Nakahama Taisuke 中濱泰祐

… Alternative Names

中濱泰祐ナカハマタイスケ

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Researcher Number	10636187
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 大学院医学系研究科, 助教 2022 – 2023: 大阪大学, 大学院医学系研究科, 助教 2016 – 2021: 大阪大学, 医学系研究科, 助教 2015: 大阪大学, 医学(系)研究科(研究院), 特別研究員(PD) 2013: 大阪大学, 学内共同利用施設等, その他 2012: 大阪大学, 免疫学フロンティア研究センター, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / Immunology
Keywords	Principal Investigator RNA編集 / 自己免疫疾患 / エカルディ・グティエール症候群 / MDA5 / 脳症 / AGS / ADAR1 / 獲得免疫 / Adar1 / T細胞成熟 … More / RNA編集酵素 / T細胞 / autoimmune disease / AHR / Th17 / microRNA Less

細胞間ネットワークに着眼した遺伝性自己炎症疾患における白質脳症病態の理解Principal Investigator
- Principal Investigator
  
  中濱泰祐
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  The University of Osaka
Elucidation of the pathogenesis of genetic encephalopathy caused by defects in RNA editingPrincipal Investigator
- Principal Investigator
  
  Nakahama Taisuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Osaka University
Elucidation of the mechanism underlying the regulation of adaptive immunity by endogenous double-stranded RNAPrincipal Investigator
- Principal Investigator
  
  Nakahama Taisuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Osaka University
The role of RNA editing in Th17 cell differentiationPrincipal Investigator
- Principal Investigator
  
  Nakahama Taisuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
AhrによるmicroRNAの発現調節を介したTh17細胞の分化制御機構の解析Principal Investigator
- Principal Investigator
  
  中濱泰祐
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2012

All Journal Article Presentation

[Journal Article] RNA編集酵素ADAR1による二本鎖RNAセンサーシステムの制御2023
- Author(s)
  中濱泰祐
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 第80巻第5号 Pages: 599-599
- Data Source
  KAKENHI-PROJECT-21K07080
[Journal Article] RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing2023
- Author(s)
  Xing Yanfang、Nakahama Taisuke、Wu Yuke、Inoue Maal、Kim Jung In、Todo Hiroyuki、Shibuya Toshiharu、Kato Yuki、Kawahara Yukio
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 7 Pages: 104840-104840
- DOI
  10.1016/j.jbc.2023.104840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K12109, KAKENHI-PROJECT-21K07080, KAKENHI-PROJECT-23K27267
[Journal Article] ウイルス感染症におけるRNA編集の役割2023
- Author(s)
  中濱泰祐, 河原行郎
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 第80巻第4号 Pages: 427-427
- Data Source
  KAKENHI-PROJECT-21K07080
[Journal Article] RNA制御とI型インターフェロノパシー2022
- Author(s)
  中濱泰祐、河原行郎
- Journal Title
  
  実験医学
  
  Volume: Vol.40 No.15 Pages: 2505-2512
- Data Source
  KAKENHI-PROJECT-21K07080
[Journal Article] RNAのイノシン化修飾の破綻はエカルディ・グティエール症候群様症状をひき起こす2022
- Author(s)
  中濱泰祐、河原行郎
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 第77巻第6号 Pages: 737-743
- Data Source
  KAKENHI-PROJECT-21K07080
[Journal Article] The RNA-editing enzyme ADAR1: a regulatory hub that tunes multiple dsRNA-sensing pathways2022
- Author(s)
  Nakahama Taisuke、Kawahara Yukio
- Journal Title
  
  International Immunology
  
  Volume: 35 Issue: 3 Pages: 123-133
- DOI
  10.1093/intimm/dxac056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07080, KAKENHI-PROJECT-20H03341
[Journal Article] Deciphering the Biological Significance of ADAR1-Z-RNA Interactions2021
- Author(s)
  Nakahama Taisuke、Kawahara Yukio
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 21 Pages: 11435-11435
- DOI
  10.3390/ijms222111435
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03341, KAKENHI-PROJECT-21K07080
[Journal Article] An Aicardi-Goutieres Syndrome-Causative Point Mutation in Adar1 Gene Invokes Multiorgan Inflammation and Late-Onset Encephalopathy in Mice2021
- Author(s)
  Inoue Maal、Nakahama Taisuke、Yamasaki Ryuichiro、Shibuya Toshiharu、Kim Jung In、Todo Hiroyuki、Xing Yanfang、Kato Yuki、Morii Eiichi、Kawahara Yukio
- Journal Title
  
  The Journal of Immunology
  
  Volume: 207 Issue: 12 Pages: 3016-3027
- DOI
  10.4049/jimmunol.2100526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03341, KAKENHI-PROJECT-20J11266, KAKENHI-PROJECT-18K11526, KAKENHI-PROJECT-21K07080, KAKENHI-PROJECT-21K12109
[Journal Article] RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain.2021
- Author(s)
  Jung In Kim, Taisuke Nakahama, Ryuichiro Yamasaki, Pedro Henrique Costa Cruz, Tuangtong Vongpipatana, Maal Inoue, Nao Kanou, Yanfang Xing, Hiroyuki Todo, Toshiharu Shibuya, Yuki Kato, Yukio Kawahara.
- Journal Title
  
  PLoS Genet
  
  Volume: 未定(In Press)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15186
[Journal Article] Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutieres-syndrome-like encephalopathy2021
- Author(s)
  Nakahama Taisuke、Kato Yuki、Shibuya Toshiharu、Inoue Maal、Kim Jung In、Vongpipatana Tuangtong、Todo Hiroyuki、Xing Yanfang、Kawahara Yukio
- Journal Title
  
  Immunity
  
  Volume: 54 Issue: 9 Pages: 1976-1988
- DOI
  10.1016/j.immuni.2021.08.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03341, KAKENHI-PROJECT-20J11266, KAKENHI-PROJECT-18K11526, KAKENHI-PROJECT-21K07080, KAKENHI-PROJECT-21K12109
[Journal Article] Adenosine-to-inosine RNA editing in the immune system: friend or foe?2020
- Author(s)
  Nakahama Taisuke、Kawahara Yukio
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: - Issue: 15 Pages: 2931-2948
- DOI
  10.1007/s00018-020-03466-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15186
[Journal Article] A Comparative Analysis of ADAR Mutant Mice Reveals Site-Specific Regulation of RNA Editing2020
- Author(s)
  Pedro Henrique Costa Cruz, Yuki Kato, Taisuke Nakahama, Toshiharu Shibuya, Yukio Kawahara
- Journal Title
  
  RNA
  
  Volume: 26(4) Issue: 4 Pages: 454-469
- DOI
  10.1261/rna.072728.119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22580, KAKENHI-PROJECT-18K15186, KAKENHI-PROJECT-18K11526
[Journal Article] ADAR1 Regulates Early T Cell Development via MDA5-Dependent and -Independent Pathways2020
- Author(s)
  Vongpipatana T, Nakahama T, Shibuya T, Kato Y, Kawahara Y
- Journal Title
  
  The Jorunal of Immunology
  
  Volume: 204(8) Issue: 8 Pages: 2156-2168
- DOI
  10.4049/jimmunol.1900929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22580, KAKENHI-PROJECT-18K15186, KAKENHI-PROJECT-18J11733, KAKENHI-PROJECT-18K11526
[Journal Article] ADAR1-mediated RNA editing is required for thymic self-tolerance and prevention of autoimmunity2018
- Author(s)
  Taisuke Nakahama, Yuki Kato, Jung In Kim, Tuangtong Vongpipatana, Yutaka Suzuki, Carl Walkley and Yukio Kawahara
- Journal Title
  
  EMBO Reports
  
  Volume: 19 Issue: 12
- DOI
  10.15252/embr.201846303
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11526, KAKENHI-PROJECT-18K15186, KAKENHI-PROJECT-16H05320, KAKENHI-PROJECT-18J11733, KAKENHI-PROJECT-17K19352, KAKENHI-PROJECT-16H06279
[Journal Article] Expression of aryl hydrocarbon receptor, inflammatory cytokines, and incidence of rheumatoid arthritis in Vietnamese dioxin-exposed people.2017
- Author(s)
  Nguyen CH, Nakahama T, Dang TT, Chu HH, Van Hoang L, Kishimoto T, Nguyen NT.
- Journal Title
  
  J Immunotoxicol
  
  Volume: 14 Issue: 1 Pages: 196-203
- DOI
  10.1080/1547691x.2017.1377323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19126
[Journal Article] Millrine D, Haruhiko M, Tei M, Dubey P, Kishan N, Nakahama T, Gemechu Y, Ripley B, Kishimoto T.2016
- Author(s)
  Millrine D, Haruhiko M, Tei M, Dubey P, Kishan N, Nakahama T, Gemechu Y, Ripley B, Kishimoto T.
- Journal Title
  
  Int Immunol.
  
  Volume: 印刷中 Issue: 6 Pages: 307-315
- DOI
  10.1093/intimm/dxw005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J05768, KAKENHI-PROJECT-15K19126
[Presentation] RNA編集酵素ADAR1による自然免疫制御の新たな展開2023
- Author(s)
  中濱泰祐
- Organizer
  The 1st Kansai RNA club
- Invited
- Data Source
  KAKENHI-PROJECT-21K07080
[Presentation] Rgulatory mechanisms underlying ADAR1 p150-mediated RNA editing2022
- Author(s)
  Taisuke Nakahama
- Organizer
  ABZ Meeting 2022 (A, B and Z: The Structure, Function and Genetics of Z-DNA and Z-RNA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07080
[Presentation] ADAR1によるZ型RNAへの結合の破綻はエカルディ-グティエール症候群様脳症を引き起こす2022
- Author(s)
  中濱泰祐, 河原行郎
- Organizer
  RNAフロンティアミーティング2022
- Data Source
  KAKENHI-PROJECT-21K07080
[Presentation] An Aicardi-Goutieres syndrome-causative point mutation in Adar1 gene invokes multi-organ inflammation and late-onset encephalopathy in mice2022
- Author(s)
  Taisuke Nakahama and Yukio Kawahara
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07080
[Presentation] 自然免疫応答を引き起こすZ型RNAの同定2022
- Author(s)
  中濱泰祐
- Organizer
  OTRI RNA-FS部門第１回シンポジウム
- Data Source
  KAKENHI-PROJECT-21K07080
[Presentation] Immune regulation by RNA editing2022
- Author(s)
  Taisuke Nakahama
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07080
[Presentation] Disruption of Z-RNA-binding of ADAR1 induces Aicardi-Goutieres syndrome-like encephalopathy in mice2021
- Author(s)
  Taisuke Nakahama, Yukio Kawahara
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07080
[Presentation] Disruption of Z-RNA-binding of ADAR1 induces Aicardi-Goutieres syndrome-like encephalopathy in mice2021
- Author(s)
  Taisuke Nakahama, Yuki Kato, Toshiharu Shibuya, Maal Inoue, Jung In Kim, Tuangtong Vongpipatana, Hiroyuki Todo, Yanfang Xing, Yukio Kawahara
- Organizer
  第22回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-21K07080
[Presentation] ADAR1 regulates early T cell development via MDA5-dependent and -independent pathways2019
- Author(s)
  Taisuke Nakahama, Tuangtong Vogpipatana, Yuki Kato and Yukio Kawahara
- Organizer
  RNA 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] ADAR1 regulates early T cell development via MDA5-dependent and -independent pathways2019
- Author(s)
  Taisuke Nakahama, Tuangtong Vogpipatana, Toshiharu Shibuya, Yuki Kato Yukio Kawahara
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] ADAR1-mediated RNA editing is required for thymic self-tolerance and prevention of autoimmunity2019
- Author(s)
  Nakahama Taisuke
- Organizer
  第20回武田科学振興財団生命科学シンポジウム「RNAネオバイオロジー」
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] ADAR1-mediated RNA editing is required for thymic self-tolerance and inhibition of autoimmunity2019
- Author(s)
  Nakahama Taisuke
- Organizer
  Gordon Research Seminar for RNA editing (イタリア)（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] 中枢性免疫寛容成立におけるRNA編集の役割の解明2018
- Author(s)
  中濱泰祐
- Organizer
  「先進ゲノム支援」2018年度拡大班会議
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] T細胞成熟におけるRNA編集の役割の解明2018
- Author(s)
  中濱泰祐
- Organizer
  先進ゲノム支援　2017年度拡大班会議
- Data Source
  KAKENHI-PROJECT-15K19126
[Presentation] ADAR1によるRNA編集を介した自己免疫制御機構2018
- Author(s)
  中濱泰祐
- Organizer
  第11回若手フォーラム
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] RNA editing-mediated prevention of activating MDA5 pathway is required for early T cell development2017
- Author(s)
  Taisuke Nakahama, Carl Walkley, Yukio Kawahara
- Organizer
  Gordon Research Conferences - 2017 Meeting - RNA editing
- Place of Presentation
  Ventura, California, United States
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19126
[Presentation] RNA editing-mediated prevention of activating MDA5 pathway is required for e arly T cell development2017
- Author(s)
  Taisuke Nakahama, Carl Walkley and Yukio Kawahara
- Organizer
  The 43rd Naito Conference
- Data Source
  KAKENHI-PROJECT-15K19126
[Presentation] RNA editing-mediated prevention of activating MDA5 pathway is required for early T cell development2017
- Author(s)
  Taisuke Nakahama, Carl Walkley and Yukio Kawahara
- Organizer
  RNAフロンティアミーティング 2017
- Data Source
  KAKENHI-PROJECT-15K19126
[Presentation] RNA editing-mediated prevention of activating MDA5 pathway is required for early T cell development2016
- Author(s)
  Taisuke Nakahama, Carl Walkley, Yukio Kawahara
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19126
[Presentation] AHR-mediated induction of miR-132/212 cluster enhances TH17 cell differentiation2012
- Author(s)
  Taisuke Nakahama
- Organizer
  日本免疫学会学術集会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24890107

1. KATO Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
2. 河原行郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

Nakahama Taisuke 中濱 泰祐

中濱 泰祐 ナカハマ タイスケ

Research Projects

Research Products

Co-Researchers

細胞間ネットワークに着眼した遺伝性自己炎症疾患における白質脳症病態の理解Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of genetic encephalopathy caused by defects in RNA editingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism underlying the regulation of adaptive immunity by endogenous double-stranded RNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of RNA editing in Th17 cell differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

AhrによるmicroRNAの発現調節を介したTh17細胞の分化制御機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] RNA編集酵素ADAR1による二本鎖RNAセンサーシステムの制御2023

Author(s)

Journal Title

Data Source

[Journal Article] RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ウイルス感染症におけるRNA編集の役割2023

Author(s)

Journal Title

Data Source

[Journal Article] RNA制御とI型インターフェロノパシー2022

Author(s)

Journal Title

Data Source

[Journal Article] RNAのイノシン化修飾の破綻はエカルディ・グティエール症候群様症状をひき起こす2022

Author(s)

Journal Title

Data Source

[Journal Article] The RNA-editing enzyme ADAR1: a regulatory hub that tunes multiple dsRNA-sensing pathways2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deciphering the Biological Significance of ADAR1-Z-RNA Interactions2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An Aicardi-Goutieres Syndrome-Causative Point Mutation in Adar1 Gene Invokes Multiorgan Inflammation and Late-Onset Encephalopathy in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain.2021

Author(s)

Journal Title

Data Source

[Journal Article] Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutieres-syndrome-like encephalopathy2021

Author(s)

Journal Title

DOI

Data Source

Nakahama Taisuke 中濱泰祐

中濱泰祐ナカハマタイスケ