Ueda Motoki 上田一樹

… Alternative Names

UEDA Motoki 上田一樹

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Researcher Number	10615040
Other IDs	https://orcid.org/0000-0002-1675-809X
Affiliation (Current)	2025: 東京都立大学, 都市環境科学研究科, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 国立研究開発法人理化学研究所, 開拓研究本部, 専任研究員 2018 – 2019: 国立研究開発法人理化学研究所, 開拓研究本部, 研究員 2014 – 2017: 国立研究開発法人理化学研究所, 伊藤ナノ医工学研究室, 研究員 2014: 独立行政法人理化学研究所, 伊藤ナノ医工学研究室, 研究員 2013: 京都大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 50020:Tumor diagnostics and therapeutics-related / Polymer/Textile materials Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering/Biomaterial science and engineering / Biomedical engineering/Biological material science
Keywords	Principal Investigator がん治療 / 抗ウイルス薬 / 感染症予防 / 初期感染症治療 / 超低速細胞内移行 / 経肺投与 / ポリペプチド / ドラッグデリバリーシステム / 細胞内輸送 / 細胞取込 … More / 分子集合体 / キャリア / ペプチド / 形状 / 抗がん剤 / エンドサイトーシス / 細胞内取込 / 両親媒性ポリペプチド / ソフトマター / ドラッグデリバリー / アスペクト比 / ペプチド集合体 / ブロックコポリマー / 腫瘍イメージング / 血中半減期 / SPECT診断 / セラノスティクス / サルコシン / ABC現象 / がん診断 / SPECT / 高分子ミセル / ラクトソーム … More Except Principal Investigator 進化分子工学 / 癌治療 / 抗癌剤 / がん治療 / 高分子医薬 / 抗がん剤デリバリー / 免疫チェックポイント阻害剤 / ドラッグ・デリバリー / 免疫治療 / 超分子集合体形成 / 両親媒性ポリペプチド / ナノキャリア / 低分子医薬 / ペプチド医薬 / 医工学 / 蛍光性ペプチド / 生体材料 / 非天然アミノ酸 / ドラッグデリバリー / 蛍光発生プローブ / 生体機能利用 / バイオテクノロジー / ナノバイオ / 分子認識 / 生物・生体工学 / ドッキング・シミュレーション / 葉酸レセプター / インフルエンザ / バイオマーカー / ドラッグ・デリバリーシステム / 分子認識ペプチド / ナノメディシン / ドラッグデリバリーシステム / 中分子創薬 / 電気化学プローブ / 蛍光プローブ / ペプチドアプタマー / 固定化 / 試験管内進化法 / バイオ直交化学 / 再生医療 / タンパク質工学 / バイオマテリアル / 融合タンパク質 / 結合性 / 成長因子 Less

超長期薬理効果による感染症予防・治療薬を目指した超低速細胞内移行性キャリアの開発Principal Investigator
- Principal Investigator
  
  上田一樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Institute of Physical and Chemical Research
Multimodal cancer therapy by combination of immune therapy and targeting nanostructured carrier containing anti-cancer drug
- Principal Investigator
  
  Ito Yoshihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Institute of Physical and Chemical Research
Study of cellular uptake and cancer therapy with torpedo-shaped nanocapsulePrincipal Investigator
- Principal Investigator
  
  Ueda Motoki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Institute of Physical and Chemical Research
Creation of molecular recognition peptides for therapy and diagnosis by evolutionary molecular engineering
- Principal Investigator
  
  Ito Yoshihiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Institute of Physical and Chemical Research
Effect of hydrophilic shell of Lactosome on ABC phenomenon and theranostics using LactosomePrincipal Investigator
- Principal Investigator
  
  UEDA Motoki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Polymer/Textile materials
- Research Institution
  The Institute of Physical and Chemical Research
  Kyoto University
Creation of binding growth factors by molecular evolutionary engineering and their medical applications
- Principal Investigator
  
  ITO Yoshihiro
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The Institute of Physical and Chemical Research

All 2022 2021 2019 2014 2013 Other

All Journal Article Presentation

[Journal Article] Nanotube Formation of Amphiphilic Polypeptide Having Hydrophobic Helix Composed of Repeated Leu-Aib Sequence2022
- Author(s)
  Abosheasha Mohammed A.、Itagaki Toru、Ito Yoshihiro、Ueda Motoki
- Journal Title
  
  Peptide Science 2021
  
  Volume: 58 Pages: 145-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15334
[Journal Article] Tubular Assembly Formation Induced by Leucine Alignment along the Hydrophobic Helix of Amphiphilic Polypeptides2021
- Author(s)
  Abosheasha Mohammed A.、Itagaki Toru、Ito Yoshihiro、Ueda Motoki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 21 Pages: 12075-12075
- DOI
  10.3390/ijms222112075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15334
[Journal Article] End-sealed high aspect ratio hollow nanotube encapsulating anticancer drug - Torpedo-shaped peptidic nanocapsule2019
- Author(s)
  M. Ueda, S.Y. Seo, B.G. Nair, S. Mueller, E. Takahashi, T. Arai, T. Iyoda, S. Fujii, S. Tsuneda, Y. Ito
- Journal Title
  
  ACS Nano
  
  Volume: 13 Issue: 1 Pages: 305-312
- DOI
  10.1021/acsnano.8b06189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15334
[Journal Article] Factors Influencing in vivo Disposition of Polymeric Micelles on Multiple Administrations2014
- Author(s)
  原恵理　上田一樹　牧野顕　原功　小関英一　木村俊作
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 5 Issue: 8 Pages: 873-877
- DOI
  10.1021/ml500112u
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25810125
[Presentation] Nanotube Formation Induced by 12-residue helix of repeated Leu-Aib sequence2022
- Author(s)
  Motoki Ueda
- Organizer
  ACS national meeting spring 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15334
[Presentation] Nanotube Formation of Amphiphilic Polypeptide Having Hydrophobic Helix Composed of Repeated Leu-Aib Sequence2021
- Author(s)
  Motoki Ueda
- Organizer
  第58回日本ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18K15334
[Presentation] Solvent effects on the self-assembly of an amphiphilic polypeptide having α-helical hydrophobic block2021
- Author(s)
  Motoki Ueda
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15334
[Presentation] Peptide assembly as a model system in which co-solvent influences its morphology2021
- Author(s)
  Motoki Ueda
- Organizer
  第70回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K15334
[Presentation] Morphological Effect of Rod-Shaped Nanocarrier for Intercellular Delivery2019
- Author(s)
  M. Ueda, Y. Ito
- Organizer
  アジアバイオマテリアル学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15334
[Presentation] Morphological effect for cellular uptake of torpedo-shaped peptidic nanocapsule2019
- Author(s)
  M. Ueda, Y. Ito
- Organizer
  ACS National Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15334
[Presentation] 111In標識A3B型ラクトソームの開発と固形癌のSPECTイメージング2013
- Author(s)
  上田一樹, 栗原研輔, 原功, 小関英一, 富樫かおり, 木村俊作
- Organizer
  第53回日本核医学会学術総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-25810125
[Presentation] In標識化A3B型ラクトソームによる癌のSPECTイメージングとセラノスティックスへの展開2013
- Author(s)
  上田一樹, 富樫かおり, 小関英一, 木村俊作
- Organizer
  第62回高分子討論会
- Place of Presentation
  金沢大学角間キャンパス
- Data Source
  KAKENHI-PROJECT-25810125
[Presentation] 90Yラクトソームを用いたPEIT後の化学内照射療法ドキシルとドキソルビシンの比較
- Author(s)
  栗原研輔　上田一樹　原功　原恵理　佐野紘平　牧野顕　小関英一　清水章　佐治英郎　富樫かおり　木村俊作
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-25810125
[Presentation] Smart Materials of Molecular Assemblies Prepared from Peptidic Amphiphiles Having Hydrophobic Helices and Application for Cancer Imaging
- Author(s)
  上田一樹
- Organizer
  BIT’s 1st World Annual Congress of Smart Materials
- Place of Presentation
  Busan Exhibition & Convention Center
- Year and Date
  2015-03-23 – 2015-03-25
- Invited
- Data Source
  KAKENHI-PROJECT-25810125
[Presentation] Tumor Imaging Using Host-Guest-Type Molecular Assemblies Composed of Dendrimer Template and Amphiphilic Helical Polypeptides
- Author(s)
  上田一樹　栗原研輔　原功　富樫かおり　小関英一　木村俊作
- Organizer
  第63回高分子学会年次大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2014-05-28 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25810125
[Presentation] 111In標識および90Y標識ラクトソームを用いた固形癌の診断と治療
- Author(s)
  上田一樹, 栗原研輔, 原功, 佐野紘平, 木村博之, 小関英一, 富樫かおり, 佐治英郎, 木村俊作
- Organizer
  第13回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都ガーデンパレス
- Data Source
  KAKENHI-PROJECT-25810125

1. ITO Yoshihiro (40192497)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. TADA Seiichi (30598165)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. UZAWA Takanori (60554376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MATSUKAWA Akihiro (90264283)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YOSHIDA Yasuhiro (90281162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAKURAGI Makoto (10435828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KITAJIMA Takashi (40399556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 宮武秀行 (50291935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 植木雅志 (90312264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 秋元淳 (80649682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KURIHARA Kensuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. HARA Isao

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. HARA Eri

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

Ueda Motoki 上田 一樹

UEDA Motoki 上田 一樹

Research Projects

Research Products

Co-Researchers

超長期薬理効果による感染症予防・治療薬を目指した超低速細胞内移行性キャリアの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multimodal cancer therapy by combination of immune therapy and targeting nanostructured carrier containing anti-cancer drug

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of cellular uptake and cancer therapy with torpedo-shaped nanocapsulePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Creation of molecular recognition peptides for therapy and diagnosis by evolutionary molecular engineering

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of hydrophilic shell of Lactosome on ABC phenomenon and theranostics using LactosomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Creation of binding growth factors by molecular evolutionary engineering and their medical applications

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nanotube Formation of Amphiphilic Polypeptide Having Hydrophobic Helix Composed of Repeated Leu-Aib Sequence2022

Author(s)

Journal Title

Data Source

[Journal Article] Tubular Assembly Formation Induced by Leucine Alignment along the Hydrophobic Helix of Amphiphilic Polypeptides2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] End-sealed high aspect ratio hollow nanotube encapsulating anticancer drug - Torpedo-shaped peptidic nanocapsule2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Factors Influencing in vivo Disposition of Polymeric Micelles on Multiple Administrations2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Nanotube Formation Induced by 12-residue helix of repeated Leu-Aib sequence2022

Author(s)

Organizer

Data Source

[Presentation] Nanotube Formation of Amphiphilic Polypeptide Having Hydrophobic Helix Composed of Repeated Leu-Aib Sequence2021

Author(s)

Organizer

Data Source

[Presentation] Solvent effects on the self-assembly of an amphiphilic polypeptide having α-helical hydrophobic block2021

Author(s)

Organizer

Data Source

[Presentation] Peptide assembly as a model system in which co-solvent influences its morphology2021

Author(s)

Organizer

Data Source

[Presentation] Morphological Effect of Rod-Shaped Nanocarrier for Intercellular Delivery2019

Author(s)

Organizer

Data Source

Ueda Motoki 上田一樹

UEDA Motoki 上田一樹

[Presentation] 90Yラクトソームを用いたPEIT後の化学内照射療法ドキシルとドキソルビシンの比較