SEKIGUCHI Yukari 関口縁

Researcher Number	10568653
Affiliation (based on the past Project Information) *help	2016 – 2019: 千葉大学, 大学院医学研究院, 助教 2014 – 2015: 千葉大学, 医学(系)研究科(研究院), 助教 2012 – 2013: 千葉大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Neurology
Keywords	Principal Investigator 化学療法誘発性末梢神経障害 / 感覚神経 / 軸索興奮性 / パクリタキセル / 神経障害性疼痛 / 化学療法誘発性ニューロパチー / 薬剤性ニューロパチー / 神経軸索機能検査 / プロテアソーム阻害剤 / 化学療法性末梢神経障害 … More / プロテオソーム阻害薬 / 化学療法誘発性ポリニューロパチー / 軸索イオンチャネル機能評価 / 下肢感覚神経 / プロテアソーム阻害薬 / 軸索イオンチャネル / 末梢神経障害 / 糖尿病神経障害 / 軸索興奮機能検査 / 軸索機能検査 / 糖尿病性神経障害 Less

パクリタキセル誘発性末梢神経障害の病態解明と早期治療法の開発Principal Investigator
- Principal Investigator
  
  関口縁
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Chiba University
The pathophysiology and treatment of proteasome inhibitor induced polyneuropathyPrincipal Investigator
- Principal Investigator
  
  Sekiguchi Yukari
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Chiba University
Establishment of a therapeutic strategy based on axonal ion chanel in diabetic polyneuropathy.Principal Investigator
- Principal Investigator
  
  SEKIGUCHI Yukari
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Chiba University

All 2019 2018 2017 2016 2013

All Journal Article Presentation

[Journal Article] Membrane property changes in most distal motor axons in chronic inflammatory demyelinating polyneuropathy.2019
- Author(s)
  Amino H, Shibuya K, Misawa S, Sekiguchi Y, Beppu M, Suichi T, Suzuki YI, Tsuneyama A, Kuwabara S.
- Journal Title
  
  Muscle Nerve
  
  Volume: E pub ahead online
- Data Source
  KAKENHI-PROJECT-17K09792
[Journal Article] Diagnostic Challenges Posed by Preceding Peripheral Neuropathy in Very Late-onset Spinocerebellar Ataxia Type 32019
- Author(s)
  Sugiyama A, Sekiguchi Y, Beppu M, Ishige T, Matsushita K, Kuwabara S.
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 1 Pages: 119-122
- DOI
  10.2169/internalmedicine.1382-18
- NAID
  130007542250
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09004, KAKENHI-PROJECT-17K15768, KAKENHI-PROJECT-19KT0019, KAKENHI-PROJECT-17K09792
[Journal Article] A study supporting possible expression of inward-rectifying potassium channel 2.1 channels in peripheral nerve in a patient with Andersen-Tawil syndrome.2019
- Author(s)
  Shibuya K, Tsuneyama A, Beppu M, Misawa S, Sekiguchi Y, Amino H, Suzuki YI, Suichi T, Nakamura K, Kuwabara S
- Journal Title
  
  Muscle and Nerve
  
  Volume: 59 Issue: 4 Pages: 133-137
- DOI
  10.1002/mus.26430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16110, KAKENHI-PROJECT-17K09774, KAKENHI-PROJECT-17K09792
[Journal Article] A model to predict the probability of acute inflammatory demyelinating polyneuropathy.2019
- Author(s)
  Tan CY, Sekiguchi Y, Goh KJ, Kuwabara S, Shahrizaila N.
- Journal Title
  
  Clin Neurophysiol
  
  Volume: 131 Issue: 1 Pages: 63-69
- DOI
  10.1016/j.clinph.2019.09.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09792
[Journal Article] Proposal of new clinical diagnostic criteria for POEMS syndrome2018
- Author(s)
  Suichi Tomoki、Misawa Sonoko、Sato Yasunori、Beppu Minako、Sakaida Emiko、Sekiguchi Yukari、Shibuya Kazumoto、Watanabe Keisuke、Amino Hiroshi、Kuwabara Satoshi
- Journal Title
  
  Journal of Neurology, Neurosurgery & Psychiatry
  
  Volume: 90 Issue: 2 Pages: 133-137
- DOI
  10.1136/jnnp-2018-318514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16110, KAKENHI-PROJECT-16K09692, KAKENHI-PROJECT-17K09774, KAKENHI-PROJECT-19K07955, KAKENHI-PROJECT-17K09792
[Journal Article] Prodromal muscle cramps predict rapid motor functional decline in amyotrophic lateral sclerosis2018
- Author(s)
  Shibuya Kazumoto、Misawa Sonoko、Sekiguchi Yukari、Beppu Minako、Amino Hiroshi、Suichi Tomoki、Suzuki Yo-ichi、Tsuneyama Atsuko、Kuwabara Satoshi
- Journal Title
  
  Journal of Neurology, Neurosurgery & Psychiatry
  
  Volume: 90 Issue: 2 Pages: 242-243
- DOI
  10.1136/jnnp-2018-318446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16110, KAKENHI-PROJECT-17K09792
[Journal Article] Safety and efficacy of eculizumab in Guillain-Barre syndrome: a multicentre, double-blind, randomised phase 2 trial2018
- Author(s)
  Misawa S, Kuwabara S, Sato Y, Yamaguchi N, Nagashima K, Katayama K, Sekiguchi Y, et al
- Journal Title
  
  Lancet neuro
  
  Volume: 17 Issue: 6 Pages: 519-529
- DOI
  10.1016/s1474-4422(18)30114-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09792, KAKENHI-PROJECT-18H02745
[Journal Article] Altered cerebral blood flow in the anterior cingulate cortex is associated with neuropathic pain.2018
- Author(s)
  Watanabe K, Hirano S, Kojima K, Nagashima K, Mukai H, Sato T, Takemoto M, Matsumoto K, Iimori T, Isose S, Omori S, Shibuya K, Sekiguchi Y, Beppu M, Amino H, Suichi T, Yokote K, Uno T, Kuwabara S, Misawa S.
- Journal Title
  
  Journal of Neurology Neurosurgry Psychiatry
  
  Volume: 印刷中 Issue: 10 Pages: 1082-1087
- DOI
  10.1136/jnnp-2017-316601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16110, KAKENHI-PROJECT-17K09791, KAKENHI-PROJECT-17K09792, KAKENHI-PROJECT-16K09229
[Journal Article] Pain-related evoked potentials after intraepidermal electrical2017
- Author(s)
  Omori S, Isose S, Misawa S, Watanabe K, Sekiguchi Y, Shibuya K, Beppu M, Amino
- Journal Title
  
  Neuroscience Research
  
  Volume: 印刷中 Pages: 43-48
- DOI
  10.1016/j.neures.2017.03.007
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461305, KAKENHI-PROJECT-26860659, KAKENHI-PROJECT-16K09692, KAKENHI-PROJECT-17K09791, KAKENHI-PROJECT-17K16110
[Journal Article] Electrophysiology in Fisher syndrome.2017
- Author(s)
  Kuwabara S, Sekiguchi Y, Misawa S
- Journal Title
  
  . Clin Neurophysiol
  
  Volume: 128 Pages: 215-219
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860659
[Journal Article] Safety and efficacy of thalidomide in patients with POEMS syndrome: a multicentre, randomised, double-blind, placebo-controlled trial.2016
- Author(s)
  Misawa S, Sato Y, Katayama K, Nagashima K, Aoyagi R, Sekiguchi Y, Sobue G, Koike H, Yabe I, Sasaki H, Watanabe O, Takashima H, Nishizawa M, Kawachi I, Kusunoki S, Mitsui Y, Kikuchi S, Nakashima I, et al; Japanese POEMS Syndrome for Thalidomide (J-POST) Trial Study Group.
- Journal Title
  
  Lancet Neurol
  
  Volume: 15 Issue: 11 Pages: 1129-37
- DOI
  10.1016/s1474-4422(16)30157-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860659, KAKENHI-PROJECT-16K09692, KAKENHI-PROJECT-16K09697
[Journal Article] A Prospective, Multicenter, Randomized Phase II Study to Evaluate the Efficacy and Safety of Eculizumab in Patients with Guillain-Barré Syndrome (GBS): Protocol of Japanese Eculizumab Trial for GBS (JET-GBS).2016
- Author(s)
  Yamaguchi N, Misawa S, Sato Y, Nagashima K, Katayama K, Sekiguchi Y, et al.
- Journal Title
  
  JMIR Res Protoc
  
  Volume: 5
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860659
[Journal Article] How often and when Fisher syndrome is overlapped by Guillain-Barré syndrome or Bickerstaff brainstem encephalitis?2016
- Author(s)
  Sekiguchi Y, Mori M, Misawa S, Sawai S, Yuki N, Beppu M, Kuwabara S.
- Journal Title
  
  Eur J Neurol
  
  Volume: 23 Pages: 1058-63
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860659
[Presentation] ギラン・バレー症候群の神経伝導検査：各基準の特徴2019
- Author(s)
  関口　縁、三澤　園子、中村　圭吾、常山　篤子、鈴木　陽一、水地　智基、網野　寛、別府　美奈子、澁谷　和幹、桑原　聡
- Organizer
  第30回日本末梢神経学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09792
[Presentation] ギラン・バレー症候群の神経伝導検査：各基準の特徴2019
- Author(s)
  関口縁,三澤園子,中村圭吾,常山篤子,鈴木陽一,水地智基,網野寛,別府美奈子，澁谷和幹，桑原聡
- Organizer
  第60回日本神経学会
- Data Source
  KAKENHI-PROJECT-17K09792
[Presentation] ギラン・バレー症候群に対するエクリズマブ治療―対象患者像2019
- Author(s)
  関口　縁
- Organizer
  第60回日本神経学会
- Data Source
  KAKENHI-PROJECT-17K09792
[Presentation] エクリズマブ治療によるGuillan-Barré症候群（GBS）の長期予後： JET-GBS study追跡調査2019
- Author(s)
  関口　縁、三澤　園子、水地　智基、國分　則人、海田　賢一、鈴木　重明、桑原　基、楠　進、桑原　聡
- Organizer
  第31回日本神経免疫学会
- Data Source
  KAKENHI-PROJECT-17K09792
[Presentation] ギラン・バレー症候群における顔面神経麻痺2018
- Author(s)
  関口　縁、三澤　園子、澁谷　和幹、桑原　聡
- Organizer
  神経免疫学会
- Data Source
  KAKENHI-PROJECT-17K09792
[Presentation] ギラン・バレー症候群の予後予測に神経伝導検査は有用か？2018
- Author(s)
  関口縁，三澤園子，常山篤子，鈴木陽一，水地智基，網野寛，別府美奈子，澁谷和幹，桑原聡
- Organizer
  日本神経学会
- Data Source
  KAKENHI-PROJECT-17K09792
[Presentation] ：ギラン・バレー症候群におけるエクリズマブの有効性のメカニズム：神経伝導検査所見から2018
- Author(s)
  関口縁，三澤園子，常山篤子，鈴木陽一，水地智基，網野寛、別府美奈子、桑原基、楠進、桑原聡
- Organizer
  臨床神経生理学会
- Data Source
  KAKENHI-PROJECT-17K09792
[Presentation] 脱髄性ニューロパチーの電気生理診断の進歩；Fisher症候群2018
- Author(s)
  関口　縁
- Organizer
  臨床神経生理学会
- Data Source
  KAKENHI-PROJECT-17K09792
[Presentation] 高齢Guillan-Barré症候群患者の予後2016
- Author(s)
  関口　縁、三澤　園子、渡辺　慶介、網野　寛、磯瀬　沙希里、桑原　聡
- Organizer
  第27回末梢神経学会学術集会
- Place of Presentation
  大阪国際会議場、大阪府
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-26860659
[Presentation] How often is Fisher syndrome overlapped with Guillan-Barre syndrome or Bickerstuff brainstem encephalitis.2016
- Author(s)
  Yukari Sekiguchi, Sonoko Misawa, Amino Hiroshi, Yuta Iwai, Minako Beppu,Nobuhiro Yuki, Satoshi Kuwabara
- Organizer
  Inflammatory Neuropathy Consortium of the peripheral nerve society
- Place of Presentation
  Glasgow, UK
- Year and Date
  2016-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860659
[Presentation] CIDP の軸索特性: 臨床病型に基づく検討2016
- Author(s)
  渡辺　慶介、三澤　園子、渋谷　和幹、関口　　縁、別府美奈子、網野　　寛、
- Organizer
  第46回臨床神経生理学会学術集会
- Place of Presentation
  ホテルハマツ、福島県郡山市
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-26860659
[Presentation] Fisher 症候群の電気生理2016
- Author(s)
  関口　　縁
- Organizer
  第46回臨床神経生理学会学術集会
- Place of Presentation
  ホテルハマツ、福島県郡山市
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-26860659
[Presentation] Difference in small fiber involvement in CIDP and POEMS syndrome.2016
- Author(s)
  Sagiri Isose, Sonoko Misawa, Shigeki Oomori, Yukari Sekiguchi, Minako Beppu, Keisuke Watanabe, Satoshi Kuwabara
- Organizer
  Inflammatory Neuropathy Consortium of the peripheral nerve society
- Place of Presentation
  Glasgow, UK
- Year and Date
  2016-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860659
[Presentation] 本邦のGuillan-Barré症候群における人工呼吸器装着リスク2016
- Author(s)
  関口　縁、三澤　園子、澁谷　和幹、渡辺　慶介、網野　寛、水地　智基、桑原　聡
- Organizer
  第28回日本神経免疫学会学術集会
- Place of Presentation
  長崎ブリックホール、長崎県長崎市
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-26860659
[Presentation] ギラン・バレー症候群の予後予測における神経伝導検査の有用性2016
- Author(s)
  関口　　縁、三澤　園子、別府美奈子、澁谷　和幹、渡辺　慶介、網野　　寛、桑原　聡
- Organizer
  第46回臨床神経生理学会学術集会
- Place of Presentation
  ホテルハマツ、福島県郡山市
- Year and Date
  2016-10-27
- Invited
- Data Source
  KAKENHI-PROJECT-26860659
[Presentation] Typical およびAtypical CIDPにおける呼吸不全例の検討2016
- Author(s)
  織田史子、渡辺慶介、三澤園子、関口縁、桑原聡
- Organizer
  第27回末梢神経学会学術集会
- Place of Presentation
  大阪国際会議場、大阪府
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-26860659
[Presentation] 下肢感覚神経の軸索イオンチャネル機能評価：神経近傍針電極の有用性2013
- Author(s)
  関口　縁
- Organizer
  臨床神経生理学会
- Place of Presentation
  高知県立県民文化ホール
- Data Source
  KAKENHI-PROJECT-24790874

1. 澁谷和幹

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. 三澤園子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SEKIGUCHI Yukari 関口 縁

Research Projects

Research Products

Co-Researchers

パクリタキセル誘発性末梢神経障害の病態解明と早期治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The pathophysiology and treatment of proteasome inhibitor induced polyneuropathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of a therapeutic strategy based on axonal ion chanel in diabetic polyneuropathy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Membrane property changes in most distal motor axons in chronic inflammatory demyelinating polyneuropathy.2019

Author(s)

Journal Title

Data Source

[Journal Article] Diagnostic Challenges Posed by Preceding Peripheral Neuropathy in Very Late-onset Spinocerebellar Ataxia Type 32019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] A study supporting possible expression of inward-rectifying potassium channel 2.1 channels in peripheral nerve in a patient with Andersen-Tawil syndrome.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A model to predict the probability of acute inflammatory demyelinating polyneuropathy.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proposal of new clinical diagnostic criteria for POEMS syndrome2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prodromal muscle cramps predict rapid motor functional decline in amyotrophic lateral sclerosis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Safety and efficacy of eculizumab in Guillain-Barre syndrome: a multicentre, double-blind, randomised phase 2 trial2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Altered cerebral blood flow in the anterior cingulate cortex is associated with neuropathic pain.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pain-related evoked potentials after intraepidermal electrical2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Electrophysiology in Fisher syndrome.2017

Author(s)

Journal Title

Data Source

[Journal Article] Safety and efficacy of thalidomide in patients with POEMS syndrome: a multicentre, randomised, double-blind, placebo-controlled trial.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Prospective, Multicenter, Randomized Phase II Study to Evaluate the Efficacy and Safety of Eculizumab in Patients with Guillain-Barr&eacute; Syndrome (GBS): Protocol of Japanese Eculizumab Trial for GBS (JET-GBS).2016

SEKIGUCHI Yukari 関口縁

[Journal Article] A Prospective, Multicenter, Randomized Phase II Study to Evaluate the Efficacy and Safety of Eculizumab in Patients with Guillain-Barré Syndrome (GBS): Protocol of Japanese Eculizumab Trial for GBS (JET-GBS).2016

[Journal Article] How often and when Fisher syndrome is overlapped by Guillain-Barré syndrome or Bickerstaff brainstem encephalitis?2016

[Presentation] エクリズマブ治療によるGuillan-Barré症候群（GBS）の長期予後： JET-GBS study追跡調査2019

[Presentation] ：ギラン・バレー症候群におけるエクリズマブの有効性のメカニズム：神経伝導検査所見から2018

[Presentation] 高齢Guillan-Barré症候群患者の予後2016

[Presentation] 本邦のGuillan-Barré症候群における人工呼吸器装着リスク2016