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EMOTO MIHO  江本 美穂

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EMOTO Miho  江本 美穂

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Researcher Number 10578735
Other IDs
Affiliation (Current) 2025: 北海道医療大学, 医療技術学部, 講師
2025: 東京女子医科大学, 医学部, 助教
2025: 札幌医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help 2018 – 2023: 北海道医療大学, 医療技術学部, 講師
2018: 北海道医療大学, その他, 講師
2016 – 2017: 札幌医科大学, 医学部, 研究員
2015: 札幌医科大学, 公私立大学の部局等, 研究員
2011 – 2015: 札幌医科大学, 医療人育成センター, 研究員
2012: 札幌医科大学, 公私立大学の部局等, 研究員
Review Section/Research Field
Principal Investigator
Radiation science / Basic Section 52010:General internal medicine-related
Except Principal Investigator
Basic Section 57050:Prosthodontics-related / Radiation science
Keywords
Principal Investigator
EPRイメージング / 酸化ストレス / 早期発見 / 機械学習 / アルツハイマー病 / 老化 / ナイトロオキサイド化合物 / aging / ROS / 炎症モデルマウス … More / 抗炎症薬 / ナイトロオキサイド / 抗炎症作用 / 抗酸化 / Theranostics / レドックスバランス / EPRイメージング法 / エイジング / アルツハイマー病モデルマウス / 分子イメージング / 酸化還元 / MRI … More
Except Principal Investigator
アルツハイマー型認知症 / 咀嚼 / 口腔機能低下 / 生理機能 / 複数分子 / イメージング / EPR / ESR / 電子常磁性共鳴イメージング Less
  • Research Projects

    (7 results)
  • Research Products

    (89 results)
  • Co-Researchers

    (16 People)
  •  Development of an Early Detection System for Alzheimer's Disease by Machine Learning of EPR ImagingPrincipal Investigator

    • Principal Investigator
      江本 美穂
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  AD発症リスクに口腔機能低下症が及ぼす影響~脳機能イメージングでの検証~

    • Principal Investigator
      川西 克弥
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57050:Prosthodontics-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Evaluation of risk factor under oxidative stress in aging by EPR imagingPrincipal Investigator

    • Principal Investigator
      EMOTO Miho
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Development of novel theranostics probes with EPR imagingPrincipal Investigator

    • Principal Investigator
      EMOTO Miho
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Health Sciences University of Hokkaido
      Sapporo Medical University
  •  Evaluation of oxidative stress in the brain of a mouse model of Alzheimer disease by in vivo EPR imaging system.Principal Investigator

    • Principal Investigator
      Emoto Miho
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  Non-invasive assessment of mouse brain tumor by EPR imagingPrincipal Investigator

    • Principal Investigator
      EMOTO Miho
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  Multiple molecular imaging by EPR spectroscopy

    • Principal Investigator
      FUJII Hirotada
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University

All 2023 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Patent

  • [Journal Article] 研究者の最新動向:アルツハイマー型認知症の発症リスクに口腔機能低下は影響するか2023

    • Author(s)
      川西克弥、江本美穂、豊下祥史、越野寿、藤井博匡、長澤敏行
    • Journal Title

      Precision Medicine

      Volume: 6 Pages: 50-52

    • Data Source
      KAKENHI-PROJECT-22K10062
  • [Journal Article] Effect of relative configuration of TEMPO-type nitroxides on ascorbate reduction2023

    • Author(s)
      Azuma Risa、Yamasaki Toshihide、Emoto Miho C.、Sato-Akaba Hideo、Sano Kohei、Munekane Masayuki、Fujii Hirotada G.、Mukai Takahiro
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 194 Pages: 114-122

    • DOI

      10.1016/j.freeradbiomed.2022.11.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07784, KAKENHI-PROJECT-20K07829, KAKENHI-PROJECT-23K20938, KAKENHI-PROJECT-23K06888
  • [Journal Article] Early detection of redox imbalance in the APPswe/PS1dE9 mouse model of Alzheimer’s disease by in vivo electron paramagnetic resonance imaging2021

    • Author(s)
      Emoto Miho C.、Sato-Akaba Hideo、Hamaue Naoya、Kawanishi Katsuya、Koshino Hisashi、Shimohama Shun、Fujii Hirotada G.
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 172 Pages: 9-18

    • DOI

      10.1016/j.freeradbiomed.2021.05.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07920, KAKENHI-PROJECT-20K07829, KAKENHI-PROJECT-23K20938
  • [Journal Article] Three-dimensional electron paramagnetic resonance imaging of mice using ascorbic acid sensitive nitroxide imaging probes2021

    • Author(s)
      Sato-Akaba Hideo、Emoto Miho C.、Yamada Ken-ichi、Koshino Hisashi、Fujii Hirotada G.
    • Journal Title

      Free Radical Research

      Volume: 55 Issue: 9-10 Pages: 950-957

    • DOI

      10.1080/10715762.2021.1991918

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07920, KAKENHI-PROJECT-20K07829, KAKENHI-PROJECT-23K20938
  • [Journal Article] Design and Fabrication of Compact Arrayed Magnet for Biological EPR Imaging2020

    • Author(s)
      Sato-Akaba Hideo、Okada Yuki、Tsuji Kentaro、Emoto Miho C.、Fujii Hirotada G.
    • Journal Title

      Applied Magnetic Resonance

      Volume: - Issue: 8 Pages: 1-13

    • DOI

      10.1007/s00723-020-01256-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07920, KAKENHI-PROJECT-20K07829, KAKENHI-PROJECT-18K04164
  • [Journal Article] Brain Redox Imaging Using In Vivo Electron Paramagnetic Resonance Imaging and Nitroxide Imaging Probes2019

    • Author(s)
      Fujii Hirotada、Emoto Miho、Sato-Akaba Hideo
    • Journal Title

      Magnetochemistry

      Volume: 5 Issue: 1 Pages: 11-11

    • DOI

      10.3390/magnetochemistry5010011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K04164, KAKENHI-PROJECT-16K10291
  • [Journal Article] Early administration of galantamine from preplaque phase suppresses oxidative stress and improves cognitive behavior in APPswe/PS1dE9 mouse model of Alzheimer's disease2019

    • Author(s)
      Saito Taro、Hisahara Shin、Iwahara Naotoshi、Emoto Miho C.、Yokokawa Kazuki、Suzuki Hiromi、Manabe Tatsuo、Matsumura Akihiro、Suzuki Syuuichirou、Matsushita Takashi、Kawamata Jun、Sato-Akaba Hideo、Fujii Hirotada G.、Shimohama Shun
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 145 Pages: 20-32

    • DOI

      10.1016/j.freeradbiomed.2019.09.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07920, KAKENHI-PROJECT-17K07099, KAKENHI-PROJECT-16K19776, KAKENHI-PROJECT-17K16388
  • [Journal Article] Transplantation of Mesenchymal Stem Cells Improves Amyloid-β Pathology by Modifying Microglial Function and Suppressing Oxidative Stress2019

    • Author(s)
      Yokokawa Kazuki、Iwahara Naotoshi、Hisahara Shin、Emoto Miho C.、Saito Taro、Suzuki Hiromi、Manabe Tatsuo、Matsumura Akihiro、Matsushita Takashi、Suzuki Syuuichirou、Kawamata Jun、Sato-Akaba Hideo、Fujii Hirotada G.、Shimohama Shun
    • Journal Title

      Journal of Alzheimer's Disease

      Volume: 72 Issue: 3 Pages: 867-884

    • DOI

      10.3233/jad-190817

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07920, KAKENHI-PROJECT-17K07099, KAKENHI-PROJECT-16K19776, KAKENHI-PROJECT-17K16388
  • [Journal Article] Evaluation of Mitochondrial Oxidative Stress in the Brain of a Transgenic Mouse Model of Alzheimer's Disease by in vitro Electron Paramagnetic Resonance Spectroscopy.2019

    • Author(s)
      Manabe T, Matsumura A, Yokokawa K, Saito T, Fujikura M, Iwahara N, Matsushita T, Suzuki S, Hisahara S, Kawamata J, Suzuki H, Emoto MC, Fujii HG, Shimohama S.
    • Journal Title

      Journal of Alzheimer's disease

      Volume: 67 Issue: 3 Pages: 1079-1087

    • DOI

      10.3233/jad-180985

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19776, KAKENHI-PROJECT-16H05279, KAKENHI-PROJECT-16K10291, KAKENHI-PROJECT-17K07099, KAKENHI-PROJECT-17K16388
  • [Journal Article] Effect of Glutathione and Ascorbic Acid on the Brain Redox Status in Transgenic Mouse Model of Alzheimer’s Disease Evaluated by EPR Imaging2019

    • Author(s)
      Miho C Emoto, Naoya Hamaue, Hideo Sato-Akaba, Hirotada G Fujii
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 145 Pages: S100-S101

    • DOI

      10.1016/j.freeradbiomed.2019.10.268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07920
  • [Journal Article] Non-invasive mapping of glutathione levels in mouse brains by in vivo electron paramagnetic resonance (EPR) imaging: Applied to a kindling mouse model2019

    • Author(s)
      Emoto Miho C.、Sato-Akaba Hideo、Matsuoka Yuta、Yamada Ken-ichi、Fujii Hirotada G.
    • Journal Title

      Neuroscience Letters

      Volume: 690 Pages: 6-10

    • DOI

      10.1016/j.neulet.2018.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K04164, KAKENHI-PROJECT-18K14884, KAKENHI-PROJECT-17H03977, KAKENHI-PROJECT-16K10291
  • [Journal Article] Synthesis and Evaluation as a Blood–Brain Barrier-Permeable Probe of 7-<i>N</i>-(PROXYL-3-yl-methyl)theophylline2018

    • Author(s)
      Emoto Miho C.、Sasaki Kota、Maeda Koya、Fujii Hirotada G.、Sato Shingo
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 66 Issue: 9 Pages: 887-891

    • DOI

      10.1248/cpb.c18-00333

    • NAID

      130007479637

    • ISSN
      0009-2363, 1347-5223
    • Year and Date
      2018-09-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Journal Article] Non-invasive imaging of the levels and effects of glutathione on the redox status of mouse brain using electron paramagnetic resonance imaging2017

    • Author(s)
      Miho C. Emoto, Yuta Matsuoka, Ken-ichi Yamada, Hideo Sato-Akaba, Hirotada G. Fujii
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 485 Issue: 4 Pages: 802-806

    • DOI

      10.1016/j.bbrc.2017.02.134

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H07047, KAKENHI-PROJECT-26293280, KAKENHI-PROJECT-16K10291, KAKENHI-PROJECT-16K15109
  • [Journal Article] Design and testing of a 750MHz CW-EPR digital console for small animal imaging.2017

    • Author(s)
      Sato-Akaba H, Emoto MC, Hirata H, Fujii HG
    • Journal Title

      J Magn Reson.

      Volume: 284 Pages: 48-58

    • DOI

      10.1016/j.jmr.2017.09.008

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10291, KAKENHI-PROJECT-16K14275
  • [Journal Article] Novel blood-brain-barrier-permeable spin probe for in vivo electron paramagnetic resonance imaging2016

    • Author(s)
      X. Wang, M. Emoto, Y. Miyake, K. Itto, S. Xu, H. Fujii, H. Hirata, H. Arimoto,
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 26 Issue: 20 Pages: 4947-4949

    • DOI

      10.1016/j.bmcl.2016.09.010

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462841, KAKENHI-PROJECT-16K10291
  • [Journal Article] In Vivo Brain Redox Status in Diethylmaleate-Treated Mice Using EPR Imaging.2016

    • Author(s)
      Hirotada G Fujii, Miho C Emoto, Yuta Matsuoka, Ken-ichi Yamada
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 100 Pages: S161-S161

    • DOI

      10.1016/j.freeradbiomed.2016.10.421

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Journal Article] Development of nitroxide-based theranostic compounds that act both as anti-inflammatory drugs and brain redox imaging probes in MRI2016

    • Author(s)
      Emoto MC, Sato S, Fujii HG
    • Journal Title

      Magnetic Resonance in Chemistry

      Volume: 54 Issue: 9 Pages: 705-711

    • DOI

      10.1002/mrc.4431

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15458, KAKENHI-PROJECT-16K10291
  • [Journal Article] Evaluation of oxidative stress in the brain of a transgenic mouse model of Alzheimer disease by in vivo electron paramagnetic resonance imaging.2015

    • Author(s)
      Matsumura A, Emoto MC, Suzuki S, Iwahara N, Hisahara S, Kawamata J, Suzuki H,Yamauchi A, Sato-Akaba H, Fujii HG, Shimohama S.
    • Journal Title

      Free Radic Biol Med.

      Volume: 85 Pages: 165-173

    • DOI

      10.1016/j.freeradbiomed.2015.04.013

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09840, KAKENHI-PROJECT-15K19288, KAKENHI-PROJECT-26861008
  • [Journal Article] Brain redox imaging in the pentylenetetrazole (PTZ)-induced kindling model of epilepsy by using in vivo electron paramagnetic resonance and a nitroxide imaging probe.2015

    • Author(s)
      Emoto CM, Yamato M, Sato-Akaba H, Yamada K, Fujii GH.
    • Journal Title

      Neuroscience Letters

      Volume: 608 Pages: 40-44

    • DOI

      10.1016/j.neulet.2015.10.008

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15458, KAKENHI-PROJECT-26861008, KAKENHI-PROJECT-26293280
  • [Journal Article] Brain imaging in methamphetamine-treated mice using a nitroxide contrast agent for EPR imaging of the redox status and a gadolinium contrast agent for MRI observation of blood-brain barrier function.2015

    • Author(s)
      Emoto MC, Yamato M, Sato-Akaba H, Yamada K, Matsuoka Y, Fujii HG.
    • Journal Title

      Free Radical Research

      Volume: 49 Issue: 8 Pages: 1038-1047

    • DOI

      10.3109/10715762.2015.1040787

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26861008
  • [Journal Article] The Effect of Aging for Oxidative Stress in Mouse Brains by EPR Imaging Method.2014

    • Author(s)
      Miho C Emoto, Akihiro Matsumura, Hiromi Suzuki, Shun Shimohama, Hirotada G Fujii.
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 76 Pages: S22-S23

    • DOI

      10.1016/j.freeradbiomed.2014.10.472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26861008
  • [Journal Article] Synthesis of ^<15>N-labeled 4-oxo-2,2, 6,6-tetraethylpiperidine nitroxide for EPR brain imaging2014

    • Author(s)
      Xiaolei Wang, Miho Emoto, Atsushi Sugimoto, Yusuke Miyake, Kaori Itto, Mitsuo Amasaka, Shu Xu, Hiroshi Hirata, Hirotada Fuji, Hirokazu Arimoto
    • Journal Title

      Tetrahedron Letters

      Volume: 55 Issue: 13 Pages: 2146-2149

    • DOI

      10.1016/j.tetlet.2014.02.063

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07152, KAKENHI-PROJECT-26861008
  • [Journal Article] Dynamic changes in the distribution and time course of blood-brain barrier-permeative nitroxides in the mouse head with EPR imaging: visualization of blood flow in a mouse model of ischemia.2014

    • Author(s)
      Emoto MC, Sato-Akaba H, Hirata H, Fujii HG.
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 74 Pages: 222-228

    • DOI

      10.1016/j.freeradbiomed.2014.06.026

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26861008
  • [Journal Article] Novel ascorbic acid-resistive nitroxide in a lipid emulsion: An efficient brain imaging contrast agent for MRI of small rodents2013

    • Author(s)
      Emoto CM, Yamada K, Yamato M, Fujii GH
    • Journal Title

      Neuroscience Letters

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Journal Article] Redox map of mouse brain by three-dimensional EPR imaging with six-membered nitroxyl radicals.2013

    • Author(s)
      MC Emoto, H Sato-Akaba, H Hirata, HG Fujii
    • Journal Title

      Proc.Intl.Soc.Mag.Reson.Med.

      Volume: 21 Pages: 1986-1986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] Redox Mapping in LPS-Treated Mouse Brain by Using Three-Dimensional EPR Imaging System2013

    • Author(s)
      Miho C Emoto, Hideo Sato-Akaba, Hiroshi Hirata, and Hirotada G Fujii
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 65 Pages: S45-S45

    • DOI

      10.1016/j.freeradbiomed.2013.10.495

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] Noninvasive mapping of the redox status in septic mouse by in vivoelectron paramagnetic resonance imaging2013

    • Author(s)
      FujiiHG, Sato-AkabaH, EmotoMC, ItohK, IshiharaY, HirataH
    • Journal Title

      Magn Reson Imag

      Volume: 31 Pages: 130-138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Journal Article] Novel ascorbic acid-resistive nitroxide in a lipid emulsion: An efficient brain imaging contrast agent for MRI of small rodents.2013

    • Author(s)
      Emoto MC, Yamada KI, Yamato M, Fujii HG.
    • Journal Title

      Neurosci Lett.

      Volume: 546 Pages: 11-15

    • DOI

      10.1016/j.neulet.2013.04.044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390011, KAKENHI-PROJECT-24791318, KAKENHI-PROJECT-25670537
  • [Journal Article] Redox Mapping in LPS-Treated Mouse Brain by Using Three-Dimensional EPR Imaging System2013

    • Author(s)
      Miho C Emoto, Hideo Sato-Akaba, Hiroshi Hirata, and Hirotada G Fujii
    • Journal Title

      Free Radical Biology and Medicine

      Volume: s45 Pages: IFC-IFC

    • DOI

      10.1016/s0891-5849(12)01715-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] Brain Redox Mapping in Methanphetamine-treated Mice using Tree-Dimensional EPR Imaging2013

    • Author(s)
      HG Fujii, MC Emoto, M Yamato, KI Yamada
    • Journal Title

      Proc.Intl.Soc.Mag.Reson.Med

      Volume: 21 Pages: 1987-1987

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] Noninvasive mapping of the redox status in septic mouse by in vivo electron paramagnetic resonance imaging.2013

    • Author(s)
      Hirotada Fujii
    • Journal Title

      Magnetic Resonance Imaging

      Volume: 31 Issue: 1 Pages: 130-138

    • DOI

      10.1016/j.mri.2012.06.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390236, KAKENHI-PROJECT-23659592, KAKENHI-PROJECT-24791318, KAKENHI-PROJECT-25340047
  • [Journal Article] Redox map of mouse brain by three-dimensional EPR imaging with six-membered nitroxyl radicals2013

    • Author(s)
      MC Emoto, H Sato-Akaba, H Hirata, HG Fujii
    • Journal Title

      Proc. Intl. Soc. Mag. Reson. Med

      Volume: 21 Pages: 1986-1986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] Distribution and time course of Blood-Brain Barrier-permeable nitroxides in mouse head by MRI and EPR imaging2012

    • Author(s)
      MC Emoto, H Sato-Akaba, H Hirata, HG Fujii
    • Journal Title

      Proc. Intl. Soc. Mag. Reson. Med

      Volume: 20 Pages: 1709-1709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] EPR&ndash;MRI studies of small rodents by the use of paramagnetic compounds2012

    • Author(s)
      Fujii H, Emoto M
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 140 Issue: 4 Pages: 156-160

    • DOI

      10.1254/fpj.140.156

    • NAID

      10031072208

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] Magnetic Resonance-based molecular imaging studies of mice by using paramagnetic contrast probes2012

    • Author(s)
      Hirotada Fujii, Miho Emoto
    • Journal Title

      Journal of Pharmacological Science

      Volume: 118 Pages: 16-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] Differences in Distribution and Reducton Rate of BBB Permeable Nitorixides by in Vivo EPR Imaging Method2012

    • Author(s)
      Miho C Emoto, Hideo Sato-Akaba, Hiroshi Hirata, and Hirotada G Fujii
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] Distribution and time course of Blood Brain Barrier-permeable nitroxides in mouse head by MRI and EPR imaging2012

    • Author(s)
      Miho C Emoto, Hideo Sato-Akaba, Hiroshi Hirata, and Hirotada G Fujii
    • Journal Title

      Proc.Intl.Soc.Mag.Reson.Med.

      Volume: 20 Pages: 1709-1709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] Difference in distribution and reduction rate of BBB permeable nitroxides by in vivo EPR imaging method2012

    • Author(s)
      MC Emoto, H Sato-Akaba, H Hirata, HG Fujii
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 53 Pages: S65-S65

    • DOI

      10.1016/j.freeradbiomed.2012.10.195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Journal Article] A novel ascorbic acid-resistive nitroxide in fat emulsion is an effective2011

    • Author(s)
      Emoto, M., Fujii, H.
    • Journal Title

      Free Radical Research

      Volume: 45 Issue: 11-12 Pages: 1325-1332

    • DOI

      10.3109/10715762.2011.618499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390236, KAKENHI-PROJECT-23659592
  • [Journal Article] Anovel ascorbic acid-resistant nitroxide in fat emulsion is an efficient brainimaging probe for in vivo EPR imaging of mouse2011

    • Author(s)
      Emoto M, Mito F, Yamasaki T, Yamada K, Sato-Akaba H, Hirata H,Fujii H
    • Journal Title

      Free Radic Res

      Volume: 45 Pages: 1325-1332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Patent] 電子スピン共鳴装置2017

    • Inventor(s)
      赤羽英夫、藤井博匡、江本美穂
    • Industrial Property Rights Holder
      赤羽英夫、藤井博匡、江本美穂
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-050576
    • Filing Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] 病態解明に向けたEPR法によるマウス脳内酸化ストレス状態のイメージング研究2023

    • Author(s)
      江本美穂
    • Organizer
      第62回電子スピンサイエンス学会
    • Data Source
      KAKENHI-PROJECT-23K06888
  • [Presentation] Brain imaging of small animals by compact bench-top EPR imager.2021

    • Author(s)
      Hirotada G Fujii, Hideo Sato-Akaba, Miho C Emoto
    • Organizer
      ISMAR-APNMR-NMRSJ-SEST2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07920
  • [Presentation] Brain redox status of Alzheimer's disease model mouse using piperidine nitroxide Tempone with EPR imaging system2021

    • Author(s)
      Emoto Miho, Sato-Akaba H, Fujii H
    • Organizer
      第49回日本磁気共鳴医学会大会
    • Data Source
      KAKENHI-PROJECT-19K07920
  • [Presentation] Development of digital EPR imaging system for biological applications.2021

    • Author(s)
      Hideo Sato-Akaba, Miho C. Emoto, Hirotada G. Fujii
    • Organizer
      ISMAR-APNMR-NMRSJ-SEST2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07920
  • [Presentation] Effect of Glutathione and Ascorbic Acid on the Brain Redox Status in Transgenic Mouse Model of Alzheimer’s Disease Evaluated by EPR Imaging2019

    • Author(s)
      Miho C Emoto, Naoya Hamaue, Hideo Sato-Akaba, Hirotada G Fujii
    • Organizer
      The Society for Redox Biology and Medicine's 26th Annual Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07920
  • [Presentation] アルツハイマー病モデルマウスを用いた脳内酸化ストレスのイメージング研究2019

    • Author(s)
      江本美穂
    • Organizer
      第72回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07920
  • [Presentation] Brain redox imaging using blood-brain barrier-permeable nitroxide probes with different lipophilicity2019

    • Author(s)
      Emoto Miho, Sato S, Sato-Akaba H, Fujii H
    • Organizer
      第47回日本磁気共鳴医学会大会
    • Data Source
      KAKENHI-PROJECT-19K07920
  • [Presentation] EPRイメージング法によるグルタチオンマッピング:神経疾患動物への応用を目指して2018

    • Author(s)
      藤井博匡、江本美穂、赤羽英夫、松岡悠太、山田健一
    • Organizer
      第57回電子スピンサイエンス学会年会
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] Non-invasive mapping of glutathione levels in mouse brains by electron paramagnetic resonance (EPR) imaging.2018

    • Author(s)
      Hirotada Fujii, Miho Emoto, Yuta Matsuoka, Ken-ichi Yamada, Hideo Sato-Akaba.
    • Organizer
      JOINT ANNUAL MEETING ISMRM-ESMRMB
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] EPRイメージング法による脳内グルタチオンのマッピング2018

    • Author(s)
      Hirotada Fujii, Miho Emoto, Yuta Matsuoka, Ken-ichi Yamada, Hideo Sato-Akaba
    • Organizer
      第46回日本磁気共鳴医学会大会
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] Non-invasive mapping of glutathione levels in mouse brains by electron paramagnetic resonance (EPR) imaging.2018

    • Author(s)
      Hirotada Fujii, Miho Emoto, Yuta Matsuoka, Ken-ichi Yamada, Hideo Sato-Akaba.
    • Organizer
      JOINT ANNUAL MEETING ISMRM-ESMRMB 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] EPRイメージング負を用いたマウス脳内酸化ストレス状態の加齢による影響の可視化2018

    • Author(s)
      Miho Emoto, Hideo Akaba-Sato, Hirotada Fujii
    • Organizer
      第46回日本磁気共鳴医学会大会
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] 骨髄慣用系幹細胞によるアルツハイマー病治療における脳内酸化ストレス動態の検討2017

    • Author(s)
      横川和樹、岩原直敏、江本美穂、久原真、齋藤太郎、藤倉舞、眞部建郎、鈴木紘美、松下隆司、松村晃寛、鈴木秀一郎、川又純、藤井博匡、下濱俊
    • Organizer
      第36回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] Molecular imaging of glutathione in mouse brain 脳内グルタチオンの分子イメージング2017

    • Author(s)
      Hirotada Fujii, Miho Emoto, Yuta Matsuoka, Ken-ichi Yamada, Hideo Sato-Akaba
    • Organizer
      第45回日本磁気共鳴医学会大会
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] Brain redox imaging using blood-brain-barrier nitroxides by digital EPR imaging system2017

    • Author(s)
      M.C. Emoto, Hideo Sato-Akaba, H.G. Fujii
    • Organizer
      第25回国際磁気共鳴医学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] Does Tempol enter the brain with an unpaired electron?2016

    • Author(s)
      M.C. Emoto, Hideo Sato-Akaba, H.G. Fujii
    • Organizer
      第24回国際磁気共鳴医学会
    • Place of Presentation
      シンガポール
    • Year and Date
      2016-05-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] Development of nitroxide-based theranostics probe for brain research by MRI2016

    • Author(s)
      M.C. Emoto, S Sato, H.G. Fujii
    • Organizer
      第24回国際磁気共鳴医学会
    • Place of Presentation
      シンガポール
    • Year and Date
      2016-05-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] Bain Redox imaging using nitroxide-based theranostic Probes in septic mice2016

    • Author(s)
      FUJII G Hirotada, EMOTO C Miho, SATO Shingo
    • Organizer
      第17回International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants
    • Place of Presentation
      パリ(フランス)
    • Year and Date
      2016-06-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] n Vivo Brain Redox Status in Diethylmaleate-Treated Mice Using EPR Imaging2016

    • Author(s)
      Hirotada G Fujii, Miho C Emoto, Yuta Matsuoka, Ken-ichi Yamada
    • Organizer
      SfRBM's 23rd Annual Meeting
    • Place of Presentation
      サンフランシスコ(USA)
    • Year and Date
      2016-11-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] マウス脳内REDOXイメージング用Theranosticsプローブの開発2016

    • Author(s)
      藤井博匡、江本美穂、佐藤慎吾
    • Organizer
      第44回日本磁気共鳴医学会大会
    • Place of Presentation
      大宮ソニックシティ(埼玉県さいたま市)
    • Year and Date
      2016-09-09
    • Data Source
      KAKENHI-PROJECT-16K10291
  • [Presentation] 抗炎症薬とニトロキシド化合物によるTheranosticsイメージングプローブの開発2015

    • Author(s)
      江本美穂、佐藤慎吾、藤井博匡
    • Organizer
      第43回日本磁気共鳴医学会大会
    • Place of Presentation
      東京ドームホテル(東京都文京区)
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-26861008
  • [Presentation] Novel theranostics work as therapeuic drug and imaging probe for MRI and EPR imaging2015

    • Author(s)
      M.C. Emoto, S Sato, H.G. Fujii
    • Organizer
      ESMRMB2015
    • Place of Presentation
      エジンバラ、イギリス
    • Year and Date
      2015-10-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26861008
  • [Presentation] Development of Theranostics Imaging Probe for MRI and EPR Imaging2015

    • Author(s)
      Emoto Miho, Sato Shingo, Fujii Hirotada G.
    • Organizer
      第23回国際磁気共鳴医学会
    • Place of Presentation
      トロント、カナダ
    • Year and Date
      2015-05-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26861008
  • [Presentation] 血液脳関門透過性 nitroxide を用いたマウス頭部の高速EPR イメージングとMRI2013

    • Author(s)
      江本美穂・赤羽英夫・平田拓・藤井博匡
    • Organizer
      電子スピンサイエンス学会
    • Place of Presentation
      大宮ソニックシティ
    • Year and Date
      2013-10-24
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] 高速EPRイメージング法を用いた酸化ストレスを可視化する分子イメージング手法の開発2013

    • Author(s)
      江本美穂・赤羽英夫・平田拓・藤井博匡
    • Organizer
      日本磁気共鳴医学会
    • Place of Presentation
      アスティ徳島
    • Year and Date
      2013-09-19
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] Redox map of mouse brain by three-dimensional EPR imaging with six-membered nitroxyl radicals2013

    • Author(s)
      MC Emoto, H Sato-Akaba, H Hirata, HG Fujii
    • Organizer
      国際磁気共鳴医学会
    • Place of Presentation
      ソルトレイクシティー アメリカ合衆国
    • Year and Date
      2013-04-25
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] Brain redox mapping in methamphetamine-treated mice using three-dimensional EPR imaging2013

    • Author(s)
      Hirotada Fujii, Miho Emoto, Mayumi Yamato, Ken-ichi Yamada
    • Organizer
      ISMRM2013
    • Place of Presentation
      Salt-lake city
    • Year and Date
      2013-04-25
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Presentation] Redox map of mouse brain by three-dimensional EPR imaging with six-membered nitroxyl radicals.2013

    • Author(s)
      MC Emoto, H Sato-Akaba, H Hirata, HG Fujii.
    • Organizer
      The International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Salt Palace Convention Center
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] Redox Mapping in LPS-Treated Mouse Brain byUsing Three-Dimensional EPR Imaging System2013

    • Author(s)
      Miho C Emoto, Hideo Sato-Akaba, Hiroshi Hirata, and Hirotada G Fujii
    • Organizer
      フリーラジカル生物医学会議
    • Place of Presentation
      サンアントニオ アメリカ合衆国
    • Year and Date
      2013-11-21
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] Redox map of mouse brain by three-dimensional EPR imaging with six-membered nitroxyl radicals2013

    • Author(s)
      Miho Emoto, Hideo Sato-Akaba, Hiroshi Hirata, Hirotada Fujii
    • Organizer
      ISMRM2013
    • Place of Presentation
      Salt-lake city
    • Year and Date
      2013-04-25
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Presentation] In vivo Imaging of Redox Status and Blood Brain Barrier Function in Methamphetamine-Treated Mouse Brain2013

    • Author(s)
      Hirotada G Fujii, Miho C Emoto, Mayumi Yamato, and Ken-ichi Yamada
    • Organizer
      The Society for Free Radical Biology and Medicine
    • Place of Presentation
      Grand Hyatt San Antonio
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] Brain Redox Mapping in Methanphetamine-treated Mice using Tree-Dimensional EPR Imaging2013

    • Author(s)
      HG Fujii, MC Emoto, M Yamato, KI Yamada.
    • Organizer
      The International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Salt Palace Convention Center
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] Redox Mapping in LPS-Treated Mouse Brain by Using Three-Dimensional EPR Imaging System2013

    • Author(s)
      Miho C Emoto, Hideo Sato-Akaba, Hiroshi Hirata, and Hirotada G Fujii
    • Organizer
      The Society for Free Radical Biology and Medicine
    • Place of Presentation
      Grand Hyatt San Antonio
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] 高速EPRイメージング法を用いた酸化ストレスを可視化する分子イメージング手法の開発2013

    • Author(s)
      江本美穂、赤羽英夫、平田拓、藤井博匡
    • Organizer
      日本磁気共鳴医学会
    • Place of Presentation
      アスティとくしま
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] Distribution and time course of Blood Brain Barrier-permeable nitroxides in mouse head by MRI and EPR imaging2012

    • Author(s)
      Miho C Emoto, Hideo Sato-Akaba, Hiroshi Hirata, and Hirotada G Fujii
    • Organizer
      The International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      メルボルンコンベンションセンター
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] Differences in distribution and reduction rate of BBB permeable nitroxides by in vivo EPR imaging method2012

    • Author(s)
      Miho Emoto, Hideo Sato-Akaba, Hiroshi Hirata, Hirotada Fujii
    • Organizer
      SFRBM2012
    • Place of Presentation
      San Antonio
    • Year and Date
      2012-11-20
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Presentation] Differences in Distribution and Reducton Rate of BBB Permeable Nitorixides by in Vivo EPR Imaging Method2012

    • Author(s)
      Miho C Emoto, Hideo Sato-Akaba, Hiroshi Hirata, and Hirotada G Fujii
    • Organizer
      Society of Free Radical Biology and Medicine
    • Place of Presentation
      Hilton San Diego Bayfront
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] EPRイメージングによる六員環ニトロキシドのマウス頭部における酸化還元状態の評価2012

    • Author(s)
      江本美穂、赤羽英夫、平田拓、藤井博匡
    • Organizer
      SEST2012
    • Place of Presentation
      札幌市
    • Year and Date
      2012-11-01
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Presentation] グルコースTempoスピンプローブを用いたEPRイメージング2012

    • Author(s)
      藤井博匡、佐藤慎吾、江本美穂、平田拓
    • Organizer
      SEST2012
    • Place of Presentation
      札幌市
    • Year and Date
      2012-11-01
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Presentation] Distribution and time course of Blood-Brain Barrier-permeable nitroxides in mouse head by MRI and EPR imaging2012

    • Author(s)
      MC Emoto, H Sato-Akaba, H Hirata, HG Fujii
    • Organizer
      国際磁気共鳴医学会
    • Place of Presentation
      メルボルン オーストラリア
    • Year and Date
      2012-05-08
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] EPR イメージングによる六員環ニトロキシドのマウス頭部における酸化還元状態の評価2012

    • Author(s)
      江本美穂・赤羽英夫・平田拓・藤井博匡
    • Organizer
      電子スピンサイエンス学会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2012-11-03
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] EPRイメージングによる六員環ニトロキシドのマウス頭部における酸化還元状態の評価2012

    • Author(s)
      江本美穂、赤羽英夫、平田拓、藤井博匡
    • Organizer
      電子スピンサイエンス学会
    • Place of Presentation
      札幌コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-24791318
  • [Presentation] Novel ascorbic acid-resistive nitroxides in fat emulsion: An efficient brain imaging probe for MRI of small rodents2012

    • Author(s)
      HirotadaFujii, Miho Emoto, Mayumi Yamato, Ken-ichi Yamada
    • Organizer
      SFRBM2012
    • Place of Presentation
      2012, San Antonio
    • Year and Date
      2012-11-20
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Presentation] 新規アスコルビン酸耐性ニトロキシドによるマウス頭部のin vivo EPRイメージング2011

    • Author(s)
      江本美穂、水戸文弥、山崎俊栄、山田健一、赤羽英夫、平田拓、藤井博匡
    • Organizer
      SEST2011
    • Place of Presentation
      仙台市
    • Year and Date
      2011-11-17
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Presentation] 高速EPRイメージングシステムによるマウス脳内レドックス状態の評価について2011

    • Author(s)
      藤井博匡、江本美穂、赤羽英夫、平田拓
    • Organizer
      SEST2011
    • Place of Presentation
      仙台市
    • Year and Date
      2011-11-17
    • Data Source
      KAKENHI-PROJECT-23659592
  • [Presentation] MRIを用いたアスコルビン酸耐性ニトロキシド化合物TEEPONEのマウス頭部における動態解析

    • Author(s)
      江本美穂、山田健一、大和真由美、藤井博匡
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-09-18 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-26861008
  • [Presentation] Co-registered EPR and MRI of the mouse head indicates detailed distributions of piperidine nitroxides.

    • Author(s)
      MC Emoto, H Sato-Akaba, H Hirata, HG Fujii.
    • Organizer
      第22回国際磁気共鳴医学会
    • Place of Presentation
      ミラノ・イタリア
    • Year and Date
      2014-05-10 – 2014-05-16
    • Data Source
      KAKENHI-PROJECT-26861008
  • [Presentation] The Effect of Aging for Oxidative Stress in Mouse Brains by EPR Imaging Method.

    • Author(s)
      Miho C Emoto, Akihiro Matsumura, Hiromi Suzuki, Shun Shimohama, And Hirotada G Fujii.
    • Organizer
      第21回米国フリーラジカル生物医学会議
    • Place of Presentation
      シアトル・アメリカ合衆国
    • Year and Date
      2014-11-19 – 2014-11-23
    • Data Source
      KAKENHI-PROJECT-26861008
  • 1.  FUJII Hirotada (70209013)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 31 results
  • 2.  川西 克弥 (10438377)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  豊下 祥史 (20399900)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  越野 寿 (90186669)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  長澤 敏行 (90262203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  加藤 千恵次 (10292012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SATO Shingo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 8.  AKABA Hideo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 9.  川又 純
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  下濱 俊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  山田 健一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  三宅 実
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  平田 拓
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  岩原 直敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  松岡 悠太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  山崎 俊栄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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