Ayabe Shinya 綾部信哉

Researcher Number	10633563
Other IDs	https://orcid.org/0000-0003-2737-5315
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, バイオリソース研究センター, 専任研究員
Affiliation (based on the past Project Information) *help	2019 – 2024: 国立研究開発法人理化学研究所, バイオリソース研究センター, 専任研究員 2018: 国立研究開発法人理化学研究所, バイオリソース研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related Except Principal Investigator Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 42040:Laboratory animal science-related / Basic Section 49030:Experimental pathology-related
Keywords	Principal Investigator ゲノム編集 / モデルマウス / サイトカイン / 肺がん / 線維芽細胞 / がん Except Principal Investigator 遺伝子改変マウス / ゲノム編集 / マウス / 疾患モデル … More / 必須遺伝子 / モデルマウス開発 / ランダムミュータジェネシス / マウスES細胞 / ランダム変異 / 4q / ４番染色体 / 疾患モデルマウス / ４番染色体長腕部分重複症 / モデルマウス / 遺伝子量補正 / トリソミー / 膜性骨化 / ４番染色体長腕部分重複 / 疾患モデル動物 / 遺伝子量効果 / 4番染色体長腕部分重複症 / 染色体異常 / 遺伝子量バランス / ヒト4番染色体長腕部分重複症 / 染色体異常疾患 / Hand2 / イメージング / 遺伝子発現イメージング / 軟骨イメージング / 造影X線CT / X線イメージング / CT / X線 / 遺伝子発現 / 軟骨 / 形態イメージング Less

新規direct-cKOシステムでの必須遺伝子探索とその網羅的解析基盤の構築
- Principal Investigator
  
  水野聖哉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  University of Tsukuba
Mutagenesis of non-coding regions via excisional genome editing
- Principal Investigator
  
  Mizuno Seiya
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  University of Tsukuba
Analysis of the dosage balance of genes in human chromosomal disorders
- Principal Investigator
  
  Tamura Masaru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Institute of Physical and Chemical Research
Development of the new imaging method to visualize the gene expression patterns and cartilage using the X-ray CT
- Principal Investigator
  
  TAMURA MASARU
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Institute of Physical and Chemical Research
Role of prostaglandin D2 on lung cancer microenvironment through cancer-assisted fibroblastsPrincipal Investigator
- Principal Investigator
  
  Ayabe Shinya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Institute of Physical and Chemical Research

All 2021 2020 2019

All Journal Article

[Journal Article] Mouse resources at the RIKEN BioResource Research Center and the National BioResource Project core facility in Japan2021
- Author(s)
  Mizuno-Iijima Saori、Nakashiba Toshiaki、Ayabe Shinya、Nakata Hatsumi、Ike Fumio、Hiraiwa Noriko、Mochida Keiji、Ogura Atsuo、Masuya Hiroshi、Kawamoto Shoko、Tamura Masaru、Obata Yuichi、Shiroishi Toshihiko、Yoshiki Atsushi
- Journal Title
  
  Mammalian Genome
  
  Volume: 33 Issue: 1 Pages: 181-191
- DOI
  10.1007/s00335-021-09916-x
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05758, KAKENHI-PROJECT-19H03457
[Journal Article] Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes.2020
- Author(s)
  Matsumura K, (33名中略）, Hashimoto R, (37名中35番目）,Hashimoto H, Nakazawa T.
- Journal Title
  
  Nat. Commun
  
  Volume: 11(1) Issue: 1 Pages: 859-859
- DOI
  10.1038/s41467-020-14697-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0022, KAKENHI-PROJECT-19K22471, KAKENHI-PROJECT-19H05467, KAKENHI-PUBLICLY-19H04758, KAKENHI-PUBLICLY-19H04909, KAKENHI-PUBLICLY-19H05218, KAKENHI-PROJECT-17H02217, KAKENHI-PROJECT-17H04014, KAKENHI-PROJECT-18H02574, KAKENHI-PROJECT-19H03457, KAKENHI-PROJECT-19H04062, KAKENHI-PROJECT-17J00152, KAKENHI-PROJECT-16K07004, KAKENHI-PROJECT-17K10300, KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-18K14919, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K07945, KAKENHI-PLANNED-18H05416, KAKENHI-PROJECT-17H03989, KAKENHI-PUBLICLY-19H05217, KAKENHI-PROJECT-20H03414, KAKENHI-PROJECT-18K19276, KAKENHI-PROJECT-20H00492, KAKENHI-PROJECT-20H03855
[Journal Article] Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation2019
- Author(s)
  Gurumurthy Channabasavaiah B.、O’Brien Aidan R.、Quadros Rolen M.、Adams John、Alcaide Pilar、Ayabe Shinya、Ballard Johnathan、Batra Surinder K.、Beauchamp Marie-Claude、Becker Kathleen A.、Bernas Guillaume、Ohtsuka Masato他
- Journal Title
  
  Genome Biology
  
  Volume: 20 Issue: 1 Pages: 171-171
- DOI
  10.1186/s13059-019-1776-2
- NAID
  120007127906
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11128, KAKENHI-PROJECT-19K09031, KAKENHI-PROJECT-18K15255, KAKENHI-PROJECT-19K16025, KAKENHI-PROJECT-18KK0251, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-17KT0126

1. TAMURA MASARU (50370119)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Mizuno Seiya (10633141)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 久野朗広 (60830122)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NAKAZAWA Takanobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 大塚正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 日野敏昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 小倉淳郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ayabe Shinya 綾部 信哉

Research Projects

Research Products

Co-Researchers

新規direct-cKOシステムでの必須遺伝子探索とその網羅的解析基盤の構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mutagenesis of non-coding regions via excisional genome editing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the dosage balance of genes in human chromosomal disorders

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the new imaging method to visualize the gene expression patterns and cartilage using the X-ray CT

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of prostaglandin D2 on lung cancer microenvironment through cancer-assisted fibroblastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Mouse resources at the RIKEN BioResource Research Center and the National BioResource Project core facility in Japan2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation2019

Author(s)

Journal Title

DOI

NAID

Data Source

Ayabe Shinya 綾部信哉