Shindo Keisuke 新堂啓祐

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SHINDO Keisuke 新堂啓祐

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Researcher Number	10602344
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定病院助教
Affiliation (based on the past Project Information) *help	2016 – 2019: 京都大学, 医学研究科, 特定病院助教 2016: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Virology Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 感染症 / 発現制御 / 蛋白質 / ウイルス / タンパク間相互作用 / プロテアソーム / ユビキチン / Viral infectivity factor / ubiquitin / ubiquitination … More / cell cycle arrest / anti-HIV drug / MDM2 / PP2A / CBF-beta / Vif / HIV-1 … More Except Principal Investigator APOBEC / 免疫学 / 遺伝子 / ゲノム / 複製複合体 / イメージング / ストレス顆粒 / RIG-I / 感染症 / ウイルス / インターフェロン / 自然免疫 Less

Elcidating the regulatory mechanisms of intracellular level and function of HIV-1 VifPrincipal Investigator
- Principal Investigator
  
  Shindo Keisuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kyoto University
Competition between viruses and intracellular antiviral immunity
- Principal Investigator
  
  Fujita Takashi
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University

All 2020 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Critical role of PP2A-B56 family protein degradation in HIV-1 Vif mediated G2 cell cycle arrest2020
- Author(s)
  Nagata Kayoko、Shindo Keisuke、Matsui Yusuke、Shirakawa Kotaro、Takaori-Kondo Akifumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 527 Issue: 1 Pages: 257-263
- DOI
  10.1016/j.bbrc.2020.04.123
- NAID
  120006865708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08807, KAKENHI-PROJECT-19K07591
[Journal Article] Core binding factor beta protects HIV-1, type 1 accessory protein viral infectivity factor from MDM2-mediated degradation2016
- Author(s)
  Yusuke Matsui, Keisuke Shindo, Kayoko Nagata, Noriyoshi Yoshinaga, Kotaro Shirakawa, Masayuki Kobayashi and Akifumi Takaori-Kondo
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 48 Pages: 24892-24899
- DOI
  10.1074/jbc.m116.734673
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08807
[Journal Article] ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction.2015
- Author(s)
  Miyakawa K, Matsunaga S, Kanou K, Matsuzawa A, Morishita R, Kudoh A, Shindo K, Yokoyama M, Sato H, Kimura H, Tamura T, Yamamoto N, Ichijo H, Takaori-Kondo A, Ryo A.
- Journal Title
  
  Nature Communications
  
  Volume: 6:6945 Issue: 1 Pages: 6945-6945
- DOI
  10.1038/ncomms7945
- NAID
  120005745628
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390115, KAKENHI-PROJECT-26860306, KAKENHI-PLANNED-24115004
[Journal Article] Abacavir, an anti–HIV-1 drug, targets TDP1-deficient adult T cell leukemia.2015
- Author(s)
  Tada K, Kobayashi M, Takiuchi Y, Iwai F, Sakamoto T, Nagata K, Shinohara M, Io K, Shirakawa K, Hishizawa M, Shindo K, Kadowaki N, Hirota K, Yamamoto J, Iwai S, Sasanuma H, Takeda S, Takaori-Kondo A.
- Journal Title
  
  Science Advances
  
  Volume: 1 Issue: 3 Pages: 1-9
- DOI
  10.1126/sciadv.1400203
- NAID
  120005601014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24115004, KAKENHI-PUBLICLY-26116518, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-25281021
[Journal Article] Defining HIV-1 Vif residues that interact with CBFβ by site-directed mutagenesis.2014
- Author(s)
  Matsui Y, Shindo K, Nagata K, Io K, Tada K, Iwai F, Kobayashi M, Kadowaki N, Harris R, Takaori-Kondo A
- Journal Title
  
  Virology
  
  Volume: 449 Pages: 82-87
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24115004
[Journal Article] CKIP-1 Is an Intrinsic Negative Regulator of T-Cell Activation through an Interaction with CARMA1.2014
- Author(s)
  Sakamoto T, Kobayashi M, Tada K, Shinohara M, Io K, Nagata K, Iwai F, Takiuchi Y, Arai Y, Yamashita K, Shindo K, Kadowaki N, Koyanagi Y, Takaori-Kondo A
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: 1-11
- DOI
  10.1371/journal.pone.0085762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390110, KAKENHI-PROJECT-23591383, KAKENHI-PROJECT-23591474, KAKENHI-PLANNED-24115004, KAKENHI-PLANNED-24115008
[Journal Article] Small molecules that inhibit Vif-induced degradation of APOBEC3G.2014
- Author(s)
  2.Matsui M, Shindo K, Izumi T, Io K, Shinohara M, Komano J, Kobayashi M, Kadowaki N, Harris RS, Takaori-Kondo A
- Journal Title
  
  Virology Journal
  
  Volume: 11 Issue: 1 Pages: 122-129
- DOI
  10.1186/1743-422x-11-122
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24115004
[Presentation] Examining HIV-1 Vif determinants for inducing the cell cycle arrest2018
- Author(s)
  Kayoko Nagata, Keisuke Shindo, Akifumi Takaori-Kondo
- Organizer
  Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-16K08807
[Presentation] The roles of PP2A degradation in HIV-1 Vif-mediated cell cycle arrest2017
- Author(s)
  Kayoko Nagata, Keisuke Shindo, Akifumi Takaori-Kondo
- Organizer
  Cold Spring Harbor Meeting on Retroviruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08807
[Presentation] PP2A-B56delta degradation is crucial for HIV-1 Vif-mediated cell cycle arrest2017
- Author(s)
  Kayoko Nagata, Keisuke Shindo, Akifumi Takaori-Kondo
- Organizer
  日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16K08807
[Presentation] Ezamining three models for Vif-mediated cell cycle arrest2016
- Author(s)
  Kayoko Nagata, Keisuke Shindo, Yusuke Matsui and Akifumi Takaori-Kondo
- Organizer
  Cold Spring Harbor Meeting on Retroviruses
- Place of Presentation
  New York, USA
- Year and Date
  2016-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08807

1. Fujita Takashi (10156870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KATO Hiroki (10597173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 高折晃史 (20324626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 小柳義夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 梁明秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shindo Keisuke 新堂 啓祐

SHINDO Keisuke 新堂 啓祐

Research Projects

Research Products

Co-Researchers

Elcidating the regulatory mechanisms of intracellular level and function of HIV-1 VifPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Competition between viruses and intracellular antiviral immunity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Critical role of PP2A-B56 family protein degradation in HIV-1 Vif mediated G2 cell cycle arrest2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Core binding factor beta protects HIV-1, type 1 accessory protein viral infectivity factor from MDM2-mediated degradation2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Abacavir, an anti&#8211;HIV-1 drug, targets TDP1-deficient adult T cell leukemia.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Defining HIV-1 Vif residues that interact with CBFβ by site-directed mutagenesis.2014

Author(s)

Journal Title

Data Source

[Journal Article] CKIP-1 Is an Intrinsic Negative Regulator of T-Cell Activation through an Interaction with CARMA1.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Small molecules that inhibit Vif-induced degradation of APOBEC3G.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Examining HIV-1 Vif determinants for inducing the cell cycle arrest2018

Author(s)

Organizer

Data Source

[Presentation] The roles of PP2A degradation in HIV-1 Vif-mediated cell cycle arrest2017

Author(s)

Organizer

Data Source

[Presentation] PP2A-B56delta degradation is crucial for HIV-1 Vif-mediated cell cycle arrest2017

Author(s)

Organizer

Data Source

[Presentation] Ezamining three models for Vif-mediated cell cycle arrest2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Shindo Keisuke 新堂啓祐

SHINDO Keisuke 新堂啓祐

[Journal Article] Abacavir, an anti–HIV-1 drug, targets TDP1-deficient adult T cell leukemia.2015