Aoyama Tomonori 青山友則

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AOYAMA Tomonori 青山友則

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Researcher Number	10622673
Affiliation (Current)	2025: 順天堂大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2014 – 2018: 順天堂大学, 医学部, 准教授 2012 – 2014: 順天堂大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 肝線維化 / 肝星細胞 / イベルメクチン / 原発性硬化性胆管炎 / リポカリン2 / 腸肝相関 / Kupffer細胞 / 腸内細菌 / リポカイン２ / マクロファージ … More / 脾臓 / ROS / 酸化ストレス / 肝組織修復機転 Less

Can "Ivermectin", an antiparasitic agent, treat primary sclerosing cholangitis?Principal Investigator
- Principal Investigator
  
  青山友則
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
Is congestion only the reason for splenomegaly in liver cirrhosis? -What are the splenic immunological effects on liver fibrosis development?-Principal Investigator
- Principal Investigator
  
  AOYAMA TOMONORI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Regulation of reactive oxidative species (ROS) production in tissue-repairing process in the liverPrincipal Investigator
- Principal Investigator
  
  AOYAMA Tomonori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University

All 2017 2016 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Spleen-derived lipocalin-2 in the portal vein regulates Kupffer cells activation and attenuates the development of liver fibrosis in mice.2017
- Author(s)
  Aoyama T, Kuwahara-Arai K, Uchiyama A, Kon K, Okubo H, Yamashina S, Ikejima K, Kokubu S, Miyazaki A, Watanabe S.
- Journal Title
  
  Lab Invest.
  
  Volume: 97 Issue: 8 Pages: 890-902
- DOI
  10.1038/labinvest.2017.44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09023, KAKENHI-PROJECT-15K19350
[Journal Article] 肝星細胞におけるSOD1とNADPHオキシダーゼ（NOX)の相互関係とROS産生2014
- Author(s)
  青山友則、内山明、栁沼礼子、福原京子、今一義、山科俊平、鈴木聡子、池嶋健一、渡辺純夫
- Journal Title
  
  アルコールと医学生物学
  
  Volume: 32 Pages: 56-59
- Data Source
  KAKENHI-PROJECT-24790721
[Journal Article] Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent.2012
- Author(s)
  青山友則
- Journal Title
  
  Hepatology
  
  Volume: 56 Issue: 6 Pages: 2316-2327
- DOI
  10.1002/hep.25938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790721
[Presentation] Spleen-derived lipocalin-2 in the portal vein, the production of which is triggered by gut-derived products, regulates Kupffer cells activation and attenuates the development of liver fibrosis in mice2016
- Author(s)
  Tomonori Aoyama
- Organizer
  Digestive Disease Week
- Place of Presentation
  アメリカ、サンディエゴ
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19350
[Presentation] Spleen-derived lipocalin-2 in the portal vein, the production of which is triggered by gut-derived products, regulates Kupffer cells activation and attenuates the development of liver fibrosis in mice.2016
- Author(s)
  青山友則
- Organizer
  Digestive Disease Week 2017
- Place of Presentation
  アメリカ合衆国カリフォルニア州サンディエゴ
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19350
[Presentation] 肝線維化進展における腸-肝相関に対する脾臓の役割2016
- Author(s)
  青山友則
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  千葉県幕張市
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K19350
[Presentation] 肝線維化進展における腸-肝相関に対する脾臓の役割2016
- Author(s)
  青山友則
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  千葉県千葉市
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K19350
[Presentation] NADPHオキシダーゼ(NOX)1によるNOX4の誘導と肝星細胞活性化.2013
- Author(s)
  青山友則.内山明.福原京子.柳沼礼子.今一義.山科俊平.池嶋健一.渡辺純夫.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790721
[Presentation] SOD1変異による肝星細胞活性化とTGF-βシグナルとの関連.2013
- Author(s)
  青山友則.内山明.柳沼礼子.福原京子.今一義.山科俊平.鈴木聡子.池嶋健一.渡辺純夫.
- Organizer
  第21回日本消化器関連学会週間
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790721
[Presentation] SOD1およびNADPHオキシターゼによるROS産生と肝星細胞活性化.2013
- Author(s)
  青山友則.デービット・ブレナー.内山明.柳沼礼子.福原京子.今一義.山科俊平.鈴木聡子.池嶋健一.渡辺純夫.
- Organizer
  第21回浜名湖シンポジウム
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-24790721
[Presentation] Iron chelater, ICL670 prevents the development of carbon tetrachloride-induced liver fibrosis in mice
- Author(s)
  Tomonori Aoyama, Akira Uchiyama, Kazuyoshi Kon, Shunhei Yamashina, Kenichi Ikejima, Sumio Watanabe
- Organizer
  Digestive Disease Week
- Place of Presentation
  シカゴ
- Year and Date
  2014-05-02 – 2014-05-05
- Data Source
  KAKENHI-PROJECT-24790721

1. DAVID Brenner

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 池嶋健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 今一義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 山科俊平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Aoyama Tomonori 青山 友則

AOYAMA Tomonori 青山 友則

Research Projects

Research Products

Co-Researchers

Can "Ivermectin", an antiparasitic agent, treat primary sclerosing cholangitis?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Is congestion only the reason for splenomegaly in liver cirrhosis? -What are the splenic immunological effects on liver fibrosis development?-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of reactive oxidative species (ROS) production in tissue-repairing process in the liverPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Spleen-derived lipocalin-2 in the portal vein regulates Kupffer cells activation and attenuates the development of liver fibrosis in mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 肝星細胞におけるSOD1とNADPHオキシダーゼ（NOX)の相互関係とROS産生2014

Author(s)

Journal Title

Data Source

[Journal Article] Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] Spleen-derived lipocalin-2 in the portal vein, the production of which is triggered by gut-derived products, regulates Kupffer cells activation and attenuates the development of liver fibrosis in mice2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Spleen-derived lipocalin-2 in the portal vein, the production of which is triggered by gut-derived products, regulates Kupffer cells activation and attenuates the development of liver fibrosis in mice.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 肝線維化進展における腸-肝相関に対する脾臓の役割2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 肝線維化進展における腸-肝相関に対する脾臓の役割2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] NADPHオキシダーゼ(NOX)1によるNOX4の誘導と肝星細胞活性化.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] SOD1変異による肝星細胞活性化とTGF-βシグナルとの関連.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] SOD1およびNADPHオキシターゼによるROS産生と肝星細胞活性化.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Iron chelater, ICL670 prevents the development of carbon tetrachloride-induced liver fibrosis in mice

Author(s)

Organizer

Place of Presentation

Aoyama Tomonori 青山友則

AOYAMA Tomonori 青山友則