Itou Junji 伊東潤二

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ITOU Junji 伊東潤二

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Researcher Number	10638844
Other IDs	https://orcid.org/0000-0001-8436-2209
Affiliation (Current)	2025: 国立研究開発法人国立循環器病研究センター, 研究所, 非常勤研究員
Affiliation (based on the past Project Information) *help	2021 – 2025: 国立研究開発法人国立循環器病研究センター, 研究所, 非常勤研究員 2019 – 2020: 公益財団法人神戸医療産業都市推進機構, その他部局等, 研究員 2014: 京都大学, 医学(系)研究科(研究院), 特定助教 2013 – 2014: 京都大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor diagnostics Except Principal Investigator Basic Section 44040:Morphology and anatomical structure-related
Keywords	Principal Investigator 乳腺 / 初期乳がん / エストロゲン / 乳がん / 老化 / 増殖開始 / NAD / 疾患モデル / 女性ホルモン / 乳管の異形成 … More / マウス / 発がん / 動物モデル / イソフラボン / E2 / Myc / 発酵大麦エキス / 微小浸潤 / 異形成 / 乳癌 / 乳がん予防 / マウスモデル / 遺伝学 / 分子生物学 / 細胞生物学 / 幹細胞 / 増殖 / 移動 / 細胞 / 細胞運動 / 細胞増殖 / 幹細胞転写因子 / Basal-like乳癌 / 運動能 / 増殖能 / 転写因子 / 癌細胞 … More Except Principal Investigator 上皮細胞 / ガス交換組織 / 生体イメージング / 血管内皮細胞 Less

生体内でのNAD+量低下による初期乳がん増殖開始のメカニズムの解明Principal Investigator
- Principal Investigator
  
  伊東潤二
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cardiovascular Center Research Institute
Analses of the formation of oxygen exchange niche through endothelial-epithelial interaction
- Principal Investigator
  
  中嶋洋行
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  National Cardiovascular Center Research Institute
妊娠経験の乳がん予防効果のメカニズムの解明Principal Investigator
- Principal Investigator
  
  伊東潤二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cardiovascular Center Research Institute
Establishment of novel mouse early breast cancer induction model for studies of breast tumorigenesis and preventionPrincipal Investigator
- Principal Investigator
  
  Itou Junji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cardiovascular Center Research Institute
  Foundation for Biomedical Research and Innovation at Kobe
Classification and characterization of a novel basal-like breast cancer group.Principal Investigator
- Principal Investigator
  
  ITOU Junji
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kyoto University

All 2021 2020 2019 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Supplementation with Fermented Barley Extract Prevents Mammary Epithelial Cell Invasion in an Early Breast Cancer Model2021
- Author(s)
  Itou Junji、Nakamura Akihiro、Hokazono Hideki、Toi Masakazu
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 54 Issue: 2 Pages: 73-78
- DOI
  10.1267/ahc.20-00029
- NAID
  130008031005
- ISSN
  0044-5991, 1347-5800
- Year and Date
  2021-04-28
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07665
[Journal Article] Eribulin mesylate-induced c-Fos upregulation enhances cell survival in breast cancer cell lines2020
- Author(s)
  Tanaka Sunao、Ishii Tomoko、Sato Fumiaki、Toi Masakazu、Itou Junji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 526 Issue: 1 Pages: 154-157
- DOI
  10.1016/j.bbrc.2020.03.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07665, KAKENHI-PROJECT-19K09063
[Journal Article] Estrogen Induces Mammary Ductal Dysplasia via the Upregulation of Myc Expression in a DNA-Repair-Deficient Condition2020
- Author(s)
  Itou Junji、Takahashi Rei、Sasanuma Hiroyuki、Tsuda Masataka、Morimoto Suguru、Matsumoto Yoshiaki、Ishii Tomoko、Sato Fumiaki、Takeda Shunichi、Toi Masakazu
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 2 Pages: 100821-100821
- DOI
  10.1016/j.isci.2020.100821
- NAID
  120006779803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07665, KAKENHI-PROJECT-19K09063, KAKENHI-PUBLICLY-18H04900, KAKENHI-PROJECT-19H04267, KAKENHI-PROJECT-18K18200
[Journal Article] An optical labeling-based proliferation assay system reveals the paracrine effect of interleukin-6 in breast cancer.2015
- Author(s)
  Itou J, Tanaka S, Sato F, Akiyama R, Kawakami Y, Toi M.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1853 Issue: 1 Pages: 27-40
- DOI
  10.1016/j.bbamcr.2014.10.004
- NAID
  120005512254
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390301, KAKENHI-PROJECT-25870384
[Journal Article] Function of the Developmental Transcription Factor SALL4 in Cancer2014
- Author(s)
  Junji Itou, Masakazu Toi
- Journal Title
  
  Journal of Carcinogenesis and Mutagenesis
  
  Volume: 5 Issue: 02 Pages: 159-159
- DOI
  10.4172/2157-2518.1000159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870384
[Journal Article] Sal-like 4 (SALL4) suppresses CDH1 expression and maintains cell dispersion in basal-like breast cancer2013
- Author(s)
  Junji Itou, Yoshiaki Matsumoto, Kiyotsugu Yoshikawa, Masakazu Toi
- Journal Title
  
  FEBS Letters
  
  Volume: 587 Issue: 18 Pages: 3115-3121
- DOI
  10.1016/j.febslet.2013.07.049
- NAID
  120005512255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870384
[Presentation] 新規の乳癌誘導系による発癌メカニズムおよび超初期乳癌の研究2020
- Author(s)
  伊東潤二
- Organizer
  第1回日本癌学会若手の会
- Data Source
  KAKENHI-PROJECT-19K07665
[Presentation] Tumor promoting effect of macrophages in a mouse early breast cancer model2020
- Author(s)
  伊東潤二
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07665
[Presentation] エストロゲンによる初期乳癌発生のメカニズムの解明2020
- Author(s)
  伊東潤二、佐藤史顕、戸井雅和
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07665
[Presentation] Estrogen induces mammary ductal dysplasia via up-regulation of Myc expression.2019
- Author(s)
  伊東潤二、高橋玲、松本純明、佐藤史顕、武田俊一、戸井雅和
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07665
[Presentation] 乳癌において SALL4 が制御する遺伝子群の解析2014
- Author(s)
  伊東潤二、松本純明、吉川清次、戸井雅和
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25870384
[Presentation] Analysis of slow-cycling cancer stem cell via an optical labeling-based proliferation assay system in basal-like breast cancer
- Author(s)
  Sunao Tanaka, Junji Itou, Wenzhao Li, Fumiaki Sato, Masakazu Toi
- Organizer
  EMBL Symposia, Frontiers in Stem Cells & Cancer
- Place of Presentation
  Heidelberg, Germany
- Year and Date
  2015-03-29 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-25870384
[Presentation] Activation of motility by SALL4-regulated integrin expression in basal-like breast cancer
- Author(s)
  Junji Itou, Sunao Tanaka, Fumiaki Sato, Masakazu Toi
- Organizer
  EMBL Symposia, Frontiers in Stem Cells & Cancer
- Place of Presentation
  Heidelberg, Germany
- Year and Date
  2015-03-29 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-25870384

1. 笹沼博之 (00531691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 中嶋洋行 (10467657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 長谷川洋介 (30396783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山本拓也 (60546993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 迫圭輔 (50786291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUMOTO Yoshiaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. TOI Masakazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. SATO Fumikai

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Itou Junji 伊東 潤二

ITOU Junji 伊東 潤二

Research Projects

Research Products

Co-Researchers

生体内でのNAD+量低下による初期乳がん増殖開始のメカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analses of the formation of oxygen exchange niche through endothelial-epithelial interaction

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

妊娠経験の乳がん予防効果のメカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of novel mouse early breast cancer induction model for studies of breast tumorigenesis and preventionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Classification and characterization of a novel basal-like breast cancer group.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Supplementation with Fermented Barley Extract Prevents Mammary Epithelial Cell Invasion in an Early Breast Cancer Model2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Eribulin mesylate-induced c-Fos upregulation enhances cell survival in breast cancer cell lines2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Estrogen Induces Mammary Ductal Dysplasia via the Upregulation of Myc Expression in a DNA-Repair-Deficient Condition2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] An optical labeling-based proliferation assay system reveals the paracrine effect of interleukin-6 in breast cancer.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Function of the Developmental Transcription Factor SALL4 in Cancer2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sal-like 4 (SALL4) suppresses CDH1 expression and maintains cell dispersion in basal-like breast cancer2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] 新規の乳癌誘導系による発癌メカニズムおよび超初期乳癌の研究2020

Author(s)

Organizer

Data Source

[Presentation] Tumor promoting effect of macrophages in a mouse early breast cancer model2020

Author(s)

Organizer

Data Source

Itou Junji 伊東潤二

ITOU Junji 伊東潤二