Akamatsu Hiroaki 赤松弘朗

Researcher Number	10646582
Other IDs	https://orcid.org/0000-0001-5856-5512
Affiliation (Current)	2025: 和歌山県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 和歌山県立医科大学, 医学部, 准教授 2017 – 2020: 和歌山県立医科大学, 医学部, 講師 2014 – 2017: 和歌山県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Respiratory organ internal medicine / Tumor diagnostics Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 58060:Clinical nursing-related / Respiratory organ internal medicine
Keywords	Principal Investigator EGFR遺伝子変異 / リキッドバイオプシー / Liquid biopsy / 肺癌 / 非小細胞肺がん / 免疫チェックポイント阻害剤 / heterogeneity / 分子標的治療薬 / 非小細胞肺癌 / 臨床呼吸器学 … More / cell free DNA / 血中循環腫瘍細胞 / lung cancer / immunotherapy / Liquid Biopsyに関する研究 / liquid biopsy / 肺がん … More Except Principal Investigator 分子標的治療 / 小細胞肺癌 / RNA / 機械学習 / 小細胞がん / バイオマーカー / がん患者 / アドヒアランス / QOL / アピアランス / セルフケア / 皮膚障害 / 肺癌 / 新規診断技術 / EGFR / デジタルPCR / EGFR変異 / リキッドバイオプシー / 肺がん / がん個別化医療 Less

マルチオミクス解析による免疫チェックポイント阻害剤低感受性肺癌の効果予測因子同定Principal Investigator
- Principal Investigator
  
  赤松弘朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Wakayama Medical University
小細胞肺癌における網羅的RNA解析と機械学習による免疫療法奏功予測パネルの開発
- Principal Investigator
  
  藤本大智
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Wakayama Medical University
分子標的治療を受ける進行肺がん患者の皮膚障害セルフケア困難の実態解明
- Principal Investigator
  
  山口昌子
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Wakayama Medical University
Impact of tumor heterogeneity of driver mutation-positive lung cancerPrincipal Investigator
- Principal Investigator
  
  Hiroaki Akamtsu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Wakayama Medical University
Exploratory biomarker analysis to predict the efficacy of immune checkpoint inhibitors using cell-free DNAPrincipal Investigator
- Principal Investigator
  
  Akamatsu Hiroaki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Wakayama Medical University
Multiplex mutation detection using digital PCR method and its clinical utility
- Principal Investigator
  
  Yamamoto Nobuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Wakayama Medical University
Exploratory analyses of comprehensive and quantitative mutation profiling using cell-free DNAPrincipal Investigator
- Principal Investigator
  
  Akamatsu Hiroaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Wakayama Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book Patent

[Book] オンコロジークリニカルガイド肺癌化学療法2019
- Author(s)
  赤松弘朗
- Total Pages
  375
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18K07271
[Book] Medical Practice, 分子標的薬と血管新生阻害剤2019
- Author(s)
  赤松弘朗
- Total Pages
  160
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-18K07271
[Book] 呼吸器疾患最新の治療2019-20202019
- Author(s)
  杉本武哉, 赤松弘朗, 山本信之
- Total Pages
  534
- Publisher
  南江堂
- ISBN
  9784524245574
- Data Source
  KAKENHI-PROJECT-18K07271
[Book] 肺癌診療ガイドライン 2018年版　第5版2018
- Author(s)
  赤松弘朗、山本信之、他
- Total Pages
  420
- Publisher
  金原出版
- ISBN
  9784307203913
- Data Source
  KAKENHI-PROJECT-18K07271
[Book] がん免疫療法ガイドライン　第2版2018
- Author(s)
  赤松弘朗、山本信之、他
- Total Pages
  162
- Publisher
  金原出版
- ISBN
  9784307101950
- Data Source
  KAKENHI-PROJECT-18K07271
[Book] どのような肺がん患者に化学療法が行われるか2016
- Author(s)
  赤松弘朗, 山本信之
- Total Pages
  6
- Publisher
  学研
- Data Source
  KAKENHI-PROJECT-15K09226
[Book] 抗癌薬の副作用対策2016
- Author(s)
  赤松弘朗, 山本信之
- Total Pages
  2
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-15K09226
[Book] 分子標的時代における治療推奨の重みづけをどうするか？2016
- Author(s)
  赤松弘朗, 山本信之
- Total Pages
  5
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K09226
[Book] デジタルPCRの原理と臨床腫瘍学での有用性2016
- Author(s)
  赤松弘朗, 洪泰浩, 山本信之
- Total Pages
  5
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K09226
[Book] 各種がんにおける化学療法 1肺癌2016
- Author(s)
  赤松弘朗, 山本信之
- Total Pages
  6
- Publisher
  学研
- Data Source
  KAKENHI-PROJECT-15K09226
[Book] EBMの手法による肺癌診療ガイドライン2014年版2014
- Author(s)
  赤松弘朗, 山本信之
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-26870509
[Book] 現在進行中の大規模無作為化比較試験2014
- Author(s)
  赤松弘朗, 山本信之
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-26870509
[Book] 腫瘍病理鑑別診断アトラス肺癌2014
- Author(s)
  赤松弘朗, 山本信之
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-26870509
[Book] がん薬物療法の作用機序　殺細胞性抗悪性腫瘍薬　白金製剤･アルキル化薬･抗がん性抗生物質2014
- Author(s)
  赤松弘朗, 山本信之
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26870509
[Book] 呼吸器疾患診療最新ガイドライン2014
- Author(s)
  菊池崇史, 赤松弘朗, 山本信之
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-26870509
[Book] Ⅲ期非小細胞肺癌の化学放射線療法.2014
- Author(s)
  赤松弘朗, 山本信之
- Publisher
  へるす出版
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer2024
- Author(s)
  Lin Chang-Ching, Hiroaki Akamatsu, et al.
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1
- DOI
  10.1038/s41467-024-46495-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07175
[Journal Article] Mannitol versus furosemide in patients with thoracic malignancies who received cisplatin‐based chemotherapy using short hydration: A randomized phase <scp>II</scp> trial2024
- Author(s)
  Murakami Eriko、Akamatsu Hiroaki、Teraoka Shunsuke、Takakura Toshiaki、Takase Eri、Tanaka Masanori、Kaki Takahiro、Harutani Yuhei、Furuta Katsuyuki、Sugimoto Takeya、Shibaki Ryota、Fujimoto Daichi、Hayata Atsushi、Ozawa Yuichi、Nakanishi Masanori、Koh Yasuhiro、Shimokawa Toshio、Yamamoto Nobuyuki
- Journal Title
  
  Cancer Medicine
  
  Volume: 13 Issue: 4
- DOI
  10.1002/cam4.6839
- Data Source
  KAKENHI-PROJECT-22K07175
[Journal Article] Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer2024
- Author(s)
  Shibaki Ryota、Fujimoto Daichi、Nozawa Tsukasa、Sano Akira、Kitamura Yuka、Fukuoka Junya、Sato Yuki、Kijima Takashi、Matsumoto Hirotaka、Yokoyama Toshihide、Miura Satoru、Hata Akito、Tamiya Motohiro、Taniguchi Yoshihiko、Sugisaka Jun、Furuya Naoki、Tanaka Hisashi、Yamamoto Nobuyuki、Koh Yasuhiro、Akamatsu Hiroaki
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 12 Issue: 2 Pages: e007987-e007987
- DOI
  10.1136/jitc-2023-007987
- Data Source
  KAKENHI-PROJECT-22K07175
[Journal Article] Outcomes of Chemoimmunotherapy Among Patients With Extensive-Stage Small Cell Lung Cancer According to Potential Clinical Trial Eligibility2023
- Author(s)
  Fujimoto Daichi, Akamatsu Hiroaki, et al.
- Journal Title
  
  JAMA Network Open
  
  Volume: 6 Issue: 2 Pages: e230698-e230698
- DOI
  10.1001/jamanetworkopen.2023.0698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07175
[Journal Article] Effectiveness and Safety of Atezolizumab Monotherapy in Previously Treated Japanese Patients With Unresectable Advanced or Recurrent NSCLC: A Multicenter, Prospective, Observational Study (J-TAIL)2023
- Author(s)
  Miura Satoru, Nishio Makoto, Akamatsu Hiroaki, et al.
- Journal Title
  
  JTO Clinical and Research Reports
  
  Volume: 4 Issue: 3 Pages: 100484-100484
- DOI
  10.1016/j.jtocrr.2023.100484
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07175
[Journal Article] Randomized, open-label phase II study of brigatinib and carboplatin plus pemetrexed and brigatinib alone for chemotherapy-naive patients with ALK-rearranged non-squamous non-small cell lung cancer: Treatment Rationale and Protocol Design of the B-DASH Study (WJOG 14720 L)2023
- Author(s)
  Wakuda Kazushige、Kenmotsu Hirotsugu、Sato Yuki、Nakamura Atsushi、Akamatsu Hiroaki、Tachihara Motoko、Miura Satoru、Yokoyama Toshihide、Mori Keita、Nakagawa Kazuhiko、Yamamoto Nobuyuki
- Journal Title
  
  BMC Cancer
  
  Volume: NA
- DOI
  10.21203/rs.3.rs-2550375/v1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07175
[Journal Article] Carboplatin and irinotecan (CI) vs. carboplatin and etoposide (CE) for the treatment of extended-stage small-cell lung cancer in an elderly population: A phase II/III randomized control trial2023
- Author(s)
  Shimokawa Tsuneo、Okamoto Hiroaki、Machida Ryunosuke、Misumi Yuki、Hosomi Yukio、Yoneshima Yasuto、Tanaka Hiroshi、Okishio Kyoichi、Simizu Junichi、Goto Koichi、Akamatsu Hiroaki、Kubota Kaoru、Nakagawa Kazuhiko、Horinouchi Hidehito、Ando Masahiko、Kataoka Tomoko、Ohe Yuichiro
- Journal Title
  
  Lung Cancer
  
  Volume: 181 Pages: 107195-107195
- DOI
  10.1016/j.lungcan.2023.107195
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07175, KAKENHI-PROJECT-18K07443
[Journal Article] Biomarker Testing in Patients With Unresectable Advanced or Recurrent Non?Small Cell Lung Cancer2023
- Author(s)
  Sakamoto Tomohiro, Hiroaki Akamatsu, et al.
- Journal Title
  
  JAMA Network Open
  
  Volume: 6 Issue: 12 Pages: e2347700-e2347700
- DOI
  10.1001/jamanetworkopen.2023.47700
- Data Source
  KAKENHI-PROJECT-22K07175
[Journal Article] Nivolumab Retreatment in Non?Small Cell Lung Cancer Patients Who Responded to Prior Immune Checkpoint Inhibitors and Had ICI-Free Intervals (WJOG9616L)2022
- Author(s)
  Akamatsu Hiroaki、Teraoka Shunsuke、Takamori Shinkichi、Miura Satoru、Hayashi Hidetoshi、Hata Akito、Toi Yukihiro、Shiraishi Yoshimasa、Mamesaya Nobuaki、Sato Yuki、Furuya Naoki、Oyanagi Jun、Koh Yasuhiro、Misumi Toshihiro、Yamamoto Nobuyuki、Nakagawa Kazuhiko
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 28 Issue: 15 Pages: 3207-3213
- DOI
  10.1158/1078-0432.ccr-22-0602
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07175
[Journal Article] Differential properties of KRAS transversion and transition mutations in non-small cell?lung cancer: associations with environmental factors and clinical outcomes2022
- Author(s)
  Sato Koichi、Akamatsu Hiroaki、Koh Yasuhiro、Ogawa Koichi、Isa Shun-ichi、Ando Masahiko、Tamiya Akihiro、Kubo Akihito、Kitagawa Chiyoe、Kawaguchi Tomoya、Yamamoto Nobuyuki
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1
- DOI
  10.1186/s12885-022-10246-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07175
[Journal Article] Phase Ib Study of Osimertinib Plus Ramucirumab in Japanese Lung Cancer Patients With EGFR Mutation2021
- Author(s)
  AKAMATSU HIROAKI、OZAWA YUICHI、OYANAGI JUN、FUJIMOTO DAICHI、HATA AKITO、KATAKAMI NOBUYUKI、TOMII KEISUKE、MURAKAMI ERIKO、SUGIMOTO TAKEYA、SHIMOKAWA TOSHIO、KOH YASUHIRO、YAMAMOTO NOBUYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 2 Pages: 911-917
- DOI
  10.21873/anticanres.14844
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Sequential therapy of crizotinib followed by alectinib for non-small cell lung cancer harbouring anaplastic lymphoma kinase rearrangement (WJOG9516L): A multicenter retrospective cohort study2021
- Author(s)
  Ito Kentaro, Yamanaka Takeharu, Fujimoto Daichi, Maeno Ken, Aoki Takuya, Miura Satoru, Akamatsu Hiroaki、Nakagawa Kazuhiko, Yamamoto Nobuyuki
- Journal Title
  
  European Journal of Cancer
  
  Volume: 145 Pages: 183-193
- DOI
  10.1016/j.ejca.2020.12.026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Efficacy of Osimertinib Plus Bevacizumab vs Osimertinib in Patients With EGFR T790M?Mutated Non?Small Cell Lung Cancer Previously Treated With Epidermal Growth Factor Receptor?Tyrosine Kinase Inhibitor2021
- Author(s)
  Akamatsu Hiroaki、Toi Yukihiro、Hayashi Hidetoshi、Fujimoto Daichi、Tachihara Motoko、Furuya Naoki、Otani Sakiko、Shimizu Junichi、Katakami Nobuyuki、Azuma Koichi、Miura Naoko、Nishino Kazumi、Hara Satoshi、Teraoka Shunsuke、Morita Satoshi、Nakagawa Kazuhiko、Yamamoto Nobuyuki
- Journal Title
  
  JAMA Oncology
  
  Volume: 7 Issue: 3 Pages: 386-386
- DOI
  10.1001/jamaoncol.2020.6758
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] CD24, not CD47, negatively impacts upon response to PD‐1/L1 inhibitors in non?small‐cell lung cancer with PD‐L1 tumor proportion score?<?502020
- Author(s)
  Ozawa Yuichi、Harutani Yuhei、Oyanagi Jun、Akamatsu Hiroaki、Fukuoka Junya、Nakanishi Masanori、Koh Yasuhiro、Yamamoto Nobuyuki
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 1 Pages: 72-80
- DOI
  10.1111/cas.14705
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Differential significance of molecular subtypes which were classified into EGFR exon 19 deletion on the first line afatinib monotherapy2020
- Author(s)
  Tokudome Nahomi、Koh Yasuhiro、Akamatsu Hiroaki、Fujimoto Daichi、Okamoto Isamu、Nakagawa Kazuhiko、Hida Toyoaki、Imamura Fumio、Morita Satoshi、Yamamoto Nobuyuki
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Issue: 1 Pages: 103-103
- DOI
  10.1186/s12885-020-6593-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Predicting osimertinib‐treatment outcomes through EGFR mutant‐fraction monitoring in the circulating tumor DNA of EGFR T790M‐positive patients with non‐small cell lung cancer (WJOG8815L)2020
- Author(s)
  Sakai Kazuko、Takahama Takayuki、Shimokawa Mototsugu、Azuma Koichi、Takeda Masayuki、Kato Terufumi、Daga Haruko、Okamoto Isamu、Akamatsu Hiroaki、Teraoka Shunsuke、Ono Akira、Ohira Tatsuo、Yokoyama Toshihide、Yamamoto Nobuyuki、Nakagawa Kazuhiko、Nishio Kazuto
- Journal Title
  
  Molecular Oncology
  
  Volume: 15 Issue: 1 Pages: 126-137
- DOI
  10.1002/1878-0261.12841
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Detection of AXL expression in circulating tumor cells of lung cancer patients using an automated microcavity array system2020
- Author(s)
  Ikeda Mio、Koh Yasuhiro、Teraoka Shunsuke、Sato Koichi、Kanai Kuninobu、Hayata Atsushi、Tokudome Nahomi、Akamatsu Hiroaki、Ozawa Yuichi、Akamatsu Keiichiro、Endo Katsuya、Higuchi Masayuki、Nakanishi Masanori、Ueda Hiroki、Yamamoto Nobuyuki
- Journal Title
  
  Cancer Medicine
  
  Volume: 9 Issue: 6 Pages: 2122-2133
- DOI
  10.1002/cam4.2846
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Plasma screening for the T790M mutation of EGFR and phase 2 study of osimertinib efficacy in plasma T790M?positive non?small cell lung cancer: West Japan Oncology Group 8815L/LPS study2020
- Author(s)
  Takahama Takayuki、Akamatsu Hiroaki、Teraoka Shunsuke、Takahashi Toshiaki、Ono Akira、Ohira Tatsuo、Yokoyama Toshihide、Sakai Kazuko、Yamamoto Nobuyuki、Nishio Kazuto、Nakagawa Kazuhiko
- Journal Title
  
  Cancer
  
  Volume: 126 Issue: 9 Pages: 1940-1948
- DOI
  10.1002/cncr.32749
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Tumor mutation burden as a biomarker for lung cancer patients treated with pemetrexed and cisplatin (the JIPANG-TR).2020
- Author(s)
  Sakai K, Tsuboi M, Kenmotsu H, Yamanaka T, Takahashi T, Goto K, Daga H, Ohira T, Ueno T, Aoki T, Nakagawa K, Yamazaki K, Hosomi Y, Kawaguchi K, Okumura N, Takiguchi Y, Sekine A, Haruki T, Yamamoto H, Sato Y, Sugio K
- Journal Title
  
  Cancer Sci.
  
  Volume: 112(1) Issue: 1 Pages: 388-396
- DOI
  10.1111/cas.14730
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09168, KAKENHI-PROJECT-18K07271, KAKENHI-PROJECT-20K08561
[Journal Article] Predictive and sensitive biomarkers for thyroid dysfunctions during treatment with immune‐checkpoint inhibitors2020
- Author(s)
  Kurimoto Chiaki、Inaba Hidefumi、Ariyasu Hiroyuki、Iwakura Hiroshi、Ueda Yoko、Uraki Shinsuke、Takeshima Ken、Furukawa Yasushi、Morita Shuhei、Yamamoto Yuki、Yamashita Shimpei、Katsuda Masahiro、Hayata Atsushi、Akamatsu Hiroaki、Jinnin Masatoshi、Hara Isao、Yamaue Hiroki、Akamizu Takashi
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 5 Pages: 1468-1477
- DOI
  10.1111/cas.14363
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271, KAKENHI-PROJECT-20K11514, KAKENHI-PROJECT-20K17541, KAKENHI-PROJECT-17H01580
[Journal Article] Survival Analysis for Patients with ALK Rearrangement‐Positive Non‐Small Cell Lung Cancer and a Poor Performance Status Treated with Alectinib: Updated Results of Lung Oncology Group in Kyushu 14012019
- Author(s)
  Iwama Eiji、Akamatsu Hiroaki、Morinaga Ryotaro、Akagi Takanori、Shimose Takayuki、Tokunaga Shoji、Yamamoto Nobuyuki、Nakanishi Yoichi、Sugio Kenji、Okamoto Isamu
- Journal Title
  
  The Oncologist
  
  Volume: 25 Issue: 4 Pages: 306-306
- DOI
  10.1634/theoncologist.2019-0728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Carboplatin Plus Nab-paclitaxel in Performance Status 2 Patients With Advanced Non-small-cell Lung Cancer.2019
- Author(s)
  Nakashima K, Akamatsu H, Murakami H, Niwa T, Iwamoto Y, Ozawa Y, Yokoyama T, Shoda H, Yamamoto N, Yoshioka H, Masuda K, Naito T, Mori K, Takahashi T.
- Journal Title
  
  Anticancer Res.
  
  Volume: 39 Issue: 3 Pages: 1463-1468
- DOI
  10.21873/anticanres.13263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Genetic Profiling of Non‐Small Cell Lung Cancer at Development of Resistance to First‐ or Second‐Generation EGFR‐TKIs by CAPP‐Seq Analysis of Circulating Tumor DNA2019
- Author(s)
  Otsubo Kohei、Sakai Kazuko、Takeshita Masafumi、Harada Daijiro、Azuma Koichi、Ota Keiichi、Akamatsu Hiroaki、Goto Koichi、Horiike Atsushi、Kurata Takayasu、Nakagaki Noriaki、Nosaki Kaname、Iwama Eiji、Nakanishi Yoichi、Nishio Kazuto、Okamoto Isamu
- Journal Title
  
  The Oncologist
  
  Volume: 24 Issue: 8 Pages: 1022-1026
- DOI
  10.1634/theoncologist.2019-0101
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271, KAKENHI-PROJECT-18K15214
[Journal Article] Phase I safety and pharmacokinetics study of rovalpituzumab tesirine in Japanese patients with advanced, recurrent small cell lung cancer2019
- Author(s)
  Udagawa Hibiki、Akamatsu Hiroaki、Tanaka Kentaro、Takeda Masayuki、Kanda Shintaro、Kirita Keisuke、Teraoka Shunsuke、Nakagawa Kazuhiko、Fujiwara Yutaka、Yasuda Ikuko、Okubo Sumiko、Shintani Masayuki、Kosloski Matthew P.、Scripture Charity、Tamura Tomohide、Okamoto Isamu
- Journal Title
  
  Lung Cancer
  
  Volume: 135 Pages: 145-150
- DOI
  10.1016/j.lungcan.2019.07.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Subgroup Analysis of Japanese Patients in a Phase III Study of Atezolizumab in Extensive-stage Small-cell Lung Cancer (IMpower133)2019
- Author(s)
  Nishio Makoto、Sugawara Shunichi、Atagi Shinji、Akamatsu Hiroaki、Sakai Hiroshi、Okamoto Isamu、Takayama Koichi、Hayashi Hidetoshi、Nakagawa Yuki、Kawakami Tomohisa
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 20 Issue: 6 Pages: 469-476.e1
- DOI
  10.1016/j.cllc.2019.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] The Japanese Lung Cancer Society Guideline for Non-Small Cell Lung Cancer, Stage IV2019
- Author(s)
  Akamatsu H, Maemondo M, Seto T, Yamamoto N.
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 24 Pages: 731-770
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Summary of the Japanese Respiratory Society statement for the treatment of lung cancer with comorbid interstitial pneumonia2019
- Author(s)
  Ogura Takashi、Akamatsu Hiroaki、Kenmotsu Hirotsugu、Yanagihara Toyoshi、Yamamoto Nobuyuki、Yamamoto Hiromasa、Gaga Mina、Fong Kwun M.、Powell Charles A.、Kiura Katsuyuki
- Journal Title
  
  Respiratory Investigation
  
  Volume: 57 Issue: 6 Pages: 512-533
- DOI
  10.1016/j.resinv.2019.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] The impact of high PD-L1 expression on the surrogate endpoints and clinical outcomes of anti-PD-1/PD-L1 antibodies in non-small cell lung cancer.2019
- Author(s)
  Ito K, Miura S, Sakaguchi T, Murotani K, Horita N, Akamatsu H, Uemura K, Morita S, Yamamoto N.
- Journal Title
  
  Lung Cancer
  
  Volume: 128 Pages: 113-119
- DOI
  10.1016/j.lungcan.2018.12.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09620, KAKENHI-PROJECT-18K07271
[Journal Article] Predictive value of serum protein levels in patients with advanced non-small cell lung cancer treated with nivolumab2019
- Author(s)
  Oyanagi Jun、Koh Yasuhiro、Sato Koichi、Mori Keita、Teraoka Shunsuke、Akamatsu Hiroaki、Kanai Kuninobu、Hayata Atsushi、Tokudome Nahomi、Akamatsu Keiichiro、Nakanishi Masanori、Ueda Hiroki、Yamamoto Nobuyuki
- Journal Title
  
  Lung Cancer
  
  Volume: 132 Pages: 107-113
- DOI
  10.1016/j.lungcan.2019.03.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Clinical significance of monitoring EGFR mutation in plasma using multiplexed digital PCR in EGFR mutated patients treated with afatinib (West Japan Oncology Group 8114LTR study).2019
- Author(s)
  Akamatsu H, Yasuhiro Koh, Isamu Okamoto, Daichi Fujimoto, Akihiro Bessho, Koichi Azuma, Satoshi Morita, Nobuyuki Yamamoto, Kazuhiko Nakagawa
- Journal Title
  
  Lung Cancer.
  
  Volume: 131 Pages: 128-133
- DOI
  10.1016/j.lungcan.2019.03.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Furosemide versus mannitol in Japanese patients with thoracic malignancy who received cisplatin-based chemotherapy using short hydration: study protocol for a randomised controlled trial2019
- Author(s)
  Murakami Eriko、Akamatsu Hiroaki、Shimokawa Toshio、Wada Kiyoko、Yamamoto Nobuyuki
- Journal Title
  
  BMJ Open
  
  Volume: 9 Issue: 12 Pages: e029057-e029057
- DOI
  10.1136/bmjopen-2019-029057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271, KAKENHI-PROJECT-15K00044
[Journal Article] Heterogeneous Expression of Programmed Death Receptor-ligand 1 on Circulating Tumor Cells in Patients With Lung Cancer.2019
- Author(s)
  Koh H, Yagi S, Akamatsu H, Kanai K, Hayata A, Tokudome N, Akamatsu K, Higuchi M, Kanbara H, Nakanishi M, Ueda H, Yamamoto N.
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 印刷中 Issue: 4 Pages: 270-277.e1
- DOI
  10.1016/j.cllc.2019.03.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] A Phase II Study of Nivolumab in Patients With Advanced Non-small-cell Lung Cancer who Responded to Prior PD-1/L1 Inhibitors: West Japan Oncology Group 9616L (WJOG9616L).2019
- Author(s)
  Akamatsu H, Teraoka S, Koh Y, Yamanaka T, Yamamoto N, Nakagawa K.
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 20 Issue: 2 Pages: 139-141
- DOI
  10.1016/j.cllc.2018.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Phase I/II Study of Osimertinib With Bevacizumab in EGFR-mutated, T790M-positive Patients With Progressed EGFR-TKIs: West Japan Oncology Group 8715L (WJOG8715L)2019
- Author(s)
  Akamatsu Hiroaki、Teraoka Shunsuke、Morita Satoshi、Katakami Nobuyuki、Tachihara Motoko、Daga Haruko、Yamamoto Nobuyuki、Nakagawa Kazuhiko
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 20 Issue: 4 Pages: e492-e494
- DOI
  10.1016/j.cllc.2019.03.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] A Phase II Study of Gefitinib With Concurrent Thoracic Radiotherapy in Patients With Unresectable, Stage III Non-small-cell Lung Cancer Harboring EGFR Mutations (WJOG6911L).2019
- Author(s)
  Akamatsu H, Harada H, Tokunaga S, Yoshimura N, Ikeda H, Oizumi S, Sugimoto N, Takano T, Murakami H, Nishimura Y, Yamamoto N, Nakagawa K.
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 20 Issue: 1 Pages: e25-e27
- DOI
  10.1016/j.cllc.2018.08.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Immune‐Related Adverse Events by Immune Checkpoint Inhibitors Significantly Predict Durable Efficacy Even in Responders with Advanced Non‐Small Cell Lung Cancer2019
- Author(s)
  Akamatsu Hiroaki、Murakami Eriko、Oyanagi Jun、Shibaki Ryota、Kaki Takahiro、Takase Eri、Tanaka Masanori、Harutani Yuhei、Yamagata Nao、Okuda Yuka、Furuta Katsuyuki、Sugimoto Takeya、Teraoka Shunsuke、Hayata Atsushi、Tokudome Nahomi、Ozawa Yuichi、Mori Keita、Koh Yasuhiro、Yamamoto Nobuyuki
- Journal Title
  
  The Oncologist
  
  Volume: 25 Issue: 4 Pages: e679-e683
- DOI
  10.1634/theoncologist.2019-0299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Osimertinib for patients with EGFR T790M mutation-positive non-small-cell lung cancer and a poor performance status.2019
- Author(s)
  Nakashima K, Kimura M, Akamatsu H, Daga H, Imai H, Taira T, Ko R, Hisamatsu Y, Nishino K, Sugimoto T, Miyashita Y, Takahashi T.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 印刷中 Issue: 7 Pages: 671-675
- DOI
  10.1093/jjco/hyz041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Genetic Profiling of Non-Small Cell Lung Cancer at Development of Resistance to First- or Second-Generation EGFR-TKIs by CAPP-Seq Analysis of Circulating Tumor DNA.2019
- Author(s)
  Otsubo K, Sakai,K, Takeshita M, Harada D, Azuma K, Ota K, Akamatsu H, Goto K, Horiike A, Kurata T, Nakagaki N, Nosaki K, Iwama E, Nakanishi Y, Nishio N, Okamoto I.
- Journal Title
  
  The Oncologist
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Exploration of resistance mechanisms for epidermal growth factor receptor-tyrosine kinase inhibitors based on plasma analysis by digital polymerase chain reaction and next-generation sequencing.2018
- Author(s)
  Iwama E, Sakai K, Azuma K, Harada D, Nosaki K, Hotta K, Nishio M, Kurata T, Fukuhara T, Akamatsu H, Goto K, Shimose T, Kishimoto J, Nakanishi Y, Nishio K, Okamoto I.
- Journal Title
  
  Cancer Sci
  
  Volume: 109 Issue: 12 Pages: 3921-3933
- DOI
  10.1111/cas.13820
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271, KAKENHI-PROJECT-18K15214, KAKENHI-PLANNED-17H06404
[Journal Article] Osimertinib With Ramucirumab in EGFR-mutated, T790M-positive Patients With Progression During EGFR-TKI Therapy: Phase Ib Study2018
- Author(s)
  Akamatsu H, Koh Y, Ozawa Y, Fujimoto D, Hata A, Katakami N, Tomii K, Shimokawa T, Yamamoto N.
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 19 Issue: 6 Pages: e871-e874
- DOI
  10.1016/j.cllc.2018.08.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K00044, KAKENHI-PROJECT-18K07271
[Journal Article] Osimertinib in Japanese patients with EGFR T790M mutation-positive advanced non-small-cell lung cancer: AURA3 trial.2018
- Author(s)
  Akamatsu H, Katakami N, Okamoto I, Kato T, Kim YH, Imamura F, Shinkai M, Hodge RA, Uchida H, Hida T.
- Journal Title
  
  Lung Cancer
  
  Volume: 109 Issue: 6 Pages: 1930-1938
- DOI
  10.1111/cas.13623
- NAID
  120006496875
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] EGFR mutation analysis for prospective patient selection in AURA3 phase III trial of osimertinib versus platinum-pemetrexed in patients with EGFR T790M-positive advanced non-small-cell lung cancer.2018
- Author(s)
  John T, Akamatsu H, Delmonte A, Su WC, Lee JS, Chang GC, Huang X, Jenkins S, Wu YL.
- Journal Title
  
  Lung Cancer
  
  Volume: 126 Pages: 133-138
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Nivolumab induced radiation recall pneumonitis after two years of radiotherapy.2017
- Author(s)
  Shibaki R, Akamatsu H, Koh Y, et al.
- Journal Title
  
  Annals of Oncology
  
  Volume: epub Issue: 6 Pages: 1404-1405
- DOI
  10.1093/annonc/mdx115
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19464, KAKENHI-PROJECT-15K06878, KAKENHI-PROJECT-15K09226
[Journal Article] Alectinib for Patients with ALK Rearrangement-Positive Non-Small Cell Lung Cancer and a Poor Performance Status (Lung Oncology Group in Kyushu 1401).2017
- Author(s)
  Iwama E, Goto Y, Akamatsu H, et al.
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 17 Issue: 7 Pages: 30123-5
- DOI
  10.1016/j.jtho.2017.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19464, KAKENHI-PROJECT-15K09226
[Journal Article] Osimertinib or Platinum-Pemetrexed in EGFR T790M-Positive Lung Cancer.2017
- Author(s)
  Mok TS, Wu Y-L, Akamatsu H, et al.
- Journal Title
  
  New England Journal of Medicine
  
  Volume: 7 Issue: 7 Pages: 629-640
- DOI
  10.1056/nejmoa1612674
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19464
[Journal Article] Correlation between immune-related adverse events and efficacy in non-small cell lung cancer treated with nivolumab.2017
- Author(s)
  Sato K
- Journal Title
  
  Lung Cancer
  
  Volume: 115 Pages: 71-74
- DOI
  10.1016/j.lungcan.2017.11.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06878, KAKENHI-PROJECT-15K09226, KAKENHI-PROJECT-16K19464
[Journal Article] Detection of the T790M mutation of EGFR in plasma of advanced non-small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors (West Japan oncology group 8014LTR study)2016
- Author(s)
  Takahama T, Sakai K, Takeda M, Azuma K, Hida T, Hirabayashi M, Oguri T, Tanaka H, Ebi N, Sawa T, Bessho A, Tachihara M, Akamatsu H, Bandoh S, Himeji D, Ohira T, Shimokawa M, Nakanishi Y, Nakagawa K, Nishio K.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 36 Pages: 58492-58499
- DOI
  10.18632/oncotarget.11303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462138, KAKENHI-PROJECT-16K19464
[Journal Article] Applicability of the Japanese equation for estimating glomerular filtration rate in patients with advanced-stage thoracic cancer.2016
- Author(s)
  Kikuchi T, Akamatsu H, Mori K, Tanaka A, Kanai K, Hayata A, Tokudome N, Akamatsu K, Koh Y, Nakanishi M, Ueda H, Yamamoto N
- Journal Title
  
  Respiratory Investigation
  
  Volume: 54 Issue: 6 Pages: 479-483
- DOI
  10.1016/j.resinv.2016.05.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K18456, KAKENHI-PROJECT-16K19464
[Journal Article] The efficacy of amrubicin on central nervous system metastases originating from small-cell lung cancer: a case series of eight patients.2015
- Author(s)
  Miura S, Kaira K, Kaira R, Akamatsu H, Ono A, Shukuya T, Tsuya A, Nakamura Y, Kenmotsu H, Naito T, Murakami H, Takahashi T, Endo M, Yamamoto N.
- Journal Title
  
  Invest New Drugs.
  
  Volume: epub ahead of print
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Prognostic significance of diabetes mellitus in locally advanced non-small cell lung cancer.2015
- Author(s)
  Imai H, Kaira K, Mori K, Ono A, Akamatsu H, et al.
- Journal Title
  
  BMC Cancer
  
  Volume: 15 Issue: 1 Pages: 989-989
- DOI
  10.1186/s12885-015-2012-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] The effect of gefitinib in patients with postoperative recurrent non-small cell lung cancer harboring mutations of the epidermal growth factor receptor.2015
- Author(s)
  Ko R, Kenmotsu H, Akamatsu H, et al.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 20(4) Issue: 4 Pages: 668-73
- DOI
  10.1007/s10147-014-0761-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Comparison of platinum combination re-challenge therapy and docetaxel monotherapy in non-small cell lung cancer patients previously treated with platinum-based chemoradiotherapy.2015
- Author(s)
  Imai H, Kaira K, Akamatsu H, et al.
- Journal Title
  
  Springerplus.
  
  Volume: 31:4 Issue: 1 Pages: 152-152
- DOI
  10.1186/s40064-015-0929-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Disease flare after gefitinib discontinuation2015
- Author(s)
  Hiroaki Akamatsu
- Journal Title
  
  Respir Investig
  
  Volume: 53 Pages: 68-72
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Journal Article] Prognostic impact of cancer cachexia in patients with advanced non-small cell lung cancer.2015
- Author(s)
  Kimura M, Naito T, Kenmotsu H, Taira T, Wakuda K, Oyakawa T, Hisamatsu Y, Tokito T, Imai H, Akamatsu H, Ono A, Kaira K, Murakami H, Endo M, Mori K, Takahashi T, Yamamoto N.
- Journal Title
  
  Support Care Cancer
  
  Volume: 23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Progression of Irreversible Airflow Limitation in Asthma: Correlation with Severe Exacerbations2015
- Author(s)
  Matsunaga K, Hirano T, Oka A, Tanaka A, Kanai K, Kikuchi T, Hayata A, Akamatsu H, Akamatsu K, Koh Y, Nakanishi M, Minakata Y, Yamamoto N
- Journal Title
  
  J Allergy Clin Immunol Pract
  
  Volume: 3 Issue: 5 Pages: 759-764
- DOI
  10.1016/j.jaip.2015.05.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09187, KAKENHI-PROJECT-26461489, KAKENHI-PROJECT-25461502, KAKENHI-PROJECT-26870509
[Journal Article] The efficacy of amrubicin on central nervous system metastases originating from small-cell lung cancer: a case series of eight patients.2015
- Author(s)
  Miura S, Kaira K, Akamatsu H, et al.
- Journal Title
  
  Invest New Drugs.
  
  Volume: 33(3) Issue: 3 Pages: 55-60
- DOI
  10.1007/s10637-015-0233-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Disease flare after gefitinib discontinuation.2015
- Author(s)
  Akamatsu H, Ono A, Shukuya T, Tsuya A, Nakamura Y, Kenmotsu H, Naito T, Murakami H, Endo M, Nakajima T, Yamamoto N
- Journal Title
  
  Respir Investig
  
  Volume: 53 Pages: 68-72
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Disease flare after gefitinib discontinuation.2015
- Author(s)
  Akamatsu H, Ono A, Shukuya T
- Journal Title
  
  Respir Investig.
  
  Volume: 53(2) Issue: 2 Pages: 68-72
- DOI
  10.1016/j.resinv.2014.10.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Comparison of platinum combination re-challenge therapy and docetaxel monotherapy in non-small cell lung cancer patients previously treated with platinum-based chemoradiotherapy.2015
- Author(s)
  Imai H, Kaira K, Mori K, Ono A, Akamatsu H, Taira T, Yoshino R, Kenmotsu H, Saitoh J, Harada H, Naito T, Murakami H, Tomizawa Y, Matsuura M, Saito R, Nakajima T, Yamada M, Takahashi T.
- Journal Title
  
  Springerplus
  
  Volume: 4 Pages: 152-152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Progression-free survival, post-progression survival, and tumor response as surrogate markers for overall survival in patients with extensive small cell lung cancer.2015
- Author(s)
  Imai H, Mori K, Wakuda K, Ono A, Akamatsu H, Shukuya T, Taira T, Kenmotsu H, Naito T, Kaira K, Murakami H, Endo M, Nakajima T, Yamamoto N, Takahashi T.
- Journal Title
  
  Ann Thorac Med.
  
  Volume: 10 Pages: 61-65
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Progression-free survival, post-progression survival, and tumor response as surrogate markers for overall survival in patients with extensive small cell lung cancer.2015
- Author(s)
  Imai H, Mori K, Wakuda K, Ono A, Akamatsu H,
- Journal Title
  
  Ann Thorac Med.
  
  Volume: 10(1) Pages: 61-66
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Prognostic impact of cancer cachexia in patients with advanced non-small cell lung cancer.2015
- Author(s)
  Kimura M, Naito T, Akamatsu H, et al.
- Journal Title
  
  Support Care Cancer.
  
  Volume: 23(6) Issue: 6 Pages: 1699-708
- DOI
  10.1007/s00520-014-2534-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Changes in forced expiratory volume in 1 second over time in patients with controlled asthma at baseline.2014
- Author(s)
  Matsunaga K, Ichikawa T, Oka A, Morishita Y, Kanai K, Hiramatsu M, Akamatsu H, Kawabata H, Kikuchi T, Akamatsu K, Hirano T, Kou Y, Nakanishi M, Minakata Y, Yamamoto N.
- Journal Title
  
  Respir Med
  
  Volume: 108 Pages: 976-982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Multiplexed molecular profiling of lung cancer using pleural effusion2014
- Author(s)
  Akamatsu H, Koh Y, Kenmotsu H, Naito T, Serizawa M, Kimura M, Mori K, Imai H, Ono A, Shukuya T, Taira T, Murakami H, Ohde Y, Endo M, Nakajima T, Takahashi T, Yamamoto N
- Journal Title
  
  J Thorac Oncol
  
  Volume: 9 Pages: 1048-1052
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Identification of actionable mutations in malignant pleural mesothelioma.2014
- Author(s)
  Shukuya T, Serizawa M, Watanabe M, Akamatsu H, Abe M, Imai H, Tokito T, Ono A, Taira T, Kenmotsu H, Naito T, Murakami H, Takahashi T, Endo M, Ohde Y, Nakajima T, Yamamoto N, Koh Y.
- Journal Title
  
  Lung Cancer
  
  Volume: 86 Pages: 35-40
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Identification of actionable mutations in malignant pleural mesothelioma2014
- Author(s)
  Takehito Shukuya
- Journal Title
  
  Lung Cancer
  
  Volume: 86 Issue: 1 Pages: 35-40
- DOI
  10.1016/j.lungcan.2014.08.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501363, KAKENHI-PROJECT-24591186, KAKENHI-PROJECT-25860658, KAKENHI-PROJECT-26870509
[Journal Article] Toxicity and efficacy of chemotherapy for non-small cell lung cancer with cavitary lesions.2014
- Author(s)
  Tokito T, Shukuya T, Akamatsu H, Ono A, Taira T, Kenmotsu H, Naito T, Murakami H, Takahashi T, Endo M, Mori K, Yamamoto N.
- Journal Title
  
  Respir Investig
  
  Volume: 52
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Assessment of mutational profile of Japanese lung adenocarcinoma patients by multitarget assays: a prospective, single-institute study.2014
- Author(s)
  Serizawa M, Koh Y, Kenmotsu H, Isaka M, Murakami H, Akamatsu H, Mori K, Abe M, Hayashi I, Taira T, Maniwa T, Takahashi T, Endo M, Nakajima T, Ohde Y, Yamamoto N.
- Journal Title
  
  Cancer
  
  Volume: 15 Pages: 1471-81
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] The effect of gefitinib in patients with postoperative recurrent non-small cell lung cancer harboring mutations of the epidermal growth factor receptor.2014
- Author(s)
  Ko R, Kenmotsu H, Hisamatsu Y, Akamatsu H, Omori S, Nakashima K, Oyakawa T, Wakuda K, Shukuya T, Ono A, Imai H, Taira T, Naito T, Murakami H, Mori K, Endo M, Ohde Y, Takahashi K, Takahashi T.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: epub ahead of print
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Individual-level data on the relationships of progression-free survival and post-progression survival with overall survival in patients with advanced non-squamous non-small cell lung cancer patients who received second-line chemotherapy.2014
- Author(s)
  Imai H, Mori K, Ono A, Akamatsu H, Taira T, Kenmotsu H, Naito T, Kaira K, Murakami H, Endo M, Nakajima T, Takahashi T.
- Journal Title
  
  Med Oncol
  
  Volume: 31 Pages: 88-88
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Comparison of cisplatin plus pemetrexed and cisplatin plus gemcitabine for the treatment of malignant pleural mesothelioma in Japanese patients.2014
- Author(s)
  Shukuya T, Takahashi T, Imai H, Tokito T, Ono A, Akamatsu H, Taira T, Kenmotsu H, Naito T, Murakami H, Endo M, Yamamoto N.
- Journal Title
  
  Respir Investig
  
  Volume: 52 Pages: 101-106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Patent] METHOD FOR PREDICTING THE DURABLE EFFICACY OF EGFR TYROSINE KINASES INHIBITORS IN EGFR-MUTATED NON-SMALL LUNG CANCER2017
- Inventor(s)
  山本信之、洪泰浩、赤松弘朗
- Industrial Property Rights Holder
  山本信之、洪泰浩、赤松弘朗
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] ドライバー変異陽性患者における周術期薬物療法2021
- Author(s)
  赤松弘朗
- Organizer
  第60回日本呼吸器学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] HER2 missense mutations in breast cancer cells do not alter HER2 internalization or sensitivity to T-DM12020
- Author(s)
  Hiroaki Akamatsu, Rosa Mino, Marcel Mettlen, Dan Ye, Dhivya R. Sudhan, Albert Lin, Arnaldo Marin, Alberto Servetto, Kyung-min Lee, Sumanta Chatterjee, Sandra L. Schmid, Carlos L. Arteaga and Ariella B. Hanker
- Organizer
  AACR Annual Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] EGFR遺伝子変異陽性肺腺癌に対するオシメルチニブ＋ラムシルマブの第I相試験（医師主導治験）2019
- Author(s)
  小澤雄一、赤松弘朗、洪泰浩、山本信之
- Organizer
  肺癌学会2019
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] Predictive impact of sequential evaluation of PD-L1-expressing circulating tumor cells in NSCLC patients treated with nivolumab.2018
- Author(s)
  Koh Y, Akamatsu H, Mori K, Kanai K, Hayata A, Tokudome N, Higuchi M, Akamatsu K, Nakanishi M, Ueda H, Yamamoto N
- Organizer
  American Association for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] がん免疫療法ガイドライン改訂版2018
- Author(s)
  赤松弘朗
- Organizer
  第16回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] 肺癌診療ガイドライン改訂の要点2018
- Author(s)
  赤松弘朗
- Organizer
  第58回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] Predictive values of serum protein levels in advanced non-small-cell lung cancer patients treated with nivolumab.2018
- Author(s)
  Oyanagi J, Koh Y, Akamatsu H, Kanai K, Hayata A, Tokudome N, Akamatsu K, Nakanishi M, Ueda H, Yamamoto N:
- Organizer
  American Association for Cancer Research Annual Meeting
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] 肺癌薬物療法アップデート肺がんの薬物療法2018
- Author(s)
  赤松弘朗
- Organizer
  第16回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] Sequential tracking of PD-L1 expression on circulating tumor cells in NSCLC patients treated with nivolumab.2017
- Author(s)
  Akamatsu H, Koh Y, Yamamoto N, et al.
- Organizer
  EORTC-NCI-AACR meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19464
[Presentation] Predictive impact of PD-L1-expressing circulating tumor cells in NSCLC patients treated with nivolumab.2017
- Author(s)
  Shibaki R, Akamatsu H, Koh Y, Yamamoto N, et al.
- Organizer
  2017 American Society of Clinical Oncology
- Place of Presentation
  Chicago, USA
- Year and Date
  2017-06-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19464
[Presentation] PD-L1 expression on circulating tumor cells and its comparison with tumor tissues in Japanese lung cancer patients.2017
- Author(s)
  Akamatsu H
- Organizer
  AACR 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] Sequential tracking of PD-L1 expression on circulating tumor cells in NSCLC patients treated with nivolumab2017
- Author(s)
  Akamatsu H
- Organizer
  AACR-NCI-EORTC 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] Correlation Between Immune-Related Adverse Events and Efficacy in Non-Small Cell Lung Cancer Treated with Nivolumab.2017
- Author(s)
  Sato K, Akamatsu H, Murakami E, et al.
- Organizer
  World Conference on Lung Cancer 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19464
[Presentation] A prospective biomarker study using digital PCR method in EGFR mutated, advanced lung adenocarcinoma patients treated with afatinib2016
- Author(s)
  Akamatsu H
- Organizer
  American Association for Cancer Research Annual Meeting 2016
- Place of Presentation
  New Orleans, Louisiana, USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] Ongoing early phase trials using liquid biopsy2015
- Author(s)
  Hiroaki Akamatsu
- Organizer
  The 4th Japan-Taiwan Oncology Phase I Trial Conference
- Place of Presentation
  International Conference Center of National Taiwan University Hospital
- Year and Date
  2015-04-26
- Invited
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] stablishment of novel multiplexed assay to detect EGFR mutations using ultra-sensitive digital PCR2015
- Author(s)
  Hiroaki Akamatsu
- Organizer
  ESMO Asia
- Place of Presentation
  Singapore
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] Establishment of multiplexed ultra-sensitive detection of epidermal growth factor receptor mutations using picodroplet digital PCR.2015
- Author(s)
  赤松弘朗、洪泰浩、山本信之ら
- Organizer
  American Association for Cancer Research Annual Meeting 2015
- Place of Presentation
  Pennsylvania convention center, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] Establishment of multiplexed ultra-sensitive detection of epidermal growth factor receptor mutations using picodroplet digital PCR2015
- Author(s)
  Hiroaki Akamatsu, Yasuhiro Koh, Masaru Watanabe, Takashi Kikuchi, Masanori Nakanishi, Kazuto Matsunaga, Nobuyuki Yamamoto.
- Organizer
  American Association of Cancer Research Annual Meeting 2015
- Place of Presentation
  Pennsylvania Convention Center
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] Establishment of multiplexed ultra-sensitive detection of epidermal growth factor receptor mutations using picodroplet digital PCR2015
- Author(s)
  Hiroaki Akamatsu
- Organizer
  American Association for Cancer Research Annual Meeting 2015
- Place of Presentation
  Philadelphia, Pennsylvania, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] Establishment of novel multiplexed assay to detect EGFR mutations using ultra-sensitive digital PCR2015
- Author(s)
  赤松弘朗、洪泰浩、山本信之ら
- Organizer
  ESMO Asia 2015
- Place of Presentation
  Suntec, Singapore
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] Early Phase Trials Using Liquid Biopsy.2015
- Author(s)
  赤松弘朗
- Organizer
  4th Japan Taiwan Oncology Phase Ⅰ Trial Conference
- Place of Presentation
  NTUH International Convention Center, Taipei, Taiwan
- Year and Date
  2015-04-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] Droplet Digital PCR を用いた EGFR 遺伝子変異のマルチプレックス検出2014
- Author(s)
  渡辺勝、洪泰浩、赤松弘朗、菊池崇史、松永和人、山本信之
- Organizer
  日本肺癌学会総会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] Significance ofconsolidation chemotherapyin unresectable, locally advanced non-small cell lung cancer.2014
- Author(s)
  Hiroaki Akamatsu
- Organizer
  日本臨床腫瘍学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-26870509

1. YAMAMOTO Nobuyuki (60298966)

# of Collaborated Projects: 6 results

# of Collaborated Products: 57 results
2. KOH Yasuhiro (80426519)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
3. KIKUCHI Takashi (40649050)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 山口昌子 (00554536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 辻あさみ (60310794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 上田伊津代 (90530709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 藤本大智 (30895545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OHIRA Tatsuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. SHIMOKAWA Toshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 堀田信之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 杉尾賢二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 南方良章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 早田敦志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Akamatsu Hiroaki 赤松 弘朗

Research Projects

Research Products

Co-Researchers

マルチオミクス解析による免疫チェックポイント阻害剤低感受性肺癌の効果予測因子同定Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

小細胞肺癌における網羅的RNA解析と機械学習による免疫療法奏功予測パネルの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

分子標的治療を受ける進行肺がん患者の皮膚障害セルフケア困難の実態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Impact of tumor heterogeneity of driver mutation-positive lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploratory biomarker analysis to predict the efficacy of immune checkpoint inhibitors using cell-free DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Multiplex mutation detection using digital PCR method and its clinical utility

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploratory analyses of comprehensive and quantitative mutation profiling using cell-free DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] オンコロジークリニカルガイド 肺癌化学療法2019

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Total Pages

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Data Source

[Book] Medical Practice, 分子標的薬と血管新生阻害剤2019

Author(s)

Total Pages

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[Book] 呼吸器疾患最新の治療2019-20202019

Author(s)

Total Pages

Publisher

ISBN

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[Book] 肺癌診療ガイドライン 2018年版 第5版2018

Author(s)

Total Pages

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[Book] がん免疫療法ガイドライン 第2版2018

Author(s)

Total Pages

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ISBN

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[Book] どのような肺がん患者に化学療法が行われるか2016

Author(s)

Total Pages

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Data Source

[Book] 抗癌薬の副作用対策2016

Akamatsu Hiroaki 赤松弘朗

[Book] オンコロジークリニカルガイド肺癌化学療法2019

[Book] 肺癌診療ガイドライン 2018年版　第5版2018

[Book] がん免疫療法ガイドライン　第2版2018

[Book] 腫瘍病理鑑別診断アトラス肺癌2014

[Book] がん薬物療法の作用機序　殺細胞性抗悪性腫瘍薬　白金製剤･アルキル化薬･抗がん性抗生物質2014