Kitamura Akira 北村朗

… Alternative Names

KITAMURA Akira 北村朗

北村朗キタムラアキラ

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Researcher Number	10580152
Other IDs	https://orcid.org/0000-0001-8357-8593
External Links
Affiliation (Current)	2024: 北海道大学, 先端生命科学研究院, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 北海道大学, 先端生命科学研究院, 講師 2018 – 2020: 北海道大学, 先端生命科学研究院, 講師 2016 – 2017: 北海道大学, 先端生命科学研究院, 助教 2011 – 2016: 北海道大学, 先端生命科学研究科(研究院), 助教 2013: 北海道大学, 先端生命科学研究院, 助教 … More 2011: 北海道大学, 大学院・先端生命科学研究院, 助教 2008 – 2009: Hokkaido University, 大学院・先端生命科学研究院, 特別研究員(PD) 2007: Kyoto University, 大学院・理学研究科, 特別研究員DC2 2006: 京都大学, 大学院理学研究科, 特別研究員DC2 Less
Review Section/Research Field	Principal Investigator Cell biology / Cell biology / Transformative Research Areas, Section (III) / Complex systems / Basic Section 44010:Cell biology-related Except Principal Investigator Basic Section 43040:Biophysics-related / Medium-sized Section 90:Biomedical engineering and related fields / Cell biology / Nanomaterials/Nanobioscience / Biological Sciences
Keywords	Principal Investigator 蛍光相関分光法 / RNA / 神経変性疾患 / タンパク質凝集体 / 筋萎縮性側索硬化症 / ALS / TDP-43 / SOD1 / 分子シャペロン / 線虫 … More / タンパク質恒常性 / FRAP / TDP43 / 蛍光 / タンパク質 / クラスター / ユビキチン / プロテアソーム / 分光イメージング手法 / タンパク質品質管理機構 / マススペクトル / タンパク質分解 / 筋委縮性側索硬化症 / RNAi / ポリグルタミン病 / CCT / シャペロニン / 脱凝集 / 凝集体 / fALS / 生細胞イメージング / 熱力学的安定性 / 蛍光測定 / タンパク質凝集 / リコンビナントタンパク質 / RNA-タンパク質相互作用 / FCCS / CD / 蛍光寿命イメージング顕微鏡 / TRAST分光法 / 浸透圧ストレス / ストレス顆粒 / タンパク質封入体 / TDP-25 / FCS / 分子動態解析 / 拡散 / 封入体 / FRET / 細胞質封入体 / タンパク質品質管理 / 蛍光分光イメージング / 神経細胞死 / RNA結合タンパク質 / 細胞内封入体 … More Except Principal Investigator 相関関数 / タンパク質相互作用 / 蛍光測定 / 生物物理 / 並進拡散運動 / 偏光測定 / ２量体形成 / 回転拡散測定 / 情報伝達 / 蛍光相関分光法 / 偏光 / 併進拡散運動 / 回転拡散運動 / 相関分光 / 散乱測定 / 蛍光微粒子 / 微粒子 / 光散乱測定 / ATP / 基質特異性 / 機能制御 / 構造変化 / 反応サイクル / HSP60 / CCT / ATPase / 複合体形成 / フォールディング / 分子シャペロン / 空間光位相変調 / 空間相関 / 時間相関 / シグナル伝達 / 細胞・組織 / 可視化 / 1分子計測 / 分布関数 / タンパク質凝集体 / シャペロン / 蛍光相互相関分析 / 1分子検出 / 酵母プリオン / 凝集タンパク質 / 一分子検出 / 分子集合体 / 生体分子 Less

Establishing extreme spatio-temporal correlation spectroscopy for biological cluster analysisPrincipal Investigator
- Principal Investigator
  
  北村朗
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Hokkaido University
蛍光動的消光測定による生細胞内RNA立体構造の情報物理解析Principal Investigator
- Principal Investigator
  
  北村朗
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hokkaido University
細胞由来微粒子迅速測定のための蛍光と散乱光測定の融合
- Principal Investigator
  
  金城政孝
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Hokkaido University
タンパク質2量体安定化機構へ与える細胞内微環境の影響解明
- Principal Investigator
  
  金城政孝
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Hokkaido University
Elucidation for chaperone RNAs that prevent protein aggregation associated with neurodegenerative diseases.Principal Investigator
- Principal Investigator
  
  Kitamura Akira
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Hokkaido University
Elucidation for the regulation of motility and lifespan by proteostasis(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Kitamura Akira
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Cell biology
- Research Institution
  Hokkaido University
Establishment of unified theory of cellular inclusion bodies including misfolded proteinPrincipal Investigator
- Principal Investigator
  
  Kitamura Akira
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Hokkaido University
Regulation of cellular functions by highly evolved two chaperonins
- Principal Investigator
  
  KUBOTA HIROSHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Akita University
Analysis of neuronal cell death by ALS-associated misfolded protein aggregation with modulation of cellular RNA homeostasisPrincipal Investigator
- Principal Investigator
  
  KITAMURA Akira
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Hokkaido University
多点時空間相関解析法による細胞内分子複合体研究
- Principal Investigator
  
  金城政孝
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Hokkaido University
神経変性疾患を引き起こすタンパク質凝集体形成と神経細胞死機構の時空間的解析Principal Investigator
- Principal Investigator
  
  北村朗
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Cell biology
- Research Institution
  Hokkaido University
Study of membrane binding protein complex using total internal reflection fluorescence correlation spectroscopy
- Principal Investigator
  
  KINJO Masataka
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
細胞質シャペロニンの機能解析Principal Investigator
- Principal Investigator
  
  北村朗
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University

[Book] 阪大･北大コースブック「新・生細胞蛍光イメージング」第21章2015
- Author(s)
  北村朗，白燦基，金城政孝
- Total Pages
  340
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-26440090
[Book] 阪大･北大コースブック「新・生細胞蛍光イメージング」実習８－２2015
- Author(s)
  北村朗，白燦基，金城政孝
- Total Pages
  340
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-26440090
[Journal Article] TDP-43タンパク質凝集形成過程におけるシャペロンRNAの役割2023
- Author(s)
  北村朗，藤本愛
- Journal Title
  
  Bio Clinica
  
  Volume: 38 Pages: 56-59
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Journal Article] Intracellular Conformation of Amyotrophic Lateral Sclerosis-Causative TDP-432023
- Author(s)
  Kitamura Akira、Yuno Sachiko、Kawamura Rintaro、Kinjo Masataka
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 6 Pages: 5513-5513
- DOI
  10.3390/ijms24065513
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19886, KAKENHI-PUBLICLY-22H04826, KAKENHI-PROJECT-23K23842
[Journal Article] Trans-cis isomerization kinetics of cyanine dyes reports on the folding states of exogeneous RNA G-quadruplexes in live cells2023
- Author(s)
  Kitamura Akira、Tornmalm Johan、Demirbay Baris、Piguet Joachim、Kinjo Masataka、Widengren Jerker
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 51 Issue: 5 Pages: e27-e27
- DOI
  10.1093/nar/gkac1255
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19886, KAKENHI-PUBLICLY-22H04826, KAKENHI-PROJECT-23K23842
[Journal Article] Short repeat RNA reduces cytotoxicity by preventing the aggregation of TDP-43 and its 25 kDa carboxy-terminal fragment2022
- Author(s)
  Fujimoto Ai、Kinjo Masataka、Kitamura Akira
- Journal Title
  
  bioRxiv (preprint)
  
  Volume: -
- DOI
  10.1101/2022.07.03.498631
- Open Access
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Journal Article] Physico- and chemical biology using nanomanipulation and micromanipulation technologies2022
- Author(s)
  Akira Kitamura, Ryo Iizuka
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 19 Issue: 0 Pages: n/a
- DOI
  10.2142/biophysico.bppb-v19.0044
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05310, KAKENHI-PUBLICLY-22H04826
[Journal Article] Increased intracellular crowding during hyperosmotic stress2022
- Author(s)
  Kitamura Akira、Oasa Sho、Kawaguchi Haruka、Osaka Misato、Vukojevic Vladana、Kinjo Masataka
- Journal Title
  
  bioRxiv (preprint)
  
  Volume: -
- DOI
  10.1101/2022.12.30.522363
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Journal Article] Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity2022
- Author(s)
  Kitamura Akira、Fujimoto Ai、Kawashima Rei、Lyu Yidan、Moriya Kanami、Kurata Ayumi、Takahashi Kazuho、Brielmann Renee、Bott Laura C.、Morimoto Richard I.、Kinjo Masataka
- Journal Title
  
  bioRxiv (preprint)
  
  Volume: -
- DOI
  10.1101/2022.05.22.493003
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Journal Article] ALSとFTD関連TDP-43タンパク質凝集形成過程におけるRNAの役割2022
- Author(s)
  北村朗，藤本愛
- Journal Title
  
  月刊「細胞」
  
  Volume: 54 Pages: 474-477
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Journal Article] Detection of protein aggregation using fluorescence correlation spectroscopy.2021
- Author(s)
  Kitamura Akira, Fujimoto Ai, Kinjo Masakata
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 170 Issue: 170
- DOI
  10.3791/62576
- NAID
  120007097384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06201, KAKENHI-ORGANIZER-19H05794
[Journal Article] Analysis of the triplet-state kinetics of a photosensitizer for photoimmunotherapy by fluorescence correlation spectroscopy2021
- Author(s)
  Takakura Hideo、Goto Yuto、Kitamura Akira、Yoshihara Toshitada、Tobita Seiji、Kinjo Masataka、Ogawa Mikako
- Journal Title
  
  Journal of Photochemistry and Photobiology A: Chemistry
  
  Volume: 408 Pages: 113094-113094
- DOI
  10.1016/j.jphotochem.2020.113094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03509, KAKENHI-PROJECT-18K06201, KAKENHI-PROJECT-19K22947
[Journal Article] Molecular basis of functional exchangeability between ezrin and other actin-membrane associated proteins during cytokinesis2021
- Author(s)
  Yang Guang、Hiruma Shota、Kitamura Akira、Kinjo Masataka、Mishra Mithilesh、Uehara Ryota
- Journal Title
  
  Experimental Cell Research
  
  Volume: 403 Issue: 2 Pages: 112600-112600
- DOI
  10.1016/j.yexcr.2021.112600
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06201, KAKENHI-PUBLICLY-20H05522, KAKENHI-PROJECT-19H03219, KAKENHI-PROJECT-19KK0181, KAKENHI-ORGANIZER-19H05794
[Journal Article] ALSにおけるTDP-43タンパク質凝集体形成と遺伝子治療2021
- Author(s)
  北村朗
- Journal Title
  
  Bio Clinica
  
  Volume: 36 Pages: 453-456
- Data Source
  KAKENHI-PROJECT-18K06201
[Journal Article] Spatial Image Correlation Spectroscopy (ICS): A Technique for Average Size Determination of Subcellular Accumulated Structures from Fluorescence Microscopic Images2020
- Author(s)
  Kitamura Akira、Kinjo Masakata
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 10 Issue: 10
- DOI
  10.21769/bioprotoc.3624
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04686, KAKENHI-PUBLICLY-20H05522, KAKENHI-PROJECT-18K06201
[Journal Article] ALSにおけるタンパク質凝集体と遺伝子治療2020
- Author(s)
  北村朗
- Journal Title
  
  メディカル・サイエンス・ダイジェスト (MSD)
  
  Volume: 46 Pages: 763-765
- Data Source
  KAKENHI-PROJECT-18K06201
[Journal Article] Session 2SHP report - decoding intracellular architecture using visualizing device development and mathematical modeling2020
- Author(s)
  Kitamura A., Kabayama K.
- Journal Title
  
  Biophysical Reviews
  
  Volume: x Issue: 2 Pages: 1-2
- DOI
  10.1007/s12551-020-00641-4
- NAID
  120007000859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05356, KAKENHI-PROJECT-18K06201, KAKENHI-PROJECT-16KK0156
[Journal Article] Membrane Surface Modulates Slow Diffusion in Small Crowded Droplets2020
- Author(s)
  Harusawa Kanae、Watanabe Chiho、Kobori Yuta、Tomita Kazuho、Kitamura Akira、Kinjo Masataka、Yanagisawa Miho
- Journal Title
  
  Langmuir
  
  Volume: 37 Issue: 1 Pages: 437-444
- DOI
  10.1021/acs.langmuir.0c03086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04686, KAKENHI-PUBLICLY-20H05522, KAKENHI-PROJECT-18K06201, KAKENHI-PROJECT-18H01187
[Journal Article] The AAA+ ATPase/ubiquitin ligase mysterin stabilizes cytoplasmic lipid droplets2019
- Author(s)
  Munechika Sugihara, Daisuke Morito, Shiori Ainuki, Yoshinobu Hirano, Kazutoyo Ogino, Akira Kitamura, Hiromi Hirata, Kazuhiro Nagata
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 218 Issue: 3 Pages: 949-960
- DOI
  10.1083/jcb.201712120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06201, KAKENHI-PUBLICLY-17H05578, KAKENHI-PROJECT-18H04002, KAKENHI-PROJECT-16H04657
[Journal Article] Characterization of Intracellular Crowding Environments with Topology-Based DNA Quadruplex Sensors2019
- Author(s)
  Takahashi Shuntaro、Yamamoto Johtaro、Kitamura Akira、Kinjo Masataka、Sugimoto Naoki
- Journal Title
  
  Analytical Chemistry
  
  Volume: 91 Issue: 4 Pages: 2586-2590
- DOI
  10.1021/acs.analchem.8b04177
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01968, KAKENHI-PROJECT-18K06201, KAKENHI-PROJECT-18K19152, KAKENHI-PLANNED-17H06351, KAKENHI-PROJECT-16H02283, KAKENHI-PROJECT-16KK0156
[Journal Article] Encapsulation of biomacromolecules by soaking and co-crystallization into porous protein crystals of hemocyanin2019
- Author(s)
  Tsubasa Hashimoto, Yuxin Ye, Asuka Matsuno, Yuki Ohnishi, Akira Kitamura, Masataka Kinjo, Satoshi Abe, Takafumi Uenod, Min Yao, Tomohisa Ogawa, Takashi Matsuia, Yoshikazu Tanaka
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 509 Issue: 2 Pages: 577-584
- DOI
  10.1016/j.bbrc.2018.12.096
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06201, KAKENHI-PROJECT-18K19143, KAKENHI-PROJECT-17KK0141, KAKENHI-PLANNED-18H05421, KAKENHI-PROJECT-16H04177, KAKENHI-PROJECT-16K18501, KAKENHI-PROJECT-15KK0248, KAKENHI-PUBLICLY-16H00748
[Journal Article] 蛍光相関分光の発展と応用，その最新動向2019
- Author(s)
  山本条太郎，北村朗，金城政孝
- Journal Title
  
  生物物理
  
  Volume: 印刷中
- NAID
  130007653211
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06201
[Journal Article] TDP-43 depletion: mechanism of neuronal cell death in ALS2018
- Author(s)
  Akira Kitamura
- Journal Title
  
  Future Neurology
  
  Volume: 13 Issue: 3 Pages: 143-149
- DOI
  10.2217/fnl-2018-0010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06201
[Journal Article] Molecular chaperone HSP70 prevents formation of inclusion bodies of the 25-kDa C-terminal fragment of TDP-43 by preventing aggregate accumulation2018
- Author(s)
  Akira Kitamura, Nodoka Iwasaki, Masataka Kinjo
- Journal Title
  
  Cell Stress and Chaperones
  
  Volume: 23 Issue: 6 Pages: 1177-1183
- DOI
  10.1007/s12192-018-0930-1
- NAID
  120006734164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06201
[Journal Article] Analysis of the substrate recognition state of TDP-43 to single-stranded DNA using fluorescence correlation spectroscopy2018
- Author(s)
  Akira Kitamura, Ai Shibasaki, Kayo Takeda, Ryoji Suno, Masataka Kinjo
- Journal Title
  
  Biochem. Biophys. Reports
  
  Volume: 14 Pages: 58-63
- DOI
  10.1016/j.bbrep.2018.03.009
- NAID
  120006491827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06201
[Journal Article] Determination of cytoplasmic optineurin foci sizes using image correlation spectroscopy2018
- Author(s)
  Akira Kitamura, Hiroki Shimizu, Masataka Kinjo
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 164 Issue: 3 Pages: 223-229
- DOI
  10.1093/jb/mvy044
- NAID
  120006716318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06201
[Journal Article] The cytoplasmic region of the amyloid β‐protein precursor (APP) is necessary and sufficient for the enhanced fast velocity of APP transport by kinesin‐12018
- Author(s)
  Maoko Tsukamoto Kyoko Chiba Yuriko Sobu Yuzuha Shiraki Yuka Okumura Saori Hata Akira Kitamura Tadashi Nakaya Seiichi Uchida Masataka Kinjo Hidenori Taru Toshiharu Suzuki
- Journal Title
  
  FEBS Letters
  
  Volume: 592 Issue: 16 Pages: 2716-2724
- DOI
  10.1002/1873-3468.13204
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06201, KAKENHI-PROJECT-18K07384, KAKENHI-PUBLICLY-18H04851, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-18H02566
[Journal Article] Different aggregation states of a nuclear localization signal-tagged 25-kDa C-terminal fragment of TAR RNA/ 1 DNA-binding protein 43 kDa2017
- Author(s)
  Akira Kitamura, Sachiko Yuno, Hideki Muto, Masataka Kinjo
- Journal Title
  
  Genes to Cells
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26440090
[Journal Article] In vivo fluorescence correlation spectroscopy analyses of FMBP-1, a silkworm transcription factor2016
- Author(s)
  Motosuke Tsutsumi, Hideki Muto, Shohei Myoba, Mai Kimoto, Akira Kitamura, Masakatsu Kamiya, Takashi Kikukawa, Shigeharu Takiya, Makoto Demura, Keiichi Kawano, Masataka Kinjo, Tomoyasu Aizawa
- Journal Title
  
  FEBS openbio
  
  Volume: 6 Issue: 2 Pages: 106-125
- DOI
  10.1002/2211-5463.12026
- NAID
  120005756103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440090, KAKENHI-PROJECT-14J02640, KAKENHI-PROJECT-15K01805
[Journal Article] Development of new fusion proteins for visualizing amyloid-beta oligomers in vivo.2016
- Author(s)
  Tomoyo Ochiishi, Motomichi Doi, Kazuhiko Yamasaki, Keiko Hirose, Akira Kitamura, Takao Urabe, Nobutaka Hattori, Masataka Kinjo, Tatsuhiko Ebihara & Hideki Shimura
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 22712-22712
- DOI
  10.1038/srep22712
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440090, KAKENHI-PROJECT-15K14499, KAKENHI-PROJECT-26640023, KAKENHI-PROJECT-15K14338
[Journal Article] Dependence of fluorescent protein brightness on protein concentration in solution and enhancement of it.2016
- Author(s)
  Takamitsu J. Morikawa, Hideaki Fujita, Akira Kitamura, Takashi Horio, Johtaro Yamamoto, Masataka Kinjo, Akira Sasaki, Hiroaki Machiyama, Keiko Yoshizawa, Taro Ichimura, Katsumi Imada, Takeharu Nagai & Tomonobu M. Watanabe
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 22342-22342
- DOI
  10.1038/srep22342
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440090, KAKENHI-PLANNED-23115002, KAKENHI-PLANNED-23115003, KAKENHI-PLANNED-23115008, KAKENHI-PROJECT-26650036, KAKENHI-PROJECT-26840057, KAKENHI-PROJECT-26291028
[Journal Article] Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity.2016
- Author(s)
  Akira Kitamura, Yusaku Nakayama, Ai Shibasaki, Ayami Taki, Sachiko Yuno, Kayo Takeda, Masao Yahara, Naoki Tanabe & Masataka Kinjo
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 19230-19230
- DOI
  10.1038/srep19230
- NAID
  120005749614
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440090
[Journal Article] Efficient and dynamic nuclear localization of green fluorescent protein via RNA binding.2015
- Author(s)
  Akira Kitamura, Yusaku Nakayama, Masataka Kinjo
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 463 Issue: 3 Pages: 401-406
- DOI
  10.1016/j.bbrc.2015.05.084
- NAID
  120005820695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26440090
[Journal Article] Conformational analysis of misfolded protein aggregation by FRET and live-cell imaging techniques.2015
- Author(s)
  Akira Kitamura, Kazuhiro Nagata, Masataka Kinjo
- Journal Title
  
  International Journal of Molecular Science
  
  Volume: 16 Issue: 3 Pages: 6076-6092
- DOI
  10.3390/ijms16036076
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440090, KAKENHI-PROJECT-24227009
[Journal Article] Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ AT Pase, which dynamically changes its oligomeric state2014
- Author(s)
  Daisuke Morito, Kouki Nishikawa, Jun Houseki, Akira Kitamura, Yuri Kotani, Kazumi Kiso, Masataka Kinjo, Yoshimori Fujiyoshi & Kazuhiro Nagata
- Journal Title
  
  SCIENTIFIC REPORTS
  
  Volume: Vol. 4 Issue: 1 Pages: 4442-4442
- DOI
  10.1038/srep04442
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J07825, KAKENHI-PROJECT-23770215, KAKENHI-PROJECT-24227009, KAKENHI-PUBLICLY-25122717, KAKENHI-PROJECT-25840024
[Journal Article] Dysregulation of the Proteasome Enhances the Toxicity of ALS-linked Mutant SOD12014
- Author(s)
  Kitamura, A., Inada, N., Kubota, H., Matsumoto, G., Kinjo, M., Morimoto, R.I., Nagata, K
- Journal Title
  
  Genes to Cells
  
  Volume: 3 Issue: 3 Pages: 209-224
- DOI
  10.1111/gtc.12125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23500434, KAKENHI-PROJECT-23770215, KAKENHI-PUBLICLY-24111554, KAKENHI-PROJECT-24227009
[Journal Article] 蛍光相関分光法とFRET を用いた細胞内タンパク質品質管理機構の解析2014
- Author(s)
  北村朗
- Journal Title
  
  バイオイメージング
  
  Volume: 23 Pages: 12-17
- NAID
  120005572424
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440090
[Journal Article] Prefoldin prevents aggregation of alpha-synuclein.2014
- Author(s)
  Takano M., Tashiro E., Kitamura A., Maita H., Iguchi-Ariga M.M.S., Kinjo M., Ariga H.
- Journal Title
  
  Brain Research
  
  Volume: 1542 Pages: 186-194
- DOI
  10.1016/j.brainres.2013.10.034
- NAID
  120005397867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770215
[Journal Article] The interaction of Hsp104 with yeast prion Sup35 as analyzed by fluorescence cross-correlation spectroscopy.oligomeric state.2013
- Author(s)
  Ohta S., Kawai-Noma S., Kitamura A., Pack C.G., Kinjo M., Taguchi H.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 442 Issue: 1-2 Pages: 28-32
- DOI
  10.1016/j.bbrc.2013.10.147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770215, KAKENHI-PUBLICLY-24113705, KAKENHI-PROJECT-24657070
[Journal Article] Nonmuscle myosin II folds into a 10S form via two portions of tail for dynamic subcellular loacalization.2013
- Author(s)
  Kiboku T.
- Journal Title
  
  Genes to Cells.
  
  Volume: 18(2) Issue: 2 Pages: 90-109
- DOI
  10.1111/gtc.12021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21221006, KAKENHI-PROJECT-22570129, KAKENHI-PROJECT-23590295, KAKENHI-PROJECT-23770169, KAKENHI-PROJECT-23770215, KAKENHI-PUBLICLY-25118502, KAKENHI-PROJECT-25650001, KAKENHI-PUBLICLY-23114701
[Journal Article] Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation.2013
- Author(s)
  Tashiro E, Zako T, Muto H, Itoo Y, Sorgjerd K, Terada N, Abe A, Miyazawa M, Kitamura A, Kitaura H, Kubota H, Maeda M, Momoi T, Iguchi-Ariga SM, Kinjo M, Ariga H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Issue: 27 Pages: 19958-19972
- DOI
  10.1074/jbc.m113.477984
- NAID
  120005323603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-23770215, KAKENHI-PROJECT-24570143, KAKENHI-PROJECT-24651223
[Journal Article] Atg9 vesicles are an important membrane source during early steps of autophagosome formation.2012
- Author(s)
  Yamamoto H.
- Journal Title
  
  J. Cell Biol.
  
  Volume: 198(2) Issue: 2 Pages: 219-233
- DOI
  10.1083/jcb.201202061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21221006, KAKENHI-PROJECT-23370072, KAKENHI-PROJECT-23770215, KAKENHI-PROJECT-24770182
[Journal Article] Direct association of unfolded proteins with mammalian ER stress sensor, IRE1 beta.2012
- Author(s)
  Oikawa D.
- Journal Title
  
  PLoS One.
  
  Volume: 7(12) Issue: 12 Pages: e51290-e51290
- DOI
  10.1371/journal.pone.0051290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21221006, KAKENHI-PROJECT-23770215, KAKENHI-PROJECT-24390049, KAKENHI-PUBLICLY-24113702
[Journal Article] Analyzing the aggregation of polyglutamine-expansion proteins and its modulation by molecular chaperones2011
- Author(s)
  Kubota H, Kitamura A, Nagata K.
- Journal Title
  
  Methods
  
  Volume: 53(3) Issue: 3 Pages: 267-274
- DOI
  10.1016/j.ymeth.2010.12.035
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058001
[Journal Article] Analyzing the aggregation of polyglutamine-expansion proteins and its modulation by molecular chaperones.2011
- Author(s)
  Kubota H, Kitamura A, Nagata K.
- Journal Title
  
  Methods
  
  Volume: 53 Pages: 267-274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770215
[Journal Article] Amyloid oligomers : dynamics and toxicity in the cytosol and nucleus.2010
- Author(s)
  Akira Kitamura
- Journal Title
  
  FEBS Journal 277
  
  Pages: 1369-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-08J04474
[Journal Article] MKKS Is a Centrosome-shuttling Protein Degraded by Disease-causing Mutations via CHIP-mediated Ubiquitination.2008
- Author(s)
  Hirayama S., Vamazaki Y., Kitamura A., Oda Y., Morito D., Okawa K., Kimura H., Cyr D. M., Kubota H., Nagata K.
- Journal Title
  
  Molecular Biology of the Cell 19
  
  Pages: 889-911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-06J03037
[Journal Article] 細胞質シャペロニンCCTが異常タンパク質凝集の初期課程を抑制して細胞毒性を防止する.2007
- Author(s)
  久保田広志, 北村朗, 永田和宏
- Journal Title
  
  細胞工学 2月号
  
  Pages: 188-189
- Data Source
  KAKENHI-PROJECT-06J03037
[Journal Article] Cytosolic chaperonin prevents polyglutamine toxicity with altering aggregation state.2006
- Author(s)
  Kitamura A., et al.
- Journal Title
  
  Nature Cell Biology 8
  
  Pages: 1163-1170
- NAID
  120005549596
- Data Source
  KAKENHI-PROJECT-06J03037
[Journal Article] ポリグルタミンタンパク質凝集を抑え神経細胞を守るシャペロニンCCT.2006
- Author(s)
  北村朗, 久保田広志, 永田和宏
- Journal Title
  
  Bionics 12月号
  
  Pages: 80-81
- Data Source
  KAKENHI-PROJECT-06J03037
[Patent] ＴＤＰ４３、ＴＤＰ３５、またはＴＤＰ２５の凝集を特徴とする神経変性疾患の治療剤、進行抑制剤、および予防剤2022
- Inventor(s)
  北村朗，藤本愛
- Industrial Property Rights Holder
  北村朗，藤本愛
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Patent] ヘモシアニン会合体を用いた包摂体の製造方法2016
- Inventor(s)
  田中良和、松野明日香、北村朗、金城政孝、姚閔、上野隆史、安部聡
- Industrial Property Rights Holder
  田中良和、松野明日香、北村朗、金城政孝、姚閔、上野隆史、安部聡
- Industrial Property Rights Type
  特許
- Filing Date
  2016-06-01
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] 筋萎縮性側索硬化症の原因タンパク質 TDP43 凝集体を防ぐシャペロン RNA2023
- Author(s)
  藤本愛，金城政孝，北村朗
- Organizer
  2022年度生物物理学会北海道支部・東北支部合同例会
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] TDP43の凝集体を抑制できるRNA2023
- Author(s)
  藤本愛，金城政孝，北村朗
- Organizer
  第14回光塾
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] 光誘起多量体形成システムを用いた天然変性タンパク質の凝集体形成過程解明2023
- Author(s)
  濱田悠太, 金城政孝, 北村朗
- Organizer
  第14回光塾
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] 筋萎縮性側索硬化症(ALS)の原因タンパク質TDP43に対するシャペロンRNAの基質認識機構と細胞毒性低減効果2023
- Author(s)
  藤本愛，金城政孝，北村朗
- Organizer
  令和４年度北大細胞生物研究集会
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] Intracellular crowding during hyperosmotic stress2023
- Author(s)
  Akira Kitamura, Sho Oasa, Vladana Vukojevic, Masataka Kinjo
- Organizer
  第14回光塾
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] Intracellular structure and function of chaperone RNA2022
- Author(s)
  Akira Kitamura
- Organizer
  International Workshop on Fluorescence Methods and Applications 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] 回転拡散と並進拡散の解析による凝集性タンパク質の検出2022
- Author(s)
  Riku Ando　, Johtaro Yamamoto, Akira Kitamura , Nori Nakai　, Sumio Terada　, Masataka Kinjo
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-23K23842
[Presentation] Elucidation of the phase separation process of intrinsically disordered protein using an optogenetic oligomerization tag2022
- Author(s)
  Yuta Hamada, Masataka Kinjo, Akira Kitamura
- Organizer
  8th International Life Science Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] GGGGCC-RNA chaperones to inhibit aggregation of TDP43 and its carboxy fragments2022
- Author(s)
  藤本愛，金城政孝，北村朗
- Organizer
  第60回　日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] GGGGCC-RNA は、TDP43 およびそのカルボキシ断片の凝集を抑制する2022
- Author(s)
  Ai Fujimoto , Masataka Kinjo , Akira Kitamura
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K19886
[Presentation] Basics and applications of chromophore-assisted light inactivation (CALI)2022
- Author(s)
  北村朗
- Organizer
  第60回　日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] (1SAA-8) GGGGCC-RNA は、TDP43 およびそのカルボキシ断片の凝集を抑制する2022
- Author(s)
  Ai Fujimoto , Masataka Kinjo , Akira Kitamura
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-23K23842
[Presentation] Size determination of cytoplasmic condensates of optineurin using spatial image correlation spectroscopy (SICS)2022
- Author(s)
  Yuta Hamada　, Masataka Kinjo　, Akira Kitamura
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-23K23842
[Presentation] 筋萎縮性側索硬化症(ALS)の原因タンパク質TDP43の凝集を抑制するシャペロンRNAの基質認識機構と細胞毒性低減効果2022
- Author(s)
  藤本愛，金城政孝，北村朗
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] 回転拡散と並進拡散の解析による凝集性タンパク質の検出2022
- Author(s)
  Riku Ando　, Johtaro Yamamoto, Akira Kitamura , Nori Nakai　, Sumio Terada　, Masataka Kinjo
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K19886
[Presentation] Size determination of cytoplasmic condensates of optineurin using spatial image correlation spectroscopy (SICS)2022
- Author(s)
  濱田悠太, 金城政孝, 北村朗
- Organizer
  第60回　日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] Size determination of cytoplasmic condensates of optineurin using spatial image correlation spectroscopy (SICS)2022
- Author(s)
  Yuta Hamada　, Masataka Kinjo　, Akira Kitamura
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K19886
[Presentation] The E50K mutation of optineurin increases the oligomer size（Optineurinの緑内障変異はオリゴマー粒形を増大させる）2022
- Author(s)
  河村綸太郎，植月聡也，丹澤豪人，加藤貴之，金城政孝，北村朗
- Organizer
  第60回　日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] RNA構造変化を蛍光ブリンキングで検出する2022
- Author(s)
  北村朗
- Organizer
  第45回　日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04826
[Presentation] Interaction analysis of aggregate-prone protein TDP25 and RNA in amyotrophic lateral sclerosis (ALS)2021
- Author(s)
  藤本愛, 金城政孝, 北村朗
- Organizer
  北大細胞生物研究集会
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] Lifespan and motility analysis of C. elegans expressing C-terminal fragments of ALS-causative TDP-432021
- Author(s)
  Yidan Lyu, Rei Kawashima, Renee; Brielman, Richard I. Morimoto, Masataka Kinjo, Akira Kitamura
- Organizer
  RIKEN BDP Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] 蛍光相関分光法による蛍光分子光物理反応速度定数の同定 -新規免疫治療薬剤の定量的開発指針の確立に向けて-2020
- Author(s)
  北村朗，高倉栄男，後藤悠人，金城政孝，小川美香子
- Organizer
  2020年度・光イメージン若手の会「光塾」
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] Aggregation process of carboxyl terminal fragments of TDP-43 protein2020
- Author(s)
  Akira Kitamura, Masataka Kinjo
- Organizer
  Cold Spring Harbor Laboratory 2020 Meeting "Protein homeostasis in Health & Disease"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] Elucidation for stress granule function using chromophore-assisted light inactivation (CALI)2019
- Author(s)
  Akira Kitamura, Haruka Kawaguchi, Tsumugi Kurosaki, Masataka Kinjo
- Organizer
  第42回　日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] Aggregation process of carboxyl terminal fragments of TDP-432019
- Author(s)
  Akira Kitamura, Kanami Moriya, Kazuho Takahashi, Rei Kawashima, Renee Brielman, Richard I. Morimoto, Masataka Kinjo
- Organizer
  Asian Pacific Prion Symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] Elucidation for stress granule function using chromophore-assisted light inactivation (CALI)2019
- Author(s)
  Akira Kitamura, Haruka Kawaguchi, Tsumugi Kurosaki, Masataka Kinjo
- Organizer
  第42回　日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KK0156
[Presentation] 蛍光相関分光法とその応用法を用いたALS関連細胞内凝集体形成機構の解析2019
- Author(s)
  北村朗
- Organizer
  サントリー生命科学財団　生物有機科学研究所　生有研シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16KK0156
[Presentation] 蛍光ゆらぎを利用した光化学反応速度定数の算出とRNA構造変化の解析2019
- Author(s)
  北村朗, Johan Tormmalm，Jerker Widengren, 金城政孝
- Organizer
  第10回・光塾
- Data Source
  KAKENHI-PROJECT-16KK0156
[Presentation] Aggregation process of carboxyl terminal fragments of TDP-432019
- Author(s)
  Akira Kitamura, Kanami Moriya, Kazuho Takahashi, Rei Kawashima, Renee Brielman, Richard I. Morimoto, Masataka Kinjo
- Organizer
  Asian Pacific Prion Symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KK0156
[Presentation] Reading out G-quadruplex RNA structure using transient state (TRAST) of photochemical reaction of fluorophores2019
- Author(s)
  北村朗
- Organizer
  第57回　日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] 蛍光ゆらぎを利用した光化学反応速度定数の算出とRNA構造変化の解析2019
- Author(s)
  北村朗, Johan Tormmalm，Jerker Widengren, 金城政孝
- Organizer
  第10回・光塾
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] Reading out G-quadruplex RNA structure using transient state (TRAST) of photochemical reaction of fluorophores2019
- Author(s)
  北村朗
- Organizer
  第57回　日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16KK0156
[Presentation] 蛍光相関分光法とその応用法を用いたALS関連細胞内凝集体形成機構の解析2019
- Author(s)
  北村朗
- Organizer
  サントリー生命科学財団　生物有機科学研究所　生有研シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] Aggregation process of carboxyl terminal fragments of TDP-432019
- Author(s)
  Akira Kitamura, Kanami Moriya, Kazuho Takahashi, Rei Kawashima, Renee Brielman, Richard I. Morimoto, Masataka Kinjo
- Organizer
  QBP/OCS seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] Aggregation process of carboxyl terminal fragments of TDP-432019
- Author(s)
  Akira Kitamura, Kanami Moriya, Kazuho Takahashi, Rei Kawashima, Renee Brielman, Richard I. Morimoto, Masataka Kinjo
- Organizer
  QBP/OCS seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KK0156
[Presentation] Transient state (TRAST) monitoringを用いた生細胞内RNAフォールドの解析2019
- Author(s)
  北村朗
- Organizer
  定量生物の会　北海道キャラバン2019
- Invited
- Data Source
  KAKENHI-PROJECT-16KK0156
[Presentation] Transient state (TRAST) monitoringを用いた生細胞内RNAフォールドの解析2019
- Author(s)
  北村朗
- Organizer
  定量生物の会　北海道キャラバン2019
- Invited
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] 蛍光ゆらぎを利用した生体分子構造変化の解析2018
- Author(s)
  北村朗
- Organizer
  第55回　日本生化学会北海道支部例会，日本生物物理学会北海道支部合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] RNA prevents ALS-linked protein aggregation2018
- Author(s)
  Akira Kitamura
- Organizer
  QBP/OCS seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06201
[Presentation] Wide-field光学系FRAPを用いた生細胞内拡散係数の測定検討2016
- Author(s)
  北村朗，金城政孝
- Organizer
  第７回　光塾
- Place of Presentation
  東京工業大学（神奈川県長津田市）
- Year and Date
  2016-12-17
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] ALS関連変異型TDP-43の生細胞内構造変化と凝集性の解析2016
- Author(s)
  北村朗，油野祥子，柴崎愛，竹田佳世，顔総子，大浦真，山本条太郎，金城政孝
- Organizer
  第39回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] 蛍光イメージング手法を用いたALS関連TDP43凝集形成機構の解析2016
- Author(s)
  北村朗
- Organizer
  第７回　ALSフォーラム
- Place of Presentation
  シェラトン都ホテル東京（東京都・港区）
- Year and Date
  2016-07-30
- Invited
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] 蛍光イメージング手法を用いた ALS関連TDP43凝集形成機構の解析2016
- Author(s)
  北村朗
- Organizer
  第７回　ALSフォーラム
- Place of Presentation
  ウェスティン都ホテル東京（東京都港区）
- Year and Date
  2016-07-30
- Invited
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] FRAP/FCS を用いた分子動態解析を用いた神経変性疾患原因研究の最前線2016
- Author(s)
  北村朗
- Organizer
  第39回　日本分子生物学会年会　Leicaランチョンセミナー
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] ALS関連TDP43の構造および凝集性と神経細胞死機構の解析2016
- Author(s)
  北村朗
- Organizer
  IGM RNA Biofunctionセミナー
- Place of Presentation
  北海道大学遺伝子病制御研究所（北海道・札幌市）
- Year and Date
  2016-02-29
- Invited
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] Optineurinのオートファゴソーム局在化機構の解明2016
- Author(s)
  田辺尚貴，北村朗，金城政孝
- Organizer
  第１回　北大・部局横断シンポジウム
- Place of Presentation
  北海道大学医学部（北海道・札幌市）
- Year and Date
  2016-03-07
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] ALS関連TDP43のRNA/DNA結合様式の解析2016
- Author(s)
  竹田佳世，北村朗，柴崎愛，金城政孝
- Organizer
  第１回　北大・部局横断シンポジウム
- Place of Presentation
  北海道大学医学部（北海道・札幌市）
- Year and Date
  2016-03-07
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] ALS関連変異型TDP-43の生細胞内構造変化と凝集性の解析2016
- Author(s)
  北村朗，油野祥子，柴崎愛，竹田佳世，顔総子，大浦真，山本条太郎，金城政孝
- Organizer
  RNAフロンティアミーティング2016
- Place of Presentation
  いこいの湯いろは（北海道ニセコ町）
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] 蛍光イメージング法による神経変性疾患関連ミスフォールドタンパク質の凝集形成機構解析2016
- Author(s)
  北村朗
- Organizer
  生化学若手の会・生物物理若手の会合同企画「蛍光イメージングセミナー～基礎から応用まで～」
- Place of Presentation
  北海道大学（北海道札幌市）
- Year and Date
  2016-07-01
- Invited
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] FCS and FCCS in living cells2016
- Author(s)
  Akira Kitamura & Masataka Kinjo
- Organizer
  Course Functional Fluorescence Microscopy Imaging (fFMI) in Biomedical Research
- Place of Presentation
  カロリンスカ研究所（ストックホルム・スウェーデン）
- Year and Date
  2016-11-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] Basics and application of fluorescence correlation spectroscopy2016
- Author(s)
  北村朗
- Organizer
  3rd AIST International Imaging Workshop
- Place of Presentation
  独立行政法人産業技術総合研究所（茨城県・つくば市）
- Year and Date
  2016-01-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] 蛍光イメージング手法を用いた神経変性疾患関連タンパク質凝集形成機構の解析2016
- Author(s)
  北村朗
- Organizer
  生物物理・生化学若手の会北海道支部合同セミナー
- Place of Presentation
  北海道大学理学部（北海道・札幌市）
- Year and Date
  2016-07-01
- Invited
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] U6 snRNA強制発現はTDP43機能喪失に伴う細胞死を抑制する2016
- Author(s)
  矢原真郎，北村朗，金城政孝
- Organizer
  第１回　北大・部局横断シンポジウム
- Place of Presentation
  北海道大学医学部（北海道・札幌市）
- Year and Date
  2016-03-07
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] 大腸菌組換えTDP43のRNA/DNA結合様式の解析2015
- Author(s)
  竹田佳世，北村朗，柴崎愛，金城政孝
- Organizer
  第１回　北大イメージング研究会
- Place of Presentation
  北海道大学医学部（北海道・札幌市）
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] ALS関連TDP43 C末端断片のRNA結合と核局在は凝集性と共に神経細胞毒性を低減する2015
- Author(s)
  北村朗，中山祐作，柴崎愛，滝彩実，油野祥子，金城政孝
- Organizer
  第七回・光塾
- Place of Presentation
  広島大学（広島県・東広島市）
- Year and Date
  2015-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] イメージング手法を用いた神経変性疾患関連タンパク質封入体の形成機構解析2015
- Author(s)
  北村朗
- Organizer
  第４回・蛍光イメージング・ミニシンポジウム
- Place of Presentation
  北海道大学電子科学研究所（北海道・札幌市）
- Year and Date
  2015-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] 蛍光相関分光法を用いた大腸菌組み換えTDP43の一本鎖DNA結合解離定数の測定2015
- Author(s)
  竹田佳世，柴崎愛，北村朗，金城政孝
- Organizer
  第17回・日本RNA学会年会
- Place of Presentation
  札幌パークホテル（北海道・札幌市）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] RNAと核小体局在はALS関連TDP43のカルボキシル末端断片に存在するプリオン様ドメインの構造変化を妨げることで凝集形成と毒性を低減させる2015
- Author(s)
  北村朗，中山祐作，柴崎愛，滝彩実，油野祥子，金城政孝
- Organizer
  BMB2015
- Place of Presentation
  神戸国際展示場（兵庫県・神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] TDP43機能喪失に伴うスプライシング関連低分子RNA恒常性破綻を介した神経細胞死メカニズムの解明2015
- Author(s)
  矢原真郎，北村朗，金城政孝
- Organizer
  第１回　北大イメージング研究会
- Place of Presentation
  北海道大学医学部（北海道・札幌市）
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] ALS関連変異型TDP43に見られる核－細胞質輸送と構造変調2015
- Author(s)
  北村朗，柴崎愛，油野祥子，中山祐作，金城政孝
- Organizer
  第17回・日本RNA学会年会
- Place of Presentation
  札幌パークホテル（北海道・札幌市）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] 生細胞蛍光イメージング法を用いた細胞生物学研究2014
- Author(s)
  北村朗
- Organizer
  第81回・日本細菌学会・北海道支部総会
- Place of Presentation
  札幌医科大学（北海道札幌市）
- Year and Date
  2014-08-30
- Invited
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] Actin and myosin participate in the quality control of SOD1 aggregates2013
- Author(s)
  Taku Tamura, Akihiko Yatabe, Koji Ichinohe, Yuko Shimizu, Akira Kitamura, Masataka Kinjo, Hiroshi Kubota
- Organizer
  International Mini-symposium: Protein Folding and Disease
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] アクチン・ミオシン系は筋萎縮性側索硬化症原因タンパク質SOD1変異体の凝集制御および分解に関与する2013
- Author(s)
  田村拓, 矢田部暁彦, 一戸康治, 清水佑子, 北村朗, 金城政孝, 久保田広志
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] Actin and myosin participate in the quality control of SOD1 aggregates2013
- Author(s)
  Taku Tamura, Akihiko Yatabe, Koji Ichinohe, Yuko Shimizu, Akira Kitamura, Masataka Kinjo, Hiroshi Kubota
- Organizer
  International Mini-symposium Protein Folding and Disease
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] ALS関連TDP43タンパク質のカルボキシル末端断片の凝集体形成と毒性はRNAによって防御されている2012
- Author(s)
  北村　朗
- Organizer
  第5回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Place of Presentation
  京都大学原子炉実験所（大阪府泉南郡）
- Invited
- Data Source
  KAKENHI-PROJECT-21221006
[Presentation] 筋萎縮性側索硬化症原因タンパク質SOD1変異体の凝集制御および分解おけるアクチンフィラメントの役割2012
- Author(s)
  田村拓, 矢田部暁彦, 一戸康児, 清水佑子, 北村朗, 金城政孝, 久保田広志
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] RNA inhibits the toxicity of carboxyl-terminal fragments of ALS-causative TDP43 protein2011
- Author(s)
  Akira Kitamura, Yusaku Nakayama, Masataka Kinjo
- Organizer
  Cold Spring Harbor Asia, "Protein Homeostasis in Health & Disease"
- Place of Presentation
  Cold Spring Harbor Asia （中国）
- Data Source
  KAKENHI-PROJECT-23770215
[Presentation] Characterization of cytoplasmic and nuclear inclusion of ALS-causative TDP43 protein2011
- Author(s)
  Akira Kitamura, Yusaku Nakayama, Masataka Kinjo
- Organizer
  特定領域「タンパク質の社会」若手シンポジウム
- Place of Presentation
  アクティプラザ琵琶（滋賀県）
- Data Source
  KAKENHI-PROJECT-23770215
[Presentation] Characterization of cytoplasmic and nuclear inclusion of ALS-causative TDP43 protein2011
- Author(s)
  Akira Kitamura, Yusaku Nakayama, Masataka Kinjo
- Organizer
  第63回　日本細胞生物学会大会
- Place of Presentation
  北海道大学（札幌市）
- Data Source
  KAKENHI-PROJECT-23770215
[Presentation] シャペロニンHsp60のATP、Hsp10依存的なダブルリング化について2011
- Author(s)
  石田竜一, 久保田広志, 高橋弘樹, 岡俊, 北村朗, 金城政孝, 伊藤英晃
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] Aggregation and disaggregation of aggregate-prone proteins: Which is toxic?2011
- Author(s)
  Akira Kitamura
- Organizer
  奈良先端大シンポジウム(招待講演)
- Place of Presentation
  奈良先端大学院大学（奈良県）
- Data Source
  KAKENHI-PROJECT-23770215
[Presentation] Aggregation and disaggregation of aggregate-prone proteins : Which is toxic?2011
- Author(s)
  北村朗
- Organizer
  奈良先端未来開拓コロキウム
- Place of Presentation
  奈良先端科学技術大学院大学(生駒市)(招待講演)
- Year and Date
  2011-05-30
- Data Source
  KAKENHI-PROJECT-21221006
[Presentation] Aggregation and disaggregation of aggregate-prone proteins : Which is toxic?2011
- Author(s)
  北村朗
- Organizer
  奈良先端未来開拓コロキウム
- Place of Presentation
  奈良先端科学技術大学院大学(生駒市)(招待講演)
- Year and Date
  2011-05-30
- Data Source
  KAKENHI-PLANNED-19058001
[Presentation] 変異型SOD1タンパク質の脱凝集過程における細胞毒性2010
- Author(s)
  北村朗
- Organizer
  第2回・定量生物学の会年会
- Place of Presentation
  大阪大学・銀杏会館
- Year and Date
  2010-01-10
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] 細胞内でタンパク質凝集と脱凝集過程を捉える2009
- Author(s)
  北村朗
- Organizer
  第9回・日本蛋白質科学会年会
- Place of Presentation
  熊本全日空ホテルニュースカイ
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] 分光イメージング手法を用いて細胞内タンパク質の凝集体形成を解析する2009
- Author(s)
  北村朗
- Organizer
  第1回定量生物学の会年会
- Place of Presentation
  東京大学先端技術研究所
- Year and Date
  2009-01-12
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] Dynamics of aggregation and disaggregation of neurodegenerative disease-causative proteins.2009
- Author(s)
  Akira Kitamura
- Organizer
  International Conference "Protein Folding and neurodegenerative disease"
- Place of Presentation
  京都平安会館
- Year and Date
  2009-04-06
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] 原核生物における蛍光相関分光法測定-原核細胞内タンパク質品質管理機構の解明に向けて-2009
- Author(s)
  北村朗, 寿野良二, 秋山芳展, 吉田腎右, 金城政孝
- Organizer
  理研シンポジウム「蛍光相関分光で見る生体系の情報伝達(6)」
- Place of Presentation
  理化学研究所
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] SOD1脱凝集過程におけるタンパク質分解経路と細胞毒性の関係について2009
- Author(s)
  北村朗
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] 分光イメージング手法を用いたタンパク質品質管理機構の解析2009
- Author(s)
  北村朗
- Organizer
  第1回・光塾研究会
- Place of Presentation
  (独)情報通信研究機構神戸研究所
- Year and Date
  2009-08-15
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] 蛍光相関分光法および蛍光寿命イメージング顕微鏡を用いた細胞内タンパク質凝集体形成の解析2008
- Author(s)
  北村朗
- Organizer
  植物科学推進事業シンポジウム「視る生物学3-イメージングの挑戦-」
- Place of Presentation
  奈良先端大学院大学
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] 蛍光相関分光法および蛍光寿命イメージング顕微鏡を用いた細胞内タンパク質凝集体形成の解析2008
- Author(s)
  北村朗
- Organizer
  第20回動物細胞工学シンポジウム
- Place of Presentation
  東京工業大学
- Year and Date
  2008-08-04
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] 分光イメージング手法を用いた変異型SOD1タンパク質の凝集体形成と脱凝集機構の解析2008
- Author(s)
  北村朗
- Organizer
  文部科学省特定領域研究「タンパク質の一生」若手ワークショップ
- Place of Presentation
  東京大学検見川キャンパス
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] 分光イメージング手法を用いた変異型SOD1タンパク質の凝集体形成と脱凝集機構の解析2008
- Author(s)
  北村朗, 久保田広志, 稲田のりこ, 松本弦, 金城政孝, Richard I. Morimoto, 永田和宏
- Organizer
  文部科学省特定領域研究「タンパク質の一生」班会議
- Place of Presentation
  沖縄・残波ロイヤルホテル
- Year and Date
  2008-11-24
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] 分光イメージング手法を用いた変異型SOD1タンパク質の凝集体形成と脱凝集機構の解析2008
- Author(s)
  北村朗, 稲田のりこ, 松本弦, 金城政孝, Richard I. Morimoto, 久保田広志, 永田和宏
- Organizer
  BMB2008
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] Aggregation and disaggregation analysis of mutant SOD1 using fluorescence correlation spectroscopy and FLIM-FRET2008
- Author(s)
  北村朗, 稲田のりこ, 松本弦, 久保田広志, Richard I. Morimoto, 永田和宏, 金城政孝
- Organizer
  第46回日本生物物理学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-08J04474
[Presentation] 変異型SOD1タンパク質凝集体形成と脱凝集メカニズムの時空間的解析2007
- Author(s)
  北村朗
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-06J03037
[Presentation] 生細胞内イメージング法を用いたタンパク質凝集とシャペロン機能の時空間的機能解析2007
- Author(s)
  北村朗
- Organizer
  第七回日本蛋白質科学会年会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-06J03037
[Presentation] Fluorescence correlation spectroscopy analysis of the aggregation and disaggregation of amyotrophic lateral sclerosis-linked SOD1.2007
- Author(s)
  北村朗
- Organizer
  10th Workshop on FCS and related methods
- Place of Presentation
  札幌
- Year and Date
  2007-11-27
- Data Source
  KAKENHI-PROJECT-06J03037
[Presentation] プロテアソーム活性阻害からの回復過程における細胞毒性発現機構の解明
- Author(s)
  北村朗，永田和宏，金城政孝
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Data Source
  KAKENHI-PROJECT-23770215
[Presentation] 蛍光相関分光法を用いた精製リコンビナントTDP43タンパク質のDNA結合活性解析
- Author(s)
  柴崎愛，北村朗，寿野良二，金城政孝
- Organizer
  第37回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] ALS関連TDP43タンパク質の細胞内構造推定
- Author(s)
  北村朗，油野祥子，柴崎愛，寿野良二，金城政孝
- Organizer
  第六回　「光塾」
- Place of Presentation
  情報通信研究機構（兵庫県神戸市）
- Year and Date
  2014-09-06 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] ALS関連TDP43タンパク質のカルボキシル末端断片の細胞質における凝集体形成と毒性はRNAによって防御されている
- Author(s)
  北村朗，柴崎愛，中山祐作，金城政孝
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23770215
[Presentation] Increased toxicity and aggregate formation of carboxyl-terminal fragments of ALS-linked TDP43 protein in cytoplasm.
- Author(s)
  Kitamura A., Nakayama Y. Shibasaki A., & Kinjo M.
- Organizer
  FASEB summer research conference
- Place of Presentation
  Vermont Academy (USA)
- Data Source
  KAKENHI-PROJECT-23770215
[Presentation] ALS関連変異型TDP43に見られる異常切断と核－細胞質輸送変調の解析
- Author(s)
  北村朗，柴崎愛，油野祥子，金城政孝
- Organizer
  第37回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] ALS関連変異型TDP43に見られる構造変化と核－細胞質輸送変調の解析
- Author(s)
  北村朗，
- Organizer
  第２回　包括的神経グリア研究会
- Place of Presentation
  オースプラザ（愛知県名古屋市）
- Year and Date
  2015-01-10 – 2015-01-11
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] Analysis of structural difference in ALS-linked mutant of TDP-43 by fluorescence imaging in living cells.
- Author(s)
  油野祥子，北村朗，柴崎愛，金城政孝
- Organizer
  第52回　日本生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26440090
[Presentation] プロテアソーム活性阻害からの回復過程における細胞毒性発現機構の解明
- Author(s)
  北村朗，永田和宏，金城政孝
- Organizer
  2013年度若手イメージング研究会
- Place of Presentation
  東京理科大学野田キャンパス（千葉県）
- Data Source
  KAKENHI-PROJECT-23770215

1. KINJO Masataka (70177971)

# of Collaborated Projects: 5 results

# of Collaborated Products: 16 results
2. MIKUNI Shintaro (40435954)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KUBOTA HIROSHI (80332724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. NAGATA Kazuhiro (50127114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 野澤竜介 (70868710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUMOTO Gen

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. KABAYAMA Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 飛田成史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高橋俊太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kitamura Akira 北村 朗

KITAMURA Akira 北村 朗

北村 朗 キタムラ アキラ

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Establishing extreme spatio-temporal correlation spectroscopy for biological cluster analysisPrincipal Investigator

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蛍光動的消光測定による生細胞内RNA立体構造の情報物理解析Principal Investigator

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細胞由来微粒子迅速測定のための蛍光と散乱光測定の融合

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タンパク質2量体安定化機構へ与える細胞内微環境の影響解明

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Elucidation for chaperone RNAs that prevent protein aggregation associated with neurodegenerative diseases.Principal Investigator

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Elucidation for the regulation of motility and lifespan by proteostasis(Fostering Joint International Research)Principal Investigator

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Establishment of unified theory of cellular inclusion bodies including misfolded proteinPrincipal Investigator

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Regulation of cellular functions by highly evolved two chaperonins

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Analysis of neuronal cell death by ALS-associated misfolded protein aggregation with modulation of cellular RNA homeostasisPrincipal Investigator

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多点時空間相関解析法による細胞内分子複合体研究

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神経変性疾患を引き起こすタンパク質凝集体形成と神経細胞死機構の時空間的解析Principal Investigator

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Study of membrane binding protein complex using total internal reflection fluorescence correlation spectroscopy

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細胞質シャペロニンの機能解析Principal Investigator

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Kitamura Akira 北村朗

KITAMURA Akira 北村朗

北村朗キタムラアキラ