ITO KEISUKE 伊藤圭祐

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Ito Keisuke 伊藤圭祐

ITO Keisuke 伊藤圭祐

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Researcher Number	10575468
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2019 – 2023: 神戸大学, 医学研究科, 助教 2016: 神戸大学, 医学研究科, 助教 2015: 神戸大学, 医学(系)研究科(研究院), 助教 2014: 神戸大学, 大学院医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Basic Section 48010:Anatomy-related / Experimental pathology Except Principal Investigator Biological Sciences
Keywords	Principal Investigator Phox2b / 交感神経系 / 神経芽腫 / シュワン前駆細胞 / RNAシーケンス / シングルセルRNAシーケンス / bipotential progenitor / Phox2b 3'UTR / Notch / 交感神経節 … More / single cell RNA sequence / Phox2B / 自律神経系 / 末梢神経系 / β1-integrin / CRISPR/Cas9 / 細胞内輸送 / 腸管神経系 / 変異型RET / Integrin / 細胞外基質 / Dynein / Rab11 / GDNF / RET … More Except Principal Investigator Dusp6 / Brainbow / 細胞遊走 / 腸管神経堤細胞 / 血管系 / RET / ケモカイン / CXCR4 / タイムラプスイメージング / ライブセルイメージング / 神経栄養因子 / 神経堤細 / イメージング / ヒルシュスプルング病 / 腸管神経系 / 神経前駆細胞 / 神経堤細胞 / 血管発生 / 細胞移動 / 神経発生 Less

前肢に存在する「神経様細胞」の異常産生と、神経芽腫発症の共通分子基盤を探るPrincipal Investigator
- Principal Investigator
  
  伊藤圭祐
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kobe University
Analysis of multipotency and its underlying molecular mechanisms of sympathetic nerve-associating Schwann cell precursorsPrincipal Investigator
- Principal Investigator
  
  Ito Keisuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Kobe University
In vivo imaging of receptor trafficking of RET in organogenesis and pathogenesisPrincipal Investigator
- Principal Investigator
  
  Ito Keisuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kobe University
Vascular tissues that supports migration of enteric neural progenitors
- Principal Investigator
  
  ENOMOTO HIDEKI
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
  The Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Pcgf1 gene disruption reveals primary involvement of epigenetic mechanism in neuronal subtype specification in the enteric nervous system2023
- Author(s)
  Putra Bayu Pratama、Ito Keisuke、Cirillo Carla、Sunardi Mukhamad、Koseki Haruhiko、Uesaka Toshihiro、Enomoto Hideki
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 65 Issue: 8 Pages: 461-469
- DOI
  10.1111/dgd.12880
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KF0255, KAKENHI-PROJECT-22K07023, KAKENHI-PROJECT-23K23895
[Journal Article] A Single RET Mutation in Hirschsprung Disease Induces Intestinal Aganglionosis Via a Dominant-Negative Mechanism2022
- Author(s)
  Sunardi Mukhamad、Ito Keisuke、Sato Yuya、Uesaka Toshihiro、Iwasaki Mitsuhiro、Enomoto Hideki
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 14 Issue: 6 Pages: 1505-1524
- DOI
  10.1016/j.jcmgh.2022.12.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07023, KAKENHI-PROJECT-20K21526, KAKENHI-PROJECT-23K23895
[Journal Article] Increased RET Activity Coupled with a Reduction in the <i>RET</i> Gene Dosage Causes Intestinal Aganglionosis in Mice2021
- Author(s)
  Okamoto Mitsumasa、Uesaka Toshihiro、Ito Keisuke、Enomoto Hideki
- Journal Title
  
  eneuro
  
  Volume: 8 Issue: 3 Pages: 1-12
- DOI
  10.1523/eneuro.0534-20.2021
- NAID
  120007177532
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07267, KAKENHI-PROJECT-20K21526
[Journal Article] Live visualization of a functional RET‐EGFP chimeric receptor in homozygous knock‐in mice2021
- Author(s)
  Sunardi Mukhamad、Ito Keisuke、Enomoto Hideki
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 63 Issue: 6 Pages: 285-294
- DOI
  10.1111/dgd.12740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07267
[Journal Article] Retrograde transport of neurotrophic factor signaling: implications in neuronal development and pathogenesis.2016
- Author(s)
  Keisuke Ito and Hideki Enomoto
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 160 Issue: 2 Pages: 77-85
- DOI
  10.1093/jb/mvw037
- NAID
  40020914022
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21147
[Journal Article] A promoter-level mammalian expression atlas.2014
- Author(s)
  Forrest, A.R.R., Kawaji, H., Rehli, M., Baillie, J.K, de Hoon, M.J.L., Haberle, V., Lassmann, T., Kulakovskiy, I.V., Lizio, M., Itoh, M., Andersson, R., Mungall, C. J.,et al.
- Journal Title
  
  Nature
  
  Volume: 507 Issue: 7493 Pages: 462-470
- DOI
  10.1038/nature13182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PLANNED-22122005, KAKENHI-PROJECT-22228005, KAKENHI-PROJECT-23689044, KAKENHI-PROJECT-23790791, KAKENHI-PROJECT-24689042, KAKENHI-PUBLICLY-25118732, KAKENHI-PROJECT-25330333, KAKENHI-PROJECT-26713029
[Journal Article] Differential roles of epigenetic changes and Foxp3 expression in regulatory Tcell-specific transcriptional regulation.2014
- Author(s)
  Morikawa H, Ohkura N, Vandenbon A, Itoh M Nagao-Sato S, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest AR, Standley DM, Date H, Sakaguchi S; FANTOM Consortium. Collaborators(259) Enomoto H, etc.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 111 Issue: 14 Pages: 5289-5294
- DOI
  10.1073/pnas.1312717110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22122005, KAKENHI-PROJECT-25330333, KAKENHI-PROJECT-22228005
[Journal Article] GDNF and endothelin 3 regulate migration of enteric neural crest-derived cells via PKA and Rac12013
- Author(s)
  Goto A, Sumiyama K, Kamioka Y, Nakasho E, Ito K, Iwasaki M, Enomoto H, Matsuda M.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 33 Issue: 11 Pages: 4901-4912
- DOI
  10.1523/jneurosci.4828-12.2013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22122005, KAKENHI-PROJECT-22570218, KAKENHI-PROJECT-23370101, KAKENHI-PROJECT-23701053, KAKENHI-PUBLICLY-24113520, KAKENHI-PLANNED-22113002, KAKENHI-PROJECT-221S0001
[Presentation] Cellular Identity of Neurogenic Schwann Cell Precursors2024
- Author(s)
  Hideki Enomoto & Keisuke Ito
- Organizer
  7th International Enteric Nervous System Development Meeting: Connection, Cross-talk and Collaboration
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07023
[Presentation] Sox10 suppresses Schwann cell precursor-derived neurogenesis to prevent ectopic autonomic neurons and tumors2023
- Author(s)
  Keisuke Ito and Hideki Enomoto
- Organizer
  Gordon Research Conference 2023, Neural crest and cranial placodes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07023
[Presentation] Sox10 suppresses Schwann cell precursor-derived neurogenesis to prevent ectopic autonomic neurons and tumors2023
- Author(s)
  Keisuke Ito
- Organizer
  University of Washington and Kobe University joint symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07023
[Presentation] Neurogenic Schwann cell precursors are abundant, show differentiation plasticity and can be tumorigenic in mouse embryos2022
- Author(s)
  Keisuke Ito and Hideki Enomoto
- Organizer
  6th International Symposium on Development of the ENS: the first 1000 days
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07023
[Presentation] FUNCTION OF SCHWANN CELL PRECURSORS AS THE AUTONOMIC NEURAL STEM CELLS2021
- Author(s)
  Hideki Enomoto, Keisuke Ito, Toshihiro Uesaka
- Organizer
  International Society for Stem Cell Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07267
[Presentation] Differentiation plasticity of Schwann cell precursors causes ectopic neurogenesis and tumor pathogenesis2021
- Author(s)
  Keisuke Ito
- Organizer
  CREST多細胞領域第12回Rising Star Webinar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07267
[Presentation] Polarized trafficking of RET tyrosine kinase in migrating enteric-neural crestderived cells2015
- Author(s)
  Keisuke Ito, Hideki Enomoto
- Organizer
  4th International Symposium on "Development of the enteric nervous system:Cells,Singnals,Genes and Therapy"
- Place of Presentation
  オランダ
- Year and Date
  2015-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21147
[Presentation] Polarized intracellular trafficking of RET tyrosine kinase in living neurons2015
- Author(s)
  Keisuke Ito, Hideki Enomoto
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K21147
[Presentation] Chasing the RET Tyrosine Kinase in Living Cells during ENS Development2012
- Author(s)
  K.Ito, H.Enomoto
- Organizer
  3^<rd> International Symposium on Development of the Enteric Nervous System : Cells, Signals and Genes
- Place of Presentation
  The University of Hong Kong (Hong Kong, China)
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PLANNED-22122005
[Presentation] RET51-EGFP mice : A valuable tool for investigating trafficking of the RET tyrosine kinase in living cells and tissues.2011
- Author(s)
  Keisuke Ito
- Organizer
  40^<th> Annual Meeting Neuroscience
- Place of Presentation
  San Diego, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PLANNED-22122005
[Presentation] Polarized trafficking of RET tyrosine kinase in living cells
- Author(s)
  伊藤圭祐・榎本秀樹
- Organizer
  Neurovascular Wiring 2nd International Symposium 2015
- Place of Presentation
  京都
- Year and Date
  2015-01-28 – 2015-01-30
- Invited
- Data Source
  KAKENHI-PLANNED-22122005

1. ENOMOTO HIDEKI (00360511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. UESAKA Toshihiro (90304451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SUNARDI MUKHAMAD

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ITO KEISUKE 伊藤 圭祐

Ito Keisuke 伊藤 圭祐

ITO Keisuke 伊藤 圭祐

Research Projects

Research Products

Co-Researchers

前肢に存在する「神経様細胞」の異常産生と、神経芽腫発症の共通分子基盤を探るPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of multipotency and its underlying molecular mechanisms of sympathetic nerve-associating Schwann cell precursorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vivo imaging of receptor trafficking of RET in organogenesis and pathogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Vascular tissues that supports migration of enteric neural progenitors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Pcgf1 gene disruption reveals primary involvement of epigenetic mechanism in neuronal subtype specification in the enteric nervous system2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Single RET Mutation in Hirschsprung Disease Induces Intestinal Aganglionosis Via a Dominant-Negative Mechanism2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased RET Activity Coupled with a Reduction in the <i>RET</i> Gene Dosage Causes Intestinal Aganglionosis in Mice2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Live visualization of a functional RET‐EGFP chimeric receptor in homozygous knock‐in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Retrograde transport of neurotrophic factor signaling: implications in neuronal development and pathogenesis.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A promoter-level mammalian expression atlas.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential roles of epigenetic changes and Foxp3 expression in regulatory Tcell-specific transcriptional regulation.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GDNF and endothelin 3 regulate migration of enteric neural crest-derived cells via PKA and Rac12013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Cellular Identity of Neurogenic Schwann Cell Precursors2024

Author(s)

Organizer

Data Source

[Presentation] Sox10 suppresses Schwann cell precursor-derived neurogenesis to prevent ectopic autonomic neurons and tumors2023

Author(s)

Organizer

Data Source

ITO KEISUKE 伊藤圭祐

Ito Keisuke 伊藤圭祐

ITO Keisuke 伊藤圭祐