OHNO MIKIKO 大野美紀子

… Alternative Names

OHNO Mikiko 大野美紀子

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Researcher Number	10583198
Other IDs
Affiliation (Current)	2025: 滋賀医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 滋賀医科大学, 医学部, 准教授 2018 – 2023: 滋賀医科大学, 医学部, 准教授 2017: 滋賀医科大学, 医学部, 助教 2016: 京都大学, 医学研究科, 助教 2012 – 2016: 京都大学, 医学(系)研究科(研究院), 助教 2011: 京都大学, 医学(系)研究科(研究院), 研究員 2010 – 2011: 京都大学, 医学研究科, 特定助教
Review Section/Research Field	Principal Investigator Biological Sciences / Basic Section 53020:Cardiology-related / Cardiovascular medicine / Nerve anatomy/Neuropathology Except Principal Investigator Pathological medical chemistry / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 49010:Pathological biochemistry-related / Neuroscience in general
Keywords	Principal Investigator 細胞外ドメインシェディング / アルツハイマー病 / 多機能プロテアーゼ / 急性冠症候群 / メタロプロテアーゼ / 酵素活性 / 洞房結節自動能 / αセクレターゼ / 交感神経 / 心筋症 … More / 心拍数制御 / ナルディライジン / 巨核球 / 急性心筋梗塞 / 血小板産生制御 / 動脈硬化 / 血小板 / 洞房結節 / 循環器 / 転写制御 / プロテアーゼ / イオンチャネル / 洞不全症候群 / alpha-secretase / APP / AD (Alzheimer's disease) / α切断 / アミロイド前駆タンパク質 / 転写因子 / HCN / 心不全 / 血圧 / 心拍数 / 血管透過性 / in vivo imaging / バイオセンサーマウス / 血管収縮 / シェディング / アミロイドβ / 体温調節 / 循環動態 / アミロイドβ(Aβ) / 脱髄 / 多発性硬化症 … More Except Principal Investigator ナルディライジン / 恒常性 / 抗体産生 / エネルギー代謝 / 生体分子 / 細胞外ドメインシェディング / 循環動態 / メタロプロテアーゼ / 制御性T細胞 / 自己免疫疾患 / ペプチダーゼ / p53 / 転写 / 血小板 / 大腸がん / 糖代謝 / 転写コレギュレーター / インシュリン分泌 / 体温 / BACE1 / 低血圧 / 軸索成熟 / 徐脈 / 多発性硬化症 / アルツハイマー病 / 交感神経 / 髄鞘形成 Less

Investigation of proteases with multiple functions as novel therapeutic targets for autoimmune diseases
- Principal Investigator
  
  西英一郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Shiga University of Medical Science
多機能プロテアーゼの酵素活性による循環動態制御および心疾患における意義Principal Investigator
- Principal Investigator
  
  大野美紀子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Shiga University of Medical Science
Elucidation of the mechanism by which NRDC, a multifunctional protease, regulates platelet production and its significance as a diagnostic marker for ACS in the hyperacute phase.Principal Investigator
- Principal Investigator
  
  Mikiko Ohno
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Shiga University of Medical Science
Investigation of the mechanisms by which Multifaceted Homeostasis is maintained by Nardilysin
- Principal Investigator
  
  Nishi Eiichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Shiga University of Medical Science
Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticityPrincipal Investigator
- Principal Investigator
  
  Ohno Mikiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Shiga University of Medical Science
Investigation on the homeostatic regulation by NRDC-p53 axis
- Principal Investigator
  
  Nishi Eiichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Shiga University of Medical Science
Nardilysin regulates sinus automaticity through transcription of HCN.Principal Investigator
- Principal Investigator
  
  OHNO Mikiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kyoto University
M16メタロプロテアーゼによる脳タンパク質老化と認知症制御機構Principal Investigator
- Principal Investigator
  
  大野美紀子
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Investigation of the multifaceted roles of nardilysin in homeostatic maintenance
- Principal Investigator
  
  NIshi Eiichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
シェディング調節因子による血管収縮と透過性制御機構の解明Principal Investigator
- Principal Investigator
  
  大野美紀子
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
循環動態調節における交感神経分布様式の意義Principal Investigator
- Principal Investigator
  
  大野美紀子
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Nardilysin prevents amyloid plaque formation by enhancing alpha-secretase activity in an Alzheimer's disease mouse model.Principal Investigator
- Principal Investigator
  
  OHNO Mikiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University
新規シェディング活性化因子の交感神経―効果器ワイヤリングにおける意義の解明Principal Investigator
- Principal Investigator
  
  大野美紀子
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Pathophysiological roles of nardilysin, critical factor for axonal maturation and myelination
- Principal Investigator
  
  NISHI Eiichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Kyoto University
難治性神経疾患におけるシェディング調節因子の意義の解明Principal Investigator
- Principal Investigator
  
  大野美紀子
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University

[Book] 認知症学会誌 Dementia Japan2016
- Author(s)
  大野美紀子　西英一郎
- Total Pages
  5
- Publisher
  笹氣出版印刷
- Data Source
  KAKENHI-PROJECT-15K19376
[Book] 認知症学会誌　Dementia Japan2016
- Author(s)
  大野美紀子　西英一郎
- Total Pages
  5
- Publisher
  笹氣出版印刷
- Data Source
  KAKENHI-PUBLICLY-15H01557
[Journal Article] Nardilysin determines hematopoietic stem cell fitness by regulating protein synthesis2024
- Author(s)
  Oshima Shinichiro、Sinha Rahul、Ohno Mikiko、Nishi Kiyoto、Eto Koji、Takaori-Kondo Akifumi、Nishi Eiichiro、Yamamoto Ryo
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 693 Pages: 149355-149355
- DOI
  10.1016/j.bbrc.2023.149355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07550, KAKENHI-PROJECT-23K07966, KAKENHI-PROJECT-22K19428
[Journal Article] Auxiliary roles of nardilysin in the early diagnosis of acute coronary syndrome: a prospective cohort study, the Nardi-ACS study2024
- Author(s)
  Ohno M, Shiomi H, Baba O, Yano M, Aizawa T, Nakano-Matsumura Y, Yamagami S, Kato M, Ohya M, Chen PM, Nagao K, Ando K, Yokomatsu T, Kadota K, Kouchi I, Inada T, Valentine C, Kitagawa T, Kurokawa M, Ohtsuru S, Morimoto T, Kimura T, Nishi E
- Journal Title
  
  Internal and Emergency Medicine
  
  Volume: 19 Issue: 3 Pages: 649-659
- DOI
  10.1007/s11739-023-03508-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07550, KAKENHI-PROJECT-22K19428
[Journal Article] Subclinical myocardial damage after anthracycline chemotherapy in Japanese patients with breast cancer2024
- Author(s)
  Nakatsuma Kenji、Ozasa Neiko、Ohno Mikiko、Ishiguro Hiroshi、Minami Manabu、Nishi Eiichiro、Toi Masakazu、Ono Koh、Kimura Takeshi
- Journal Title
  
  Journal of Cardiology
  
  Volume: 0 Issue: 4 Pages: 0-0
- DOI
  10.1016/j.jjcc.2024.03.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07550, KAKENHI-PROJECT-22K19428
[Journal Article] Utility of atherosclerosis-associated serum antibodies against colony-stimulating factor 2 in predicting the onset of acute ischemic stroke and prognosis of colorectal cancer2023
- Author(s)
  Li SY, Yoshida Y, Kubota M, 他10名, Ohno M, Nishi E, Kitamura K, Kamitsukasa I, Takizawa H, Sata M, Yamagishi K, Iso H, Sawada N, Tsugane S, Iwase K, Shimada H, Iwadate Y, Hiwasa T.
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 10 Pages: 1-19
- DOI
  10.3389/fcvm.2023.1042272
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19428, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-20K07810, KAKENHI-PROJECT-20K08445, KAKENHI-PROJECT-23K07550, KAKENHI-PROJECT-20K17953
[Journal Article] Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis2022
- Author(s)
  Saijo S, Ohno M, Iwasaki H, Matsuda S, Nishi K, Hiraoka Y, Ide N, Kimura T, Nishi E.
- Journal Title
  
  Sci Rep.
  
  Volume: 12 Issue: 1 Pages: 3449-3449
- DOI
  10.1038/s41598-022-07379-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05958, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-20K08445, KAKENHI-PROJECT-21K20867, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-22H04922
[Journal Article] Deficiency of Nardilysin in the Liver Reduces Serum Cholesterol Levels2021
- Author(s)
  Yasuda Daisuke、Hiraoka Yoshinori、Ohno Mikiko、Nishi Kiyoto、Iwasaki Hirotaka、Kita Toru、Nishi Eiichiro、Kume Noriaki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 3 Pages: 363-371
- DOI
  10.1248/bpb.b20-00722
- NAID
  130007993442
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-20K08445
[Journal Article] Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke.2021
- Author(s)
  Hiwasa T, Wang H, Iwadate Y. et al
- Journal Title
  
  BMC Med
  
  Volume: 19 Issue: 1 Pages: 131-131
- DOI
  10.1186/s12916-021-02001-9
- NAID
  120007132378
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09451, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-17K16626, KAKENHI-PROJECT-19H03664, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-19K08596, KAKENHI-PROJECT-20K08445, KAKENHI-PROJECT-20K16436
[Journal Article] Elevated levels of autoantibodies against DNAJC2 in sera of patients with atherosclerotic diseases2020
- Author(s)
  Yoshida Y, Zhang XM, Wang H, Machida T, Iwadate Y, et al.
- Journal Title
  
  Heliyon
  
  Volume: 6 Issue: 8 Pages: e04661-e04661
- DOI
  10.1016/j.heliyon.2020.e04661
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09451, KAKENHI-PROJECT-20K07810, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-17K16626, KAKENHI-PROJECT-20K17953, KAKENHI-PROJECT-20H03449
[Journal Article] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor.2020
- Author(s)
  Ohno M, Nishi K, Hiraoka Y, Niizuma S, Matsuda S, Iwasaki H, Kimura K, and Nishi E
- Journal Title
  
  FASEB Journal
  
  Volume: 34 Issue: 9 Pages: 11624-11640
- DOI
  10.1096/fj.202000604r
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08445, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06280
[Journal Article] Serum anti-LRPAP 1 is a common biomarker for digestive organ cancers and atherosclerotic diseases2020
- Author(s)
  Sumazaki M, Shimada H, Ito M, Shiratori F, Iwadate Y, et al.
- Journal Title
  
  Cancer Sci
  
  Volume: 111 Issue: 12 Pages: 4453-4464
- DOI
  10.1111/cas.14652
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09451, KAKENHI-PROJECT-20K07810, KAKENHI-PROJECT-20K08445, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-17K16626, KAKENHI-PROJECT-20K16436, KAKENHI-PROJECT-20K17953, KAKENHI-PROJECT-20H03449
[Journal Article] Association between serum anti-ASXL2 antibody levels and acute aschemic stroke, acute myocardial infarction, diabetes mellitus, chronic kidney disease and digestive organ cancer, and their possible association with atherosclerosis and hypertension.2020
- Author(s)
  Li SY, Yoshida Y, Kobayashi E, Adachi A, Iwadate Y, et al.
- Journal Title
  
  Int J Mol Med
  
  Volume: 46 Pages: 1274-1288
- DOI
  10.3892/ijmm.2020.4690
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09451, KAKENHI-PROJECT-20K07810, KAKENHI-PROJECT-20K08445, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-17K16626, KAKENHI-PROJECT-20K17952, KAKENHI-PROJECT-20K17953, KAKENHI-PROJECT-20H03449
[Journal Article] Serum nardilysin, a surrogate marker for epithelial-mesenchymal transition, predicts prognosis of intrahepatic cholangiocarcinoma after surgical resection2019
- Author(s)
  Yoh T, Hatano E, Kasai Y, Fujii H, Nishi K, Toriguchi K, Sueoka H, Ohno M, Seo S, Iwaisako K, Taura K, Yamaguchi R, Kurokawa M, Fujimoto J, Kimura T, Uemoto S, and Nishi E.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 25(2) Issue: 2 Pages: 619-629
- DOI
  10.1158/1078-0432.ccr-18-0124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09575, KAKENHI-PROJECT-17K10510, KAKENHI-PUBLICLY-18H04694, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-16H06277
[Journal Article] Response to Letter of Stephenson et al.: Nardilysin: A potential biomarker for the early diagnosis of acute coronary syndrome2019
- Author(s)
  Ohno M, Chen PM, Kimura T, Nishi E.
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 277 Pages: 249-249
- DOI
  10.1016/j.ijcard.2018.10.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09575, KAKENHI-PUBLICLY-18H04694, KAKENHI-PROJECT-17H04048
[Journal Article] Reply: Nardilysin is a promising biomarker for the early diagnosis of acute coronary syndrome.2018
- Author(s)
  Chen PM, Ohno M, Kimura T, Nishi E.
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 265 Pages: 236-236
- DOI
  10.1016/j.ijcard.2018.04.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09575, KAKENHI-PUBLICLY-18H04694, KAKENHI-PROJECT-17H04048
[Journal Article] Nardilysin controls intestinal tumorigenesis through HDAC1/p53?dependent transcriptional regulation2018
- Author(s)
  Kanda Keitaro、Sakamoto Jiro、Matsumoto Yoshihide、Ikuta Kozo、Goto Norihiro、Morita Yusuke、Ohno Mikiko、Nishi Kiyoto、Chiba Tsutomu、Nishi Eiichiro、Seno Hiroshi
- Journal Title
  
  JCI Insight
  
  Volume: 3 Issue: 8 Pages: 1-15
- DOI
  10.1172/jci.insight.91316
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09575, KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-15J03212, KAKENHI-PROJECT-16K15216, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-17H04157, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-18H04164
[Journal Article] Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production.2018
- Author(s)
  Ito Y, Nakamura S, Sugimoto N, Shigemori T, Kato Y, Ohno M, Sakuma S, Ito K, Kumon H, Hirose H, Okamoto H, Nogawa M, Iwasaki M, Kihara S, Fujio K, Matsumoto T, Higashi N, Hashimoto K, Sawaguchi A, Harimoto KI, Nakagawa M, Yamamoto T, Handa M, Watanabe N, Nishi E, Arai F, Nishimura S, Eto K.
- Journal Title
  
  Cell
  
  Volume: 174(3) Issue: 3 Pages: 636-648
- DOI
  10.1016/j.cell.2018.06.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09575, KAKENHI-PUBLICLY-18H04694, KAKENHI-PROJECT-16H05156, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18H04164
[Journal Article] Elevation of autoantibody level against PDCD11 in patients with transient ischemic attack2017
- Author(s)
  Yoshida Y、Wang H、Hiwasa T、Machida T、Kobayashi E、Mine S、Tomiyoshi G、Nakamura R、Shinmen N、Kuroda H、Takizawa H、Kashiwado K、Kamitsukasa I、Shin H、Wada T、Aotsuka A、Nishi E、Ohno M、Takemoto M、Yokote K、Takahashi S、Matsushima J、Zhang Xiao-Meng、Takiguchi M、Iwadate Y
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 10 Pages: 8836-8848
- DOI
  10.18632/oncotarget.23653
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09229, KAKENHI-PROJECT-17K19643, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-16K15216
[Journal Article] Nardilysin promotes hepatocellular carcinoma through activation of signal transducer and activator of transcription 32017
- Author(s)
  Kasai Y, Toriguchi K, *Hatano E, Nishi K, Ohno M, Yoh T, Fukuyaman K, Nishio T, Okuno M, Iwaisako K, Seo S, Taura K, Kurokawa M, Kunichika M, Uemoto S, *Nishi E
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Issue: 5 Pages: 910-917
- DOI
  10.1111/cas.13204
- NAID
  120006333898
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293068, KAKENHI-PROJECT-26461909, KAKENHI-PROJECT-15K19513, KAKENHI-PROJECT-16K15216, KAKENHI-PROJECT-17K09575, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-17K16147
[Journal Article] Genome-wide profiling of nardilysin target genes reveals its role in epigenetic regulation and cell cycle progression2017
- Author(s)
  Morita Y, Ohno M, Nishi K, Hiraoka Y, Saijo S, Matsuda S, Kita T, Kimura T, Nishi E.
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 14801-14801
- DOI
  10.1038/s41598-017-14942-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08536, KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-16J09377, KAKENHI-PROJECT-16K15216
[Journal Article] Nardilysin is involved in autoimmune arthritis via the regulation of tumour necrosis factor alpha secretion2017
- Author(s)
  Fujii Takayuki、Nishi Eiichiro、Ito Hiromu、Yoshitomi Hiroyuki、Furu Moritoshi、Okabe Namiko、Ohno Mikiko、Nishi Kiyoto、Morita Yusuke、Morita Yugo、Azukizawa Masayuki、Okahata Akinori、Tomizawa Takuya、Kimura Takeshi、Matsuda Shuichi
- Journal Title
  
  RMD Open
  
  Volume: 3 Issue: 1 Pages: e000436-e000436
- DOI
  10.1136/rmdopen-2017-000436
- NAID
  120006325113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09575, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-16K15216, KAKENHI-PROJECT-17K16147
[Journal Article] Association of serum levels of antibodies against MMP1, CBX1, and CBX5 with transient ischemic attack and cerebral infarction2017
- Author(s)
  Wang H,Zhang X-M,Tomiyoshi G,Nakamura R,Shinmen N,Kuroda H,Kimura R,Mine S,Kamitsukasa I,Wada T,Aotsuka A,Yoshida Y,Kobayashi E,Matsutani T,Iwadate Y,Sugimoto K,Mori M,Uzawa A,Muto M,Kuwabara S,Takemoto M,Kobayashi K,Kawamura H,Ishibashi R,Yokote K,Ohno M,
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 5 Pages: 5600-5613
- DOI
  10.18632/oncotarget.23789
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09229, KAKENHI-PROJECT-16K09691, KAKENHI-PROJECT-16K10750, KAKENHI-PROJECT-17K09575, KAKENHI-PROJECT-17H01558, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-15K09333, KAKENHI-PROJECT-16K15216
[Journal Article] Loss of Nardilysin, a mitochondrial co-chaperone for α-Ketoglutarate Dehydrogenase, promotes mTORC1 activation and neurodegeneration.2017
- Author(s)
  Yoon W.H., Sandoval H.,Nagarkar-Jaiswal S.,Jaiswal M.,Yamamoto S., Haelterman N.A., Putluri N., Putluri V., Sreekumar A., Tos T., Aksoy A., Donti T., Graham B.H., Ohno M.,　Nishi E.,　Hunter J.,　Muzny D.M.,Carmichael J.,Shen J.,Arboleda V.A.,Nelson S.F.,Wangler M.F.,Karaca E.,Lupski J.R.,Bellen H.
- Journal Title
  
  Neuron
  
  Volume: 93 Issue: 1 Pages: 115-131
- DOI
  10.1016/j.neuron.2016.11.038
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01557, KAKENHI-PROJECT-26293068, KAKENHI-PROJECT-16K15216
[Journal Article] Nardilysin is a promising biomarker for the early diagnosis of acute coronary syndrome2017
- Author(s)
  Chen Po-Min、Ohno Mikiko、Hiwasa Takaki、Nishi Kiyoto、Saijo Sayaka、Sakamoto Jiro、Morita Yusuke、Matsuda Shintaro、Watanabe Shin、Kuwabara Yasuhide、Ono Koh、Imai Masao、Inoue Katsumi、Murai Tatsuya、Inada Tsukasa、Tanaka Masaru、Kita Toru、Kimura Takeshi、Nishi Eiichiro
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 243 Pages: 1-8
- DOI
  10.1016/j.ijcard.2017.04.047
- NAID
  130007900462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09575, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-16K15216, KAKENHI-PROJECT-17K16147
[Journal Article] Nardilysin is required for maintaining pancreatic β-Cell Function.2016
- Author(s)
  Nishi K, Sato Y, Ohno M, Hiraoka Y, Saijo S, Sakamoto J, Chen P-M, Morita Y, Matsuda S, Iwasaki K, Sugizaki K, Harada N, Mukumoto Y, Kiyonari H, Furuyama K, Kawaguchi Y, Uemoto S, Kita T, Inagaki N, Kimura T and Nishi E
- Journal Title
  
  Diabetes
  
  Volume: 65 Issue: 10 Pages: 3015-3027
- DOI
  10.2337/db16-0178
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01557, KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-26293068, KAKENHI-PROJECT-15K19376, KAKENHI-PROJECT-15K19513, KAKENHI-PROJECT-16K09745, KAKENHI-PROJECT-16K15216
[Journal Article] アルツハイマー病におけるαセクレターゼの活性制御2016
- Author(s)
  大野美紀子、西英一郎
- Journal Title
  
  認知症学会誌Dementia Japan
  
  Volume: 30 Pages: 174-183
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01557
[Journal Article] Critical roles of nardilysin in the maintenance of body temperature homoeostasis.2014
- Author(s)
  Hiraoka Y, Matsuoka T, Ohno M, Nakamura K, Saijo S, Matsumura S, Nishi K, Sakamoto J, Chen PM, Inoue K, Fushiki T, Kita T, Kimura T and Nishi E.
- Journal Title
  
  Nature Communications
  
  Volume: 5 Pages: 3224-3224
- NAID
  120005367798
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113710
[Journal Article] Critical roles of nardilysin in the maintenance of body temperature homeostasis2014
- Author(s)
  Hiraoka Y, Matsuoka T, Ohno M, Nakamura K, Saijo S, Matsumura S, Nishi K, Sakamoto J, Chen Po-Min, Inoue K, Fushiki T, Kita T, Kimura T and Nishi E
- Journal Title
  
  Nat. Commun
  
  Volume: 5 Issue: 1 Pages: 3224-3224
- DOI
  10.1038/ncomms4224
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300117, KAKENHI-PUBLICLY-24113713, KAKENHI-PUBLICLY-25122709, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25670118
[Journal Article] Critical roles of nardilysin in the maintenance of body temperature homoeostasis2014
- Author(s)
  Hiraoka Y, Matsuoka T, Ohno M, Nakamura K, Saijo S, Matsumura S, Nishi K, Sakamoto J, Chen PM, Inoue K, Fushiki T, Kita T, Kimura T and Nishi E.
- Journal Title
  
  Nat Commun
  
  Volume: 5 Pages: 3224-3224
- NAID
  120005367798
- Data Source
  KAKENHI-PROJECT-24700366
[Journal Article] Nardilysin prevents amyloid plaque formation by enhancingα-secretase activity in an Alzheimer's disease mouse model2014
- Author(s)
  Ohno M, Hiraoka Y, Lichtenthaler S.F, Nishi K, Saijo S, Matsuoka T, Tomimoto H, Araki W, Takahashi R, Kita T, Kimura T and Nishi E.
- Journal Title
  
  Neurobiol Aging
  
  Volume: 35(1) Pages: 213-22
- Data Source
  KAKENHI-PROJECT-24700366
[Journal Article] Nardilysin prevents amyloid plaque formation by enhancing a-secretase activity in an Alzheimer's disease mouse model2014
- Author(s)
  Ohno M, Hiraoka Y, Lichtenthaler S, Nishi K, Saijo S, Matsuoka T, Tomimoto H, Araki W, Takahashi R, Kita T, Kimura T and Nishi E
- Journal Title
  
  Neurobiol Aging
  
  Volume: 35 Issue: 1 Pages: 213-22
- DOI
  10.1016/j.neurobiolaging.2013.07.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300117, KAKENHI-PROJECT-23390232, KAKENHI-PUBLICLY-24113713, KAKENHI-PROJECT-24700366, KAKENHI-PUBLICLY-25113710, KAKENHI-PUBLICLY-25122709, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25670118
[Journal Article] Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signaling via enhanced ectodomain shedding of TNF-a2012
- Author(s)
  Kanda K, Komekado H, Kawada M, et al
- Journal Title
  
  EMBO Molecular Medicine
  
  Volume: (印刷中) Issue: 5 Pages: 396-411
- DOI
  10.1002/emmm.201200216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J40033, KAKENHI-PROJECT-10J02434, KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-22790641, KAKENHI-PUBLICLY-23122510, KAKENHI-PROJECT-23300117, KAKENHI-PROJECT-23590937, KAKENHI-PROJECT-23659154, KAKENHI-PROJECT-23659755, KAKENHI-PROJECT-24590914, KAKENHI-PROJECT-24659363, KAKENHI-PROJECT-24700366, KAKENHI-PUBLICLY-23117519, KAKENHI-PUBLICLY-24113713
[Journal Article] Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signaling via enhanced ectodomain shedding of TNF-α2012
- Author(s)
  Kanda K, Komekado H, Sawabu T, Ishizu S, Nakanishi Y, Nakatsuji M, Akitake-Kawano R, Ohno M, Hiraoka Y, Kawada M, Kawada K, Sakai Y, Matsumoto K, Kunichika M, Kimura T, Seno H, Nishi E and Chiba T.
- Journal Title
  
  EMBO Mol Med
  
  Volume: 4(5) Pages: 396-411
- Data Source
  KAKENHI-PROJECT-24700366
[Presentation] M16メタロエンドペプチダーゼによる心拍数制御機構2024
- Author(s)
  大野美紀子、松浦博、西清人、糀谷泰彦、牧山武、池田真也、西英一郎
- Organizer
  第33回循環薬理学会
- Data Source
  KAKENHI-PROJECT-23K07550
[Presentation] 多機能タンパク質ナルディライジン酵素活性の中枢神経系における意義解明2024
- Author(s)
  大野美紀子、江角重行、大林徹也、西清人、荒木喜美、西英一郎
- Organizer
  先端モデル動物支援プラットフォーム（AdAMS）「2023年度成果発表会」
- Data Source
  KAKENHI-PROJECT-23K07550
[Presentation] 多機能プロテアーゼによる循環動態制御機構2023
- Author(s)
  大野美紀子
- Organizer
  第28回日本病態プロテアーゼ学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K07550
[Presentation] Enzymatic activity of nardilysin plays significant roles in the regulation of central nervous system activity.2023
- Author(s)
  Mikiko Ohno, Shigeyuki Esumi, Tetsuya Obayashi, Takayuki Fujii, Kiyoto Nishi, Shinya Ikeda, Eiichiro Nishi
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K07550
[Presentation] タコツボ症候群における多機能プロテアーゼの役割2023
- Author(s)
  大野　美紀子、西　清人、西　英一郎
- Organizer
  第32回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] タコツボ症候群における多機能プロテアーゼの役割2022
- Author(s)
  大野　美紀子、西　清人、西　英一郎
- Organizer
  第32回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] ナルディライジン酵素活性の生体内における意義2022
- Author(s)
  大野美紀子, 松浦博, 牧山武, 糀谷泰彦, 西清人, 西英一郎
- Organizer
  第27回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] 多機能プロテアーゼによる洞機能制御機構2022
- Author(s)
  大野美紀子, 松浦博, 牧山武, 糀谷泰彦, 西清人, 西英一郎
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Nardilysin in hepatocyte regulates diet-induced thermogenesis via the modulation of brown adipose tissue activity2022
- Author(s)
  Kiyoto Nishi、Hirotaka Iwasaki、Mikiko Ohno、Shintaro Matsuda、Eiichiro Nishi
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] 多機能プロテアーゼによる洞機能制御機構2022
- Author(s)
  大野美紀子, 松浦博, 牧山武, 糀谷泰彦, 西清人, 西英一郎
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] ナルディライジン酵素活性の生体内における意義2022
- Author(s)
  大野美紀子, 松浦博, 牧山武, 糀谷泰彦, 西清人, 西英一郎
- Organizer
  第27回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] ナルディライジンによる抗体産生調節機構の解明およびDSS腸炎モデルでの検討2022
- Author(s)
  茶谷　元晴, 藤井　貴之, 藤堂　景史, 大野　美紀子, 西　清人, 平田　多佳子, 西　英一郎, 安藤　朗
- Organizer
  第59回日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] TおよびB細胞のナルディライジンによる抗体産生調節機構の解明2021
- Author(s)
  茶谷元晴, 茶谷元晴, 藤井貴之, 藤堂景史, 大野美紀子, 西清人, 平田多佳子, 安藤朗, 西英一郎
- Organizer
  第26回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] 脂肪細胞のNardilysinは細胞における酸素需要および低酸素誘導因子（HIF1-α）シグナルを介してインスリン感受性を制御する2021
- Author(s)
  松田真太郎、岩﨑広高、西清人、大野美紀子、西英一郎
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] 多機能プロテアーゼによる心拍数制御機構2021
- Author(s)
  大野美紀子, 松浦博, 牧山武, 糀谷泰彦, 西清人, 岩崎広高, 松田真太郎, 木村剛, 西英一郎
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Nardilysin is a Potential Biomarker for the Early Diagnosis of Non-St-Segment Elevation Acute Coronary Syndrome, A Multicenter Prospective Cohort Study, Nardi-ACS Study2021
- Author(s)
  Ohno M, Shiomi H, Yano M, Aizawa T, Nakano Y, Yamagami S, Kato M, Ohya M, Chen P-M, Nagao K, Ando K, Kadota K, Yokomatsu T, Inada T, Kurokawa M, Morimoto T, Kimura T, Nishi E
- Organizer
  American Heart Association’s annual Scientific Sessions 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2021
- Author(s)
  Ohno M, Matsuura H, Makiyama T, Nishi K, Iwasaki T, Matsuda S, Kita T, Kimura T, and Nishi E
- Organizer
  第31回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] 肝細胞のナルディライジンは褐色脂肪組織の熱産生を制御する2021
- Author(s)
  西清人, 岩崎広高, 松田真太郎, 大野美紀子, 西英一郎
- Organizer
  日本動脈硬化学会総会
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] Nardilysin is a Potential Biomarker for the Early Diagnosis of Non-St-Segment Elevation Acute Coronary Syndrome, A Multicenter Prospective Cohort Study, Nardi-ACS Study2021
- Author(s)
  Mikiko Ohno, hiroki shiomi, Mariko Yano, Takanori Aizawa, Yukiko Nakano, Shintaro Yamagami, Masashi Kato, Masanobu Ohya, Po-Min Chen, Kazuya Nagao, Kenji Ando, Kazushige Kadota, Takafumi Yokomatsu, Inada Tsukasa, masato kurokawa, Takeshi Morimoto, Takeshi Kimura and Eiichiro Nishi
- Organizer
  American Heart Assocication, Scientific sessions 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] NRDCはイオンチャンネルの転写調節を介して洞の自動性を調節する2021
- Author(s)
  大野美紀子, 松浦博, 牧山武, 糀谷泰彦, 西清人, 松田真太郎, 木村剛, 西英一郎
- Organizer
  日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] 肝細胞のナルディライジンは褐色脂肪組織の熱産生を制御する2021
- Author(s)
  西清人, 岩崎広高, 松田真太郎, 松田真太郎, 大野美紀子, 西英一郎
- Organizer
  第53回日本動脈硬化学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] 脂肪細胞のNardilysinは脂肪組織の酸素需要およびインスリン感受性を制御する2020
- Author(s)
  松田真太郎、岩﨑広高、大野美紀子、西英一郎
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Nardilysin in hepatocyte regulates adaptive thermogenesis in brown adipose tissue through the control of skin blood flow2020
- Author(s)
  Iwasaki H, Nishi K, Imai T, Yasukawa D, Chatani M, Matsuda S, Ohno M, Nishi E
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] ナルディライジンによるPER2を介した概日リズム制御機構の解明2020
- Author(s)
  平岡義範、吉種光、大野美紀子、森田雄介、布川莉奈、西清人、久米典昭、木村剛、深田吉孝、西英一郎
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2020
- Author(s)
  Ohno M, Matsuura H., Makiyama T., Nishi K., Iwasaki H., Matsuda S., Kita T., Kimura T., and Nishi E.
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] トピックス：心筋症2　たこつぼ症候群を再考する2020
- Author(s)
  大野美紀子
- Organizer
  第84回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor.2020
- Author(s)
  Ohno M, Nishi K, Hiraoka Y, Niizuma S, Matsuda S, Iwasaki H, Kimura K, and *Nishi E
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2020
- Author(s)
  Ohno M, Matsuura H., Makiyama T., Nishi K., Iwasaki H., Matsuda S., Kita T., Kimura T., and Nishi E.
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] 多機能プロテアーゼによる心拍数制御機構2020
- Author(s)
  大野美紀子、松浦博、西清人、牧山武、糀谷泰彦、岩崎広高、松田真太郎、西英一郎
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor.2020
- Author(s)
  Ohno M, Nishi K, Hiraoka Y, Niizuma S, Matsuda S, Iwasaki H, Kimura K, and Nishi E
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor2020
- Author(s)
  Ohno M, Nishi K, Hiraoka Y, Niizuma S, Matsuda S, Iwasaki H, Kimura K, and Nishi E
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor.2020
- Author(s)
  Ohno M, Nishi K, Hiraoka Y, Niizuma S, Matsuda S, Iwasaki H, Kimura K, and *Nishi E
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] ナルディライジンはp75NTRの調節を介して心臓交感神経分布パターンを調節する2020
- Author(s)
  大野美紀子、西　清人、平岡　義範、新妻　晋一朗、岩崎　広高、松田　真太郎、木村　剛、西　英一郎
- Organizer
  第30回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-20K08445
[Presentation] ナルディライジンはp75NTRの調節を介して心臓交感神経分布パターンを調節する2020
- Author(s)
  大野美紀子、西　清人、平岡　義範、新妻　晋一朗、岩崎　広高、松田　真太郎、木村　剛、西　英一郎
- Organizer
  第30回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Nardilysin in Adipocyte Regulates Adipose Tissue Inflammation and Insulin Sensitivity2020
- Author(s)
  松田真太郎、西清人、大野美紀子、西英一郎
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] 多機能プロテアーゼによる心拍数制御機構2019
- Author(s)
  大野美紀子、松浦博、西清人、牧山武、糀谷泰彦、岩崎広高、松田真太郎、西英一郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 肝細胞のナルディライジンは皮膚血流調節を介して適応熱産生を制御する2019
- Author(s)
  岩﨑広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第56回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2019
- Author(s)
  Ohno M, Matsuura H., Makiyama T., Nishi K., Iwasaki H., Matsuda S., Kita T., Kimura T., and Nishi E.
- Organizer
  ESC congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 多機能プロテアーゼによる心拍数制御機構2019
- Author(s)
  大野美紀子、松浦博、西清人、岩崎広高、松田真太郎、西英一郎
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 肝臓ナルディライジンは皮膚血流調節を介して適応熱産生を制御する2019
- Author(s)
  岩﨑広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第51回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 肝臓はナルディライジンの発現調節を通じ食事誘導性熱産生を制御する2019
- Author(s)
  岩﨑広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第40回日本肥満学会・第37回日本肥満症治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Nardilysin in adipocyte regulates adipose tissue inflammation and insulin sensitivity2019
- Author(s)
  Matsuda S, Nishi K, Iwasaki H, Ohno M, Kimura T, and Nishi E
- Organizer
  第83回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2019
- Author(s)
  Ohno M, Matsuura H, Makiyama T, Iwasaki H, Matsuda S, and Nishi E
- Organizer
  第83回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 肝臓ナルディライジンは皮膚血流調節を介して適応熱産生を制御する2019
- Author(s)
  岩﨑広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第24回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2019
- Author(s)
  Ohno M, Matsuura H., Makiyama T., Nishi K., Iwasaki H., Matsuda S., Kita T., Kimura T., and Nishi E.
- Organizer
  ESC congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09575
[Presentation] 肝細胞のナルディライジンは栄養を感知し褐色組織細胞の適応熱産生を制御する2019
- Author(s)
  岩崎広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 肝臓はナルディライジンの発現調節を通じ食事誘導生熱産生を制御する2019
- Author(s)
  岩﨑広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2019
- Author(s)
  Ohno M, Matsuura H., Makiyama T., Nishi K., Iwasaki H., Matsuda S., Kita T., Kimura T., and Nishi E.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K09575
[Presentation] Nardilysin is a critical component of the mammalian circadian negative feedback loop.2019
- Author(s)
  Hiraoka Y, Yoshitane H, Ohno M, Morita Y, Nunokawa R, Nishi K, Kume N, Kimura T, Fukada Y, and Nishi E
- Organizer
  XVI European Biological Rhythms Society Congress (EBRS2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 肝細胞に発現するペプチダーゼによる熱放散を介した食事誘導性熱産生制御機構2019
- Author(s)
  岩﨑広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 脂肪細胞のナルディライジンは脂肪組織慢性炎症およびインスリン感受性を制御する2019
- Author(s)
  松田真太郎、岩﨑広高、西清人、大野美紀子、西英一郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2019
- Author(s)
  Mikiko Ohno,　Hiroshi Matsuura,　Takeru Makiyama,　Hirotaka Iwasaki,　Shintaro Matsuda, Eiichiro Nishi
- Organizer
  第83回日本循環器学会総会
- Data Source
  KAKENHI-PROJECT-17K09575
[Presentation] A metalloendopeptidase, nardilysin in hepatocyte regulates adaptive thermogenesis in brown adipose tissue2019
- Author(s)
  Nishi E, Iwasaki H, Nishi K, Ohno M, Matsuda S
- Organizer
  11th General Meeting of the International Proteolysis Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Nardilysin in hepatocyte regulates adaptive thermogenesis in brown adipose tissue2018
- Author(s)
  Nishi E, Iwasaki H, Nishi K, Ohno M, Matsuda S
- Organizer
  9th FAOPS Congress (Federation of the Asian and Oceanian Physiological Science)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 脂肪細胞のナルディライジンはケモカイン発現調節を介して脂肪組織慢性炎症およびインスリン感受性を制御する2018
- Author(s)
  松田真太郎、岩﨑広高、西清人、木村剛、大野美紀子、西英一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Nardilysin regulates cardiac dynamics and cardiac sympathetic innervation through modulating p75NTR shedding2018
- Author(s)
  大野美紀子, 西清人, 平岡義範, 新妻晋一郎, 西城さやか, 坂本二郎, 陳博俊, 森田雄介, 松田真太郎, 椋本淑子, 清成寛, 松浦博, 北徹, 木村剛, 西英一郎.
- Organizer
  神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09575
[Presentation] 肝臓ナルディライジンの発現調節による食事誘導性熱産生の制御2018
- Author(s)
  岩﨑広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Nardilysin is a Promising Biomarker for the Early Diagnosis of Acute Coronary Syndrome.2018
- Author(s)
  Ohno M, Chen P-M, Hiwasa T, Nishi K, Saijo S, Sakamoto J, Morita Y, Watanabe S, Kuwabara Y, Ono K, Imai M, Inoue K, Murai T, Kita T, Kimura T, and Nishi E.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09575
[Presentation] 肝細胞のナルディライジンは神経系を介して褐色脂肪組織の熱産生を制御する2018
- Author(s)
  岩﨑広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第23回日本病態プロテアーゼ学会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 肝臓ナルディライジンによる皮膚血流調節を介した適応熱産生制御2018
- Author(s)
  岩﨑広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第28回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Nardilysin regulates cardiac dynamics and cardiac sympathetic innervation through modulating p75NTR shedding2018
- Author(s)
  大野美紀子, 西清人, 平岡義範, 新妻晋一郎, 西城さやか, 坂本二郎, 陳博俊, 森田雄介, 松田真太郎, 椋本淑子, 清成寛, 松浦博, 北徹, 木村剛, 西英一郎.
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Nardilysin, a new PER2-interacting protein, regulates the mammalian circadian clock2018
- Author(s)
  Hiraoka Y, Yoshitane H, Ohno M, Morita Y,Nunokawa R, Nishi K, Kume N, Kimura T, Fukada Y and Nishi E
- Organizer
  The 43rd FEBS Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 多機能プロテアーゼによる心拍数制御機構2018
- Author(s)
  大野美紀子、松浦博、西清人、岩崎広高、松田真太郎、西英一郎
- Organizer
  第28回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 肝細胞のナルディライジンは肝臓迷走神経を介して褐色脂肪組織の熱産生を制御する2018
- Author(s)
  岩﨑広高、西清人、松田真太郎、大野美紀子、西英一郎
- Organizer
  第61回日本糖尿病学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] MicroRNA-494 plays a role in fiber type-specific skeletal myogenesis by targeting transcriptional coactivator p300 in human induced pluripotent stem cells2018
- Author(s)
  Iwasaki H, Morino K, Ohno M, Sakurai H, Maegawa H, Nishi E, Imamura T
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Nardilysin is a Promising Biomarker for the Early Diagnosis of Acute Coronary Syndrome.2018
- Author(s)
  Ohno M, Chen P-M, Hiwasa T, Nishi K, Saijo S, Sakamoto J, Morita Y, Watanabe S, Kuwabara Y, Ono K, Imai M, Inoue K, Murai T, Kita T, Kimura T, and Nishi E.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Nardilysin Critically Regulates Insulin Secretion and Glucose Metabolism2017
- Author(s)
  Nishi K, Ohno M, Saijo S, Morita Y, Matsuda S, Sakamoto J, Chen P, Kimura T, Nishi E.
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] ナルディライジンによるp75NTRシェディングを介する心臓交感神経分布パターンの決定2017
- Author(s)
  西　英一郎、大野　美紀子
- Organizer
  第40回日本神経科学大会　NEUROSCIENCE2017
- Invited
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 急性冠症候群における新規バイオマーカー「ナルディライジン」の有用性についての検討2017
- Author(s)
  大野美紀子、陳博俊、日和佐隆樹、西清人、西城さやか、森田雄介、松田真太郎、木村剛、西英一郎.
- Organizer
  第22回日本病態プロテアーゼ学会
- Data Source
  KAKENHI-PROJECT-17K09575
[Presentation] ナルディライジンによるPER2の機能調節を介した概日リズム制御機構2017
- Author(s)
  平岡義範、吉種光、大野美紀子, 森田雄介、布川莉奈、西清人、久米典昭、木村剛、深田吉孝、西英一郎
- Organizer
  生命科学系学会合同年次大会(第40回日本分子生物学会年会)
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] ナルディライジンは神経栄養因子受容体(p75NTR)のシェディングを介して心臓交感神経の分布を制御する2017
- Author(s)
  大野美紀子, 西清人, 平岡義範, 新妻晋一郎, 西城さやか, 坂本二郎, 陳博俊, 森田雄介, 松田真太郎, 椋本淑子, 清成寛, 松浦博, 北徹, 木村剛, 西英一郎.
- Organizer
  生命科学系学会合同年次大会(第40回日本分子生物学会年会)
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] アルツハイマー病におけるNardilysin(NRDC)とその関連分子の発現解析2017
- Author(s)
  大野　美紀子
- Organizer
  新学術領域研究（研究領域提案型）脳タンパク質老化と認知症制御　第5回班員会議
- Place of Presentation
  ウインクあいち（愛知県名古屋市）
- Data Source
  KAKENHI-PUBLICLY-15H01557
[Presentation] 脂肪組織のナルディライジンはインスリン感受性を制御する2017
- Author(s)
  松田真太郎, 森田雄介, 岩﨑広高, 大野美紀子, 木村剛, 西英一郎
- Organizer
  Molecular Cardiovascular Metabolic Conference 2017
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] ゲノムワイド統合解析によるナルディライジンの細胞周期制御機構の解明2017
- Author(s)
  森田雄介, 大野美紀子, 西清人, 西城さやか, 松田真太郎, 木村剛, 西英一郎
- Organizer
  第22回日本病態プロテアーゼ学会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] ナルディライジンは神経栄養因子受容体(p75NTR)のシェディングを介して心臓交感神経の分布を制御する2017
- Author(s)
  大野美紀子, 西清人, 平岡義範, 新妻晋一郎, 西城さやか, 坂本二郎, 陳博俊, 森田雄介, 松田真太郎, 椋本淑子, 清成寛, 松浦博, 北徹, 木村剛, 西英一郎
- Organizer
  生命科学系学会合同年次大会(第40回日本分子生物学会年会)
- Data Source
  KAKENHI-PROJECT-17K09575
[Presentation] 急性冠症候群における新規バイオマーカー「ナルディライジン」の有用性についての検討2017
- Author(s)
  大野美紀子、陳博俊、日和佐隆樹、西清人、西城さやか、森田雄介、松田真太郎、木村剛、西英一郎
- Organizer
  第22回日本病態プロテアーゼ学会
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 基礎と臨床の橋渡しを目指して～新規ACSバイオマーカーの開発～2017
- Author(s)
  大野美紀子
- Organizer
  第81回日本循環器学会学術集会　第１回Travel Award for Women Cardiologists
- Place of Presentation
  石川県立音楽堂外（石川県金沢市）
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K19376
[Presentation] 多機能タンパク質NardilysinのACSバイオマーカーとしての意義2017
- Author(s)
  大野美紀子
- Organizer
  第3回Cardiac Biomarker研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09575
[Presentation] Nardilysin is a Promising Biomarker for the Early Diagnosis of Acute Coronary Syndrome.2017
- Author(s)
  Ohno M, Chen P-M, Hiwasa T, Nishi K, Saijo S, Sakamoto J, Morita Y, Watanabe S, Kuwabara Y, Ono K, Imai M, Inoue K, Murai T, Kita T, Kimura T, and Nishi E.
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  石川県立音楽堂外（石川県金沢市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K19376
[Presentation] MicroRNA-494は転写共役因子p300を介して筋線維型特異的ヒト骨格筋細胞分化を制御する2017
- Author(s)
  岩﨑広高、今村武史、森野勝太郎、櫻井英俊、大野美紀子、前川聡、西英一郎
- Organizer
  生命科学系学会合同年次大会(第40回日本分子生物学会年会)
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] Nardilysin-mediated epigenetic regulation contributes to the cell cycle progression and proliferation in mouse embryonic fibroblasts2017
- Author(s)
  森田雄介, 大野美紀子, 西清人, 西城さやか, 松田真太郎, 木村剛, 西英一郎
- Organizer
  生命科学系学会合同年次大会(第40回日本分子生物学会年会)
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] 脂肪細胞のナルディライジンはインスリン感受性および脂肪組織の慢性炎症を制御する2017
- Author(s)
  松田真太郎, 森田雄介, 岩﨑広高, 大野美紀子, 木村剛, 西英一郎
- Organizer
  生命科学系学会合同年次大会(第40回日本分子生物学会年会)
- Data Source
  KAKENHI-PROJECT-17H04048
[Presentation] M16メタロプロテアーゼによる脳タンパク質老化と認知症制御機構2016
- Author(s)
  大野　美紀子
- Organizer
  新学術領域研究（研究領域提案型）脳タンパク質老化と認知症制御　第4回班員会議および第2回リトリート
- Place of Presentation
  サンルートプラザ東京（千葉県浦安市）
- Year and Date
  2016-06-03
- Data Source
  KAKENHI-PUBLICLY-15H01557
[Presentation] Nardilysin is a Promising Biomarker for the Early Diagnosis of Acute Coronary Syndrome.2016
- Author(s)
  Ohno M, Chen P-M, Hiwasa T, Nishi K, Saijo S, Sakamoto J, Morita Y, Watanabe S, Kuwabara Y, Ono K, Imai M, Inoue K, Murai T, Kita T, Kimura T, and Nishi E.
- Organizer
  American Heart Association Scientific Session
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin is a Promising Biomarker for the Early Diagnosis of Acute Coronary Syndrome.2016
- Author(s)
  Ohno M, Chen P-M, Hiwasa T, Nishi K, Saijo S, Sakamoto J, Morita Y, Watanabe S, Kuwabara Y, Ono K, Imai M, Inoue K, Murai T, Kita T, Kimura T, and Nishi E.
- Organizer
  American Heart Association Scientific Sessions
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19376
[Presentation] ナルディライジンによる交感神経系を介した循環動態の制御2015
- Author(s)
  大野美紀子、平岡義範、松浦博、西清人、西城さやか、坂本二郎、陳博敏、森田雄介、北徹、木村剛、西英一郎
- Organizer
  第16回日本循環制御医学会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin, a Potent Biomarker for Acute Coronary Syndrome, Regulates Postmyocardial Infarction Remodeling2015
- Author(s)
  Chen PM, Ohno M, Nishi K, Saijo S, Sakamoto J, Morita Y, Kimura T, Nishi E.
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] ナルディライジンは膵β細胞機能、分化の維持に必須である2015
- Author(s)
  西清人、佐藤雄一、大野美紀子、平岡義範、西城さやか、坂本二郎、陳博敏、森田雄介、松田真太郎、北徹、稲垣暢也、木村剛、西英一郎
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin in brown adipose tissue regulates adaptive thermogenesis and body temperature homeostasis.2015
- Author(s)
  Saijo S, Hiraoka Y, Matsuoka T, Ohno M, Nishi K, Sakamoto J, Chen PM, Morita Y, Kita T, Kimura T, Nishi E
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin controls heart rate through the regulation of sinus node automaticity2015
- Author(s)
  Ohno M, Nishi K, Saijo S, Sakamoto J, Chen P-M, Morita Y, Makiyama T, Kita T, Matsuura H, Kimura T, Nishi E.
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PUBLICLY-15H01557
[Presentation] ナルディライジンによる交感神経分布様式と循環動態制御機構2015
- Author(s)
  大野美紀子、平岡義範、西清人、西城さやか、坂本二郎、陳博敏、森田雄介、松田真太郎、北徹、木村剛、西英一郎
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin Controls Heart Rate through the Regulation of Sinus Node Automaticity2015
- Author(s)
  Ohno M, Nishi K, Saijo S, Sakamoto J, Chen PM, Kita T, Morita Y, Hiroshi Matsuura, Kimura T, Nishi E.
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] ナルディライジンによる概日リズム制御機構2015
- Author(s)
  平岡義範、吉種光、布川莉奈、大野美紀子、西清人、森田雄介、久米典昭、北徹、木村剛、深田吉孝、西英一郎
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin controls circulatory dynamics through regulating sympathetic innervation.2015
- Author(s)
  Ohno M, Nishi K, Hiraoka Y, Niizuma S, Saijo S, Sakamoto J, Chen P-M, Morita Y, Matsuda S, Kita T, Kimura T, Nishi E.
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19376
[Presentation] Nardilysin prevents amyloid plaque formation by enhancing α-secretase activity in an Alzheimer's disease mouse model.2015
- Author(s)
  Ohno M, Hiraoka Y, Lichtenthaler SF, Nishi K, Saijo S, Sakamoto J, Chen P-M, Tomimoto H, Araki W, Takahashi R, Kita T, Kimura T, Nishi E
- Organizer
  Brain Protein Aging and Dementia Control, 1st International Symposium
- Place of Presentation
  名古屋大学
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01557
[Presentation] ナルディライジンは急性冠症候群に対する有用なバイオマーカーであり、心筋梗塞後リモデリングを制御する2015
- Author(s)
  陳博敏、大野美紀子、西清人、西城さやか、坂本二郎、森田雄介、松田真太郎、木村剛、西英一郎
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin controls circulatory dynamics through regulating sympathetic innervation.2015
- Author(s)
  Ohno M, Nishi K, Hiraoka Y, Niizuma S, Saijo S, Sakamoto J, Chen P-M, Morita Y, Matsuda S, Kita T, Kimura T, Nishi E.
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PUBLICLY-15H01557
[Presentation] 褐色脂肪組織に発現するナルディライジンは体温恒常性維持機構において重要な役割を示す2015
- Author(s)
  西城さやか、平岡義範、大野美紀子、西清人、坂本二郎、陳博敏、森田雄介、松田真太郎、北徹、木村剛、西英一郎
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin is a Critical Regulator of Pancreatic β-Cell Function2015
- Author(s)
  Nishi K, Sato Y, Ohno M, Saijyo S, Sakamoto J, Chen P, Morita Y, Matsuoka T, Kita T, Inagaki N, Kimura T, Nishi E.
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] The Role of Nardilysin in Cardiac Hypertrophy and Heart Failure2015
- Author(s)
  Sakamoto J, Ohno M, Nishi K, Saijo S, Chen PM, Morita Y, Kita T, Kimura T, Nishi E.
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin controls heart rate through the regulation of sinus node automaticity2015
- Author(s)
  Ohno M, Nishi K, Saijo S, Sakamoto J, Chen P-M, Morita Y, Makiyama T, Kita T, Matsuura H, Kimura T, Nishi E.
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-15K19376
[Presentation] 多機能ペプチダーゼNRDｃの急性冠症候群予知マーカーとしての有用性2015
- Author(s)
  西英一郎、大野美紀子、陳博敏、西清人、西城さやか、坂本二郎、森田雄介、日和佐隆樹、木村剛
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] ナルディライジンはp53活性調節を介して大腸がん細胞HCT116の化学療法感受性を制御する2015
- Author(s)
  坂本二郎、大野美紀子、西清人、西城さやか、陳博敏、森田雄介、松田真太郎、北徹、木村剛、妹尾浩、西英一郎
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Searching for Biomarkers Useful for Acute Coronary Syndrome Prediction by the Screening of Auto-antibodies2015
- Author(s)
  Nishi E, Hiwasa T, Ohno M, Chen PM, Nishi K, Saijo S, Sakamoto J, Morita Y, Kimura T
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] ナルディライジンによる交感神経系を介した循環動態の制御2015
- Author(s)
  大野美紀子、平岡義範、松浦博、西清人、西城さやか、坂本二郎、陳博敏、森田雄介、北徹、木村剛、西英一郎
- Organizer
  第16回日本循環制御医学会
- Place of Presentation
  ウインクあいち
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15K19376
[Presentation] ナルディライジンのゲノム上結合領域および転写制御既往の解明2015
- Author(s)
  森田雄介、大野美紀子、西清人、西城さやか、陳博敏、坂本二郎、松田真太郎、木村剛、西英一郎
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin is Involved in Pressure Overload-induced Dysfunction and Fibrosis of Left Ventricle.2014
- Author(s)
  Sakamoto J, Chen PM, Saijo S, Nishi K, Ohno M, Kita T, Kimura T, Nishi E.
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin is Involved in Pressure Overload-induced Dysfunction and Fibrosis of Left Ventricle2014
- Author(s)
  Sakamoto J, Chen PM, Saijo S, Nishi K, Ohno M, Kita T, Kimura T, Nishi E
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-03-21
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin controls heart rate through regulating sinus node automaticity.2014
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kita T, Kimura T, Nishi E
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PUBLICLY-25113710
[Presentation] 多機能プロテアーゼによる交感神経系を介した循環動態制御機構2014
- Author(s)
  大野美紀子、西清人、西城さやか、坂本二郎、陳博敏、北徹、木村剛、西英一郎
- Organizer
  Molecular Cardiovascular Conference II
- Place of Presentation
  神戸
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin Regulates Adaptive Thermogenesis and Body Temperature Homeostasis through Modulation of PGC-1α2014
- Author(s)
  Saijo S, Hiraoka Y, Matsuoka T, Ohno M, Nakamura K, Matsumura S, Nishi K, Sakamoto J, Chen P, Kita T, Kimura T, Nishi E
- Organizer
  第78回日本循環器学会総会
- Place of Presentation
  東京
- Year and Date
  2014-03-23
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] 多機能プロテアーゼによる交感神経系を介した循環動態調節機構2014
- Author(s)
  大野美紀子、平岡義範、松浦博、西清人、西城さやか、坂本二郎、陳博敏、北徹、木村剛、西英一郎
- Organizer
  第5回Molecular Cardiovascular Conference II
- Place of Presentation
  神戸
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PUBLICLY-25113710
[Presentation] Nardilysin Regulates Adaptive Thermogenesis and Body Temperature Homeostasis through Modulation of PGC-1α2014
- Author(s)
  Saijo S, Hiraoka Y, Matsuoka T, Ohno M, Nakamura K, Matsumura S, Nishi K, Sakamoto J, Chen P, Kita T, Kimura T, Nishi E.
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] ナルディライジンは膵β細胞においてインスリン分泌を制御する2014
- Author(s)
  西清人, 佐藤雄一, 大野美紀子, 平岡義範, 西城さやか, 稲垣暢也, 西英一郎.
- Organizer
  第６１回日本生化学会近畿支部例会
- Place of Presentation
  京都
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] ナルディライジンはPGC-1αを制御することで体温恒常性維持機構と適応熱産生を調節する2014
- Author(s)
  西城さやか，平岡義範, 松岡龍彦, 大野美紀子, 西清人, 西英一郎
- Organizer
  第６１回日本生化学会近畿支部例会
- Place of Presentation
  京都
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin is a critical regulator of glucose-stimulated insulin secretion2014
- Author(s)
  Nishi K, Sato Y, Ohno M, Saijyo S, Sakamoto J, Chen P, Inagaki N, Kimura T, Nishi E.
- Organizer
  Keystone Symposia (Emerging concepts and targets in islet biology)
- Place of Presentation
  Keystone, CO, USA
- Year and Date
  2014-04-08
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardylisin controls glucose metabolism through the regulation of insulin secretion2014
- Author(s)
  Nishi K, Sato Y, Ohno M, Hiraoka Y, Saijyo S, Sakamoto J, Chen P, Kita T, Inagaki N, Kimura T, Nishi E
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-03-21
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin controls heart rate through regulating sinus node automaticity.2014
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kita T, Kimura T, Nishi E.
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PUBLICLY-25122709
[Presentation] ナルディライジンによる心拍数制御機構(学会奨励賞受賞)2013
- Author(s)
  大野美紀子, 平岡義範, 松浦博, 西清人, 西城さやか, 坂本二郎, 陳博敏, 牧山武, 北徹, 木村剛, 西英一郎
- Organizer
  第18回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] ナルディラインジンはグルコース応答性インスリン分泌を制御する2013
- Author(s)
  西清人, 佐藤雄一, 大野美紀子, 平岡義範, 西城さやか, 坂本二郎, 陳博敏, 松岡龍彦, 北徹, 稲垣暢也, 木村剛, 西英一郎
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] ナルディライジンによる心拍数制御機構2013
- Author(s)
  大野美紀子、平岡義範、松浦博、西清人、西城さやか、坂本二郎、陳博敏、牧山武、北徹、木村剛、西英一郎
- Organizer
  第18回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin, an Activator of Ectodomain Shedding, is a Novel and Potent Biomarker for Acute Coronary Syndrome(English session 最優秀賞)2013
- Author(s)
  Ohno M, Watanabe S, Hiraoka Y, Nishi K, Saijo S, Sakamoto J, Chen PM, Kita T, Nishi E, Kimura T
- Organizer
  第115回日本循環器学会近畿地方会
- Place of Presentation
  京都
- Year and Date
  2013-06-15
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] ナルディライジンによる心拍数制御機構2013
- Author(s)
  大野美紀子、平岡義範、松浦博、西清人、西城さやか、坂本二郎、陳博敏、北徹、木村剛、西英一郎
- Organizer
  第18回日本病態プロテアーゼ学
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PUBLICLY-25122709
[Presentation] ナルディライジンによる心拍数制御機構2013
- Author(s)
  大野美紀子、平岡義範、松浦博、西清人、西城さやか、坂本二郎、陳博敏、北徹、木村剛、西英一郎
- Organizer
  第18回日本病態プロテアーゼ学会
- Place of Presentation
  大阪
- Year and Date
  2013-08-16
- Data Source
  KAKENHI-PROJECT-24700366
[Presentation] ナルディライジンはPGC-1αを制御することで体温恒常性維持機構と適応熱産生を調節する2013
- Author(s)
  西城さやか,平岡義範,松岡龍彦,大野美紀子,中村和弘,松村成暢,西清人,坂本二郎,陳博敏, 北徹,木村剛,西英一郎
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardylisin Controls Glucose Metabolism through the Regulation of Insulin Secretion(ポスター)2013
- Author(s)
  Nishi K, Hiraoka Y, Ohno M, Matsuoka T, Saijo S, Sakamoto J, Chen PM, Kita T, Kimura T, Nishi E
- Organizer
  第77回日本循環器学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] ナルディライジンは PGC-1αを制御することで体温恒常性維持機構と適応熱産生を調節する2013
- Author(s)
  西城さやか, 平岡義範, 松岡龍彦, 大野美紀子,中村和弘, 松村成暢, 西清人, 坂本二郎, 陳博敏, 北徹, 木村剛, 西英一郎
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardylisin Controls Glucose Metabolism through the Regulation of Insulin Secretion2013
- Author(s)
  Nishi K, Hiraoka Y, Ohno M, Matsuoka T, Saijo S, Sakamoto J, Chen PM, Kita T, Kimura T, Nishi E.
- Organizer
  第77回日本循環器学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin, an Activator of Ectodomain Shedding, is a Novel and Potent Biomarker for Acute Coronary Syndrome(口頭)2013
- Author(s)
  Ohno M, Watanabe S, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Sakamoto J, Chen PM, Inoue K, Kita T, Kimura T, Nishi E
- Organizer
  第77回日本循環器学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] エネルギー代謝におけるナルディライジンの役割2013
- Author(s)
  大野美紀子、平岡義範、松岡龍彦、西清人、西城さやか、坂本二郎、陳博敏、北徹、木村剛、西英一郎
- Organizer
  動脈硬化若手研究会
- Place of Presentation
  東京
- Year and Date
  2013-10-19
- Data Source
  KAKENHI-PROJECT-24700366
[Presentation] 体温恒常性維持におけるナルディライジンの役割2013
- Author(s)
  西城さやか,平岡義範,松岡龍彦,大野美紀子,中村和弘,松村成暢,西清人,坂本二郎,陳博敏, 北徹,木村剛,西英一郎
- Organizer
  温熱生理研究会
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Critical roles of a metalloendopeptidase nardilysin in cold-induced adaptive thermogenesis2013
- Author(s)
  Hiraoka Y, T. Matsuoka, M. Ohno, K. Nishi, K. Nakamura, K, Kita, T. Kimura and E. Nishi
- Organizer
  ASCB (American Society for Cell Biology)
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] 体温恒常性維持におけるナルディライジンの役割2013
- Author(s)
  西城さやか, 平岡義範, 松岡龍彦, 大野美紀子, 中村和弘, 松村成暢, 西清人, 坂本二郎, 陳博敏, 北徹, 木村剛, 西英一郎
- Organizer
  平成 25年度温熱生理研究会
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] アルツハイマー病におけるナルディライジンの意義2013
- Author(s)
  大野美紀子, 平岡義範, Lichtenthaler Stefan F, 富本秀和, 荒木亙, 高橋良輔, 坂本二郎
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin, an Activator of Ectodomain Shedding, is a Novel and Potent Biomarker for Acute Coronary Syndrome2013
- Author(s)
  Ohno M, Watanabe S, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Sakamoto J, Chen PM, Inoue K, Kita T, Kimura T, Nishi E.
- Organizer
  第77回日本循環器学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin prevents amyloid plaque formation by enhancing alpha-secretase activity in an Alzheimer's disease mouse model2013
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Sakamoto J, Chen PM, Kita T, Kimura T, Nishi E.
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PROJECT-24700366
[Presentation] Nardilysin is a critical regulator of insulin secretion and glucose metabolism2013
- Author(s)
  Nishi K, Sato Y, Ohno M, Hiraoka Y, Saijyo S, Sakamoto J, Chen P, Kita T, Inagaki N, Kimura T, Nishi E.
- Organizer
  American Heart Association scientific sessions 2013
- Place of Presentation
  Dallas, USA
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] ナルディライジンによる交感神経系分布及び循環動態制御機構2013
- Author(s)
  大野美紀子
- Organizer
  第一回京都循環動態研究会
- Place of Presentation
  京都
- Year and Date
  2013-10-18
- Data Source
  KAKENHI-PROJECT-24700366
[Presentation] Nardilysin, an Activator of Ectodomain Shedding, is a Novel and Potent Biomarker for Acute Coronary Syndrome2013
- Author(s)
  Ohno M, Watanabe S, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Sakamoto J, Chen PM, Inoue K, Kita T, Kimura T, Nishi E.
- Organizer
  第回日本循環器学会近畿地方会
- Place of Presentation
  京都
- Year and Date
  2013-06-15
- Data Source
  KAKENHI-PROJECT-24700366
[Presentation] Nardilysin is a critical regulator of insulin secretion and glucose metabolism |2013
- Author(s)
  Nishi K, Sato Y, Ohno M, Hiraoka Y, Saijyo S, Sakamoto J, Chen P, Kita T, Inagaki N, Kimura T, Nishi E
- Organizer
  American Heart Association scientific sessions 2013
- Place of Presentation
  Dallas, USA
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] ナルディライジンはインスリン分泌調節を介して糖代謝を制御する(学会奨励賞受賞)2012
- Author(s)
  西清人, 平岡義範, 大野美紀子, 松岡龍彦, 西城さやか, 坂本二郎, 陳博敏, 北徹, 木村剛, 西英一郎
- Organizer
  第17回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] NRDc regulates circulatory dynamics through modulating sinus node automaticity and cardiac sympathetic innervationポスター発表2012
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kita T, Kimura T, Nishi E
- Organizer
  ESC Congress 2012
- Place of Presentation
  Munich Germany
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] ナルディライジンはインスリン分泌調節を介して糖代謝を制御する2012
- Author(s)
  西清人、平岡義範、大野美紀子、松岡龍彦、西城さやか、坂本二郎、陳博敏、北徹、木村剛、西英一郎
- Organizer
  第17回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin regulates sinus node automaticity and sympathetic nerve innervation2012
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kita T, Kimura T, Nishi E.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] NRDc regulates circulatory dynamics through modulating sinus node automaticity and cardiac sympathetic innervation2012
- Author(s)
  Mikiko Ohno
- Organizer
  European Society of Cardiology 2012
- Place of Presentation
  Munich, Germany
- Year and Date
  2012-08-25
- Data Source
  KAKENHI-PUBLICLY-23122510
[Presentation] Nardylisin controls glucose metabolism through the regulation of insulin secretion2012
- Author(s)
  Nishi K, Hiraoka Y, Ohno M, Matsuoka T, Saijyo S, Sakamoto J, Chen P, Kita T, Kimura T, Nishi E.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] NRDc regulates circulatory dynamics through modulating sinus node automaticity and cardiac sympathetic innervation2012
- Author(s)
  Mikiko Ohno
- Organizer
  International Symposium 2012 Neuro-Vascular Wiring
- Place of Presentation
  Nara- Prefectural New Public Hall, Japan
- Year and Date
  2012-11-12
- Data Source
  KAKENHI-PUBLICLY-23122510
[Presentation] NRDc regulates circulatory dynamics through modulating sinus node automaticity and cardiac sympathetic innervation2012
- Author(s)
  Ohno M, Hiraoka Y, Matsuura H, Matsuoka T, Nishi K, Saijo S, Sakamoto J, Chen PM, Kita T, Kimura T, Nishi E.
- Organizer
  Neuro-Vascular Wiring Symposium 2012
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] NRDc regulates circulatory dynamics through modulating sinus node automaticity and cardiac sympathetic innervation2012
- Author(s)
  Ohno M, Hiraoka Y, Matsuura H, Matsuoka T, Nishi K, Saijo S, Sakamoto J, Chen PM, Kita T, Kimura T, Nishi E
- Organizer
  Neuro-Vascular Wiring Symposium 2012
- Place of Presentation
  Nara
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardylisin controls glucose metabolism through the regulation of insulin secretion2012
- Author(s)
  Nishi K, Hiraoka Y, Ohno M, Matsuoka T, Saijyo S, Sakamoto J, Chen P, Kita T, Kimura T, Nishi E
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] NRDc regulates circulatory dynamics through modulating sinus node automaticity and cardiac sympathetic innervation2012
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kita T, Kimura T, Nishi E.
- Organizer
  European Society of Cardiology, Congress 2012
- Place of Presentation
  Munich- Germany
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin, an activator of ectodomain shedding, is a novel and potent biomarker for acute coronary syndrome2012
- Author(s)
  Ohno M, Watanabe S, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kita T, Nishi E, Kimura T.
- Organizer
  European Society of Cardiology, Congress 2012
- Place of Presentation
  Munich- Germany
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin regulates cardiovascular functions through modulating cardiac sympathetic innervation2012
- Author(s)
  Mikiko Ohno, et.al
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PUBLICLY-23122510
[Presentation] NRDc regulates circulatory dynamics through modulating sinus node automaticity and cardiac sympathetic innervation2012
- Author(s)
  Mikiko Ohno
- Organizer
  European Society of Cardiology 2012
- Place of Presentation
  Munich, Germany
- Data Source
  KAKENHI-PROJECT-24700366
[Presentation] Nardilysin regulates cardiovascular functions through modulating cardiac sympathetic innervation2012
- Author(s)
  大野美紀子, 平岡義範, 松岡龍彦, 西清人, 西城さやか, 北徹, 木村剛, 西英一郎
- Organizer
  第76回日本循環器学会総会
- Place of Presentation
  福岡国際会議場(福岡市)
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin regulates adaptive thermogenesis via modulation of transcriptional coactivator PGC-1α2012
- Author(s)
  Nishi E, Hiraoka Y, Matsuoka T, Ohno M, Nishi K, Saijo S, Kita T, Kimura T
- Organizer
  Cold Spring Harbor Meeting (Nuclear Receptors & Diseases)
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin regulates sinus node automaticity and sympathetic nerve innervation(ワークショップ「発生生物学の最前線 : 個と全体をつなぐ新規メカニズム」 )2012
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kita T, Kimura T, Nishi E
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin regulates adaptive thermogenesis via modulation of transcriptional coactivator PGC-1a (Selected for oral presentation)2012
- Author(s)
  Nishi E, Hiraoka Y, Matsuoka T, Ohno M, Nishi K, Saijo S, Kita T, Kimura T
- Organizer
  Cold Spring Harbor Meeting (Nuclear Receptors & Diseases)
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin regulates circulatory dynamics through modulating sympathetic nerve innervatio2012
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kita T, Kimura T, Nishi E
- Organizer
  第76回日本循環器学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin, an activator of ectodomain shedding, is a novel and potent biomarker for acute coronary syndrome口頭発表2012
- Author(s)
  Ohno M, Watanabe S, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kita T, Nishi E, Kimura T
- Organizer
  ESC Congress 2012
- Place of Presentation
  Munich Germany
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Demyelination and remyelination are distinctly regulated by nardilysin in the murine cuprizone model. Poster presentation2011
- Author(s)
  Ohno M, Nishi E
- Organizer
  10th Biennial ISN Satellite Meeting on Myelin Biology
- Place of Presentation
  Kolymvari, Crete, Grace
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin prevents amyloid plaque formation by enhancing alpha-secretase activity in vivo2011
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijyo S, Kimura T, Nishi E
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin prevents amyloid plaque formation by enhancing alpha-secretase activity in vivo2011
- Author(s)
  Ohno TM, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kimura T, Nishi E
- Organizer
  AAICAD (Alzheimer's Association International Conference on Alzheimer's Disease) 2011
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin prevents amyloid plaque formation by enhancing□□-secretase activity in vivo2011
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kimura T, and Nishi E
- Organizer
  AAICAD (Alzheimer's Association International Conference on Alzheimer's Disease) 2011
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Demyelination and remyelination are distinctly regulated by nardilysin in the murine cuprizone model2011
- Author(s)
  Mikiko Ohno, et.al
- Organizer
  International Society for Neurochemistry, Satellite Meeting on Myelin Biology
- Place of Presentation
  Crete, Greece
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PUBLICLY-23122510
[Presentation] Critical roles of a metalloendopeputidase nardilysin in cold-induced adaptive thermogenesis2011
- Author(s)
  Hiraoka Y, Matsuoka T, Ohno M, Nishi K, Saijyo S, Kimura T, Kita T, Nishi E
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin regulates circulatory dynamics through modulating sympathetic nerve innervation2011
- Author(s)
  Ohno TM, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kimura T, and Nishi E
- Organizer
  The 84th Scientific Sessions of American Heart Association
- Place of Presentation
  Orland, Florida
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin prevents amyloid plaque formation by enhancing alpha-secretase activity in vivo2011
- Author(s)
  Mikiko Ohno, et.al
- Organizer
  Alzheimer's Association International Conference 2011
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PUBLICLY-23122510
[Presentation] Nardilysin Regulates Circulatory Dynamics Through Modulating Sympathetic Nerve Innervation2011
- Author(s)
  Mikiko Ohno, et.al
- Organizer
  American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orlando, USA
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PUBLICLY-23122510
[Presentation] Critical roles of a metalloendopeputidase nardilysin in cold-induced adaptive thermogenesis. 口頭およびポスター発表2011
- Author(s)
  Hiraoka Y, Matsuoka T, Ohno M, Nishi K, Saijo S, Kimura T, Kita T, Nishi E
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] Nardilysin prevents amyloid plaque formation by enhancing □-secretase activity in vivo. 口頭およびポスター発表2011
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Kimura T, Nishi E
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] シェディング活性化因子ナルディライジンの多発性硬化症における意義の解明2010
- Author(s)
  大野美紀子
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22800037
[Presentation] 多機能プロテアーゼによる心拍数制御機構
- Author(s)
  大野美紀子、平岡義範、松浦博、西清人、西城さやか、坂本二郎、陳博敏、牧山武、北徹、木村剛、西英一郎
- Organizer
  第35回日本循環制御医学会総会
- Place of Presentation
  福岡
- Year and Date
  2014-07-04 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] 多機能プロテアーゼによる交感神経系を介した循環動態調節機構
- Author(s)
  大野美紀子、平岡義範、松浦博、西清人、西城さやか、坂本二郎、陳博敏、北徹、木村剛、西英一郎
- Organizer
  第5回Molecular Cardiovascular Conference II
- Place of Presentation
  神戸
- Year and Date
  2014-09-05 – 2014-09-06
- Data Source
  KAKENHI-PUBLICLY-25122709
[Presentation] NRDc regulates circulatory dynamics through modulating cardiac sympathetic innervation.
- Author(s)
  Ohno M, Hiraoka Y, Matsuura H, Matsuoka T, Nishi K, Saijo S, Sakamoto J, Chen PM, Kita T, Kimura T, Nishi E.
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  京都
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PUBLICLY-25122709
[Presentation] Nardilysin prevents amyloid plaque formation by enhancing alpha-secretase activity in an Alzheimer's disease mouse model
- Author(s)
  1. Ohno M, Hiraoka Y, Lichtenthaler S.F, Nishi K, Saijo S, Matsuoka T, Tomimoto H, Araki W, Takahashi R, Kita T, Kimura T and Nishi E.
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24700366
[Presentation] ナルディライジンの心肥大、心不全における役割
- Author(s)
  坂本二郎、大野美紀子、西清人、西城さやか、陳博敏、木村剛、西英一郎
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-08-08 – 2014-08-09
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin, an Activator of Ectodomain Shedding, is a Novel and Potent Biomarker for Acute Coronary Syndrome
- Author(s)
  Ohno M, Watanabe S, Hiraoka Y, Nishi K, Saijo S, Sakamoto J, Chen PM, Kita T, Nishi E, Kimura T.
- Organizer
  第115回日本循環器学会近畿地方会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23300117
[Presentation] 多機能プロテアーゼによる洞房結節自動能制御機構
- Author(s)
  大野美紀子、松浦博、平岡義範、西清人、西城さやか、坂本二郎、陳博俊、牧山武、北徹、木村剛、西英一郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin controls heart rate through the regulation of sinus node automaticity
- Author(s)
  Ohno M, Hiraoka Y, Nishi K, Saijo S, Sakamoto J, Chen P, Makiyama T, Kita T, Matsuura H, Kimura T, Nishi E.
- Organizer
  Cold Spring Harbor Meeting (Nuclear Receptors & Diseases)
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Year and Date
  2014-10-28 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] ナルディライジンによる交感神経系を介した心拍数制御機構
- Author(s)
  大野美紀子、平岡義範、松浦博、西清人、西城さやか、坂本二郎、陳博敏、北徹、木村剛、西英一郎
- Organizer
  日本循環動態医学会
- Place of Presentation
  博多
- Year and Date
  2014-07-04 – 2014-07-05
- Data Source
  KAKENHI-PUBLICLY-25122709
[Presentation] NRDc controls heart rate through regulating sinus node automaticity.
- Author(s)
  Ohno M, Hiraoka Y, Matsuura H, Nishi K, Saijo S, Sakamoto J, Chen PM, Kita T, Kimura T, Nishi E.
- Organizer
  Cold Spring Harbor Laboratory Meeting (Nuclear Receptors & Diseases)
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Year and Date
  2014-10-26 – 2014-11-01
- Data Source
  KAKENHI-PUBLICLY-25122709
[Presentation] NRDc controls heart rate through regulating sinus node automaticity.
- Author(s)
  Ohno M, Hiraoka Y, Matsuura H, Nishi K, Saijo S, Sakamoto J, Chen PM, Kita T, Kimura T, Nishi E
- Organizer
  Cold Spring Harbor Laboratory Meeting
- Place of Presentation
  NY, USA
- Year and Date
  2014-10-26 – 2014-11-01
- Data Source
  KAKENHI-PUBLICLY-25113710
[Presentation] 褐色脂肪組織に発現するナルディライジンは体温恒常性維持機構において重要な役割を示す
- Author(s)
  西城さやか、平岡義範、大野美紀子、中村和弘、松村成暢、西清人、坂本二郎、陳博敏、森田雄介、北徹、木村剛、西英一郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] ナルディライジンはPGC-1αを制御することで体温恒常性維持機構と適応熱産生を調節する
- Author(s)
  西城さやか, 平岡義範, 松岡龍彦, 大野美紀子, 中村和弘, 松村成暢, 西清人, 坂本二郎, 陳博敏, 北徹, 木村剛, 西英一郎
- Organizer
  第46回日本動脈硬化学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Critical role of nardilysin in glucose-stimulated insulin secretion
- Author(s)
  Nishi E, Nishi K, Ohno M, Saijo S, Chen P, Sakamoto J, Kimura T, Kita T.
- Organizer
  Cold Spring Harbor Meeting (Nuclear Receptors & Diseases)
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Year and Date
  2014-10-28 – 2014-11-01
- Invited
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin, an activator of ectodomain shedding, is a novel and potent biomarker for acute coronary syndrome
- Author(s)
  Mikiko Ohno
- Organizer
  第77回　日本循環器学会　学術集会
- Place of Presentation
  横浜,日本
- Data Source
  KAKENHI-PROJECT-24700366
[Presentation] ナルディライジンによるインスリン分泌制御の解析
- Author(s)
  西清人、佐藤雄一、大野美紀子、平岡義範、西城さやか、坂本二郎、陳博敏、森田雄介、松岡龍彦、北徹、稲垣暢也、木村剛、西英一郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] ナルディラインジンはグルコース応答性インスリン分泌を制御する
- Author(s)
  西清人, 佐藤雄一, 大野美紀子, 平岡義範, 西城さやか, 坂本二郎, 陳博敏, 北徹, 稲垣暢也, 木村剛, 西英一郎.
- Organizer
  第46回日本動脈硬化学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-26293068
[Presentation] Nardilysin regulates cardiovascular functions through modulating cardiac sympathetic innervation
- Author(s)
  Ohno M, Hiraoka Y, Matsuoka T, Nishi K, Saijo S, Sakamoto J, Chen PM, Kita T, Kimura T, Nishi E.
- Data Source
  KAKENHI-PROJECT-24700366
[Presentation] ナルディライジンの心肥大、心不全における役割
- Author(s)
  坂本二郎、大野美紀子、西清人、西城さやか、陳博敏、森田雄介、北徹、木村剛、西英一郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293068

1. NISHI Eiichiro (30362528)

# of Collaborated Projects: 9 results

# of Collaborated Products: 169 results
2. 平岡義範 (60397552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 47 results
3. 岩崎広高 (40781589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 西清人 (30749362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 池田真也 (80985804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IWADATE Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 横手幸太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 竹本稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

OHNO MIKIKO 大野 美紀子

OHNO Mikiko 大野 美紀子

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Investigation of proteases with multiple functions as novel therapeutic targets for autoimmune diseases

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多機能プロテアーゼの酵素活性による循環動態制御および心疾患における意義Principal Investigator

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Elucidation of the mechanism by which NRDC, a multifunctional protease, regulates platelet production and its significance as a diagnostic marker for ACS in the hyperacute phase.Principal Investigator

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Investigation of the mechanisms by which Multifaceted Homeostasis is maintained by Nardilysin

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Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticityPrincipal Investigator

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Investigation on the homeostatic regulation by NRDC-p53 axis

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Nardilysin regulates sinus automaticity through transcription of HCN.Principal Investigator

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M16メタロプロテアーゼによる脳タンパク質老化と認知症制御機構Principal Investigator

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Investigation of the multifaceted roles of nardilysin in homeostatic maintenance

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シェディング調節因子による血管収縮と透過性制御機構の解明Principal Investigator

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循環動態調節における交感神経分布様式の意義Principal Investigator

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Nardilysin prevents amyloid plaque formation by enhancing alpha-secretase activity in an Alzheimer's disease mouse model.Principal Investigator

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新規シェディング活性化因子の交感神経―効果器ワイヤリングにおける意義の解明Principal Investigator

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OHNO MIKIKO 大野美紀子

OHNO Mikiko 大野美紀子

[Book] 認知症学会誌　Dementia Japan2016