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Saito Shoji  齋藤 章治

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SAITO Shoji  齋藤 章治

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Researcher Number 10623762
Other IDs
Affiliation (Current) 2025: 信州大学, 学術研究院医学系(医学部附属病院), 講師
Affiliation (based on the past Project Information) *help 2019 – 2023: 信州大学, 学術研究院医学系(医学部附属病院), 講師
2018: 信州大学, 学術研究院医学系, 助教
2013: 信州大学, 医学部附属病院, 助教
2012: 信州大学, 医学部附属病院, 特任研究員
Review Section/Research Field
Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics
Keywords
Principal Investigator
リポソーム / ナノ粒子 / キメラ抗原受容体 / がんワクチン / mRNA / CAR-T細胞 / 新規がん治療法 / 小児がん / AYA世代がん / 乳がん … More / 自殺遺伝子 / mRNA医薬 / 遺伝子治療 / アポトーシス / Caspase 9 / mRNA医薬 / CAR-T / 固形腫瘍 / 遺伝子導入T細胞療法 / T細胞療法 / 腫瘍溶解ウイルス / CAR-T療法 / がん免疫療法 / CD19抗原 / 遺伝子改変T細胞療法 / 免疫細胞療法 / フィラデルフィア染色体 / チロシンキナーゼ阻害薬 / 急性リンパ性白血病 / 細胞免疫療法 / がん Less
  • Research Projects

    (4 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (2 People)
  •  Developing a combinatorial treatment of CAR-T therapy and liposome-based mRNA vaccination for pediatric solid tumorsPrincipal Investigator

    • Principal Investigator
      齋藤 章治
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Shinshu University
  •  Tumor-tropic liposome-mediated therapeutic delivery of mRNA for the treatment of adolescent and young adult cancers.Principal Investigator

    • Principal Investigator
      Saito Shoji
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Shinshu University
  •  Combining oncolytic virus with genetically modified T cell therapy for the treatment of cancerPrincipal Investigator

    • Principal Investigator
      Saito Shoji
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Shinshu University
  •  PiggyBac transposon-mediated CD19-specific T cells against Ph+ acute lymphoblastic leukemiaPrincipal Investigator

    • Principal Investigator
      SAITO Shoji
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Shinshu University

All 2022 2021 2020 2014 2012

All Journal Article Presentation

  • [Journal Article] Non-viral inducible caspase 9 mRNA delivery using lipid nanoparticles against breast cancer: An in-vitro study2022

    • Author(s)
      Nakashima Ikumi、Saito Shoji、Akahoshi Eiichi、Yagyu Shigeki、Sugano-Ishihara Mitsuko、Nakazawa Yozo
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 635 Pages: 144-153

    • DOI

      10.1016/j.bbrc.2022.09.105

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07641, KAKENHI-PROJECT-20K08227
  • [Journal Article] AMLに対する抗体・免疫細胞療法の動向2022

    • Author(s)
      齋藤章治 中沢洋三
    • Journal Title

      血液内科

      Volume: 85 Pages: 814-821

    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Journal Article] Investigation of risk factors associated with erythrocyte engraftment after ABO-incompatible hematopoietic stem cell transplantation2021

    • Author(s)
      Yanagisawa R, Nakazawa H, Nishina S, Saito S, Shigemura T, Tanaka M, Nakazawa Y.
    • Journal Title

      Clin Transplant

      Volume: 27-Mar Issue: 6

    • DOI

      10.1111/ctr.14300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Journal Article] Thyroid tumor surveillance using ultrasound in childhood cancer survivors2020

    • Author(s)
      Furui Y, Morita D, Okura E, Komori K, Saito S, Hirabayashi K, Tanaka M, Nakazawa Y.
    • Journal Title

      Pediatr Int

      Volume: May;62(5) Issue: 5 Pages: 562-568

    • DOI

      10.1111/ped.14179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Journal Article] Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation2020

    • Author(s)
      Shigemura T, Sakashita K, Okura E, Morita D, Komori K, Kurata T, Hirabayashi K, Saito S, Tanaka M, Yanagisawa R, Nakazawa Y. Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation
    • Journal Title

      Int J Hematol

      Volume: 111 Issue: 5 Pages: 702-710

    • DOI

      10.1007/s12185-020-02826-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10021, KAKENHI-PROJECT-17K10104, KAKENHI-PROJECT-17K10105, KAKENHI-PROJECT-20K08227
  • [Journal Article] Delayed methotrexate clearance and acute kidney injury after high-dose methotrexate chemotherapy concurrent with dasatinib in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia: A case report2020

    • Author(s)
      Morota H, Saito S, Uchida E, Okura E, Matsuoka D, Hidaka Y, Natsume T, Watanabe T, Shigemura T, Morita D, Tanaka M, Kurata T, Sakashita K, Nakazawa Y.
    • Journal Title

      Pediatr Blood Cancer

      Volume: Apr;67(4) Issue: 4

    • DOI

      10.1002/pbc.28173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Journal Article] Assessment of kidney function using inulin-based and estimated glomerular filtration rates before and after allogeneic hematopoietic stem cell transplantation in pediatric patients2020

    • Author(s)
      Matsuoka D, Hirabayashi K, Murase T, Saito S, Hidaka Y, Nakazawa Y.
    • Journal Title

      Pediatr Blood Cancer

      Volume: Dec;67(12) Issue: 12

    • DOI

      10.1002/pbc.28733

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Journal Article] Complete measurable residual disease response after combination chemotherapy with AML-type and ALL-type regimens in pediatric B/myeloid acute bilineal leukemia2020

    • Author(s)
      Saito S, Taira C, Matsuda K, Yanagisawa R, Morita D, Shigemura T, Yoshikawa K, Tanaka M, Sakashita K, Mukai S, Shimodaira S, Koike K, Nakazawa Y
    • Journal Title

      Leuk Lymphoma

      Volume: 61 Issue: 4 Pages: 967-970

    • DOI

      10.1080/10428194.2019.1697813

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10021, KAKENHI-PROJECT-20K08227
  • [Journal Article] Autologous non-human primate model for safety assessment of piggyBac transposon-mediated chimeric antigen receptor T cells on granulocyte-macrophage colony-stimulating factor receptor.2020

    • Author(s)
      Morokawa H, Yagyu S, Hasegawa A, Tanaka M, Saito S, Mochizuki H, Sakamoto K, Shimoi A, Nakazawa Y.
    • Journal Title

      Clinical & Translational Immunology

      Volume: 22 Issue: 11

    • DOI

      10.1002/cti2.1207

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08326, KAKENHI-PROJECT-20K07641, KAKENHI-PROJECT-20K08227
  • [Journal Article] Transfusion outcome for volume- and plasma-reduced platelet concentrates for pediatric patients2020

    • Author(s)
      Tanaka M, Yanagisawa R, Yamanaka M, Konno S, Takemura K, Kojima S, Okura E, Morita D, Saito S, Komori K, Matsuzawa H, Sakashita K, Tozuka M, Nakazawa Y.
    • Journal Title

      Transfus Apher Sci

      Volume: Aug;59(4) Issue: 4 Pages: 102776-102776

    • DOI

      10.1016/j.transci.2020.102776

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Journal Article] Anti-leukemic potency of piggyBac-mediated CD19-specificT cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia2014

    • Author(s)
      Shoji Saito, Yozo Nakazawa, Miyuki Tanaka, Ryu Yanagisawa, Akane Sueki, Kazuyuki Matsuda, Yasuhiro Maeda, Yuko Sato, Seiichi Okabe, Takeshi Inukai, Kanji Sugita, Matthew H. Wilson, Cliona M. Rooney, and Kenichi Koike
    • Journal Title

      Cytotherapy

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791050
  • [Presentation] Non-Viral Delivery of Therapeutic mRNA Using Tumor-Tropic Liposomes for the Treatment of Solid Tumors2021

    • Author(s)
      Saito S, Nakashima I, Akahoshi E, Ishihara-Sugano M, Yagyu S, Nakazawa Y.
    • Organizer
      American Society of Gene and Cell Therapy 24th Annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Presentation] 難治性血液腫瘍に対する遺伝子・細胞治療の開発2021

    • Author(s)
      齋藤章治
    • Organizer
      第124回日本小児科学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Presentation] Tumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies2020

    • Author(s)
      Saito, S; Nakashima, I; Hasegawa, A; Akahoshi, E; Ishihara-Sugano, M; Yagyu, S; Nakazawa, Y
    • Organizer
      23rd Annual Meeting of the American Society for Gene and Cell Therapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Presentation] Tumor-Tropic Liposome-Based Delivery of Therapeutic mRNA for T Cell Leukemias2020

    • Author(s)
      Saito, S; Nakashima, I; Hasegawa, A; Akahoshi, E; Sugano, M; Yagyu, S; Nakazawa, Y
    • Organizer
      第62回日本小児血液・がん学会
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Presentation] Tumor-tropic liposome-mediated therapeutic delivery of mRNA for pediatric / adolescent and young adult cancers.2020

    • Author(s)
      Saito, S; Nakashima, I; Hasegawa, A; Akahoshi, E; Sugano, M; Yagyu, S; Nakazawa, Y
    • Organizer
      第79回日本癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Presentation] Tumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies2020

    • Author(s)
      Saito, S; Nakashima, I; Hasegawa, A; Akahoshi, E; Ishihara-Sugano, M; Yagyu, S; Nakazawa, Y
    • Organizer
      63rd ASH Annual Meeting & Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Presentation] Tumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies2020

    • Author(s)
      Shoji Saito, Ikumi Nakashima, Aiko Hasegawa, Eiichi Akahoshi, Mitsuko Ishihara-Sugano, Shigeki Yagyu, and Yozo Nakazawa
    • Organizer
      ASGCT 23rd Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15702
  • [Presentation] 1.Tumor-tropic liposome-mediated therapeutic delivery of mRNA for T cell malignancies2020

    • Author(s)
      Saito, S; Nakashima, I; Hasegawa, A; Akahoshi, E; Sugano, M; Yagyu, S; Nakazawa, Y
    • Organizer
      第82回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08227
  • [Presentation] Potency of piggyBac transposon-mediated CD19-specific T-cells against drug-resistant philadelphia chromosome-positive acute lymphoblastic leukemia2014

    • Author(s)
      S. Saito, Y. Nakazawa, M. Tanaka, R. Yanagisawa, A. Sueki, K. Matsuda, M.H. Wilson, C. Rooney, K. Koike
    • Organizer
      20t Annual International Society for Cellular Therapy (ISCT) Meeting
    • Place of Presentation
      Paris, France
    • Data Source
      KAKENHI-PROJECT-24791050
  • [Presentation] CD19-specific T-cell therapy for Ph+ALL using piggyBac transposon-based gene modification2012

    • Author(s)
      Shoji Saito, Yozo Nakazawa, Miyuki Tanaka, Ryu Yanagisawa, Kazuyuki Matsuda, Yasuhiro Maeda, Takeshi Inukai, Kanji Sugita, Kenichi Koike
    • Organizer
      日本血液学会
    • Place of Presentation
      京都市
    • Year and Date
      2012-10-20
    • Data Source
      KAKENHI-PROJECT-24791050
  • [Presentation] 薬剤耐性Ph陽性急性リンパ性白血病に対するpiggyBacトランスポゾン遺伝子改変CD19特異的T細胞療法の開発2012

    • Author(s)
      齋藤章治, 中沢洋三, 田中美幸, 柳沢龍, 松田和之, 前田裕弘, 犬飼岳史, 杉田完爾, 小池健一
    • Organizer
      小児血液がん学会
    • Place of Presentation
      横浜市
    • Year and Date
      2012-12-01
    • Data Source
      KAKENHI-PROJECT-24791050
  • [Presentation] CD19-specific T-cell therapy for refractory Philadelphia-chromosome-positive acute lymphoblastic leukemia using PiggyBac transposon-based gene modification and low autoserum-containing, but xeno-free and tumor cell line-free culture system2012

    • Author(s)
      Shoji Saito, Yozo Nakazawa, Miyuki Tanaka, Ryu Yanagisawa, Kazuyuki Matsuda, Yasuhiro Maeda, Takeshi Inukai, Kanji Sugita, Kenichi Koike
    • Organizer
      Annual Meetings of American Society of Gene Therapy
    • Place of Presentation
      Philadelphia, PA
    • Data Source
      KAKENHI-PROJECT-24791050
  • [Presentation] 難治性急性リンパ性白血病に対するCD19特異的遺伝子改変T細胞療法の開発2012

    • Author(s)
      齋藤章治, 中沢洋三, 平林耕一, 松田和之, 杉田完爾, 小池健一
    • Organizer
      日本小児科学会
    • Place of Presentation
      福岡市
    • Year and Date
      2012-04-21
    • Data Source
      KAKENHI-PROJECT-24791050
  • [Presentation] CD19-specific T-cell therapy for refractory Philadelphia-chromosome-positive acute lymphoblastic leukemia using PiggyBac transposon-based gene modification and low autoserum-containing, but xeno-free and tumor cell line-free culture system2012

    • Author(s)
      Shoji Saito, Yozo Nakazawa, Miyuki Tanaka, Ryu Yanagisawa, Yasuhiro Maeda, Takeshi Inukai, Kanji Sugita, Matthew H Wilson, Cliona M Rooney, and Kenichi Koike
    • Organizer
      Annual Meetings of American Society of Gene Therapy
    • Place of Presentation
      Philadelphia PA
    • Year and Date
      2012-05-18
    • Data Source
      KAKENHI-PROJECT-24791050
  • 1.  YAGYU Shigeki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 2.  柳沢 龍
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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