Saika Fumihiro 雑賀史浩

Researcher Number	10644099
Other IDs
Affiliation (Current)	2025: 宝塚医療大学, 和歌山保健医療学部, 准教授 2025: 和歌山県立医科大学, 薬学部, 客員研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 和歌山県立医科大学, 薬学部, 客員研究員 2014 – 2023: 和歌山県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Applied pharmacology / Basic Section 47040:Pharmacology-related Except Principal Investigator Basic Section 48010:Anatomy-related / Basic Section 55050:Anesthesiology-related / Pain science / Anesthesiology
Keywords	Principal Investigator ミクログリア / ドパミン / メタンフェタミン / 前頭前皮質 / ケモカイン / 薬物依存 / 薬理学 / サイトカイン / ガストリン放出ペプチド受容体 / CNO … More / Gi-DREADD / ガストリン放出ペプチド（GRP) / イミキモド / 痒み / DREADD / ガストリン放出ペプチド / 脊髄 / かゆみ / 乾癬 / 行動実験 / CPP試験 / 再発 / ドパミンアゴニスト / 脳内炎症 / 再燃・再発 / CPPテスト / CPP / コカイン / 炎症 / 腹側被蓋野 / 神経炎症 / 脳・神経 / 依存 / ドパミン受容体 / ventral tegmental area / prefrontal cortex / dopamine receptor / place preference / chemokine / methamphetamine … More Except Principal Investigator ミクログリア / 神経障害性疼痛 / 脊髄 / アロディニア / 神経炎症 / ケモカイン / ニコチン受容体 / サイトカイン / マクロファージ / 神経変性疾患 / 細胞死 / Tau蛋白質 / 糖尿病 / SUMO化修飾 / 認知症 / 小胞体ストレス / Tau / SUMO2 / SUMO1 / 接触皮膚炎 / 乾癬 / DREADD / 皮膚炎 / 痒み / 痛み / ニューロペプチド / 中枢感作 / 2型糖尿病 / 末梢感作 / 脊髄後角 / 坐骨神経 / 炎症 / ニコチン / ニコチン性アセチルコリン受容体 / STAT3 / α4β2 / フェノタイプ / 慢性炎症 Less

糖尿病における小胞体ストレス応答とSUMO化
- Principal Investigator
  
  松崎伸介
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Morinomiya University of Medical Sciences
Elucidation of the molecular basis of intractable itch associated with psoriasisPrincipal Investigator
- Principal Investigator
  
  Saika Fumihiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Wakayama Medical University
Molecular mechanisms of nociceptive somatosensory disorders revealed by a novel regulatory method of microglia
- Principal Investigator
  
  Kiguchi Norikazu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Wakayama Medical University
Elucidation of drug dependence formation / relapse molecular mechanism focusing on neuroinflammationPrincipal Investigator
- Principal Investigator
  
  Saika Fumihiro
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Wakayama Medical University
Pathogenesis of neuropathic pain due to interaction between peripheral and central sensitization
- Principal Investigator
  
  Kiguchi Norikazu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Wakayama Medical University
Novel therapeutics for macrophage-driven inflammatory diseases via nicotinic acetylcholine receptor signaling
- Principal Investigator
  
  Kishioka Shiroh
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Wakayama Medical University
Elucidation of novel drug dependent control mechanism focused on cytokine-chemokine networkPrincipal Investigator
- Principal Investigator
  
  Saika Fumihiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Wakayama Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Characterization of spinal microglial activation in a mouse model of imiquimod-induced psoriasis2023
- Author(s)
  Saika Fumihiro、Fukazawa Yohji、Kishioka Shiroh、Kiguchi Norikazu
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 153 Issue: 4 Pages: 183-187
- DOI
  10.1016/j.jphs.2023.09.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07088
[Journal Article] Tas2R signaling enhances mouse neutrophil migration via a ROCK-dependent pathway2022
- Author(s)
  Kobayashi Daichi、Watarai Tomoya、Ozawa Madoka、Kanda Yasuhiro、Saika Fumihiro、Kiguchi Norikazu、Takeuchi Arata、Ikawa Masahito、Matsuzaki Shinsuke、Katakai Tomoya
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 973880-973880
- DOI
  10.3389/fimmu.2022.973880
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07088, KAKENHI-PROJECT-21K06759, KAKENHI-PROJECT-22K06998, KAKENHI-PROJECT-22K17823, KAKENHI-PROJECT-17KK0197, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19K07603, KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-20K09227, KAKENHI-PROJECT-19K22528, KAKENHI-PROJECT-19K16697, KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-21H02653
[Journal Article] Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice2021
- Author(s)
  Saika Fumihiro、Matsuzaki Shinsuke、Kishioka Shiroh、Kiguchi Norikazu
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 4 Pages: 874-874
- DOI
  10.3390/cells10040874
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-20K07088, KAKENHI-PROJECT-20K09227
[Journal Article] Chemogenetic activation of central gastrin-releasing peptide-expressing neurons elicits itch-related scratching behavior in male and female mice Pharmacology Research and Perspective2021
- Author(s)
  Norikazu Kiguchi, Yohji Fukazawa, Ayano Saika, Daisuke Uta, Fumihiro Saika, Tomoe Y. Nakamura, Mei-Chuan Ko, Shiroh Kishioka
- Journal Title
  
  Pharmacology Research and Perspective
  
  Volume: - Issue: 3 Pages: 1-11
- DOI
  10.1002/prp2.790
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06867, KAKENHI-PROJECT-19K07111, KAKENHI-PROJECT-19K09323, KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-20K07088, KAKENHI-PROJECT-20K09227
[Journal Article] Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain2020
- Author(s)
  Fumihiro Saika, Shinsuke Matsuzaki, Daichi Kobayashi, Yuya Ideguchi, Tomoe Y Nakamura, Shiroh Kishioka, Norikazu Kiguchi
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 11 Pages: 925-925
- DOI
  10.3389/fphar.2020.00925
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06867, KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-20K07088, KAKENHI-PROJECT-20K09227, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-19K16697
[Journal Article] GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn2020
- Author(s)
  Kiguchi Norikazu、Uta Daisuke、Ding Huiping、Uchida Hitoshi、Saika Fumihiro、Matsuzaki Shinsuke、Fukazawa Yohji、Abe Manabu、Sakimura Kenji、Ko Mei-Chuan、Kishioka Shiroh
- Journal Title
  
  Neuropharmacology
  
  Volume: 170 Pages: 108025-108025
- DOI
  10.1016/j.neuropharm.2020.108025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07111, KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19K09323, KAKENHI-PROJECT-20K07088
[Journal Article] Insufficient efferocytosis by M2-like macrophages as a possible mechanism of neuropathic pain induced by nerve injury.2020
- Author(s)
  Kobayashi D, Kiguchi N, Saika F, Kishioka S, Matsuzaki S.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: Epub Issue: 1 Pages: 216-223
- DOI
  10.1016/j.bbrc.2020.02.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-19K16697
[Journal Article] Critical role of GRP receptor?expressing neurons in the spinal transmission of imiquimod‐induced psoriatic itch2020
- Author(s)
  Kiguchi Norikazu、Saika Fumihiro、Fukazawa Yohji、Matsuzaki Shinsuke、Kishioka Shiroh
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: 40 Issue: 3 Pages: 287-290
- DOI
  10.1002/npr2.12120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07111, KAKENHI-PROJECT-20K07088, KAKENHI-PROJECT-20K09227
[Journal Article] Inflammatory Macrophages in the Sciatic Nerves Facilitate Neuropathic Pain Associated with Type 2 Diabetes Mellitus.2019
- Author(s)
  Saika F, Kiguchi N, Matsuzaki S, Kobayashi D, Kishioka S.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 368(3) Issue: 3 Pages: 535-544
- DOI
  10.1124/jpet.118.252668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-16K08994
[Journal Article] CXCL1 is responsible for cocaine-induced reward in mice.2018
- Author(s)
  Saika F, Matsuzaki S, Kobayashi D, Kiguchi N, Kishioka S.
- Journal Title
  
  Neuropsychopharmacol Rep
  
  Volume: 38(3) Pages: 145-148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15758
[Journal Article] Upregulation of CCL7 and CCL2 in reward system mediated through dopamine D1 receptor signaling underlies methamphetamine-induced place preference in mice.2018
- Author(s)
  Saika F, Kiguchi N, Wakida N, Kobayashi D, Fukazawa Y, Matsuzaki S, Kishioka S.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 665 Pages: 33-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15758
[Journal Article] Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury2018
- Author(s)
  Kiguchi N, Kobayashi D, Saika F, Matsuzaki S, Kishioka S
- Journal Title
  
  J Neuroinflammation
  
  Volume: 15 Issue: 1 Pages: 96-96
- DOI
  10.1186/s12974-018-1133-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08994, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-15K10563
[Journal Article] Pharmacological Regulation of Neuropathic Pain Driven by Inflammatory Macrophages2017
- Author(s)
  Kiguchi N, Kobayashi D, Saika F, Matsuzaki S, Kishioka S
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 11 Pages: 2296-2296
- DOI
  10.3390/ijms18112296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08994, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-15K10563
[Journal Article] Peripheral administration of interleukin-13 reverses inflammatory macrophage and tactile allodynia in mice with partial sciatic nerve ligation2017
- Author(s)
  Kiguchi Ｎ, Sakaguchi H, Kadowaki Y, Saika F, Fukazawa Y, Matsuzaki S, Kishioka S
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 133 Issue: 1 Pages: 53-56
- DOI
  10.1016/j.jphs.2016.11.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10563, KAKENHI-PROJECT-16K08994
[Journal Article] Peripheral interleukin-4 ameliorates inflammatory macrophage-dependent neuropathic pain.2015
- Author(s)
  Kiguchi N, Kobayashi Y, Saika F, Sakaguchi H, Maeda T, Kishioka S
- Journal Title
  
  Pain
  
  Volume: 156(4) Issue: 4 Pages: 684-93
- DOI
  10.1097/j.pain.0000000000000097
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24590734, KAKENHI-PROJECT-24592356, KAKENHI-PROJECT-25460108, KAKENHI-PROJECT-25861397, KAKENHI-PROJECT-26860357
[Journal Article] Peripheral alpha4beta2 nicotinic acetylcholine receptor signalling attenuates tactile allodynia and thermal hyperalgesia after nerve injury in mice.2015
- Author(s)
  Saika F, Kiguchi N, Kobayashi Y, Kishioka S
- Journal Title
  
  Acta Physiol (Oxf)
  
  Volume: 213(2) Issue: 2 Pages: 462-71
- DOI
  10.1111/apha.12437
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356, KAKENHI-PROJECT-25861397, KAKENHI-PROJECT-26860357
[Journal Article] The role of CC-chemokine ligand 2 in the development of psychic dependence on methamphetamine2015
- Author(s)
  Saika F, Kiguchi N, Kishioka S.
- Journal Title
  
  Nihon Arukoru Yakubutsu Igakkai Zasshi
  
  Volume: 50(5) Pages: 189-95
- NAID
  40022403175
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860357
[Journal Article] Epigenetic regulation of CC-chemokine ligand 2 in nonresolving inflammation.2014
- Author(s)
  Kiguchi N, Saika F, Kobayashi Y, Kishioka S
- Journal Title
  
  Biomol Concepts
  
  Volume: 5(4) Issue: 4 Pages: 265-73
- DOI
  10.1515/bmc-2014-0022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356, KAKENHI-PROJECT-25861397, KAKENHI-PROJECT-26860357
[Presentation] マクロファージ・ミクログリアの性差と神経障害性疼痛形成機構2024
- Author(s)
  雑賀史浩、木口倫一
- Organizer
  第144回日本薬理学会　近畿部会
- Data Source
  KAKENHI-PROJECT-20K07088
[Presentation] Andorogens determine sex differences of spinal microglia2022
- Author(s)
  木口倫一、雑賀史浩、波多野裕、日野信次朗、鈴木堅太郎
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07088
[Presentation] 脊髄ミクログリアの性差はアンドロゲンによって決定される2022
- Author(s)
  木口倫一, 雑賀史浩, 波多野裕, 日野信次朗, 鈴木堅太郎
- Organizer
  第96回日本薬理学会年会・第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09227
[Presentation] 脊髄ミクログリアの性差形成におけるアンドロゲンシグナルの関与2022
- Author(s)
  木口倫一, 雑賀史浩, 波多野裕, 日野信次朗, 鈴木堅太郎
- Organizer
  第142回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K09227
[Presentation] 脊髄ミクログリアの性差に及ぼすアンドロゲンの影響2022
- Author(s)
  木口倫一, 波多野裕, 雑賀史浩, 日野信次朗, 鈴木堅太郎
- Organizer
  第141回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K09227
[Presentation] 脊髄ミクログリアの性差に及ぼすアンドロゲンの影響2022
- Author(s)
  木口倫一、波多野裕、雑賀史浩、日野信次朗、鈴木堅太郎
- Organizer
  第141回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K07088
[Presentation] 脊髄ミクログリアによる性依存的なアロディニア誘発作用2021
- Author(s)
  木口倫一、雑賀史浩
- Organizer
  第43回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-20K07088
[Presentation] Gi/Gq DREADDを用いた脊髄ミクログリアの操作による性依存的な疼痛制御機構2021
- Author(s)
  雑賀史浩, 木口倫一, 松﨑伸介, 西谷友重
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K09227
[Presentation] 脊髄ミクログリアによる性依存的なアロディニア誘発作用2021
- Author(s)
  木口倫一、雑賀史浩
- Organizer
  第43回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-20K09227
[Presentation] 苦味物質は ROCK シグナリングを増強させ好中球遊走を促進する2021
- Author(s)
  小林大地、渡井友也、小澤まどか、神田泰洋、雑賀史浩、木口倫一、松崎伸介、片貝智哉
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07088
[Presentation] Sex-dependent pain-regulatory effects of spinal microglia using Gi / Gq DREADD systems in mice2021
- Author(s)
  雑賀史浩、木口倫一、松崎伸介、西谷-中村友重
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07088
[Presentation] DREADDシステムを用いたマクロファージ／ミクログリア機能制御が神経障害性疼痛モデルに及ぼす疼痛抑制効果2020
- Author(s)
  雑賀史浩、木口倫一、小林大地、出口雄也、松﨑伸介、岸岡史郎
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] DREADDによるマクロファージ／ミクログリアの抑制は雄性マウスの神経障害性疼痛モデルにおいて抗アロディニア効果を示す2020
- Author(s)
  出口雄也、雑賀史浩、木口倫一、小林大地、松﨑伸介、岸岡史郎
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] 乾癬モデルマウスの痒みを担う脊髄内調節機構2019
- Author(s)
  木口倫一、雑賀史浩、松﨑伸介、岸岡史郎
- Organizer
  136回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] 神経障害性疼痛モデルマウスにおけるDREADDシステムを用いたマクロファージ／ミクログリア活性操作2019
- Author(s)
  雑賀史浩、木口倫一、小林大地、松﨑伸介
- Organizer
  疼痛学会
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] 神経障害性疼痛に関与するマクロファージ／ミクログリアの機能解析.2018
- Author(s)
  雑賀史浩, 木口倫一, 小林大地, 松﨑伸介, 岸岡史郎.
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 神経障害性疼痛に関与するマクロファージ/ミクログリアの機能解析2018
- Author(s)
  雑賀史浩、木口倫一、小林大地、松崎伸介、岸岡史郎
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] Inflammatory macrophages mediate neuropathic pain caused by type 2 diabetes mellitus.2018
- Author(s)
  Kiguchi N, Saika F, Kobayashi D, Matsuzaki S, Kishioka S.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 炎症性マクロファージは神経傷害後のミクログリア活性化および機械的アロディニアを調節する2018
- Author(s)
  木口倫一、雑賀史浩、小林大地、松崎伸介、岸岡史郎
- Organizer
  第４０回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] Curcumin attenuates methamphetamine-induced conditioned place preference via inhibition of CC chemokine ligand 2 expression2018
- Author(s)
  F. Saika, N. Kiguchi, D. Kobayashi, S. Matsuzaki , S. Kishioka
- Organizer
  31th ECNP Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] 神経障害性疼痛モデルマウスを用いた抗炎症性マクロファージの機能解析.2018
- Author(s)
  小林大地, 木口倫一, 雑賀史浩, 松﨑伸介, 岸岡史郎.
- Organizer
  第38回鎮痛薬・オピオイドペプチドシンポジウム
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] Possible involvement of chemokine ligands in addictive drugs-induced conditioned place preference in mice2018
- Author(s)
  S. Kishioka, F. Saika, N. Kiguchi, D. Kobayashi, S. Matsuzaki
- Organizer
  31th ECNP Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] Inflammatory macrophages in the injured peripheral nerves facilitate spinal microglial activation and neuropathic pain in mice.2018
- Author(s)
  Kiguchi N, Saika F, Kobayashi D, Matsuzaki S, Kishioka S.
- Organizer
  17th World Congress on Pain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] α4β2 ニコチン性アセチルコリン受容体アゴニストはマウスにおける2型糖尿病性神経障害性疼痛を減弱する.2018
- Author(s)
  雑賀史浩, 木口倫一, 小林大地, 松﨑伸介, 岸岡史郎.
- Organizer
  第40回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] Inflammatory macrophages in the injured peripheral nerves facilitate spinal microglial activation and neuropathic pain in mice2018
- Author(s)
  N. Kiguchi, F. Saika, D. Kobayashi, S. Matsuzaki , S. Kishioka
- Organizer
  17th IASP World Congress of Pain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] α4β2ニコチン性アセチルコリン受容体アゴニストはマウスにおける2型糖尿病性神経障害性疼痛を減弱する2018
- Author(s)
  F. Saika, N. Kiguchi, D. Kobayashi, S. Matsuzaki , S. Kishioka
- Organizer
  第４０回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] Inflammatory macrophages mediate neuropathic pain caused by type 2 diabetes mellitus2018
- Author(s)
  N. Kiguchi, F. Saika, D. Kobayashi, S. Matsuzaki , S. Kishioka
- Organizer
  第18回国際薬理学・臨床薬理学会議（WCP2018）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] 炎症性マクロファージは神経傷害後のミクログリア活性化および機械的アロディニアを調節する.2018
- Author(s)
  木口倫一, 雑賀史浩, 小林大地, 松﨑伸介, 岸岡史郎.
- Organizer
  第40回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 傷害神経に浸潤するマクロファージは脊髄ミクログリアの活性化を調節する2017
- Author(s)
  木口倫一、雑賀史浩、小林大地、松﨑伸介、岸岡史郎
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-15K10563
[Presentation] Regulation of COPI vesicle transport via Scyl1 methylation under ER-stress2017
- Author(s)
  S. Matsuzaki, G. Amano, Y.Mori, D. kobayashi, H. Takamura, K. Miyoshi, T. Yoshimura, F. Saika, N. Kiguchi, T. Katayama, S. Kishioka
- Organizer
  ASCB2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] 傷害神経に浸潤するマクロファージは脊髄ミクログリアの活性化を調節する2017
- Author(s)
  木口倫一、雑賀史浩、小林大地、松﨑伸介、岸岡史郎
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 2型糖尿病発症カニクイザルの脊髄後角におけるケモカイン発現変動2017
- Author(s)
  木口倫一、Huiping Ding、雑賀史浩、松﨑伸介、岸岡史郎、Mei-Chuan Ko
- Organizer
  生理学研究所研究会「痛みの理解を目指した先端的アプローチ」
- Place of Presentation
  岡崎
- Year and Date
  2017-01-31
- Data Source
  KAKENHI-PROJECT-15K10563
[Presentation] Peripheral pro-inflammation cytokines participate in chronic morphine-induced hyperalgesia in mice.2017
- Author(s)
  S. Kishioka, F. Saika, N. Kiguchi, S. Matsuzaki
- Organizer
  CPDD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] モルヒネ禁断時の血清コルチコステロン上昇におけるα4β2ニコチン性アセチルコリン受容体の関与2017
- Author(s)
  岸岡史郎、山本千鶴子、小林大地、雑賀史浩、木口倫一、松崎伸介
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] 神経傷害後の末梢マクロファージによる脊髄ミクログリア調節作用2017
- Author(s)
  木口倫一、小林大地、雑賀史浩、松﨑伸介、岸岡史郎
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15K10563
[Presentation] 食餌性肥満に及ぼす脱酸梅果汁の抑制効果2017
- Author(s)
  木口倫一、雑賀史浩、小林大地、松崎伸介、岸岡史郎
- Organizer
  第15回果実酒・果実飲料と健康に関する研究
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] 2型糖尿病発症カニクイザルの脊髄後角におけるケモカイン発現変動2017
- Author(s)
  木口倫一、Huiping Ding、雑賀史浩、松﨑伸介、岸岡史郎、Mei-Chuan Ko
- Organizer
  生理学研究所研究会「痛みの理解を目指した先端的アプローチ」
- Place of Presentation
  岡崎
- Year and Date
  2017-01-31
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] マクロファージ上で発現するα4β2ニコチン性アセチルコリン受容体活性化による神経障害性疼痛の緩和2017
- Author(s)
  雑賀史浩、木口倫一、松﨑伸介、岸岡史郎
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15K10563
[Presentation] ニコチン性アセチルコリン受容体リガンドの末梢投与は神経障害性疼痛を改善する2017
- Author(s)
  木口倫一、雑賀史浩、松﨑伸介、岸岡史郎
- Organizer
  第5回ニューロカンファレンス和歌山
- Place of Presentation
  和歌山
- Year and Date
  2017-01-07
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 神経傷害後の末梢マクロファージによる脊髄ミクログリア調節作用2017
- Author(s)
  木口倫一、小林大地、雑賀史浩、松﨑伸介、岸岡史郎
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 神経傷害後の末梢マクロファージによる脊髄ミクログリア調節作用2017
- Author(s)
  木口倫一、小林大地、雑賀史浩、松崎伸介、岸岡史郎
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] マクロファージ上で発現するα4β2ニコチン性アセチルコリン受容体活性化による神経障害性疼痛の緩和2017
- Author(s)
  雑賀史浩、木口倫一、松﨑伸介、岸岡史郎
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 傷害神経に浸潤するマクロファージは脊髄ミクログリアの活性化を調節する2017
- Author(s)
  木口倫一、雑賀史浩、小林大地、松崎伸介、岸岡史郎
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] ニコチン性アセチルコリン受容体リガンドの末梢投与は神経障害性疼痛を改善する2017
- Author(s)
  木口倫一、雑賀史浩、松﨑伸介、岸岡史郎
- Organizer
  第5回ニューロカンファレンス和歌山
- Place of Presentation
  和歌山
- Year and Date
  2017-01-07
- Data Source
  KAKENHI-PROJECT-15K10563
[Presentation] クルクミンによるメタンフェタミン誘発精神的依存形成の抑制2017
- Author(s)
  雑賀史浩、木口倫一、小林大地、松崎伸介、岸岡史郎
- Organizer
  第15回果実酒・果実飲料と健康に関する研究
- Data Source
  KAKENHI-PROJECT-17K15758
[Presentation] CC-chemokines facilitate methamphetamine dependence through the activation of dopamine system in mice2016
- Author(s)
  木口倫一、雑賀史浩、松崎伸介、岸岡史郎
- Organizer
  17th Pacific Rim College of Psychiatrists scientific Meeting
- Place of Presentation
  Kaohsiung, Taiwan
- Year and Date
  2016-11-03
- Invited
- Data Source
  KAKENHI-PROJECT-26860357
[Presentation] クルクミンはCCL2発現抑制を介してメタンフェタミン精神的依存を減弱させる2016
- Author(s)
  雑賀史浩、木口倫一、松崎伸介、岸岡史郎
- Organizer
  第51回日本アルコール・アディクション医学会総会
- Place of Presentation
  東京
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26860357
[Presentation] メタンフェタミン精神依存形成における中脳辺縁系炎症性ケモカインの関与2016
- Author(s)
  雑賀史浩、木口倫一、松崎伸介、岸岡史郎
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  ソウル、韓国
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26860357
[Presentation] Participation of CC-Chemokine Ligands (CCL2 and CCL7) in reward system on methamphetamine-induced psychological dependence in mice.2016
- Author(s)
  岸岡史郎、雑賀史浩、松崎伸介、M.-C. Ko、木口倫一、
- Organizer
  78th Annual Meeting - College on Problems of drug Dependence
- Place of Presentation
  La Quinta Resort and Club, Palm Springs, California, USA
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-26860357
[Presentation] ドパミンD1受容体を介したCC-ケモカイン発現増加はメタンフェタミン精神的依存形成に関与する2015
- Author(s)
  雑賀史浩、木口倫一、松崎伸介、岸岡史郎
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  岐阜
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-26860357
[Presentation] CC-ケモカインはメタンフェタミン精神的依存形成に関与する2014
- Author(s)
  雑賀史浩、木口倫一、小林悠佳、岸岡史郎
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-26860357
[Presentation] 炎症性ケモカインによるメタンフェタミン依存調節機構2014
- Author(s)
  木口倫一、雑賀史浩、小林悠佳、岸岡史郎
- Organizer
  平成26年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  神奈川
- Year and Date
  2014-10-03
- Data Source
  KAKENHI-PROJECT-26860357
[Presentation] メタンフェタミン精神的依存における CC- ケモカインの役割2014
- Author(s)
  雑賀史浩、木口倫一、小林悠佳、岸岡史郎
- Organizer
  平成26年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  神奈川
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-26860357

1. KIGUCHI Norikazu (90433341)

# of Collaborated Projects: 4 results

# of Collaborated Products: 39 results
2. Kishioka Shiroh (60137255)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
3. 松崎伸介 (60403193)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. KOBAYASHI Daichi

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
5. 深澤洋滋 (70336882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 歌大介 (70598416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 田熊一敞 (90289025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 高村明孝 (80514398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 長井克仁 (00351271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Wakida Naoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Imai Kazuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MATSUZAKI Shinsuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
13. KOBAYASHI Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 西谷友重

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Saika Fumihiro 雑賀 史浩

Research Projects

Research Products

Co-Researchers

糖尿病における小胞体ストレス応答とSUMO化

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Elucidation of the molecular basis of intractable itch associated with psoriasisPrincipal Investigator

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Molecular mechanisms of nociceptive somatosensory disorders revealed by a novel regulatory method of microglia

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Elucidation of drug dependence formation / relapse molecular mechanism focusing on neuroinflammationPrincipal Investigator

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Pathogenesis of neuropathic pain due to interaction between peripheral and central sensitization

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Novel therapeutics for macrophage-driven inflammatory diseases via nicotinic acetylcholine receptor signaling

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Elucidation of novel drug dependent control mechanism focused on cytokine-chemokine networkPrincipal Investigator

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[Journal Article] Characterization of spinal microglial activation in a mouse model of imiquimod-induced psoriasis2023

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[Journal Article] Tas2R signaling enhances mouse neutrophil migration via a ROCK-dependent pathway2022

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[Journal Article] Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice2021

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[Journal Article] Chemogenetic activation of central gastrin-releasing peptide-expressing neurons elicits itch-related scratching behavior in male and female mice Pharmacology Research and Perspective2021

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[Journal Article] Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain2020

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[Journal Article] GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn2020

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[Journal Article] Insufficient efferocytosis by M2-like macrophages as a possible mechanism of neuropathic pain induced by nerve injury.2020

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Saika Fumihiro 雑賀史浩