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Oshima Yusuke  大嶋 佑介

… Alternative Names

OSHIMA YUSUKE  大嶋 佑介

YUSUKE Oshima  大嶋 佑介

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Researcher Number 10586639
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-2304-8600
Affiliation (Current) 2025: 富山大学, 学術研究部工学系, 特命教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 富山大学, 学術研究部工学系, 准教授
2018 – 2020: 大分大学, 医学部, 客員研究員
2017: 東北大学, 医工学研究科, 研究支援者
2016: 愛媛大学, 医学系研究科, 助教
2014: 愛媛大学, 医学(系)研究科(研究院), 助教
2012 – 2013: 愛媛大学, 医学部附属病院, 助教
2012 – 2013: 愛媛大学, 医学部附属病院, 助教(病院教員)
Review Section/Research Field
Principal Investigator
Medical systems / Medical systems
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 90130:Medical systems-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 21060:Electron device and electronic equipment-related / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90110:Biomedical engineering-related / Orthopaedic surgery
Keywords
Principal Investigator
非線形光学イメージング / 非線形光学 / 顕微ラマン分光 / 診断 / SHGイメージング / ラマン分光 / 無染色イメージング / 第2高調波発生 / イメージング / トランスレーショナルリサーチ … More / 疾患モデル / がん転移 / 軟骨変性 / がん / 骨質 / 骨粗鬆症 / ライブセルイメージング / がん診断 / 2光子蛍光 / ラマンイメージング / 内視鏡 / 診断システム / 多光子励起蛍光 / 中空ファイバ / 深部イメージング … More
Except Principal Investigator
ラマン分光法 / ヒルシュスプルング病 / 腹膜播種 / 光線療法 / イメージング / 変形性関節症 / 軟骨変性 / 軟骨 / 環境測定 / 非破壊分析 / ウイルス / ラマン分光分析 / リアルタイム分析 / ヒト感染性ウイルス / 多変量解析 / 生細胞分析 / ウイルス検出 / ラマン分光学 / 消化器癌 / 腹膜転移 / 光免疫療法 / 時短パルスレーザー / AI手術支援 / オルガネラ / 加齢 / ミトコンドリア / 老化 / 卵子 / 反回神経 / 反回神経麻痺 / 食道癌 / パルスレーザー / 光線治療 / 光バイオプシー / 畳み込みニューラルネットワーク / 回折限界 / マルチコアファイバ / 被写界深度 / スペクトル符号化法 / 蛍光イメージング / マルチモードファイバ / ファイバイメージング / スペクトル符号化 / コンピュテーショナルイメージング / 内視鏡 / 光ファイバ / 大腸癌治療 / 抗炎症光線 / 微小環境 / 癌治療 / 粘液癌 / 胃癌 / 大腸癌 / オルガノイド / 癌微小環境 / 再生軟骨 / 変形性関節 / 第2次高調波 / 変形性膝関節症 / 軟骨再生 / 第2次高調波 / バイオイメージング / ラマン 分光 / がん治療 / 転移 / ラマン分光 / がん微小環境 / がん / 2光子励起顕微鏡 / 二光子励起 / Smurf / 2光子励起 / SHG / TGF-β Less
  • Research Projects

    (15 results)
  • Research Products

    (138 results)
  • Co-Researchers

    (27 People)
  •  Development of AI-assisted laparoscopic surgical system with Raman spectroscopy for Hirschsprung's Disease

    • Principal Investigator
      小川 雄大
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Oita University
  •  Novel photoimmunotherapy using light-sensitive drugs and ultrashort pulsed laser for peritoneal dissemination of cancer

    • Principal Investigator
      白下 英史
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Oita University
  •  オルガネラ改変に基づく加齢卵子の”質”改善法の開発

    • Principal Investigator
      小池 誠一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      University of Toyama
  •  Principles for the development of an ultra-thin imaging system by the spectral encoding

    • Principal Investigator
      Katagiri Takashi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 21060:Electron device and electronic equipment-related
    • Research Institution
      University of Toyama
  •  Development of an intraoperative diagnosis for Hirschsprung's disease using optical biopsy technology

    • Principal Investigator
      Ogawa Katsuhiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Oita University
  •  Development of new photo dynamic therapy for peritoneal dissemination of gastric cancer

    • Principal Investigator
      Shiroshita Hidefumi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Oita University
  •  Development of an intraoperative identification of the recurrent nerve based on Raman spectroscopy to improve the prognosis of esophageal cancer

    • Principal Investigator
      SHIBATA TOMOTAKA
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Oita University
  •  Development of practical techniques for Raman detection of human infectious virus

    • Principal Investigator
      佐藤 英俊
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Kwansei Gakuin University
  •  Development of new treatment method for colorectal cancer based on cancer microenvironment control using anti-inflammatory light

    • Principal Investigator
      Hiratsuka Takahiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Oita University
  •  Raman spectroscopic study of cancer metastasis and diagnosis.

    • Principal Investigator
      Koga Shigehiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Ehime University
  •  Pathophysiology analysis and clinical application development of cartilage degenerative diseases based on label-free imaging technology

    • Principal Investigator
      Kiyomatsu Hiroshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Ehime University
  •  Label-free imaging technique based on nonlinear optics in biological tissues for medical applicationPrincipal Investigator

    • Principal Investigator
      OSHIMA YUSUKE
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Medical systems
    • Research Institution
      Oita University
      Tohoku University
      Ehime University
  •  Nonliner optical imaging for deep tissue using hollow fiber bundlePrincipal Investigator

    • Principal Investigator
      YUSUKE Oshima
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical systems
    • Research Institution
      Ehime University
  •  Analysis of the TGF-b signaling in cartilage by nonlinear optics imaging combined with genetic engineering techniques

    • Principal Investigator
      MIURA Hiromasa
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Ehime University
  •  Label-free imaging technique based on nonlinear optics in biological tissues for medical applicationPrincipal Investigator

    • Principal Investigator
      OSHIMA Yusuke
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Medical systems
    • Research Institution
      Ehime University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book Patent

  • [Book] バイオイメージングの現状と展望2014

    • Author(s)
      今村健志,疋田温彦,大嶋佑介,飯村忠浩
    • Total Pages
      3
    • Publisher
      インナービジョン
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Book] 「非線形光学を駆使した生体蛍光癌イメージング」医学のあゆみ2014

    • Author(s)
      今村健志、大嶋佑介、疋田温彦、古賀繁宏
    • Total Pages
      6
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Book] 「一枚の写真 生体深部を高速かつ広い視野で観察できる光シート顕微鏡」OplusE2014

    • Author(s)
      大嶋佑介
    • Total Pages
      2
    • Publisher
      アドコムメディア株式会社
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Book] The Bone小誌第125号 (2014年4月号)「骨バイオイメージング」ラマン分光法による骨組織の分子計測と骨質評価への応用2014

    • Author(s)
      大嶋佑介,飯村忠浩,疋田温彦,今村健志
    • Total Pages
      6
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Book] 「細胞イメージング技術と呼吸器」The Lung perspectives Vol. 22, No. 4 (2014年11月14日発行)「新技術の呼吸器への応用を考える」2014

    • Author(s)
      今村健志、大嶋佑介、岡崎幹生、佐野由文
    • Total Pages
      4
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Book] 「In vivo imagingの最前線」整形・災害外科2013

    • Author(s)
      今村健志,疋田温彦,大嶋佑介
    • Publisher
      金原出版株式会社
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Book] 「骨・軟骨組織の生体光イメージング」月刊誌CLINICAL CALCIUM2013

    • Author(s)
      今村健志、疋田温彦、大嶋佑介、飯村忠浩
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Book] 先端バイオマテリアルハンドブック 12節 生体組織の分子組成を直接的に計測できる極細径ラマンプローブ2012

    • Author(s)
      佐藤英俊, 大嶋佑介
    • Publisher
      株式会社 エヌ・ティー・エス
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Journal Article] Intraoperative tissue identification for gastrointestinal disorder by Raman spectroscopy and machine learning2024

    • Author(s)
      Oshima Y, Ogawa K, Fumuro H, Katagiri T, Inomata M
    • Journal Title

      Proceedings of SPIE (The International Society for Optical Engineering), Photonics West, Biomedical Vibrational Spectroscopy

      Volume: 1283903 Pages: 18-18

    • DOI

      10.1117/12.3005335

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08781
  • [Journal Article] Prognostic potential and pathological validation of a diagnostic application using Raman spectroscopy in the characterization of degenerative changes in the cartilage of the humeral head2022

    • Author(s)
      Asaoka Ryuji、Kiyomatsu Hiroshi、Miura Hiromasa、Jono Akihiro、Kinoshita Tomofumi、Takao Masaki、Katagiri Takashi、Oshima Yusuke
    • Journal Title

      Journal of Biomedical Optics

      Volume: 27 Issue: 11 Pages: 115002-115002

    • DOI

      10.1117/1.jbo.27.11.115002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19598, KAKENHI-PROJECT-21H01385
  • [Journal Article] Attenuated Total Reflection Far-Ultraviolet (ATR-FUV) Spectroscopy is a Sensitive Tool for Investigation of Protein Adsorption2022

    • Author(s)
      Hashimoto Kosuke、Morisawa Yusuke、Tortora Mariagrazia、Rossi Barbara、Ozaki Yukihiro、Sato Hidetoshi
    • Journal Title

      Applied Spectroscopy

      Volume: - Issue: 7 Pages: 793-800

    • DOI

      10.1177/00037028211070835

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K18047, KAKENHI-PROJECT-23K21861
  • [Journal Article] Label-free detection of human enteric nerve system using Raman spectroscopy: A pilot study for diagnosis of Hirschsprung disease2021

    • Author(s)
      Katsuhiro Ogawa, Yusuke Oshima, Tsuyoshi Etoh, Yushi Kaisyakuji, Manabu Tojigamori, Yasuharu Ohno, Norio Shiraishi, Masafumi Inomata
    • Journal Title

      Journal of Pediatric Surgery

      Volume: 56 Issue: 7 Pages: 1150-1156

    • DOI

      10.1016/j.jpedsurg.2021.03.040

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08781
  • [Journal Article] ラマン分光法による軟骨評価と診断治療への応用2020

    • Author(s)
      清松 悠, 日野 和典, 三浦 裕正, 大嶋 佑介
    • Journal Title

      日本関節病学会誌

      Volume: 39 Pages: 9197-9197

    • NAID

      130007903720

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19927
  • [Journal Article] Trefoil factor 2 activation of CXCR4 requires calcium mobilization to drive epithelial repair in gastric organoids2019

    • Author(s)
      Engevik Kristen A.、Hanyu Hikaru、Matthis Andrea L.、Zhang Tongli、Frey Mark R.、Oshima Yusuke、Aihara Eitaro、Montrose Marshall H.
    • Journal Title

      The Journal of Physiology

      Volume: 597 Issue: 10 Pages: 2673-2690

    • DOI

      10.1113/jp277259

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Journal Article] 共焦点レーザー顕微鏡と多光子励起顕微鏡2019

    • Author(s)
      大嶋佑介
    • Journal Title

      Clinical Neuroscience 中外医学社

      Volume: 36 Pages: 898-902

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Journal Article] 多光子励起顕微鏡の進歩と医学応用2019

    • Author(s)
      大嶋 佑介,佐川 倫子,平塚 孝宏,衛藤 剛,猪股 雅史
    • Journal Title

      レーザー研究

      Volume: 47 Pages: 89-93

    • NAID

      130008074040

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Journal Article] Detection of changes in bone quality of osteoporotic model induced by sciatic nerve resection by using Raman spectroscopy2018

    • Author(s)
      Ishimaru Yasumitsu、Oshima Yusuke、Imai Yuuki、Iimura Tadahiro、Takanezawa Sota、Hino Kazunori、Miura Hiromasa
    • Journal Title

      Proceedings of SPIE

      Volume: 1049722 Pages: 1049722-1049722

    • DOI

      10.1117/12.2291258

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Journal Article] Raman spectroscopic analysis for gastric and colorectal cancer in surgical treatment toward molecular-guided surgery2018

    • Author(s)
      Shigehiro Koga, Yuji Watanabe, Yusuke Oshima
    • Journal Title

      Proc. SPIE

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K12063
  • [Journal Article] Evaluation of degenerative changes in articular cartilage of osteoarthritis by Raman spectroscopy2018

    • Author(s)
      Oshima Yusuke、Kiyomatsu Hiroshi、Miura Hiromasa、Ishimaru Yasumitsu、Hino Kazunori
    • Journal Title

      Proceedings of SPIE

      Volume: 104971 Pages: 104971-104971

    • DOI

      10.1117/12.2291383

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05912, KAKENHI-PROJECT-18K19927
  • [Journal Article] Raman spectroscopic analysis for gastric and colorectal cancer in surgical treatment toward molecular-guided surgery2018

    • Author(s)
      Oshima Yusuke、Koga Shigehiro、Watanabe Yuji
    • Journal Title

      Proceedings of SPIE

      Volume: 1047806 Pages: 1047806-1047806

    • DOI

      10.1117/12.2291435

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Journal Article] Raman Spectroscopic Analysis to Detect Reduced Bone Quality after Sciatic Neurectomy in Mice.2018

    • Author(s)
      Ishimaru Y, Oshima Y, Imai Y, Iimura T, Takanezawa S, Hino K, Miura H
    • Journal Title

      Molecules

      Volume: 23 Issue: 12 Pages: 3081-3081

    • DOI

      10.3390/molecules23123081

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19649, KAKENHI-PROJECT-18H02983, KAKENHI-PROJECT-16H05912
  • [Journal Article] Altered Gene Expression of RNF34 and PACAP Possibly Involved in Mechanism of Exercise-Induced Analgesia for Neuropathic Pain in Rats2017

    • Author(s)
      Yamaoka Shintaro、Oshima Yusuke、Horiuchi Hideki、Morino Tadao、Hino Masayuki、Miura Hiromasa、Ogata Tadanori
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 18 Issue: 9 Pages: 1962-1962

    • DOI

      10.3390/ijms18091962

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Journal Article] Raman spectroscopy for cancer detection and characterization in metastasis models2017

    • Author(s)
      Shigehiro Koga, Yusuke Oshima, Mitsunori Sato, Kei Ishimaru, Motohira Yoshida, Yuji Yamamoto, Yusuke Matsuno, Yuji Watanabe
    • Journal Title

      Proceedings of SPIE

      Volume: 10060 Pages: 100600O-100600O

    • DOI

      10.1117/12.2250748

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Journal Article] Label-free characterization of articular cartilage in osteoarthritis model mice by Raman spectroscopy2017

    • Author(s)
      Yusuke Oshima, Mayu Akehi, Hiroshi Kiyomatsu, Hiromasa Miura
    • Journal Title

      Proceedings of SPIE

      Volume: 10054 Pages: 1005406-1005406

    • DOI

      10.1117/12.2250673

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Journal Article] Bisphenol A Inhibits Cell Proliferation and Reduces the Motile Potential of Murine LM8 Osteosarcoma Cells2016

    • Author(s)
      T. Kidani, R. Yasuda, J. Miyawaki, Y. Oshima, H. Miura and H. Masuno
    • Journal Title

      Anticancer Res

      Volume: 37 Issue: 4 Pages: 1711-1722

    • DOI

      10.21873/anticanres.11503

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Journal Article] Quantitative imaging of fibrotic and morphological changes in liver of non-alcoholic steatohepatitis (NASH) model mice by second harmonic generation (SHG) and auto-fluorescence (AF) imaging using two-photon excitation microscopy (TPEM).2016

    • Author(s)
      Yamamoto S, Oshima Y, Saitou T, Watanabe T, Miyake T, Yoshida O, Tokumoto Y, Abe M, Matsuura B, Hiasa Y, Imamura T
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 8 Pages: 277-283

    • DOI

      10.1016/j.bbrep.2016.09.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05952, KAKENHI-PROJECT-15H04962, KAKENHI-PROJECT-16H05912, KAKENHI-PROJECT-15K15553, KAKENHI-PROJECT-16K15328, KAKENHI-PROJECT-16K18578
  • [Journal Article] Changes in chemical composition of bone matrix in ovariectomized (OVX) rats detected by Raman spectroscopy and multivariate analysis2015

    • Author(s)
      Yusuke Oshima, Tadahiro Iimura, Takashi Saitou, Takeshi Imamura
    • Journal Title

      SPIE Proceedings

      Volume: 9303 Pages: 9303-9303

    • DOI

      10.1117/12.2078787

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Journal Article] Quantitative SHG imaging in osteoarthritis model mice, implying a diagnostic application2015

    • Author(s)
      Hiroshi Kiyomatsu, Yusuke Oshima, Takashi Saitou, Tsuyoshi Miyazaki, Atsuhiko Hikita, Hiromasa Miura, Tadahiro Iimura, Takeshi Imamura
    • Journal Title

      Biomedical Optics Express

      Volume: 6 Issue: 2 Pages: 405-420

    • DOI

      10.1364/boe.6.000405

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24680060, KAKENHI-PROJECT-26293392
  • [Journal Article] Wide field intravital imaging by two-photonexcitation digital-scanned light-sheet microscopy (2p-DSLM) with a high-pulse energy laser2014

    • Author(s)
      Atsushi Maruyama, Yusuke Oshima*, Hiroko Kajiura-Kobayashi, Shigenori Nonaka, Takeshi Imamura, Kiyoshi Naruse
    • Journal Title

      Biomedical Optics Express

      Volume: 5 Issue: 10 Pages: 3311-3325

    • DOI

      10.1364/boe.5.003311

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24680060, KAKENHI-PROJECT-26650112
  • [Journal Article] In vivo imaging of spinal cord in contusion injury model mice by multi-photon microscopy2014

    • Author(s)
      Y. Oshima, H. Horiuchi, T. Ogata, A. Hikita, H. Miura, and T. Imamura
    • Journal Title

      Proc. SPIE

      Volume: 8947 Pages: 8947-7

    • DOI

      10.1117/12.2041042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24650297, KAKENHI-PROJECT-24680060
  • [Journal Article] Ultrasensitive imaging of Ca2+ dynamics in pancreatic acinar cells of Yellow Cameleon-Nano transgenic mice2014

    • Author(s)
      Yusuke Oshima, Takeshi Imamura, Atsuko Shintani, Hiroko Kajiura-Kobayashi, Terumasa Hibi, Takeharu Nagai, Shigenori Nonaka, Tomomi Nemoto
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 15 Issue: 11 Pages: 19971-19986

    • DOI

      10.3390/ijms151119971

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22113005, KAKENHI-PROJECT-24680060, KAKENHI-PROJECT-25560411, KAKENHI-PROJECT-26242082, KAKENHI-PROJECT-26650112
  • [Journal Article] In vivo subcellular imaging of tumors in mouse models using a fluorophore-conjugated anti-CEA antibody in TPEM2014

    • Author(s)
      Shigehiro Koga, Yusuke Oshima, Naoki Honkura, Tadahiro Iimura, Kenji Kameda, Koichi Sato, Motohira Yoshida, Yuji Yamamoto, Yuji Watanabe, Atsuhiko Hikita, and Takeshi Imamura
    • Journal Title

      Cancer Science

      Volume: 105(10) Issue: 10 Pages: 1299-1306

    • DOI

      10.1111/cas.12500

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22113004, KAKENHI-PROJECT-24680060, KAKENHI-PROJECT-26293392
  • [Journal Article] Intravital multiphoton fluorescence imaging and optical manipulation of spinal cord in mice, using a compact fiber laser system2014

    • Author(s)
      Yusuke Oshima, Hideki Horiuch, Naoki Honkura, Atsuhiko Hikita, Tadanori Ogata, Hiromasa Miura, Takeshi Imamura
    • Journal Title

      Lasers in Surgery and Medicine

      Volume: 46 Issue: 7 Pages: 563-572

    • DOI

      10.1002/lsm.22266

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Journal Article] 無染色イメージングの技術開発と医療応用 : 細胞のラマン分光から生体の非線形光学イメージングへの技術展開2013

    • Author(s)
      大嶋佑介
    • Journal Title

      光アライアンス

      Volume: 24 Pages: 6-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Journal Article] Light sheet-excited spontaneous Raman imaging of a living fish by optical sectioning in a wide field Raman microscope.2012

    • Author(s)
      Yusuke Oshima, Hidetoshi Sato, Hiroko Kajiura- Kobayashi, Tetsuaki Kimura, Kiyoshi Naruse, Shigenori Nonaka
    • Journal Title

      Optics Express

      Volume: 20 Issue: 15 Pages: 16195-204

    • DOI

      10.1364/oe.20.016195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Journal Article] プローブレスイメージング(ラマン分光法, SHG/THG)の診断応用2012

    • Author(s)
      大嶋佑介
    • Journal Title

      病理と臨床

      Volume: 30 Pages: 755-761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Journal Article] 短時間での広視野ラマンイメージングが可能に2012

    • Author(s)
      野中茂紀, 大嶋佑介
    • Journal Title

      OplusE

      Volume: 34 Pages: 996-996

    • Data Source
      KAKENHI-PROJECT-24680060
  • [Patent] 観察装置2017

    • Inventor(s)
      大嶋佑介、鈴木智
    • Industrial Property Rights Holder
      大嶋佑介、鈴木智
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-085581
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] 近赤外超短パルスレーザーを用いた光線力学療法における2光子励起の検討2024

    • Author(s)
      屋敷翔紀,小川雄大,白下英史,猪股雅史,片桐崇史,大嶋佑介
    • Organizer
      レーザー学会学術講演会第44回年次大会
    • Data Source
      KAKENHI-PROJECT-21K08782
  • [Presentation] Intraoperative tissue identification for gastrointestinal disorder by Raman spectroscopy and machine learning2024

    • Author(s)
      Oshima Y, Ogawa K, Fumuro H, Katagiri T, Inomata H
    • Organizer
      SPIE Photonics West 2024
    • Data Source
      KAKENHI-PROJECT-21K08781
  • [Presentation] スペクトル符号化単一ファイバイメージングの光学的性能2024

    • Author(s)
      石川真太郎、小池亮、大嶋佑介、片桐 崇史
    • Organizer
      レーザー学会学術講演会第44回年次大会、H02-17a-IV-03
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 近赤外超短パルスレーザーを用いた光線力学療法における2光子励起の検討2024

    • Author(s)
      屋敷翔紀、小川雄大、白下英史、猪股雅史、片桐崇史、大嶋佑介
    • Organizer
      レーザー学会学術講演会第44回年次大会、I10-19p-II-02
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 消化器外科手術におけるラマン分光法の実用化を目指した腸管組織の ex vivo 解析2024

    • Author(s)
      布目遼平、文室温人、小川雄大、白下英史、猪股雅史、片桐崇史、大嶋佑介
    • Organizer
      レーザー学会学術講演会第44回年次大会、I02-17a-II-03
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 低侵襲手術のための骨・軟骨組織のラマンスペクトル計測・解析法の検討2024

    • Author(s)
      戸田航輔、清松悠、山岡慎大朗、木下智文、髙尾正樹、片桐崇史、大嶋佑介
    • Organizer
      レーザー学会学術講演会第44回年次大会、A08-18p-VI-06
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] スペクトル符号化イメージングにおける構造化照明を用いた較正法の検討2024

    • Author(s)
      陳 子せん、小山 卓耶、大嶋 佑介、片桐 崇史
    • Organizer
      第71回応用物理学会春季学術講演会、23a-12A-2
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 鏡視下光診断デバイスとしてのラマンプローブの開発2024

    • Author(s)
      文室温人、片桐崇史、小川雄大、白下英史、衛藤剛、猪股雅史、清松悠、高尾正樹、大嶋佑介
    • Organizer
      レーザー学会学術講演会第44回年次大会、I02-17a-II-04
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] Intraoperative tissue identification for gastrointestinal disorder by Raman spectroscopy and machine learning2024

    • Author(s)
      Yusuke Oshima、Katsuhiro Ogawa、Haruto Fumuro、Takashi Katagiri、Masafumi Inomata
    • Organizer
      Proc. SPIE、12839-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 深層学習による非線形光学イメージの解析と臨床応用に向けた試み2024

    • Author(s)
      福澤拓人、大嶋佑介、片桐崇史
    • Organizer
      レーザー学会学術講演会第44回年次大会、LSJ/I01-17a-II-03-8
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] Deep tissue optical absorption spectroscopy using laser-induced ultrasonic pulse2023

    • Author(s)
      児玉佳祐、大嶋佑介、片桐崇史
    • Organizer
      The 44th Symposium on UltraSonic Electronics、1P1-1
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 散乱媒質中の吸光度計測における超音波誘起仮想導波路の効果2023

    • Author(s)
      児玉佳祐、大嶋佑介、片桐崇史
    • Organizer
      第84回応用物理学会秋季学術講演会、20p-A305-4
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] スペクトル符号化単一ファイバイメージングにおける標本化法の検討2023

    • Author(s)
      野々目久祥、大嶋佑介、片桐崇史
    • Organizer
      第84回応用物理学会秋季学術講演会、20p-A308-17
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] スペクトル符号化法による単一ファイバイメージング2023

    • Author(s)
      石川真太郎、大嶋佑介、片桐崇史
    • Organizer
      電子情報通信学会 光ファイバ応用技術研究会、OFT2023-8
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 光イメージング技術を用いたヒルシュスプルング病における無神経節腸管の形態学的解析・病理学的解析2023

    • Author(s)
      大嶋佑介,小川雄大,衛藤剛,大西峻,家入里志,駄阿勉,猪股雅史
    • Organizer
      第13回癌・炎症と抗酸化研究会
    • Data Source
      KAKENHI-PROJECT-21K08781
  • [Presentation] ラマン分光法を用いたヒルシュスプルング病診断の臨床応用への取り組み2023

    • Author(s)
      小川 雄大、大嶋 佑介、松本 悠希、松本 紘明、皆尺寺 悠史、大西 峻、白下 英史、衛藤 剛、家入 里志、猪股 雅史
    • Organizer
      第60回日本小児外科学会総会
    • Data Source
      KAKENHI-PROJECT-21K08781
  • [Presentation] Classification of Myeloma Cell on Raman Spectroscopy with Machine Learning2023

    • Author(s)
      Noritaka Fujisawa、Akinori taketani、Akinori Wada、Tsutomu Sato、Keiichi Koizumi、Takashi Katagiri、Yusuke Oshima
    • Organizer
      APLS2023、PGTu-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 大面積生体ラマン分光計測~励起光面積が背景光強度に与える影響~2023

    • Author(s)
      桐島潤、大嶋佑介、片桐崇史
    • Organizer
      第84回応用物理学会秋季学術講演会、20p-A305-18
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 赤外中空ファイバカプラの設計2023

    • Author(s)
      山川涼、大嶋佑介、中川広務、片桐崇史
    • Organizer
      電子情報通信学会 光ファイバ応用技術研究会、OFT2023-7
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 術中に無神経節腸管を同定するためのラマン分光システムの開発2022

    • Author(s)
      松本 悠希、小川 雄大、衛藤 剛、猪股 雅史、片桐 崇史、大嶋 佑介
    • Organizer
      レーザー学会学術講演会第42回年次大会
    • Data Source
      KAKENHI-PROJECT-21K08781
  • [Presentation] Mid-infrared hollow fiber couplers2022

    • Author(s)
      Masanori Kato, Yuji Matsuura, Yusuke Oshima, Takashi Katagiri
    • Organizer
      Proc. SPIE PC11953, Optical Fiber and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXII
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] A NEW OPTICAL BIOPSY TECHNIQUE FOR DETECTION OF AGANGLIONOSIS IN HIRSHSPRUNG DISEASE BY USING RAMAN SPECTROSCOPY COMBINED WITH DEEP LEARNING2022

    • Author(s)
      K. Ogawa*1, Y. Oshima2, Y. Matsumoto2, K. Tamura2, S. Onishi3, T. Etoh1, S. Ieiri3, M. Inomata1
    • Organizer
      International surgical week 2022
    • Data Source
      KAKENHI-PROJECT-21K08781
  • [Presentation] Raman Endoscope for Diagnosis of Eosionphil Esophagitis2022

    • Author(s)
      H. Sato, R. Zakaria, T. Watanabe, S. Ishihara, k. Iwasaki, B. B. Andriana, K. Hashimoto, T. Yamamoto, N. Oshima
    • Organizer
      SCIX2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K21861
  • [Presentation] ラマン分光法を用いた卵子の老化のメカニズム解析2022

    • Author(s)
      出相貴史、小池誠一、朝岡竜士、片桐崇史、大嶋佑介
    • Organizer
      43回レーザー学会学術講演会
    • Data Source
      KAKENHI-PROJECT-22K19598
  • [Presentation] 術中病理診断を目的としたヒト腸管の共焦点顕微ラマン測定法の検討2022

    • Author(s)
      松本悠希,小川 雄大,衛藤 剛,猪股雅史,田村海,竹中崚,片桐崇史,大嶋佑介
    • Organizer
      光・量子デバイス研究会
    • Data Source
      KAKENHI-PROJECT-21K08781
  • [Presentation] 側面研磨型中空光ファイバカプラの特性評価2021

    • Author(s)
      加藤仁教, 松浦祐司, 大嶋佑介, 片桐崇史
    • Organizer
      第82回応用物理学会秋季学術講演会
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 圧縮ラマンイメージングの精度評価2021

    • Author(s)
      舟橋諒, 大嶋佑介, 片桐崇史
    • Organizer
      第82回応用物理学会秋季学術講演会
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 中赤外光用光コンバイナの製作2021

    • Author(s)
      加藤仁教, 松浦祐司, 大嶋佑介, 片桐崇史
    • Organizer
      レーザー学会学術講演会第42回年次大会
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 変形性肩関節症の軟骨組織のラマンスペクトル測定によるメカニズムの解明2021

    • Author(s)
      朝岡 竜士、清松 悠、三浦 裕正、片桐 崇史、大嶋 祐介
    • Organizer
      一般社団法人レーザー学会学術講演会第41回年次大会
    • Data Source
      KAKENHI-PROJECT-18K19927
  • [Presentation] 波長可変スペックル照明を用いた単一ファイバイメージングシステムの測定精度改善2021

    • Author(s)
      川上友佑, 大嶋佑介, 片桐崇史
    • Organizer
      レーザー学会学術講演会第42回年次大会
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] スペクトル符号化単一ファイバイメージングの空間分解能2021

    • Author(s)
      小池亮, 大嶋佑介, 片桐崇史
    • Organizer
      第82回応用物理学会秋季学術講演会
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] スペクトル符号化による極細径ファイバイメージングの被写界深度2021

    • Author(s)
      石川真太郎, 大嶋佑介, 片桐崇史
    • Organizer
      レーザー学会学術講演会第42回年次大会
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 大面積散乱光検出のためのエタンデュ低減システムの提案2021

    • Author(s)
      西田翔吾, 大嶋佑介, 片桐崇史
    • Organizer
      第82回応用物理学会秋季学術講演会
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] 術中に無神経節腸管を同定するためのラマン分光システムの開発2021

    • Author(s)
      松本悠希, 小川雄大, 衛藤剛, 猪股雅文, 片桐崇史, 大嶋佑介
    • Organizer
      レーザー学会学術講演会第42回年次大会
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] レーザー誘起衝撃波により形成される擬似的導波路中の光伝搬2021

    • Author(s)
      鈴木雄大, 大嶋佑介, 片桐崇史
    • Organizer
      第82回応用物理学会秋季学術講演会
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] ラマン分光法を用いたヒルシュスプルング病における腸管壁内神経叢の術中同定法の開発2021

    • Author(s)
      小川 雄大、大嶋 佑介、皆尺寺 悠史、上田 貴威、當寺ヶ盛 学、白下 英史、衛藤 剛、白石 憲男、猪股 雅史
    • Organizer
      第121回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-21K08781
  • [Presentation] ラマン分光法によるマウス免疫細胞のフェノタイプ解析2021

    • Author(s)
      文室温人, 山本武, 竹谷皓規, 小泉桂一, 片桐崇史, 大嶋佑介
    • Organizer
      レーザー学会学術講演会第42回年次大会
    • Data Source
      KAKENHI-PROJECT-21H01385
  • [Presentation] ラマン分光・非線形光学イメージングによる骨軟骨疾患の診断応用2019

    • Author(s)
      大嶋佑介、清松悠、明比麻由、石丸泰光、日野和典、三浦裕正
    • Organizer
      レーザー学会学術講演会第39回年次大会
    • Data Source
      KAKENHI-PROJECT-18K19927
  • [Presentation] ラマン分光・非線形光学イメージングによる軟骨評価と治療診断への応用2019

    • Author(s)
      大嶋佑介
    • Organizer
      第47回日本関節病学会シンポジウム(招待)
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19927
  • [Presentation] ラマン分光法による術中光診断技術の開発2019

    • Author(s)
      大嶋佑介
    • Organizer
      第10回 癌・炎症と抗酸化研究会
    • Data Source
      KAKENHI-PROJECT-18K12063
  • [Presentation] ラマン分光法を用いたヒルシュスプルング病における無神経節腸管の可視化2019

    • Author(s)
      小川雄大、大嶋佑介、平塚孝宏、赤木智徳、鈴木浩輔、柴田智隆、上田貴威、當寺ヶ盛学、白下英史、衛藤剛、白石憲男、猪股雅史
    • Organizer
      レーザー学会学術講演会第39回年次大会
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] ラマン分光・非線形光学イメージングによる骨軟骨疾患の診断応用2019

    • Author(s)
      大嶋佑介、清松悠、明比麻由、石丸泰光、日野和典、三浦裕正
    • Organizer
      レーザー学会学術講演会第39回年次大会
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] 消化器外科手術におけるラマン分光・非線形光学イメージング技術の実用化をめざして2018

    • Author(s)
      大嶋佑介
    • Organizer
      一般社団法人レーザー学会「レーザーバイオ医療」技術専門委員会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] ラマン分光法・非線形光学による術中がんイメージング技術の開発2018

    • Author(s)
      大嶋佑介、古賀繁宏、渡部祐司
    • Organizer
      第57回日本生体医工学会大会
    • Data Source
      KAKENHI-PROJECT-18K12063
  • [Presentation] 癌診断・癌治療のための光イメージング技術最前線2018

    • Author(s)
      大嶋佑介
    • Organizer
      第9回癌・炎症と抗酸化研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] ラマン分光法・非線形光学による術中がんイメージング技術の開発2018

    • Author(s)
      大嶋佑介、古賀繁宏、渡部祐司
    • Organizer
      第57回日本生体医工学会大会
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] ラマン顕微鏡を用いた糖尿病モデルマウスの骨質の計測2018

    • Author(s)
      石丸泰光、大嶋佑介、今井祐記、飯村忠浩、高根沢聡太、日野和典、三浦裕正
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] Raman spectroscopy for cancer detection and characterization in metastasis models2017

    • Author(s)
      Shigehiro Koga, Yusuke Oshima, Mitsunori Sato, Kei Ishimaru, Motohira Yoshida, Yuji Yamamoto, Yusuke Matsuno, Yuji Watanabe
    • Organizer
      Photonics West2017
    • Place of Presentation
      San Francisco
    • Year and Date
      2017-02-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] Detection of changes in bone quality of osteoporotic model induced by sciatic nerve resection by using Raman spectroscopy2017

    • Author(s)
      Ishimaru Yasumitsu、Oshima Yusuke、Imai Yuuki、Iimura Tadahiro、Takanezawa Sota、Hino Kazunori、Miura Hiromasa
    • Organizer
      Photonics West2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] Label-free characterization of articular cartilage in osteoarthritis model mice by Raman spectroscopy,2017

    • Author(s)
      Yusuke Oshima, Mayu Akehi, Hiroshi Kiyomatsu Hiromasa Miura
    • Organizer
      Photonics West2017
    • Place of Presentation
      San Francisco
    • Year and Date
      2017-01-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] ラマン分光・イメージングによる骨粗鬆症モデルの骨質評価2017

    • Author(s)
      大嶋佑介,石丸泰光,三浦裕正,今井祐記,飯村忠浩
    • Organizer
      第37回日本骨形態計測学会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] Evaluation of degenerative changes in articular cartilage of osteoarthritis by Raman spectroscopy2017

    • Author(s)
      Oshima Yusuke、Kiyomatsu Hiroshi、Miura Hiromasa、Ishimaru Yasumitsu、Hino Kazunori
    • Organizer
      Photonics West2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] Raman spectroscopic analysis for gastric and colorectal cancer in surgical treatment toward molecular-guided surgery2017

    • Author(s)
      Oshima Yusuke、Koga Shigehiro、Watanabe Yuji
    • Organizer
      Photonics West2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] FIB-SEM で探る骨形成-コラーゲン細線維の集束化と骨細胞ネットワーク形成の関連について-2016

    • Author(s)
      上岡寛、橋本真奈、長岡紀幸、飯村忠浩、大嶋佑介、原徹
    • Organizer
      第43回日本臨床バイオメカニクス学会
    • Place of Presentation
      北海道立道民活動センター かでる2・7
    • Year and Date
      2016-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] 変形性関節症モデルマウスを用いた関節軟骨の変性過程のラマンスペクトル解析2016

    • Author(s)
      大嶋佑介、明比麻由、清松悠、三浦裕正
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] Changes in chemical composition of bone and cartilage matirix in animal disease models detected by Raman spectroscopy2016

    • Author(s)
      Yusuke Oshima, Mayu Akehi, Yasumitsu Ishimaru, Hiroshi Kiyomatsu, Yuuki Imai, Tadahiro Iimura, Hiromasa Miura
    • Organizer
      Japan-Taiwan Medical Spectroscopy International Symposium
    • Place of Presentation
      Awaji Yumebutai International Conference Center
    • Year and Date
      2016-12-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] ラマン分光法による骨・軟骨疾患モデルの基礎的検討と診断応用2016

    • Author(s)
      大嶋佑介、石丸泰光、明比麻由、清松悠、飯村忠浩、今井祐記、日野和典、三浦裕正
    • Organizer
      第43回日本臨床バイオメカニクス学会
    • Place of Presentation
      北海道立道民活動センター かでる2・7
    • Year and Date
      2016-10-08
    • Data Source
      KAKENHI-PROJECT-16H05912
  • [Presentation] In vivo imaging of spinal cord in contusion injury model mice by multi-photon microscopy2014

    • Author(s)
      Oshima Y, Horiuchi H, Ogata T, Hikita A, Miura H and Imamura T
    • Organizer
      Photonics West 2014, Biomedical Optics (BIOS 2014), Imaging, Manipulation, and Analysis of Biomeleules, Cells, and Tissues XII 8947-7
    • Place of Presentation
      San Francisco, California USA (口頭)
    • Data Source
      KAKENHI-PROJECT-24650297
  • [Presentation] Evaluation of osteoarthritis based on second harmonic generation (SHG) imaging2014

    • Author(s)
      清松悠、大嶋佑介、疋田温彦、三浦裕正、今村健志
    • Organizer
      第4回 Vivid Workshop
    • Place of Presentation
      金沢市
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] ラマン分光法を用いた骨代謝・骨形態計測2014

    • Author(s)
      大嶋佑介
    • Organizer
      第4回バイオラマン研究会,最先端光計測とライフサイエンスの近未来 -バイオ・ラマン2017-
    • Place of Presentation
      東北大学片平キャンパス片平さくらホール
    • Year and Date
      2014-05-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] In vivo imaging of spinal cord in contusion injury model mice by multi-photon microscopy2014

    • Author(s)
      Y. Oshima, H. Horiuchi, T. Ogata, A. Hikita, H. Miura, and T. Imamura
    • Organizer
      Photonics West 2014, Biomedical Optics (BIOS 2014)
    • Place of Presentation
      San Francisco, CA, USA
    • Data Source
      KAKENHI-PROJECT-24650297
  • [Presentation] Evaluation of cartilage based on second harmonic generation microscopy2014

    • Author(s)
      Hiroshi Kiyomatsu, Yusuke Oshima, Atsuhiko Hikita, Tadahiro Iimura, Takashi Saito, Tsuyoshi Miyazaki, Hiromasa Miura, Takeshi Imamura
    • Organizer
      American Society for Bone and Mineral Research Annual Meeting 2014
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] Evaluation of cartilage based on second harmonic generation microscopy2014

    • Author(s)
      H. Kiyomatsu, Y.Oshima, A.Hikita, T.Iimura, T.Saito, T.Miyazaki, H.Miura, T.Imamura
    • Organizer
      American Society for Bone and Mineral Research Annual Meeting 2014
    • Place of Presentation
      Houston, USA
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] Evaluation of osteoarthritis based on second harmonic generation (SHG) imaging2014

    • Author(s)
      清松悠、大嶋佑介、疋田温彦、三浦裕正、今村健志
    • Organizer
      第6回大学院専攻研究発表会
    • Place of Presentation
      東温市
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] Evaluation of osteoarthritis based on second harmonic generation (SHG) imaging2014

    • Author(s)
      清松悠、大嶋佑介、疋田温彦、三浦裕正、今村健志
    • Organizer
      第6回 大学院専攻研究発表会
    • Place of Presentation
      東温市
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] In vivo imaging of spinal cord in contusion injury model mice by multi-photon microscopy2014

    • Author(s)
      Y. Oshima, H. Horiuchi, T. Ogata, A. Hikita, H. Miura, and T. Imamura
    • Organizer
      Photonics West 2014, Biomedical Optics (BIOS 2014)
    • Place of Presentation
      San Francisco, CA, USA
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] Evaluation of osteoarthritis based on second harmonic generation (SHG) imaging2014

    • Author(s)
      清松悠、大嶋佑介、疋田温彦、三浦裕正、今村健志
    • Organizer
      第4回Vivid Workshop
    • Place of Presentation
      金沢市
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] Evaluation degeneration of articular cartilage in mice based on second harmonic generation microscopy2013

    • Author(s)
      Hiroshi Kiyomatsu, Yusuke Oshima, Atsuhiko Hikita, Hiromasa Miura, Takeshi Imamura
    • Organizer
      Conference on Laser Surgery and Medicine
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] In vivoイメージングのための非線形光学顕微鏡の開発と医療応用2013

    • Author(s)
      大嶋佑介,本蔵直樹,疋田温彦,今村健志
    • Organizer
      第39回レーザ顕微鏡研究会講演会
    • Place of Presentation
      埼玉県 理化学研究所
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650297
  • [Presentation] 非線形光学技術を用いた変形性関節症の評価法の確立2013

    • Author(s)
      清松悠、大嶋佑介、疋田温彦、三浦裕正、今村健志
    • Organizer
      Orthopedic Research Club 2013
    • Place of Presentation
      木更津市
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] ラマン分光法を用いたがん細胞の無染色イメージング技術の開発2013

    • Author(s)
      大嶋佑介,疋田温彦,今村健志
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      神奈川県 パシフィコ横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] In Vivo Imaging and Tissue Ablation for Spinal Cord Injury Model Mice Using Multiphoton Microscopy System with 1045 nm Femtosecond Fiber Laser2013

    • Author(s)
      Yusuke Oshima, Hideki Horiuchi, Tadanori Ogata, Atsuhiko Hikita, Hiromasa Miura, and Takeshi Imamura
    • Organizer
      Conference on Laser Surgery and Medicine 2013 (CLSM 2013)
    • Place of Presentation
      Yokohama JAPAN
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] Evaluation of osteoarthritis based on second harmonic generation microscopy2013

    • Author(s)
      Hiroshi Kiyomatsu, Yusuke Oshima, Atsuhiko Hikita, Hiromasa Miura, Takeshi Imamura
    • Organizer
      American Society for Bone and Mineral Research Annual Meeting 2013
    • Place of Presentation
      Baltimore, USA
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] 種々のバイオイメージング技術の構築について2013

    • Author(s)
      大嶋佑介
    • Organizer
      第11回医用分光学研究会
    • Place of Presentation
      福井県 三国観光ホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] Development of nonlinear optical imaging technique for medical applications by the new optical devises2013

    • Author(s)
      Yusuke Oshima, Takashi Katagiri, Yuji Matsuura, Atsuhiko Hikita and Takeshi Imamura
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      兵庫県 ポートピアホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650297
  • [Presentation] Evaluation of osteoarthritis based on SHG imaging2013

    • Author(s)
      Hiroshi Kiyomatsu.,Yusuke Oshima., Atsuhiko Hikita., Hiromasa Miura.,Takeshi Imamura.
    • Organizer
      TGF-β family Signal Network and Live Imaging
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] Probe-less optical imaging technique for medical applications based on Raman spectroscopy and nonlinear optics2013

    • Author(s)
      Yusuke Oshima, Atsuhiko. Hikita, Takeshi Imamura
    • Organizer
      TGF-b Family: Signal Network and Live Imaging
    • Place of Presentation
      愛媛県 大和屋本店
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] 種々のバイオイメージング技術の構築について2013

    • Author(s)
      大嶋佑介
    • Organizer
      第11回医用分光学研究会
    • Place of Presentation
      福井県 三国観光ホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650297
  • [Presentation] Development of nonlinear optical imaging technique for medical applications by the new optical devises2013

    • Author(s)
      Oshima Y, Katagiri T, Matsuura Y, Hikita A and Imamura T
    • Organizer
      第36回日本分子生物学会年会ワークショップ異分野連携が拓く新規光学デバイスを駆使したバイオイメージングと医療応用への展開」
    • Place of Presentation
      ポートピアホテル(兵庫県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650297
  • [Presentation] 種々のバイオイメージング技術の構築について2013

    • Author(s)
      大嶋佑介
    • Organizer
      第11回医用分光学研究会「診断画像構築と増感治療開発の基礎技術としての医用分光」
    • Place of Presentation
      三国観光ホテル(福井県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650297
  • [Presentation] Development of nonlinear optical imaging technique for medical applications by the new optical devises2013

    • Author(s)
      Yusuke Oshima, Takashi Katagiri, Yuji Matsuura, Atsuhiko Hikita and Takeshi Imamura
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      兵庫県 ポートピアホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] In vivoイメージングのための非線形光学顕微鏡の開発と医療応用2013

    • Author(s)
      大嶋佑介,本蔵直樹,疋田温彦,今村健志
    • Organizer
      第39回レーザ顕微鏡研究会講演会シンポジウム「新規光源を用いた顕微鏡」
    • Place of Presentation
      理化学研究所和光本所(埼玉県)
    • Year and Date
      2013-07-31
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650297
  • [Presentation] ラマン分光法・非線形光学イメージングによる骨基質の分子計測2013

    • Author(s)
      大嶋佑介,疋田温彦,今村健志
    • Organizer
      第33回日本骨形態計測学会
    • Place of Presentation
      静岡県 アクトシティ浜松
    • Invited
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] Evaluation of articular cartilage degeneration in mice based on second harmonic generation microscopy2013

    • Author(s)
      Hiroshi Kiyomatsu.,Yusuke Oshima., Atsuhiko Hikita., Hiromasa Miura.,Takeshi Imamura.
    • Organizer
      Conference on Laser Surgery and Medicine 2013
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] In vivoイメージングのための非線形光学顕微鏡の開発と医療応用2013

    • Author(s)
      大嶋佑介,本蔵直樹,疋田温彦,今村健志
    • Organizer
      第39回レーザ顕微鏡研究会講演会
    • Place of Presentation
      埼玉県 理化学研究所
    • Invited
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] Evaluation of osteoarthritis based on SHG imaging TGF-βfamily2013

    • Author(s)
      Hiroshi Kiyomatsu, Yusuke Oshima, Atsuhiko Hikita, Hiromasa Miura, Takeshi Imamura
    • Organizer
      Signal Network and Imaging Live
    • Place of Presentation
      Matsuyama
    • Data Source
      KAKENHI-PROJECT-24659680
  • [Presentation] Real time monitoring for differentiation of primary osteoblast culture by using Raman microscopy2013

    • Author(s)
      Yusuke Oshima, Atsuhiko Hikita, and Takeshi Imamura
    • Organizer
      ASBMR 2013 Annual Meeting
    • Place of Presentation
      Baltimore, MD, USA
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] Development of probe-less imaging techniques for translational research2012

    • Author(s)
      Yusuke Oshima, Naoki Honkura, Atsuhiko Hikita and Takeshi Imamura
    • Organizer
      第35回日本分子生物学会年会ワークショップ
    • Place of Presentation
      福岡マリンメツセ(福岡)(招待講演)
    • Year and Date
      2012-12-12
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] 生体の無染色イメージング技術開発と医学応用2012

    • Author(s)
      大嶋佑介, 今村健志
    • Organizer
      2012年・秋季 第73回応用物理学会学術講演会一般, ポスター)
    • Place of Presentation
      愛媛大学(愛媛県)
    • Year and Date
      2012-09-13
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] ラマン分光法の医学応用 : 生細胞計測, 装置開発から診断に向けて2012

    • Author(s)
      大嶋佑介, 橋本剛佑, 疋田温彦, 小杉浩司, 佐藤英俊, 野中茂紀, 今村健志
    • Organizer
      理化学研究所 第1回バイオラマン研究会, 最先端光計測とライフサイエンスの近未来 : バイオ・ラマン2017.
    • Place of Presentation
      理化学研究所(埼玉県)(招待講演)
    • Year and Date
      2012-05-19
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] in vivoイメージングのための顕微鏡製作と応用2012

    • Author(s)
      大嶋佑介
    • Organizer
      東京理科大学 第4回イメージングワークショップ
    • Place of Presentation
      東京理科大学(千葉県)(招待講演)
    • Year and Date
      2012-04-04
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] ハイスループットラマン分光イメージングシステムを用いた生体組織の網羅的解析2012

    • Author(s)
      大嶋佑介, 疋田温彦, 今村健志
    • Organizer
      理化学研究所 第2回バイオラマン研究会, 最先端光計測とライフサイエンスの近未来 : バイオ・ラマン2017
    • Place of Presentation
      理化学研究所(埼玉県)(招待講演)
    • Year and Date
      2012-10-28
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] ラマン分光法による骨粗鬆症ラット骨基質の分子計測

    • Author(s)
      大嶋佑介、飯村忠浩、齋藤卓、今村健志
    • Organizer
      第35回レーザー学会学術講演会
    • Place of Presentation
      東海大学高輪校舎
    • Year and Date
      2015-01-11 – 2015-01-12
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] Changes in chemical composition of bone matrix in ovariectomized (OVX) rats detected by Raman spectroscopy and multivariate analysis

    • Author(s)
      Yusuke Oshima, Tadahiro Iimura, Takashi Saitou, Takeshi Imamura
    • Organizer
      Photonics West 2015 (BiOS2015)
    • Place of Presentation
      San Francisco USA
    • Year and Date
      2015-02-07 – 2015-02-12
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] Development of wide-field of view 2p-excited light-sheet microscopy

    • Author(s)
      Yusuke Oshima, Atsushi Maruyama, Shigenori Nonaka, Takeshi Imamura, Kiyoshi Naruse
    • Organizer
      International Symposium on Multi-dimensional Fluorescence Live Imaging of Cellular Functions and Molecular Activities
    • Place of Presentation
      Kyoto International Conference Center
    • Year and Date
      2015-02-26 – 2015-02-28
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] Raman spectroscopic study for osteoporosis in ovariectomized (OVX) rats

    • Author(s)
      Yusuke Oshima, Tadahiro Iimura, Atsuhiko Hikita, Takeshi Imamura
    • Organizer
      Biomedical Imaging and Sensing Conference ’14 (BISC’14)
    • Place of Presentation
      Yokohama
    • Year and Date
      2014-04-22 – 2014-04-24
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] , “Changes in chemical composition of bone matrix in osteoporosis detected by Raman spectroscopy and multivariate analysis

    • Author(s)
      Yusuke Oshima
    • Organizer
      1st Raman Bio-sensing Seminar
    • Place of Presentation
      Kwansei Gakuin University
    • Year and Date
      2015-01-19 – 2015-01-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] ラマン分光・イメージング技術の開発と骨代謝研究への応用

    • Author(s)
      大嶋佑介, 飯村忠浩, 疋田温彦, 今村健志
    • Organizer
      第32回日本骨代謝学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-07-24 – 2014-07-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] ラマン分光法および多変量解析による骨粗鬆症ラットの骨基質の解析

    • Author(s)
      大嶋佑介、飯村忠浩、齋藤卓、今村健志
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24680060
  • [Presentation] ラマン分光分析を基盤とした骨質計測技術の開発

    • Author(s)
      大嶋佑介, 飯村忠浩, 疋田温彦, 今村健志
    • Organizer
      第34回日本骨形態計測学会シンポジウム
    • Place of Presentation
      さっぽろ芸文館
    • Year and Date
      2014-06-12 – 2014-06-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-24680060
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