Motomura Yasutaka 本村泰隆

Researcher Number	10587794
Other IDs	https://orcid.org/0000-0003-1088-9985
Affiliation (Current)	2025: 東京理科大学, 研究推進機構生命医科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2024: 東京理科大学, 研究推進機構生命医科学研究所, 准教授 2022 – 2023: 大阪大学, 大学院医学系研究科, 准教授 2018 – 2021: 大阪大学, 医学系研究科, 准教授 2015 – 2016: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / Immunology
Keywords	Principal Investigator 自然リンパ球 / 自然免疫 / ILC2 / アレルギー / 炎症記憶 / 収束機構 / サイトカインデコイ / モデルマウス / 肺線維症 / IL-4 … More / IgE / 微小環境ニッチ / 好酸球集積 / ニッチ / NH細胞 Less

2型自然リンパ球による炎症記憶を介したアレルギー炎症慢性化機序の解明Principal Investigator
- Principal Investigator
  
  本村泰隆
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tokyo University of Science
Mechanism of cytokine decoy-mediated convergence of inflammatory responses by innate lymphoid cellsPrincipal Investigator
- Principal Investigator
  
  Motomura Yasutaka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Osaka University
Mechanism of IL-4-mediated immune regulation by group 2 innate lymphoid cellsPrincipal Investigator
- Principal Investigator
  
  Motomura Yasutaka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Osaka University
肺線維症を自然発症するマウスを用いた細胞ネットワーク解析Principal Investigator
- Principal Investigator
  
  本村泰隆
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Osaka University
Identification of niches of natural helper cells in non-lymphoid tissuesPrincipal Investigator
- Principal Investigator
  
  Motomura Yasutaka
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] 炎症と免疫2015
- Author(s)
  本村　泰隆
- Publisher
  株式会社　先端医学社
- Data Source
  KAKENHI-PROJECT-15K15158
[Journal Article] Time-dependent cell-state selection identifies transiently expressed genes regulating ILC2 activation2023
- Author(s)
  Tanaka Yumiko、Yamagishi Mai、Motomura Yasutaka、Kamatani Takashi、Oguchi Yusuke、Suzuki Nobutake、Kiniwa Tsuyoshi、Kabata Hiroki、Irie Misato、Tsunoda Tatsuhiko、Miya Fuyuki、Goda Keisuke、Ohara Osamu、Funatsu Takashi、Fukunaga Koichi、Moro Kazuyo、Uemura Sotaro、Shirasaki Yoshitaka
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 915-915
- DOI
  10.1038/s42003-023-05297-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18232, KAKENHI-PROJECT-21H02750, KAKENHI-PROJECT-23K24342
[Journal Article] Activation of ILC2s through constitutive IFNγ signaling reduction leads to spontaneous pulmonary fibrosis2023
- Author(s)
  Natsuko Otaki, Yasutaka Motomura, Tommy Terooatea, S Thomas Kelly, Miho Mochizuki, Natsuki Takeno, Shigeo Koyasu, Miu Tamamitsu, Fuminori Sugihara, Junichi Kikuta, Hideya Kitamura, Yoshiki Shiraishi, Jun Miyanohara, Yuji Nagano, Yuji Saita, Takashi Ogura, Koichiro Asano, Aki Minoda, Kazuyo Moro
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 8120-8120
- DOI
  10.1038/s41467-023-43336-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02750
[Journal Article] ILCs and Allergy2022
- Author(s)
  Kabata Hiroki、Motomura Yasutaka、Kiniwa Tsuyoshi、Kobayashi Tetsuro、Moro Kazuyo
- Journal Title
  
  Advances in Experimental Medicine and Biology
  
  Volume: 6 Pages: 75-95
- DOI
  10.1007/978-981-16-8387-9_6
- ISBN
  9789811683862, 9789811683879
- Data Source
  KAKENHI-PROJECT-21H02750
[Journal Article] The discovery of group 2 innate lymphoid cells has changed the concept of type 2 immune diseases2021
- Author(s)
  Kobayashi Tetsuro、Motomura Yasutaka、Moro Kazuyo
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 12 Pages: 705-709
- DOI
  10.1093/intimm/dxab063
- Open Access
- Data Source
  KAKENHI-PROJECT-18H05286, KAKENHI-PROJECT-21H02750, KAKENHI-PROJECT-21F21115
[Journal Article] Notch signaling enhances FceRI-mediated cytokine production by mast cells through direct and indirect mechanisms2015
- Author(s)
  Nakano, N., Nishiyama, C., Yagita, H., Hara, M., Motomura, Y., Kubo, M., Okumura, K., and Ogawa, H
- Journal Title
  
  J. Immunol
  
  Volume: 194(9) Issue: 9 Pages: 4535-44
- DOI
  10.4049/jimmunol.1301850
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249058, KAKENHI-PROJECT-24591667, KAKENHI-PROJECT-15K09784, KAKENHI-PROJECT-15K15158, KAKENHI-PUBLICLY-15H01162, KAKENHI-PUBLICLY-15H01267, KAKENHI-PROJECT-26293087
[Presentation] Cytokine-induced IgE production from B1 cells exacerbates allergic inflammation2024
- Author(s)
  Yasutaka Motomura
- Organizer
  第52回日本免疫学術集会
- Data Source
  KAKENHI-PROJECT-21H02750
[Presentation] アレルギー病態における抗原非特異的IgEの役割2023
- Author(s)
  本村泰隆
- Organizer
  第72回日本アレルギー学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02750
[Presentation] ２型自然リンパ球による２型炎症2022
- Author(s)
  本村　泰隆
- Organizer
  第5回眼科アレルギー学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02750
[Presentation] 気管支喘息病態を引き起こすサイトカインネットワーク2022
- Author(s)
  本村　泰隆
- Organizer
  第71回日本アレルギー学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02750
[Presentation] 2型自然リンパ球とアレルギー疾患の難治化2022
- Author(s)
  本村　泰隆
- Organizer
  第7回日本アレルギー学会近畿地方会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02750
[Presentation] Group 2 innate lymphoid cells exacerbate allergic inflammation via an innate amplification circuit2021
- Author(s)
  Yasutaka Motomura
- Organizer
  The 27th International Symposium on Molecular Cell Biology of Macrophages (MMCB2020+1)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02750
[Presentation] Type 2炎症におけるILC2の新たな役割2021
- Author(s)
  本村　泰隆
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02750
[Presentation] ILC2とアレルギー2020
- Author(s)
  本村　泰隆
- Organizer
  第4回日本アレルギー学会地方会近畿支部
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] 免疫機構から見たアレルギー病態におけるIL-4/IL-13の役割2020
- Author(s)
  本村　泰隆
- Organizer
  銀杏 Allergy Basic Conference
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] Group 2 Innate lymphoid cells regulates the susceptibility to allergic inflammation via IL-4-dependent innate amplification circuit2019
- Author(s)
  Yasutaka Motomura
- Organizer
  17th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] アレルギー性疾患におけるGroup 2 innate lymphoid cell (ILC2)の役割2019
- Author(s)
  本村　泰隆
- Organizer
  第83回臨床アレルギー研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] Group 2 innate lymphoid cells regulate allergic susceptibility2019
- Author(s)
  Yasutaka Motomura
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] Type2炎症におけるIL-4/IL-13の新たな役割2019
- Author(s)
  本村　泰隆
- Organizer
  Hanshin Type 2 Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] 自然リンパ球と喘息・間質性肺炎‐臨床応用への可能性‐2019
- Author(s)
  本村　泰隆
- Organizer
  Scientific Exchange Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] ２型自然リンパ球によるアレルギー体質形成機構2019
- Author(s)
  本村　泰隆
- Organizer
  第20回京阪神小児・成人アレルギーフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] Group2 innate lymphoid cells regulate susceptibility to allergic lung inflammation via an innate amplification circuit.2018
- Author(s)
  Yasutaka Motomura, Shigeo Koyasu, Kazuyo Moro
- Organizer
  The 3rd International Conference on Innate Lymphoid Cells (ILC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] ILC2 regulate susceptibility to allergic lung inflammation via an innate amplification circuit driven by IL-42018
- Author(s)
  本村泰隆、小安重夫、茂呂和世
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] The role of group 2 innate lymphoid cells in antigen non-specific allergic disorders2018
- Author(s)
  本村泰隆
- Organizer
  第58回日本呼吸器学会学術講演会　呼吸器領域若手グローバル研究者シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] 2型自然リンパ球による新しいアレルギー発症メカニズム2018
- Author(s)
  本村泰隆
- Organizer
  第14回皮膚免疫疾患研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] 2型自然リンパ球による抗原に依存しないアレルギー病態増悪機構2018
- Author(s)
  本村泰隆、小安重夫、茂呂和世
- Organizer
  第46回日本臨床免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] 2型自然リンパ球による抗原非特異的アレルギー増悪機構の解明2018
- Author(s)
  本村泰隆
- Organizer
  第83回日本インターフェロン・サイトカイン学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07187
[Presentation] Role of Group 2 innate lymphoid cells in chronic allergic disorders2017
- Author(s)
  Yasutaka Motomura、Shigeo Koyasu、Kazuyo Moro
- Organizer
  The 19th Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  武田薬品研修所（大阪府吹田市）
- Year and Date
  2017-01-20
- Data Source
  KAKENHI-PROJECT-15K15158
[Presentation] Regulation of IL-4 production in Group2 innate lymphoid cells2017
- Author(s)
  Yasutaka Motomura、Shigeo Koyasu、Kazuyo Moro
- Organizer
  15th Cytokines & Inflammation Conference
- Place of Presentation
  San Diego, USA
- Year and Date
  2017-02-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15158
[Presentation] Regulation of IL-4 production in Group2 innate lymphoid cells2017
- Author(s)
  Yasutaka Motomura、Shigeo Koyasu、Kazuyo Moro
- Organizer
  7th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  京都大学芝蘭会館（京都府京都市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15K15158
[Presentation] ILC2におけるサイトカイン遺伝子の発現制御2016
- Author(s)
  本村泰隆、小安重夫、茂呂和世
- Organizer
  第26回Kyoto T Cell Conference
- Place of Presentation
  延暦寺会館（滋賀県大津市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-15K15158
[Presentation] Regulation of IL-4 production in Group2 innate lymphoid cells2016
- Author(s)
  Yasutaka Motomura、Shigeo Koyasu、Kazuyo Moro
- Organizer
  Innate lymphoid cells - 2016
- Place of Presentation
  Berlin, Germany
- Year and Date
  2016-12-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15158
[Presentation] グループ2自然リンパ球におけるIL-4産生機構2016
- Author(s)
  本村泰隆、小安重夫、茂呂和世
- Organizer
  第3回六甲医学研究会
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2016-10-28
- Data Source
  KAKENHI-PROJECT-15K15158
[Presentation] Regulation of IL-4 production in Group2 innate lymphoid cells2016
- Author(s)
  Yasutaka Motomura、Shigeo Koyasu、Kazuyo Moro
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター・ラグナガーデンホテル（沖縄県宜野湾市）
- Year and Date
  2016-12-06
- Data Source
  KAKENHI-PROJECT-15K15158
[Presentation] ILC2におけるIL-4産生機序の解明2016
- Author(s)
  本村泰隆、小安重夫、茂呂和世
- Organizer
  免疫四次元空間ダイナミクス　第5回班会議・第8回総括班会議・第4回サマースクール
- Place of Presentation
  徳島大学（徳島県徳島市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K15158
[Presentation] グループ2自然リンパ球によるIL-4を介した免疫応答の制御機構2016
- Author(s)
  本村泰隆、小安重夫、茂呂和世
- Organizer
  老化シンポジウム
- Place of Presentation
  明治安田生命ビルMY PLAZAホール（東京都千代田区）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K15158

1. MORO Kazuyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 久保允人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 上村想太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Motomura Yasutaka 本村 泰隆

Research Projects

Research Products

Co-Researchers

2型自然リンパ球による炎症記憶を介したアレルギー炎症慢性化機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of cytokine decoy-mediated convergence of inflammatory responses by innate lymphoid cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of IL-4-mediated immune regulation by group 2 innate lymphoid cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺線維症を自然発症するマウスを用いた細胞ネットワーク解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Identification of niches of natural helper cells in non-lymphoid tissuesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 炎症と免疫2015

Author(s)

Publisher

Data Source

[Journal Article] Time-dependent cell-state selection identifies transiently expressed genes regulating ILC2 activation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of ILC2s through constitutive IFNγ signaling reduction leads to spontaneous pulmonary fibrosis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ILCs and Allergy2022

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] The discovery of group 2 innate lymphoid cells has changed the concept of type 2 immune diseases2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Notch signaling enhances FceRI-mediated cytokine production by mast cells through direct and indirect mechanisms2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Cytokine-induced IgE production from B1 cells exacerbates allergic inflammation2024

Author(s)

Organizer

Data Source

[Presentation] アレルギー病態における抗原非特異的IgEの役割2023

Author(s)

Organizer

Data Source

[Presentation] ２型自然リンパ球による２型炎症2022

Author(s)

Organizer

Data Source

[Presentation] 気管支喘息病態を引き起こすサイトカインネットワーク2022

Author(s)

Organizer

Data Source

[Presentation] 2型自然リンパ球とアレルギー疾患の難治化2022

Motomura Yasutaka 本村泰隆