Nakagawa Shigeki 中川茂樹

… Alternative Names

NAKAGAWA Shigeki 中川茂樹

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Researcher Number	10594872
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(医), 特定研究員
Affiliation (based on the past Project Information) *help	2021 – 2024: 熊本大学, 病院, 特任助教 2019 – 2020: 熊本大学, 病院, 非常勤診療医師 2018: 熊本大学, 医学部附属病院, 寄附講座教員 2018: 熊本大学, 医学部附属病院, 特任助教 2018: 熊本大学, 医学部附属病院, 非常勤診療医師 … More 2017: 熊本大学, 医学部附属病院, 医員 2016: 熊本大学, 医学部附属病院, 寄附講座教員 2016: 熊本大学, 医学部附属病院, 特任助教 2015: 熊本大学, 医学部附属病院, 非常勤診療医師 Less
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Digestive surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55010:General surgery and pediatric surgery-related / General surgery
Keywords	Principal Investigator バイオマーカー / 予後 / Molecular gene signature / 膵癌 / gene signature / 治療標的 / ARDHGEF2 / 化学療法 / ARHGEF2 / Cofilin-1 … More / 癌免疫 / 腫瘍免疫 / 抗癌剤 / 細胞周期 / DKK2 / 胆管癌 / 薬剤感受性予測因子 / 酸化ストレス / 脂肪酸代謝 / NAFLD/NASH肝細胞癌 / 脂肪肝 / 癌代謝 / NASH / NAFLD / TM6SF2 / 遺伝子発現 / 非アルコール性脂肪肝 / 肝細胞癌 … More Except Principal Investigator 膵癌 / 癌幹細胞 / Hippo pathway / 肝細胞癌 / バイオマーカー / TNF-α / 腫瘍免疫 / PD-L1 / 腫瘍微小環境 / マクロファージ / 抗がん剤抵抗性 / Taz / Yap / TAZ / YAP / 消化器癌 / マイクロRNA / micro RNA / 細胞周期 / 胆管癌 / EZH2 / 肝内胆管癌 / 個別化治療 / リキッドバイオプシー / 腹膜播種 / 抗腫瘍免疫 / 免疫細胞分離 / がん微小環境 / 制御性T細胞 / CD8陽性Tリンパ球 / 腫瘍関連マクロファージ / 腫瘍関連好中球 / CXCL12-CXCR4 axis / CXCL12-CXCR4 signaling / スタチン / signaling / CXCL12-CXCR4 / CAF / 癌微小環境 / 癌 / 肝炎ウイルス / Copy数 / LINE-1 / DNAメチル化 / エピジェネティクス / Amplification / レトロトランスポゾン / 非肝炎ウイルス性肝細胞癌 / Vivo / 予後不良 / vivo / 免疫化学組織染色 / cDNAマイクロアレイ / 転移 / CXCL12 / 免疫学的癌微小環境 / サルコペニア / 腫瘍浸潤マクロファージ / PD-1 / 免疫チェックポイント / 腫瘍免疫学 / TSP-1 / 肝中心静脈閉塞症 / bevacizumab / Thrombospondin-1（TSP-1） / oxaliplatin / 肝類洞閉塞症候群 / 大腸癌肝転移 / Hippo-pathway / Zeste Homolog 2 / Cancer progression / HCC / Angiogenesis / アポトーシス / DZNep / Notch1 / 細胞増殖 / 血管新生 / VASH1 Less

Gene signatureによる膵癌化学療法の治療効果予測及び新規治療標的の検証Principal Investigator
- Principal Investigator
  
  中川茂樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kumamoto University
がん幹細胞能維持と免疫回避微小環境を誘導する機構解明と新規治療法の開発
- Principal Investigator
  
  林洋光
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
リキッドバイオプシーを用いた膵癌個別化治療のための腹膜播種予測miRNAパネルの開発
- Principal Investigator
  
  山村謙介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kumamoto University
肝細胞癌切除新鮮組織からの細胞分離による腫瘍免疫細胞クロストークの解明
- Principal Investigator
  
  遊佐俊彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Molecular gene signature and molecular targeted therapy for pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  Nakagawa Shigeki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
The significance and the mechanism of PD-L1 expression in the tumor microenvironment for novel therapeutic agents
- Principal Investigator
  
  Tsukamoto Masayo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University
Interaction between Hippo pathway and cancer microenvironment in pancreatic cancer.
- Principal Investigator
  
  Higashi Takaaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
LINE-1methylation in nonhepatitis virus hepatocellular carcinoma
- Principal Investigator
  
  Beppu Toru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kumamoto University
Biological roles of dysregulated Hippo pathway on cancer stem like function during the tumor progression of gastroenterological cancers
- Principal Investigator
  
  Hayashi Hiromitsu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
DKK2 targeting therapy for cholangiocarcinoma found by exhausted gene analysis.Principal Investigator
- Principal Investigator
  
  NAKAGAWA Shigeki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
The mechanism of promoting liver metastasis caused by CXCL 12 and fundamental research for innovative therapeutic development in intrahepatic cholangiocarcinoma
- Principal Investigator
  
  MASUDA Tosirou
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Sarcopenia and immunological tumor microenvironment
- Principal Investigator
  
  Imai Katsunori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Biological significance of Hippo-pathway in gastrointestinal cancer
- Principal Investigator
  
  HAYASHI Hiromitsu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Functional analysis of the cancer development from fatty acid metabolism and oxidative phosphorylation of HCC based on NAFLD/NASHPrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Shigeki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Drug screening for cholangiocarcinoma targeting the epigenetical mechanism of cancer progression
- Principal Investigator
  
  CHIKAMOTO Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Clarification the molecular mechanism of chemotherapy-related sinusoidal obstructive syndrome and the study for efficacy of anti–vascular endothelial growth factor therapy.
- Principal Investigator
  
  KUROKI Hideyuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
The identification and functional analysis of micro RNA via polycomb proteins in HCC progression.
- Principal Investigator
  
  MASUDA Toshiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Kumamoto University

All 2023 2021 2020 2019 2018 2017 2016 2015 2013

All Journal Article Presentation

[Journal Article] Hyperglycaemia induces metabolic reprogramming into a glycolytic phenotype and promotes epithelial-mesenchymal transitions via YAP/TAZ-Hedgehog signalling axis in pancreatic cancer.2023
- Author(s)
  Liu Z,
- Journal Title
  
  Br J Cancer.
  
  Volume: 128(5) Issue: 5 Pages: 844-856
- DOI
  10.1038/s41416-022-02106-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08757, KAKENHI-PROJECT-20K09059, KAKENHI-PROJECT-20K09081, KAKENHI-PROJECT-21K15534
[Journal Article] Four gene intrahepatic metastasis-risk signature predicts hepatocellular carcinoma malignant potential and early recurrence from intrahepatic metastasis2021
- Author(s)
  Nakagawa Shigeki、Yamashita Yo-ichi、Umezaki Naoki、Yamao Takanobu、Kaida Takayoshi、Hiyoshi Yukiharu、Mima Kosuke、Okabe Hirohisa、Hayashi Hiromitsu、Imai Katsunori、Chikamoto Akira、Baba Hideo
- Journal Title
  
  Surgery
  
  Volume: 169 Issue: 4 Pages: 903-910
- DOI
  10.1016/j.surg.2020.09.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18124
[Journal Article] High ARHGEF2 (GEF-H1) Expression is Associated with Poor Prognosis Via Cell Cycle Regulation in Patients with Pancreatic Cancer2021
- Author(s)
  Nakao Yosuke、Nakagawa Shigeki、Yamashita Yo-ichi、Umezaki Naoki、Okamoto Yuya、Ogata Yoko、Yasuda-Yoshihara Noriko、Itoyama Rumi、Yusa Toshihiko、Yamashita Kohei、Miyata Tatsunori、Okabe Hirohisa、Hayashi Hiromitsu、Imai Katsunori、Baba Hideo
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: － Issue: 8 Pages: 4733-4743
- DOI
  10.1245/s10434-020-09383-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16418, KAKENHI-PROJECT-19K18124, KAKENHI-PROJECT-21K08757
[Journal Article] Steatohepatitic Variant of Hepatocellular Carcinoma Is Associated With Both Alcoholic Steatohepatitis and Nonalcoholic Steatohepatitis2020
- Author(s)
  Qin Jia、Higashi Takaaki、Nakagawa Shigeki、Fujiwara Naoto、Yamashita Yo-ichi、Beppu Toru、Baba Hideo、Kobayashi Masahiro、Kumada Hiromitsu、Gunasekaran Ganesh、Schiano Thomas D.、Thung Swan N.、Fiel Maria Isabel、Hoshida Yujin、Ward Stephen C.
- Journal Title
  
  American Journal of Surgical Pathology
  
  Volume: 44 Issue: 10 Pages: 1406-1412
- DOI
  10.1097/pas.0000000000001533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07777
[Journal Article] Lysyl oxidase induces epithelial‐mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinoma2019
- Author(s)
  Umezaki Naoki、Nakagawa Shigeki、Yamashita Yo‐ichi、Kitano Yuki、Arima Kota、Miyata Tatsunori、Hiyoshi Yukiharu、Okabe Hirohisa、Nitta Hidetoshi、Hayashi Hiromitsu、Imai Katsunori、Chikamoto Akira、Baba Hideo
- Journal Title
  
  Cancer Science
  
  Volume: 110(6) Issue: 6 Pages: 2033-2043
- DOI
  10.1111/cas.14010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19939, KAKENHI-PROJECT-19K16721, KAKENHI-PROJECT-17K10670
[Journal Article] Conophylline suppresses pancreatic cancer desmoplasia and cancer-promoting cytokines produced by cancer-associated fibroblasts2019
- Author(s)
  N. Ishii, K. Araki, T. Yokobori, K. Hagiwara, G. Dolgormaa, T. Yamanaka, T. Handa, M. Tsukagoshi, T. Igarashi, A. Watanabe, N. Kubo, N. Harimoto, A. Masamune, K. Umezawa, H. Kuwano, K. Shirabe
- Journal Title
  
  Cancer Science
  
  Volume: 10 Issue: 1 Pages: 334-434
- DOI
  10.1111/cas.13874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01967, KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-17K10704
[Journal Article] Validation of Functional Assessment for Liver Resection Considering Venous Occlusive Area after Extended Hepatectomy.2019
- Author(s)
  Nitta H, Kitano Y, Miyata T, Nakagawa S, Mima K, Okabe H, Hayashi H, Imai K, Yamashita YI, Chikamoto A, Beppu T, Baba H.
- Journal Title
  
  J Gastrointest Surg.
  
  Volume: 24 Issue: 7 Pages: 1510-1519
- DOI
  10.1007/s11605-019-04234-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07777
[Journal Article] Enhancer of zeste homolog 2 (EZH2) regulates tumor angiogenesis and predicts recurrence and prognosis of intrahepatic cholangiocarcinoma2018
- Author(s)
  Nakagawa Shigeki、Okabe Hirohisa、Ouchi Mayuko、Tokunaga Ryuma、Umezaki Naoki、Higashi Takaaki、Kaida Takatoshi、Arima Kota、Kitano Yuki、Kuroki Hideyuki、Mima Kosuke、Nitta Hidetoshi、Imai Katsunori、Hashimoto Daisuke、Yamashita Yo-ichi、Chikamoto Akira、Baba Hideo
- Journal Title
  
  HPB
  
  Volume: 20 Issue: 10 Pages: 939-948
- DOI
  10.1016/j.hpb.2018.03.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10670, KAKENHI-PROJECT-18K16369, KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-16K19939
[Journal Article] Cell type-specific pharmacological kinase inhibition for cancer chemoprevention.2018
- Author(s)
  Deshmukh M, Nakagawa S, Higashi T, Vincek A, Venkatesh A, Ruiz de Galarreta M, Koh AP, Goossens N, Hirschfield H, Bian CB, Fujiwara N, Ono A, Hoshida H, El-Abtah M, Ahmad NB, Lujambio A, Sanchez R, Fuchs BC, Poelstra K, Prakash J, Hoshida Y.
- Journal Title
  
  Nanomedicine.
  
  Volume: 14(2) Issue: 2 Pages: 317-325
- DOI
  10.1016/j.nano.2017.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19940, KAKENHI-PROJECT-16K19939
[Journal Article] Pre-treatment double- or triple-positive tumor markers are predictive of a poor outcome for patients undergoing radiofrequency ablation for hepatocellular carcinoma.2017
- Author(s)
  itta H, Nakagawa S, Kaida T, Arima K, Higashi T, Taki K, Okabe H, Hayashi H, Hashimoto D, Chikamoto A, Ishiko T, Beppu T, Baba H.
- Journal Title
  
  Surg Today
  
  Volume: 47(3) Issue: 3 Pages: 375-384
- DOI
  10.1007/s00595-016-1385-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19939, KAKENHI-PROJECT-16K10503, KAKENHI-PROJECT-15K10171
[Journal Article] Prognostic impacts of postoperative complications in patients with intrahepatic cholangiocarcinoma after curative operations.2017
- Author(s)
  Tatsunori Miyata, Yoichi Yamashita, Takanobu Yamao, Naoki Umezaki, Masayo Tsukamoto, Yuki Kitano, Kensuke Yamamura, Kota Arima, Takayoshi Kaida, Shigeki Nakagawa, Katsunori Imai, Daisuke Hashimoto, Akira Chikamoto, Takatoshi Ishiko, Hideo Baba.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: - Issue: 3 Pages: 526-532
- DOI
  10.1007/s10147-017-1099-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460867, KAKENHI-PROJECT-15K10191
[Journal Article] Selective Venous Occlusions for Reducing Blood Loss During Right Anterior Sectionectomy of the Liver for Hepatocellular Carcinoma.2017
- Author(s)
  Yamashita Y, Imai K, Tsujita E, Kaida T, Yamao T, Umezaki N, Nakagawa S, Hashimoto D, Chikamoto A, Baba H.
- Journal Title
  
  J Am Coll Surg
  
  Volume: 224(2) Issue: 2 Pages: e5-e9
- DOI
  10.1016/j.jamcollsurg.2016.10.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19939
[Journal Article] Statin attenuates cell proliferative ability via TAZ (WWTR1) in hepatocellular carcinoma.2016
- Author(s)
  Higashi T, Hayashi H, Kitano Y, Yamamura K, Kaida T, Arima K, Taki K, Nakagawa S, Okabe H, Nitta H, Imai K, Hashimoto D, Chikamoto A, Beppu T, Baba H.
- Journal Title
  
  Med Oncol.
  
  Volume: 33(11) Issue: 11 Pages: 123-123
- DOI
  10.1007/s12032-016-0845-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10191, KAKENHI-PROJECT-16K19939, KAKENHI-PROJECT-16K19940
[Journal Article] Preoperative platelet-to-lymphocyte ratio can predict recurrence beyond the Milan criteria after hepatectomy for patients with hepatocellular carcinoma.2016
- Author(s)
  Kaida T, Nitta H, Kitano Y, Yamamura K, Arima K, Higashi T, Taki K, Nakagawa S, Okabe H, Hayashi H, Imai K, Hashimoto D, Yamashita YI, Chikamoto A, Ishiko T, Beppu T, Baba H.
- Journal Title
  
  Hepatol Res
  
  Volume: Epub ahead of print Issue: 10 Pages: 991-999
- DOI
  10.1111/hepr.12835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19939, KAKENHI-PROJECT-16K10503, KAKENHI-PROJECT-15K10171
[Journal Article] Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition.2016
- Author(s)
  Nakagawa S, Higashi T, Goossens N, Bain G, Lauwers GY, Koh AP, El-Abtah M, Ahmad NB, Hoshida H, Erstad DJ, Gunasekaran G, Lee Y, Yu ML, Chuang WL, Dai CY, Baba H, Mahajan M, Nair VD, Lanuti M, Iavarone M, Colombo M, Llovet JM, Tager AM, Schwarz ME, Chung RT, Tanabe KK, Zhang B, Fuchs BC, Hoshida Y, et al.
- Journal Title
  
  Cancer Cell
  
  Volume: 30(6) Issue: 6 Pages: 879-890
- DOI
  10.1016/j.ccell.2016.11.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19939, KAKENHI-PROJECT-16K19940
[Journal Article] Nonalcoholic Steatohepatitis Is Associated With Increased Mortality in Obese Patients Undergoing Bariatric Surgery.2016
- Author(s)
  Goossens N, Hoshida Y, Song WM, Jung M, Morel P, Nakagawa S, Zhang B, Frossard JL, Spahr L, Friedman SL, Negro F, Rubbia-Brandt L, Giostra E
- Journal Title
  
  Clin Gastroenterol Hepatol.
  
  Volume: 14(11) Issue: 11 Pages: 1619-1628
- DOI
  10.1016/j.cgh.2015.10.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19939
[Journal Article] Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma.2016
- Author(s)
  Bollard J, Miguela V, Ruiz de Galarreta M, Venkatesh A, Bian CB, Roberto MP, Tovar V, Sia D, Molina-Sanchez P, Nguyen CB, Nakagawa S, Llovet JM, Hoshida Y, Lujambio A.
- Journal Title
  
  Gut
  
  Volume: Epub ahead of print Issue: 7 Pages: 1286-1296
- DOI
  10.1136/gutjnl-2016-312268
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19939
[Journal Article] Scoring system based on tumor markers and Child-Pugh classification for HCC patients who underwent liver resection.2015
- Author(s)
  Nakagawa S, Hayashi H, Nitta H, Okabe H, Sakamoto K, Higashi T, Kuroki H, Imai K, Hashimoto D, Sakamoto Y, Chikamoto A, Beppu T, Baba H.
- Journal Title
  
  Anticancer Res
  
  Volume: 35(4) Pages: 2157-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10191
[Journal Article] Significance of P-cadherin overexpression and possible mechanism of its regulation in intrahepatic cholangiocarcinoma and pancreatic cancer.2015
- Author(s)
  Sakamoto K, Imai K, Higashi T, Taki K, Nakagawa S, Okabe H, Nitta H, Hayashi H, Chikamoto A, Ishiko T, Beppu T, Baba H.
- Journal Title
  
  Cancer Sci
  
  Volume: 106(9) Issue: 9 Pages: 1153-62
- DOI
  10.1111/cas.12732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10191, KAKENHI-PROJECT-26462045
[Journal Article] Repeated hepatic resections and radio-frequency ablations may improve the survival of adult undifferentiated embryonal sarcoma of the liver: report of two cases.2015
- Author(s)
  Masuda T, Beppu T, Doi K, Miyata T, Nakagawa S, Okabe H, Hayashi H, Ishiko T, Iyama K, Baba H.
- Journal Title
  
  Surg Case Rep
  
  Volume: 1(1) Issue: 1 Pages: 55-55
- DOI
  10.1186/s40792-015-0056-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861050
[Journal Article] Enhancer of Zeste Homolog 2 (EZH2) Promotes Progression of Cholangiocarcinoma Cells by Regulating Cell Cycle and Apoptosis.2013
- Author(s)
  Nakagawa S, Okabe H, Sakamoto Y, Hayashi H, Hashimoto D, Yokoyama N, Sakamoto K, Kuroki H, Mima K, Nitta H, Imai K, Chikamoto A, Watanabe M, Beppu T, Baba H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 3 Issue: S3 Pages: 667-675
- DOI
  10.1245/s10434-013-3135-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592008, KAKENHI-PROJECT-24592033, KAKENHI-PROJECT-25462099, KAKENHI-PROJECT-15K10191
[Presentation] 肝細胞癌の特性に応じた治療戦略開発の必要性－当科における1027例の初回肝切除経験を踏まえて－2023
- Author(s)
  宮田辰徳、林洋光、松本嵩史、上村将太、金光紘介、足立優樹、塚本雅代、中川茂樹、美馬浩介、新田英利、馬場秀夫
- Organizer
  第123回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K09059
[Presentation] 腫瘍浸潤マクロファージ由来のTNF-αがPD-L1の発現を増強し、膵癌患者における予後不良の原因となる2019
- Author(s)
  塚本雅代、今井克憲、石本崇胤、菰原義弘, 中川茂樹, 梅崎直紀, 山尾宣暢, 北野雄希, 宮田辰徳, 有馬浩太, 岡部弘尚, 山下洋市, 近本　亮, 石河隆敏, 廣田昌彦, 馬場秀夫
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10704
[Presentation] 腫瘍浸潤マクロファージ由来の TNF-αが膵癌におけるPD-L1の発現を増強し、予後不良の原因になる2019
- Author(s)
  塚本雅代、今井克憲、石本崇胤、菰原義弘、山下洋市、中川茂樹、梅崎直紀、山尾宣暢、伊東山瑠美、中尾陽佑、遊佐俊彦、宮田辰徳、岡部弘尚、近本亮、石河隆敏、廣田昌彦、馬場秀夫
- Organizer
  第40回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-17K10704
[Presentation] 腫瘍浸潤マクロファージが膵癌におけるPD-L1の発現を増強する2019
- Author(s)
  塚本雅代、今井克憲、石本崇胤、梅崎直紀、山尾宣暢、伊東山瑠美、中尾陽佑、遊佐俊彦、有馬浩太、宮田辰徳、岡部弘尚、中川茂樹、橋本大輔、山下洋市、近本亮、石河隆敏、馬場秀夫
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10704
[Presentation] 肝細胞癌における多中心性及び肝内転移再発予測の為のMolecular gene signatureの検討2018
- Author(s)
  中川茂樹、梅崎直紀、北野雄希、今井克憲、山下洋市、近本亮、馬場秀夫
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K19939
[Presentation] Molecular gene signature predictibe HCC recurrence for the precision medicine of HCC patients2018
- Author(s)
  Shigeki Nakagawa、Yo-ichi Yamashita, Naoki Umezaki, Yuki Kitano, Tatsunori Miyata, Hirohisa Okabe, Katsunori Imai, Hidetoshi Nitta, Akira Chikamoto, Hideo Baba
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-16K19939
[Presentation] 肝細胞癌初回切除例におけるBALAD scoreによるMolecular Subtype予測と臨床的意義の検討2018
- Author(s)
  中川茂樹、山下洋市、岡部弘尚、新田英利、今井克憲、林洋光、近本亮、石河隆敏、馬場秀夫
- Organizer
  JDDW 2018
- Data Source
  KAKENHI-PROJECT-16K19939
[Presentation] Lymphocitye 25-gene signature can predict the prognosis of the patients who underwent surgery for pancreatic cancer2018
- Author(s)
  Shigeki Nakagawa、Yo-ichi Yamashita, Hirohisa Okabe, Katsunori Imai, Hidetoshi Nitta, Akira Chikamoto, Hideo Baba
- Organizer
  第30回日本肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19939
[Presentation] 腹部手術歴を有する例に対する鏡視下肝切除の問題点と胸腔を活用したアプローチの工夫2018
- Author(s)
  林　洋光、高森啓史、山下洋市、生田義明、増田稔郎、岡部弘尚、中川茂樹、今井克憲、近本亮、馬場秀夫
- Organizer
  第31回日本内視鏡外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08709
[Presentation] A stromal liver gene signature predictive of HCC risk across all liver disease etiologies2018
- Author(s)
  Shigeki Nakagawa, Naoki Umesaki, Takanobu Yamao Yuki Kitano, Kensuke Yamamura, Kota Arima, Tatsunori Miyata, Takayoshi Kaida, Yujin Hoshida, Katsunori Imai,Daisuke Hashimoto, Yoichi Yamashita, Akira Chikamoto, Hideo Baba
- Organizer
  AACR 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19939
[Presentation] A stromal liver gene signature predictive of HCC risk across all liver disease etiologies2018
- Author(s)
  Shigeki Nakagawa, Naoki Umesaki, Takanobu Yamao Yuki Kitano, Kensuke Yamamura, Kota Arima, Tatsunori Miyata, Takayoshi Kaida, Yujin Hoshida, Katsunori Imai,Daisuke Hashimoto, Yoichi Yamashita, Akira Chikamoto, Hideo Baba
- Organizer
  AACR 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10191
[Presentation] 末梢血リンパ球数と膵癌根治切除術後再発の相関の検討2018
- Author(s)
  中川茂樹、山下洋市、岡部弘尚、林洋光、今井克憲、近本亮、馬場秀夫
- Organizer
  第56回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19939
[Presentation] 肝細胞癌のモレキュラーサブクラスと再発、腫瘍マーカーの検討2018
- Author(s)
  中川茂樹、山下洋市、岡部弘尚、林洋光、今井克憲、近本亮、馬場秀夫
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19939
[Presentation] 腫瘍浸潤マクロファージが膵癌におけるPD-L1の発現を増強する2017
- Author(s)
  塚本雅代、今井克憲、石本崇胤、梅崎直紀、山尾宣暢、伊東山瑠美、中尾陽佑、遊佐俊彦、北野雄希、有馬浩太、宮田辰徳、山村謙介、岡部弘尚、中川茂樹、橋本大輔、山下洋市、近本　亮、石河隆敏、馬場秀夫
- Organizer
  第28回日本消化器癌発生学会総会・第28回国際消化器癌発生会議
- Data Source
  KAKENHI-PROJECT-17K10704
[Presentation] 腫瘍浸潤マクロファージは膵癌におけるPD-L1の発現を増強し免疫寛容の原因となる2017
- Author(s)
  塚本雅代、今井克憲、石本崇胤、北野雄希、宮田辰徳、有馬浩太、岡部弘尚、中川茂樹、橋本大輔、山下洋市、近本亮、石河隆敏、馬場秀夫
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10704
[Presentation] 肝細胞癌における多中心性及び肝内転移再発予測の為のMolecular gene signatureの検討2017
- Author(s)
  中川茂樹、梅崎直紀、山尾宣暢、北野雄希、山村謙介、宮田辰徳、美馬浩介、今井克憲、橋本大輔、山下洋市、近本亮、馬場秀夫
- Organizer
  第72回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-15K10191
[Presentation] 肝切除後の血漿中Thrombospondin-1変化の肝障害の予測因子としての可能性2016
- Author(s)
  黒木秀幸、林洋光、中川茂樹、東孝暁、橋本大輔、新田英利、近本　亮、石河隆敏、別府　透、馬場秀夫
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場（大阪府）
- Data Source
  KAKENHI-PROJECT-15K19898

1. HAYASHI Hiromitsu (80625773)

# of Collaborated Projects: 9 results

# of Collaborated Products: 6 results
2. Imai Katsunori (60555746)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
3. 山下洋市 (00404070)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
4. HIGASHI Takaaki (70594878)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
5. 岡部弘尚 (40573621)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
6. 山村謙介 (10816507)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. 美馬浩介 (00546559)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. MASUDA Toshiro (50551256)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. 宮田辰徳 (80594887)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. CHIKAMOTO Akira (10419640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. KUROKI Hideyuki (50594876)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. Beppu Toru (70301372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. Tsukamoto Masayo (30836268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 日比泰造 (10338072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 清住雄希 (30827324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 石本崇胤 (00594889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 高森啓史 (90363514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 馬場秀夫 (20240905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 遊佐俊彦 (20867204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 北野雄希 (40814760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 伊東山瑠美 (50868172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 新田英利 (90555749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ISHIKO Takatoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 梅沢一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakagawa Shigeki 中川 茂樹

NAKAGAWA Shigeki 中川 茂樹

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Gene signatureによる膵癌化学療法の治療効果予測及び新規治療標的の検証Principal Investigator

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Molecular gene signature and molecular targeted therapy for pancreatic cancerPrincipal Investigator

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DKK2 targeting therapy for cholangiocarcinoma found by exhausted gene analysis.Principal Investigator

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Functional analysis of the cancer development from fatty acid metabolism and oxidative phosphorylation of HCC based on NAFLD/NASHPrincipal Investigator

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Nakagawa Shigeki 中川茂樹

NAKAGAWA Shigeki 中川茂樹