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Hiramatsu Kosuke  平松 宏祐

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HIRAMATSU Kosuke  平松 宏祐

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Researcher Number 10650591
Other IDs
Affiliation (Current) 2025: 大阪大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help 2025: 大阪大学, 医学部附属病院, 助教
2019 – 2023: 大阪大学, 医学部附属病院, 助教
2017 – 2018: 高知大学, 医学部附属病院, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Basic Section 50010:Tumor biology-related / Obstetrics and gynecology
Except Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related
Keywords
Principal Investigator
卵巣癌 / LSR / 子宮体癌 / 脂質代謝
Except Principal Investigator
iTRAQ / Antibody-drug conjugate / Leiomyosarcoma / oligonucleotide / CDC25 / leiomyosarcoma … More / KIF4A / LMS / 子宮平滑筋肉腫 / 抗体薬物複合体 / 中和抗体 / 子宮癌肉腫 / HPV / single-cell analysis / cervical intraneoplasia / gynecology / 産婦人科学関連 / 生存率 / がん登録 / サバイバー / 卵巣がん / 子宮体がん / 多施設共同研究 / 腹腔鏡 / 低侵襲手術 / 子宮頸癌 Less
  • Research Projects

    (9 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (13 People)
  •  Development of Novel Therapeutics for Uterine Leiomyosarcoma Based on Comprehensive Membrane Protein Profiling

    • Principal Investigator
      松崎 慎哉
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      The University of Osaka
  •  Development of novel therapeutics for uterine leiomyosarcoma mediated by KIF4A and CDC25

    • Principal Investigator
      中川 慧
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Osaka University
  •  Lipid metabolism via LSR in ovarian cancer and the inhibitory effect of anti-LSR monoclonal antibodyPrincipal Investigator

    • Principal Investigator
      平松 宏祐
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Osaka University
  •  Elucidation of the mechanism of disease progression of cervical atypical epithelium and search for new markers by single cell analysis

    • Principal Investigator
      木村 敏啓
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Osaka University
  •  Quantitative Proteomic Approaches for Drug Target Discovery in Uterine Carcinosarcoma

    • Principal Investigator
      松崎 慎哉
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Osaka International Cancer Institute
  •  Epidemiologic and clinical analysis of corpus cancer and ovarian cancer from the Population-Based Osaka Cancer Registry.

    • Principal Investigator
      Yagi Asami
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Osaka University
  •  Verification of Risk Factors for Recurrence of Minimally Invasive Surgery for Cervical Cancer in Japan

    • Principal Investigator
      Kobayashi Eiji
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Osaka University
  •  Analysis of lipid metabolism via LSR and anti-tumor effect of anti-LSR antibody in ovarian cancerPrincipal Investigator

    • Principal Investigator
      HIRAMATSU Kosuke
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Osaka University
  •  Biological function of LSR in ovarian cancerPrincipal Investigator

    • Principal Investigator
      HIRAMATSU Kosuke
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kochi University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Tumor cell-expressed lipolysis-stimulated lipoprotein receptor negatively regulates T-cell function2024

    • Author(s)
      Masashi Funauchi, Satoshi Serada, Kosuke Hiramatsu, Eiji Funajima, Mizuki Kanda, Yoshikazu Nagase, Satoshi Nakagawa, Tomoharu Ohkawara, Minoru Fujimoto, Yuji Suzuki, Yutaka Ueda, Tadashi Kimura, Tetsuji Naka
    • Journal Title

      Int J Cancer.

      Volume: 1;154(3) Issue: 3 Pages: 425-433

    • DOI

      10.1002/ijc.34738

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09594
  • [Journal Article] Anti-lipolysis-stimulated lipoprotein receptor monoclonal antibody as a novel therapeutic agent for endometrial cancer2022

    • Author(s)
      Nagase Yoshikazu、Hiramatsu Kosuke、Funauchi Masashi、Shiomi Mayu、Masuda Tatsuo、Kakuda Mamoru、Nakagawa Satoshi、Miyoshi Ai、Matsuzaki Shinya、Kobayashi Eiji、Kimura Toshihiro、Serada Satoshi、Ueda Yutaka、Naka Tetsuji、Kimura Tadashi
    • Journal Title

      BMC Cancer

      Volume: 22 Issue: 1 Pages: 679-679

    • DOI

      10.1186/s12885-022-09789-6

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09657
  • [Journal Article] Improved long-term survival of corpus cancer in Japan: A 40-year population-based analysis2022

    • Author(s)
      Yagi A, Ueda Y, Ikeda S, Miyoshi A, Nakagawa S, Hiramatsu K, Kobayashi E, Kimura T, Ito Y, Nakayama T, Nakata K, Morishima T, Miyashiro I, Kimura T.
    • Journal Title

      Int J Cancer

      Volume: 150 Issue: 2 Pages: 232-242

    • DOI

      10.1002/ijc.33799

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09470, KAKENHI-PROJECT-20K18952, KAKENHI-PROJECT-20K18869, KAKENHI-PROJECT-23K21510
  • [Journal Article] LSR Antibody Therapy Inhibits Ovarian Epithelial Tumor Growth by Inhibiting Lipid Uptake2018

    • Author(s)
      Hiramatsu K, Serada S, Enomoto T, Takahashi Y, Nakagawa S, Nojima S, Morimoto A, Matsuzaki S, Yokoyama T, Takahashi T, Fujimoto M, Takemori H, Ueda Y, Yoshino K, Morii E, Kimura T, Naka T.
    • Journal Title

      Cancer Research

      Volume: 78 Pages: 516-527

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16882
  • [Presentation] Metabolome analysis shows that arachidonic acid promotes cell proliferation in epithelial ovarian cancer.2023

    • Author(s)
      H. Sakaguchi-Mukaida, K. Hiramatsu, M. Kakuda, S. Nakagawa, E. Kobayashi, T. Kimura, Y. Ueda and T. Kimura
    • Organizer
      第65回日本婦人科腫瘍学会学術講演会
    • Data Source
      KAKENHI-PROJECT-22K09594
  • [Presentation] Certain lipid molecules identified by metabolome analysis promoted the cell proliferation of epithelial ovarian cancer2023

    • Author(s)
      H. Sakaguchi-Mukaida, K. Hiramatsu, M. Kakuda, S. Nakagawa, E. Kobayashi, T. Kimura, Y. Ueda and T. Kimura
    • Organizer
      The 82nd Annual Meeting of the Japanese Cancer Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09594
  • [Presentation] Metabolome analysis shows that certain lipid components promote cell proliferation of LSR-positive epithelial ovarian cancer2023

    • Author(s)
      H. Sakaguchi, K. Hiramatsu, M. Kakuda, S. Nakagawa, A. Miyoshi, E. Kobayashi, T. Kimura, Y. Ueda and T. Kimura
    • Organizer
      第75回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-22K09594
  • [Presentation] LSR is a novel prognostic factor by regulating cell proliferation via MEK/ERK pathway in endometrial cancer: Analysis of signal transduction, bioinformatics, and in vitro/in vivo study2021

    • Author(s)
      Yoshikazu Nagase, Kosuke Hiramatsu, Satoshi Nakagawa, Shinya Matsuzaki, Toshihiro Kimura, Satoshi Serada, Yutaka Ueda, Tetsuji Naka, Tadashi Kimura.
    • Organizer
      AACR ANNUAL MEETING 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] A population-based analysis of uterine corpus cancer using the Osaka Cancer Registry data2021

    • Author(s)
      Asami Yagi, Yutaka Ueda, Sayaka Ikeda, Ai Miyoshi, Satoshi Nakagawa, Kosuke Hiramatsu, Eiji Kobayashi, Toshihiro Kimura, Yuri Ito, Tomio Nakayama, Kayo Nakata, Toshitaka Morishima, Isao Miyashiro, Tadashi Kimura
    • Organizer
      第59回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K09470
  • [Presentation] LSR is a novel therapeutic target via cell proliferation and invasion in endometrial cancer: analysis of signal transduction, bioinformatics, and in vitro/in vivo study2021

    • Author(s)
      Yoshikazu Nagase, Kosuke Hiramatsu, Masashi Funauchi, Mayu Shiomi, Tatsuo Masuda, Satoshi Nakagawa, Shinya Matsuzaki, Eiji Kobayashi, Toshihiro Kimura, Yutaka Ueda, Tetsuji Naka, Tadashi Kimura.
    • Organizer
      第73回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] LSR activates MEK/ERK pathway and promotes cell proliferation and invasion in endometrial cancer: Analysis of bioinformatics-based signal transduction2021

    • Author(s)
      Yoshikazu Nagase, Kosuke Hiramatsu, Satoshi Nakagawa, Shinya Matsuzaki, Toshihiro Kimura, Satoshi Serada, Yutaka Ueda, Tetsuji Naka, Tadashi Kimura.
    • Organizer
      第63回日本婦人科腫瘍学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] Epidemiological and clinical analysis of uterine corpus cancer using the population-based data of the Osaka Cancer Registry2021

    • Author(s)
      Asami Yagi, Yutaka Ueda, Satoshi Nakagawa, Kosuke Hiramatsu, Ai Miyoshi, Eiji Kobayashi, Toshihiro Kimura, Tadashi Kimura
    • Organizer
      第73回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-21K09470
  • [Presentation] LSR promotes tumor progression by regulating signal transduction of apoptosis and ferroptosis in endometrial cancer2021

    • Author(s)
      Yoshikazu Nagase, Kosuke Hiramatsu, Masashi Funauchi, Satoshi Nakagawa, Shinya Matsuzaki, Eiji Kobayashi, Toshihiro Kimura, Satoshi Serada, Yutaka Ueda, Tetsuji Naka, Tadashi Kimura.
    • Organizer
      22nd European Congress on Gynaecological Oncology of ESGO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] 大阪府がん登録データを用いた子宮体がんの動向および臨床的観点からの解析2021

    • Author(s)
      八木麻未, 上田豊. 伊藤ゆり, 中山富雄, 池田さやか, 中川慧, 平松宏祐, 三好愛, 小林栄仁, 木村敏啓, 森島敏隆, 宮代勲, 木村正
    • Organizer
      日本がん登録協議会第30回学術集会
    • Data Source
      KAKENHI-PROJECT-21K09470
  • [Presentation] Lipolysis-stimulated lipoprotein receptor regulates cell proliferation and invasion, and associates with poor prognosis in endometrial cancer.2021

    • Author(s)
      Yoshikazu Nagase, Kosuke Hiramatsu, Masashi Funauchi, Mayu Shiomi, Tatsuo Masuda, Satoshi Nakagawa, Shinya Matsuzaki, Eiji Kobayashi, Toshihiro Kimura, Yutaka Ueda, Tetsuji Naka, Tadashi Kimura.
    • Organizer
      第62回日本婦人科腫瘍学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] LSR activates MAPK pathway and promotes cell proliferation and invasion in endometrial cancer : Analysis of bioinformatics-based signal transduction2021

    • Author(s)
      Yoshikazu Nagase, Kosuke Hiramatsu, Satoshi Nakagawa, Shinya Matsuzaki, Toshihiro Kimura, Satoshi Serada, Yutaka Ueda, Tetsuji Naka, Tadashi Kimura.
    • Organizer
      IGCS (International Gynecologic Cancer Society) Annual Global Meeting 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] LSR activates MAPK signaling pathway and MMPs in endometrial cancer: in-vitro/in-vivo and bioinformatic analysis2021

    • Author(s)
      Yoshikazu Nagase, Kosuke Hiramatsu, Satoshi Nakagawa, Shinya Matsuzaki, Toshihiro Kimura, Satoshi Serada, Yutaka Ueda, Tetsuji Naka, Tadashi Kimura.
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] 本邦における子宮体がんの動向: 大阪府がん登録データを用いて2021

    • Author(s)
      八木麻未, 上田豊, 中川慧, 平松宏祐, 三好愛, 小林栄仁, 木村敏啓, 木村正
    • Organizer
      第63回 日本婦人科腫瘍学会学術講演会
    • Data Source
      KAKENHI-PROJECT-21K09470
  • [Presentation] 卵巣癌細胞膜発現タンパクであるLSRを標的とした新規抗体は卵巣癌の脂質代謝阻害やアポトーシス誘導により抗腫瘍効果を示す2021

    • Author(s)
      平松宏祐
    • Organizer
      第63回日本婦人科腫瘍学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] Lipolysis-stimulated lipoprotein receptor in endometrial cancer regulates cell proliferation in vitro and associates with poor prognosis in vivo.2020

    • Author(s)
      Yoshikazu Nagase, Kosuke Hiramatsu, Masashi Funauchi, Satoshi Nakagawa, Shinya Matsuzaki, Eiji Kobayashi, Toshihiro Kimura, Yutaka Ueda, Tetsuji Naka, Tadashi Kimura
    • Organizer
      第72回日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] LSR in endometrial cancer: A novel prognostic factor by regulating cell proliferation and invasion via MEK/ERK pathway2020

    • Author(s)
      Yoshikazu Nagase, Kosuke Hiramatsu, Masashi Funauchi, Mayu Shiomi, Satoshi Nakagawa, Shinya Matsuzaki, Eiji Kobayashi, Toshihiro Kimura, Yutaka Ueda, Tetsuji Naka, Tadashi Kimura
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] Lipolysis-stimulated lipoprotein receptor regulates cell proliferation and invasion, and associates with poor prognosis in endometrial cancer.2020

    • Author(s)
      Yoshikazu Nagase, Kosuke Hiramatsu, Masashi Funauchi, Satoshi Nakagawa, Shinya Matsuzaki, Eiji Kobayashi, Toshihiro Kimura, Yutaka Ueda, Tetsuji Naka, Tadashi Kimura
    • Organizer
      第62回日本婦人科腫瘍学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] Elaidic acid promotes cell proliferation and migration via LSR in epithelial ovarian cancer2019

    • Author(s)
      Masashi Funauchi, Kosuke Hiramatsu, Satoshi Serada, Minoru Fujimoto, Yutaka Ueda, Tadashi Kimura, Tetsuji Naka
    • Organizer
      ESGO 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] LSR promotes cell proliferation and migration subsequent to uptake of fatty acid in epithelial ovarian cancer2019

    • Author(s)
      Kosuke Hiramatsu, Satoshi Serada, Minoru Fujimoto, Tadashi Kimura, Tetsuji Naka
    • Organizer
      AACR 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] Fatty acid promotes cell proliferation and migration via LSR in ovarian cancer2019

    • Author(s)
      Kosuke Hiramatsu, Satoshi Serada, Minoru Fujimoto, Shinya Matsuzaki, Yutaka Ueda, Tadashi Kimura, Tetsuji Naka
    • Organizer
      第71回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] Fatty acid promotes cell proliferation and migration via LSR in epithelial ovarian cancer2019

    • Author(s)
      Kosuke Hiramatsu, Satoshi Serada, Minoru Fujimoto, Shinya Matsuzaki, Yutaka Ueda, Tadashi Kimura, Tetsuji Naka
    • Organizer
      第61回日本婦人科腫瘍学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K16748
  • [Presentation] LSR promotes lipid metabolism via beta oxidation and contributes cell viability in epithelial ovarian cancer2018

    • Author(s)
      Kosuke Hiramatsu, Satoshi Serada, Minoru Fujimoto, Shinya Matsuzaki, Yutaka Ueda, Kiyoshi Yoshino, Tadashi Kimura, Tetsuji Naka
    • Organizer
      AACR annual meeting 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16882
  • [Presentation] LSR promotes lipid metabolism and contributes cell viability in low glucose environment in epithelial ovarian cancer2018

    • Author(s)
      Kosuke Hiramatsu, Satoshi Serada, Minoru Fujimoto, Shinya Matsuzaki, Yutaka Ueda, Tadashi Kimura, Tetsuji Naka
    • Organizer
      IGCS 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16882
  • [Presentation] 卵巣癌細胞膜発現タンパク質であるLSRを標的とした新規抗体治療法の開発とその機能解析2018

    • Author(s)
      平松宏祐
    • Organizer
      第6回婦人科バイオマーカー研究会
    • Data Source
      KAKENHI-PROJECT-17K16882
  • [Presentation] LSR promotes lipid uptake, beta-oxidation and subsequent tumor growth in ovarian cancer2017

    • Author(s)
      Kosuke Hiramatsu, Satoshi Serada, Minoru Fujimoto, Shinya Matsuzaki, Yutaka Ueda, Kiyoshi Yoshino, Tadashi Kimura, Tetsuji Naka
    • Organizer
      ESGO 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16882
  • [Presentation] LSR promotes beta-oxidation via lipid uptake and subsequent tumor growth in ovarian cancer2017

    • Author(s)
      Kosuke Hiramatsu, Satoshi Serada, Minoru Fujimoto, Shinya Matsuzaki, Yutaka Ueda, Kiyoshi Yoshino, Tadashi Kimura, Tetsuji Naka
    • Organizer
      第76回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16882
  • [Presentation] LSR promotes ovarian cancer cell growth following the activation of β-oxidation and its antibody inhibits lipid catabolism2017

    • Author(s)
      Kosuke Hiramatsu, Satoshi Serada, Takayuki Enomoto, Takuhei Yokoyama, Yusuke Takahashi, Minoru Fujimoto, Kiyoshi Yoshino, Tadashi Kimura, Tetsuji Naka
    • Organizer
      AACR annual meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16882
  • 1.  上田 豊 (10346215)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 10 results
  • 2.  中川 慧 (30650593)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 10 results
  • 3.  木村 敏啓 (90584524)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 10 results
  • 4.  Kobayashi Eiji (50614773)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 9 results
  • 5.  角田 守 (30923031)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 6.  三好 愛 (50880712)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 7.  松崎 慎哉 (00467565)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  Yagi Asami (30793450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 9.  三上 幹男 (30190606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  金尾 祐之 (80372621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  中谷 英仁 (80627670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  武隈 宗孝 (80644062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  木村 正 (90240845)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results

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