Nakashima Ran 中嶋蘭 (笹井蘭)

… Alternative Names

笹井蘭

中嶋蘭ナカシマラン

笹井蘭

NAKASHIMA Ran 中嶋蘭

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Researcher Number	10599525
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 京都大学, 医学研究科, 助教 2022 – 2023: 京都大学, 医学研究科, 助教 2018 – 2020: 京都大学, 医学研究科, 助教 2018: 京都大学, 大学院医学研究科, 助教 2015: 京都大学, 大学院医学研究科, 助教 2013 – 2015: 京都大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology Except Principal Investigator Collagenous pathology/Allergology
Keywords	Principal Investigator 抗MDA5抗体 / 皮膚筋炎 / 単球 / 間質性肺炎 / モデルマウス / 筋炎特異的自己抗体 / CX3CR1 / フラクタルカイン / HLA / 抗MDA抗体 / マクロファージ … More Except Principal Investigator … More 免疫抑制療法 / 間質性肺炎 / 無筋症性皮膚筋炎 / 皮膚筋炎 / 自己抗体 / IFIH1 / MDA5 / 間質性肺病変 / DDB1 / 血漿交換療法 / SFPQ / 難治性病態 / 治療 / モデルマウス / 膠原病難治性病態 Less

間質性肺疾患合併多発性筋炎/皮膚筋炎における自己抗原反応性T/B細胞の病原性解明Principal Investigator
- Principal Investigator
  
  中嶋蘭 (笹井蘭)
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kyoto University
Development of anti-MDA5-positive dermatomyositis mouse model with interstitial lung diseasePrincipal Investigator
- Principal Investigator
  
  中嶋蘭 (笹井蘭)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kyoto University
CX3CL1-CX3CR1 plays an important role in the pathophysiology of anti-MDA5-positive dermatomyositisPrincipal Investigator
- Principal Investigator
  
  Nakashima Ran
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kyoto University
Autoantibodies in dermatomyositis-associated interstitial lung disease and establishment of treatment for improved life prognosis
- Principal Investigator
  
  MImori Tsuneyo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Kyoto University
Investigation of pathogenesis and pathophisiology of anti-MDA5-positive dermatomyositisPrincipal Investigator
- Principal Investigator
  
  NAKASHIMA Ran
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Kyoto University
Study for pathological significance of autoantibodies and establishment of therapy in myositis-associated intractable acute interstitial pneumonia
- Principal Investigator
  
  MIMORI Tsuneyo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Kyoto University

All 2024 2023 2022 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book Patent Other

[Book] わかりやすい内科学　第5版　第４章　自己免疫疾患・アレルギー疾患・免疫不全２．全身性自己免疫疾患 [Ⅴ]多発性筋炎・皮膚筋炎2023
- Author(s)
  笹井(中嶋)　蘭
- Total Pages
  966
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-22K08521
[Book] 内科：【検査値を読む2020】抗MDA5抗体2020
- Author(s)
  中嶋　蘭
- Total Pages
  864
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-18K16145
[Book] リウマチ科：IIMの診断・治療における自己抗体の意義2020
- Author(s)
  中嶋　蘭
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-18K16145
[Book] リウマチ科：特発性炎症性筋疾患の予後予測因子2020
- Author(s)
  笹井　恒雄, 谷口　雅司, 中嶋　蘭
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-18K16145
[Journal Article] Anti-aminoacyl tRNA synthetase antibodies showing the discrepancy between enzyme-linked immunosorbent assay and RNA-immunoprecipitation2024
- Author(s)
  Sasai T, Ishikawa Y, Nakashima R, Isayama T, Tanizawa K, Handa T, Shirakashi M, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Yoshifuji H, Mimori T, Morinobu A.
- Journal Title
  
  Immunol Med.
  
  Volume: 15 Issue: 3 Pages: 1-10
- DOI
  10.1080/25785826.2024.2328918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08521
[Journal Article] Long-Term Prognosis of Antimelanoma Differentiation-Associated Gene 5-Positive Dermatomyositis With Interstitial Lung Disease.2023
- Author(s)
  Sasai T, Nakashima R, Tsuji H, Nakajima T, Imura Y, Yoshida Y, Hirata S, Shirakashi M, Hiwa R, Kitagori K, Akizuki S, Yoshifuji H, Mimori T, Morinobu A.
- Journal Title
  
  J Rheumatol.
  
  Volume: 50(11) Issue: 11 Pages: 1454-1461
- DOI
  10.3899/jrheum.2023-0371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08521
[Journal Article] Other iatrogenic immunodeficiency- associated lymphoproliferative disorders in a patient with anti-melanoma differentiation-associated gene 5-positive dermatomyositis: A case report and systematic literature review.2023
- Author(s)
  Nishimura N, Niwamoto T, Arai Y, Nakashima R, Terada K, Yoshizawa A, Sakamoto R, Tanizawa K, Handa T, Morinobu A, Hirai T.
- Journal Title
  
  International Journal of Rheumatic Diseases
  
  Volume: - Issue: 6 Pages: 1172-1177
- DOI
  10.1111/1756-185x.14608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08521
[Journal Article] A new autoantibody to valyl transfer RNA synthetase associated with anti-synthetase syndrome.2022
- Author(s)
  Sasai T, Nakashima R, Shirakashi M, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Yoshifuji H, Mimori T, Morinobu A.
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: - Issue: 5 Pages: e155-e157
- DOI
  10.1093/rheumatology/keac569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08521
[Journal Article] Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.2022
- Author(s)
  [Noriko Arase,Hideaki Tsuji,Hyota Takamatsu,Hui Jin,Hachiro Konaka,Yasuhito Hamaguchi,Kyoko Tonomura,Yorihisa Kotobuki,Ikuko Ueda-Hayakawa,Sumiko Matsuoka,Toru Hirano,Hideki Yorifuji,Hiroyuki Murota,Koichiro Ohmura,Ran Nakashima,Tomoharu Sato,Atsushi Kumanogoh,Ichiro Katayama,Hisashi Arase,Manabu Fujimoto]
- Journal Title
  
  Journal of autoimmunity
  
  Volume: 126 Pages: 102774-102774
- DOI
  10.1016/j.jaut.2021.102774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08296, KAKENHI-PROJECT-21K08344, KAKENHI-PROJECT-21K06971, KAKENHI-PROJECT-22K08409, KAKENHI-PROJECT-22K08521, KAKENHI-PROJECT-18H05279, KAKENHI-PROJECT-23K21438
[Journal Article] ECG Changes Through Immunosuppressive Therapy Indicate Cardiac Abnormality in Anti-MDA5 Antibody-Positive Clinically Amyopathic Dermatomyositis.2022
- Author(s)
  Matsuo T, Sasai T, Nakashima R, Kuwabara Y, Kato ET, Murakami I, Onizawa H, Akizuki S, Murakami K, Hashimoto M, Yoshifuji H, Tanaka M, Morinobu A, Mimori T.
- Journal Title
  
  Frontiers Immunology
  
  Volume: Jan 7 Pages: 765140-765140
- DOI
  10.3389/fimmu.2021.765140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08521
[Journal Article] Multicenter Prospective Study of the Efficacy and Safety of Combined Immunosuppressive Therapy With High-Dose Glucocorticoid, Tacrolimus, and Cyclophosphamide in Interstitial Lung Diseases Accompanied by Anti-Melanoma Differentiation-Associated Gene 5-Positive Dermatomyositis.2020
- Author(s)
  Tsuji H, Nakashima R, Hosono Y, Imura Y, Yagita M, Yoshifuji H, Hirata S, Nojima T, Sugiyama E, Hatta K, Taguchi Y, Katayama M, Tanizawa K, Handa T, Uozumi R, Akizuki S, Murakami K, Hashimoto M, Tanaka M, Ohmura K, Mimori T.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 72 Issue: 3 Pages: 488-498
- DOI
  10.1002/art.41105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16145
[Journal Article] Efficacy of plasma exchange in anti-MDA5-positive dermatomyositis with interstitial lung disease under combined immunosuppressive treatment2020
- Author(s)
  Shirakashi M, Nakashima R (Corresponding author), Tsuji H, Tanizawa K, Handa T, Hosono Y, Akizuki S, Murakami K, Hashimoto M, Yoshifuji H, Ohmura K, Mimori T.
- Journal Title
  
  Rheumatology (Oxford) .
  
  Volume: 59 Issue: 11 Pages: 3284-3292
- DOI
  10.1093/rheumatology/keaa123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16145
[Journal Article] Serum matrix metalloproteinase levels in polymyositis/dermatomyositis patients with interstitial lung disease2019
- Author(s)
  Nakatsuka Yoshinari, Handa Tomohiro, Nakashima Ran, et al.
- Journal Title
  
  Rheumatology
  
  Volume: NA Issue: 8 Pages: 1465-1473
- DOI
  10.1093/rheumatology/kez065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09612, KAKENHI-PROJECT-18K16145, KAKENHI-PROJECT-16H05341
[Journal Article] Efficacy of Glucocorticoids and Calcineurin Inhibitors for Anti-aminoacyl-tRNA Synthetase Antibody?positive Polymyositis/dermatomyositis?associated Interstitial Lung Disease: A Propensity Score?matched Analysis2019
- Author(s)
  Hozumi Hironao、Fujisawa Tomoyuki、Nakashima Ran、Yasui Hideki、Suzuki Yuzo、Kono Masato、Karayama Masato、Furuhashi Kazuki、Enomoto Noriyuki、Inui Naoki、Nakamura Yutaro、Mimori Tsuneyo、Suda Takafumi
- Journal Title
  
  The Journal of Rheumatology
  
  Volume: 印刷中 Issue: 5 Pages: 509-517
- DOI
  10.3899/jrheum.180778
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15947, KAKENHI-PROJECT-16H05341, KAKENHI-PROJECT-16K19448, KAKENHI-PROJECT-19K17632
[Journal Article] Clinical significance of myositis-specific autoantibodies.2018
- Author(s)
  Nakashima R
- Journal Title
  
  Immunol Med.
  
  Volume: 41 Issue: 3 Pages: 103-112
- DOI
  10.1080/25785826.2018.1531188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16145
[Journal Article] Serum neopterin as well as ferritin, soluble interleukin-2 receptor, KL-6 and anti-MDA5 antibody titer provide markers of the response to therapy in patients with interstitial lung disease complicating anti-MDA5 antibody-positive dermatomyositis.2018
- Author(s)
  Nishioka A, Tsunoda S, Abe T, Yoshikawa T, Takata M, Kitano M, Matsui K, Nakashima R, Hosono Y, Ohmura K, Mimori T, Sano H.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: - Issue: 5 Pages: 814-820
- DOI
  10.1080/14397595.2018.1548918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16145
[Journal Article] Clinical significance of soluble CD163 in polymyositis-related or dermatomyositis-related interstitial lung disease2017
- Author(s)
  Enomoto Y, Suzuki Y, Hozumi H, Mori K, Kono M, Karayama M, Furuhashi K, Fujisawa T, Enomoto N, Nakamura Y, Inui N, Suzuki D, Ogawa N, Nakashima R, Mimori T, Iwashita T, Suda T
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 19 Issue: 1 Pages: 9-9
- DOI
  10.1186/s13075-016-1214-8
- NAID
  120005973333
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09215, KAKENHI-PROJECT-16K09577, KAKENHI-PROJECT-16K19448, KAKENHI-PROJECT-16K19449, KAKENHI-PROJECT-16K08736, KAKENHI-PROJECT-16H05341
[Journal Article] Splicing factor proline/glutamine-rich is a novel autoantigen of dermatomyositis and associated with anti-melanoma differentiation-associated gene 5 antibody.2017
- Author(s)
  Hosono Y, Nakashima R, Serada S, Murakami K, Imura Y, Yoshifuji H, Ohmura K, Naka T, Mimori T
- Journal Title
  
  J Autoimmun.
  
  Volume: 77 Pages: 116-122
- DOI
  10.1016/j.jaut.2016.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05341
[Journal Article] Predictive factors for long-term outcome in polymyositis/dermatomyositis-associated interstitial lung diseases.2017
- Author(s)
  Fujisawa T, Hozumi H, Kono M, Enomoto N, Nakamura Y, Inui N, Nakashima R, Imura Y, Mimori T, Suda T.
- Journal Title
  
  Respiratory Investigation
  
  Volume: 55 Issue: 2 Pages: 130-137
- DOI
  10.1016/j.resinv.2016.09.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19449, KAKENHI-PROJECT-16H05341
[Journal Article] Clinical Utility of YKL-40 in Polymyositis/dermatomyositis-associated Interstitial Lung Disease2017
- Author(s)
  Hozumi H, Fujisawa T, Enomoto N, Nakashima R, Enomoto Y, Suzuki Y, Kono M, Karayama M, Furuhashi K, Murakami A, Inui N, Nakamura Y, Mimori T, Suda T
- Journal Title
  
  J Rheumatol
  
  Volume: 44 Issue: 9 Pages: 1394-1401
- DOI
  10.3899/jrheum.170373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09577, KAKENHI-PROJECT-16K19448, KAKENHI-PROJECT-16H05341, KAKENHI-PROJECT-16K19449
[Journal Article] The long-term outcome of interstitial lung disease with anti-aminoacyl-tRNA synthetase antibodies.2017
- Author(s)
  Tanizawa K, Handa T, Nakashima R, Kubo T, Hosono Y, Watanabe K, Aihara K, Ikezoe K, Sokai A, Nakatsuka Y, Taguchi Y, Hatta K, Noma S, Kobashi Y, Yoshizawa A, Oga T, Hirai T, Chin K, Nagai S, Izumi T, Mimori T, Mishima M
- Journal Title
  
  Respir Med.
  
  Volume: 127 Pages: 57-64
- DOI
  10.1016/j.rmed.2017.04.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05341
[Journal Article] Clinical significance and new detection system of autoantibodies in myositis with interstitial lung disease.2016
- Author(s)
  Nakashima R, Hosono Y, Mimori T
- Journal Title
  
  Lupus
  
  Volume: 25(8) Issue: 8 Pages: 925-933
- DOI
  10.1177/0961203316651748
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05341
[Journal Article] Clinical significance and new detection system of autoantibodies in myositis with interstitial lung disease.2016
- Author(s)
  Nakashima, Hosono Y, Mimori T
- Journal Title
  
  Lupus (in press)
  
  Volume: 00 Pages: 00-00
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293222
[Journal Article] Comprehensive assessment of myositis-specific autoantibodies in polymyositis/ dermatomyositis- associated interstitial lung disease.2016
- Author(s)
  Hozumi H, Fujisawa T, Nakashima R, Johkoh T, Sumikawa H, Murakami A, Enomoto N, Inui N, Nakamura Y, Hosono Y, Imura Y, Mimori T, Suda T
- Journal Title
  
  Respir Med.
  
  Volume: 121 Pages: 91-99
- DOI
  10.1016/j.rmed.2016.10.019
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05341, KAKENHI-PROJECT-16K19449
[Journal Article] Two cases of autoimmune and secondary pulmonary alveolar proteinosis during immunosuppressive therapy in dermatomyositis with interstitial lung disease.2016
- Author(s)
  Imura Y, Yukawa N, Handa T, Nakashima R, Murakami K, Yoshifuji H, Ohmura K, Ishii H, Nakata K, Mimori T:
- Journal Title
  
  Mod Rheumatol. [Epub ahead of print]
  
  Volume: 00 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293222
[Journal Article] Prognostic Significance of Anti-Aminoacyl-tRNA Synthetase Antibodies in Polymyositis/Dermatomyositis-Associated Interstitial Lung Disease: A Retrospective Case Control Study.2015
- Author(s)
  Hozumi H, Enomoto N, Kono M, Fujisawa T, Inui N, Nakamura Y, Sumikawa H, Johkoh T, Nakashima R, Imura Y, Mimori T, Suda T
- Journal Title
  
  PLoS One
  
  Volume: 19;10(3) Issue: 3 Pages: e0120313-e0120313
- DOI
  10.1371/journal.pone.0120313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591160, KAKENHI-PROJECT-25293222, KAKENHI-PROJECT-26461186
[Journal Article] Two patients in the same family with anti-ARS antibody-associated myositis" to Rheumatology.2014
- Author(s)
  Ozaki T, Yamashita H, Hosono Y, Nakashima R, Mimori T, Takahashi Y, Kaneko H, Kano T, Mimori A
- Journal Title
  
  Mod Rheumatol
  
  Volume: 24(4) Issue: 4 Pages: 699-700
- DOI
  10.3109/14397595.2013.844299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293222
[Journal Article] Amyopathic Dermatomyositis Complicated with Eosinophilic Pneumonia2014
- Author(s)
  Iijima Y, Furusawa H, Tateishi T, Tsuchiya K, Fujie T, Tamaoka M, Sakashita H, Miyazaki Y, Sumi Y, Hosono Y, Nakashima R, Mimori T, Inase N
- Journal Title
  
  Intern. Med.
  
  Volume: 53 Issue: 14 Pages: 1539-1544
- DOI
  10.2169/internalmedicine.53.0738
- NAID
  130004466386
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293222
[Journal Article] Autoantibodies to DNA mismatch repair enzymes in polymyositis/dermatomyositis and other autoimmune diseases: a possible marker of favorable prognosis2014
- Author(s)
  Muro Y, Nakashima R, Hosono Y, Sugiura K, Mimori T, Akiyama M
- Journal Title
  
  Arthritis Rheumatol
  
  Volume: 66 Issue: 12 Pages: 3457-3462
- DOI
  10.1002/art.38866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591617, KAKENHI-PROJECT-25293222, KAKENHI-PROJECT-26461656, KAKENHI-PROJECT-26670526
[Journal Article] The multicenter study of a new assay for simultaneous detection of multiple anti-aminoacyl-tRNA synthetases in myositis and interstitial pneumonia.2014
- Author(s)
  Nakashima R, Imura Y, Hosono Y, Seto M, Murakami A, Watanabe K, Handa T, Mishima M, Hirakata M, Takeuchi T, Fujio K, Yamamoto K, Kohsaka H, Takasaki Y, Enomoto N, Suda T, Chida K, Hisata S, Nukiwa T, Mimori T
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 1 Pages: e85062-e85062
- DOI
  10.1371/journal.pone.0085062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293222
[Journal Article] Two patients in the same family with anti-ARS antibody-associated myositis.2014
- Author(s)
  Ozaki T, Yamashita H, Hosono Y, Nakashima R, Mimori T, Takahashi Y, Kaneko H, Kano T, Mimori A
- Journal Title
  
  Mod Rheumatol. [Epub ahead of print]
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293222
[Journal Article] The prognostic value of HRCT in myositis-associated interstitial lung disease.2013
- Author(s)
  Tanizawa K, Handa T, Nakashima R, Kubo T, Hosono Y, Aihara K, Ikezoe K, Watanabe K, Taguchi Y, Hatta K, Oga T, Chin K, Nagai S, Mimori T, Mishima M
- Journal Title
  
  Respiratory Medicine
  
  Volume: 107 Pages: 745-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860808
[Journal Article] The prognostic value of HRCT in myositis-associated interstitial lung disease.2013
- Author(s)
  Tanizawa K, Handa T, Nakashima R, Kubo T, Hosono Y, Aihara K, Ikezoe K, Watanabe K, Taguchi Y, Hatta K, Oga T, Chin K, Nagai S, Mimori T, Mishima M
- Journal Title
  
  Respir Med.
  
  Volume: 107 Issue: 5 Pages: 745-752
- DOI
  10.1016/j.rmed.2013.01.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293222, KAKENHI-PROJECT-25461818
[Journal Article] 抗MDA5 (melanoma differentiation-associated gene 5)抗体と皮膚筋炎・急速進行性間質性肺炎2013
- Author(s)
  中嶋蘭、三森経世
- Journal Title
  
  日本臨床免疫学会会誌
  
  Volume: 36 Pages: 71-76
- NAID
  10031171396
- Data Source
  KAKENHI-PROJECT-25293222
[Journal Article] Anti-MDA5 (melanoma differentiation-associated gene 5) antibody and dermatomyositis with rapidly progressive interstitial pneumonia2013
- Author(s)
  Ran Nakashima, Tsuneyo Mimori
- Journal Title
  
  Clinical Immunology
  
  Volume: 36 Pages: 71-76
- NAID
  10031171396
- Data Source
  KAKENHI-PROJECT-25860808
[Patent] 筋疾患の診断のためのバイオマーカー2018
- Inventor(s)
  三森経世、細野祐司、中嶋蘭
- Industrial Property Rights Holder
  三森経世、細野祐司、中嶋蘭
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-16H05341
[Presentation] THE ROLE OF CX3CL1/CX3CR1 AXIS IN THE PATHOGENESIS OF ANTI-MELANOMA DIFFERENTIATION-ASSOCIATED GENE 5 ANTIBODY-POSITIVE DERMATOMYOSITIS2024
- Author(s)
  Yasuhiro Nohda, Ran Nakashima, Toshiaki Kogame, Tsuneo Sasai, Mirei Shirakashi, Ryosuke Hiwa, Hideaki Tsuji, Koji Kitagori, Shuji Akizuki, Hajime Yoshifuji, Kenji Kabashima, and Akio Morinobu
- Organizer
  EULAR2024(european congress of rheumatology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08521
[Presentation] 炎症性ミオパチーの病態と治療　筋炎の自己抗体2022
- Author(s)
  中嶋蘭
- Organizer
  第40回日本神経治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08521
[Presentation] 小児期・成人発症の特発性炎症性筋疾患における自己抗体と臨床症状の関連性2022
- Author(s)
  辻英輝, 中嶋蘭, 白柏魅怜, 鬼澤秀夫, 日和良介, 北郡宏次, 秋月修治, 大西輝, 吉藤元, 田中真生, 八角高裕, 市村裕輝, 沖山奈緒子, 森信暁雄
- Organizer
  第31回日本小児リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08521
[Presentation] 皮膚筋炎のマネジメントUp to Date2022
- Author(s)
  中嶋蘭
- Organizer
  第121回日本皮膚科学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08521
[Presentation] 抗MDA5抗体陽性筋炎に対するアフェレシス2020
- Author(s)
  中嶋　蘭
- Organizer
  第41回日本アフェレシス学会
- Data Source
  KAKENHI-PROJECT-18K16145
[Presentation] 筋炎治療戦略の新展開　臨床試験の結果から2020
- Author(s)
  中嶋　蘭
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K16145
[Presentation] 多発性筋炎/皮膚筋炎の特異的自己抗体と臨床像2020
- Author(s)
  中嶋　蘭
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K16145
[Presentation] 身体所見と自己抗体検査2020
- Author(s)
  中嶋　蘭
- Organizer
  第60回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K16145
[Presentation] 成人皮膚筋炎における筋炎特異的自己抗体と間質性肺炎2019
- Author(s)
  中嶋　蘭
- Organizer
  第29回日本小児リウマチ学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K16145
[Presentation] Maintenance Therapy for Anti-MDA5-Positive Dermatomyositis Patients with Interstitial Lung Disease - Can They Achieve Drug-Free Remission ?-2019
- Author(s)
  Tsuneo Sasai, Ran Nakashima, Hideaki Tsuji, Shuji Akizuki, Kosaku Murakami, Motomu Hashimoto, Hajime Yoshifuji, Masao Tanaka, Koichiro Ohmura, Tsuneyo Mimori
- Organizer
  American College of Rheumatology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16145
[Presentation] 抗MDA5交替妖精間質性肺炎合併皮膚筋炎における血漿交換の有用性と治療適応の検討（ポスター発表）．2019
- Author(s)
  白柏魅怜、中嶋蘭、三森経世、他：
- Organizer
  第116回日本内科学会講演会（名古屋）
- Data Source
  KAKENHI-PROJECT-16H05341
[Presentation] 特発性炎症性筋疾患におけるマネジメントと自己抗体2019
- Author(s)
  中嶋　蘭
- Organizer
  第47回日本臨床免疫学会
- Data Source
  KAKENHI-PROJECT-18K16145
[Presentation] 抗MDA5抗体陽性間質性肺炎合併皮膚筋炎患者に対するステロイド、タクロリムス、シクロフォスファミド併用療法の有効性と安全性に関する多施設前向き研究2019
- Author(s)
  辻　英輝, 中嶋　蘭, 細野　祐司, 井村　嘉孝, 八木田　正人, 吉藤　元, 平田　信太郎, 野島　崇樹, 杉山　英二, 八田　和大, 田口　義夫, 片山　昌紀, 秋月　修治, 村上　孝作, 橋本　求, 田中真生, 大村浩一郎, 三森経世
- Organizer
  第63回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K16145
[Presentation] Efficacy and Safety of Combined Immunosuppressive Therapy with High-Dose Glucocorticoid, Tacrolimus, and Cyclophosphamide in Interstitial Lung Disease Accompanied by Anti-MDA5-Positive Dermatomyositis -A Multicenter Prospective Study (Oral, Plenary Session).2018
- Author(s)
  Tsuji H, Nakashima R, Mimori T, et al:
- Organizer
  American College of Rheumatology 2018 (Chicago, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05341
[Presentation] Efficacy and Safety of Combined Immunosuppressive Therapy with High-Dose Glucocorticoid, Tacrolimus, and Cyclophosphamide in Interstitial Lung Disease Accompanied by Anti-MDA5-Positive Dermatomyositis -A Multicenter Prospective Study -2018
- Author(s)
  Hideaki Tsuji, Ran Nakashima, Yoshitaka Imura, Masato Yagita, Hajime Yoshifuji, Shintaro Hirata, Takaki Nojima, Eiji Sugiyama, Kazuhiro Hatta, Yoshio Taguchi, Masaki Katayama, Shuji Akizuki, Kosaku Murakami, Motomu Hashimoto, Masao Tanaka, Koichiro Ohmura, Tsuneyo Mimori
- Organizer
  American College of Rheumatology 2018 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16145
[Presentation] Splicing factor proline/glutamine-rich (SFPQ) is a novel autoantigen associated with anti-MDA5 antibody in dermatomyositis and clinically amyopathic dermatomyositis2017
- Author(s)
  Hosono Y, Nakashima R, Mimori T
- Organizer
  LUPUS2017/ Asian Congress on Autoimmunity
- Place of Presentation
  Melbourne
- Year and Date
  2017-03-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05341
[Presentation] Predictive factors of poor prognosis and utility of plasmaexchange in anti-MDA5(+)dermatomyositis with interstitial lung disease under immunosuppressive therapy.2016
- Author(s)
  Mirei Shirakashi, Ran Nakashima, Yuji Hosono, Kosaku Murakami, Motomu Hashimoto, Naoichiro Yukawa, Yoshitaka Imura, Hajime Yoshifuji, Masao Tanaka, Koichiro Ohmura, Tsuneyo Mimori
- Organizer
  The 13th International Workshop on Autoantibodies and Autoimmunity
- Place of Presentation
  Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05341
[Presentation] Splicing Factor Proline/Glutamine-Rich Is a Novel Autoantigen of Dermatomyositis and Associated with Anti-Melanoma Differentiation-Associated Gene 5 Antibody.2016
- Author(s)
  Yuji Hosono, Ran Nakashima, Kosaku Murakami, Yoshitaka Imura, Satoshi Serada, Minoru Fujimoto, Hajime Yoshifuji, Koichiro Ohmura, Tetsuji Naka and Tsuneyo Mimori.
- Organizer
  American College of Rheumatology2016/9/28
- Place of Presentation
  Washington, DC
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05341
[Presentation] Risk factors for life prognosis of interstitial lung disease in dermatomyositis patients with anti-MDA 5 antibody2015
- Author(s)
  Yuji Hosono, Ran Nakashima, Yoshitaka Imura, Naoichiro Yukawa, Hajime Yoshifuji, Koichiro Ohmura and Tsuneyo Mimori
- Organizer
  American college of Rheumatology Annual Meeting 2015
- Place of Presentation
  San Francisco
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860808
[Presentation] Risk factors for life prognosis of interstitial lung disease in dermatomyositis patients with anti-melanoma differentiation-associated gene 5 antibody.2015
- Author(s)
  Hosono Y, Nakashima R, Mimori T
- Organizer
  12th Dresden Symposium on Autoantibodies
- Place of Presentation
  Dresden, Germany
- Year and Date
  2015-09-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293222
[Presentation] The Clinical Features of Recurrent Interstitial Lung Disease in Dermatomyositis Patients with Anti- Melanoma Differentiation-Associated Gene 5 Antibody.2015
- Author(s)
  Hosono Y, Nakashima R, Mimori T et al,
- Organizer
  American College of Rheumatology 2015
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293222
[Presentation] 筋炎における難治性間質性肺炎の治療2014
- Author(s)
  細野祐司、中嶋蘭、三森経世
- Organizer
  第58回日本リウマチ学会（シンポジウム）
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293222
[Presentation] The onset of myositis with myositis-specific autoantibodies (MSAs) are associated with the seasons.2013
- Author(s)
  Yuji Hosono, Ran Nakashima, Yoshitaka Imura, Naoichiro Yukawa, Hajime Yoshifuji, Motomu Hashimoto, Koichiro Ohmura, Takao Fujii and Tsuneyo Mimori
- Organizer
  EULAR
- Place of Presentation
  Madrid
- Data Source
  KAKENHI-PROJECT-25860808
[Presentation] 急速進行性間質性肺炎を合併する抗MDA5抗体陽性皮膚筋炎の強力免疫抑制療法による生命予後の改善2013
- Author(s)
  中嶋　蘭、細野　祐司、井村　嘉孝、湯川　尚一郎、吉藤　元、大村　浩一郎、藤井　隆夫、三森　経世
- Organizer
  第110回日本内科学会講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860808
[Presentation] The onset of myositis with myositis-specific autoantibodies (MSAs) are associated with the seasons.2013
- Author(s)
  Hosono Y, Nakashima R, Imura Y, Yukawa N, Yoshifuji H, Hashimoto M, Ohmura K, Fujii T, Mimori T
- Organizer
  EULAR2013 (European League Against Rheumatism)
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-25293222
[Presentation] 多発性筋炎/皮膚筋炎に伴う間質性肺炎の新しい診断と治療アプローチ2013
- Author(s)
  中嶋　蘭
- Organizer
  第23回日本リウマチ学会近畿支部集会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25860808
[Presentation] Change of anti-MDA5 antibody titer is the useful marker for predicting of resistance to therapy in dermatomyositis with interstitial pneumonia.
- Author(s)
  Hosono Y, Nakashima R, Mimori T, et al
- Organizer
  12th International Workshop on Autoimmunity and Autoantibodies
- Place of Presentation
  San Paulo, Brazil
- Year and Date
  2014-08-28 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-25293222
[Presentation] The early use of cyclosporine is beneficial for long-term prognosis in patients of polymyositis/ dermatomyositis-associated interstitial lung disease with anti-synthetase antibodies.
- Author(s)
  Hosono Y, Nakashima R, Mimori T, et al
- Organizer
  American College of Rheumatology (ACR2014)
- Place of Presentation
  Boston, USA, Nov. 17, 2014.
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25293222
[Presentation] 筋炎における難治性間質性肺炎の治療（シンポジウム「膠原病の新規治療」）
- Author(s)
  細野祐司、中嶋蘭、三森経世
- Organizer
  第58回日本リウマチ学会
- Place of Presentation
  東京
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-25293222
[]

1. MIMORI Tsuneyo (10157589)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
2. OMURA Koichiro (40432372)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. YOSHIFUJI Hajime (20422975)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. IMURA Yoshitaka (60456895)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. FUJII Takao (70255462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. YUKAWA Naoichiro (90422972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. TERAO Chikashi (60610459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MURAKAMI Kousaku (70599927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 佐藤篤靖 (30706677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 橋本求 (60512845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. HOSONO Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. TSUJI Hideki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. YAGITA Nasato

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HATTA Kazuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. NOJIMA Takaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KATAYAMA Masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NAKAMURA Yutaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 須田隆文

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. 半田知宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 杉浦一充

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 室慶直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 穗積宏尚

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 荒瀬規子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 榎本紀之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 鈴木勇三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 古橋一樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakashima Ran 中嶋 蘭 (笹井 蘭)

笹井 蘭

中嶋 蘭 ナカシマ ラン

笹井蘭

NAKASHIMA Ran 中嶋 蘭

Research Projects

Research Products

Co-Researchers

間質性肺疾患合併多発性筋炎/皮膚筋炎における自己抗原反応性T/B細胞の病原性解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of anti-MDA5-positive dermatomyositis mouse model with interstitial lung diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

CX3CL1-CX3CR1 plays an important role in the pathophysiology of anti-MDA5-positive dermatomyositisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Autoantibodies in dermatomyositis-associated interstitial lung disease and establishment of treatment for improved life prognosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of pathogenesis and pathophisiology of anti-MDA5-positive dermatomyositisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study for pathological significance of autoantibodies and establishment of therapy in myositis-associated intractable acute interstitial pneumonia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] わかりやすい内科学 第5版 第４章 自己免疫疾患・アレルギー疾患・免疫不全 ２．全身性自己免疫疾患 [Ⅴ]多発性筋炎・皮膚筋炎2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 内科：【検査値を読む2020】抗MDA5抗体2020

Author(s)

Total Pages

Publisher

Data Source

[Book] リウマチ科：IIMの診断・治療における自己抗体の意義2020

Author(s)

Publisher

Data Source

[Book] リウマチ科：特発性炎症性筋疾患の予後予測因子2020

Author(s)

Publisher

Data Source

[Journal Article] Anti-aminoacyl tRNA synthetase antibodies showing the discrepancy between enzyme-linked immunosorbent assay and RNA-immunoprecipitation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-Term Prognosis of Antimelanoma Differentiation-Associated Gene 5-Positive Dermatomyositis With Interstitial Lung Disease.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Other iatrogenic immunodeficiency- associated lymphoproliferative disorders in a patient with anti-melanoma differentiation-associated gene 5-positive dermatomyositis: A case report and systematic literature review.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A new autoantibody to valyl transfer RNA synthetase associated with anti-synthetase syndrome.2022

Author(s)

Journal Title

Nakashima Ran 中嶋蘭 (笹井蘭)

笹井蘭

中嶋蘭ナカシマラン

NAKASHIMA Ran 中嶋蘭

[Book] わかりやすい内科学　第5版　第４章　自己免疫疾患・アレルギー疾患・免疫不全２．全身性自己免疫疾患 [Ⅴ]多発性筋炎・皮膚筋炎2023