Kayamori Kou 栢森高

Researcher Number	10569841
Other IDs
Affiliation (based on the past Project Information) *help	2022 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 講師 2020 – 2021: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2015 – 2017: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2013 – 2016: 東京医科歯科大学, 医歯(薬)学総合研究科, 助教
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Basic Section 57020:Oral pathobiological science-related Except Principal Investigator Pathobiological dentistry/Dental radiology / Basic Section 57060:Surgical dentistry-related / Basic Section 57020:Oral pathobiological science-related
Keywords	Principal Investigator 口腔扁平上皮癌 / 癌関連線維芽細胞 / NOTCHシグナル / プロテオーム解析 / WNTリガンド / 口腔癌 / 腫瘍関連マクロファージ / リンパ節転移 / 癌微小環境 / 血管新生 … More / Oral cancer / Notch3 / Oral Cancer / Angiogenesis / CAF / NOTCH3 … More Except Principal Investigator 破骨細胞 / 骨吸収 / Notch / RANKL / 骨破壊 / 遠隔転移 / 中心性骨内癌 / 顎骨中心性癌 / 口腔がん / 原発性骨内癌 / 骨転移 / 破骨細胞誘導 / 骨浸潤 / IL-1 / 破骨細胞前駆細胞 / 口腔扁平上皮癌 / 扁平上皮癌 / 癌幹細胞 / CAF / Notch3 / notch / 骨髄幹細胞 / 癌 / 癌細胞 / VEGF / 血管新生 / リンパ管 / 血管 / 腫瘍 / 癌転移 / 脈管新生 / 間質細胞 / IL-6 / 口腔癌 Less

原発性骨内癌の病態解明による新規診断技術・革新的治療法開発の基盤構築研究
- Principal Investigator
  
  黒嶋雄志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Medical and Dental University
癌関連線維芽細胞が活性化するシグナルに着目した新たな口腔癌分子治療法の構築Principal Investigator
- Principal Investigator
  
  栢森高
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of the novel osteoclastogenesis system induced by oral squamous cell carcinoma cells
- Principal Investigator
  
  Ikeda Tohru
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Tokyo Medical and Dental University
The role for cancer-associated fibroblasts in lymph node metastasisPrincipal Investigator
- Principal Investigator
  
  KAYAMORI Kou
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokyo Medical and Dental University
The role of Cancer-Associated Fibroblasts in Anigogenesis regulated by NOTCH signalingPrincipal Investigator
- Principal Investigator
  
  Kayamori Kou
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokyo Medical and Dental University
Comprehensive analyses of the mechanism of bone destruction by oral cancer
- Principal Investigator
  
  Yamaguchi Akira
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Dental College
  Tokyo Medical and Dental University
Analysis of the metastatic activity of headn and neck cancer from the asepect of lymphangiogenesis
- Principal Investigator
  
  Katsube Ken-ichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tohto College of Health Sciences

All 2022 2018 2017 2016 2015 2013

All Journal Article Presentation

[Journal Article] IL-1 Generated by Oral Squamous Cell Carcinoma Stimulates Tumor-Induced and RANKL-Induced Osteoclastogenesis: A Possible Mechanism of Bone Resorption Induced by the Infiltration of Oral Squamous Cell Carcinoma2022
- Author(s)
  Fukawa Yuki、Kayamori Kou、Tsuchiya Maiko、Ikeda Tohru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 1 Pages: 688-688
- DOI
  10.3390/ijms24010688
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16941, KAKENHI-PROJECT-20H03857
[Journal Article] Leukemia inhibitory factor produced by fibroblasts within tumor stroma participates in invasion of oral squamous cell carcinoma.2018
- Author(s)
  Ohata Y, Tsuchiya M, Hirai H, Yamaguchi S, Akashi T, Sakamoto K, Yamaguchi A, Ikeda T, Kayamori K
- Journal Title
  
  PLos One
  
  Volume: 13 Issue: 2 Pages: e0191865-e0191865
- DOI
  10.1371/journal.pone.0191865
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15791, KAKENHI-PROJECT-16K20410
[Journal Article] CD163-Positive Macrophages Within Tumor Stroma Are Associated With Lymphangiogenesis and Ltmph Node Metastasis in Oral Squamous Cell Carcinoma2017
- Author(s)
  Yamagata Y, Tomioka H, Sakamoto K, Sato K, Harada H, Ikeda T, Kayamori K
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery
  
  Volume: 印刷中 Issue: 10 Pages: 2144-2153
- DOI
  10.1016/j.joms.2017.03.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K20410
[Journal Article] Xenograft model of the mandibular bone destruction of human oral cancers.2016
- Author(s)
  Tohyama R, Kayamori K, Sato K, Hamagaki M, Sakamoto K, Yasuda H, Yamaguchi A
- Journal Title
  
  J Oral Patholog Med
  
  Volume: 45 Issue: 5 Pages: 356-364
- DOI
  10.1111/jop.12376
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25253098
[Journal Article] KRT17 is induced in oral cancer and facilitate tumor gowth.2016
- Author(s)
  Khanom R, Nguyen CTK, Kayamori K, Zhao X, Morita K, Yamaguchi A, Sakamoto K
- Journal Title
  
  PlosOne
  
  Volume: 11 Issue: 8 Pages: e0161163-e0161163
- DOI
  10.1371/journal.pone.0161163
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253098, KAKENHI-PROJECT-25462915, KAKENHI-PROJECT-16K15791
[Journal Article] A facile one-step strategy for the generation of conditional knockout mice to explore the role of Notch1 in oroesophageal tumorigenesis.2016
- Author(s)
  Mandasari M, Sawangarun W, Katsube K, Kayamori K, Yamaguchi A, Sakamoto K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 469 Pages: 761-767
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462915
[Journal Article] A facile one-step strategy for the generation of conditional knockout mice to explore the role of Notch1 in oroesophageal tumorigenesis.2016
- Author(s)
  Mandasari M, Sawangarun W, Katsube K, Kayamori K, Yamaguchi A, Sakamoto K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 469(3) Issue: 3 Pages: 761-767
- DOI
  10.1016/j.bbrc.2015.12.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462848, KAKENHI-PROJECT-25462915
[Journal Article] A ficile one-step strategy for the egeneration of conditional knockout mice to explore the role of Notch1 in oroesophageal tumorigenesis.2016
- Author(s)
  Mandasari M, Sawangarun W, Ktsube K, Kayamori K, Yamaguchi A, Sakamoto K
- Journal Title
  
  Biochem Bioph Res Co
  
  Volume: 469 Pages: 761-767
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25253098
[Journal Article] THBS1 is induced by TGFB1 in the cancer stroma and promotes invasion of oral squamous cell carcinoma.2016
- Author(s)
  Pal SK, Nguyen CTK, Morita, K, Miki Y, Kayamori K, Yamaguchi A, Sakamoto K
- Journal Title
  
  J Oral Pathol Med
  
  Volume: 45 Issue: 10 Pages: 730-739
- DOI
  10.1111/jop.12430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25253098, KAKENHI-PROJECT-16K15791
[Journal Article] NOTCH3 Is Induced in Cancer-Associated Fibroblasts and Promotes Angiogenesis in Oral Squamous Cell Carcinoma2016
- Author(s)
  Kayamori K, Katsube K, Sakamoto K, Ohyama Y, Hirai H, Yukimori A, Ohata Y, Akashi T, Saitoh M, Harada K, Harada H, Yamaguchi A
- Journal Title
  
  PLoS ONE
  
  Volume: 11 Issue: 4 Pages: 223-231
- DOI
  10.1371/journal.pone.0154112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861543, KAKENHI-PROJECT-25253098, KAKENHI-PROJECT-25462915, KAKENHI-PROJECT-16K15791
[Journal Article] Transforming growth factor-βsynthesized by stromal cells and cancer cells participates in bone resorption induced by oral squamous cell carcinoma2015
- Author(s)
  Ryosuke Nakamura,Kou Kayamori,Erika Oue,Kei Sakamoto,Kiyoshi Harada,Akira Yamaguchi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 458 Issue: 4 Pages: 777-782
- DOI
  10.1016/j.bbrc.2015.02.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25861916, KAKENHI-PROJECT-26670657, KAKENHI-PROJECT-25253098
[Journal Article] RANKL synthesized by both stromal cells and cancer cells plays a crucial role in osteoclastic bone resorption induced by oral cancer2013
- Author(s)
  Kiyoshi Sato, Ji-Won Lee, Kei Sakamoto, Tadahiro Iimura, Kou Kayamori, Hisataka Yasuda, Masanobu Shindoh, Masako Ito, Ken Omura, Akira Yamaguchi
- Journal Title
  
  American Journal of Pathology
  
  Volume: 182 Issue: 5 Pages: 1890-1899
- DOI
  10.1016/j.ajpath.2013.01.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01113, KAKENHI-PROJECT-22249061, KAKENHI-PROJECT-23390417, KAKENHI-PROJECT-24659807, KAKENHI-PROJECT-25253098
[Presentation] IL-1を介した口腔扁平上皮癌による破骨細胞誘導の促進2022
- Author(s)
  布川　裕規、栢森　高、池田　通
- Organizer
  第33回日本臨床口腔病理学会
- Data Source
  KAKENHI-PROJECT-20H03857
[Presentation] 口腔扁平上皮癌における癌関連線維芽細胞の生物学的重要性2017
- Author(s)
  大畑八重、栢森高、平井秀明、土谷麻衣子、山口聰、原田浩之、坂本啓、池田通
- Organizer
  第２８回日本臨床口腔病理学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-16K20410

1. 坂本啓 (00302886)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. Yamaguchi Akira (00142430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. Katsube Ken-ichi (20233760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Ikeda Tohru (00211029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 飯村忠浩 (20282775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 樋田泰浩 (30399919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 間石奈湖 (00632423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 進藤正信 (20162802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 黒嶋雄志 (00610669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 東野史裕 (50301891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 菅澤威仁 (60821840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. LEE J.-W.

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 土谷麻衣子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kayamori Kou 栢森 高

Research Projects

Research Products

Co-Researchers

原発性骨内癌の病態解明による新規診断技術・革新的治療法開発の基盤構築研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

癌関連線維芽細胞が活性化するシグナルに着目した新たな口腔癌分子治療法の構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the novel osteoclastogenesis system induced by oral squamous cell carcinoma cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role for cancer-associated fibroblasts in lymph node metastasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of Cancer-Associated Fibroblasts in Anigogenesis regulated by NOTCH signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analyses of the mechanism of bone destruction by oral cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the metastatic activity of headn and neck cancer from the asepect of lymphangiogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] IL-1 Generated by Oral Squamous Cell Carcinoma Stimulates Tumor-Induced and RANKL-Induced Osteoclastogenesis: A Possible Mechanism of Bone Resorption Induced by the Infiltration of Oral Squamous Cell Carcinoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Leukemia inhibitory factor produced by fibroblasts within tumor stroma participates in invasion of oral squamous cell carcinoma.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD163-Positive Macrophages Within Tumor Stroma Are Associated With Lymphangiogenesis and Ltmph Node Metastasis in Oral Squamous Cell Carcinoma2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Xenograft model of the mandibular bone destruction of human oral cancers.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KRT17 is induced in oral cancer and facilitate tumor gowth.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A facile one-step strategy for the generation of conditional knockout mice to explore the role of Notch1 in oroesophageal tumorigenesis.2016

Author(s)

Journal Title

Data Source

[Journal Article] A facile one-step strategy for the generation of conditional knockout mice to explore the role of Notch1 in oroesophageal tumorigenesis.2016

Author(s)

Journal Title

DOI

Data Source

Kayamori Kou 栢森高