Ishii Norio 石井規夫

… Alternative Names

ISHII Norio 石井規夫

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Researcher Number	10599111
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2022: 熊本大学, 大学院生命科学研究部(医), 助教 2020: 熊本大学, 生命科学研究部, 助教 2018 – 2019: 熊本大学, 病院, 特任助教 2015 – 2018: 熊本大学, 医学部附属病院, 特任助教 2013: 熊本大学, 医学部付属病院, 医員 … More 2013: 熊本大学, 医学部附属病院, 助教 2011 – 2013: 熊本大学, 医学部附属病院, 医員 2012: 熊本大学, 医学部附属病院, その他 Less
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Metabolomics
Keywords	Principal Investigator 動脈硬化 / 細胞周期 / マクロファージ / 糖代謝・脂質代謝 / 腸内細菌叢 / 胆汁酸トランスポーター / 動脈硬化症 / 脂質代謝異常 / AMPK Except Principal Investigator 糖尿病腎症 … More / 生体分子 / 糖尿病 / cPLA2 / マクロファージ / 炎症 / 糖尿病性腎症 / 脂質代謝異常 Less

The Mechanisms of Glucose and Lipid Metabolism Regulation via Bile Acid TransportersPrincipal Investigator
- Principal Investigator
  
  Ishii Norio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kumamoto University
Downregulation of cPLA2 suppress diabetic nephropathy in diabetic mouse models
- Principal Investigator
  
  Matsumura Takeshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
The role of Skp2 in macrophage proliferation in atherosclerotic lesionPrincipal Investigator
- Principal Investigator
  
  ISHII NORIO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Investigation of mechanisms and regulatory pathways of p27kip expression in macrophages and the role of p27kip in the pathogenesis of atherosclerosisPrincipal Investigator
- Principal Investigator
  
  Ishii Norio
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
AMP-activated protein kinase in macrophage; its potential as a therapeutic target for atherosclerosisPrincipal Investigator
- Principal Investigator
  
  ISHII Norio
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Effect of overexpression of COX-2 on the progression of atherosclerosis via activation of PPARs in macrophages
- Principal Investigator
  
  YOSHINAGA Kayo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Ehime University
  Kumamoto University

All 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011

All Journal Article Presentation Book

[Book] カラー版内科学(門脇孝, 永井良三総編集):経口糖尿病薬, GLP-1, 受容体作動薬, インスリン.2012
- Author(s)
  荒木栄一, 石井規夫, 河島淳司
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-24790930
[Journal Article] Inhibition of inflammation-mediated DPP-4 expression by linagliptin increases M2 macrophages in atherosclerotic lesions2020
- Author(s)
  Nishida Shuhei、Matsumura Takeshi、Senokuchi Takafumi、Murakami-Nishida Saiko、Ishii Norio、Morita Yutaro、Yagi Yoshitaka、Motoshima Hiroyuki、Kondo Tatsuya、Araki Eiichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 524 Issue: 1 Pages: 8-15
- DOI
  10.1016/j.bbrc.2020.01.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04201, KAKENHI-PROJECT-17K09835, KAKENHI-PROJECT-17K09863, KAKENHI-PROJECT-20K08889, KAKENHI-PROJECT-18K08482
[Journal Article] Impact of tissue macrophage proliferation on peripheral and systemic insulin resistance in obese mice with diabetes.2020
- Author(s)
  Morita Y, Senokuchi T, Yamada S, Wada T, Furusho T, Matsumura T, Ishii N, Nishida S, Nishida S, Motoshima H, Komohara Y, Yamagata K, Araki E.
- Journal Title
  
  BMJ Open Diabetes Res Care
  
  Volume: 8(1) Issue: 1 Pages: e001578-e001578
- DOI
  10.1136/bmjdrc-2020-001578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08889, KAKENHI-PROJECT-19K16982, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-16H06276
[Journal Article] Comparison of the efficacy and safety of once-daily insulin degludec/insulin aspart (IDegAsp) and long-acting second-generation basal insulin (insulin degludec and insulin glargine 300 units/mL) in insulin-naïve Japanese adults with type 2 diabetes: a pilot, randomized, controlled study2019
- Author(s)
  Shimoda Seiya、Sakamoto Wakana、Hokamura Ayaka、Matsuo Yasuto、Sekigami Taiji、Ichimori Shinji、Iwashita Shinsuke、Ishii Norio、Otsu Kae、Yoshimura Ryohei、Nishiyama Toshihiko、Sakaguchi Masaji、Nishida Kenro、Araki Eiichi
- Journal Title
  
  Endocr J
  
  Volume: 66 Issue: 8 Pages: 745-752
- DOI
  10.1507/endocrj.EJ19-0179
- NAID
  130007696455
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-18K16208, KAKENHI-PROJECT-17H04201, KAKENHI-PROJECT-17K09863
[Journal Article] Pioglitazone suppresses macrophage proliferation in apolipoprotein-E deficient mice by activating PPARγ2019
- Author(s)
  Murakami-Nishida Saiko、Matsumura Takeshi、Senokuchi Takafumi、Ishii Norio、Kinoshita Hiroyuki、Yamada Sarie、Morita Yutaro、Nishida Shuhei、Motoshima Hiroyuki、Kondo Tatsuya、Komohara Yoshihiro、Araki Eiichi
- Journal Title
  
  Atherosclerosis
  
  Volume: 286 Pages: 30-39
- DOI
  10.1016/j.atherosclerosis.2019.04.229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-17H04201, KAKENHI-PROJECT-17K09835, KAKENHI-PROJECT-17K09863
[Journal Article] Inhibition of local macrophage growth ameliorates focal inflammation and suppresses atherosclerosis.2018
- Author(s)
  Yamada S, Senokuchi T, Matsumura T, Morita Y, Ishii N, Fukuda K, Murakami S, Nishida S, Kawasaki S, Motoshima H, Furukawa N, Komohara Y, Fujiwara Y, Koga T, Yamagata K, Takeya M, Araki E
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 印刷中 Issue: 5 Pages: 994-1006
- DOI
  10.1161/atvbaha.117.310320
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09835, KAKENHI-PROJECT-17K09863, KAKENHI-PROJECT-15K09394, KAKENHI-PROJECT-15K15348, KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-17H04201, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-16K09759, KAKENHI-PROJECT-16K09787, KAKENHI-PROJECT-17K16151
[Journal Article] Impacts of the 2016 Kumamoto Earthquake on glycemic control in patients with diabetes2018
- Author(s)
  Kondo Tatsuya、Miyakawa Nobukazu、Motoshima Hiroyuki、Hanatani Satoko、Ishii Norio、Igata Motoyuki、Yoshinaga Kayo、Kukidome Daisuke、Senokuchi Takafumi、Kawashima Junji、Furukawa Noboru、Matsumura Takeshi、Araki Eiichi
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 10 Issue: 2 Pages: 521-530
- DOI
  10.1111/jdi.12891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09835, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-17H04201, KAKENHI-PROJECT-17K09863
[Journal Article] Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice2016
- Author(s)
  Hanatani S, Motoshima H, Takaki Y, Kawasaki S, Igata M, Matsumura T, Kondo T, Senokuchi T, Ishii N, Kawashima J, Kukidome D, Shimoda S, Nishikawa T, Araki E
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 59 Issue: 3 Pages: 207-214
- DOI
  10.3164/jcbn.16-23
- NAID
  130005268723
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461340, KAKENHI-PROJECT-15K19519
[Journal Article] いま知っておきたい！内科最新トピックス糖尿病治療薬をどう使い分けるか.2015
- Author(s)
  石井規夫, 荒木栄一
- Journal Title
  
  内科
  
  Volume: 116(6) Pages: 919-925
- Data Source
  KAKENHI-PROJECT-15K19519
[Journal Article] 糖尿病のすべて血糖管理目標とエビデンス.2015
- Author(s)
  石井規夫, 荒木栄一
- Journal Title
  
  医学のあゆみ
  
  Volume: 252(5) Pages: 521-529
- Data Source
  KAKENHI-PROJECT-15K19519
[Journal Article] Statins meditate anti-atherosclerotic action in smooth muscle cells by peroxisome proliferator-activated receptor-γ activation.2015
- Author(s)
  Fukuda K, Matsumura T, Senokuchi T, Ishii N, Kinoshita H, Yamada S, Murakami S, Nakao S, Motoshima H, Kondo T, Kukidome D, Kawasaki S, Kawada T, Nishikawa T, Araki E
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 457 Pages: 23-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19519
[Journal Article] 特集:糖尿病治療新時代-糖尿病治療のupdate- 図説:糖尿病治療薬の作用機序2015
- Author(s)
  石井規夫, 荒木栄一
- Journal Title
  
  日本臨床
  
  Volume: 第73巻第12号,
- Data Source
  KAKENHI-PROJECT-15K19519
[Journal Article] Insulin requirement profiles in Japanese hospitalized subjects with type 2 diabetes treated with basal-bolus insulin therapy.2015
- Author(s)
  Shimoda S, Okubo M, Koga K, Sekigami T, Kawashima J, Kukidome D, Igata M, Ishii N, Shimakawa A, Matsumura T, Motoshima H, Furukawa N, Nishida K, Araki E
- Journal Title
  
  Endocr J
  
  Volume: 62 Pages: 209-216
- NAID
  130004704365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19519
[Journal Article] Regulation of TNFα converting enzyme activity in visceral adipose tissue of obese mice.2013
- Author(s)
  Kawasaki S, Motoshima H, Hanatani S, Takaki Y, Igata M, Tsutsumi A, Matsumura T, Kondo T, Senokuchi T, Ishii N, Kinoshita H, Fukuda K, Kawashima J, Shimoda S, Nishikawa T, Araki E.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 430 Pages: 1189-1194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790930
[Journal Article] Apocynin suppresses the progression of atherosclerosis in apoE-deficient mice by inactivation of macrophages2013
- Author(s)
  木下博之
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 431 Issue: 2 Pages: 124-130
- DOI
  10.1016/j.bbrc.2013.01.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590987, KAKENHI-PROJECT-23390243, KAKENHI-PROJECT-23591312, KAKENHI-PROJECT-23591337, KAKENHI-PROJECT-23791038, KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25461374
[Journal Article] Apocynin suppresses the progression of atherosclerosis in apoE-deficient mice by inactivation of macrophages2013
- Author(s)
  Kinoshita H, Matsumura T, Ishii N, Fukuda K, Senokuchi T, Motoshima H, Kondo T, Taketa K, Kawasaki S, Hanatani S, Takeya M, Nishikawa T, Araki E
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 431 Pages: 124-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591337
[Journal Article] Apocynin suppresses the progression of atherosclerosis in apoE-deficient mice by inactivation of macrophages.2013
- Author(s)
  Kinoshita H, Matsumura T, Ishii N, Fukuda K, Senokuchi T, Motoshima H, Kondo T, Taketa K, Kawasaki S, Hanatani S, Takeya M, Nishikawa T, Araki E
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 431 Pages: 124-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790930
[Journal Article] Association between circulating leukocyte subtype counts and carotid intima-media thickness in Japanese subjects with type 2 diabetes2013
- Author(s)
  Matsumura T, Taketa K, Motoshima H, Senokuchi T, Ishii N, Kinoshita H, Fukuda K, Yamada S, Kukidome D, Kondo T, Hisada A, Katoh T, Shimoda S, Nishikawa T, Araki E
- Journal Title
  
  Cardiovasc Diabetol
  
  Volume: 12 Pages: 177-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591337
[Journal Article] Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes.2013
- Author(s)
  Miyagawa K, Kondo T, Goto R, Matsuyama R, Ono K, Kitano S, Kawasaki S, Igata M, Kawashima J, Matsumura T, Motoshima H, Araki E.
- Journal Title
  
  Cardiovascular Diabetology
  
  Volume: 12(1) Issue: 1 Pages: 160-160
- DOI
  10.1186/1475-2840-12-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390243, KAKENHI-PROJECT-23591337, KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25461374
[Journal Article] DCCT, 熊本スタディ, UKPDS.2012
- Author(s)
  石井規夫, 荒木栄一:
- Journal Title
  
  動脈硬化予防 (Prevention of Arteriosclerosis)
  
  Volume: 10(4) Pages: 21-27
- Data Source
  KAKENHI-PROJECT-24790930
[Journal Article] Anti-atherosclerotic Potential of Dihydropyridine Calcium Channel Blockers2012
- Author(s)
  Ishii N, Matsumura T, Shimoda S, Araki E
- Journal Title
  
  J Atheroscler Thromb 19:693-704, 2012
  
  Volume: 19 Pages: 693-704
- NAID
  130004444628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790930
[Journal Article] Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice2011
- Author(s)
  Tsutsumi A, Motoshima H, Kondo T, Kawasaki S, Matsumura T, Hanatani S, Igata M, Ishii N, Kinoshita H, Kawashima J, Taketa K, Furukawa N, Tsuruzoe K, Nishikawa T, Araki E
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 404 Pages: 339-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591337
[Journal Article] Telmisartan exerts antiatherosclerotic effects by activating peroxisome proliferator-activated receptor-γin macrophages2011
- Author(s)
  Matsumura T, Kinoshita H, Ishii N, Fukuda K, Motoshima H, Senokuchi T, Taketa K, Kawasaki S, Nishimaki-Mogami T, Kawada T, Nishikawa T, Araki E
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31 Pages: 1268-1275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] GLP-1受容体作動薬による糖尿病大血管症進展抑制効果の機序の検討2022
- Author(s)
  八木喜崇, 松村剛, 吉永智昭, 周鈺琦, 瀬ノ口隆文, 石井規夫, 前田沙梨恵, 和田敏明, 竹下実, 荒木栄一
- Organizer
  第37回日本糖尿病合併症学会 2022/10/21,京都
- Data Source
  KAKENHI-PROJECT-20K08889
[Presentation] GLP-1 受容体作動薬による糖尿病大血管症進展抑制効果の機序の検討2022
- Author(s)
  八木喜崇, 松村剛, 吉永智昭, 周鈺琦, 瀬ノ口隆文, 石井規夫, 前田沙梨恵, 和田敏明, 竹下実, 荒木栄一
- Organizer
  第60回日本糖尿病学会九州地方会　2022/10/7,福岡
- Data Source
  KAKENHI-PROJECT-20K08889
[Presentation] デュラグルチドによる糖尿病大血管症進展抑制効果の解析2022
- Author(s)
  八木喜崇, 松村剛, 西田周平, 瀬ノ口隆文, 石井規夫, 山田沙梨恵, 西田彩子, 守田雄太郎, 和田敏明, 荒木栄一
- Organizer
  第54回日本動脈硬化学会総会・学術集会 2022/7/23，久留米
- Data Source
  KAKENHI-PROJECT-20K08889
[Presentation] Dulaglutide, one of GLP-1 receptor agonists suppresses atherosclerotic lesion formation through the regulation of MCP-1 in vascular endothelial cells.2021
- Author(s)
  4.Yagi Y, Matsumura T, Nishida S, Senokuchi T, Ishii N, Maeda S, Nishida S, Takeshita M, Yoshinaga T, Araki E.
- Organizer
  The 19th International Symposium on Atherosclerosis,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08889
[Presentation] Impacts of Local Macrophage Proliferation on Atherosclerotic Plaque Progression and Insulin Resistance in Obesity-associated Adipose Tissue.2021
- Author(s)
  6.Shi Y, Senokuchi T, Yamada S, Morita Y, Wada T, Furusho T, Kazihara N, Fukuda K, Ishii N, Matsumura T, Araki E.
- Organizer
  The 19th International Symposium on Atherosclerosis,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08889
[Presentation] DPP-4阻害薬リナグリプチンによるマクロファージM2誘導効果の機序解析.2020
- Author(s)
  西田周平, 松村　剛, 西田彩子, 瀬ノ口隆文, 石井規夫, 山田沙梨恵, 守田雄太郎, 和田敏明, 八木喜崇, 荒木栄一
- Organizer
  第51回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K08889
[Presentation] DPP-4阻害薬リナグリプチンは大動脈においてM2 MΦを増加させ動脈硬化進展抑制作用を発揮する2020
- Author(s)
  16.西田周平, 松村　剛, 西田彩子, 瀬ノ口隆文, 石井規夫, 守田雄太郎, 八木善崇, 和田敏明, 荒木栄一
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K08889
[Presentation] デュラグルチドによる糖尿病大血管症進展抑制効果2020
- Author(s)
  20.八木喜崇, 松村　剛, 西田周平, 瀬ノ口隆文, 石井規夫, 山田沙梨恵, 西田彩子, 竹下　実, 吉永智昭, 荒木栄一
- Organizer
  第58回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-20K08889
[Presentation] デュラグルチドによる糖尿病大血管症進展抑制効果の解析2020
- Author(s)
  3.八木喜崇, 松村　剛, 西田周平, 瀬ノ口隆文, 石井規夫, 山田沙梨恵, 西田彩子, 守田雄太郎, 和田敏明, 荒木栄一
- Organizer
  第51回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K08889
[Presentation] DPP-4阻害薬リナグリプチンによるマクロファージの極性変化を介した糖尿病大血管症進展抑制効果の検討2020
- Author(s)
  松村　剛，西田周平，西田彩子，瀬ノ口隆文，石井規夫，福田一起,　山田沙梨恵,　守田雄太郎，和田敏明, 八木善崇，荒木栄一
- Organizer
  第35回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-20K08889
[Presentation] Linagliptin induces M2 macrophage polarization and suppresses progression of atherosclerosis in high fat-fed apoE-deficient mice2019
- Author(s)
  Nishida S, Matsumura T, Senokuchi T, Ishii N, Murakami-Nishida S, Yamada S, Morita Y, Wada T, Motoshima H, Kondo T, Araki E
- Organizer
  The 79th ADA Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09835
[Presentation] Pioglitazone suppresses macrophage proliferation in apolipoprotein-E deficient mice by activating PPARγ.2019
- Author(s)
  Matsumura T, Nishida S.M, Nishida S, Senokuchi T, Ishii N, Morita Y, Wada T, Motoshima H, Kondo T, Arak E
- Organizer
  55th Annual Meetng of the European Association of the Study of Diabetes. 2019/9/19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] ピオグリタゾンによるマクロファージ増殖抑制効果を介した糖尿病大血管合併症進展抑制効果.2019
- Author(s)
  松村剛，西田彩子，瀬ノ口隆文，石井規夫，山田沙梨恵，守田雄太郎，西田周平，和田敏明, 佐藤美希，本島寛之，近藤龍也，荒木栄一
- Organizer
  第62回日本糖尿病学会年次学術集会 2019/5/23
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] Effects of linagliptin on macrophages and on progression of atherosclerosis in high fat-fed apoE-deficient mice.2019
- Author(s)
  Nishida S, Matsumura T, Senokuchi T, Ishii N, Murakami-Nishida S, Yamada S, Morita Y, Wada T, Motoshima H, Kondo T, Araki E
- Organizer
  The 11th Scientific Meeting of the Asian Association for the Study of Diabetes. 2019/5/23,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] ピオグリタゾンによるマクロファージ増殖抑制効果を介した糖尿病大血管合併症進展抑制効果2019
- Author(s)
  松村剛，西田彩子，瀬ノ口隆文，石井規夫，山田沙梨恵，守田雄太郎，西田周平，和田敏明, 佐藤美希，本島寛之，近藤龍也，荒木栄一
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09835
[Presentation] Effects of linagliptin on macrophages and on progression of atherosclerosis in high fat-fed apoE-deficient mice2019
- Author(s)
  Nishida S, Matsumura T, Senokuchi T, Ishii N, Murakami-Nishida S, Yamada S, Morita Y, Wada T, Motoshima H, Kondo T, Araki E
- Organizer
  The 11th Scientific Meeting of the Asian Association for the Study of Diabetes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09835
[Presentation] Pioglitazone suppresses macrophage proliferation in apolipoprotein-E deficient mice by activating PPARγ2019
- Author(s)
  Matsumura T, Murakami-Nishida S, Nishida S, Senokuchi T, Ishii N, Morita Y, Wada T, Motoshima H, Kondo T, Arak E
- Organizer
  55th Annual Meetng of the European Association of the Study of Diabetes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09835
[Presentation] Inhibition of DPP-4 suppresses atherosclerotic lesion formation through the regulation of M2 macrophage polarization2019
- Author(s)
  Yagi Y, Matsumura T, Nishida S, Senokuchi T, Ishii N, Murakami-Nishida S, Morita Y, Wada T, Motoshima H, Kondo T, Araki E
- Organizer
  IDF Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09835
[Presentation] Linagliptin induces M2 macrophage polarization and suppresses progression of atherosclerosis in high fat-fed apoE-deficient mice.2019
- Author(s)
  Nishida S, Matsumura T, Senokuchi T, Ishii N, Murakami-Nishida S, Yamada S, Morita Y, Wada T, Motoshima H, Kondo T, Araki E
- Organizer
  The 79th ADA Scientific Meeting. 2019/6/10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] マクロファージ局在のSGLT2を標的とした新規糖尿病大血管症抑制機序の解明.2018
- Author(s)
  西田彩子, 松村　剛, 瀬ノ口隆文, 石井規夫, 山田沙梨恵, 守田雄太郎, 西田周平, 佐藤美希, 本島寛之, 近藤龍也, 荒木栄一
- Organizer
  第61回日本糖尿病学会総会東京, 口演
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] Empagliflozin suppresses atherosclerotic lesion formation in apolipoprotein E deficient mice by inhibiting macrophage activation.2018
- Author(s)
  Matsumura T, Murakami-Nishida S, Senokuchi T, Ishii N, Nishida S, Kondo T, Motoshima H, Araki E.
- Organizer
  54th EASD Annual Meeting, Berlin, Germany, Oral.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] Empagliflozin, a sodium-glucose cotransporter 2 inhibitor, suppresses the progression of atherosclerosis in diabetic apoE-deficient mice.2017
- Author(s)
  1.Matsumura T, Murakami S, Senokuchi T, Ishii N, Fukuda K, Nishida S, Araki E
- Organizer
  第81回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09835
[Presentation] エンパグリフロジンによる新たな抗動脈硬化作用機序解明－マクロファージに対する直接作用－2017
- Author(s)
  村上彩子, 松村　剛, 瀬ノ口隆文, 石井規夫, 福田一起, 山田沙梨恵, 西田周平, 本島寛之, 近藤龍也, 荒木栄一
- Organizer
  第49回日本動脈硬化学会総会
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] エンパクリフロジンによる糖尿病大血管症進展抑制効果の検討.2017
- Author(s)
  村上彩子, 松村　剛, 瀬ノ口隆文, 石井規夫, 福田一起, 山田沙梨恵, 守田雄太郎, 西田周平, 佐藤美希, 本島寛之, 近藤龍也, 荒木栄一
- Organizer
  第60回日本糖尿病学会総会
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] Empagliflozin, a sodium-glucose cotransporter 2 inhibitor, suppresses the progression of atherosclerosis in diabetic apoE-deficient mice2017
- Author(s)
  Matsumura T, Murakami S, Senokuchi T, Ishii N, Fukuda K, Nishida S, Araki E
- Organizer
  第81回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] Empagliflozin, a sodium-glucose cotransporter 2 inhibitor, suppresses the progression of atherosclerosis in diabetic apoE-deficient mice2017
- Author(s)
  Murakami S, Matsumura T, Senokuchi T, Ishii N, Fukuda K, Yamada S, Morita Y, Nishida S, Sato M, Motoshima H, Kondo T, Araki E
- Organizer
  The 8th AASD Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] SGLT-2阻害薬によるマクロファージ活性抑制を介した糖尿病大血管症進展抑制効果の解析2017
- Author(s)
  松村剛, 村上彩子, 瀬ノ口隆文, 石井規夫, 山田沙理恵, 守田雄太郎, 西田周平, 久木留大介, 本島寛之, 近藤龍也, 沼田朋大, 荒木栄一
- Organizer
  第32回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] エンパクリフロジンによる糖尿病大血管症進展抑制効果の検討2017
- Author(s)
  村上彩子, 松村　剛, 瀬ノ口隆文, 石井規夫, 福田一起, 山田沙梨恵, 守田雄太郎, 西田周平, 佐藤美希, 本島寛之, 近藤龍也, 荒木栄一
- Organizer
  第67回日本体質医学会総会
- Data Source
  KAKENHI-PROJECT-17K09863
[Presentation] ストレプトゾトシン誘発糖尿病apoE欠損マウスにおいてエンパクリフロジンは大血管症進展を抑制する.2016
- Author(s)
  村上彩子, 松村剛, 瀬ノ口隆文, 石井規夫, 福田一起, 山田沙理恵, 守田雄太郎, 西田周平, 久木留大介, 本島寛之, 近藤龍也, 荒木栄一
- Organizer
  第31回日本糖尿病合併症学会
- Place of Presentation
  宮城
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K19519
[Presentation] ストレプトゾトシン誘発糖尿病apoE欠損マウスを用いたエンパクリフロジンによる大血管症進展抑制効果の検討.2016
- Author(s)
  村上彩子, 松村剛, 瀬ノ口隆文, 石井規夫, 木下博之, 福田一起, 山田沙理恵, 佐藤美希，本島寛之，近藤龍也, 荒木栄一
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K19519
[Presentation] Empagliflozin, a sodium-glucose cotransporter 2 inhibitor, suppresses the progression of atherosclerosis in diabetic apoE-deficient mice.2016
- Author(s)
  Murakami S, Matsumura T, Senokuchi T, Ishii N, Fukuda K, Nishida S, Araki E
- Organizer
  第24回日本血管生物医学会
- Place of Presentation
  長崎
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-15K19519
[Presentation] Empagliflozin, a sodium-glucose cotransporter 2 inhibitor, suppresses the progression of atherosclerosis in diabetic apoE-deficient mice.2016
- Author(s)
  Murakami S, Matsumura T, Senokuchi T, Ishii N, Fukuda K, Yamada S, Morita Y, Nishida S, Sato M, Motoshima H, Kondo T, Araki E
- Organizer
  The 8th AASD Scientific Meeting
- Place of Presentation
  Taipei International Convention Center, Taipei, Taiwan
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19519
[Presentation] 肥満における血清脂質値へのコレステロール合成・吸収能の影響2013
- Author(s)
  松村剛, 竹田佳代, 石井規夫, 本島寛之, 瀬ノ口隆文, 木下博之, 福田一起, 西川武志, 荒木栄一:
- Organizer
  第16回日本病態栄養学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] AMPK活性化によるマクロファージ増殖抑制を介した糖尿病大血管合併症発症抑制効果の解析2013
- Author(s)
  60. 石井規夫, 松村剛, 木下博之, 福田一起, 瀬ノ口隆文, 本島寛之, 西川武志, 荒木栄一
- Organizer
  第28回日本糖尿病合併症学会
- Place of Presentation
  北海道、旭川
- Data Source
  KAKENHI-PROJECT-24790930
[Presentation] AMPK活性化を介したマクロファージ増殖抑制と糖尿病大血管症抑制効果の解析2013
- Author(s)
  40. 石井規夫, 松村剛, 木下博之, 福田一起, 水流添覚, 瀬ノ口隆文, 本島寛之, 西川武志, 荒木栄一
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24790930
[Presentation] 肥満における血清脂質値へのコレステロール合成・吸収能の影響2013
- Author(s)
  松村剛,竹田佳代,石井規夫,本島寛之,瀬ノ口隆文,木下博之,福田一起,西川武志,荒木栄一:
- Organizer
  第16回日本病態栄養学会年次学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] マクロファージAMPK 活性化を介した糖尿病大血管合併症進展抑制効果の解析2013
- Author(s)
  石井規夫, 松村剛, 木下博之, 福田一起, 瀬ノ口隆文, 本島寛之, 西川武志, 荒木栄一
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本(ホテル日航熊本ほか)
- Data Source
  KAKENHI-PROJECT-24790930
[Presentation] 糖尿病大血管合併症発症・進展におけるマクロファージAMPK の役割2013
- Author(s)
  石井規夫, 松村剛, 本島寛之, 西川武志, 荒木栄一
- Organizer
  第2回Kyushu Diabetes Research Conference
- Place of Presentation
  福岡(ヒルトン福岡シーホーク)
- Year and Date
  2013-07-13
- Data Source
  KAKENHI-PROJECT-24790930
[Presentation] AMPK 活性化によるマクロファージ増殖抑制を介した糖尿病大血管合併症発症抑制効果の解析2013
- Author(s)
  石井規夫, 松村剛, 木下博之, 福田一起, 瀬ノ口隆文, 本島寛之, 西川武志, 荒木栄一
- Organizer
  第28回日本糖尿病合併症学会
- Place of Presentation
  北海道(旭川グランドホテル)
- Data Source
  KAKENHI-PROJECT-24790930
[Presentation] Activation of AMP-activated protein kinase suppresses the progression of atherosclerosis via inhibition of macrophage proliferation2012
- Author(s)
  Norio Ishii, Takeshi Matsumura, Hiroyuki Kinoshita, Kazuki Fukuda, Takafumi Senokuchi, Takeshi Nishikawa, Eiichi Araki
- Organizer
  第44回日本動脈硬化学会
- Place of Presentation
  福岡(ヒルトン福岡シーホーク)
- Data Source
  KAKENHI-PROJECT-24790930
[Presentation] 2型糖尿病における白血球分画と糖尿病血管合併症との相関2012
- Author(s)
  松村剛,竹田佳代,本島寛之,瀬ノ口隆文,石井規夫,木下博之,福田一起,西川武志,荒木栄一
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] 2型糖尿病における白血球分画と糖尿病血管合併症との相関2012
- Author(s)
  松村剛, 竹田佳代, 本島寛之, 瀬ノ口隆文, 石井規夫, 木下博之, 福田一起, 西川武志, 荒木栄一
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜，パンパシフィック横浜ベイホテル東急（神奈川）
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] NADPH oxidase阻害によるマクロファージ増殖抑制を介した大血管合併症進展抑制効果2012
- Author(s)
  木下博之, 松村剛, 福田一起, 瀬ノ口隆文, 石井規夫, 本島寛之, 竹田佳代, 西川武志, 荒木栄一
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜，パンパシフィック横浜ベイホテル東急（神奈川）
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] 肥満における血清脂質値へのコレステロール合成・吸収能の影響2012
- Author(s)
  松村剛, 竹田佳代, 石井規夫, 本島寛之, 瀬ノ口隆文, 木下博之, 福田一起, 西川武志, 荒木栄一
- Organizer
  第33回日本肥満学会
- Place of Presentation
  ホテルグランヴィア京都（京都）
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] Activation of AMP-activated protein kinase suppresses the progression of atherosclerosis via inhibition of macrophage proliferation2012
- Author(s)
  Norio Ishii, Takeshi Matsumura, Hiroyuki Kinoshita, Kazuki Fukuda, Takafumi Senokuchi, Takeshi Nishikawa, Eiichi Araki
- Organizer
  第４４回日本動脈硬化学会
- Place of Presentation
  福岡　ヒルトン福岡シーホーク
- Data Source
  KAKENHI-PROJECT-24790930
[Presentation] 2型糖尿病における大血管合併症進展の指標としての血中単球数の有用性2012
- Author(s)
  松村剛, 本島寛之, 瀬ノ口隆文, 竹田佳代, 石井規夫, 木下博之, 福田一起, 西川武志, 荒木栄一
- Organizer
  第109回日本内科学会総会
- Place of Presentation
  みやこめっせ（京都）
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] 妊娠一過性甲状腺中毒症から甲状腺クリーゼを発症した一例2012
- Author(s)
  隅倉緑, 島川明子, 石井規夫, 前田貴子, 竹田佳代, 井形元維, 河島淳司, 下田誠也, 荒木栄一
- Organizer
  日本内分泌学会九州地方会
- Place of Presentation
  久留米大学筑水会館（福岡）
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] NADPH oxidase阻害によるマクロファージ増殖抑制を介した大血管合併症進展抑制効果2012
- Author(s)
  木下博之,松村剛,福田一起,瀬ノ口隆文,石井規夫,本島寛之,竹田佳代,西川武志,荒木栄一
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] 肥満症例におけるインスリン頻回注射療法からGLP-1受容体作動薬への変更による短・中期的効果の検討2012
- Author(s)
  渡辺栄一郎, 下田誠也, 古川昇, 河島淳司, 瀬ノ口隆文, 竹田佳代, 岩下晋輔, 久木留大介, 井形元維, 石井規夫, 前田貴子, 阪口雅司, 荒木栄一
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜，パンパシフィック横浜ベイホテル東急（神奈川）
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] 肥満における血清脂質値へのコレステロール合成・吸収能の影響2012
- Author(s)
  松村剛,竹田佳代,石井規夫,本島寛之,瀬ノ口隆文,木下博之,福田一起,西川武志,荒木栄一
- Organizer
  第33回日本肥満学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] 2型糖尿病における大血管・細小血管合併症進展の指標としての白血球分画の有用性2012
- Author(s)
  松村剛,石井規夫,竹田佳代,本島寛之,木下博之,福田一起,瀬ノ口隆文,西川武志,荒木栄一
- Organizer
  第50回日本糖尿病学会九州地方会
- Place of Presentation
  久留米
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] Cytosolic phosphorlipase A2制御によるPPARγ活性化を介したインスリン抵抗性改善効果の検討2012
- Author(s)
  福田一起, 松村剛, 木下博之, 石井規夫, 瀬ノ口隆文, 本島寛之, 竹田佳代, 西川武志, 荒木栄一
- Organizer
  第50回日本糖尿病学会九州地方会
- Place of Presentation
  ホテルマリターレ創世（福岡）
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] Cytosolic phosphorlipase A2制御によるPPARγ活性化を介したインスリン抵抗性改善効果の検討2012
- Author(s)
  福田一起,松村剛,木下博之,石井規夫,瀬ノ口隆文,本島寛之,竹田佳代,西川武志,荒木栄一
- Organizer
  第50回日本糖尿病学会九州地方会
- Place of Presentation
  久留米
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] 2型糖尿病における大血管・細小血管合併症進展の指標としての白血球分画の有用性2012
- Author(s)
  松村剛, 石井規夫, 竹田佳代, 本島寛之, 木下博之, 福田一起, 瀬ノ口隆文, 西川武志, 荒木栄一
- Organizer
  第50回日本糖尿病学会九州地方会
- Place of Presentation
  ホテルマリターレ創世（福岡）
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] 2型糖尿病における大血管・細小血管合併症進展の指標としての白血球分画の有用性2012
- Author(s)
  松村剛,石井規夫,竹田佳代,本島寛之,木下博之,福田一起,瀬ノ口隆文,西川武志,荒木栄一
- Organizer
  第27回糖尿病合併症学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] Associations between circulating leukocyte subtype counts and carotid intima-media thickness in Japanese subjects with type 2 diabetes2012
- Author(s)
  Matsumura T, Taketa K, Motoshima H, Senokuchi T, Ishii N, Kinoshita H, Fukuda K, Nishikawa T, Araki E
- Organizer
  The 72th Annual Meeting of American Diabetes Association
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] スタチンによる血管構成細胞特異的PPARγ活性化とその機序解明2011
- Author(s)
  木下博之,松村剛,瀬ノ口隆文,石井規夫,福田一起,本島寛之,竹田佳代,西川武志,荒木栄一
- Organizer
  第54回日本糖尿病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] スタチンはSMCのPPARγ活性化を誘導し抗動脈硬化作用を発揮する2011
- Author(s)
  福田一起,松村剛,木下博之,石井規夫,瀬ノ口隆文,本島寛之,竹田佳代,西川武志,荒木栄一
- Organizer
  第49回日本糖尿病学会九州地方会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] 2型糖尿病における大血管合併症進展の指標としての血中単球数の有用性2011
- Author(s)
  松村剛,竹田佳代,本島寛之,石井規夫,嶋田さやか,木下博之,福田一起,西川武志,荒木栄一
- Organizer
  第54回日本糖尿病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591337
[Presentation] 高コレステロール血症合併2型糖尿病における脂質検査値と動脈硬化進展度との関連2011
- Author(s)
  嶋田さやか,松村剛,竹田佳代,本島寛之,石井規夫,西川武志,荒木栄一
- Organizer
  第54回日本糖尿病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591337

1. 瀬ノ口隆文 (00530320)

# of Collaborated Projects: 3 results

# of Collaborated Products: 31 results
2. MATSUMURA Takeshi (20398192)

# of Collaborated Projects: 2 results

# of Collaborated Products: 31 results
3. 近藤龍也 (70398204)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
4. YOSHINAGA Kayo (10537088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ARAKI Eiichi (10253733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
6. 竹田佳代

# of Collaborated Projects: 0 results

# of Collaborated Products: 20 results

Ishii Norio 石井 規夫

ISHII Norio 石井 規夫

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The Mechanisms of Glucose and Lipid Metabolism Regulation via Bile Acid TransportersPrincipal Investigator

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Downregulation of cPLA2 suppress diabetic nephropathy in diabetic mouse models

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The role of Skp2 in macrophage proliferation in atherosclerotic lesionPrincipal Investigator

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Investigation of mechanisms and regulatory pathways of p27kip expression in macrophages and the role of p27kip in the pathogenesis of atherosclerosisPrincipal Investigator

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AMP-activated protein kinase in macrophage; its potential as a therapeutic target for atherosclerosisPrincipal Investigator

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Effect of overexpression of COX-2 on the progression of atherosclerosis via activation of PPARs in macrophages

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[Book] カラー版内科学(門脇孝, 永井良三総編集):経口糖尿病薬, GLP-1, 受容体作動薬, インスリン.2012

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[Journal Article] Inhibition of inflammation-mediated DPP-4 expression by linagliptin increases M2 macrophages in atherosclerotic lesions2020

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[Journal Article] Impact of tissue macrophage proliferation on peripheral and systemic insulin resistance in obese mice with diabetes.2020

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[Journal Article] Pioglitazone suppresses macrophage proliferation in apolipoprotein-E deficient mice by activating PPARγ2019

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[Journal Article] Inhibition of local macrophage growth ameliorates focal inflammation and suppresses atherosclerosis.2018

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[Journal Article] Impacts of the 2016 Kumamoto Earthquake on glycemic control in patients with diabetes2018

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[Journal Article] Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice2016

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Ishii Norio 石井規夫

ISHII Norio 石井規夫

[Journal Article] いま知っておきたい！内科最新トピックス糖尿病治療薬をどう使い分けるか.2015

[Journal Article] 糖尿病のすべて血糖管理目標とエビデンス.2015