal Investigator
      Matsumura Nobuko
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Teikyo University
  •  Epigenetic regulation of novel neuroprotective proteinsPrincipal Investigator

    • Principal Investigator
      Kinoshita Chisato
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Teikyo University
  •  Unraveling the neuroprotective mechanism of rhythmic microRNAPrincipal Investigator

    • Principal Investigator
      Kinoshita Chisato
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Teikyo University

All 2023 2022 2018 2017 2016

All Presentation Patent

  • [Patent] MIR-96-5P INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME2023

    • Inventor(s)
      Chisato Kinoshita
    • Industrial Property Rights Holder
      Chisato Kinoshita
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Acquisition Date
      2023
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21K06846
  • [Presentation] Inhibition of miR-96-5p in the mouse brain increases glutathione levels by indirectly modifying GTRAP3-18 expression.2023

    • Author(s)
      Chisato Kinoshita, Koji Aoyama, Ryo Suzuki, Nobuko Matsumura, Daiki Omata, Kazuo Maruyama, Toshio Nakaki
    • Organizer
      The 97th Annual Meeting of the Japanese Pharmacological Society
    • Data Source
      KAKENHI-PROJECT-21K06846
  • [Presentation] Targeted Delivery of MicroRNA-96-5p Inhibitor in the Mouse Brain Using Microbubbles and Ultrasound Technology Enhances Neuroprotection via Increasing Glutathione Levels2023

    • Author(s)
      Chisato Kinoshita, Kazue Kikuchi-Utsumi, Koji Aoyama, Ryo Suzuki, Yayoi Okamoto, Nobuko Matsumura, Daiki Omata, Kazuo Maruyama, Toshio Nakaki
    • Organizer
      RNA Therapeutics: From Concept to Clinic
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06846
  • [Presentation] TheNeuroprotective Effect of a miR-96-5p Inhibitor: Delivery to Brain via the Blood Brain Barrier2023

    • Author(s)
      Chisato Kinoshita, Koji Aoyama, Toshio Nakaki
    • Organizer
      8th Neurological Disorder Summit
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06846
  • [Presentation] マイクロバブル超音波技術を用いたmiR-96-5p阻害薬の脳内送達による神経保護効果およびミクログリア活性への影響2022

    • Author(s)
      木下 千智
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06846
  • [Presentation] The neuroprotective effect of a miR-96-5p inhibitor delivery to brain using microbubbles and ultrasound technology.2022

    • Author(s)
      Chisato Kinoshita
    • Organizer
      14th International Conference on Dementia, Alzheimer and Related Diseases
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06846
  • [Presentation] マイクロバブル超音波技術を用いたmiR-96-5p機能抑制薬の脳内送達による神経保護作用とオートファジー活性化2022

    • Author(s)
      木下 千智
    • Organizer
      第96回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06846
  • [Presentation] miR-96-5p modulates RNA-binding proteins that down-regulate GTRAP3-182018

    • Author(s)
      Kinoshita C, Nakaki T, Aoyama K.
    • Organizer
      The 92th Annual Meeting of the Japanese Pharmacological Society
    • Data Source
      KAKENHI-PROJECT-17K18122
  • [Presentation] Dual Control of Glutathione Regulation in Neuroprotection2018

    • Author(s)
      Chisato Kinoshita
    • Organizer
      2nd Innovations and State of the Art In Dementia Research
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18122
  • [Presentation] GTRAP3-18 regulated by RNA-binding proteins under the control of microRNA2018

    • Author(s)
      Chisato Kinoshita
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18122
  • [Presentation] Dual Control of Glutathione Regulation in Neuroprotection2018

    • Author(s)
      Kinoshita C, Aoyama K, Nakaki T.
    • Organizer
      2nd Innovations and State of the Art In Alzheimer’s & Dementia Research
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18122
  • [Presentation] GTRAP3-18 regulated by RNA-binding proteins under the control of microRNA2018

    • Author(s)
      Kinoshita C, Nakaki T.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18122
  • [Presentation] microRNA制御を受けるRNA結合タンパク質群によるGTRAP3-18の調節2017

    • Author(s)
      木下 千智
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎県)
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15K18995
  • [Presentation] Regulation of GTRAP3-18 by RNA-binding proteins modulated by microRNA2017

    • Author(s)
      Chisato Kinoshita
    • Organizer
      第90回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K18122
  • [Presentation] miR-96-5pに制御されるGTRAP3-18負調節因子の同定2016

    • Author(s)
      木下千智、内海計、押鐘浩之、渡部正彦、中木敏夫
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15K18995
  • 1.  Matsumura Nobuko (30317698)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 2.  青山 晃治 (00420943)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 3.  鈴木 亮 (90384784)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  杉山 亨 (40242036)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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