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Koshimizu Hisatsugu  小清水 久嗣

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KOSHIMIZU Hisatsugu  小清水 久嗣

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Researcher Number 10610842
Other IDs
Affiliation (Current) 2019: 藤田医科大学, その他部局等, 准教授
Affiliation (based on the past Project Information) *help 2017: 藤田保健衛生大学, 総合医科学研究所, 助教
2013 – 2015: 藤田保健衛生大学, 総合医科学研究所, 助教
Review Section/Research Field
Principal Investigator
Neurochemistry/Neuropharmacology
Except Principal Investigator
Basic / Social brain science
Keywords
Principal Investigator
細胞成熟度 / 海馬 / 歯状回 / 統合失調症 / うつ病 / モデルマウス / 精神疾患 / 神経細胞成熟度変化 / BDNF / 細胞成熟度異常 / 脳由来神経栄養因子 … More
Except Principal Investigator
… More 非成熟歯状回 / バイオインフォマティクス / 網羅的行動解析 / 3D電顕コネクトーム / Shn2欠損マウス / 神経成熟度 / 脳・神経 / 脳神経疾患 / 細胞・組織 / トランスレーショナルリサーチ / 遺伝学 / バイオテクノロジー / 神経科学 Less
  • Research Projects

    (2 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (7 People)
  •  Analysis and regulation of bi-directional changes in maturation status of brain cells utilising in vitro hightrokghput assay systemPrincipal Investigator

    • Principal Investigator
      KOSHIMIZU Hisatsugu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Fujita Health University
  •  Elucidation and regulation of bi-directional changes in neuronal maturation status

    • Principal Investigator
      Miyakawa Tsuyoshi
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Basic / Social brain science
    • Research Institution
      Fujita Health University

All 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

  • [Book] 脳科学辞典「行動テストバッテリー」2013

    • Author(s)
      高雄 啓三, 小清水 久嗣, 宮川 剛
    • Total Pages
      1
    • Publisher
      脳科学辞典編集委員会
    • Data Source
      KAKENHI-PROJECT-25430077
  • [Journal Article] Transcriptomic immaturity of the hippocampus and prefrontal cortex in patients with alcoholism2017

    • Author(s)
      Murano T, Koshimizu H, Hagihara H, *Miyakawa T.
    • Journal Title

      Scientific Reports

      Volume: 7 Pages: 44531-44531

    • DOI
      10.1038/srep44531
    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25242078, KAKENHI-PLANNED-16H06462
  • [Journal Article] Comprehensive Behavioral Analysis of Cluster of Differentiation 47 Knockout Mice2014

    • Author(s)
      Koshimizu H, Takao K, Matozaki T, Ohnishi H, Miyakawa T
    • Journal Title

      PLoS One.

      Volume: 9

    • DOI
      10.1371/journal.pone.0089584
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-23500437, KAKENHI-PUBLICLY-24111508, KAKENHI-PUBLICLY-24111546, KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25242078, KAKENHI-PROJECT-25350989, KAKENHI-PROJECT-25430077, KAKENHI-PUBLICLY-26111703, KAKENHI-PROJECT-26670110
  • [Journal Article] ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response2013

    • Author(s)
      Umemori J, Takao K, Koshimizu H, Hattori S, Furuse T, Wakana S, Miyakawa T.
    • Journal Title

      BMC Research Notes

      Volume: 6(1) Pages: 203-203

    • DOI
      10.1186/1756-0500-6-203
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-24111546, KAKENHI-PUBLICLY-25116526, KAKENHI-PROJECT-25350989, KAKENHI-PROJECT-25430077
  • [Presentation] A genome-wide association study identifies a novel locus associated with depressive state in the Japanese population2017

    • Author(s)
      Hisatsugu Koshimizu, Shinya Asano, Shoko Takahashi, Kenji Saito, and Tsuyoshi Miyakawa
    • Organizer
      第47回日本神経精神薬理学会
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] A genome-wide association study identifies a novel locus associated with depressive state in the Japanese population2017

    • Author(s)
      Koshimizu H., Asano S., Takahashi S., Saito K., Miyakawa T.
    • Organizer
      The 25th World Congress of Psychiatric Genetics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016

    • Author(s)
      小清水久嗣, 萩原英雄, 宮川剛
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis2016

    • Author(s)
      Koshimizu H., Hagihara H., Miyakawa T.
    • Organizer
      15th Annual Molecular and Cellular Cognition Society Meeting
    • Place of Presentation
      San Diego, California, USA
    • Year and Date
      2016-11-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016

    • Author(s)
      Koshimizu H., Hagihara H., Miyakawa T.
    • Organizer
      46th Annual meeting of Society for Neuroscience
    • Place of Presentation
      San Diego, California, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016

    • Author(s)
      Koshimizu H., Hagihara H., Miyakawa T.
    • Organizer
      30th CINP(The International College of Neuropsychopharmacology) World Congress of Neuropsychopharmacology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-07-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] Transcriptomic “hyper-maturity” of the hippocampus in mice2015

    • Author(s)
      Koshimizu H., Hagihara H., Ohira K., Takao T., Miyakawa T.
    • Organizer
      Society for Neuroscience 45th Annual Meeting
    • Place of Presentation
      米国シカゴ
    • Year and Date
      2015-10-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25430077
  • [Presentation] Transcriptomic “hyper-maturity” of the hippocampal dentate gyrus in mice2015

    • Author(s)
      Hisatsugu Koshimizu, Hideo Hagihara, Koji Ohira, Keizo Takao, Tsuyoshi Miyakawa
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] マウス海馬歯状回における「過成熟」現象2015

    • Author(s)
      Koshimizu H., Hagihara H., Ohira K., Keizo Takao K., Miyakawa T.
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-30
    • Data Source
      KAKENHI-PROJECT-25430077
  • [Presentation] Contrasting expression patterns for immaturity and maturity marker genes in the dentate gyrus between mouse lines with ‘immature dentate gyrus’ and mice overexpressing glucocorticoid receptor2014

    • Author(s)
      Koshimizu H., Hagihara H., Takao T., Miyakawa T.
    • Organizer
      Society for Neuroscience 44th Annual Meeting
    • Place of Presentation
      Washington, DC
    • Year and Date
      2014-11-15
    • Data Source
      KAKENHI-PROJECT-25430077
  • [Presentation] Contrasting expression pattern for immaturity and maturity marker genes in the dentate gyrus between mouse lines with “immature dentate gyrus” and mice overexpressing glucocorticoid receptor2014

    • Author(s)
      Hisatsugu Koshimizu, Hideo Hagihara, Keizo Takao, Tsuyoshi Miyakawa
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] Contrasting expression patterns for immaturity and maturity marker genes in the dentate gyrus between mouse line with ‘immature dentate gyrus’ and mice overexpressing glucocorticoid receptor2014

    • Author(s)
      Hisatsugu Koshimizu, Hideo Hagihara, Keizo Takao, Tsuyoshi Miyakawa
    • Organizer
      Molecular and Cellular Cognition Society
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2014-11-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] Contrasting expression patterns for immaturity and maturity marker genes in the dentate gyrus between mouse lines with ‘immature dentate gyrus’ and mice overexpressing glucocorticoid receptor2014

    • Author(s)
      Koshimizu H., Hagihara H., Takao T., Miyakawa T.
    • Organizer
      日本神経科学学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-12
    • Data Source
      KAKENHI-PROJECT-25430077
  • [Presentation] Transcriptomic Effects of Antidepressant Treatment and Glucocorticoid Receptor-overexpression on the Maturational Status of Brain Cells in Mice2014

    • Author(s)
      T Miyakawa, H Koshimizu, K Ohira, H Hagihara, R Takeuchi, K Takao
    • Organizer
      American College of Neuropsychopharmacology 53rd Annual Meeting
    • Place of Presentation
      Phoenix, AZ
    • Year and Date
      2014-12-09
    • Data Source
      KAKENHI-PROJECT-25430077
  • [Presentation] Contrasting expression paterns for immaturity and maturity marker genes in the dentate gyrus between mouse lines with ‘immature dentate gyrus’ and mice overexpressing glucocor8coid receptor2014

    • Author(s)
      Koshimizu H., Ohira K., Hagihara H., Takao T., Miyakawa T.
    • Organizer
      包括脳ネットワーク 冬のシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-12-12
    • Data Source
      KAKENHI-PROJECT-25430077
  • [Presentation] Dysregulation of BDNF-MAPK signaling pathway in the hippocampus of mice with “immature dentate gyrus”2013

    • Author(s)
      Koshimizu H., Ohira K., Hagihara H., Takao K., Takagi T., Kataoka M., Ishii S., Takahashi M., Miyakawa T.
    • Organizer
      第36回日本神経科学大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25430077
  • [Presentation] Dysregulation of BDNF signaling pathway in the hippocampus of mice with “immature dentate gyrus”2013

    • Author(s)
      Koshimizu H., Ohira K., Hagihara H., Takao K., Takagi T., Kataoka M., Ishii S., Takahashi M., Miyakawa T.
    • Organizer
      Annual Molecular and Cellular Cognition Society Meeting
    • Place of Presentation
      米国 San Diego
    • Data Source
      KAKENHI-PROJECT-25430077
  • [Presentation] Dysregulation of BDNF-MAPK signaling pathway in the hippocampus of mice with “immature dentate gyrus.

    • Author(s)
      Hisatsugu Koshimizu, Koji Ohira, Hideo Hagihara, Keizo Takao, Tsuyoshi Takagi, Masakazu Kataoka, Shunsuke Ishii, Masami Takahashi, Tsuyoshi Miyakawa
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego , USA
    • Year and Date
      2013-11-09 – 2013-11-13
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] Dysregulation of BDNF-MAPK signaling pathway in the hippocampus of mice with “immature dentate gyrus”

    • Author(s)
      Hisatsugu Koshimizu, Koji Ohira, Hideo Hagihara, Keizo Takao, Tsuyoshi Takagi, Masakazu Kataoka, Shunsuke Ishii, Masami Takahashi, Tsuyoshi Miyakawa
    • Organizer
      12th Annual Molecular and Cellular Congnition Society Meeting
    • Place of Presentation
      San Diego , USA
    • Year and Date
      2013-11-07 – 2013-11-08
    • Data Source
      KAKENHI-PROJECT-25242078
  • [Presentation] “Immature dentate gyrus”, a candidate endophenotype for psychotic disorders, emerges after adolescence in Schnurri-2 KO mice.

    • Author(s)
      Keizo Takao, Hideo Hagihara, Koji Ohira, Hirotaka Shoji, Satoko Hattori, Hisatsugu Koshimizu, Juzoh Umemori, Tsuyoshi Takagi, Shunsuke Ishii, Tsuyoshi Miyakawa
    • Organizer
      12th Annual Molecular and Cellular Congnition Society Meeting
    • Place of Presentation
      San Diego , USA
    • Year and Date
      2013-11-07 – 2013-11-08
    • Data Source
      KAKENHI-PROJECT-25242078
  • 1.  MIYAKAWA Tsuyoshi (10301780)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 24 results
  • 2.  TAKAO Keizo (80420397)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 3.  Ohira Koji (80402832)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  Hagihara Hideo (80514504)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 5.  UMEMORI Juzoh (20462913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  大西 浩史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  的崎 尚
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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