Ogasawara Mitsunari 小笠原光成

Researcher Number	10605215
Other IDs
Affiliation (Current)	2025: 高知大学, 教育研究部医療学系臨床医学部門, 講師
Affiliation (based on the past Project Information) *help	2020 – 2023: 高知大学, 教育研究部医療学系臨床医学部門, 助教 2015 – 2017: 高知大学, 教育研究部医療学系臨床医学部門, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Gastroenterology
Keywords	Principal Investigator 膵癌 / DDS / siRNA / 核酸化合物 / バイオマーカー / 術前化学療法 / 予後予測因子 / 予後予測マーカー / 肝臓学 / XBP-1 … More / PNPLA3 mutation / 遺伝子多型 / PNPLA3 / NASH Less

Efficacy evaluation of nucleic acid compounds that inhibit the invasiveness and metastasis of pancreatic cancer cells using a human pancreatic cancer mouse modelPrincipal Investigator
- Principal Investigator
  
  小笠原光成
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kochi University
Clinical application of prognostic markers for pancreatic cancer to predict postoperative prognosis at the preoperative stagePrincipal Investigator
- Principal Investigator
  
  Ogasawara Mitsunari
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kochi University
Analysis for the pathogenesis of development of NASH via ER stress by PNPLA3 gene mutant micePrincipal Investigator
- Principal Investigator
  
  Ogasawara Mitsunari
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kochi University

All 2022 2019 2017 2016

All Journal Article Presentation

[Journal Article] Upregulation of PODXL and ITGB1 in pancreatic cancer tissues preoperatively obtained by EUS-FNAB correlates with unfavorable prognosis of postoperative pancreatic cancer patients.2022
- Author(s)
  Taniuchi K, Ueno M, Yokose T, Sakaguchi M, Yoshioka R, Ogasawara M, Kosaki T, Naganuma S, Furihata M
- Journal Title
  
  PLoS One.
  
  Volume: 17(3) Issue: 3 Pages: e0265172-e0265172
- DOI
  10.1371/journal.pone.0265172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07461, KAKENHI-PROJECT-20K07699, KAKENHI-PROJECT-20K07806, KAKENHI-PROJECT-20K08359
[Journal Article] Establishment of a mouse model of pancreatic cancer using human pancreatic cancer cell line S2-013-derived organoid.2022
- Author(s)
  Tanaka C, Furihata K, Naganuma S, Ogasawara M, Yoshioka R, Taniguchi H, Furihata M, Taniuchi K
- Journal Title
  
  Human cell.
  
  Volume: 35(2) Issue: 2 Pages: 735-744
- DOI
  10.1007/s13577-022-00684-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07461, KAKENHI-PROJECT-21H04830, KAKENHI-PROJECT-20K07699, KAKENHI-PROJECT-20K07806, KAKENHI-PROJECT-20K08359
[Journal Article] KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer.2019
- Author(s)
  Taniuchi K, Ogasawara M.
- Journal Title
  
  Oncotarget
  
  Volume: 11 Issue: 2 Pages: 131-147
- DOI
  10.18632/oncotarget.27413
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09463, KAKENHI-PROJECT-19K08446, KAKENHI-PROJECT-20K07699, KAKENHI-PROJECT-20K07806, KAKENHI-PROJECT-20K08359
[Presentation] Involvement of PNPLA3 function for hepatic lipids metabolism through XBP1 and modulation of endoplasmic reticulum stress in mice2017
- Author(s)
  Nagano S，Ono M，Ochi T，Munekage K，Yano Y，Mizuta H，Ogasawara M，Hirose A，Nozalki Y，Okamoto N，Iwasaki S， Oben　JA， Saibara T
- Organizer
  APDW 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09009
[Presentation] INVOLVEMENT OF AGE-RAGE SYSTEM FOR THE DEVEL-OPMENT OF HEPATIC FIBROSIS IN NASH．2016
- Author(s)
  Munegage K，Ono M，Ochi T，Ogasawara M，Hirose A，Fujimura Y ，Iwasaki S，Saibara T
- Organizer
  uegweek2016（24th United European Gastroenterology Week）
- Place of Presentation
  Vienna, Austria
- Year and Date
  2016-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09009
[Presentation] PNPLA3 IS INVOLVED IN HEPATIC LIPIDS METABOLISM THROUGH XBP1 AND MODUALATION OF ENDOPLASMIC RETICULUM SYRESS IN MICE．2016
- Author(s)
  Ono M，Ochi T，Munegage K，Ogasawara M，Hirose A，Nozaki-Fujimura Y，Okamoto N， Iwasaki S，Oben J，Saibara T
- Organizer
  EASL（51th Annual Meeting of The European Association For The Study of The Liv
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09009

1. 谷内恵介 (50626869)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 小野正文 (70304681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 西原利治 (60145125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 降幡睦夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Ogasawara Mitsunari 小笠原 光成

Research Projects

Research Products

Co-Researchers

Efficacy evaluation of nucleic acid compounds that inhibit the invasiveness and metastasis of pancreatic cancer cells using a human pancreatic cancer mouse modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clinical application of prognostic markers for pancreatic cancer to predict postoperative prognosis at the preoperative stagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis for the pathogenesis of development of NASH via ER stress by PNPLA3 gene mutant micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Upregulation of PODXL and ITGB1 in pancreatic cancer tissues preoperatively obtained by EUS-FNAB correlates with unfavorable prognosis of postoperative pancreatic cancer patients.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of a mouse model of pancreatic cancer using human pancreatic cancer cell line S2-013-derived organoid.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Involvement of PNPLA3 function for hepatic lipids metabolism through XBP1 and modulation of endoplasmic reticulum stress in mice2017

Author(s)

Organizer

Data Source

[Presentation] INVOLVEMENT OF AGE-RAGE SYSTEM FOR THE DEVEL-OPMENT OF HEPATIC FIBROSIS IN NASH．2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] PNPLA3 IS INVOLVED IN HEPATIC LIPIDS METABOLISM THROUGH XBP1 AND MODUALATION OF ENDOPLASMIC RETICULUM SYRESS IN MICE．2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Ogasawara Mitsunari 小笠原光成