NISHIMURA Tatsunori 西村建徳

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西村建徳ニシムラタツノリ

Nishimura Tatsunori 西村建徳

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Researcher Number	10624869
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2023: 名古屋大学, 医学系研究科, 助教 2018 – 2020: 金沢大学, がん進展制御研究所, 助教 2017: 金沢大学, がん進展制御研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor therapeutics
Keywords	Principal Investigator ミトコンドリア / 葉酸代謝 / 葉酸代謝経路 / 腫瘍原生能 / 葉酸代謝酵素 / エピゲノム / がん転移 / 微小環境 / 乳がん / がん / 幹細胞様形質

Identification of mechanisms of metastasis mediated by the inhibiton of mitochondrial enzymes of one-carbon metabolismPrincipal Investigator
- Principal Investigator
  
  西村建徳
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Nagoya University
Analyisis of cancer microenvironment under inhibition of enzymes of mitochondrial one-carbon metabolismPrincipal Investigator
- Principal Investigator
  
  Nishimura Tatsunori
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Evaluation of efficacy for targeting enzymes of mitochondrial one-carbon metabolism for cancer treatment.Principal Investigator
- Principal Investigator
  
  Nishimura Tatsunori
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kanazawa University

All 2023 2018 2017 Other

All Journal Article Presentation Book Other

[Book] がん代謝　ワールブルグを超えて全容解明に挑む2017
- Author(s)
  西村建徳、後藤典子　曽我朋義／編
- Total Pages
  6
- Publisher
  羊土社
- ISBN
  9784758103633
- Data Source
  KAKENHI-PROJECT-17K15021
[Journal Article] Mitochondrial one-carbon metabolic enzyme MTHFD2 facilitates mammary gland development during pregnancy2023
- Author(s)
  Wang Yuming、Hongu Tsunaki、Nishimura Tatsunori、Takeuchi Yasuto、Takano Hiroshi、Daikoku Takiko、Yao Ryoji、Gotoh Noriko
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 674 Pages: 183-189
- DOI
  10.1016/j.bbrc.2023.06.074
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18237, KAKENHI-PROJECT-21K15501, KAKENHI-PROJECT-23K06610, KAKENHI-PROJECT-23K06630, KAKENHI-PROJECT-22K20818, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H02761
[Journal Article] TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.2023
- Author(s)
  Suzuki Miho M.、Iijima Kenta、Ogami Koichi、Shinjo Keiko、Murofushi Yoshiteru、Xie Jingqi、Wang Xuebing、Kitano Yotaro、Mamiya Akira、Kibe Yuji、Nishimura Tatsunori、Ohka Fumiharu、Saito Ryuta、Sato Shinya、Kobayashi Junya、Yao Ryoji、Miyata Kanjiro、Kataoka Kazunori、Suzuki Hiroshi I.、Kondo Yutaka.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 4521-4521
- DOI
  10.1038/s41467-023-40243-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20598, KAKENHI-PROJECT-19KK0209, KAKENHI-PROJECT-19K07661, KAKENHI-PROJECT-20K07570, KAKENHI-PROJECT-22K06925, KAKENHI-PROJECT-23K06610, KAKENHI-PROJECT-23K06633, KAKENHI-PROJECT-20K12162, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27438
[Journal Article] Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD22018
- Author(s)
  Nishimura Tatsunori、Nakata Asuka、Chen Xiaoxi、Nishi Kurumi、Meguro-Horike Makiko、Sasaki Soichiro、Kita Kenji、Horike Shin-ichi、Saitoh Kaori、Kato Keiko、Igarashi Kaori、Murayama Takahiko、Kohno Susumu、Takahashi Chiaki、Mukaida Naofumi、Yano Seiji、Soga Tomoyoshi、Tojo Arinobu、Gotoh Noriko
- Journal Title
  
  Oncogene
  
  Volume: 38 Issue: 14 Pages: 2464-2481
- DOI
  10.1038/s41388-018-0589-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K19587, KAKENHI-PROJECT-17K14992, KAKENHI-PROJECT-17K15021, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-17H03576
[Presentation] Downregulation of MTHFD2, an enzyme of one-carbon metabolism in mitochondria, inhibits tumor growth and cancer stem-like properties.2018
- Author(s)
  西村建徳
- Organizer
  The 11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Precision Medicine
- Data Source
  KAKENHI-PROJECT-17K15021
[Presentation] ミトコンドリア葉酸代謝酵素のがん幹細胞様形質と薬剤耐性への寄与2018
- Author(s)
  西村建徳
- Organizer
  第77回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15021
[Presentation] 葉酸代謝酵素、MTHFD2ノックダウンによる幹細胞形質の減弱2018
- Author(s)
  西村建徳
- Organizer
  第2回がん三次元培養研究会
- Data Source
  KAKENHI-PROJECT-17K15021
[Presentation] Cancer Stem-ike Properties And Drug Resistance Are Dependent On The Purine Synthetic Metabolism Mediated By The Mitochondrial Enzyme2018
- Author(s)
  西村建徳
- Organizer
  The 6th JCA-AACR Special Joint Conference
- Data Source
  KAKENHI-PROJECT-17K15021
[Presentation] 乳がんにおけるMTHFD1Lの役割2017
- Author(s)
  西村和記、西村建徳、後藤典子
- Organizer
  第21回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-17K15021
[]

1. Nakata Asuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Nishi Kurumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. Meguro Makiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Sasaki Soichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Kita Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Horike Shin-ichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Saito Kaori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Kato Keiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Igarashi Kaori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Murayama Takahiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Kohno Susumu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Takahashi Chiaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. Mukaida Naofumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Yano Seiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Soga Tomoyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. Tojo Arinobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Gotoh Noriko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. Chen Xiaoxi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 近藤豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 飯島健太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NISHIMURA Tatsunori 西村 建徳

西村 建徳 ニシムラ タツノリ

Nishimura Tatsunori 西村 建徳

Research Projects

Research Products

Co-Researchers

Identification of mechanisms of metastasis mediated by the inhibiton of mitochondrial enzymes of one-carbon metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyisis of cancer microenvironment under inhibition of enzymes of mitochondrial one-carbon metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of efficacy for targeting enzymes of mitochondrial one-carbon metabolism for cancer treatment.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] がん代謝 ワールブルグを超えて全容解明に挑む2017

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Mitochondrial one-carbon metabolic enzyme MTHFD2 facilitates mammary gland development during pregnancy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD22018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Downregulation of MTHFD2, an enzyme of one-carbon metabolism in mitochondria, inhibits tumor growth and cancer stem-like properties.2018

Author(s)

Organizer

Data Source

[Presentation] ミトコンドリア葉酸代謝酵素のがん幹細胞様形質と薬剤耐性への寄与2018

Author(s)

Organizer

Data Source

[Presentation] 葉酸代謝酵素、MTHFD2ノックダウンによる幹細胞形質の減弱2018

Author(s)

Organizer

Data Source

[Presentation] Cancer Stem-ike Properties And Drug Resistance Are Dependent On The Purine Synthetic Metabolism Mediated By The Mitochondrial Enzyme2018

Author(s)

Organizer

Data Source

[Presentation] 乳がんにおけるMTHFD1Lの役割2017

Author(s)

Organizer

Data Source

[]

NISHIMURA Tatsunori 西村建徳

西村建徳ニシムラタツノリ

Nishimura Tatsunori 西村建徳

[Book] がん代謝　ワールブルグを超えて全容解明に挑む2017