HIRASHIMA Kotaro 平島浩太郎

Researcher Number	10594468
Other IDs	https://orcid.org/0000-0002-3703-076X
Affiliation (based on the past Project Information) *help	2011 – 2015: 熊本大学, 医学部附属病院, 非常勤診療医師 2012: 熊本大学, 医学部附属病院, その他
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator General surgery / Digestive surgery
Keywords	Principal Investigator mTOR阻害剤 / PI3K/AKT / cell cycle / 食道扁平上皮癌 / RAD001 / mTOR / hedgehog / Gli1 / Hedgehogシグナル / 抗癌剤感受性 … More / アポトーシス / 食道癌 / 免疫染色 / proliferation / apoptosis / cell growth / PI3K/Akt … More Except Principal Investigator microRNA / miRNA / replacement therapy / 食道癌 / mTOR / 耐性 / 白金製剤 / 胃癌 / 白金製剤耐性 / 塩基修復遺伝子 Less

Elucidation of interaction between the expression of mTOR and the hedgehog pathway on esophageal squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  HIRASHIMA Kotaro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Regulation of Mammalian Target of Rapamycin (mTOR) Signaling by MicroRNA in esophageal cancer
- Principal Investigator
  
  KINOSHITA Kouichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kumamoto University
The identification of miR-gene pathway regulating the sensitivity of platinum agentsfor gastric cancer and its clinical applicatio
- Principal Investigator
  
  BABA Hideo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Can mTOR become target of the molecular target therapy in esophagus squamous cell carcinoma?Principal Investigator
- Principal Investigator
  
  HIRASHIMA Kotaro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University

All 2015 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] Carcinoembryonic Antigen Half-life Is an Early Predictor of Therapeutic Effects in Induction Chemotherapy for Liver Metastases from Colorectal Cancer2014
- Author(s)
  Nagai Y, Beppu T, Sakamoto Y, Miyamoto Y, Hayashi H, Nitta H, Imai K, Masuda T, Okabe H, Hirashima K, Imamura Y, Baba Y, Chikamoto A, Baba H
- Journal Title
  
  Anticancer Res
  
  Volume: 34(10) Pages: 5529-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861204
[Journal Article] Intra-abdominal mucinous adenocarcinoma of urachal origin: report of a case2014
- Author(s)
  Hirashima K, Uchino R, Kume S, Iyama K, Honda Y, Asato T, Baba H
- Journal Title
  
  Surg Today
  
  Volume: 44(6) Issue: 6 Pages: 1156-60
- DOI
  10.1007/s00595-013-0620-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861204
[Journal Article] Prognostic significance of the modified Glasgow prognostic score in elderly patients with gastric cancer2014
- Author(s)
  Hirashima K, Watanabe M, Shigaki H, Imamura Y, Ida S, Iwatsuki M, Ishimoto T, Iwagami S, Baba Y, Baba H
- Journal Title
  
  J Gastroenterol
  
  Volume: 49(6) Issue: 6 Pages: 1040-6
- DOI
  10.1007/s00535-013-0855-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591948, KAKENHI-PROJECT-25861204
[Journal Article] Prognostic significance of the modified Glasgow prognostic score in elderly patients with gastric cancer.2014
- Author(s)
  Hirashima K, Watanabe M, Shigaki H, Imamura Y, Ida S, Iwatsuki M, Ishimoto T, Iwagami S, Baba Y, Baba H.
- Journal Title
  
  J Gastroenterol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861204
[Journal Article] Intra-abdominal mucinous adenocarcinoma of urachal origin: report of acase.2014
- Author(s)
  Hirashima K, Uchino R, Kume S, Iyama KI, Honda Y, Asato T, Baba H.
- Journal Title
  
  Surg Today
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861204
[Journal Article] Small molecule agonists of PPAR-γ exert therapeutic effects in esophageal cancer.2014
- Author(s)
  Sawayama H, Ishimoto T, Watanabe M, Yoshida N, Sugihara H, Kurashige J, Hirashima K, Iwatsuki M, Baba Y, Oki E, Morita M, Shiose Y, Baba H.
- Journal Title
  
  Cancer Res
  
  Volume: 74 Pages: 575-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861204
[Journal Article] Differential expression of basement membrane type IV collagen α2 and α6 chains as a prognostic factor in patients with extrahepatic bile duct carcinoma2013
- Author(s)
  Hirashima K, Iyama K, Baba Y, Honda Y, Sado Y, Ninomiya Y, Watanabe M, Takamori H, Beppu T, Baba H
- Journal Title
  
  J Surg Oncol
  
  Volume: 107(4) Issue: 4 Pages: 402-7
- DOI
  10.1002/jso.23225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390348, KAKENHI-PROJECT-23592164, KAKENHI-PROJECT-23791551, KAKENHI-PROJECT-24659590
[Journal Article] Aberrant activation of the mTOR pathway and anti-tumour effect of everolimus on oesophageal squamous cell carcinoma2012
- Author(s)
  Hirashima K, Baba Y, Watanabe M,Karashima RI, Sato N, Imamura Y, NagaiY, Hayashi N, Iyama KI, Baba H
- Journal Title
  
  Br J Cancer
  
  Volume: 106 Pages: 876-82
- NAID
  120005148224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791551
[Journal Article] 膵頭部結核性リンパ節炎の 1 例2012
- Author(s)
  平島浩太郎、沖野哲也、田上弘文、木村有、小澄敬祐、松川哲也、八木泰志
- Journal Title
  
  日臨外会誌
  
  Volume: 73 Pages: 2353-2356
- NAID
  10031123818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791551
[Journal Article] Aberrant activation of the mTOR pathway and anti-tumour effect of everolimus on oesophageal squamous cell carcinoma2012
- Author(s)
  K.Hirashima, et al.
- Journal Title
  
  Brithish journal of cancer
  
  Volume: 106 Issue: 5 Pages: 876-882
- DOI
  10.1038/bjc.2012.36
- NAID
  120005148224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791551, KAKENHI-PROJECT-24591911
[Journal Article] Lymphatic vessel invasion detected by the D2-40 monoclonal antibody is an independent prognostic factor in node-negative esophageal squamous cell carcinoma2012
- Author(s)
  Imamura Y, Watanabe M, Nagai Y, BabaY, Hirashima K, Karashima R, IwatsukiM, Yoshida N, Kinoshita K, KurashigeJ, Iyama K, Baba H
- Journal Title
  
  J Surg Oncol
  
  Volume: 105 Issue: 3 Pages: 277-83
- DOI
  10.1002/jso.22079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791551
[Journal Article] Usefulness of　transcription-reverse transcription concerted reaction method for detecting circulating tumor cells in patients with colorectal cancer.2012
- Author(s)
  佐藤伸隆
- Journal Title
  
  Annals　of　Surgical Oncology
  
  Volume: 19 Issue: 6 Pages: 2060-5
- DOI
  10.1245/s10434-011-1889-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591965, KAKENHI-PROJECT-23591966, KAKENHI-PROJECT-23791551
[Journal Article] 第5章　消化器内科・外科　第1節「食道癌」　第2節「胃癌」2011
- Author(s)
  29.馬場祥史、渡邊雅之、岩槻政晃、石本崇胤、平島浩太郎、岩上志朗、長井洋平、辛島龍一、木下浩一、蔵重淳二、馬場秀夫
- Journal Title
  
  治療/診断技術のニーズとシーズ評価集
  
  Volume: なし Pages: 63-72
- Data Source
  KAKENHI-PROJECT-23791551
[Journal Article] Induction chemotherapy with docetaxel/cisplatin/5-fuorouracil for patients with node-positive esophageal cancer2011
- Author(s)
  Watanabe M, Nagai Y, Kinoshita K, Saito S, Kurashige J, Karashima R, Hirashima K, Sato N, Imamura Y, Hiyoshi Y, Baba Y, Iwagami S, Miyamoto Y, Iwatsuki M, Hayashi N, Baba H
- Journal Title
  
  Digestion
  
  Volume: 83 Issue: 3 Pages: 146-152
- DOI
  10.1159/000321797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591704, KAKENHI-PROJECT-23791551
[Presentation] 高齢者に対する胃癌手術の安全性の検討2015
- Author(s)
  平島浩太郎、小杉伸一、石川卓　他
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  アクトシティ浜松（鳥取県）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-25861204
[Presentation] E-PASS scoring systemによる胃切除術についての検討2015
- Author(s)
  平島浩太郎、石川卓、小杉伸一　他
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25861204
[Presentation] 高齢者胃癌における GlasgowPrognostic Score(GPS)の検討2012
- Author(s)
  平島浩太郎、渡邊雅之、藏重淳二、木下浩一、斉藤誠哉、井田智、石本崇胤、長井洋平、岩槻政晃、岩上志朗、馬場祥史、宮本裕士、別府透、馬場秀夫
- Organizer
  第112回日本外科学会定期学術総会
- Place of Presentation
  千葉県幕張メッセ国際展示場
- Year and Date
  2012-04-12
- Data Source
  KAKENHI-PROJECT-23791551
[Presentation] 高齢者胃癌患者における GlasgowPrognistic Score(GPS)の検討2012
- Author(s)
  平島浩太郎、渡邊雅之、蔵重淳二、木下浩一、齋藤誠哉、井田智、石本崇胤、長井洋平、岩槻政晃、岩上志朗、馬場祥史、宮本裕士、別府透、馬場秀夫
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉県幕張メッセ国際会議場
- Year and Date
  2012-04-14
- Data Source
  KAKENHI-PROJECT-23659656
[Presentation] 食道扁平上皮癌におけるmTOR阻害薬（RAD001）の臨床応用に向けた基礎的検討 / The anti-tumor effect of everolimus（RAD001）in esophageal squamous cell carcinoma2011
- Author(s)
  平島浩太郎
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  紙上発表
- Data Source
  KAKENHI-PROJECT-23791551
[Presentation] 食道扁平上皮癌における mTOR 阻害薬(RAD001)の抗腫瘍効果の検討2011
- Author(s)
  平島浩太郎、馬場祥史、渡邊雅之
- Organizer
  第111回日本外科学会定期学術総会
- Place of Presentation
  震災のため紙上開催
- Data Source
  KAKENHI-PROJECT-23791551
[Presentation] 局所進行食道癌に対するsalvage手術の検討2011
- Author(s)
  平島浩太郎
- Organizer
  第66回日本消化器外科学会総会
- Place of Presentation
  名古屋　名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23791551
[Presentation] 胃癌における microRNA-200b による癌浸潤転移の制御機構2011
- Author(s)
  藏重淳二、渡邊雅之、木下浩一、齋藤誠哉、佐藤伸隆、辛島龍一、平島浩太郎、日吉幸晴、岩槻政晃、蒲原英伸、林尚子、馬場秀夫
- Organizer
  第111回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23659656

1. BABA Hideo (20240905)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. WATANABE Masayuki (80254639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. BABA Yoshifumi (20599708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. KINOSHITA Kouichi (10507792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ISHIMOTO Takatsugu (00594889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HAYASHI Naoko (20452899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. IWATSUKI Masaaki (50452777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 二宮善文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 岩上志朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIRASHIMA Kotaro 平島 浩太郎

Research Projects

Research Products

Co-Researchers

Elucidation of interaction between the expression of mTOR and the hedgehog pathway on esophageal squamous cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of Mammalian Target of Rapamycin (mTOR) Signaling by MicroRNA in esophageal cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The identification of miR-gene pathway regulating the sensitivity of platinum agentsfor gastric cancer and its clinical applicatio

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Can mTOR become target of the molecular target therapy in esophagus squamous cell carcinoma?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Carcinoembryonic Antigen Half-life Is an Early Predictor of Therapeutic Effects in Induction Chemotherapy for Liver Metastases from Colorectal Cancer2014

Author(s)

Journal Title

Data Source

[Journal Article] Intra-abdominal mucinous adenocarcinoma of urachal origin: report of a case2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic significance of the modified Glasgow prognostic score in elderly patients with gastric cancer2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic significance of the modified Glasgow prognostic score in elderly patients with gastric cancer.2014

Author(s)

Journal Title

Data Source

[Journal Article] Intra-abdominal mucinous adenocarcinoma of urachal origin: report of acase.2014

Author(s)

Journal Title

Data Source

[Journal Article] Small molecule agonists of PPAR-γ exert therapeutic effects in esophageal cancer.2014

Author(s)

Journal Title

Data Source

[Journal Article] Differential expression of basement membrane type IV collagen α2 and α6 chains as a prognostic factor in patients with extrahepatic bile duct carcinoma2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aberrant activation of the mTOR pathway and anti-tumour effect of everolimus on oesophageal squamous cell carcinoma2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 膵頭部結核性リンパ節炎の 1 例2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Aberrant activation of the mTOR pathway and anti-tumour effect of everolimus on oesophageal squamous cell carcinoma2012

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Lymphatic vessel invasion detected by the D2-40 monoclonal antibody is an independent prognostic factor in node-negative esophageal squamous cell carcinoma2012

Author(s)

Journal Title

DOI

Data Source

HIRASHIMA Kotaro 平島浩太郎

[Journal Article] Usefulness of　transcription-reverse transcription concerted reaction method for detecting circulating tumor cells in patients with colorectal cancer.2012

[Journal Article] 第5章　消化器内科・外科　第1節「食道癌」　第2節「胃癌」2011