Onodera Atsushi 小野寺淳

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ONODERA Atsushi 小野寺淳

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Researcher Number	10586598
Other IDs
Affiliation (Current)	2025: 千葉大学, 災害治療学研究所, 教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 千葉大学, 災害治療学研究所, 教授 2016 – 2022: 千葉大学, 大学院医学研究院, 准教授 2020: 千葉大学, 医学(系)研究科(研究院), 准教授 2012 – 2015: 千葉大学, 医学(系)研究科(研究院), 助教 2012: 千葉大学, 大学院・医学研究院, 助教 2011: 千葉大学, 医学(系)研究科(研究院), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / Immunology Except Principal Investigator Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator エピジェネティクス / 発生・分化 / 発現制御 / アレルギー・ぜんそく / 免疫記憶 / 炎症性疾患 / マクロファージ / T細胞 / TET酵素 / 第三世代シークエンス / 抗原応答 / アレルギー･ぜんそく … More Except Principal Investigator … More NKT細胞 / 膠芽腫 / 免疫療法 Less

膠芽腫に対する遺伝子改変iPS細胞由来NKT細胞を用いたがん免疫療法の開発
- Principal Investigator
  
  本橋新一郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Chiba University
DNAメチル化異常による病的炎症発生機構の解明Principal Investigator
- Principal Investigator
  
  小野寺淳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Chiba University
Heterochromatin dysfunction and its related diseases induced by impaired DNA demethylationPrincipal Investigator
- Principal Investigator
  
  ONODERA Atsushi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Chiba University
Active and passive DNA demethylation in T cellsPrincipal Investigator
- Principal Investigator
  
  Onodera Atsushi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Chiba University
Epigenetic regulation of the memory T cell responsePrincipal Investigator
- Principal Investigator
  
  ONODERA Atsushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Chiba University
Polycomb and Trithorax complexes control epigenetic memory of T helper cellsPrincipal Investigator
- Principal Investigator
  
  ONODERA Atsushi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Chiba University
Molecular basis of Polycomb and Trithorax complexes in the maintenance of immunological memoryPrincipal Investigator
- Principal Investigator
  
  ONODERA Atsushi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Chiba University

[Book] 基礎から学ぶ免疫学2023
- Author(s)
  小野寺淳, 小久保幸太, 木内政宏, 岩村千秋, 平原潔, 山下政克 (担当:分担執筆)
- Total Pages
  288
- Publisher
  羊土社
- ISBN
  9784758121682
- Data Source
  KAKENHI-PROJECT-23K24147
[Book] 上田宏の思い出2023
- Author(s)
  小野寺淳, 上田敏 (担当:分担執筆)
- Total Pages
  327
- Publisher
  株式会社シービーアール
- ISBN
  9784911108222
- Data Source
  KAKENHI-PROJECT-23K24147
[Book] エッセンシャル免疫学2023
- Author(s)
  小野寺淳, 中山俊憲 (担当:分担共訳)
- Total Pages
  600
- Publisher
  メディカル・サイエンス・インターナショナル
- ISBN
  9784815730819
- Data Source
  KAKENHI-PROJECT-23K24147
[Book] 免疫生物学原書第9版2019
- Author(s)
  小野寺淳、中山俊憲（第９章担当）、笹月健彦/吉開泰信（監訳）
- Total Pages
  910
- Publisher
  南江堂
- ISBN
  9784524251155
- Data Source
  KAKENHI-PROJECT-18K07164
[Book] Gene Expression and Regulation in Mammalian Cells - Transcription From General Aspects2018
- Author(s)
  Onodera Atsushi、Kokubo Kota、Nakayama Toshinori
- Publisher
  IntechOpen
- ISBN
  9789535138556
- Data Source
  KAKENHI-PROJECT-15K08522
[Book] Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development2014
- Author(s)
  Onodera, A., Tumes, D. J., and Nakayama, T.
- Total Pages
  416
- Publisher
  Springer Berlin Heidelberg
- Data Source
  KAKENHI-PROJECT-25860351
[Journal Article] Anti-Vα24Jα18 TCR Antibody Tunes iNKT Cell Responses to Target and Kill CD1d-negative Tumors in an FcγRII (CD32)-dependent Manner2024
- Author(s)
  Takami Mariko、Aoki Takahiro、Nishimura Katsuhiro、Tanaka Hidekazu、Onodera Atsushi、Motohashi Shinichiro
- Journal Title
  
  Cancer Research Communications
  
  Volume: 4 Issue: 2 Pages: 446-459
- DOI
  10.1158/2767-9764.crc-23-0203
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06690, KAKENHI-PROJECT-23K24147, KAKENHI-PROJECT-23K24441
[Journal Article] Characterization of eosinophils and natural killer cells in nasal polyps and peripheral blood in eosinophilic chronic rhinosinusitis patients2023
- Author(s)
  Tsuji Kaori、Aoki Ami、Onodera Atsushi、Kiuchi Masahiro、Kokubo Kota、Morimoto Yuki、Iinuma Tomohisa、Hanazawa Toyoyuki、Nakayama Toshinori、Hirahara Kiyoshi
- Journal Title
  
  Allergol. Int.
  
  Volume: 72 Issue: 2 Pages: 335-338
- DOI
  10.1016/j.alit.2022.11.009
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15485, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-21K20754, KAKENHI-PROJECT-20KK0351, KAKENHI-PROJECT-23K24147, KAKENHI-PROJECT-22K15484
[Journal Article] Pathogenic helper T cells as the novel therapeutic targets for immune-mediated intractable diseases2023
- Author(s)
  Onodera Atsushi、Kokubo Kota、Okano Mikiko、Onoue Miki、Kiuchi Masahiro、Iwamura Chiaki、Iinuma Tomohisa、Kimura Motoko Y.、Ebihara Nobuyuki、Hanazawa Toyoyuki、Nakayama Toshinori、Hirahara Kiyoshi
- Journal Title
  
  Pharmacology & Therapeutics
  
  Volume: 247 Pages: 108445-108445
- DOI
  10.1016/j.pharmthera.2023.108445
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15485, KAKENHI-PROJECT-22K09739, KAKENHI-PROJECT-22K15484, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-23K24147, KAKENHI-PROJECT-23K27607, KAKENHI-PROJECT-19H05650
[Journal Article] Thioredoxin-interacting protein is essential for memory T cell formation via the regulation of the redox metabolism2023
- Author(s)
  Kokubo Kota、Hirahara Kiyoshi、Kiuchi Masahiro、Tsuji Kaori、Shimada Yuki、Sonobe Yuri、Shinmi Rie、Hishiya Takahisa、Iwamura Chiaki、Onodera Atsushi、Nakayama Toshinori
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 2
- DOI
  10.1073/pnas.2218345120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15484, KAKENHI-PROJECT-22K15485, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-21K20754, KAKENHI-PROJECT-20KK0351, KAKENHI-PROJECT-23K24147, KAKENHI-PROJECT-20K08769
[Journal Article] Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch2023
- Author(s)
  Yuita Hiroshi、Lopez-Moyado Isaac F.、Jeong Hyeongmin、Cheng Arthur Xiuyuan、Scott-Browne James、An Jungeun、Nakayama Toshinori、Onodera Atsushi、Ko Myunggon、Rao Anjana
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120(6) Issue: 6
- DOI
  10.1073/pnas.2214824120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0351, KAKENHI-PROJECT-23K24147, KAKENHI-PROJECT-19H05650
[Journal Article] CD69 Imposes Tumor-Specific CD8+ T-cell Fate in Tumor-Draining Lymph Nodes2023
- Author(s)
  Koyama-Nasu Ryo、Kimura Motoko Y.、Kiuchi Masahiro、Aoki Ami、Wang Yangsong、Mita Yukiyoshi、Hasegawa Ichita、Endo Yukihiro、Onodera Atsushi、Hirahara Kiyoshi、Motohashi Shinichiro、Nakayama Toshinori
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 11 Issue: 8 Pages: 1085-1099
- DOI
  10.1158/2326-6066.cir-22-0406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15485, KAKENHI-PROJECT-23K19462, KAKENHI-PLANNED-22H05189, KAKENHI-PROJECT-23K24147, KAKENHI-PROJECT-23K24441, KAKENHI-PROJECT-19H05650
[Journal Article] Conventional and pathogenic Th2 cells in inflammation, tissue repair, and fibrosis2022
- Author(s)
  Kokubo Kota、Onodera Atsushi、Kiuchi Masahiro、Tsuji Kaori、Hirahara Kiyoshi、Nakayama Toshinori
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 945063-945063
- DOI
  10.3389/fimmu.2022.945063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15484, KAKENHI-PROJECT-22K15485, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-21K20754, KAKENHI-PROJECT-20KK0351, KAKENHI-PROJECT-23K24147
[Journal Article] シングルセル解析2022
- Author(s)
  小野寺淳、本橋新一郎
- Journal Title
  
  耳鼻咽喉科
  
  Volume: 2(5) Pages: 666-667
- Data Source
  KAKENHI-PROJECT-23K24147
[Journal Article] シングルセル解析2022
- Author(s)
  小野寺淳、本橋新一郎
- Journal Title
  
  耳鼻咽喉科
  
  Volume: 2(5) Pages: 666-667
- Data Source
  KAKENHI-PROJECT-20KK0351
[Journal Article] Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis2022
- Author(s)
  Fujimoto Masanori、Yokoyama Masataka、Kiuchi Masahiro、Hosokawa Hiroyuki、Nakayama Akitoshi、Hashimoto Naoko、Sakuma Ikki、Nagano Hidekazu、Yamagata Kazuyuki、Kudo Fujimi、Manabe Ichiro、Lee Eunyoung、Hatano Ryo、Onodera Atsushi、Hirahara Kiyoshi、Yokote Koutaro、Miki Takashi、Nakayama Toshinori、Tanaka Tomoaki
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 1-21
- DOI
  10.1038/s41467-022-33171-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08524, KAKENHI-PROJECT-22K07205, KAKENHI-PROJECT-22K08619, KAKENHI-PROJECT-22K08644, KAKENHI-PROJECT-22K15485, KAKENHI-PROJECT-20KK0373, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-19H03692, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-21H02974, KAKENHI-PROJECT-20K07561, KAKENHI-PROJECT-20K08397, KAKENHI-PROJECT-20K08583, KAKENHI-PROJECT-21K19398, KAKENHI-PROJECT-20KK0351, KAKENHI-PROJECT-23K24062, KAKENHI-PROJECT-23K24147
[Journal Article] The Cxxc1 subunit of the Trithorax complex directs epigenetic licensing of CD4+ T cell differentiation2021
- Author(s)
  Kiuchi Masahiro、Onodera Atsushi、Kokubo Kota、Ichikawa Tomomi、Morimoto Yuki、Kawakami Eiryo、Takayama Naoya、Eto Koji、Koseki Haruhiko、Hirahara Kiyoshi、Nakayama Toshinori
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 218 Issue: 4 Pages: 3-8
- DOI
  10.1084/jem.20201690
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-19K16683, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-18K07164, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-21K20754
[Journal Article] CD4+ T cells in inflammatory diseases: pathogenic T-helper cells and the CD69-Myl9 system2021
- Author(s)
  Nakayama Toshinori、Hirahara Kiyoshi、Kimura Motoko Y、Iwamura Chiaki、Kiuchi Masahiro、Kokubo Kota、Onodera Atsushi、Hashimoto Kahoko、Motohashi Shinichiro
- Journal Title
  
  International Immunology
  
  Volume: 33(12) Issue: 12 Pages: 699-704
- DOI
  10.1093/intimm/dxab053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-20K21537, KAKENHI-PROJECT-19K16683, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-20K08769, KAKENHI-PROJECT-21K20754, KAKENHI-PROJECT-20KK0351
[Journal Article] Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells2021
- Author(s)
  Onodera Atsushi、Gonzalez-Avalos Edahi、Lio Chan-Wang Jerry、Georges Romain O.、Bellacosa Alfonso、Nakayama Toshinori、Rao Anjana
- Journal Title
  
  Genome Biology
  
  Volume: 22(1) Issue: 1 Pages: 186-186
- DOI
  10.1186/s13059-021-02384-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20KK0351
[Journal Article] Epigenetic regulation of inflammation by CxxC domain‐containing proteins2021
- Author(s)
  Onodera Atsushi、Kiuchi Masahiro、Kokubo Kota、Nakayama Toshinori
- Journal Title
  
  Immunological Reviews
  
  Volume: 305(1) Issue: 1 Pages: 137-151
- DOI
  10.1111/imr.13056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-19K16683, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-21K20754, KAKENHI-PROJECT-20KK0351
[Journal Article] CxxCドメインを持つタンパク質によるT細胞および炎症の制御2021
- Author(s)
  小野寺淳、木内政宏、中山俊憲
- Journal Title
  
  アレルギーの臨床
  
  Volume: 41(10) Pages: 897-901
- Data Source
  KAKENHI-PROJECT-20KK0351
[Journal Article] Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation2020
- Author(s)
  Suzuki Akane S.、Yagi Ryoji、Kimura Motoko Y.、Iwamura Chiaki、Shinoda Kenta、Onodera Atsushi、Hirahara Kiyoshi、Tumes Damon J.、Koyama-Nasu Ryo、Iismaa Siiri E.、Graham Robert M.、Motohashi Shinichiro、Nakayama Toshinori
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 1536-1536
- DOI
  10.3389/fimmu.2020.01536
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08769, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-20K21537, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-18H02892, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-18K07164, KAKENHI-PROJECT-18K07257, KAKENHI-PROJECT-19K23838
[Journal Article] エフェクター、メモリーTh2細胞の誘導と維持のエピジェネティクス2019
- Author(s)
  小久保幸太、小野寺淳、中山俊憲
- Journal Title
  
  臨床免疫／アレルギー科
  
  Volume: 72(2) Pages: 117-122
- Data Source
  KAKENHI-PROJECT-18K07164
[Journal Article] ACC1 determines memory potential of individual CD4+ T cells by regulating de novo fatty acid biosynthesis2019
- Author(s)
  Yusuke Endo, Atsushi Onodera, Kazushige Obata-Ninomiya, Ryo Koyama-Nasu, Hikari K. Asou, Toshihiro Ito, Takeshi Yamamoto, Toshio Kanno, Takahiro Nakajima, Kenji Ishiwata, Hirotaka Kanuka, Damon J. Tumes, Toshinori Nakayama
- Journal Title
  
  Nature Metabolism
  
  Volume: 1(2) Issue: 2 Pages: 261-275
- DOI
  10.1038/s42255-018-0025-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07164, KAKENHI-PUBLICLY-18H04665, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-18K07257
[Journal Article] TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion2019
- Author(s)
  Seo H, Chen J, Gonzalez-Avalos E, Samaniego-Castruita D, Das A, Wang YH, Lopez-Moyado IF, Georges RO, Zhang W, Onodera A, Wu CJ, Lu LF, Hogan PG, Bhandoola A, Rao A.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 25 Pages: 12410-12415
- DOI
  10.1073/pnas.1905675116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07164
[Journal Article] CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells2019
- Author(s)
  Ichikawa, T.*, Hirahara, K.*, Kokubo, K.*, Kiuchi, M., Aoki, A., Morimoto, Y., Kumagai, J., Onodera, A., Mato, N., Tumes, D., Goto, Y., Hagiwara, K., Inagaki, Y., Sparwasser, T., Tobe, K., and Nakayama, T.
- Journal Title
  
  Nature Immunology
  
  Volume: 20 Issue: 11 Pages: 1469-1480
- DOI
  10.1038/s41590-019-0494-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07164, KAKENHI-PROJECT-19K22627, KAKENHI-PROJECT-19K16683, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-19H03465, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-17K08876
[Journal Article] Ezh2 controls development of natural killer T cells, which cause spontaneous asthma-like pathology2019
- Author(s)
  Tumes, D., Hirahara, K., Papadopoulos, M., Shinoda, K., Onodera, A., Kumagai, J., Yip, KH., Pant, H., Kokubo, K., Masahiro, K., Aoki, A., Obata-Ninomiya, K., Yokoyoda, K., Endo, Y., Kimura, MY., Nakayama, T.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 0091-6749(19) Issue: 2 Pages: 30340-9
- DOI
  10.1016/j.jaci.2019.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-18K07164, KAKENHI-PROJECT-18K19466, KAKENHI-PUBLICLY-17H05787, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-20K20383, KAKENHI-PUBLICLY-18H04665, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650
[Journal Article] Role of leukotriene B4 12-hydroxydehydrogenase in α-galactosylceramide-pulsed dendritic cell therapy for non-small cell lung cancer2018
- Author(s)
  Tanaka K, Kanesaka Y, Takami M, Suzuki A, Hosokawa H, Onodera A, Kamata T, Nagato K, Nakayama T, Yoshino I, Motohashi S
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 506(1) Issue: 1 Pages: 27-32
- DOI
  10.1016/j.bbrc.2018.10.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07164, KAKENHI-PROJECT-18K16409, KAKENHI-PROJECT-18H02892
[Journal Article] DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells2018
- Author(s)
  Yamamoto, T., Endo, Y., Onodera, A., Hirahara, K., Asou, H., Nakajima, T., Kanno, T., Ouchi, Y., Uematsu, S., Nishimasu, H., Nureki, O., Tumes, D. J., Shimojo, N., and Nakayama, T.
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 4231-4231
- DOI
  10.1038/s41467-018-06468-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-18K07164, KAKENHI-PUBLICLY-18H04665, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-17H04257, KAKENHI-PROJECT-18H02571, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-17K19543, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-17K07212, KAKENHI-PROJECT-17KK0189
[Journal Article] Amphiregulin-Producing Pathogenic Memory T Helper 2 Cells Instruct Eosinophils to Secrete Osteopontin and Facilitate Airway Fibrosis2018
- Author(s)
  Morimoto, Y., Hirahara, K., Kiuchi, M., Wada, T., Ichikawa, T., Kanno, T., Okano, M., Kokubo, K., Onodera, A., Sakurai, D., Okamoto, Y., Nakayama, T.
- Journal Title
  
  Immunity
  
  Volume: 49 Issue: 1 Pages: 134-150
- DOI
  10.1016/j.immuni.2018.04.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-18K07164, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-18K16830, KAKENHI-PROJECT-20K20383
[Journal Article] CXCR6+ST2+ memory T helper 2 cells induced the expression of major basic protein in eosinophils to reduce the fecundity of helminth2018
- Author(s)
  Obata-Ninomiya, K., Ishiwata, K., Nakano, H., Endo, Y., Ichikawa, T., Onodera, A., Hirahara, K., Okamoto, Y., Kanuka, H., Nakayama, T.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 42
- DOI
  10.1073/pnas.1714731115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-18K07164, KAKENHI-PUBLICLY-18H04665, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-20K20383
[Journal Article] Epigenetic and Transcriptional Regulation in the Induction, Maintenance, Heterogeneity, and Recall-Response of Effector and Memory Th2 Cells2018
- Author(s)
  Onodera A, Kokubo K, Nakayama T
- Journal Title
  
  Front Immunol.
  
  Volume: 9 Pages: 2929-2929
- DOI
  10.3389/fimmu.2018.02929
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07164, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-20K20383
[Journal Article] Anti-tumor immunity via the superoxide-eosinophil axis induced by a lipophilic component of Mycobacterium lipomannan2017
- Author(s)
  Ito Toshihiro、Hirahara Kiyoshi、Onodera Atsushi、Koyama-Nasu Ryo、Yano Ikuya、Nakayama Toshinori
- Journal Title
  
  Int. Immunol
  
  Volume: 29 Issue: 9 Pages: 411-421
- DOI
  10.1093/intimm/dxx051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-15K06838, KAKENHI-PROJECT-15K08522
[Journal Article] Menin Controls the Memory Th2 Cell Function by Maintaining the Epigenetic Integrity of Th2 Cells2017
- Author(s)
  Onodera Atsushi、Kiuchi Masahiro、Kokubo Kota、Kato Miki、Ogino Tomohiro、Horiuchi Shu、Kanai Urara、Hirahara Kiyoshi、Nakayama Toshinori
- Journal Title
  
  J Immunol
  
  Volume: 199 Issue: 3 Pages: 1153-1162
- DOI
  10.4049/jimmunol.1602129
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-15K08522
[Journal Article] Epigenetic regulation of T-helper cell differentiation, memory, and plasticity in allergic asthma2017
- Author(s)
  Tumes Damon J.、Papadopoulos Magdalene、Endo Yusuke、Onodera Atsushi、Hirahara Kiyoshi、Nakayama Toshinori
- Journal Title
  
  Immunol. Rev
  
  Volume: 278 Issue: 1 Pages: 8-19
- DOI
  10.1111/imr.12560
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PUBLICLY-16H01352, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-15K08522
[Journal Article] The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells2017
- Author(s)
  Iwata Shigeru、Mikami Yohei、Sun Hong-Wei、Brooks Stephen R.、Jankovic Dragana、Hirahara Kiyoshi、Onodera Atsushi、Shih Han-Yu、Kawabe Takeshi、Jiang Kan、Nakayama Toshinori、Sher Alan、O’Shea John J.、Davis Fred P.、Kanno Yuka
- Journal Title
  
  Immunity
  
  Volume: 46 Issue: 6 Pages: 983-991.e4
- DOI
  10.1016/j.immuni.2017.05.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-15K08522
[Journal Article] Myosin light chain 9 and 12 are functional ligands for CD69 that regulate airway inflammation2016
- Author(s)
  Hayashizaki, K., Kimura, M. Y., Tokoyoda, K., Hosokawa, H., Shinoda, K., Hirahara, K., Ichikawa, T., Onodera, A., Hanazawa, A., Iwamura, C., Kakuta, J., Muramoto, K., Motohashi, S., Tumes, D. J., Iinuma, T., Yamamoto, H., Ikehara, Y., Okamoto, Y., and Nakayama, T.
- Journal Title
  
  Sci. Immunol.
  
  Volume: 1 Issue: 3
- DOI
  10.1126/sciimmunol.aaf9154
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-15K08522, KAKENHI-PROJECT-15K08524
[Journal Article] Th2 cells in health and disease.2016
- Author(s)
  Nakayama T, Hirahara K, Onodera A, Endo Y, Hosokawa H, Shinoda K, Tumes DJ, Okamoto Y.
- Journal Title
  
  Annu Rev Immunol.
  
  Volume: 35 Issue: 1 Pages: 53-84
- DOI
  10.1146/annurev-immunol-051116-052350
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05483, KAKENHI-PROJECT-17K08876, KAKENHI-PUBLICLY-16H01352, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-15K08522
[Journal Article] ヘルパーT細胞分化とエピジェネティクス2015
- Author(s)
  小野寺淳、中山俊憲
- Journal Title
  
  炎症と免疫
  
  Volume: 23 Pages: 199-205
- Data Source
  KAKENHI-PROJECT-15K08522
[Journal Article] Asymmetric action of STAT transcription factors drives transcriptional outputs and cytokine specificity.2015
- Author(s)
  Hirahara, K., Onodera, A., Villario, A. V., Bonelli, M., Sciume, G., Laurence, A., Sun, H. W., Brooks, S. R., Vahedi, G., Shih, H. Y., Gtierrez-Cruz, G., Iwata, S., Suzuki, R., Mikami, Y., Okamoto, Y., Nakayama, T., Holland, S. M., Hunter, C. A., Kanno, Y., and O’Shea, J. J.
- Journal Title
  
  Immunity
  
  Volume: 42 Issue: 5 Pages: 877-889
- DOI
  10.1016/j.immuni.2015.04.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08522, KAKENHI-PROJECT-15K14495
[Journal Article] Epigenetics of T cells regulated by Polycomb/Trithorax molecules.2015
- Author(s)
  Onodera, A., and Nakayama, T.
- Journal Title
  
  Trends Mol. Med.
  
  Volume: - Issue: 5 Pages: 1-11
- DOI
  10.1016/j.molmed.2015.03.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860351, KAKENHI-PROJECT-26221305
[Journal Article] Spatial interplay between Polycomb and Trithorax complexes controls transcriptional activity in T lymphocytes.2015
- Author(s)
  Onodera, A., Tumes, D. J., Watanabe, Y., Hirahara, K., Kaneda, A., Sugiyama, F., Suzuki, Y., and Nakayama, T.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 35 Issue: 22 Pages: 3841-3853
- DOI
  10.1128/mcb.00677-15
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08522, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-26670595
[Journal Article] Sox5 and c-Maf cooperatively induce Th17 cell differentiation via ROR gamma t induction as downstream targets of Stat32014
- Author(s)
  Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami S, Suzuki K, Takatori H, Tamachi T, Hirose K, Onodera A, Suzuki J, Ohara O, Yamashita M, Nakayama T, Nakajima H
- Journal Title
  
  J Exp Med
  
  Volume: 211 Issue: 9 Pages: 1857-1874
- DOI
  10.1084/jem.20130791
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390207, KAKENHI-PROJECT-25461492, KAKENHI-PROJECT-25860351, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-26461184, KAKENHI-PROJECT-26461460, KAKENHI-PROJECT-26461461, KAKENHI-PROJECT-26461486
[Journal Article] Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development.2014
- Author(s)
  Mishima Y, Wang C, Miyagi S, Saraya A, Hosokawa H, Mochizuki-Kashio M, Nakajima-Takagi Y, Koide S, Negishi M, Sashida G, Naito T, Ishikura T, Onodera A, Nakayama T, Tenen DG, Yamaguchi N, Koseki H, Taniuchi I, Iwama A.
- Journal Title
  
  Nature Communications
  
  Volume: 18 Issue: 1 Pages: 5872-5882
- DOI
  10.1038/ncomms6872
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J40042, KAKENHI-PROJECT-24249054, KAKENHI-PROJECT-25460599, KAKENHI-PROJECT-25860351, KAKENHI-PUBLICLY-26114720, KAKENHI-PLANNED-26115002, KAKENHI-PROJECT-26293109, KAKENHI-PROJECT-26460569, KAKENHI-PROJECT-26461396
[Journal Article] Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.2014
- Author(s)
  Watanabe, Y., Onodera, A., Kanai, U., Ichikawa, T., Obata-Ninomiya, K., Wada, T., Kiuchi, M., Iwamura, C., Tumes, DJ., Shinoda, K., Yagi, R., Motohashi, S., Hirahara, K. and Nakayama, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 111(35) Issue: 35 Pages: 12829-34
- DOI
  10.1073/pnas.1321245111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-25860351, KAKENHI-PROJECT-25860352, KAKENHI-PROJECT-25893032, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-26870172
[Journal Article] Th2特異的遺伝子のGATA3依存的，非依存的な発現制御機構2013
- Author(s)
  堀内周、小野寺淳、中山俊憲
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 59 Pages: 25-33
- Data Source
  KAKENHI-PROJECT-23790523
[Journal Article] Th2特異的遺伝子のGATA3依存的2013
- Author(s)
  堀内周、小野寺淳、中山俊憲
- Journal Title
  
  非依存的な発現制御機構臨床免疫・アレルギー科(科学評論社)
  
  Volume: 59(1) Pages: 25-33
- Data Source
  KAKENHI-PROJECT-23790523
[Journal Article] Genomic-wide gene expression profiling revealed a critical role for GATA3 in the maintenance of the Th2 cell identity.2013
- Author(s)
  Sasaki, T., Onodera, A., Hosokawa, H., Watanabe, Y., Horiuchi, S., Yamashita, J., Tanaka, H., Ogawa, Y., Suzuki, Y., and Nakayama, T.
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 6 Pages: e66468-e66468
- DOI
  10.1371/journal.pone.0066468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860351
[Journal Article] The polycomb protein Ezh2 regulates differentiation and plasticity of CD4+ T helper type-1 and type-2 cells.2013
- Author(s)
  Tumes, D. J., Onodera, A., Suzuki, A., Shinoda, K., Endo, Y., Iwamura, C., Hosokawa, H., Koseki, H., Tokoyoda, K., Suzuki, Y., Motohashi, S., and Nakayama, T.
- Journal Title
  
  Immunity
  
  Volume: 39 Issue: 5 Pages: 819-32
- DOI
  10.1016/j.immuni.2013.09.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592083, KAKENHI-PROJECT-24790460, KAKENHI-PROJECT-24790461, KAKENHI-PROJECT-25860351, KAKENHI-PROJECT-25860352
[Journal Article] Too much of a good thing.2013
- Author(s)
  Onodera, A., Tumes, D. J., and Nakayama, T.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 14 Issue: 2 Pages: 112-114
- DOI
  10.1038/ni.2510
- Data Source
  KAKENHI-PROJECT-23790523
[Journal Article] Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity.2013
- Author(s)
  Hosokawa H
- Journal Title
  
  Proc Natl Acad Sci U SA
  
  Volume: - Issue: 12 Pages: 4691-4696
- DOI
  10.1073/pnas.1220865110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300325, KAKENHI-PROJECT-22591093, KAKENHI-PROJECT-23659240, KAKENHI-PROJECT-23790523, KAKENHI-PUBLICLY-24116506, KAKENHI-PROJECT-24390239, KAKENHI-PROJECT-24790461, KAKENHI-PROJECT-25670438, KAKENHI-PROJECT-221S0002
[Journal Article] 中山俊憲STAT6依存的および非依存的なGata3の発現制御機構-Gata3発現はSTAT6によって誘導され2012
- Author(s)
  小野寺淳
- Journal Title
  
  Menin/TrxG複合体によって維持される-臨床免疫・アレルギ-科
  
  Volume: 57(3) Pages: 330-341
- Data Source
  KAKENHI-PROJECT-23790523
[Journal Article] The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-・ and suppresses TH2 differentiation2012
- Author(s)
  Kuwahara, M., Yamashita, M., Shinoda, K., Tofukuji, S., Onodera, A., Shinnakasu, R., Motohashi, S., Hosokawa, H., Tumes, D., Iwamura, C., Lefebvre, V., and Nakayama, T.
- Journal Title
  
  Nat. Immunol
  
  Volume: 13(8) Issue: 8 Pages: 778-786
- DOI
  10.1038/ni.2362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591093, KAKENHI-PROJECT-23390075, KAKENHI-PROJECT-23592624, KAKENHI-PROJECT-23659240, KAKENHI-PROJECT-23790522, KAKENHI-PROJECT-23790523, KAKENHI-PROJECT-23890030, KAKENHI-PROJECT-24592083, KAKENHI-PROJECT-24790459
[Journal Article] Memory type 2 helper T cells induce long-lasting anti-tumor immunity by activating natural killer cells. 71:4790-4798 (2011).2011
- Author(s)
  Kitajima, M., Ito, T., Tumes, J. D., Endo, Y., Onodera, A., Hashimoto, K., Motohashi, S., Yamashita, M., Nishimura, T., Ziegler, F. S. and Nakayama, T.
- Journal Title
  
  Cancer Res.
  
  Volume: 71 Pages: 4790-4798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790523
[Journal Article] Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA32011
- Author(s)
  Horiuchi, S., Onodera, A., Hosokawa, H., Watanabe, Y., Tanaka, T., Sugano, S., SuzukiY. Nakayama, T
- Journal Title
  
  J. Immunol
  
  Volume: 186 Issue: 11 Pages: 6378-6389
- DOI
  10.4049/jimmunol.1100179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390147, KAKENHI-PROJECT-22591093, KAKENHI-PROJECT-23659240, KAKENHI-PROJECT-23790522, KAKENHI-PROJECT-23790523, KAKENHI-PROJECT-221S0002
[Journal Article] T細胞機能分化のエピジェネティクス2011
- Author(s)
  小野寺淳、中山俊憲
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 41(2) Pages: 22-31
- Data Source
  KAKENHI-PROJECT-23790523
[Journal Article] ポリコームとトライソラックスによるGata3遺伝子発現のエピジェネティック制御2011
- Author(s)
  小野寺淳
- Journal Title
  
  医学のあゆみ
  
  Volume: 237(13) Pages: 1154-1160
- Data Source
  KAKENHI-PROJECT-23790523
[Journal Article] Gata3遺伝子のエピジェネティック制御2011
- Author(s)
  小野寺淳
- Journal Title
  
  医学のあゆみ
  
  Volume: 237(4) Pages: 314-314
- Data Source
  KAKENHI-PROJECT-23790523
[Journal Article] 中山俊憲CD4免疫記憶と機能維持-エピジェネティック研究から得られた新知見2011
- Author(s)
  小野寺淳、堀内周
- Journal Title
  
  実験医学増刊免疫学のブラックボックス免疫記憶の制御と疾患治療
  
  Volume: 29(17) Pages: 20-28
- Data Source
  KAKENHI-PROJECT-23790523
[Journal Article] Memory type 2 helper T cells induce long-lasting anti-tumor immunityby activating natural killer cells2011
- Author(s)
  Kitajima, M., Ito, T., Tumes, J. D., Endo, Y., Onodera, A., Hashimoto, K., Motohashi, S., Yamashita, M., Nishimura, T., Ziegler, F. S. Nakayama, T
- Journal Title
  
  Cancer Res
  
  Volume: 71 Issue: 14 Pages: 4790-4798
- DOI
  10.1158/0008-5472.can-10-1572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390147, KAKENHI-PROJECT-22300331, KAKENHI-PROJECT-22591093, KAKENHI-PROJECT-23659240, KAKENHI-PROJECT-23790523
[Presentation] Lipolysis-microlipophagy cascade regulated by adipose triglyceride lipase drives pathogenic type 2 adaptive immunity via the PPARg-ST2 axis2024
- Author(s)
  Hiroyuki Yagyu, Masahiro Kiuchi, Kota Kokubo, Atsushi Sasaki, Atsushi Onodera, Chiaki Iwamura, Takeshi Kaneko, Toshinori Nakayama, Kiyoshi Hirahara
- Organizer
  Dr. Toshinori Nakayama Memorial cMAV-cSIMVa Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] Suppression of type I interferon signaling in myeloid cells by autoantibodies in severe COVID-19 patients2024
- Author(s)
  Atsushi Sasaki, Ami Aoki, Chiaki Iwamura, Masahiro Kiuchi, Kaori Tsuji, Takahisa Hishiya, Rui Hirasawa, Kota Kokubo, Atsushi Onodera, Takuji Suzuki, Toshinori Nakayama, Kiyoshi Hirahara
- Organizer
  第52回日本免疫学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] DNA demethylation in the immune system: do TET and TDG play roles?2024
- Author(s)
  Atsushi Onodera
- Organizer
  Dr. Toshinori Nakayama Memorial cMAV-cSIMVa Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] Characterization of eosinophils and natural killer cells in nasal polyps and peripheral blood in eosinophilic chronic rhinosinusitis patients2024
- Author(s)
  Kaori Tsuji, Ami Aoki, Atsushi Onodera, Masahiro Kiuchi, Kota Kokubo, Yuki Morimoto, Tomohisa Iinuma, Toyoyuki Hanazawa, Toshinori Nakayama, Kiyoshi Hirahara
- Organizer
  第52回日本免疫学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] Overview Talk: Epigenetic regulation in health and disease2024
- Author(s)
  Atsushi Onodera
- Organizer
  第52回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] Thioredoxin-interacting protein is essential for memory T cell formation via the regulation of the redox metabolism2024
- Author(s)
  Kota Kokubo, Kiyoshi Hirahara, Masahiro Kiuchi, Kaori Tsuji, Yuri Sonobe, Rie Shinmi, Takahisa Hishiya, Chiaki Iwamura, Atsushi Onodera, Toshinori Nakayama
- Organizer
  第52回日本免疫学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] CD69 regulates anti-tumor CD8T cell responses.2023
- Author(s)
  Nasu, R., Wang, YS., Endo, Y., Hasegawa, I., Mita, Y., Onodera, A., Motohashi, S., Nakayama T., and Kimura KY.
- Organizer
  International Symposium for Future Mucosal Vaccines: Safeguards and Innovations against Infectious Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0351
[Presentation] Roles of TET and TDG in DNA demethylation in the immune system2023
- Author(s)
  Onodera, A., Tanaka, H., Hirahara, K., Nakayama, T., and Rao, A.
- Organizer
  International Symposium for Future Mucosal Vaccines: Safeguards and Innovations against Infectious Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] Unsaturated fatty acids promote pathogenic type 2 adaptive immunity via PPARg-ST2 axis. International Symposium for Future Mucosal Vaccines2023
- Author(s)
  Yagyu, H., Kiuchi, M., Kokubo, K., Sasaki, A., Onodera, A., Iwamura, C., Kaneko, T., Nakayama T., and Hirahara, K.
- Organizer
  Safeguards and Innovations against Infectious Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0351
[Presentation] CD69 regulates anti-tumor CD8T cell responses2023
- Author(s)
  Nasu, R., Wang, YS., Endo, Y., Hasegawa, I., Mita, Y., Onodera, A., Motohashi, S., Nakayama T., and Kimura KY.
- Organizer
  International Symposium for Future Mucosal Vaccines: Safeguards and Innovations against Infectious Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] TETとTDGによるDNAシトシン脱メチル化反応と免疫・血液疾患2023
- Author(s)
  小野寺淳, 田中秀和, 平原潔, 中山俊憲, Anjana Rao
- Organizer
  第16回日本エピジェネティクス研究会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] Roles of TET and TDG in DNA demethylation in the immune system. International Symposium for Future Mucosal Vaccines2023
- Author(s)
  Onodera, A., Tanaka, H., Hirahara, K., Nakayama, T., and Rao, A.
- Organizer
  Safeguards and Innovations against Infectious Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0351
[Presentation] Unsaturated fatty acids promote pathogenic type 2 adaptive immunity via PPARg-ST2 axis2023
- Author(s)
  Yagyu, H., Kiuchi, M., Kokubo, K., Sasaki, A., Onodera, A., Iwamura, C., Kaneko, T., Nakayama T., and Hirahara, K.
- Organizer
  International Symposium for Future Mucosal Vaccines: Safeguards and Innovations against Infectious Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] Nematode ascarosides attenuate mammalian type 2 inflammatory responses.2022
- Author(s)
  Kiuchi, M., Kokubo, K., Onodera, A., Hirahara, K., and Nakayama, T.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20KK0351
[Presentation] Connecting TET2 deficiency with inflammation in CMML and anti-tumor responses.2022
- Author(s)
  Singh, AK., Onodera, A., Lopez-Moyado, IF., Sepulveda, H., Angel, JC., Rao, A.
- Organizer
  AACR, New Orleans, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0351
[Presentation] Connecting TET2 deficiency with inflammation in CMML and anti-tumor responses.2022
- Author(s)
  Singh, AK., Onodera, A., Lopez-Moyado, IF., Sepulveda, H., Angel, JC., Rao, A.
- Organizer
  AACR, New Orleans, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] Nematode ascarosides attenuate mammalian type 2 inflammatory responses.2022
- Author(s)
  Kiuchi, M., Kokubo, K., Onodera, A., Hirahara, K., and Nakayama, T.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24147
[Presentation] The Cxxc1 subunit of the Trithorax complex directs epigenetic licensing of CD4+ T cell differentiation2021
- Author(s)
  Masahiro Kiuchi., Atsushi Onodera., Kota Kokubo., Eiryo Kawakami., Haruhiko Koseki., Kiyoshi Hirahara., Toshinori Nakayama
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20KK0351
[Presentation] Trithorax Cxxc1-directed epigenetic machinery licensing CD4+ T cell differentiation2021
- Author(s)
  Masahiro Kiuchi., Atsushi Onodera., Kota Kokubo., Tomomi Ichikawa., Eiryo Kawakami., Naoya Takayama., Koji Eto., Haruhiko Koseki., Kiyoshi Hirahara., Toshinori Nakayama
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-20KK0351
[Presentation] アレルギー炎症に伴う線維化に対する新規治療法開発2020
- Author(s)
  平原潔、小野寺淳、飯沼智久、間藤尚子
- Organizer
  難治性疾患実用化研究事業免疫アレルギー疾患実用化研究事業 2019年度合同成果報告会
- Data Source
  KAKENHI-PROJECT-18K07164
[Presentation] Spatial interplay between Polycomb and Trithorax complexes controls transcriptional activity in T lymphocytes.2016
- Author(s)
  Onodera, A., Tumes, D.J., Kiuchi, M., Kokubo, K., Watanabe, Y., Hirahara, K., Kaneda, A., Sugiyama, F., Suzuki, Y., and Nakayama, T.
- Organizer
  International Congress of Immunology 2016
- Place of Presentation
  MELBOURNE, AUSTRALIA
- Year and Date
  2016-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08522
[Presentation] A quantitative method for evaluating binding positions of Trithorax and Polycomb proteins based on correlation function or entropy.2016
- Author(s)
  Onodera, A., Ogino, T., Kiuchi, M., Kokubo, K., and Nakayama, T.
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-15K08522
[Presentation] POLYCOMB AND TRITHORAX COMPLEXES CONTROL EPIGENETIC MEMORY OF T HELPER CELLS.2015
- Author(s)
  Onodera A, Hirahara K and Nakayama T.
- Organizer
  NCI Symposium on Chromosome Biology
- Place of Presentation
  Bethesda, MD, USA
- Year and Date
  2015-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08522
[Presentation] Fine scale positioning of Polycomb and Trithorax complexes controls transcriptional activity in T lymphocytes.2015
- Author(s)
  Onodera, A., Kiuchi, M., Wada, T., Kanno, T., Hayashizaki, K., and Nakayama, T.
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K08522
[Presentation] ポリコーム／トライソラックス複合体による免疫細胞記憶維持機構の解明2015
- Author(s)
  Onodera, A., and Nakayama, T.
- Organizer
  第25回Kyoto T Cell Conference
- Place of Presentation
  京都大学芝蘭会館(京都府・京都市)
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-15K08522
[Presentation] Epigenetic regulation of helper T cells by Polycomb and Trithorax complexes2013
- Author(s)
  Onodera, A., Horiuchi, S., Sasaki, T., Hosokawa, H., Watanabe, Y., Suzuki, Y., and Nakayama, T.
- Organizer
  International Symposium on Genome Science
- Place of Presentation
  Tokyo
- Year and Date
  2013-01-09
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Regulation of memory CD4 T cell pool size and function by NKT cells invivo2012
- Author(s)
  Iwamura, C., Endo, Y., Onodera, A.,Watanabe, Y., Suzuki, A., Kinjo, Y., and Nakayama, T.
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-06
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Genome-wide gene expression profiling revealed a critical role for GATA3 in the maintenance of the Th2 cell phenotype2012
- Author(s)
  Sasaki, T., Onodera, A., Hosokawa, H., Watanabe, Y., Horiuchi, S., Yamashita, J., and Nakayama, T.
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Regulation of memory Th2 cell function and allergic airway inflammation via polycomb and trithorax molecules.2011
- Author(s)
  Nakayama, T., and Onodera, A.
- Organizer
  30th Congress of the European Academy of Allergy and Clinical Immunology
- Place of Presentation
  Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Epigenetic control of memory Th2 cell function via Polycomb and Trithorax molecules.2011
- Author(s)
  Nakayama, T., and Onodera, A.
- Organizer
  EUThyme-Rolduc Meeting
- Place of Presentation
  Leeuwenhorst, NL
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3.2011
- Author(s)
  Onodera, A., Horiuchi, S., Hosokawa, H., Watanabe, Y., Suzuki, Y., and Nakayama, T..
- Organizer
  NCI Symposium on Chromosome Structure and Function
- Place of Presentation
  Bethesda, MD, USA
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] メモリ-Th2 細胞は NK 細胞を活性化し抗腫瘍効果を持続させる/ Memory type2 helper T cells induce long-lasting anti-tumor immunity by activating natural killer cells2011
- Author(s)
  Ito, T., Kitajima, M., Tumes, J. D., Endo, Y., Onodera, A., Hashimoto, K., Motohashi, S., Yamashita, M., Nishimura, T., and Nakayama,T.
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] メモリ－Th2細胞はNK細胞を活性化し抗腫瘍効果を持続させる/ Memory type 2 helper T cells induce long-lasting anti-tumor immunity by activating natural killer cells.2011
- Author(s)
  Ito, T., Kitajima, M., Tumes, J. D., Endo, Y., Onodera, A., Hashimoto, K., Motohashi, S., Yamashita, M., Nishimura, T., and Nakayama, T.
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] GATA3 ChIP-sequence 解析を用いたTh2特異的遺伝子の転写調節機構の解明/Genome-wide analysis revealsunique regulation of transcription of Th2-specific genes by GATA32011
- Author(s)
  堀内周、小野寺淳、細川裕之、渡邊友紀子、中山俊憲
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Eomesodermin controls IL-5 production in memory Th2 cells through the inhibition of GATA3 activity2011
- Author(s)
  遠藤裕介、小野寺淳、細川裕之、中山俊憲.
- Organizer
  第21回Kyoto T Cell Conference
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] STAT6によって誘導されるポリコ－ムとトライソラックスの置換反応/ STAT6-mediated displacement of Polycomb by Trithorax complex establishes long-term maintenance of GATA3 expression in Th2 cells.2011
- Author(s)
  Onodera, A., Yamashita, M., Endo, Y., Kuwahara, M., Tofukuji, S., Hosokawa, H., Horiuchi, S., Watanabe, Y., and Nakayama, T
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] GATA3 ChIP-sequence解析を用いたTh2特異的遺伝子の転写調節機の解明/ Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3.2011
- Author(s)
  堀内周、小野寺淳、細川裕之、渡邊友紀子、中山俊憲
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA32011
- Author(s)
  Onodera, A., Horiuchi, S., Hosokawa, H., Watanabe, Y., Suzuki, Y., and Nakayama, T.
- Organizer
  NCI Symposium on Chromosome Structure and Function
- Place of Presentation
  Bethesda, MD, USA
- Year and Date
  2011-11-01
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] GATA3 ChIP-sequence解析を用いたTh2特異的遺伝子の転写調節機構の解明2011
- Author(s)
  堀内周、小野寺淳、細川裕之、渡邊友紀子、鈴木穣、中山俊憲
- Organizer
  第5回日本エピジェネティックス研究会
- Place of Presentation
  熊本
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Epigenetic control of memory Th2 cell function via Polycomb and Trithorax molecules2011
- Author(s)
  Nakayama,T.,and Onodera, A.
- Organizer
  EUThyme-Rolduc Meeting
- Place of Presentation
  Leeuwenhorst, NL
- Year and Date
  2011-05-24
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Eomesodermin controls IL-5 production inmemory Th2 cells through the inhibition of GATA3 activity2011
- Author(s)
  遠藤裕介、小野寺淳、細川裕之、中山俊憲
- Organizer
  第21回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] STAT6 によって誘導されるポリコームとトライソラックスの置換反応/STAT6-mediated displacement of Polycomb by Trithorax complex establishes long-term maintenance of GATA3 expression in Th2 cells2011
- Author(s)
  Onodera, A., Yamashita, M., Endo, Y., Kuwahara, M., Tofukuji, S., Hosokawa, H., Horiuchi, S., Watanabe, Y., and Nakayama,T.
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Regulation of memory Th2 cell function and allergic airway inflammation via polycomb and trithorax molecules2011
- Author(s)
  Nakayama, T., and Onodera, A.
- Organizer
  30^<th> Congress of the European Academy of Allergy and Clinical Immunology
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Epigenetic regulation of helper T cells by Polycomb and Trithorax complexes.
- Author(s)
  Onodera, A., Horiuchi, S., Sasaki, T., Hosokawa, H., Watanabe, Y., Suzuki, Y., and Nakayama, T.
- Organizer
  International Symposium on Genome Science
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Polycomb and Trithorax complexes control epigenetic memory of T helper cells.
- Author(s)
  Onodera, A., and Nakayama, T.
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館、京都府、京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25860351
[Presentation] Cellular memory of T helper type 2 cells controlled by GATA3 and epigenetic regulators.
- Author(s)
  Onodera, A., Horiuchi, S., Sasaki, T., Hosokawa, H., Watanabe, Y., and Nakayama, T.
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  幕張メッセ (千葉県千葉市)
- Data Source
  KAKENHI-PROJECT-25860351
[Presentation] Genome-wide gene expression profiling revealed a critical role for GATA3 in the maintenance of the Th2 cell phenotype.
- Author(s)
  Sasaki, T., Onodera, A., Hosokawa, H., Watanabe, Y., Horiuchi, S., Yamashita, J., and Nakayama, T.
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Regulation of memory CD4 T cell pool size and function by NKT cells in vivo.
- Author(s)
  Iwamura, C., Endo, Y., Onodera, A., Watanabe, Y., Suzuki, A., Kinjo, Y., and Nakayama, T.
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790523
[Presentation] Polycomb and Trithorax complexes control epigenetic memory of T helper cells.
- Author(s)
  Onodera, A. and Nakayama, T.
- Organizer
  International Symposium on Genome Science 2015
- Place of Presentation
  一橋講堂、東京都、千代田区
- Year and Date
  2015-01-20 – 2015-01-21
- Data Source
  KAKENHI-PROJECT-25860351
[Presentation] The polycomb protein Ezh2 regulates differentiation and plasticity of CD4 T helper type-1 and type-2 cells.
- Author(s)
  Tumes, J. D., Onodera, A., Hosokawa, H., Koseki, H., Suzuki, Y., Motohashi, S., and Nakayama, T.
- Organizer
  第24回Kyoto T cell Conference
- Place of Presentation
  京都平安ホテル、京都府、京都市
- Year and Date
  2014-05-16 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-25860351
[Presentation] Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORgt induction as downstream targets of Stat3.
- Author(s)
  Tanaka, S., Suto, A., Iwamoto, T., Suzuki, K., Takatori, H., Tamachi, T., Hirose, K., Onodera, A., Suzuki, J., Ohara, O., Yamashita, M., Nakayama, T., and Nakajima, H.
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館、京都府、京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25860351
[Presentation] The histone methyltransferase Ezh2 regulates differentiation and plasticity of CD4 T helper cells.
- Author(s)
  Tumes, D., Onodera, A., Suzuki, A., Shinoda, K., Endo, Y., Iwamura, C., Hosokawa, H., Koseki, H., Tokoyoda, K., Suzuki, Y., and Nakayama, T.
- Organizer
  AAI Annual Meeting
- Place of Presentation
  Hawaii Convention Center (Honolulu, Hawaii)
- Data Source
  KAKENHI-PROJECT-25860351
[Presentation] Generation and maintenance of pathogenic memory CD4 T cells.
- Author(s)
  Nakayama, T., Endo, Y., Onodera, A., and Tumes, D. J.
- Organizer
  The 3rd CSI/JSI/KAI Joint Symposium on Immunology
- Place of Presentation
  POSTECH Biotech Center(慶尚北道浦項市･韓国)
- Data Source
  KAKENHI-PROJECT-25860351
[Presentation] The trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.
- Author(s)
  Watanabe, Y., Onodera, A., Ichikawa, T., Obata-Ninomiya, K., Wada, T., Kiuchi, M., Morimoto, Y., Shinoda, K., Yagi, R., Motohashi, S., Hirahara, K., and Nakayama, T.
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館、京都府、京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25860351

1. 本橋新一郎 (60345022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 小林正芳 (10867857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HIRAHARA kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
4. KIMURA motoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. HOSOKAWA hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. SHINODA kenta

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. IWAMURA Chiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. HIROSE Kohichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. SUTO Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. SUZUKI Kotaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. TAKATORI Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 中山俊憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
13. 小久保幸太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 木内政宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 関直彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 田中知明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 佐久間一基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 中島裕史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 岡本美孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 岡本好海

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 高見真理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Onodera Atsushi 小野寺 淳

ONODERA Atsushi 小野寺 淳

Research Projects

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Co-Researchers

膠芽腫に対する遺伝子改変iPS細胞由来NKT細胞を用いたがん免疫療法の開発

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DNAメチル化異常による病的炎症発生機構の解明Principal Investigator

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Heterochromatin dysfunction and its related diseases induced by impaired DNA demethylationPrincipal Investigator

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Active and passive DNA demethylation in T cellsPrincipal Investigator

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Epigenetic regulation of the memory T cell responsePrincipal Investigator

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Polycomb and Trithorax complexes control epigenetic memory of T helper cellsPrincipal Investigator

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Molecular basis of Polycomb and Trithorax complexes in the maintenance of immunological memoryPrincipal Investigator

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[Book] 基礎から学ぶ免疫学2023

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[Book] 上田宏の思い出2023

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[Book] エッセンシャル免疫学2023

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[Book] 免疫生物学原書第9版2019

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[Book] Gene Expression and Regulation in Mammalian Cells - Transcription From General Aspects2018

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[Book] Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development2014

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Onodera Atsushi 小野寺淳

ONODERA Atsushi 小野寺淳