KONUMA TUYOSHI 小沼剛

… Alternative Names

TSUYOSHI Konuma 小沼剛

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Researcher Number	10631682
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 生命医科学研究科, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 横浜市立大学, 生命医科学研究科, 助教 2013 – 2014: 公益財団法人サントリー生命科学財団, その他部局等, 研究員
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related / Biophysics Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator NMR / エンベロープタンパク質 / 阻害剤 / ブロモドメイン / ETドメイン / BRD4 / Eタンパク質 / SARS-CoV-2 / COVID-19 / 溶媒のpH / 蛋白質の精製 / 非特異的DNA結合 … More Except Principal Investigator … More ショウジョウバエ / 膵がん / 表現型スクリーニング / 個別化医療 / 新規治療法 / 膵臓がん / ショウジョウバエモデル / 新規治療法の開発 / リボフラビン / 新規治療法開発 / 薬物抵抗性 / 遺伝学 / 頑健性 / 治療抵抗性 / キナーゼ / モデル動物 Less

遺伝子型に立脚した膵がん個別化医療開発基盤の創出
- Principal Investigator
  
  園下将大
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hokkaido University
Drug development for COVID-19 targeting BRD4Principal Investigator
- Principal Investigator
  
  小沼剛
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Yokohama City University
Indentifying the basis for the robustness in pancreatic cancer to develop novel therapeuitics
- Principal Investigator
  
  Sonoshita Masahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hokkaido University
Developing a novel therapy for pancreatic cancer targeting the riboflavin pathway
- Principal Investigator
  
  Ooshio Takako
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hokkaido University
Elucidation of the nonspecific DNA-binding mechanism of Oct3/4 using NMRPrincipal Investigator
- Principal Investigator
  
  TSUYOSHI Konuma
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Suntory Foundation for Life Sciences

All 2024 2014 2013 Other

All Journal Article Presentation

[Journal Article] Distinct Histone H3 Lysine 27 Modifications Dictate Different Outcomes of Gene Transcription2024
- Author(s)
  Konuma Tsuyoshi、Zhou Ming-Ming
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 436 Issue: 7 Pages: 168376-168376
- DOI
  10.1016/j.jmb.2023.168376
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05720
[Journal Article] Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin2014
- Author(s)
  Erik, W., Morimoto, D., Sugase, K., Konuma, T., Tochio, H., Shirakawa, M.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25840059
[Journal Article] Fast and accurate fitting of relaxation dispersion data using the flexible software package GLOVE2013
- Author(s)
  Sugase, K., Konuma, T., Lansing, J.C., Wright, P.E.
- Journal Title
  
  J. Biomol. NMR
  
  Volume: 56 Issue: 3 Pages: 275-283
- DOI
  10.1007/s10858-013-9747-5
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-25650056, KAKENHI-PROJECT-25840059
[Presentation] Elucidation of nonspecific DNA-binding mechanism by quantitative analysis of chemical shift changes2013
- Author(s)
  Konuma, T., Harada, E., Oda, T., Sato, M., Sugase, K.
- Organizer
  5th Asia-Pacific NMR Symposium in conjunction with ANZMAG
- Place of Presentation
  Brisbane Convention and Exhibition Centre
- Data Source
  KAKENHI-PROJECT-25840059
[Presentation] Extracting information on protein dynamics from crowded NMR spectra using relaxation dispersion difference
- Author(s)
  Konuma, T.
- Organizer
  The 10th Korea-Japan Bilateral Symposium on Biological NMR
- Place of Presentation
  Seoul National University
- Invited
- Data Source
  KAKENHI-PROJECT-25840059
[Presentation] Elucidation of the nonspecific DNA-binding mechanism of the POU homeodomain using NMR
- Author(s)
  Tsuyoshi Konuma
- Organizer
  Protein Society Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-07-27 – 2014-07-30
- Data Source
  KAKENHI-PROJECT-25840059

1. Sonoshita Masahiro (80511857)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 市川聡 (60333621)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. Ooshio Takako (80723238)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 藤井清永 (10278327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 五十嵐学 (10374240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 合田圭介 (70518696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 浴本亨 (90829821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 菅瀬謙治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KONUMA TUYOSHI 小沼 剛

TSUYOSHI Konuma 小沼 剛

Research Projects

Research Products

Co-Researchers

遺伝子型に立脚した膵がん個別化医療開発基盤の創出

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Drug development for COVID-19 targeting BRD4Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Indentifying the basis for the robustness in pancreatic cancer to develop novel therapeuitics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Developing a novel therapy for pancreatic cancer targeting the riboflavin pathway

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the nonspecific DNA-binding mechanism of Oct3/4 using NMRPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Distinct Histone H3 Lysine 27 Modifications Dictate Different Outcomes of Gene Transcription2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin2014

Author(s)

Journal Title

Data Source

[Journal Article] Fast and accurate fitting of relaxation dispersion data using the flexible software package GLOVE2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Elucidation of nonspecific DNA-binding mechanism by quantitative analysis of chemical shift changes2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Extracting information on protein dynamics from crowded NMR spectra using relaxation dispersion difference

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Elucidation of the nonspecific DNA-binding mechanism of the POU homeodomain using NMR

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

KONUMA TUYOSHI 小沼剛

TSUYOSHI Konuma 小沼剛