Akamatsu Hiroaki 赤松弘朗

Researcher Number	10646582
Other IDs	https://orcid.org/0000-0001-5856-5512
Affiliation (Current)	2020: 和歌山県立医科大学, 医学部, 講師 2020: 静岡県立静岡がんセンター(研究所), その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2017 – 2018: 和歌山県立医科大学, 医学部, 講師 2014 – 2017: 和歌山県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Tumor therapeutics / Tumor diagnostics / Respiratory organ internal medicine / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator リキッドバイオプシー / EGFR遺伝子変異 / 肺がん / liquid biopsy / Liquid Biopsyに関する研究 / 肺癌 / immunotherapy / lung cancer / Liquid biopsy / 血中循環腫瘍細胞 … More Except Principal Investigator がん個別化医療 / 肺がん / リキッドバイオプシー / EGFR変異 / デジタルPCR / 分子標的治療 / EGFR / 新規診断技術 / 肺癌 Less

遺伝子変異陽性肺癌におけるheterogeneityが治療効果に与える影響の解明Principal InvestigatorOngoing
- Principal Investigator
  
  赤松弘朗
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Wakayama Medical University
Exploratory biomarker analysis to predict the efficacy of immune checkpoint inhibitors using cell-free DNAPrincipal Investigator
- Principal Investigator
  
  Akamatsu Hiroaki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Wakayama Medical University
Multiplex mutation detection using digital PCR method and its clinical utility
- Principal Investigator
  
  Yamamoto Nobuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Wakayama Medical University
Exploratory analyses of comprehensive and quantitative mutation profiling using cell-free DNAPrincipal Investigator
- Principal Investigator
  
  Akamatsu Hiroaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
  Tumor diagnostics
- Research Institution
  Wakayama Medical University

All 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book Patent

[Book] 肺癌診療ガイドライン 2018年版　第5版2018
- Author(s)
  赤松弘朗、山本信之、他
- Total Pages
  420
- Publisher
  金原出版
- ISBN
  9784307203913
- Data Source
  KAKENHI-PROJECT-18K07271
[Book] がん免疫療法ガイドライン　第2版2018
- Author(s)
  赤松弘朗、山本信之、他
- Total Pages
  162
- Publisher
  金原出版
- ISBN
  9784307101950
- Data Source
  KAKENHI-PROJECT-18K07271
[Book] 分子標的時代における治療推奨の重みづけをどうするか？2016
- Author(s)
  赤松弘朗, 山本信之
- Total Pages
  5
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K09226
[Book] どのような肺がん患者に化学療法が行われるか2016
- Author(s)
  赤松弘朗, 山本信之
- Total Pages
  6
- Publisher
  学研
- Data Source
  KAKENHI-PROJECT-15K09226
[Book] デジタルPCRの原理と臨床腫瘍学での有用性2016
- Author(s)
  赤松弘朗, 洪泰浩, 山本信之
- Total Pages
  5
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K09226
[Book] 各種がんにおける化学療法 1肺癌2016
- Author(s)
  赤松弘朗, 山本信之
- Total Pages
  6
- Publisher
  学研
- Data Source
  KAKENHI-PROJECT-15K09226
[Book] 抗癌薬の副作用対策2016
- Author(s)
  赤松弘朗, 山本信之
- Total Pages
  2
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-15K09226
[Book] 呼吸器疾患診療最新ガイドライン2014
- Author(s)
  菊池崇史, 赤松弘朗, 山本信之
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-26870509
[Book] EBMの手法による肺癌診療ガイドライン2014年版2014
- Author(s)
  赤松弘朗, 山本信之
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-26870509
[Book] 現在進行中の大規模無作為化比較試験2014
- Author(s)
  赤松弘朗, 山本信之
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-26870509
[Book] 腫瘍病理鑑別診断アトラス肺癌2014
- Author(s)
  赤松弘朗, 山本信之
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-26870509
[Book] がん薬物療法の作用機序　殺細胞性抗悪性腫瘍薬　白金製剤･アルキル化薬･抗がん性抗生物質2014
- Author(s)
  赤松弘朗, 山本信之
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26870509
[Book] Ⅲ期非小細胞肺癌の化学放射線療法.2014
- Author(s)
  赤松弘朗, 山本信之
- Publisher
  へるす出版
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] A Phase II Study of Gefitinib With Concurrent Thoracic Radiotherapy in Patients With Unresectable, Stage III Non-small-cell Lung Cancer Harboring EGFR Mutations (WJOG6911L).2019
- Author(s)
  Akamatsu H, Harada H, Tokunaga S, Yoshimura N, Ikeda H, Oizumi S, Sugimoto N, Takano T, Murakami H, Nishimura Y, Yamamoto N, Nakagawa K.
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 20
- DOI
  10.1016/j.cllc.2018.08.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] The impact of high PD-L1 expression on the surrogate endpoints and clinical outcomes of anti-PD-1/PD-L1 antibodies in non-small cell lung cancer.2019
- Author(s)
  Ito K, Miura S, Sakaguchi T, Murotani K, Horita N, Akamatsu H, Uemura K, Morita S, Yamamoto N.
- Journal Title
  
  Lung Cancer
  
  Volume: 128 Pages: 113-119
- DOI
  10.1016/j.lungcan.2018.12.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09620, KAKENHI-PROJECT-18K07271
[Journal Article] Carboplatin Plus Nab-paclitaxel in Performance Status 2 Patients With Advanced Non-small-cell Lung Cancer.2019
- Author(s)
  Nakashima K, Akamatsu H, Murakami H, Niwa T, Iwamoto Y, Ozawa Y, Yokoyama T, Shoda H, Yamamoto N, Yoshioka H, Masuda K, Naito T, Mori K, Takahashi T.
- Journal Title
  
  Anticancer Res.
  
  Volume: 39 Pages: 1463-1468
- DOI
  10.21873/anticanres.13263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Clinical significance of monitoring EGFR mutation in plasma using multiplexed digital PCR in EGFR mutated patients treated with afatinib (West Japan Oncology Group 8114LTR study).2019
- Author(s)
  Akamatsu H, Yasuhiro Koh, Isamu Okamoto, Daichi Fujimoto, Akihiro Bessho, Koichi Azuma, Satoshi Morita, Nobuyuki Yamamoto, Kazuhiko Nakagawa
- Journal Title
  
  Lung Cancer.
  
  Volume: 131 Pages: 128-133
- DOI
  10.1016/j.lungcan.2019.03.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Heterogeneous Expression of Programmed Death Receptor-ligand 1 on Circulating Tumor Cells in Patients With Lung Cancer.2019
- Author(s)
  Koh H, Yagi S, Akamatsu H, Kanai K, Hayata A, Tokudome N, Akamatsu K, Higuchi M, Kanbara H, Nakanishi M, Ueda H, Yamamoto N.
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 印刷中
- DOI
  10.1016/j.cllc.2019.03.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] A Phase II Study of Nivolumab in Patients With Advanced Non-small-cell Lung Cancer who Responded to Prior PD-1/L1 Inhibitors: West Japan Oncology Group 9616L (WJOG9616L).2019
- Author(s)
  Akamatsu H, Teraoka S, Koh Y, Yamanaka T, Yamamoto N, Nakagawa K.
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 20 Pages: 139-141
- DOI
  10.1016/j.cllc.2018.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Osimertinib for patients with EGFR T790M mutation-positive non-small-cell lung cancer and a poor performance status.2019
- Author(s)
  Nakashima K, Kimura M, Akamatsu H, Daga H, Imai H, Taira T, Ko R, Hisamatsu Y, Nishino K, Sugimoto T, Miyashita Y, Takahashi T.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 印刷中
- DOI
  10.1093/jjco/hyz041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Genetic Profiling of Non-Small Cell Lung Cancer at Development of Resistance to First- or Second-Generation EGFR-TKIs by CAPP-Seq Analysis of Circulating Tumor DNA.2019
- Author(s)
  Otsubo K, Sakai,K, Takeshita M, Harada D, Azuma K, Ota K, Akamatsu H, Goto K, Horiike A, Kurata T, Nakagaki N, Nosaki K, Iwama E, Nakanishi Y, Nishio N, Okamoto I.
- Journal Title
  
  The Oncologist
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Osimertinib in Japanese patients with EGFR T790M mutation-positive advanced non-small-cell lung cancer: AURA3 trial.2018
- Author(s)
  Akamatsu H, Katakami N, Okamoto I, Kato T, Kim YH, Imamura F, Shinkai M, Hodge RA, Uchida H, Hida T.
- Journal Title
  
  Lung Cancer
  
  Volume: 109 Pages: 1930-1938
- DOI
  10.1111/cas.13623
- NAID
  120006496875
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Randomized Phase III Study of Cisplatin With Pemetrexed and Cisplatin With Vinorelbine for Completely Resected Nonsquamous Non-Small-Cell Lung Cancer: The JIPANG Study Protocol.2018
- Author(s)
  Akamatsu H, Koh Y, Ozawa Y, Fujimoto D, Hata A, Katakami N, Tomii K, Shimokawa T, Yamamoto N.
- Journal Title
  
  Clin Lung Cancer
  
  Volume: 19
- DOI
  10.1016/j.cllc.2018.08.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K00044, KAKENHI-PROJECT-18K07271
[Journal Article] Correlation between immune-related adverse events and efficacy in non-small cell lung cancer treated with nivolumab2018
- Author(s)
  Sato K
- Journal Title
  
  Lung Cancer
  
  Volume: 115 Pages: 71-74
- DOI
  10.1016/j.lungcan.2017.11.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06878, KAKENHI-PROJECT-15K09226, KAKENHI-PROJECT-16K19464
[Journal Article] EGFR mutation analysis for prospective patient selection in AURA3 phase III trial of osimertinib versus platinum-pemetrexed in patients with EGFR T790M-positive advanced non-small-cell lung cancer.2018
- Author(s)
  John T, Akamatsu H, Delmonte A, Su WC, Lee JS, Chang GC, Huang X, Jenkins S, Wu YL.
- Journal Title
  
  Lung Cancer
  
  Volume: 126 Pages: 133-138
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Journal Article] Exploration of resistance mechanisms for epidermal growth factor receptor-tyrosine kinase inhibitors based on plasma analysis by digital polymerase chain reaction and next-generation sequencing.2018
- Author(s)
  Iwama E, Sakai K, Azuma K, Harada D, Nosaki K, Hotta K, Nishio M, Kurata T, Fukuhara T, Akamatsu H, Goto K, Shimose T, Kishimoto J, Nakanishi Y, Nishio K, Okamoto I.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Pages: 3921-3933
- DOI
  10.1111/cas.13820
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271, KAKENHI-PROJECT-18K15214, KAKENHI-PLANNED-17H06404
[Journal Article] Alectinib for patients with ALK rearrangement-positive non-small cell lung cancer and a poor performance status (Lung Oncology Group in Kyushu 1401)2017
- Author(s)
  Iwama E, Goto Y, Akamatsu H, et al.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 17 Pages: 1161-1166
- DOI
  10.1016/j.jtho.2017.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19464, KAKENHI-PROJECT-15K09226
[Journal Article] Nivolumab induced radiation recall pneumonitis after two years of radiotherapy2017
- Author(s)
  Shibaki R, Akamatsu H, Koh Y, et al.
- Journal Title
  
  Ann Oncol
  
  Volume: epub Pages: 1404-1405
- DOI
  10.1093/annonc/mdx115
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19464, KAKENHI-PROJECT-15K06878, KAKENHI-PROJECT-15K09226
[Journal Article] Osimertinib or Platinum-Pemetrexed in EGFR T790M-Positive Lung Cancer.2017
- Author(s)
  Mok TS, Wu Y-L, Akamatsu H, et al.
- Journal Title
  
  New England Journal of Medicine
  
  Volume: 7 Pages: 629-640
- DOI
  10.1056/nejmoa1612674
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19464
[Journal Article] Detection of the T790M mutation of EGFR in plasma of advanced non-small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors (West Japan oncology group 8014LTR study).2016
- Author(s)
  Takahama T, Sakai K, Takeda M, Azuma K, Hida T, Hirabayashi M, Oguri T, Tanaka H, Ebi N, Sawa T, Bessho A, Tachihara M, Akamatsu H, Bandoh S, Himeji D, Ohira T, Shimokawa M, Nakanishi Y, Nakagawa K, Nishio K.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Pages: 58492-58499
- DOI
  10.18632/oncotarget.11303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462138, KAKENHI-PROJECT-16K19464
[Journal Article] Applicability of the Japanese equation for estimating glomerular filtration rate in patients with advanced-stage thoracic cancer.2016
- Author(s)
  Kikuchi T, Akamatsu H, Mori K, Tanaka A, Kanai K, Hayata A, Tokudome N, Akamatsu K, Koh Y, Nakanishi M, Ueda H, Yamamoto N
- Journal Title
  
  Respir Investig
  
  Volume: 54 Pages: 479-483
- DOI
  10.1016/j.resinv.2016.05.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K18456, KAKENHI-PROJECT-16K19464
[Journal Article] Disease flare after gefitinib discontinuation.2015
- Author(s)
  Akamatsu H, Ono A, Shukuya T, Tsuya A, Nakamura Y, Kenmotsu H, Naito T, Murakami H, Endo M, Nakajima T, Yamamoto N
- Journal Title
  
  Respir Investig
  
  Volume: 53 Pages: 68-72
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Disease flare after gefitinib discontinuation.2015
- Author(s)
  Akamatsu H, Ono A, Shukuya T
- Journal Title
  
  Respir Investig.
  
  Volume: 53(2) Pages: 68-72
- DOI
  10.1016/j.resinv.2014.10.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] The efficacy of amrubicin on central nervous system metastases originating from small-cell lung cancer: a case series of eight patients.2015
- Author(s)
  Miura S, Kaira K, Kaira R, Akamatsu H, Ono A, Shukuya T, Tsuya A, Nakamura Y, Kenmotsu H, Naito T, Murakami H, Takahashi T, Endo M, Yamamoto N.
- Journal Title
  
  Invest New Drugs.
  
  Volume: epub ahead of print
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Comparison of platinum combination re-challenge therapy and docetaxel monotherapy in non-small cell lung cancer patients previously treated with platinum-based chemoradiotherapy.2015
- Author(s)
  Imai H, Kaira K, Akamatsu H, et al.
- Journal Title
  
  Springerplus.
  
  Volume: 31:4 Pages: 152-152
- DOI
  10.1186/s40064-015-0929-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Disease flare after gefitinib discontinuation2015
- Author(s)
  Hiroaki Akamatsu
- Journal Title
  
  Respir Investig
  
  Volume: 53 Pages: 68-72
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Journal Article] Prognostic significance of diabetes mellitus in locally advanced non-small cell lung cancer.2015
- Author(s)
  Imai H, Kaira K, Mori K, Ono A, Akamatsu H, et al.
- Journal Title
  
  BMC Cancer
  
  Volume: 15 Pages: 989-989
- DOI
  10.1186/s12885-015-2012-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Prognostic impact of cancer cachexia in patients with advanced non-small cell lung cancer.2015
- Author(s)
  Kimura M, Naito T, Kenmotsu H, Taira T, Wakuda K, Oyakawa T, Hisamatsu Y, Tokito T, Imai H, Akamatsu H, Ono A, Kaira K, Murakami H, Endo M, Mori K, Takahashi T, Yamamoto N.
- Journal Title
  
  Support Care Cancer
  
  Volume: 23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Identification of actionable mutations in malignant pleural mesothelioma.2015
- Author(s)
  Takehito Shukuya
- Journal Title
  
  Lung Cancer.
  
  Volume: 86 Pages: 35-40
- DOI
  10.1016/j.lungcan.2014.08.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501363, KAKENHI-PROJECT-24591186, KAKENHI-PROJECT-25860658, KAKENHI-PROJECT-26870509
[Journal Article] The effect of gefitinib in patients with postoperative recurrent non-small cell lung cancer harboring mutations of the epidermal growth factor receptor.2015
- Author(s)
  Ko R, Kenmotsu H, Akamatsu H, et al.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 20(4) Pages: 668-73
- DOI
  10.1007/s10147-014-0761-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Comparison of platinum combination re-challenge therapy and docetaxel monotherapy in non-small cell lung cancer patients previously treated with platinum-based chemoradiotherapy.2015
- Author(s)
  Imai H, Kaira K, Mori K, Ono A, Akamatsu H, Taira T, Yoshino R, Kenmotsu H, Saitoh J, Harada H, Naito T, Murakami H, Tomizawa Y, Matsuura M, Saito R, Nakajima T, Yamada M, Takahashi T.
- Journal Title
  
  Springerplus
  
  Volume: 4 Pages: 152-152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Progression-free survival, post-progression survival, and tumor response as surrogate markers for overall survival in patients with extensive small cell lung cancer.2015
- Author(s)
  Imai H, Mori K, Wakuda K, Ono A, Akamatsu H, Shukuya T, Taira T, Kenmotsu H, Naito T, Kaira K, Murakami H, Endo M, Nakajima T, Yamamoto N, Takahashi T.
- Journal Title
  
  Ann Thorac Med.
  
  Volume: 10 Pages: 61-65
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Progression-free survival, post-progression survival, and tumor response as surrogate markers for overall survival in patients with extensive small cell lung cancer.2015
- Author(s)
  Imai H, Mori K, Wakuda K, Ono A, Akamatsu H,
- Journal Title
  
  Ann Thorac Med.
  
  Volume: 10(1) Pages: 61-66
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Progression of Irreversible Airflow Limitation in Asthma: Correlation with Severe Exacerbations.2015
- Author(s)
  Matsunaga K, Hirano T, Oka A, Tanaka A, Kanai K, Kikuchi T, Hayata A, Akamatsu H, Akamatsu K, Koh Y, Nakanishi M, Minakata Y, Yamamoto N
- Journal Title
  
  J Allergy Clin Immunol Pract.
  
  Volume: 3 Pages: 759-64
- DOI
  10.1016/j.jaip.2015.05.005
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09187, KAKENHI-PROJECT-26461489, KAKENHI-PROJECT-25461502, KAKENHI-PROJECT-26870509
[Journal Article] The efficacy of amrubicin on central nervous system metastases originating from small-cell lung cancer: a case series of eight patients.2015
- Author(s)
  Miura S, Kaira K, Akamatsu H, et al.
- Journal Title
  
  Invest New Drugs.
  
  Volume: 33(3) Pages: 55-60
- DOI
  10.1007/s10637-015-0233-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Toxicity and efficacy of chemotherapy for non-small cell lung cancer with cavitary lesions.2014
- Author(s)
  Tokito T, Shukuya T, Akamatsu H, Ono A, Taira T, Kenmotsu H, Naito T, Murakami H, Takahashi T, Endo M, Mori K, Yamamoto N.
- Journal Title
  
  Respir Investig
  
  Volume: 52
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Changes in forced expiratory volume in 1 second over time in patients with controlled asthma at baseline.2014
- Author(s)
  Matsunaga K, Ichikawa T, Oka A, Morishita Y, Kanai K, Hiramatsu M, Akamatsu H, Kawabata H, Kikuchi T, Akamatsu K, Hirano T, Kou Y, Nakanishi M, Minakata Y, Yamamoto N.
- Journal Title
  
  Respir Med
  
  Volume: 108 Pages: 976-982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Multiplexed molecular profiling of lung cancer using pleural effusion2014
- Author(s)
  Akamatsu H, Koh Y, Kenmotsu H, Naito T, Serizawa M, Kimura M, Mori K, Imai H, Ono A, Shukuya T, Taira T, Murakami H, Ohde Y, Endo M, Nakajima T, Takahashi T, Yamamoto N
- Journal Title
  
  J Thorac Oncol
  
  Volume: 9 Pages: 1048-1052
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Identification of actionable mutations in malignant pleural mesothelioma.2014
- Author(s)
  Shukuya T, Serizawa M, Watanabe M, Akamatsu H, Abe M, Imai H, Tokito T, Ono A, Taira T, Kenmotsu H, Naito T, Murakami H, Takahashi T, Endo M, Ohde Y, Nakajima T, Yamamoto N, Koh Y.
- Journal Title
  
  Lung Cancer
  
  Volume: 86 Pages: 35-40
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Assessment of mutational profile of Japanese lung adenocarcinoma patients by multitarget assays: a prospective, single-institute study.2014
- Author(s)
  Serizawa M, Koh Y, Kenmotsu H, Isaka M, Murakami H, Akamatsu H, Mori K, Abe M, Hayashi I, Taira T, Maniwa T, Takahashi T, Endo M, Nakajima T, Ohde Y, Yamamoto N.
- Journal Title
  
  Cancer
  
  Volume: 15 Pages: 1471-81
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] The effect of gefitinib in patients with postoperative recurrent non-small cell lung cancer harboring mutations of the epidermal growth factor receptor.2014
- Author(s)
  Ko R, Kenmotsu H, Hisamatsu Y, Akamatsu H, Omori S, Nakashima K, Oyakawa T, Wakuda K, Shukuya T, Ono A, Imai H, Taira T, Naito T, Murakami H, Mori K, Endo M, Ohde Y, Takahashi K, Takahashi T.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: epub ahead of print
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Individual-level data on the relationships of progression-free survival and post-progression survival with overall survival in patients with advanced non-squamous non-small cell lung cancer patients who received second-line chemotherapy.2014
- Author(s)
  Imai H, Mori K, Ono A, Akamatsu H, Taira T, Kenmotsu H, Naito T, Kaira K, Murakami H, Endo M, Nakajima T, Takahashi T.
- Journal Title
  
  Med Oncol
  
  Volume: 31 Pages: 88-88
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Journal Article] Comparison of cisplatin plus pemetrexed and cisplatin plus gemcitabine for the treatment of malignant pleural mesothelioma in Japanese patients.2014
- Author(s)
  Shukuya T, Takahashi T, Imai H, Tokito T, Ono A, Akamatsu H, Taira T, Kenmotsu H, Naito T, Murakami H, Endo M, Yamamoto N.
- Journal Title
  
  Respir Investig
  
  Volume: 52 Pages: 101-106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870509
[Patent] METHOD FOR PREDICTING THE DURABLE EFFICACY OF EGFR TYROSINE KINASES INHIBITORS IN EGFR-MUTATED NON-SMALL LUNG CANCER2017
- Inventor(s)
  山本信之、洪泰浩、赤松弘朗
- Industrial Property Rights Holder
  山本信之、洪泰浩、赤松弘朗
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] がん免疫療法ガイドライン改訂版2018
- Author(s)
  赤松弘朗
- Organizer
  第16回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] 肺癌診療ガイドライン改訂の要点2018
- Author(s)
  赤松弘朗
- Organizer
  第58回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] Predictive values of serum protein levels in advanced non-small-cell lung cancer patients treated with nivolumab.2018
- Author(s)
  Oyanagi J, Koh Y, Akamatsu H, Kanai K, Hayata A, Tokudome N, Akamatsu K, Nakanishi M, Ueda H, Yamamoto N:
- Organizer
  American Association for Cancer Research Annual Meeting
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] Predictive impact of sequential evaluation of PD-L1-expressing circulating tumor cells in NSCLC patients treated with nivolumab.2018
- Author(s)
  Koh Y, Akamatsu H, Mori K, Kanai K, Hayata A, Tokudome N, Higuchi M, Akamatsu K, Nakanishi M, Ueda H, Yamamoto N
- Organizer
  American Association for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] 肺癌薬物療法アップデート肺がんの薬物療法2018
- Author(s)
  赤松弘朗
- Organizer
  第16回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07271
[Presentation] Predictive impact of PD-L1-expressing circulating tumor cells in NSCLC patients treated with nivolumab.2017
- Author(s)
  Shibaki R, Akamatsu H, Koh Y, Yamamoto N, et al.
- Organizer
  2017 American Society of Clinical Oncology
- Place of Presentation
  Chicago, USA
- Year and Date
  2017-06-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19464
[Presentation] Sequential tracking of PD-L1 expression on circulating tumor cells in NSCLC patients treated with nivolumab.2017
- Author(s)
  Akamatsu H, Koh Y, Yamamoto N, et al.
- Organizer
  EORTC-NCI-AACR meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19464
[Presentation] Sequential tracking of PD-L1 expression on circulating tumor cells in NSCLC patients treated with nivolumab2017
- Author(s)
  Akamatsu H
- Organizer
  AACR-NCI-EORTC 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] PD-L1 expression on circulating tumor cells and its comparison with tumor tissues in Japanese lung cancer patients.2017
- Author(s)
  Akamatsu H
- Organizer
  AACR 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] Correlation Between Immune-Related Adverse Events and Efficacy in Non-Small Cell Lung Cancer Treated with Nivolumab.2017
- Author(s)
  Sato K, Akamatsu H, Murakami E, et al.
- Organizer
  World Conference on Lung Cancer 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19464
[Presentation] A prospective biomarker study using digital PCR method in EGFR mutated, advanced lung adenocarcinoma patients treated with afatinib2016
- Author(s)
  Akamatsu H
- Organizer
  American Association for Cancer Research Annual Meeting 2016
- Place of Presentation
  New Orleans, Louisiana, USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] Establishment of multiplexed ultra-sensitive detection of epidermal growth factor receptor mutations using picodroplet digital PCR2015
- Author(s)
  Hiroaki Akamatsu, Yasuhiro Koh, Masaru Watanabe, Takashi Kikuchi, Masanori Nakanishi, Kazuto Matsunaga, Nobuyuki Yamamoto.
- Organizer
  American Association of Cancer Research Annual Meeting 2015
- Place of Presentation
  Pennsylvania Convention Center
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] stablishment of novel multiplexed assay to detect EGFR mutations using ultra-sensitive digital PCR2015
- Author(s)
  Hiroaki Akamatsu
- Organizer
  ESMO Asia
- Place of Presentation
  Singapore
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] Establishment of novel multiplexed assay to detect EGFR mutations using ultra-sensitive digital PCR2015
- Author(s)
  赤松弘朗、洪泰浩、山本信之ら
- Organizer
  ESMO Asia 2015
- Place of Presentation
  Suntec, Singapore
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] Establishment of multiplexed ultra-sensitive detection of epidermal growth factor receptor mutations using picodroplet digital PCR2015
- Author(s)
  Hiroaki Akamatsu
- Organizer
  American Association for Cancer Research Annual Meeting 2015
- Place of Presentation
  Philadelphia, Pennsylvania, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09226
[Presentation] Establishment of multiplexed ultra-sensitive detection of epidermal growth factor receptor mutations using picodroplet digital PCR.2015
- Author(s)
  赤松弘朗、洪泰浩、山本信之ら
- Organizer
  American Association for Cancer Research Annual Meeting 2015
- Place of Presentation
  Pennsylvania convention center, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] Early Phase Trials Using Liquid Biopsy.2015
- Author(s)
  赤松弘朗
- Organizer
  4th Japan Taiwan Oncology Phase Ⅰ Trial Conference
- Place of Presentation
  NTUH International Convention Center, Taipei, Taiwan
- Year and Date
  2015-04-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] Ongoing early phase trials using liquid biopsy2015
- Author(s)
  Hiroaki Akamatsu
- Organizer
  The 4th Japan-Taiwan Oncology Phase I Trial Conference
- Place of Presentation
  International Conference Center of National Taiwan University Hospital
- Year and Date
  2015-04-26
- Invited
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] Significance ofconsolidation chemotherapyin unresectable, locally advanced non-small cell lung cancer.2014
- Author(s)
  Hiroaki Akamatsu
- Organizer
  日本臨床腫瘍学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-26870509
[Presentation] Droplet Digital PCR を用いた EGFR 遺伝子変異のマルチプレックス検出2014
- Author(s)
  渡辺勝、洪泰浩、赤松弘朗、菊池崇史、松永和人、山本信之
- Organizer
  日本肺癌学会総会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-26870509

1. YAMAMOTO Nobuyuki (60298966)

# of Collaborated Projects: 3 results

# of Collaborated Products: 36 results
2. KOH Yasuhiro (80426519)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. KIKUCHI Takashi (40649050)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. OHIRA Tatsuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. SHIMOKAWA Toshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. MATSUNAGA Kazuto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 南方良章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 平野綱彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 金井一修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 坂井和子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 西尾和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Akamatsu Hiroaki 赤松 弘朗

Research Projects

Research Products

Co-Researchers

遺伝子変異陽性肺癌におけるheterogeneityが治療効果に与える影響の解明Principal InvestigatorOngoing

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Review Section

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Exploratory biomarker analysis to predict the efficacy of immune checkpoint inhibitors using cell-free DNAPrincipal Investigator

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Research Institution

Multiplex mutation detection using digital PCR method and its clinical utility

Principal Investigator

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Exploratory analyses of comprehensive and quantitative mutation profiling using cell-free DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Book] 肺癌診療ガイドライン 2018年版 第5版2018

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[Book] がん免疫療法ガイドライン 第2版2018

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[Book] 分子標的時代における治療推奨の重みづけをどうするか？2016

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[Book] どのような肺がん患者に化学療法が行われるか2016

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[Book] デジタルPCRの原理と臨床腫瘍学での有用性2016

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[Book] 各種がんにおける化学療法 1肺癌2016

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[Book] 抗癌薬の副作用対策2016

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[Book] 呼吸器疾患診療最新ガイドライン2014

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[Book] EBMの手法による肺癌診療ガイドライン2014年版2014

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[Book] 現在進行中の大規模無作為化比較試験2014

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[Book] 腫瘍病理鑑別診断アトラス 肺癌2014

Author(s)

Publisher

Akamatsu Hiroaki 赤松弘朗

[Book] 肺癌診療ガイドライン 2018年版　第5版2018

[Book] がん免疫療法ガイドライン　第2版2018

[Book] 腫瘍病理鑑別診断アトラス肺癌2014

[Book] がん薬物療法の作用機序　殺細胞性抗悪性腫瘍薬　白金製剤･アルキル化薬･抗がん性抗生物質2014